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$67+ Cheap flights from Iowa to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAN
Jun 17 — Jun 241
Wed 6/17
Wed 6/24
1 adult, Economy
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Cheap flight deals from Iowa to San Diego

Cheapest flights from Iowa to San Diego
Explore the most affordable flight options available from Iowa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:25 pm
OMA
-
SAN
1 stop14h 44m
Frontier
Wed 7/810:04 am
SAN
-
OMA
1 stop7h 16m
Frontier
Deal found 5/18$207
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:10 pm
CID
-
SAN
1 stop24h 48m
Multiple Airlines
Thu 8/209:53 pm
SAN
-
CID
1 stop18h 50m
Multiple Airlines
Deal found 5/15$208
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:15 pm
OMA
-
SAN
1 stop14h 50m
Frontier
Tue 7/219:53 pm
SAN
-
OMA
2 stops19h 27m
Frontier
Deal found 5/16$212
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:25 pm
OMA
-
SAN
1 stop14h 44m
Frontier
Mon 7/68:29 pm
SAN
-
OMA
2 stops20h 51m
Frontier
Deal found 5/18$216
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:15 pm
OMA
-
SAN
1 stop14h 54m
Frontier
Mon 6/229:43 am
SAN
-
OMA
2 stops31h 47m
Frontier
Deal found 5/17$222
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:19 pm
OMA
-
SAN
2 stops26h 39m
Frontier
Tue 8/259:37 am
SAN
-
OMA
1 stop7h 57m
Frontier
Deal found 5/13$224
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:01 pm
DSM
-
SAN
1 stop24h 57m
Multiple Airlines
Tue 7/144:17 pm
SAN
-
DSM
1 stop20h 15m
Multiple Airlines
Deal found 5/17$227
This Frontier deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
-
SAN
1 stop11h 37m
Frontier
Wed 7/86:25 am
SAN
-
DSM
1 stop5h 09m
Frontier
Deal found 5/17$228
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:14 pm
CID
-
SAN
2 stops19h 18m
Multiple Airlines
Thu 8/209:53 pm
SAN
-
CID
1 stop18h 50m
Multiple Airlines
Deal found 5/15$228
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/229:56 pm
DSM
-
SAN
1 stop12h 52m
Multiple Airlines
Tue 6/309:43 am
SAN
-
DSM
1 stop25h 16m
Multiple Airlines
Deal found 5/14$230
This Frontier deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:29 pm
OMA
-
SAN
1 stop5h 24m
Frontier
Wed 8/266:25 am
SAN
-
OMA
1 stop11h 09m
Frontier
Deal found 5/17$230
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:15 pm
OMA
-
SAN
1 stop14h 54m
Frontier
Mon 6/299:43 am
SAN
-
OMA
2 stops31h 47m
Frontier
Deal found 5/15$231

Find flight deals from Iowa to San Diego

Keep the following information in mind while searching for Iowa to San Diego flight deals. Data was last updated May 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$207
(Kiwi.com)

One-way from

$67
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$371
Provider with most accurate pricing for Des Moines-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-San Diego flights.
Search Deals
From Iowa to San Diego
Search Deals
One-way flight from Iowa to San Diego
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Iowa to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Fri 8/14

12:42 pm-6:06 pm

1 stop7h 24m

San Diego

Sun 8/16

10:30 pm-9:42 am

1 stop9h 12m

$277

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Fri 6/12

6:15 am-10:43 am

1 stop6h 28m

San Diego

Sat 6/20

6:15 am-6:58 pm

1 stop10h 43m

$298

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

Sat 8/8

5:09 pm-11:00 pm

1 stop7h 51m

San Diego

Wed 8/12

6:15 am-4:25 pm

1 stop8h 10m

$313

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

Sat 11/7

5:42 pm-9:57 pm

1 stop6h 15m

San Diego

Sat 11/14

9:55 pm-10:14 am

2 stops10h 19m

$318

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

Sat 8/8

5:09 pm-11:00 pm

1 stop7h 51m

San Diego

Mon 8/10

10:30 pm-10:25 am

1 stop9h 55m

$331

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

Sat 8/8

5:09 pm-11:00 pm

1 stop7h 51m

San Diego

Sun 8/9

10:30 pm-10:25 am

1 stop9h 55m

$331

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

Thu 9/3

11:00 am-6:23 pm

1 stop9h 23m

San Diego

Mon 9/7

10:40 pm-10:26 am

1 stop9h 46m

$349

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

Fri 5/29

5:56 am-11:16 am

1 stop7h 20m

San Diego

Wed 6/3

10:53 am-10:21 pm

1 stop9h 28m

$360

Cedar RapidsSan Diego

CID - SAN

CIDSAN

Cedar Rapids

Thu 5/28

5:45 am-12:38 pm

1 stop8h 53m

San Diego

Tue 6/2

3:30 pm-11:07 pm

1 stop5h 37m

$360

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Tue 6/16

12:25 pm-6:20 pm

2 stops7h 55m

San Diego

Tue 6/23

7:50 am-5:05 pm

2 stops7h 15m

$361

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/18

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Iowa to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to San Diego

How far ahead should I book a flight from Iowa to San Diego?

The best time to book flights from Iowa to San Diego is 27 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Iowa to San Diego?

Currently, June is the cheapest month in which you can book a flight from Iowa to San Diego (average of $82). Flying from Iowa to San Diego in January is currently the most expensive (average of $237). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Iowa to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Iowa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Iowa?

    San Diego (SAN) is the airport you will fly into if you book a flight from Iowa to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How popular is this Iowa to San Diego flight route?

    Within the past month, 1 users have taken a look at flights from Iowa to San Diego.

  • How long is the flight from Iowa to San Diego?

    A quick flight from Iowa to San Diego can take about 6h 15m. Delta provides one of the quickest options available for as low as $318. The distance from Iowa to San Diego is about 1580 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Iowa to San Diego one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $60. However, be on the lookout for offers from Frontier and Delta, as they are both options that can get you from Iowa to San Diego for a low price.

  • What are the most popular routes from Iowa to San Diego?

    The most popular route from Iowa to San Diego is Omaha Eppley Airfield - San Diego. You may also consider Cedar Rapids - San Diego or Des Moines - San Diego.

  • Can I find deals for flights from Iowa to San Diego that include hotel bookings?

    Yes. In addition to deals on Iowa to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to San Diego.

  • Can I find deals for business class flights from Iowa to San Diego?

    Yes. Cheapflights offers flight deals from Iowa to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to San Diego?

    Currently, June is the cheapest month in which you can book a flight from Iowa to San Diego (average of $82). Flying from Iowa to San Diego in January is currently the most expensive (average of $237). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
Poway
La Mesa
Julian
Lemon Grove

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Alternative routes for Iowa to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Iowa to San Diego

Discover the top 7 airlines that operate flights from Iowa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$100Average$268FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$101Average$154FlexibilityNo cancel feeOn-time88%
DeltaCheapest$118Average$351FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$253Average$395FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$258Average$405FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$303Average$474FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$458Average$458FlexibilityNo cancel feeOn-time75%

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