HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Francisco

$101+ Cheap flights from Missouri to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SFO
ago. 4 — ago. 111
lun. 8/4
lun. 8/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to San Francisco

Keep the following information in mind while searching for Missouri to San Francisco flight deals. Data was last updated julio 30, 2025.

Round-trip from

$236
(Frontier)

One-way from

$101
(Hawaiian Airlines)

Popular in

December

Cheapest in

August

Average price

$307

Good round-trip deal

$470 or less

Good one-way deal

$249 or less
From Missouri to San Francisco
Search Deals
One-way flight from Missouri to San Francisco
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($18 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals
Price to beat on a round-trip flight from Missouri to San Francisco.
Search Deals
Price to beat on a one-way flight from Missouri to San Francisco.
Search Deals

Find flight deals from Missouri to San Francisco

Cheapest flights from Missouri to San Francisco
Explore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.

This Frontier deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/113:01 pmMCI - SFO
1 stop11h 15mFrontier
jue. 9/186:29 amSFO - MCI
1 stop5h 19mFrontier
Deal found 7/28$236
This Hawaiian Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Hawaiian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/103:37 pmMCI - SFO
1 stop7h 43mHawaiian Airlines
mié. 9/178:00 amSFO - MCI
1 stop6h 01mHawaiian Airlines
Deal found 7/28$245
This Alaska Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/123:37 pmMCI - SFO
1 stop8h 37mAlaska Airlines
mar. 9/166:53 pmSFO - MCI
2 stops19h 08mAlaska Airlines
Deal found 7/28$247
This FlightHub deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/125:40 pmSTL - SFO
1 stop18h 45mFrontier
jue. 8/215:45 amSFO - STL
1 stop6h 01mFrontier
Deal found 7/28$251
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/107:00 amMCI - SFO
1 stop6h 33mDelta
mar. 9/1612:45 amSFO - MCI
1 stop6h 53mDelta
Deal found 7/28$257
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/186:00 pmMCI - SFO
Nonstop4h 02mUnited Airlines
mar. 11/411:12 amSFO - MCI
Nonstop3h 25mUnited Airlines
Deal found 7/28$267
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/45:34 amMCI - SFO
1 stop7h 24mAmerican Airlines
jue. 12/411:59 pmSFO - MCI
1 stop7h 46mAmerican Airlines
Deal found 7/30$287
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/512:05 pmSGF - SFO
1 stop8h 30mAmerican Airlines
lun. 9/88:00 amSFO - SGF
1 stop8h 04mAmerican Airlines
Deal found 7/28$288
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/103:05 pmMCI - SFO
2 stops8h 20mSouthwest
mié. 9/177:00 amSFO - MCI
1 stop6h 45mSouthwest
Deal found 7/30$292
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/209:10 amSTL - SFO
Nonstop4h 10mSouthwest
mar. 8/261:45 pmSFO - STL
Nonstop3h 50mSouthwest
Deal found 7/30$293
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/265:49 pmSTL - SFO
Nonstop4h 21mUnited Airlines
mar. 9/25:15 amSFO - STL
1 stop8h 29mUnited Airlines
Deal found 7/27$303
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/2012:28 pmSTL - SFO
1 stop8h 48mAmerican Airlines
mar. 9/2312:47 amSFO - STL
1 stop10h 44mAmerican Airlines
Deal found 7/28$305

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
Use the filters below to find and compare flights from Missouri to San Francisco that are best for you.

Fly from

Missouri

Fly to

San Francisco

Route

Depart

Return

Price

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

jue. 9/11

3:01 pm-12:16 am

1 stop11h 15m

San Francisco

jue. 9/18

6:29 am-1:48 pm

1 stop5h 19m

$236

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

mié. 9/10

3:37 pm-9:20 pm

1 stop7h 43m

San Francisco

mié. 9/17

8:00 am-4:01 pm

1 stop6h 01m

$245

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

vie. 9/12

3:37 pm-10:14 pm

1 stop8h 37m

San Francisco

mar. 9/16

6:53 pm-4:01 pm

2 stops19h 08m

$247

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

mar. 8/12

5:40 pm-10:25 am

1 stop18h 45m

San Francisco

jue. 8/21

5:45 am-1:46 pm

1 stop6h 01m

$251

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

mié. 9/10

7:00 am-11:33 am

1 stop6h 33m

San Francisco

mar. 9/16

12:45 am-9:38 am

1 stop6h 53m

$257

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

sáb. 10/18

6:00 pm-8:02 pm

Nonstop4h 02m

San Francisco

mar. 11/4

11:12 am-4:37 pm

Nonstop3h 25m

$267

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

jue. 12/4

5:34 am-10:58 am

1 stop7h 24m

San Francisco

jue. 12/4

11:59 pm-9:45 am

1 stop7h 46m

$287

SpringfieldSan Francisco

SGF - SFO

SGFSFO

Springfield-Branson

vie. 9/5

12:05 pm-6:35 pm

1 stop8h 30m

San Francisco

lun. 9/8

8:00 am-6:04 pm

1 stop8h 04m

$288

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

mié. 9/10

3:05 pm-9:25 pm

2 stops8h 20m

San Francisco

mié. 9/17

7:00 am-3:45 pm

1 stop6h 45m

$292

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

mié. 8/20

9:10 am-11:20 am

Nonstop4h 10m

San Francisco

mar. 8/26

1:45 pm-7:35 pm

Nonstop3h 50m

$293

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 40 results
1
2
3
4

Best time to book a flight from Missouri to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to San Francisco

What is the cheapest month to book a flight from Missouri to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $276). Flying from Missouri to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SFO?

Find hourly flight availability from Missouri to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 30, 2025.

When flying from Missouri to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated julio 30, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Missouri to San Francisco have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Crew

8.5

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Crew

8.5

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,241 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Crew

8.5

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,980 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Crew

8.5

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Hawaiian Airlines
7.8
Good
2,611 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Crew

8.5

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,896 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Comfort

7.8

Crew

8.5

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Missouri to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Missouri?

    San Francisco (SFO) is the airport you will fly into if you book a flight from Missouri to San Francisco. It is only a 11.8 mi journey from San Francisco (SFO) to San Francisco’s city center.

  • How popular is this Missouri to San Francisco flight route?

    Flights from Missouri to San Francisco have been viewed 15 times in the past calendar month.

  • What are the cheapest airlines to fly from Missouri to San Francisco one-way?

    The cheapest airline one-way is Hawaiian Airlines, with whom users have recently found tickets for as low as $101. However, be on the lookout for offers from Frontier and Alaska Airlines, as they are both options that can get you from Missouri to San Francisco for a low price.

  • What are the most popular routes from Missouri to San Francisco?

    The most popular flight routes from Missouri to San Francisco are Kansas City - San Francisco, Lambert-St Louis - San Francisco and Springfield-Branson - San Francisco.

  • What are the most reliable airlines from Missouri to San Francisco?

    Before booking your flight to San Francisco from Missouri, check out the most reliable airlines to get you to your destination on time: Southwest (72%), United Airlines (63%), Air New Zealand( 61%).

  • What are the cheapest flights from Missouri to San Francisco?

    On average you can expect to pay $1,011 for a flight from Missouri to San Francisco. The cheapest flight overall is $180 while the most popular route, (Kansas City - San Francisco) is currently priced at $202.

  • Can I find deals for flights from Missouri to San Francisco that include hotel bookings?

    Yes. In addition to deals on Missouri to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to San Francisco.

  • Can I find deals for business class flights from Missouri to San Francisco?

    Yes. Cheapflights offers flight deals from Missouri to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $276). Flying from Missouri to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
South San Francisco
Livermore
Turlock
Manteca
Antioch
Hollister
Watsonville
Sunnyvale
Newark
Milpitas
Campbell
Foster City
Capitola
Santa Clara
San Leandro
Burlingame
Redwood City

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Dallas/Fort Worth to Las Vegas flights
Newark to Los Angeles flights
Los Angeles to Las Vegas flights
John F Kennedy Intl to San Francisco flights
Dallas/Fort Worth to Los Angeles flights
Newark to San Francisco flights
Los Angeles to San Jose flights
Hobby to Las Vegas flights
Los Angeles to San Francisco flights
O'Hare Intl to Las Vegas flights
Newark to Las Vegas flights
Ontario to San Francisco flights
Denver to Las Vegas flights
LaGuardia to Los Angeles flights
Santa Ana to Las Vegas flights
LaGuardia to Las Vegas flights
Burbank to Las Vegas flights
Santa Ana to San Francisco flights
San Francisco to Los Angeles flights
Seattle to Los Angeles flights
Seattle to Las Vegas flights
San Jose to Los Angeles flights
Dulles Intl to Las Vegas flights
Boston to Las Vegas flights
Seattle to San Francisco flights
San Francisco to Ontario flights
San Francisco to Santa Ana flights
George Bush Intcntl to Las Vegas flights
San Francisco to Las Vegas flights
Seattle to San Diego flights
Baltimore to Las Vegas flights
Boston to Los Angeles flights
Oakland to Los Angeles flights
Dallas/Fort Worth to San Francisco flights
LaGuardia to San Francisco flights
O'Hare Intl to Los Angeles flights
San Jose to Las Vegas flights
Reagan-National to Los Angeles flights
Atlanta to Las Vegas flights
John F Kennedy Intl to Ontario flights
Fort Lauderdale to Las Vegas flights
O'Hare Intl to San Francisco flights
Santa Ana to Oakland flights
Oakland to Las Vegas flights
Newark to Burbank flights
Newark to San Diego flights
John F Kennedy Intl to San Diego flights
Dulles Intl to Los Angeles flights

Top 6 airlines flying from Missouri to San Francisco

Discover the top 6 airlines that operate flights from Missouri to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$77Average$215FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$198Average$408FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$326FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$242Average$478FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$278Average$417FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$308Average$435FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.