$169+ Cheap flights from Greenville to San Francisco (GSP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SFO
Sep 29 — Oct 61
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Francisco
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Best
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One-way
Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 30, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 30, 2026.
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:25 pm -
1 stop7h 40m
Tue 12/86:00 am -
1 stop6h 45m
Deal found 8/27![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:20 am -
1 stop7h 30m
Mon 12/78:00 am -
2 stops9h 45m
Deal found 8/27![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:20 am -
2 stops10h 25m
Tue 12/86:10 am -
2 stops9h 00m
Deal found 8/27![Southwest logo]()
$347
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:05 pm -
2 stops10h 30m
Wed 9/1611:05 pm -
1 stop10h 25m
Deal found 8/26![Southwest logo]()
$348
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:45 pm -
1 stop7h 59m
Fri 10/3010:03 pm -
1 stop7h 21m
Deal found 8/27![American Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Thu 10/298:25 am -
1 stop9h 10m
Fri 10/309:35 am -
2 stops10h 15m
Deal found 8/27![Southwest logo]()
$358
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:40 am -
1 stop7h 54m
Mon 10/2611:30 pm -
1 stop6h 53m
Deal found 8/26![Delta logo]()
$378
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:25 am -
2 stops9h 55m
Mon 10/511:40 pm -
2 stops10h 00m
Deal found 8/26![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:25 am -
2 stops9h 55m
Tue 10/139:35 pm -
1 stop9h 30m
Deal found 8/27![Southwest logo]()
$397
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 30, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 30, 2026.
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/157:50 am -
1 stop9h 10m
Sat 1/2311:50 pm -
2 stops9h 55m
Deal found 8/26![Southwest logo]()
$374
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:25 pm -
1 stop8h 32m
Tue 10/610:25 pm -
1 stop7h 58m
Deal found 8/30![Delta logo]()
$423
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:10 pm -
1 stop19h 51m
Sat 9/1911:58 pm -
2 stops35h 30m
Deal found 8/30![Multiple Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:47 pm -
1 stop8h 12m
Thu 9/175:00 am -
1 stop7h 14m
Deal found 8/26![United Airlines logo]()
$594
This Alaska Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:11 pm -
2 stops12h 01m
Tue 9/295:16 pm -
2 stops21h 37m
Deal found 8/27![Alaska Airlines logo]()
$700
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:45 am -
1 stop9h 15m
Wed 10/711:30 pm -
1 stop6h 53m
Deal found 8/26![Delta logo]()
$428
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:20 am -
2 stops10h 20m
Fri 11/2712:10 pm -
1 stop7h 45m
Deal found 8/28![Southwest logo]()
$428
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:55 pm -
2 stops10h 25m
Thu 11/2611:30 pm -
2 stops17h 40m
Deal found 8/28![Southwest logo]()
$445
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:05 pm -
2 stops9h 10m
Tue 9/1510:30 pm -
1 stop8h 45m
Deal found 8/27![Southwest logo]()
$472
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:35 pm -
1 stop8h 24m
Tue 9/296:45 pm -
2 stops17h 23m
Deal found 8/29![United Airlines logo]()
$634
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:45 am -
2 stops9h 55m
Sun 12/275:25 am -
2 stops11h 00m
Deal found 8/28![Southwest logo]()
$667
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated August 30, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated August 30, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:00 am -
1 stop11h 04m
Fri 9/115:00 am -
1 stop7h 14m
Deal found 8/29![United Airlines logo]()
$420
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:05 pm -
2 stops10h 30m
Wed 9/166:50 am -
2 stops11h 10m
Deal found 8/26![Southwest logo]()
$347
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:15 am -
1 stop9h 51m
Sat 9/2610:59 pm -
1 stop8h 25m
Deal found 8/26![Delta logo]()
$378
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:04 am -
1 stop10h 05m
Thu 9/246:23 am -
2 stops12h 03m
Deal found 8/26![Delta logo]()
$411
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:24 pm -
1 stop9h 56m
Tue 9/298:09 am -
1 stop7h 50m
Deal found 8/27![American Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:46 pm -
1 stop7h 34m
Sun 9/2710:46 pm -
1 stop9h 17m
Deal found 8/26![American Airlines logo]()
$407
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:24 pm -
1 stop9h 56m
Thu 10/15:30 am -
1 stop8h 04m
Deal found 8/27![American Airlines logo]()
$422
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:05 pm -
2 stops9h 10m
Sun 9/277:50 am -
2 stops11h 55m
Deal found 8/26![Southwest logo]()
$433
This Southwest deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:45 am -
2 stops11h 00m
Sat 10/310:35 am -
1 stop7h 00m
Deal found 8/29![Southwest logo]()
$428
One-way flights from Greenville to San FranciscoSearch for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 30, 2026.
Search for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 30, 2026.
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/165:23 pm -
1 stop9h 05m
Deal found 8/27![American Airlines logo]()
$169
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am -
2 stops8h 35m
Deal found 8/26![Southwest logo]()
$174
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:25 pm -
1 stop8h 32m
Deal found 8/26![Delta logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 pm -
3 stops32h 14m
Deal found 8/27![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:10 pm -
2 stops22h 19m
Deal found 8/26![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:28 am -
3 stops36h 04m
Deal found 8/27![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:32 pm -
3 stops47h 31m
Deal found 8/28![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:29 pm -
3 stops58h 19m
Deal found 8/26![Multiple Airlines logo]()
$205
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:00 pm -
1 stop9h 57m
Deal found 8/26![Delta logo]()
$210
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $337 (American Airlines) |
One-way from | $169 (Delta) |
Popular in | January |
Cheapest in | November |
Average price | $493 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 30, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Fri 1/15
7:50 am-2:00 pm
1 stop9h 10m
San Francisco
Sat 1/23
11:50 pm-12:45 pm
2 stops9h 55m
$374
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Thu 10/1
6:25 pm-11:57 pm
1 stop8h 32m
San Francisco
Tue 10/6
10:25 pm-9:23 am
1 stop7h 58m
$423
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Sun 10/4
5:45 am-12:00 pm
1 stop9h 15m
San Francisco
Wed 10/7
11:30 pm-9:23 am
1 stop6h 53m
$428
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Sat 11/21
6:20 am-1:40 pm
2 stops10h 20m
San Francisco
Fri 11/27
12:10 pm-10:55 pm
1 stop7h 45m
$428
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Sat 11/21
4:55 pm-12:20 am
2 stops10h 25m
San Francisco
Thu 11/26
11:30 pm-8:10 pm
2 stops17h 40m
$445
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Fri 9/11
1:05 pm-7:15 pm
2 stops9h 10m
San Francisco
Tue 9/15
10:30 pm-10:15 am
1 stop8h 45m
$472
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Mon 9/14
7:10 pm-12:01 pm
1 stop19h 51m
San Francisco
Sat 9/19
11:58 pm-2:28 pm
2 stops35h 30m
$489
Quickest round-trip
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Mon 9/14
7:47 pm-12:59 am
1 stop8h 12m
San Francisco
Thu 9/17
5:00 am-3:14 pm
1 stop7h 14m
$594
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Thu 9/24
7:35 pm-12:59 am
1 stop8h 24m
San Francisco
Tue 9/29
6:45 pm-3:08 pm
2 stops17h 23m
$634
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Wed 12/23
6:45 am-1:40 pm
2 stops9h 55m
San Francisco
Sun 12/27
5:25 am-7:25 pm
2 stops11h 00m
$667
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Francisco in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Greenville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
GSP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Francisco
How far ahead should I book a flight from Greenville to San Francisco?
The price you pay for your flight from Greenville to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Francisco?
Currently, November is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $462). Flying from Greenville to San Francisco in January is currently the most expensive (average of $685). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Francisco?
Airfare is below average for this route at the moment.
Greenville to San Francisco flights typically cost between $340 and $697 in December.The cheapest round-trip price found within the last 5 days was $337 on Delta (Dec 3-Dec 7).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated August 30, 2026.
Read through reviews of airlines operating flights from Greenville to San Francisco, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Emeryville
San Bruno
Burlingame
Rancho Cordova
Roseville
Fairfield
Vallejo
Cupertino
Newark
Hayward
San Ramon
Redwood City
Manteca
San Carlos
Turlock
Davis
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Find flights from Greenville to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and San Francisco flights
Browse other Greenville and San Francisco flight options. Last updated on August 30, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on August 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 30, 2026.
Top 4 airlines flying from Greenville to San Francisco
Discover the top 4 airlines that operate flights from Greenville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$311 | Average$520 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$340 | Average$546 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$362 | Average$547 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$402 | Average$503 | FlexibilityNo cancel fee | On-time63% |