$169+ Cheap flights from Greenville to San Francisco (GSP - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SFO
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Francisco
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Best
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Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:58 pm -
1 stop8h 01m
Mon 12/75:00 am -
1 stop8h 50m
Deal found 9/20![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
2 stops8h 45m
Tue 10/279:35 pm -
1 stop9h 30m
Deal found 9/22![Southwest logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:25 pm -
1 stop10h 19m
Mon 10/261:27 pm -
1 stop6h 54m
Deal found 9/23![American Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:25 am -
2 stops10h 00m
Mon 10/269:35 pm -
1 stop9h 30m
Deal found 9/23![Southwest logo]()
$383
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:35 pm -
1 stop8h 24m
Fri 10/2311:30 pm -
1 stop7h 28m
Deal found 9/22![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:44 am -
1 stop11h 21m
Wed 1/65:00 am -
1 stop6h 58m
Deal found 9/20![American Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:25 pm -
1 stop10h 19m
Sat 10/318:41 am -
2 stops10h 24m
Deal found 9/19![American Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:46 pm -
1 stop9h 44m
Fri 10/2311:30 pm -
1 stop7h 28m
Deal found 9/21![United Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:25 am -
1 stop9h 10m
Sat 10/2411:40 pm -
2 stops9h 40m
Deal found 9/19![Southwest logo]()
$406
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:00 am -
1 stop8h 29m
Thu 12/3110:09 pm -
1 stop9h 25m
Deal found 9/22![American Airlines logo]()
$410
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:15 am -
1 stop10h 00m
Wed 12/166:00 am -
1 stop9h 30m
Deal found 9/22![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:20 am -
2 stops10h 25m
Sat 12/126:20 am -
2 stops8h 50m
Deal found 9/24![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:35 pm -
1 stop8h 24m
Fri 10/2311:30 pm -
1 stop7h 28m
Deal found 9/22![United Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:40 am -
2 stops12h 50m
Wed 12/168:00 am -
2 stops9h 45m
Deal found 9/22![Southwest logo]()
$417
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:40 am -
2 stops10h 41m
Mon 12/78:01 am -
1 stop7h 19m
Deal found 9/21![Delta logo]()
$437
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:05 am -
2 stops11h 05m
Wed 11/2511:35 pm -
2 stops9h 50m
Deal found 9/20![Southwest logo]()
$433
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:40 am -
2 stops10h 41m
Sun 12/1310:59 pm -
1 stop9h 14m
Deal found 9/24![Delta logo]()
$491
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:25 am -
2 stops9h 55m
Sun 10/189:35 pm -
1 stop13h 00m
Deal found 9/23![Southwest logo]()
$479
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:40 am -
2 stops12h 50m
Mon 11/3010:40 am -
2 stops9h 45m
Deal found 9/24![Southwest logo]()
$584
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated September 24, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:46 pm -
1 stop9h 44m
Fri 10/2311:30 pm -
1 stop7h 28m
Deal found 9/21![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:25 pm -
1 stop9h 26m
Fri 10/2311:30 pm -
1 stop7h 28m
Deal found 9/22![United Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:25 am -
2 stops9h 55m
Fri 10/239:35 pm -
1 stop10h 10m
Deal found 9/22![Southwest logo]()
$415
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:25 pm -
1 stop9h 26m
Tue 10/2711:20 pm -
1 stop7h 31m
Deal found 9/22![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
2 stops8h 45m
Tue 10/279:35 pm -
1 stop9h 30m
Deal found 9/22![Southwest logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:25 pm -
1 stop10h 19m
Sat 10/318:41 am -
2 stops10h 24m
Deal found 9/19![American Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:25 am -
1 stop9h 10m
Sat 10/2411:40 pm -
2 stops9h 40m
Deal found 9/19![Southwest logo]()
$406
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:25 pm -
1 stop10h 19m
Mon 10/261:27 pm -
1 stop6h 54m
Deal found 9/23![American Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:25 am -
2 stops10h 00m
Mon 10/269:35 pm -
1 stop9h 30m
Deal found 9/23![Southwest logo]()
$383
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:05 pm -
2 stops10h 00m
Mon 11/29:05 am -
2 stops10h 50m
Deal found 9/23![Southwest logo]()
$411
One-way flights from Greenville to San FranciscoSearch for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:10 pm -
1 stop7h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Southwest logo]()
$169
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:45 pm -
1 stop7h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![American Airlines logo]()
$185
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
2 stops8h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Southwest logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/811:28 am -
3 stops29h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$195
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:00 am -
2 stops8h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Southwest logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:28 am -
3 stops33h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:43 pm -
3 stops47h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:28 am -
3 stops23h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$233
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:42 pm -
1 stop8h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:24 pm -
3 stops29h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:24 pm -
3 stops48h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$243
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $369 (American Airlines) |
One-way from | $169 (Southwest) |
Popular in | January |
Cheapest in | November |
Average price | $479 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Wed 10/28
8:30 am-2:35 pm
1 stop9h 05m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$185
Quickest round-trip
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Sat 10/31
5:00 pm-9:45 pm
1 stop7h 45m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$185
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Sat 10/24
6:40 am-1:40 pm
2 stops10h 00m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$190
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Thu 11/5
6:40 am-3:10 pm
2 stops11h 30m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$190
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Tue 12/8
11:20 am-6:45 pm
2 stops10h 25m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$190
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Tue 10/27
11:28 am-6:19 pm
3 stops33h 51m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$205
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Tue 11/24
6:45 am-3:15 pm
2 stops11h 30m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$244
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Tue 12/22
6:00 am-4:00 pm
2 stops13h 00m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$333
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Thu 11/26
9:15 am-4:15 pm
1 stop10h 00m
San Francisco
Wed 12/16
6:00 am-6:30 pm
1 stop9h 30m
$369
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Wed 12/9
11:20 am-6:45 pm
2 stops10h 25m
San Francisco
Sat 12/12
6:20 am-6:10 pm
2 stops8h 50m
$379
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Francisco in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Greenville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
GSP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Francisco
How far ahead should I book a flight from Greenville to San Francisco?
The price you pay for your flight from Greenville to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Francisco?
Currently, November is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $474). Flying from Greenville to San Francisco in January is currently the most expensive (average of $668). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Francisco?
Airfare is below average for this route at the moment.
Greenville to San Francisco flights typically cost between $466 and $621 in December.The cheapest round-trip price found within the last 5 days was $369 on American Airlines (Dec 3-Dec 7).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 24, 2026.
Read through reviews of airlines operating flights from Greenville to San Francisco, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Greenville and San Francisco flights
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Top 4 airlines flying from Greenville to San Francisco
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$318 | Average$568 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$334 | Average$546 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$346 | Average$540 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$402 | Average$503 | FlexibilityNo cancel fee | On-time63% |