$153+ Cheap flights from Greenville to San Francisco (GSP - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SFO
Nov 7 — Nov 141
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Francisco
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Best
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Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:44 pm -
1 stop10h 04m
Mon 12/78:01 am -
1 stop8h 56m
Deal found 10/7![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:05 am -
1 stop8h 45m
Tue 11/1011:35 pm -
2 stops11h 35m
Deal found 10/5![Southwest logo]()
$310
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2511:20 am -
1 stop7h 30m
Tue 1/59:25 pm -
1 stop10h 00m
Deal found 10/6![Southwest logo]()
$335
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:56 am -
1 stop10h 15m
Sat 11/145:53 pm -
2 stops13h 18m
Deal found 10/7![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:00 pm -
1 stop7h 39m
Tue 11/311:30 pm -
1 stop7h 31m
Deal found 10/7![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:30 am -
1 stop9h 05m
Sat 10/316:00 am -
1 stop7h 25m
Deal found 10/5![Southwest logo]()
$350
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:05 am -
2 stops9h 55m
Wed 11/116:10 am -
2 stops9h 00m
Deal found 10/7![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:37 pm -
1 stop10h 16m
Fri 10/305:00 am -
1 stop7h 03m
Deal found 10/5![United Airlines logo]()
$377
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:44 pm -
1 stop10h 04m
Mon 12/78:01 am -
1 stop8h 56m
Deal found 10/7![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:05 am -
2 stops9h 55m
Thu 12/108:20 am -
2 stops9h 25m
Deal found 10/7![Southwest logo]()
$315
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:48 pm -
1 stop8h 42m
Thu 12/2411:30 pm -
1 stop7h 03m
Deal found 10/4![United Airlines logo]()
$460
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:05 am -
2 stops9h 55m
Sun 11/2210:40 am -
2 stops9h 20m
Deal found 10/7![Southwest logo]()
$431
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:40 am -
1 stop10h 07m
Sun 12/1311:59 pm -
1 stop6h 41m
Deal found 10/5![Delta logo]()
$477
This Southwest deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:55 pm -
2 stops10h 30m
Mon 11/3010:45 pm -
1 stop12h 25m
Deal found 10/3![Southwest logo]()
$462
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:40 am -
2 stops12h 00m
Thu 12/248:20 am -
2 stops9h 25m
Deal found 10/4![Southwest logo]()
$478
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:05 am -
1 stop8h 45m
Tue 12/229:25 pm -
1 stop9h 35m
Deal found 10/7![Southwest logo]()
$488
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated October 8, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated October 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:45 pm -
1 stop7h 59m
Wed 10/286:47 am -
1 stop6h 48m
Deal found 10/6![American Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:00 pm -
1 stop7h 39m
Tue 11/311:30 pm -
1 stop7h 31m
Deal found 10/7![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:30 am -
1 stop9h 05m
Sat 10/316:00 am -
1 stop7h 25m
Deal found 10/5![Southwest logo]()
$350
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:37 pm -
1 stop10h 16m
Fri 10/305:00 am -
1 stop7h 03m
Deal found 10/5![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:30 am -
1 stop9h 05m
Fri 10/309:35 am -
2 stops10h 15m
Deal found 10/5![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:05 am -
1 stop8h 45m
Tue 11/1011:35 pm -
2 stops11h 35m
Deal found 10/5![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:20 am -
1 stop10h 00m
Wed 11/1110:59 pm -
1 stop9h 08m
Deal found 10/7![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:05 am -
2 stops9h 55m
Wed 11/116:10 am -
2 stops9h 00m
Deal found 10/7![Southwest logo]()
$372
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:56 am -
1 stop10h 15m
Sat 11/145:53 pm -
2 stops13h 18m
Deal found 10/7![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:17 pm -
1 stop8h 14m
Sun 11/226:00 am -
1 stop7h 12m
Deal found 10/7![American Airlines logo]()
$388
One-way flights from Greenville to San FranciscoSearch for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
Search for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:20 am -
1 stop10h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Delta logo]()
$153
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:05 am -
2 stops9h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Southwest logo]()
$158
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:45 am -
2 stops11h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Southwest logo]()
$188
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:22 pm -
1 stop9h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![American Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/308:32 pm -
3 stops42h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:24 pm -
3 stops40h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$204
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:40 am -
2 stops10h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Delta logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/218:32 pm -
2 stops50h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Multiple Airlines logo]()
$217
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:37 pm -
1 stop8h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![United Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:24 pm -
2 stops18h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$221
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2210:35 am -
1 stop12h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Southwest logo]()
$235
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $305 (Delta) |
One-way from | $153 (Delta) |
Popular in | January |
Cheapest in | November |
Average price | $568 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Wed 11/4
6:49 am-12:19 pm
1 stop8h 30m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$153
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Tue 10/27
7:20 am-2:20 pm
1 stop10h 00m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$153
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Wed 12/2
7:05 am-2:00 pm
2 stops9h 55m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$158
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Sun 12/20
6:45 am-3:15 pm
2 stops11h 30m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$188
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Thu 12/24
7:05 am-2:00 pm
2 stops9h 55m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$188
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Thu 12/24
7:37 pm-1:30 am
1 stop8h 53m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$218
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Tue 12/22
10:35 am-8:10 pm
1 stop12h 35m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$235
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Mon 12/21
8:32 pm-12:41 am
3 stops31h 09m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$241
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Sun 11/1
6:40 am-2:25 pm
2 stops10h 45m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$280
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Mon 12/21
4:10 pm-11:09 pm
1 stop9h 59m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$285
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Francisco in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Greenville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
GSP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Francisco
How far ahead should I book a flight from Greenville to San Francisco?
The price you pay for your flight from Greenville to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 36 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Francisco?
Currently, November is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $474). Flying from Greenville to San Francisco in January is currently the most expensive (average of $668). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Francisco?
Airfare is below average for this route at the moment.
Greenville to San Francisco flights typically cost between $423 and $626 in December.The cheapest round-trip price found within the last 5 days was $305 on Delta (Dec 3-Dec 7).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated October 8, 2026.
Read through reviews of airlines operating flights from Greenville to San Francisco, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
San Bruno
Emeryville
Hayward
Burlingame
Rancho Cordova
Roseville
Redwood City
Cupertino
Newark
Fairfield
San Ramon
Manteca
Vallejo
San Carlos
Turlock
Davis
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Find flights from Greenville to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and San Francisco flights
Browse other Greenville and San Francisco flight options. Last updated on October 8, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on October 8, 2026.
Popular flight searches
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Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 8, 2026.
Top 4 airlines flying from Greenville to San Francisco
Discover the top 4 airlines that operate flights from Greenville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$318 | Average$568 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$334 | Average$546 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$336 | Average$542 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$402 | Average$503 | FlexibilityNo cancel fee | On-time63% |