$192+ Cheap flights from Greenville to San Francisco (GSP - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SFO
Jun 5 — Jun 121
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to San Francisco with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Greenville to San FranciscoExplore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:28 pm
GSP
- SFO
2 stops48h 29m
Multiple Airlines
Thu 5/288:48 pm
SFO
- GSP
1 stop20h 52m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:37 pm
GSP
- SFO
1 stop10h 33m
American Airlines
Tue 6/211:25 am
SFO
- GSP
1 stop8h 32m
American Airlines
Deal found 5/1![American Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:25 pm
GSP
- SFO
1 stop8h 05m
American Airlines
Tue 6/99:52 pm
SFO
- GSP
1 stop7h 26m
American Airlines
Deal found 5/5![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:54 pm
GSP
- SFO
1 stop7h 54m
American Airlines
Mon 6/15:00 am
SFO
- GSP
1 stop7h 41m
American Airlines
Deal found 5/5![American Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:25 pm
GSP
- SFO
2 stops8h 55m
Southwest
Tue 6/27:40 am
SFO
- GSP
2 stops11h 00m
Southwest
Deal found 5/1![Southwest logo]()
$401
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:25 pm
GSP
- SFO
1 stop8h 56m
American Airlines
Fri 6/512:26 am
SFO
- GSP
1 stop9h 41m
American Airlines
Deal found 5/2![American Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:05 am
GSP
- SFO
1 stop7h 45m
Southwest
Thu 9/105:10 am
SFO
- GSP
2 stops10h 10m
Southwest
Deal found 5/5![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:50 pm
GSP
- SFO
2 stops12h 15m
Southwest
Tue 6/96:00 am
SFO
- GSP
2 stops10h 00m
Southwest
Deal found 5/5![Southwest logo]()
$405
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:50 pm
GSP
- SFO
1 stop11h 05m
Southwest
Wed 6/106:00 am
SFO
- GSP
2 stops10h 00m
Southwest
Deal found 5/6![Southwest logo]()
$406
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 pm
GSP
- SFO
2 stops8h 40m
Southwest
Mon 6/811:40 pm
SFO
- GSP
2 stops10h 30m
Southwest
Deal found 5/5![Southwest logo]()
$409
Best flights from Greenville to San FranciscoDiscover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
Discover carefully curated flight deals from Greenville to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:00 am
GSP
- SFO
1 stop8h 25m
Southwest
Tue 9/2910:30 pm
SFO
- GSP
1 stop8h 45m
Southwest
Deal found 5/5![Southwest logo]()
$395
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:42 pm
GSP
- SFO
1 stop8h 04m
Delta
Mon 6/811:59 pm
SFO
- GSP
1 stop9h 19m
Delta
Deal found 5/5![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:47 pm
GSP
- SFO
1 stop8h 29m
United Airlines
Sun 10/410:55 pm
SFO
- GSP
1 stop7h 53m
United Airlines
Deal found 5/5![United Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:05 am
GSP
- SFO
2 stops9h 15m
Southwest
Tue 6/306:00 am
SFO
- GSP
2 stops10h 00m
Southwest
Deal found 5/1![Southwest logo]()
$435
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:20 pm
GSP
- SFO
1 stop9h 34m
Delta
Sun 8/1610:10 pm
SFO
- GSP
1 stop9h 30m
Delta
Deal found 5/3![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:05 am
GSP
- SFO
2 stops9h 15m
Southwest
Tue 6/306:00 am
SFO
- GSP
2 stops10h 00m
Southwest
Deal found 5/1![Southwest logo]()
$435
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:00 am
GSP
- SFO
2 stops9h 10m
Southwest
Fri 8/285:10 am
SFO
- GSP
2 stops10h 10m
Southwest
Deal found 5/5![Southwest logo]()
$443
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/141:50 pm
GSP
- SFO
1 stop9h 00m
Southwest
Tue 7/285:50 am
SFO
- GSP
2 stops10h 10m
Southwest
Deal found 5/2![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:20 am
GSP
- SFO
2 stops10h 45m
Southwest
Sun 10/46:00 am
SFO
- GSP
2 stops10h 15m
Southwest
Deal found 5/5![Southwest logo]()
$477
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1212:55 pm
GSP
- SFO
1 stop10h 00m
Southwest
Fri 6/198:45 am
SFO
- GSP
2 stops11h 05m
Southwest
Deal found 5/1![Southwest logo]()
$478
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:00 am
GSP
- SFO
2 stops10h 40m
Southwest
Sun 8/1611:05 pm
SFO
- GSP
1 stop10h 25m
Southwest
Deal found 5/3![Southwest logo]()
$478
Last-minute flights from Greenville to San FranciscoDiscover last-minute flight deals from Greenville to San Francisco. Data last updated May 6, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Francisco. Data last updated May 6, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:28 pm
GSP
- SFO
2 stops48h 29m
Multiple Airlines
Thu 5/288:48 pm
SFO
- GSP
1 stop20h 52m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:54 pm
GSP
- SFO
1 stop7h 54m
American Airlines
Mon 6/15:00 am
SFO
- GSP
1 stop7h 41m
American Airlines
Deal found 5/5![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:37 pm
GSP
- SFO
1 stop10h 33m
American Airlines
Tue 6/211:25 am
SFO
- GSP
1 stop8h 32m
American Airlines
Deal found 5/1![American Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:25 pm
GSP
- SFO
2 stops8h 55m
Southwest
Tue 6/27:40 am
SFO
- GSP
2 stops11h 00m
Southwest
Deal found 5/1![Southwest logo]()
$401
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:25 pm
GSP
- SFO
1 stop8h 05m
American Airlines
Tue 6/99:52 pm
SFO
- GSP
1 stop7h 26m
American Airlines
Deal found 5/5![American Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:50 pm
GSP
- SFO
2 stops12h 15m
Southwest
Tue 6/96:00 am
SFO
- GSP
2 stops10h 00m
Southwest
Deal found 5/5![Southwest logo]()
$405
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:50 pm
GSP
- SFO
1 stop11h 05m
Southwest
Wed 6/106:00 am
SFO
- GSP
2 stops10h 00m
Southwest
Deal found 5/6![Southwest logo]()
$406
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:25 pm
GSP
- SFO
1 stop8h 56m
American Airlines
Fri 6/512:26 am
SFO
- GSP
1 stop9h 41m
American Airlines
Deal found 5/2![American Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 pm
GSP
- SFO
2 stops8h 40m
Southwest
Mon 6/811:40 pm
SFO
- GSP
2 stops10h 30m
Southwest
Deal found 5/5![Southwest logo]()
$409
One-way flights from Greenville to San FranciscoSearch for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
Search for one-way flight options from Greenville to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:09 pm
GSP
- SFO
1 stop8h 56m
Delta
Deal found 5/4![Delta logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:59 pm
GSP
- SFO
2 stops46h 17m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$196
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:50 pm
GSP
- SFO
2 stops12h 15m
Southwest
Deal found 5/4![Southwest logo]()
$197
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:50 pm
GSP
- SFO
1 stop9h 00m
Southwest
Deal found 5/4![Southwest logo]()
$198
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:45 am
GSP
- SFO
1 stop9h 11m
Delta
Deal found 5/4![Delta logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:54 pm
GSP
- SFO
3 stops54h 33m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:40 pm
GSP
- SFO
3 stops27h 50m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$233
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:25 pm
GSP
- SFO
1 stop10h 23m
American Airlines
Deal found 5/5![American Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2212:50 pm
GSP
- SFO
2 stops12h 25m
Southwest
Deal found 5/4![Southwest logo]()
$245
Find flight deals from Greenville to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $370 (Kiwi.com) |
One-way from | $192 (Delta) |
Popular in | January |
Cheapest in | August |
Average price | $577 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Wed 9/16
11:00 am-4:25 pm
1 stop8h 25m
San Francisco
Tue 9/29
10:30 pm-10:15 am
1 stop8h 45m
$395
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Thu 6/4
7:42 pm-12:46 am
1 stop8h 04m
San Francisco
Mon 6/8
11:59 pm-12:18 pm
1 stop9h 19m
$399
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Fri 6/26
7:05 am-1:20 pm
2 stops9h 15m
San Francisco
Tue 6/30
6:00 am-7:00 pm
2 stops10h 00m
$435
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Thu 6/25
7:05 am-1:20 pm
2 stops9h 15m
San Francisco
Tue 6/30
6:00 am-7:00 pm
2 stops10h 00m
$435
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Mon 8/24
7:00 am-1:10 pm
2 stops9h 10m
San Francisco
Fri 8/28
5:10 am-6:20 pm
2 stops10h 10m
$443
Quickest round-trip
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Sun 9/27
7:47 pm-1:16 am
1 stop8h 29m
San Francisco
Sun 10/4
10:55 pm-9:48 am
1 stop7h 53m
$467
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Thu 8/13
5:20 pm-11:54 pm
1 stop9h 34m
San Francisco
Sun 8/16
10:10 pm-10:40 am
1 stop9h 30m
$467
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Tue 7/14
1:50 pm-7:50 pm
1 stop9h 00m
San Francisco
Tue 7/28
5:50 am-7:00 pm
2 stops10h 10m
$472
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Sun 9/27
7:20 am-3:05 pm
2 stops10h 45m
San Francisco
Sun 10/4
6:00 am-7:15 pm
2 stops10h 15m
$477
GreenvilleSan Francisco
GSP - SFO
GSPSFO
Greenville
Fri 6/12
12:55 pm-7:55 pm
1 stop10h 00m
San Francisco
Fri 6/19
8:45 am-10:50 pm
2 stops11h 05m
$478
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Francisco in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Greenville-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
GSP-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Francisco
How far ahead should I book a flight from Greenville to San Francisco?
The price you pay for your flight from Greenville to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 71 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Francisco?
Currently, August is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $412). Flying from Greenville to San Francisco in January is currently the most expensive (average of $668). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 6, 2026.
Read through reviews of airlines operating flights from Greenville to San Francisco, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.9
Food
7.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
7.9
Food
7.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
7.9
Food
7.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
7.9
Food
7.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
7.9
Food
7.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Emeryville
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
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Greenville and San Francisco flights
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Top 4 airlines flying from Greenville to San Francisco
Discover the top 4 airlines that operate flights from Greenville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$276 | Average$515 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$311 | Average$508 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$330 | Average$495 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$332 | Average$523 | FlexibilityNo cancel fee | On-time71% |