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$90+ Cheap flights from South Carolina to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SAN
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from South Carolina to San Diego

Keep the following information in mind while searching for South Carolina to San Diego flight deals. Data was last updated July 31, 2025.

Round-trip from

$234
(Booking.com)

One-way from

$92
(Booking.com)

Popular in

June

Cheapest in

May

Average price

$476
From South Carolina to San Diego
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One-way flight from South Carolina to San Diego
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Highest demand for flights based on searches. 6% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from South Carolina to San Diego

Cheapest flights from South Carolina to San Diego
Explore the most affordable flight options available from South Carolina to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Booking.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2810:38 amCHS - SAN
2 stops15h 59mSpirit Airlines
Thu 9/47:47 pmSAN - CHS
2 stops9h 28mSpirit Airlines
Deal found 7/29$234
This Flysmarter deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/411:10 amCHS - SAN
1 stop11h 20mJetBlue
Fri 9/129:35 pmSAN - CHS
1 stop11h 32mJetBlue
Deal found 7/29$243
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/144:20 pmCAE - SAN
2 stops18h 01mSpirit Airlines
Sun 8/171:17 pmSAN - CAE
2 stops18h 27mSpirit Airlines
Deal found 7/30$250
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3012:55 pmAGS - SAN
1 stop8h 56mAmerican Airlines
Sat 9/66:15 amSAN - AGS
1 stop6h 35mAmerican Airlines
Deal found 7/29$256
This CheapOair deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/162:24 pmCLT - SAN
2 stops20h 00mSpirit Airlines
Sun 10/197:47 pmSAN - CLT
2 stops14h 42mSpirit Airlines
Deal found 7/29$264
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/710:19 pmCLT - SAN
1 stop20h 40mFrontier
Tue 8/126:25 amSAN - CLT
1 stop7h 11mFrontier
Deal found 7/29$265
This CheapOair deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/22:39 pmCLT - SAN
2 stops11h 55mMultiple Airlines
Sun 10/56:35 amSAN - CLT
1 stop6h 50mMultiple Airlines
Deal found 7/31$274
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/274:49 pmSAV - SAN
2 stops28h 07mSpirit Airlines
Wed 9/31:17 pmSAN - SAV
2 stops18h 48mSpirit Airlines
Deal found 7/30$286
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/65:44 pmAGS - SAN
1 stop6h 31mDelta
Tue 9/96:25 amSAN - AGS
1 stop7h 39mDelta
Deal found 7/28$297
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/166:45 amMYR - SAN
3 stops19h 52mSpirit Airlines
Wed 8/201:17 pmSAN - MYR
2 stops20h 56mSpirit Airlines
Deal found 7/29$297
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/217:36 pmCAE - SAN
1 stop7h 35mAmerican Airlines
Fri 8/2910:50 amSAN - CAE
1 stop8h 33mAmerican Airlines
Deal found 7/31$308
This Expedia deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/279:56 amSAV - SAN
1 stop12h 01mJetBlue
Wed 9/38:55 pmSAN - SAV
1 stop10h 36mJetBlue
Deal found 7/30$312

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from South Carolina to San Diego that are best for you.

Fly from

South Carolina

Fly to

San Diego

Route

Depart

Return

Price

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

Thu 8/28

10:38 am-11:37 pm

2 stops15h 59m

San Diego

Thu 9/4

7:47 pm-8:15 am

2 stops9h 28m

$234

CharlestonSan Diego

CHS - SAN

CHSSAN

Charleston

Thu 9/4

11:10 am-7:30 pm

1 stop11h 20m

San Diego

Fri 9/12

9:35 pm-12:07 pm

1 stop11h 32m

$243

ColumbiaSan Diego

CAE - SAN

CAESAN

Columbia Metropolitan

Thu 8/14

4:20 pm-7:21 am

2 stops18h 01m

San Diego

Sun 8/17

1:17 pm-10:44 am

2 stops18h 27m

$250

AugustaSan Diego

AGS - SAN

AGSSAN

Augusta Bush Field

Sat 8/30

12:55 pm-6:51 pm

1 stop8h 56m

San Diego

Sat 9/6

6:15 am-3:50 pm

1 stop6h 35m

$256

CharlotteSan Diego

CLT - SAN

CLTSAN

Charlotte Douglas

Thu 10/16

2:24 pm-7:24 am

2 stops20h 00m

San Diego

Sun 10/19

7:47 pm-1:29 pm

2 stops14h 42m

$264

CharlotteSan Diego

CLT - SAN

CLTSAN

Charlotte Douglas

Thu 8/7

10:19 pm-3:59 pm

1 stop20h 40m

San Diego

Tue 8/12

6:25 am-4:36 pm

1 stop7h 11m

$265

SavannahSan Diego

SAV - SAN

SAVSAN

Savannah/Hilton Head

Wed 8/27

4:49 pm-5:56 pm

2 stops28h 07m

San Diego

Wed 9/3

1:17 pm-11:05 am

2 stops18h 48m

$286

CharlotteSan Diego

CLT - SAN

CLTSAN

Charlotte Douglas

Mon 9/22

5:20 pm-11:53 pm

1 stop9h 33m

San Diego

Thu 9/25

7:47 pm-1:44 pm

2 stops14h 57m

$289

AugustaSan Diego

AGS - SAN

AGSSAN

Augusta Bush Field

Sat 9/6

5:44 pm-9:15 pm

1 stop6h 31m

San Diego

Tue 9/9

6:25 am-5:04 pm

1 stop7h 39m

$297

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Sat 8/16

6:45 am-11:37 pm

3 stops19h 52m

San Diego

Wed 8/20

1:17 pm-1:13 pm

2 stops20h 56m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 60 results
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6

Best time to book a flight from South Carolina to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to San Diego

What is the cheapest month to book a flight from South Carolina to San Diego?

Currently, August is the cheapest month in which you can book a flight from South Carolina to San Diego (average of $286). Flying from South Carolina to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SAN?

Find hourly flight availability from South Carolina to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from South Carolina to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from South Carolina to San Diego, such as Alaska Airlines, Southwest, and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Food

7.1

Overall

8.0

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Food

7.1

Overall

8.0

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,246 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Food

7.1

Overall

8.0

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,981 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Food

7.1

Overall

8.0

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Breeze Airways
8.0
Very good
191 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Food

7.1

Overall

8.0

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,900 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Comfort

7.8

Crew

8.5

Food

7.1

Overall

8.0

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from South Carolina?

    San Diego (SAN) is the airport you will fly into if you book a flight from South Carolina to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • What are the cheapest airlines to fly from South Carolina to San Diego one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $92. Frontier flights start at $122 while deals on JetBlue start at $137 one-way.

  • What are the most popular routes from South Carolina to San Diego?

    The most popular flight routes from South Carolina to San Diego are Charlotte Douglas - San Diego, Savannah/Hilton Head - San Diego and Charleston - San Diego.

  • Can I find deals for flights from South Carolina to San Diego that include hotel bookings?

    Yes. In addition to deals on South Carolina to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to San Diego.

  • Can I find deals for business class flights from South Carolina to San Diego?

    Yes. Cheapflights offers flight deals from South Carolina to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to San Diego?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to San Diego (average of $286). Flying from South Carolina to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
Poway
National City
Lemon Grove
Imperial Beach
La Mesa
Alpine

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to San Diego

Discover the top 6 airlines that operate flights from South Carolina to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$112Average$353FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$170Average$299FlexibilityNo cancel feeOn-time62%
DeltaCheapest$257Average$438FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$484FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$268Average$441FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$336Average$471FlexibilityNo cancel feeOn-time63%

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