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$457+ Cheap flights from Greenville, NC to San Diego (PGV - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SAN
Dec 25 — Jan 11
Thu 12/25
Thu 1/1
1 adult, Economy
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Find flight deals from Greenville to San Diego

Best flights from Greenville to San Diego
Discover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 25, 2025.

This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/271:03 pmPGV - SAN
1 stop10h 33mAmerican Airlines
Sat 1/317:00 amSAN - PGV
1 stop8h 51mAmerican Airlines
Deal found 11/23$457
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/191:03 pmPGV - SAN
1 stop10h 33mAmerican Airlines
Sun 1/2512:40 pmSAN - PGV
1 stop7h 19mAmerican Airlines
Deal found 11/24$534

Cheap flight deals from Greenville to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 25, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$457
(American Airlines)
Provider with most accurate pricing for Pitt-Greenville-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Pitt-Greenville-San Diego flights.
Search Deals
From Pitt-Greenville to San Diego
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 25, 2025.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.

Fly from

Greenville

Fly to

San Diego

Route

Depart

Return

Price

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Tue 1/27

1:03 pm-8:36 pm

1 stop10h 33m

San Diego

Sat 1/31

7:00 am-6:51 pm

1 stop8h 51m

$457

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Mon 1/19

1:03 pm-8:36 pm

1 stop10h 33m

San Diego

Sun 1/25

12:40 pm-10:59 pm

1 stop7h 19m

$534

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Compare providers for flights from Greenville to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville, North Carolina-San Diego flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville, North Carolina-San Diego flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville, North Carolina-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville, North Carolina-San Diego flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville, North Carolina-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Diego

What is the cheapest month to book a flight from Greenville, North Carolina to San Diego?

Currently, August is the cheapest month in which you can book a flight from Greenville, North Carolina to San Diego (average of $139). Flying from Greenville, North Carolina to San Diego in December is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated November 25, 2025.
Get a feel of what it's like to fly with American Airlines from Greenville to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,038 reviews

Comfort

7.2

Boarding

7.5

Crew

8.0

Food

6.4

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.
American Airlines
7.2
Good
11,038 reviews
American Airlines
7.2
Good
11,038 reviews

Comfort

7.2

Boarding

7.5

Crew

8.0

Food

6.4

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2024

LHR - SAN

This was the best flight I have experienced in all the years I have been f doing this journey with BA. Flight, food and service A1. Well done BA.

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville, North Carolina to San Diego?

    A quick flight from Greenville, North Carolina to San Diego can take about 10h 33m. American Airlines provides one of the quickest options available for as low as $457. The distance from Greenville, North Carolina to San Diego is about 2268 mi.

  • What is the cheapest airline to fly from Greenville, North Carolina to San Diego round-trip?

    American Airlines, at $416, was found to be the cheapest airline from Greenville, North Carolina to San Diego..

  • Can I find deals for flights from Greenville to San Diego that include hotel bookings?

    Yes. In addition to deals on Greenville to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Diego.

  • Can I find deals for business class flights from Greenville to San Diego?

    Yes. Cheapflights offers flight deals from Greenville to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville, North Carolina to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Greenville, North Carolina to San Diego (average of $139). Flying from Greenville, North Carolina to San Diego in December is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

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Top airline flying from Greenville to San Diego

Discover the top airline that operate flights from Greenville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$416Average$516FlexibilityNo cancel feeOn-time71%

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