$160+ Cheap flights from Greenville to San Francisco (GSP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SFO
May 12 — May 191
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Francisco
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Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:52 pm
GSP
- SFO
1 stop8h 57m
United Airlines
Tue 5/195:30 am
SFO
- GSP
1 stop8h 29m
United Airlines
Deal found 4/11![United Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Tue 6/169:10 pm
SFO
- GSP
1 stop13h 00m
Southwest
Deal found 4/8![Southwest logo]()
$388
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:30 am
GSP
- SFO
1 stop8h 33m
United Airlines
Mon 5/411:10 pm
SFO
- GSP
1 stop7h 37m
United Airlines
Deal found 4/8![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:55 pm
GSP
- SFO
2 stops11h 15m
Southwest
Tue 5/197:40 am
SFO
- GSP
2 stops11h 00m
Southwest
Deal found 4/11![Southwest logo]()
$393
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Mon 5/48:50 am
SFO
- GSP
2 stops10h 25m
Southwest
Deal found 4/8![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:36 am
GSP
- SFO
1 stop8h 49m
United Airlines
Mon 5/1110:35 pm
SFO
- GSP
1 stop8h 23m
United Airlines
Deal found 4/8![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:20 am
GSP
- SFO
1 stop9h 56m
American Airlines
Mon 5/1811:59 pm
SFO
- GSP
1 stop8h 45m
American Airlines
Deal found 4/7![American Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
GSP
- SFO
1 stop8h 35m
Southwest
Sat 5/98:20 am
SFO
- GSP
2 stops9h 20m
Southwest
Deal found 4/11![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:25 am
GSP
- SFO
2 stops9h 10m
Southwest
Mon 5/1111:25 pm
SFO
- GSP
2 stops10h 45m
Southwest
Deal found 4/8![Southwest logo]()
$409
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 12, 2026.
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Sat 5/95:40 am
SFO
- GSP
2 stops12h 00m
Southwest
Deal found 4/11![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:40 pm
GSP
- SFO
1 stop8h 35m
United Airlines
Sun 7/510:35 pm
SFO
- GSP
1 stop8h 20m
United Airlines
Deal found 4/11![United Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:43 am
GSP
- SFO
1 stop9h 06m
Delta
Mon 5/1811:59 pm
SFO
- GSP
1 stop9h 06m
Delta
Deal found 4/10![Delta logo]()
$429
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:40 pm
GSP
- SFO
1 stop8h 35m
United Airlines
Tue 7/710:35 pm
SFO
- GSP
1 stop8h 20m
United Airlines
Deal found 4/11![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:00 am
GSP
- SFO
1 stop9h 25m
Southwest
Sun 5/3110:55 pm
SFO
- GSP
1 stop10h 05m
Southwest
Deal found 4/11![Southwest logo]()
$438
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:50 pm
GSP
- SFO
2 stops12h 25m
Southwest
Sat 6/2011:40 pm
SFO
- GSP
2 stops10h 25m
Southwest
Deal found 4/8![Southwest logo]()
$441
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:40 pm
GSP
- SFO
1 stop8h 35m
United Airlines
Wed 7/156:05 am
SFO
- GSP
1 stop7h 55m
United Airlines
Deal found 4/9![United Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:00 am
GSP
- SFO
2 stops11h 00m
Southwest
Sun 7/511:40 pm
SFO
- GSP
2 stops9h 35m
Southwest
Deal found 4/11![Southwest logo]()
$473
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/131:55 pm
GSP
- SFO
2 stops12h 35m
Southwest
Sun 6/2111:40 pm
SFO
- GSP
2 stops9h 35m
Southwest
Deal found 4/11![Southwest logo]()
$477
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated April 12, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated April 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:30 am
GSP
- SFO
1 stop8h 33m
United Airlines
Mon 5/411:10 pm
SFO
- GSP
1 stop7h 37m
United Airlines
Deal found 4/8![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:55 pm
GSP
- SFO
1 stop10h 30m
Southwest
Mon 5/48:50 am
SFO
- GSP
2 stops10h 25m
Southwest
Deal found 4/8![Southwest logo]()
$396
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
GSP
- SFO
1 stop8h 35m
Southwest
Sat 5/98:20 am
SFO
- GSP
2 stops9h 20m
Southwest
Deal found 4/11![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:36 am
GSP
- SFO
1 stop8h 49m
United Airlines
Mon 5/1110:35 pm
SFO
- GSP
1 stop8h 23m
United Airlines
Deal found 4/8![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:25 am
GSP
- SFO
2 stops9h 10m
Southwest
Mon 5/1111:25 pm
SFO
- GSP
2 stops10h 45m
Southwest
Deal found 4/8![Southwest logo]()
$409
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:25 am
GSP
- SFO
2 stops9h 10m
Southwest
Wed 5/139:15 pm
SFO
- GSP
1 stop13h 00m
Southwest
Deal found 4/7![Southwest logo]()
$410
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:52 pm
GSP
- SFO
1 stop8h 57m
United Airlines
Tue 5/195:30 am
SFO
- GSP
1 stop8h 29m
United Airlines
Deal found 4/11![United Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:55 pm
GSP
- SFO
2 stops11h 15m
Southwest
Tue 5/197:40 am
SFO
- GSP
2 stops11h 00m
Southwest
Deal found 4/11![Southwest logo]()
$393
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:20 am
GSP
- SFO
1 stop9h 56m
American Airlines
Mon 5/1811:59 pm
SFO
- GSP
1 stop8h 45m
American Airlines
Deal found 4/7![American Airlines logo]()
$400
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:33 am
GSP
- SFO
2 stops40h 31m
Multiple Airlines
Sun 5/248:48 pm
SFO
- GSP
1 stop20h 52m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$425
One-way flights from Greenville to San FranciscoSearch for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
Search for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:43 pm
GSP
- SFO
2 stops32h 21m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:28 pm
GSP
- SFO
3 stops23h 02m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:28 pm
GSP
- SFO
2 stops35h 55m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:18 pm
GSP
- SFO
2 stops24h 16m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:28 pm
GSP
- SFO
2 stops48h 54m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$181
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:45 pm
GSP
- SFO
1 stop10h 05m
United Airlines
Deal found 4/11![United Airlines logo]()
$192
This Southwest deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:50 pm
GSP
- SFO
2 stops12h 15m
Southwest
Deal found 4/11![Southwest logo]()
$197
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:06 pm
GSP
- SFO
1 stop8h 13m
American Airlines
Deal found 4/7![American Airlines logo]()
$200
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $383 (United Airlines) |
One-way from | $160 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $532 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Wed 5/6
1:55 pm-9:25 pm
1 stop10h 30m
San Francisco
Sat 5/9
5:40 am-8:40 pm
2 stops12h 00m
$396
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Tue 6/30
7:40 pm-1:15 am
1 stop8h 35m
San Francisco
Sun 7/5
10:35 pm-9:55 am
1 stop8h 20m
$425
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Tue 6/30
7:40 pm-1:15 am
1 stop8h 35m
San Francisco
Tue 7/7
10:35 pm-9:55 am
1 stop8h 20m
$425
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Wed 5/13
11:43 am-5:49 pm
1 stop9h 06m
San Francisco
Mon 5/18
11:59 pm-12:05 pm
1 stop9h 06m
$429
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Sat 5/30
8:00 am-2:25 pm
1 stop9h 25m
San Francisco
Sun 5/31
10:55 pm-12:00 pm
1 stop10h 05m
$438
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Tue 6/16
12:50 pm-10:15 pm
2 stops12h 25m
San Francisco
Sat 6/20
11:40 pm-1:05 pm
2 stops10h 25m
$441
Quickest round-trip
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Fri 7/10
7:40 pm-1:15 am
1 stop8h 35m
San Francisco
Wed 7/15
6:05 am-5:00 pm
1 stop7h 55m
$467
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Tue 6/30
7:00 am-3:00 pm
2 stops11h 00m
San Francisco
Sun 7/5
11:40 pm-12:15 pm
2 stops9h 35m
$473
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Sat 6/13
1:55 pm-11:30 pm
2 stops12h 35m
San Francisco
Sun 6/21
11:40 pm-12:15 pm
2 stops9h 35m
$477
Cheapest one-way
Quickest one-way
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Sat 6/6
7:20 am-2:15 pm
1 stop9h 55m
$200
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Francisco in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Greenville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
GSP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Francisco
How far ahead should I book a flight from Greenville to San Francisco?
Use this chart to determine the optimal time to book a round-trip flight from Greenville to San Francisco. Price data was last updated on April 9, 2026.
The price you pay for your flight from Greenville to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 72 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Francisco?
Currently, August is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $106). Flying from Greenville to San Francisco in December is currently the most expensive (average of $338). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 12, 2026.
Read through reviews of airlines operating flights from Greenville to San Francisco, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Greenville and San Francisco flights
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Top 4 airlines flying from Greenville to San Francisco
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$472 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$311 | Average$488 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$330 | Average$457 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$331 | Average$477 | FlexibilityNo cancel fee | On-time71% |