San Francisco

$149+ Cheap flights from Greenville to San Francisco (GSP - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SFO
Jun 17 — Jun 241
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Cheapflights Tip: The best prices from Greenville to San Francisco are usually found in January or August, booked 77 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Greenville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$297
(United Airlines)

One-way from

$149
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$453
From Greenville to San Francisco
One-way flight from Greenville to San Francisco
Highest demand for flights based on searches. 8% potential increase in price ($44 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Average for round-trip flights in June 2025

Find flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1010:15 amGSP - SFO
1 stop8h 08mUnited Airlines
Mon 9/159:15 pmSFO - GSP
1 stop8h 36mUnited Airlines
Deal found 6/9$297
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/109:30 amGSP - SFO
2 stops11h 55mSouthwest
Mon 9/159:05 pmSFO - GSP
1 stop9h 45mSouthwest
Deal found 6/9$302
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/49:22 amGSP - SFO
1 stop8h 22mAmerican Airlines
Sun 9/712:14 pmSFO - GSP
1 stop7h 11mAmerican Airlines
Deal found 6/12$334
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/296:30 amGSP - SFO
1 stop6h 42mDelta
Thu 8/79:35 pmSFO - GSP
1 stop8h 26mDelta
Deal found 6/12$343
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2210:14 pmGSP - SFO
3 stops38h 14mMultiple Airlines
Sat 6/2811:59 pmSFO - GSP
2 stops18h 25mMultiple Airlines
Deal found 6/10$637

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Greenville

Fly to

San Francisco

Route

Depart

Return

Price

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 9/10

10:15 am-3:23 pm

1 stop8h 08m

San Francisco

Mon 9/15

9:15 pm-8:51 am

1 stop8h 36m

$297

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 9/10

9:30 am-6:25 pm

2 stops11h 55m

San Francisco

Mon 9/15

9:05 pm-9:50 am

1 stop9h 45m

$302

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Thu 9/4

9:22 am-2:44 pm

1 stop8h 22m

San Francisco

Sun 9/7

12:14 pm-10:25 pm

1 stop7h 11m

$334

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Tue 7/29

6:30 am-10:12 am

1 stop6h 42m

San Francisco

Thu 8/7

9:35 pm-9:01 am

1 stop8h 26m

$343

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sun 6/22

10:14 pm-9:28 am

3 stops38h 14m

San Francisco

Sat 6/28

11:59 pm-9:24 pm

2 stops18h 25m

$637

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Thu 7/3

4:33 pm-11:39 am

3 stops46h 06m

San Francisco

Sat 7/12

12:24 pm-8:48 am

3 stops41h 24m

$900

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 8/27

12:13 pm-7:07 pm

1 stop9h 54m

$149

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 8/27

10:25 am-5:55 pm

2 stops10h 30m

$154

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sun 7/27

10:06 pm-10:53 pm

3 stops27h 47m

$275

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 8/9

4:25 pm-7:41 am

2 stops18h 16m

$282

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 12 results
1
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Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Francisco

How far ahead should I book a flight from Greenville to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to San Francisco. Price data was last updated on June 9, 2025.

The price you pay for your flight from Greenville to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Greenville to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $276). Flying from Greenville to San Francisco in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to SFO?

Find hourly flight availability from Greenville to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

One of the essential ways to save on airfare from Greenville to San Francisco is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 6% on airfare.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 12, 2025.
To help decide which airline to fly from Greenville to San Francisco, see what other customers have to say about Breeze Airways, Southwest and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Overall

8.1

Entertainment

6.6

Comfort

8.2

Food

6.7

Boarding

8.3

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Greenville to San Francisco round-trip?

    Currently priced at $297, United Airlines will fly you from Greenville to San Francisco and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Southwest and American Airlines - these airlines can fly you to your destination from $302 and $334, respectively. United Airlines is priced at 36% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Greenville to San Francisco one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $149. Southwest flights start at $154 while deals on United Airlines start at $282 one-way.

  • Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.

  • Can I find deals for business class flights from Greenville to San Francisco?

    Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $276). Flying from Greenville to San Francisco in June is currently the most expensive (average of $364). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Roseville
Mountain View
South San Francisco
Livermore
Turlock
Santa Cruz
Manteca
Fairfield
Watsonville
Antioch
Hollister
Milpitas
Newark
Hayward
Alameda
Sunnyvale
Daly City
Union City
Campbell
Capitola

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Greenville to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Greenville to San Francisco

Discover the top 4 airlines that operate flights from Greenville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$312Average$487FlexibilityNo cancel feeOn-time69%
DeltaCheapest$318Average$464FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$346Average$481FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$366Average$488FlexibilityNo cancel feeOn-time63%

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