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$109+ Cheap flights from Missouri to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SFO
ago. 12 — ago. 191
mar. 8/12
mar. 8/19
1 adult, Economy
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Cheap flight deals from Missouri to San Francisco

Keep the following information in mind while searching for Missouri to San Francisco flight deals. Data was last updated agosto 7, 2025.

Round-trip from

$219
(American Airlines)

One-way from

$109
(CheapOair)

Popular in

December

Cheapest in

August

Average price

$301

Good round-trip deal

$482 or less

Good one-way deal

$249 or less
From Missouri to San Francisco
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One-way flight from Missouri to San Francisco
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Highest demand for flights based on searches. 4% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Missouri to San Francisco.
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Price to beat on a one-way flight from Missouri to San Francisco.
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Find flight deals from Missouri to San Francisco

Cheapest flights from Missouri to San Francisco
Explore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 7, 2025.

This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/107:56 amMCI - SFO
1 stop10h 07mAmerican Airlines
mié. 9/175:50 amSFO - MCI
1 stop9h 18mAmerican Airlines
Deal found 8/7$219
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/85:59 pmMCI - SFO
1 stop6h 52mDelta
vie. 9/124:55 pmSFO - MCI
1 stop5h 09mDelta
Deal found 8/7$237
This Frontier deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/242:18 pmMCI - SFO
1 stop12h 01mFrontier
jue. 8/286:26 amSFO - MCI
1 stop5h 07mFrontier
Deal found 8/7$243
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/244:40 pmSTL - SFO
1 stop6h 23mUnited Airlines
lun. 9/2912:43 amSFO - STL
1 stop7h 09mUnited Airlines
Deal found 8/7$252
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/172:27 pmSTL - SFO
1 stop19h 14mFrontier
lun. 8/258:51 amSFO - STL
1 stop22h 20mFrontier
Deal found 8/7$255
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/266:40 amSTL - SFO
1 stop9h 47mDelta
jue. 10/212:45 amSFO - STL
1 stop8h 45mDelta
Deal found 8/7$257
This Frontier deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/287:55 pmSTL - SFO
1 stop6h 21mFrontier
vie. 10/108:04 pmSFO - STL
1 stop11h 03mFrontier
Deal found 8/5$258
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/236:03 pmMCI - SFO
1 stop7h 47mDelta
lun. 10/612:50 amSFO - MCI
1 stop8h 46mDelta
Deal found 8/7$258
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/294:40 pmSTL - SFO
1 stop6h 23mUnited Airlines
dom. 8/3112:43 amSFO - STL
1 stop7h 18mUnited Airlines
Deal found 8/7$259
This Gotogate deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/297:54 pmSTL - SFO
1 stop28h 39mFrontier
lun. 9/16:26 amSFO - STL
1 stop24h 45mFrontier
Deal found 8/7$260
This Justfly.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/55:44 pmSTL - SFO
1 stop23h 57mFrontier
dom. 12/77:53 pmSFO - STL
1 stop12h 09mFrontier
Deal found 8/7$261
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/153:01 pmMCI - SFO
1 stop11h 15mFrontier
sáb. 9/2010:49 amSFO - MCI
1 stop24h 59mFrontier
Deal found 8/7$261

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 7, 2025.
Use the filters below to find and compare flights from Missouri to San Francisco that are best for you.

Fly from

Missouri

Fly to

San Francisco

Route

Depart

Return

Price

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

mié. 9/10

7:56 am-4:03 pm

1 stop10h 07m

San Francisco

mié. 9/17

5:50 am-5:08 pm

1 stop9h 18m

$219

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

lun. 9/8

5:59 pm-10:51 pm

1 stop6h 52m

San Francisco

vie. 9/12

4:55 pm-12:04 am

1 stop5h 09m

$237

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

dom. 8/24

2:18 pm-12:19 am

1 stop12h 01m

San Francisco

jue. 8/28

6:26 am-1:33 pm

1 stop5h 07m

$243

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

mié. 9/24

4:40 pm-9:03 pm

1 stop6h 23m

San Francisco

lun. 9/29

12:43 am-9:52 am

1 stop7h 09m

$252

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

dom. 8/17

2:27 pm-7:41 am

1 stop19h 14m

San Francisco

lun. 8/25

8:51 am-9:11 am

1 stop22h 20m

$255

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

vie. 9/26

6:40 am-2:27 pm

1 stop9h 47m

San Francisco

jue. 10/2

12:45 am-11:30 am

1 stop8h 45m

$257

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

dom. 9/28

7:55 pm-12:16 am

1 stop6h 21m

San Francisco

vie. 10/10

8:04 pm-9:07 am

1 stop11h 03m

$258

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

mar. 9/23

6:03 pm-11:50 pm

1 stop7h 47m

San Francisco

lun. 10/6

12:50 am-11:36 am

1 stop8h 46m

$258

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

vie. 8/29

4:40 pm-9:03 pm

1 stop6h 23m

San Francisco

dom. 8/31

12:43 am-10:01 am

1 stop7h 18m

$259

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

vie. 8/29

7:54 pm-10:33 pm

1 stop28h 39m

San Francisco

lun. 9/1

6:26 am-9:11 am

1 stop24h 45m

$260

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/6

Showing 1-10 of 57 results
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Best time to book a flight from Missouri to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to San Francisco

What is the cheapest month to book a flight from Missouri to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $276). Flying from Missouri to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SFO?

Find hourly flight availability from Missouri to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 7, 2025.

When flying from Missouri to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated agosto 7, 2025.
See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Missouri to San Francisco have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOI - LAX

flying in first class, my husband froze the entire flight and was miserable. first class does not offer blankets or any entertainment. (TV etc)
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOI - LAX

flying in first class, my husband froze the entire flight and was miserable. first class does not offer blankets or any entertainment. (TV etc)
Southwest
8.0
Very good
4,247 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOI - LAX

flying in first class, my husband froze the entire flight and was miserable. first class does not offer blankets or any entertainment. (TV etc)
Delta
8.0
Very good
7,987 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOI - LAX

flying in first class, my husband froze the entire flight and was miserable. first class does not offer blankets or any entertainment. (TV etc)
United Airlines
7.4
Good
8,916 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOI - LAX

flying in first class, my husband froze the entire flight and was miserable. first class does not offer blankets or any entertainment. (TV etc)
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Entertainment

7.1

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

BOI - LAX

flying in first class, my husband froze the entire flight and was miserable. first class does not offer blankets or any entertainment. (TV etc)

Related info for your journey

Find useful and relevant information for your journey from Missouri to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Missouri?

    San Francisco (SFO) is the airport you will fly into if you book a flight from Missouri to San Francisco. It is only a 11.8 mi journey from San Francisco (SFO) to San Francisco’s city center.

  • How popular is this Missouri to San Francisco flight route?

    Flights from Missouri to San Francisco have been viewed 16 times in the past calendar month.

  • What are the most popular routes from Missouri to San Francisco?

    The most popular flight routes from Missouri to San Francisco are Kansas City - San Francisco, Lambert-St Louis - San Francisco and Springfield-Branson - San Francisco.

  • What are the most reliable airlines from Missouri to San Francisco?

    Before booking your flight to San Francisco from Missouri, check out the most reliable airlines to get you to your destination on time: Southwest (79%), Air New Zealand (59%), Asiana Airlines( 55%).

  • What are the cheapest flights from Missouri to San Francisco?

    On average you can expect to pay $780 for a flight from Missouri to San Francisco. The cheapest flight overall is $205 while the most popular route, (Kansas City - San Francisco) is currently priced at $232.

  • Can I find deals for flights from Missouri to San Francisco that include hotel bookings?

    Yes. In addition to deals on Missouri to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to San Francisco.

  • Can I find deals for business class flights from Missouri to San Francisco?

    Yes. Cheapflights offers flight deals from Missouri to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $276). Flying from Missouri to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Livermore
South San Francisco
Turlock
Hollister
Antioch
Watsonville
Manteca
Sunnyvale
Newark
Milpitas
Santa Clara
Campbell
Foster City
San Leandro
Burlingame
Redwood City
Vallejo

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Alternative routes for Missouri to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Missouri to San Francisco

Discover the top 6 airlines that operate flights from Missouri to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 7, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$221FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$198Average$408FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$326FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$242Average$478FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$278Average$417FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$308Average$435FlexibilityNo cancel feeOn-time63%

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