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$102+ Cheap flights from South Carolina to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SAN
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from South Carolina to San Diego

Keep the following information in mind while searching for South Carolina to San Diego flight deals. Data was last updated September 17, 2025.

Round-trip from

$275
(JetBlue)

One-way from

$102
(Trip.com)

Popular in

June

Cheapest in

September

Average price

$365
From South Carolina to San Diego
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One-way flight from South Carolina to San Diego
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Highest demand for flights based on searches. 6% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from South Carolina to San Diego

Cheapest flights from South Carolina to San Diego
Explore the most affordable flight options available from South Carolina to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This JetBlue deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1711:10 amCHS - SAN
1 stop11h 20mJetBlue
Mon 10/208:55 pmSAN - CHS
1 stop12h 10mJetBlue
Deal found 9/17$275
This JetBlue deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2411:10 amCHS - SAN
1 stop11h 20mJetBlue
Sat 11/19:20 pmSAN - CHS
1 stop11h 08mJetBlue
Deal found 9/17$277
This JetBlue deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2212:25 pmSAV - SAN
1 stop10h 04mJetBlue
Mon 10/279:05 pmSAN - SAV
1 stop10h 29mJetBlue
Deal found 9/17$297
This Trip.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2211:16 amSAV - SAN
1 stop10h 49mJetBlue
Sun 10/269:05 pmSAN - SAV
1 stop10h 29mJetBlue
Deal found 9/15$305
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:55 pmSAV - SAN
1 stop7h 19mDelta
Mon 10/278:00 amSAN - SAV
1 stop6h 39mDelta
Deal found 9/17$307
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/253:42 pmCAE - SAN
1 stop9h 32mUnited Airlines
Tue 10/2810:00 pmSAN - CAE
1 stop8h 59mUnited Airlines
Deal found 9/16$309
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/294:40 pmSAV - SAN
1 stop8h 40mUnited Airlines
Sat 11/19:00 amSAN - SAV
2 stops9h 33mUnited Airlines
Deal found 9/17$312
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:37 pmSAV - SAN
1 stop8h 37mDelta
Tue 11/412:00 pmSAN - SAV
1 stop8h 43mDelta
Deal found 9/17$316
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:00 amCHS - SAN
1 stop8h 56mDelta
Wed 10/297:10 amSAN - CHS
1 stop10h 50mDelta
Deal found 9/17$317
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:59 pmAGS - SAN
1 stop6h 21mDelta
Fri 10/249:48 pmSAN - AGS
1 stop8h 17mDelta
Deal found 9/17$317
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/234:30 pmSAV - SAN
1 stop8h 45mUnited Airlines
Mon 10/2710:18 pmSAN - SAV
1 stop9h 05mUnited Airlines
Deal found 9/15$317
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/228:45 amSAV - SAN
2 stops12h 55mSouthwest
Mon 10/279:10 pmSAN - SAV
1 stop9h 50mSouthwest
Deal found 9/15$318

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from South Carolina to San Diego that are best for you.

Fly from

South Carolina

Fly to

San Diego

Route

Depart

Return

Price

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

Fri 10/24

11:10 am-7:30 pm

1 stop11h 20m

San Diego

Sat 11/1

9:20 pm-11:28 am

1 stop11h 08m

$277

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Wed 11/5

11:19 am-7:51 pm

1 stop11h 32m

San Diego

Mon 11/10

9:05 pm-10:34 am

1 stop10h 29m

$297

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Sat 1/10

12:16 pm-8:08 pm

1 stop10h 52m

San Diego

Sun 1/18

9:22 pm-11:31 am

1 stop11h 09m

$297

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Thu 3/5

11:19 am-7:34 pm

1 stop11h 15m

San Diego

Mon 3/9

9:22 pm-11:31 am

1 stop11h 09m

$297

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Wed 10/29

12:25 pm-7:16 pm

1 stop9h 51m

San Diego

Sat 11/1

9:05 pm-11:34 am

1 stop11h 29m

$297

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Wed 10/22

11:16 am-7:05 pm

1 stop10h 49m

San Diego

Sun 10/26

9:05 pm-10:34 am

1 stop10h 29m

$305

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Wed 10/29

11:19 am-7:31 pm

1 stop11h 12m

San Diego

Sun 11/2

9:05 pm-10:34 am

1 stop10h 29m

$305

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Wed 11/5

7:00 pm-11:25 pm

1 stop7h 25m

San Diego

Mon 11/10

6:40 am-6:35 pm

1 stop8h 55m

$307

ColumbiaSan Diego

CAE - SAN

CAESAN

Columbia Metropolitan

Sat 10/25

5:08 am-9:09 am

1 stop7h 01m

San Diego

Sat 11/8

9:54 pm-10:39 am

1 stop9h 45m

$309

ColumbiaSan Diego

CAE - SAN

CAESAN

Columbia Metropolitan

Sat 10/25

3:42 pm-10:14 pm

1 stop9h 32m

San Diego

Tue 10/28

7:50 pm-9:59 am

2 stops11h 09m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to San Diego

What is the cheapest month to book a flight from South Carolina to San Diego?

Currently, August is the cheapest month in which you can book a flight from South Carolina to San Diego (average of $286). Flying from South Carolina to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SAN?

Find hourly flight availability from South Carolina to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from South Carolina to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from South Carolina?

    San Diego (SAN) is the airport you will fly into if you book a flight from South Carolina to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How long is the flight from South Carolina to San Diego?

    A quick flight from South Carolina to San Diego can take about 7h 01m. JetBlue provides one of the quickest options available for as low as $309. South Carolina and San Diego are separated by a distance of 2072 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South Carolina to San Diego one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $134. JetBlue flights start at $138 while deals on Southwest start at $140 one-way.

  • What are the most popular routes from South Carolina to San Diego?

    The most popular flight routes from South Carolina to San Diego are Charlotte Douglas - San Diego, Charleston - San Diego and Savannah/Hilton Head - San Diego.

  • Can I find deals for flights from South Carolina to San Diego that include hotel bookings?

    Yes. In addition to deals on South Carolina to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to San Diego.

  • Can I find deals for business class flights from South Carolina to San Diego?

    Yes. Cheapflights offers flight deals from South Carolina to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to San Diego?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to San Diego (average of $286). Flying from South Carolina to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to San Diego

Discover the top 6 airlines that operate flights from South Carolina to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$70Average$353FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$170Average$265FlexibilityNo cancel feeOn-time62%
DeltaCheapest$257Average$441FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$268Average$424FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$294Average$483FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$336Average$471FlexibilityNo cancel feeOn-time63%

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