$95+ Cheap flights from Missouri to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SFO
huhti 16 — huhti 231
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to San FranciscoExplore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on maaliskuu 17, 2026.
Explore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on maaliskuu 17, 2026.
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/68:43 pm
MCI
- SFO
1 stop25h 22m
Frontier
pe 4/109:00 pm
SFO
- MCI
1 stop20h 58m
Frontier
Deal found 3/12![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 5/52:34 pm
MCI
- SFO
1 stop23h 08m
Frontier
pe 5/85:25 pm
SFO
- MCI
2 stops18h 24m
Frontier
Deal found 3/12![Frontier logo]()
$243
This Flightnetwork deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 4/172:15 pm
MCI
- SFO
1 stop12h 12m
Frontier
la 4/186:00 am
SFO
- MCI
1 stop6h 06m
Frontier
Deal found 3/13![Frontier logo]()
$244
This Frontier deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/68:43 pm
MCI
- SFO
1 stop5h 45m
Frontier
su 4/129:00 pm
SFO
- MCI
1 stop20h 58m
Frontier
Deal found 3/15![Frontier logo]()
$248
This Orbitz deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/205:50 pm
MCI
- SFO
1 stop7h 39m
Alaska Airlines
ke 4/229:00 am
SFO
- MCI
1 stop12h 59m
Alaska Airlines
Deal found 3/12![Alaska Airlines logo]()
$249
This Frontier deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 5/132:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
ti 5/196:00 am
SFO
- MCI
1 stop5h 49m
Frontier
Deal found 3/15![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
su 5/312:34 pm
MCI
- SFO
1 stop19h 27m
Frontier
ke 6/312:52 pm
SFO
- MCI
1 stop22h 57m
Frontier
Deal found 3/17![Frontier logo]()
$261
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/85:50 pm
MCI
- SFO
1 stop6h 53m
Multiple Airlines
la 4/116:00 am
SFO
- MCI
1 stop11h 58m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$265
This Expedia deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 3/308:38 pm
MCI
- SFO
1 stop5h 50m
Frontier
to 4/26:00 am
SFO
- MCI
1 stop12h 01m
Frontier
Deal found 3/16![Frontier logo]()
$270
This Expedia deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/294:46 pm
STL
- SFO
1 stop7h 42m
Multiple Airlines
pe 5/810:15 pm
SFO
- STL
1 stop8h 40m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$277
This Orbitz deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/18:16 pm
STL
- SFO
1 stop6h 07m
Frontier
su 4/510:57 pm
SFO
- STL
1 stop10h 25m
Frontier
Deal found 3/12![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 4/258:17 pm
STL
- SFO
1 stop14h 56m
Multiple Airlines
ti 4/282:00 pm
SFO
- STL
1 stop7h 59m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$282
Best flights from Missouri to San FranciscoDiscover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated maaliskuu 17, 2026.
Discover carefully curated flight deals from Missouri to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated maaliskuu 17, 2026.
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 4/145:18 pm
MCI
- SFO
1 stop7h 37m
United Airlines
ti 4/2112:45 pm
SFO
- MCI
Nonstop3h 38m
United Airlines
Deal found 3/12![United Airlines logo]()
$315
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 4/142:15 pm
MCI
- SFO
2 stops11h 22m
Delta
ti 4/215:59 am
SFO
- MCI
2 stops11h 07m
Delta
Deal found 3/12![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 4/234:28 pm
COU
- SFO
1 stop9h 31m
American Airlines
su 4/2612:59 am
SFO
- COU
1 stop8h 36m
American Airlines
Deal found 3/14![American Airlines logo]()
$338
This Alaska Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/12:23 pm
MCI
- SFO
1 stop10h 04m
Alaska Airlines
ke 4/88:00 am
SFO
- MCI
1 stop6h 56m
Alaska Airlines
Deal found 3/16![Alaska Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 5/293:10 pm
MCI
- SFO
2 stops9h 00m
Southwest
ke 7/2911:40 am
SFO
- MCI
2 stops8h 20m
Southwest
Deal found 3/12![Southwest logo]()
$359
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 4/187:00 am
MCI
- SFO
Nonstop4h 05m
United Airlines
ma 4/2010:50 pm
SFO
- MCI
1 stop8h 02m
United Airlines
Deal found 3/14![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 4/712:06 pm
COU
- SFO
2 stops8h 58m
American Airlines
pe 4/1012:59 am
SFO
- COU
1 stop8h 36m
American Airlines
Deal found 3/15![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 4/142:15 pm
MCI
- SFO
2 stops11h 22m
Delta
to 4/162:57 pm
SFO
- MCI
1 stop6h 46m
Delta
Deal found 3/15![Delta logo]()
$370
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 5/195:30 am
STL
- SFO
2 stops9h 05m
Southwest
to 5/282:25 pm
SFO
- STL
1 stop7h 25m
Southwest
Deal found 3/12![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 6/27:59 pm
MCI
- SFO
Nonstop3h 51m
United Airlines
to 7/304:29 pm
SFO
- MCI
Nonstop3h 46m
United Airlines
Deal found 3/12![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 4/165:21 pm
COU
- SFO
2 stops9h 32m
American Airlines
su 4/1911:28 pm
SFO
- COU
1 stop8h 18m
American Airlines
Deal found 3/13![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 5/88:25 am
STL
- SFO
Nonstop4h 20m
Southwest
ti 5/121:20 pm
SFO
- STL
1 stop6h 25m
Southwest
Deal found 3/12![Southwest logo]()
$382
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/158:30 am
STL
- SFO
Nonstop4h 43m
United Airlines
ma 4/2011:59 pm
SFO
- STL
1 stop7h 26m
United Airlines
Deal found 3/12![United Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 5/24:00 pm
SGF
- SFO
1 stop8h 47m
Delta
pe 5/811:59 pm
SFO
- SGF
1 stop9h 28m
Delta
Deal found 3/15![Delta logo]()
$414
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 6/312:25 pm
MCI
- SFO
2 stops8h 05m
Southwest
ke 6/1012:10 pm
SFO
- MCI
2 stops9h 00m
Southwest
Deal found 3/13![Southwest logo]()
$383
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 5/284:26 pm
MCI
- SFO
1 stop5h 44m
United Airlines
to 7/304:29 pm
SFO
- MCI
Nonstop3h 46m
United Airlines
Deal found 3/12![United Airlines logo]()
$359
This Alaska Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/13:50 pm
STL
- SFO
1 stop8h 37m
Alaska Airlines
ke 4/88:00 am
SFO
- STL
2 stops13h 59m
Alaska Airlines
Deal found 3/16![Alaska Airlines logo]()
$486
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/296:55 pm
SGF
- SFO
2 stops14h 50m
Delta
ti 5/1211:41 am
SFO
- SGF
1 stop8h 38m
Delta
Deal found 3/15![Delta logo]()
$464
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 6/66:41 pm
SGF
- SFO
1 stop7h 49m
United Airlines
pe 7/312:50 am
SFO
- SGF
1 stop7h 54m
United Airlines
Deal found 3/13![United Airlines logo]()
$385
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 6/38:35 am
STL
- SFO
Nonstop4h 25m
Southwest
ke 6/1012:20 pm
SFO
- STL
Nonstop3h 50m
Southwest
Deal found 3/12![Southwest logo]()
$459
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 3/276:24 pm
JLN
- SFO
1 stop6h 23m
United Airlines
ti 3/312:32 pm
SFO
- JLN
1 stop7h 12m
United Airlines
Deal found 3/12![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 6/86:30 pm
STL
- SFO
2 stops8h 00m
Southwest
pe 6/1211:00 am
SFO
- STL
2 stops9h 40m
Southwest
Deal found 3/16![Southwest logo]()
$483
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 4/239:02 am
COU
- SFO
1 stop8h 28m
United Airlines
su 4/2612:45 am
SFO
- COU
1 stop8h 10m
United Airlines
Deal found 3/13![United Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 6/101:45 pm
STL
- SFO
2 stops10h 30m
Southwest
ma 6/152:15 pm
SFO
- STL
2 stops7h 40m
Southwest
Deal found 3/12![Southwest logo]()
$490
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 5/198:30 am
STL
- SFO
Nonstop4h 41m
United Airlines
to 5/2812:12 pm
SFO
- STL
Nonstop4h 05m
United Airlines
Deal found 3/12![United Airlines logo]()
$406
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 4/46:00 am
SGF
- SFO
1 stop8h 07m
United Airlines
ti 4/710:50 pm
SFO
- SGF
1 stop9h 58m
United Airlines
Deal found 3/13![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 8/259:03 am
SGF
- SFO
1 stop6h 05m
United Airlines
la 8/2910:35 pm
SFO
- SGF
1 stop10h 08m
United Airlines
Deal found 3/11![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 4/48:30 am
SGF
- SFO
1 stop9h 02m
United Airlines
ke 4/85:00 am
SFO
- SGF
1 stop5h 49m
United Airlines
Deal found 3/13![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 4/289:02 am
COU
- SFO
1 stop8h 30m
United Airlines
la 5/210:55 pm
SFO
- COU
1 stop10h 02m
United Airlines
Deal found 3/12![United Airlines logo]()
$428
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 4/98:30 am
STL
- SFO
Nonstop4h 43m
United Airlines
su 4/1212:00 pm
SFO
- STL
Nonstop4h 24m
United Airlines
Deal found 3/12![United Airlines logo]()
$431
Last-minute flights from Missouri to San FranciscoDiscover last-minute flight deals from Missouri to San Francisco. Data last updated maaliskuu 17, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to San Francisco. Data last updated maaliskuu 17, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 3/308:38 pm
MCI
- SFO
1 stop5h 50m
Frontier
to 4/26:00 am
SFO
- MCI
1 stop12h 01m
Frontier
Deal found 3/16![Frontier logo]()
$270
This Orbitz deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/18:16 pm
STL
- SFO
1 stop6h 07m
Frontier
su 4/510:57 pm
SFO
- STL
1 stop10h 25m
Frontier
Deal found 3/12![Frontier logo]()
$281
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 4/38:43 pm
MCI
- SFO
1 stop5h 40m
Frontier
ti 4/76:00 am
SFO
- MCI
1 stop11h 58m
Frontier
Deal found 3/16![Frontier logo]()
$260
This CheapOair deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
su 4/58:28 pm
MCI
- SFO
1 stop25h 47m
Frontier
ke 4/89:00 pm
SFO
- MCI
1 stop21h 01m
Frontier
Deal found 3/16![Frontier logo]()
$271
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/68:43 pm
MCI
- SFO
1 stop25h 22m
Frontier
pe 4/109:00 pm
SFO
- MCI
1 stop20h 58m
Frontier
Deal found 3/12![Frontier logo]()
$240
This Frontier deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/68:43 pm
MCI
- SFO
1 stop5h 45m
Frontier
su 4/129:00 pm
SFO
- MCI
1 stop20h 58m
Frontier
Deal found 3/15![Frontier logo]()
$248
This Expedia deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/85:50 pm
MCI
- SFO
1 stop6h 53m
Multiple Airlines
la 4/116:00 am
SFO
- MCI
1 stop11h 58m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$265
This Frontier deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 4/98:46 pm
MCI
- SFO
1 stop5h 42m
Frontier
ma 4/136:00 am
SFO
- MCI
1 stop11h 58m
Frontier
Deal found 3/12![Frontier logo]()
$280
This Flightnetwork deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 4/172:15 pm
MCI
- SFO
1 stop12h 12m
Frontier
la 4/186:00 am
SFO
- MCI
1 stop6h 06m
Frontier
Deal found 3/13![Frontier logo]()
$244
This Orbitz deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/205:50 pm
MCI
- SFO
1 stop7h 39m
Alaska Airlines
ke 4/229:00 am
SFO
- MCI
1 stop12h 59m
Alaska Airlines
Deal found 3/12![Alaska Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 4/258:17 pm
STL
- SFO
1 stop14h 56m
Multiple Airlines
ti 4/282:00 pm
SFO
- STL
1 stop7h 59m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$282
This Expedia deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 4/294:46 pm
STL
- SFO
1 stop7h 42m
Multiple Airlines
pe 5/810:15 pm
SFO
- STL
1 stop8h 40m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$277
One-way flights from Missouri to San FranciscoSearch for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated maaliskuu 17, 2026.
Search for one-way flight options from Missouri to San Francisco. Find affordable one-way fares based on user searches. Data last updated maaliskuu 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/138:19 pm
STL
- SFO
1 stop29h 06m
Frontier
Deal found 3/13![Frontier logo]()
$95
This Super.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 4/238:06 pm
STL
- SFO
1 stop6h 21m
Frontier
Deal found 3/16![Frontier logo]()
$104
This Frontier deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 4/178:06 pm
STL
- SFO
1 stop6h 21m
Frontier
Deal found 3/16![Frontier logo]()
$105
This Frontier deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 4/78:43 pm
MCI
- SFO
1 stop5h 45m
Frontier
Deal found 3/15![Frontier logo]()
$105
This Super.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 4/169:55 pm
STL
- SFO
1 stop15h 33m
Frontier
Deal found 3/17![Frontier logo]()
$109
This Super.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 5/272:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Deal found 3/16![Frontier logo]()
$109
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 5/98:08 pm
STL
- SFO
1 stop17h 34m
Frontier
Deal found 3/13![Frontier logo]()
$110
This Super.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 4/172:15 pm
MCI
- SFO
1 stop12h 12m
Frontier
Deal found 3/12![Frontier logo]()
$110
This Frontier deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 5/159:18 pm
STL
- SFO
1 stop13h 12m
Frontier
Deal found 3/13![Frontier logo]()
$111
This Expedia deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to 6/42:34 pm
MCI
- SFO
1 stop11h 49m
Frontier
Deal found 3/16![Frontier logo]()
$111
This Trip.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 5/152:34 pm
MCI
- SFO
1 stop23h 08m
Frontier
Deal found 3/15![Frontier logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/68:43 pm
MCI
- SFO
1 stop25h 22m
Frontier
Deal found 3/16![Frontier logo]()
$119
Find flight deals from Missouri to San Francisco
Keep the following information in mind while searching for Missouri to San Francisco flight deals. Data was last updated maaliskuu 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $240 (Expedia) |
One-way from | $95 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $545 |
Good round-trip deal | $375 or less |
Good one-way deal | $253 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maaliskuu 17, 2026.
Use the filters below to find and compare flights from Missouri to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
ti 4/14
5:18 pm-10:55 pm
1 stop7h 37m
San Francisco
ti 4/21
12:45 pm-6:23 pm
Nonstop3h 38m
$315
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
ti 4/14
2:15 pm-11:37 pm
2 stops11h 22m
San Francisco
ti 4/21
5:59 am-7:06 pm
2 stops11h 07m
$335
ColumbiaSan Francisco
COU - SFO
COUSFO
Columbia Regional
to 4/23
4:28 pm-11:59 pm
1 stop9h 31m
San Francisco
su 4/26
12:59 am-11:35 am
1 stop8h 36m
$338
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
la 4/18
7:00 am-9:05 am
Nonstop4h 05m
San Francisco
ma 4/20
10:50 pm-8:52 am
1 stop8h 02m
$339
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
ke 4/1
2:23 pm-10:27 pm
1 stop10h 04m
San Francisco
ke 4/8
8:00 am-4:56 pm
1 stop6h 56m
$344
Quickest round-trip
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
ti 6/2
7:59 pm-9:50 pm
Nonstop3h 51m
San Francisco
to 7/30
4:29 pm-10:15 pm
Nonstop3h 46m
$349
St. LouisSan Francisco
STL - SFO
STLSFO
Lambert-St Louis
ke 4/15
8:30 am-11:13 am
Nonstop4h 43m
San Francisco
ma 4/20
11:59 pm-9:25 am
1 stop7h 26m
$358
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
pe 5/29
3:10 pm-10:10 pm
2 stops9h 00m
San Francisco
ke 7/29
11:40 am-10:00 pm
2 stops8h 20m
$359
Kansas CitySan Francisco
MCI - SFO
MCISFO
Kansas City
to 5/28
4:26 pm-8:10 pm
1 stop5h 44m
San Francisco
to 7/30
4:29 pm-10:15 pm
Nonstop3h 46m
$359
ColumbiaSan Francisco
COU - SFO
COUSFO
Columbia Regional
ti 4/7
12:06 pm-7:04 pm
2 stops8h 58m
San Francisco
pe 4/10
12:59 am-11:35 am
1 stop8h 36m
$369
Showing 1-10 of 58 resultsSorted by cheapest first
Best time to book a flight from Missouri to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Missouri with our price prediction graph.
MCI-SFO
STL-SFO
SGF-SFO
COU-SFO
JLN-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to San Francisco
USMO-SFO
MCI-SFO
STL-SFO
SGF-SFO
COU-SFO
What is the cheapest month to book a flight from Missouri to San Francisco?
Currently, June is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $119). Flying from Missouri to San Francisco in May is currently the most expensive (average of $230). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to SFO?
Find hourly flight availability from Missouri to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated maaliskuu 17, 2026.
It’s typically best to fly out from Missouri to San Francisco at noon. Doing so could potentially save you 55% on the flight price compared to flying in the evening, which is usually more expensive.
Weekly flight availability from Missouri to San Francisco
Explore weekly flight availability from Missouri to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated maaliskuu 17, 2026.
The most flights from USMO to SFO are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).
Related info for your journey
Find useful and relevant information for your journey from Missouri to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Livermore
Roseville
Watsonville
Rancho Cordova
San Bruno
San Ramon
Sunnyvale
Vacaville
San Carlos
Redwood City
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Rohnert Park
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
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Alternative routes for Missouri to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to San Francisco by cabin class
Find flights from Missouri to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and San Francisco flights
Browse other Missouri and San Francisco flight options. Last updated on maaliskuu 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on maaliskuu 17, 2026.
Missouri to San Francisco flights
Consider these flights traveling from Missouri to San Francisco.
Top 6 airlines flying from Missouri to San Francisco
Discover the top 6 airlines that operate flights from Missouri to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maaliskuu 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$122 | Average$235 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$172 | Average$332 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$176 | Average$431 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$322 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$278 | Average$425 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$284 | Average$466 | FlexibilityNo cancel fee | On-time63% |