$170+ Cheap flights from Greenville to San Francisco (GSP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/2. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SFO
Jun 21 — Jun 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Greenville to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:25 am
GSP
- SFO
1 stop7h 17m
Delta
Tue 8/1811:42 am
SFO
- GSP
1 stop6h 44m
Delta
Deal found 5/17![Delta logo]()
$395
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:50 pm
GSP
- SFO
1 stop9h 00m
Southwest
Tue 6/235:30 am
SFO
- GSP
2 stops10h 30m
Southwest
Deal found 5/18![Southwest logo]()
$400
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:50 pm
GSP
- SFO
2 stops10h 05m
Southwest
Wed 7/1510:50 pm
SFO
- GSP
1 stop10h 25m
Southwest
Deal found 5/19![Southwest logo]()
$406
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:10 am
GSP
- SFO
1 stop10h 03m
Delta
Mon 8/176:00 am
SFO
- GSP
1 stop7h 15m
Delta
Deal found 5/17![Delta logo]()
$408
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:55 pm
GSP
- SFO
1 stop7h 53m
American Airlines
Tue 6/235:23 am
SFO
- GSP
1 stop8h 09m
American Airlines
Deal found 5/17![American Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:00 am
GSP
- SFO
1 stop8h 25m
Southwest
Mon 8/105:10 am
SFO
- GSP
2 stops10h 10m
Southwest
Deal found 5/20![Southwest logo]()
$413
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:05 pm
GSP
- SFO
2 stops12h 50m
Southwest
Mon 8/1010:30 pm
SFO
- GSP
1 stop8h 45m
Southwest
Deal found 5/21![Southwest logo]()
$414
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:54 am
GSP
- SFO
1 stop9h 48m
Delta
Thu 9/1011:45 pm
SFO
- GSP
1 stop6h 42m
Delta
Deal found 5/20![Delta logo]()
$421
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:44 pm
GSP
- SFO
1 stop7h 52m
Delta
Wed 8/127:53 am
SFO
- GSP
1 stop9h 39m
Delta
Deal found 5/17![Delta logo]()
$431
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:55 pm
GSP
- SFO
2 stops14h 35m
Southwest
Mon 10/1211:40 pm
SFO
- GSP
2 stops9h 30m
Southwest
Deal found 5/17![Southwest logo]()
$437
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/191:09 pm
GSP
- SFO
1 stop7h 22m
Delta
Tue 7/2111:59 pm
SFO
- GSP
1 stop7h 48m
Delta
Deal found 5/19![Delta logo]()
$431
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:00 am
GSP
- SFO
2 stops10h 15m
Southwest
Sun 9/66:35 am
SFO
- GSP
2 stops11h 50m
Southwest
Deal found 5/21![Southwest logo]()
$441
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:16 pm
GSP
- SFO
1 stop7h 32m
Delta
Sat 8/810:00 pm
SFO
- GSP
1 stop8h 18m
Delta
Deal found 5/17![Delta logo]()
$444
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:05 am
GSP
- SFO
2 stops10h 20m
Southwest
Mon 8/1010:30 pm
SFO
- GSP
1 stop8h 45m
Southwest
Deal found 5/17![Southwest logo]()
$449
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:50 pm
GSP
- SFO
1 stop9h 00m
Southwest
Sat 7/45:20 am
SFO
- GSP
2 stops10h 50m
Southwest
Deal found 5/17![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:05 am
GSP
- SFO
2 stops8h 55m
Southwest
Sun 7/1911:40 pm
SFO
- GSP
2 stops9h 35m
Southwest
Deal found 5/21![Southwest logo]()
$477
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:50 pm
GSP
- SFO
2 stops8h 40m
Southwest
Fri 7/1710:50 pm
SFO
- GSP
1 stop10h 25m
Southwest
Deal found 5/21![Southwest logo]()
$478
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:50 pm
GSP
- SFO
2 stops8h 40m
Southwest
Sat 7/410:45 pm
SFO
- GSP
1 stop10h 25m
Southwest
Deal found 5/17![Southwest logo]()
$478
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:05 am
GSP
- SFO
2 stops10h 20m
Southwest
Sun 6/2110:50 pm
SFO
- GSP
1 stop10h 25m
Southwest
Deal found 5/18![Southwest logo]()
$500
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated May 22, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated May 22, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:50 pm
GSP
- SFO
1 stop9h 00m
Southwest
Tue 6/235:30 am
SFO
- GSP
2 stops10h 30m
Southwest
Deal found 5/18![Southwest logo]()
$400
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:55 pm
GSP
- SFO
1 stop7h 53m
American Airlines
Tue 6/235:23 am
SFO
- GSP
1 stop8h 09m
American Airlines
Deal found 5/17![American Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:00 am
GSP
- SFO
2 stops11h 00m
Southwest
Wed 6/248:55 am
SFO
- GSP
2 stops10h 05m
Southwest
Deal found 5/18![Southwest logo]()
$447
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/291:09 pm
GSP
- SFO
1 stop6h 58m
Delta
Sat 7/47:50 am
SFO
- GSP
1 stop8h 26m
Delta
Deal found 5/18![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:50 pm
GSP
- SFO
2 stops8h 40m
Southwest
Sat 7/45:20 am
SFO
- GSP
2 stops10h 50m
Southwest
Deal found 5/18![Southwest logo]()
$477
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:16 pm
GSP
- SFO
1 stop8h 33m
Delta
Tue 7/146:00 am
SFO
- GSP
1 stop7h 07m
Delta
Deal found 5/19![Delta logo]()
$395
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:16 pm
GSP
- SFO
1 stop8h 33m
Delta
Thu 7/1610:59 pm
SFO
- GSP
1 stop8h 48m
Delta
Deal found 5/19![Delta logo]()
$431
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:52 am
GSP
- SFO
2 stops13h 03m
Delta
Wed 7/1510:59 pm
SFO
- GSP
1 stop8h 48m
Delta
Deal found 5/19![Delta logo]()
$453
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:50 pm
GSP
- SFO
1 stop9h 00m
Southwest
Sat 7/45:20 am
SFO
- GSP
2 stops10h 50m
Southwest
Deal found 5/17![Southwest logo]()
$472
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:44 am
GSP
- SFO
1 stop7h 43m
Delta
Sat 7/47:50 am
SFO
- GSP
1 stop9h 30m
Delta
Deal found 5/17![Delta logo]()
$473
One-way flights from Greenville to San FranciscoSearch for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
Search for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:37 am
GSP
- SFO
3 stops58h 44m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:03 am
GSP
- SFO
1 stop13h 57m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:25 pm
GSP
- SFO
1 stop8h 05m
American Airlines
Deal found 5/21![American Airlines logo]()
$198
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:00 am
GSP
- SFO
2 stops11h 00m
Southwest
Deal found 5/21![Southwest logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/298:24 am
GSP
- SFO
2 stops29h 04m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:20 am
GSP
- SFO
3 stops39h 10m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:25 pm
GSP
- SFO
1 stop8h 05m
American Airlines
Deal found 5/21![American Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:50 pm
GSP
- SFO
2 stops8h 40m
Southwest
Deal found 5/20![Southwest logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/288:19 am
GSP
- SFO
2 stops53h 09m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$241
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $395 (Delta) |
One-way from | $170 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $585 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Fri 7/31
7:44 pm-12:36 am
1 stop7h 52m
San Francisco
Wed 8/12
7:53 am-8:32 pm
1 stop9h 39m
$431
Quickest round-trip
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Sun 7/19
1:09 pm-5:31 pm
1 stop7h 22m
San Francisco
Tue 7/21
11:59 pm-10:47 am
1 stop7h 48m
$431
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Thu 10/8
12:55 pm-12:30 am
2 stops14h 35m
San Francisco
Mon 10/12
11:40 pm-12:10 pm
2 stops9h 30m
$437
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Wed 9/2
11:00 am-6:15 pm
2 stops10h 15m
San Francisco
Sun 9/6
6:35 am-9:25 pm
2 stops11h 50m
$441
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Fri 7/31
5:16 pm-9:48 pm
1 stop7h 32m
San Francisco
Sat 8/8
10:00 pm-9:18 am
1 stop8h 18m
$444
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Fri 7/31
7:05 am-2:25 pm
2 stops10h 20m
San Francisco
Mon 8/10
10:30 pm-10:15 am
1 stop8h 45m
$449
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Tue 6/30
1:50 pm-7:50 pm
1 stop9h 00m
San Francisco
Sat 7/4
5:20 am-7:10 pm
2 stops10h 50m
$472
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Thu 7/2
7:05 am-1:00 pm
2 stops8h 55m
San Francisco
Sun 7/19
11:40 pm-12:15 pm
2 stops9h 35m
$477
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Mon 7/13
6:50 pm-12:30 am
2 stops8h 40m
San Francisco
Fri 7/17
10:50 pm-12:15 pm
1 stop10h 25m
$478
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Mon 6/29
6:50 pm-12:30 am
2 stops8h 40m
San Francisco
Sat 7/4
10:45 pm-12:10 pm
1 stop10h 25m
$478
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Francisco in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Greenville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
GSP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Francisco
How far ahead should I book a flight from Greenville to San Francisco?
The price you pay for your flight from Greenville to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 71 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Francisco?
Currently, August is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $412). Flying from Greenville to San Francisco in January is currently the most expensive (average of $668). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 22, 2026.
Read through reviews of airlines operating flights from Greenville to San Francisco, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
Vallejo
San Lorenzo
Davis
Emeryville
Manteca
Elk Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Greenville
Popular flights
San Francisco flight routes
Alternative routes for Greenville to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to San Francisco by cabin class
Find flights from Greenville to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and San Francisco flights
Browse other Greenville and San Francisco flight options. Last updated on May 22, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on May 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 22, 2026.
Top 4 airlines flying from Greenville to San Francisco
Discover the top 4 airlines that operate flights from Greenville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$514 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$311 | Average$520 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$330 | Average$512 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$332 | Average$528 | FlexibilityNo cancel fee | On-time71% |