Menu

Cheap flights from Knoxville to San Francisco (TYS - SFO)

Know your dates, get live prices in seconds:

From
To
Depart
Return
Any month
Compare vs. Cheapflights |
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime
From
To
Depart
Depart
Time
Anytime

We work with more than 300 partners to bring you better travel deals

The best prices from Knoxville to San Francisco are usually found in August or July, booked 38 days in advance, depart on a Friday or Wednesday and return on a Saturday

How to find the cheapest flight from
Knoxville (TYS) to San Francisco (SFO)

TYS - SFO
Price
$319 - $507
SFO
Temperature
59 - 77 °F
SFO
Rainfall
0 - 4.7 inches

Popular in

January

High demand for flights, 20% potential price rise

Cheapest in

August

Best time to find cheap flights, 21% potential price drop

Round-trip from

$319

From Knoxville to San Francisco

One-way from

$276

One-way flight from Knoxville to San Francisco

Flight route prices based on searches on Cheapflights within the last 3 days, monthly prices based on aggregated historical data.
What is the cheapest day to fly round-trip from Knoxville to San Francisco?

Flights from Knoxville to San Francisco are found to be more expensive on Sunday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to San Francisco.

How far in advance should I book a flight from Knoxville to San Francisco?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 61 days in advance, which can save you up to 99% on flights from Knoxville to San Francisco compared to booking the week you need them. Waiting 61 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $416. For sooner than that we have options available in the next 3 days from $638.

When is the cheapest time to fly from Knoxville to San Francisco (TYS - SFO)?

When flying from Knoxville to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 15% versus a flight in the morning.

Cheap flights from Knoxville to San Francisco in November, December 2020

The best prices found for TYS to SFO flights for November, December
18 Dec - 21 Dec
$185pp
TYS
Knoxville McGhee Tyson
Multiple Airlines
   
2 STOPS
SFO
San Francisco
SFO
San Francisco
Frontier
 
1 STOP
TYS
Knoxville McGhee Tyson
11 Dec - 15 Dec
$199pp
TYS
Knoxville McGhee Tyson
Multiple Airlines
   
2 STOPS
SFO
San Francisco
SFO
San Francisco
Multiple Airlines
     
3 STOPS
TYS
Knoxville McGhee Tyson
18 Dec - 21 Dec
$202pp
TYS
Knoxville McGhee Tyson
Multiple Airlines
     
3 STOPS
SFO
San Francisco
SFO
San Francisco
Frontier
     
3 STOPS
TYS
Knoxville McGhee Tyson

Knoxville to San Francisco 2021 flight deals

Cheap flights to San Francisco from Knoxville found for next year
18 Dec - 21 Dec
$185pp
TYS
Knoxville McGhee Tyson
Multiple Airlines
   
2 STOPS
SFO
San Francisco
SFO
San Francisco
Frontier
 
1 STOP
TYS
Knoxville McGhee Tyson
11 Dec - 15 Dec
$199pp
TYS
Knoxville McGhee Tyson
Multiple Airlines
   
2 STOPS
SFO
San Francisco
SFO
San Francisco
Multiple Airlines
     
3 STOPS
TYS
Knoxville McGhee Tyson
18 Dec - 21 Dec
$202pp
TYS
Knoxville McGhee Tyson
Multiple Airlines
     
3 STOPS
SFO
San Francisco
SFO
San Francisco
Frontier
     
3 STOPS
TYS
Knoxville McGhee Tyson

Last minute flights from Knoxville to San Francisco

Late deals on round-trip flights to San Francisco from Knoxville, departing today and this week
3 Dec - 7 Dec
$294pp
TYS
Knoxville McGhee Tyson
United Airlines
 
1 STOP
SFO
San Francisco
SFO
San Francisco
United Airlines
 
1 STOP
TYS
Knoxville McGhee Tyson
3 Dec - 7 Dec
$334pp
TYS
Knoxville McGhee Tyson
United Airlines
 
1 STOP
SFO
San Francisco
SFO
San Francisco
United Airlines
 
1 STOP
TYS
Knoxville McGhee Tyson
3 Dec - 6 Dec
$456pp
TYS
Knoxville McGhee Tyson
United Airlines
 
1 STOP
SFO
San Francisco
SFO
San Francisco
United Airlines
 
1 STOP
TYS
Knoxville McGhee Tyson

One-way flights to San Francisco from Knoxville

The cheapest one-way flights from Knoxville to San Francisco
2:31 pm - 11:13 am
Frontier
1 Stop
23h 42m
TYS - SFO
Frontier
$276
Kiwi.com
4:05 am - 2:01 pm
American Airlines
2 Stops
12h 56m
TYS - SFO
American Airlines
1:30 am - 10:54 am
Delta
2 Stops
12h 24m
TYS - SFO
Delta
$313
Delta

Related info for your journey

Useful info, stats and facts about Knoxville to San Francisco flights.

Flight FAQs

From Knoxville to San Francisco

Are flight prices decreasing from Knoxville to San Francisco due to COVID-19 (coronavirus)?

At this time, Cheapflights has noticed price decreases for many domestic flights due to COVID-19. Travel is not necessarily recommended at this time, and flights may be prone to cancellation: please check with local authorities in both Knoxville and San Francisco for travel alerts, and be sure to review the airline's cancellation policy and travel advisories before booking. For more information, please view our post on what to know about COVID-19 (coronavirus) and travel.

What safety measures are being taken by airlines flying from Knoxville McGhee Tyson to San Francisco to control the spread of COVID-19?

Delta is one of the many airlines that have implemented additional safety measures to control the spread of COVID-19. Airline carriers are regularly disinfecting and sanitizing their aircraft. Masks are provided and are mandatory while on board. Pre-flight testing for symptoms and antibodies, alongside socially distanced seating (for a limited time) will work towards keeping travelers safer while flying from Knoxville McGhee Tyson to San Francisco. Policies will vary by airline.

Which airlines flying from Knoxville McGhee Tyson to San Francisco have flexible cancellations due to COVID-19?

Some of our airline partners flying from Knoxville McGhee Tyson to San Francisco have new flexible policies in place due to COVID-19. American Airlines, United Airlines, and Delta are some of the carriers where you may find flexible cancellation policies. You can use our site to filter for airlines like American Airlines with this kind of flexibility.

Can I find flights from Knoxville to San Francisco for under $200 on Cheapflights?

Yes, there are multiple flights from Knoxville to San Francisco for under $200. The cheapest flight booked recently is on Frontier for just $153, but on average you can expect to pay $228.

Are there nonstop flights from Knoxville to San Francisco for under $200 on Cheapflights?

There are no nonstop flights from Knoxville to San Francisco, but Cheapflights can provide you with all the information you need to find the fastest route with the fewest stops.

Are there last-minute flights available from Knoxville to San Francisco for under $300?

There are currently 6+ open flights from Knoxville to San Francisco within the next 7 days for less than $300.

Does it rain more in Knoxville or San Francisco?

Expected rainfall in Knoxville is less than in San Francisco. You can expect this to be the case over the next 11 days.

Is Knoxville weather warmer or cooler than San Francisco?

We forecast the temperature to be around the 90 °F's in July, on average. The temperature in San Francisco is generally colder than in Knoxville. Book flights in a timely manner in correlation to your departure date.

How long is the flight from Knoxville to San Francisco?

A quick flight from Knoxville to San Francisco can take about 7h 21m. Frontier provides one of the quickest options available for as low as $193. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Knoxville to San Francisco round-trip?

Flying on Frontier is currently your cheapest option to San Francisco, with prices starting at $153. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $294 and $315, respectively. These flights start at 62% lower than the current average price 3 months from now.

What are the cheapest airlines to fly from Knoxville to San Francisco one-way?

One-way options have recently been found by users for as low as $34 on Frontier. Other airlines that offer cheap prices include United Airlines from $157 and American Airlines from $188 one-way.

Alternative routes for Knoxville to San Francisco

Destination information for San Francisco

Things to know before you go. Useful info for your trip from Knoxville to San Francisco
Average temperature for November in San Francisco
64.4 °F
Avg rainfall for November in San Francisco
1.7 ″

Airports servicing Knoxville

Airports servicing San Francisco

Top 4 airlines from Knoxville to San Francisco

The chart below displays the airlines Cheapflights users traveling from Knoxville to San Francisco choose most often. Cheapest and average prices are based on aggregated data from the past 12 months.

Airline Cheapest Average Flexibility On-time COVID-19 safety
Frontier
$106 $266 No cancel fee 62%
Delta
$222 $467 No cancel fee N/A
United Airlines
$318 $471 No cancel fee 69%
American Airlines
$296 $476 No cancel fee 71%
Home North America USA California San Francisco Cheap flights from Knoxville to San Francisco