$184+ Cheap flights from Greenville to San Francisco (GSP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/11. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SFO
Mar 26 — Apr 21
1 adult, Economy
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Find cheap flights from Greenville to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Francisco
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Best
Last-minute
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Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 24, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 24, 2026.
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:28 pm
GSP
- SFO
1 stop8h 00m
American Airlines
Mon 4/131:16 pm
SFO
- GSP
1 stop7h 41m
American Airlines
Deal found 2/23![American Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:25 pm
GSP
- SFO
2 stops8h 55m
Southwest
Wed 4/155:25 am
SFO
- GSP
2 stops11h 35m
Southwest
Deal found 2/23![Southwest logo]()
$358
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:55 pm
GSP
- SFO
1 stop10h 04m
United Airlines
Tue 3/2411:59 pm
SFO
- GSP
1 stop7h 02m
United Airlines
Deal found 2/20![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/181:50 pm
GSP
- SFO
1 stop11h 15m
Southwest
Tue 3/2411:25 pm
SFO
- GSP
2 stops10h 50m
Southwest
Deal found 2/20![Southwest logo]()
$372
This Southwest deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:50 pm
GSP
- SFO
1 stop12h 30m
Southwest
Mon 4/2711:25 pm
SFO
- GSP
2 stops10h 45m
Southwest
Deal found 2/23![Southwest logo]()
$378
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:50 pm
GSP
- SFO
1 stop11h 15m
Southwest
Mon 3/2311:25 pm
SFO
- GSP
2 stops10h 50m
Southwest
Deal found 2/22![Southwest logo]()
$385
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:28 pm
GSP
- SFO
1 stop9h 47m
American Airlines
Sat 5/212:30 am
SFO
- GSP
1 stop8h 49m
American Airlines
Deal found 2/23![American Airlines logo]()
$387
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:32 pm
GSP
- SFO
1 stop9h 44m
United Airlines
Mon 3/309:30 pm
SFO
- GSP
1 stop9h 25m
United Airlines
Deal found 2/23![United Airlines logo]()
$393
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 24, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 24, 2026.
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:55 pm
GSP
- SFO
1 stop10h 04m
United Airlines
Tue 3/2411:59 pm
SFO
- GSP
1 stop7h 02m
United Airlines
Deal found 2/20![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:50 pm
GSP
- SFO
1 stop12h 30m
Southwest
Mon 4/2711:25 pm
SFO
- GSP
2 stops10h 45m
Southwest
Deal found 2/23![Southwest logo]()
$378
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:43 am
GSP
- SFO
1 stop9h 06m
Delta
Thu 6/1111:45 pm
SFO
- GSP
1 stop7h 43m
Delta
Deal found 2/23![Delta logo]()
$447
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:36 pm
GSP
- SFO
1 stop9h 48m
United Airlines
Sun 4/2612:45 am
SFO
- GSP
1 stop8h 09m
United Airlines
Deal found 2/23![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Sun 4/2611:25 pm
SFO
- GSP
2 stops10h 50m
Southwest
Deal found 2/21![Southwest logo]()
$412
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:36 pm
GSP
- SFO
1 stop8h 04m
United Airlines
Sat 5/236:05 am
SFO
- GSP
1 stop7h 55m
United Airlines
Deal found 2/21![United Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:00 am
GSP
- SFO
1 stop9h 25m
Southwest
Sat 5/2311:25 pm
SFO
- GSP
2 stops10h 55m
Southwest
Deal found 2/21![Southwest logo]()
$417
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:10 pm
GSP
- SFO
1 stop9h 45m
United Airlines
Sun 4/265:00 am
SFO
- GSP
1 stop7h 09m
United Airlines
Deal found 2/21![United Airlines logo]()
$420
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:00 am
GSP
- SFO
2 stops11h 00m
Southwest
Wed 7/2911:40 pm
SFO
- GSP
2 stops9h 35m
Southwest
Deal found 2/20![Southwest logo]()
$457
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/161:55 pm
GSP
- SFO
1 stop12h 45m
Southwest
Sun 3/2210:55 pm
SFO
- GSP
1 stop9h 50m
Southwest
Deal found 2/20![Southwest logo]()
$467
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated February 24, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated February 24, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:50 pm
GSP
- SFO
1 stop11h 15m
Southwest
Mon 3/2311:25 pm
SFO
- GSP
2 stops10h 50m
Southwest
Deal found 2/22![Southwest logo]()
$385
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:14 pm
GSP
- SFO
2 stops16h 40m
Delta
Tue 3/245:50 am
SFO
- GSP
1 stop8h 39m
Delta
Deal found 2/24![Delta logo]()
$405
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:50 pm
GSP
- SFO
1 stop11h 15m
Southwest
Sun 3/2210:55 pm
SFO
- GSP
1 stop9h 50m
Southwest
Deal found 2/22![Southwest logo]()
$448
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:55 pm
GSP
- SFO
1 stop10h 04m
United Airlines
Tue 3/2411:59 pm
SFO
- GSP
1 stop7h 02m
United Airlines
Deal found 2/20![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/181:50 pm
GSP
- SFO
1 stop11h 15m
Southwest
Tue 3/2411:25 pm
SFO
- GSP
2 stops10h 50m
Southwest
Deal found 2/20![Southwest logo]()
$372
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:41 pm
GSP
- SFO
1 stop9h 54m
Delta
Tue 3/245:50 am
SFO
- GSP
1 stop8h 39m
Delta
Deal found 2/24![Delta logo]()
$380
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:32 pm
GSP
- SFO
1 stop9h 44m
United Airlines
Mon 3/309:30 pm
SFO
- GSP
1 stop9h 25m
United Airlines
Deal found 2/23![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:25 am
GSP
- SFO
2 stops11h 05m
Southwest
Mon 3/3011:25 pm
SFO
- GSP
2 stops9h 35m
Southwest
Deal found 2/23![Southwest logo]()
$403
One-way flights from Greenville to San FranciscoSearch for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated February 24, 2026.
Search for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated February 24, 2026.
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:42 pm
GSP
- SFO
1 stop8h 35m
United Airlines
Deal found 2/23![United Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:12 pm
GSP
- SFO
2 stops35h 19m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$185
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:20 am
GSP
- SFO
1 stop9h 56m
American Airlines
Deal found 2/20![American Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/109:33 am
GSP
- SFO
2 stops34h 19m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$191
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:25 am
GSP
- SFO
2 stops12h 00m
Southwest
Deal found 2/21![Southwest logo]()
$194
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:12 pm
GSP
- SFO
1 stop9h 42m
American Airlines
Deal found 2/23![American Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:03 am
GSP
- SFO
1 stop12h 07m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$208
This Southwest deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:25 pm
GSP
- SFO
2 stops8h 55m
Southwest
Deal found 2/23![Southwest logo]()
$209
This American Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:35 pm
GSP
- SFO
1 stop10h 27m
American Airlines
Deal found 2/23![American Airlines logo]()
$224
This Southwest deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:00 am
GSP
- SFO
2 stops10h 10m
Southwest
Deal found 2/23![Southwest logo]()
$229
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:10 pm
GSP
- SFO
1 stop9h 45m
United Airlines
Deal found 2/23![United Airlines logo]()
$234
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $347 (American Airlines) |
One-way from | $184 (United Airlines) |
Popular in | January |
Cheapest in | August |
Average price | $623 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Greenville
Fly to
San Francisco
Route
Depart
Return
Price
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Wed 3/18
4:55 pm-11:59 pm
1 stop10h 04m
San Francisco
Tue 3/24
11:59 pm-10:01 am
1 stop7h 02m
$367
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Thu 4/23
5:36 pm-12:24 am
1 stop9h 48m
San Francisco
Sun 4/26
12:45 am-11:54 am
1 stop8h 09m
$367
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Thu 4/23
1:50 pm-11:20 pm
1 stop12h 30m
San Francisco
Mon 4/27
11:25 pm-1:10 pm
2 stops10h 45m
$378
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Wed 4/22
1:55 pm-9:25 pm
1 stop10h 30m
San Francisco
Sun 4/26
11:25 pm-1:15 pm
2 stops10h 50m
$412
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Sat 4/25
5:36 pm-10:40 pm
1 stop8h 04m
San Francisco
Sat 5/23
6:05 am-5:00 pm
1 stop7h 55m
$412
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Sat 4/25
8:00 am-2:25 pm
1 stop9h 25m
San Francisco
Sat 5/23
11:25 pm-1:20 pm
2 stops10h 55m
$417
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Thu 4/23
4:10 pm-10:55 pm
1 stop9h 45m
San Francisco
Sun 4/26
5:00 am-3:09 pm
1 stop7h 09m
$420
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Wed 5/27
11:43 am-5:49 pm
1 stop9h 06m
San Francisco
Thu 6/11
11:45 pm-10:28 am
1 stop7h 43m
$447
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Tue 7/21
7:00 am-3:00 pm
2 stops11h 00m
San Francisco
Wed 7/29
11:40 pm-12:15 pm
2 stops9h 35m
$457
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Mon 3/16
1:55 pm-11:40 pm
1 stop12h 45m
San Francisco
Sun 3/22
10:55 pm-11:45 am
1 stop9h 50m
$467
Showing 1-10 of 19 results
Compare providers for flights from Greenville to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Francisco in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Greenville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
GSP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Francisco
How far ahead should I book a flight from Greenville to San Francisco?
Use this chart to determine the optimal time to book a round-trip flight from Greenville to San Francisco. Price data was last updated on February 20, 2026.
The price you pay for your flight from Greenville to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 72 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Francisco?
Currently, August is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $106). Flying from Greenville to San Francisco in December is currently the most expensive (average of $338). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated February 24, 2026.
Read through reviews of airlines operating flights from Greenville to San Francisco, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santa Cruz
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Davis
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Greenville and San Francisco flights
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Top 4 airlines flying from Greenville to San Francisco
Discover the top 4 airlines that operate flights from Greenville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$462 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$311 | Average$466 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$330 | Average$457 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$332 | Average$490 | FlexibilityNo cancel fee | On-time71% |