$142+ Cheap flights from San Francisco to Knoxville (SFO - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — TYS
Sep 1 — Sep 81
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Francisco to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Francisco to KnoxvilleExplore the most affordable flight options available from San Francisco to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.
Explore the most affordable flight options available from San Francisco to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:06 pm
SFO
- TYS
1 stop14h 32m
Multiple Airlines
Thu 10/229:29 pm
TYS
- SFO
1 stop13h 54m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:06 pm
SFO
- TYS
1 stop14h 32m
Multiple Airlines
Mon 10/199:59 pm
TYS
- SFO
1 stop18h 22m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:25 am
SFO
- TYS
1 stop12h 24m
Multiple Airlines
Mon 11/29:42 pm
TYS
- SFO
1 stop15h 47m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:00 am
SFO
- TYS
1 stop7h 46m
Multiple Airlines
Fri 8/288:30 am
TYS
- SFO
2 stops37h 15m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:06 pm
SFO
- TYS
1 stop14h 32m
Multiple Airlines
Fri 10/231:04 pm
TYS
- SFO
2 stops30h 53m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:28 pm
SFO
- TYS
2 stops19h 59m
Multiple Airlines
Sun 9/137:00 am
TYS
- SFO
1 stop20h 14m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:25 am
SFO
- TYS
1 stop11h 18m
Multiple Airlines
Sun 11/812:29 pm
TYS
- SFO
1 stop23h 13m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:42 pm
SFO
- TYS
2 stops37h 29m
Multiple Airlines
Sun 11/16:30 am
TYS
- SFO
1 stop7h 46m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$302
Best flights from San Francisco to KnoxvilleDiscover carefully curated flight deals from San Francisco to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 2, 2026.
Discover carefully curated flight deals from San Francisco to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 2, 2026.
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:30 pm
SFO
- TYS
1 stop6h 59m
Delta
Mon 9/287:25 pm
TYS
- SFO
1 stop7h 32m
Delta
Deal found 7/29![Delta logo]()
$363
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:00 am
SFO
- TYS
2 stops9h 50m
Southwest
Tue 10/65:15 pm
TYS
- SFO
2 stops8h 30m
Southwest
Deal found 7/29![Southwest logo]()
$378
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:35 pm
SFO
- TYS
1 stop8h 22m
United Airlines
Thu 8/271:00 pm
TYS
- SFO
1 stop11h 28m
United Airlines
Deal found 8/1![United Airlines logo]()
$499
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:40 am
SFO
- TYS
2 stops10h 15m
Southwest
Mon 8/315:45 pm
TYS
- SFO
1 stop7h 10m
Southwest
Deal found 7/30![Southwest logo]()
$392
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:40 pm
SFO
- TYS
2 stops9h 25m
Southwest
Fri 8/282:05 pm
TYS
- SFO
2 stops9h 30m
Southwest
Deal found 7/30![Southwest logo]()
$406
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:30 pm
SFO
- TYS
1 stop9h 24m
Delta
Tue 10/205:18 pm
TYS
- SFO
1 stop8h 10m
Delta
Deal found 7/28![Delta logo]()
$451
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:00 pm
SFO
- TYS
1 stop8h 36m
Delta
Fri 8/2810:28 am
TYS
- SFO
1 stop7h 19m
Delta
Deal found 7/29![Delta logo]()
$454
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:35 am
SFO
- TYS
2 stops10h 05m
Southwest
Tue 10/208:20 am
TYS
- SFO
1 stop9h 15m
Southwest
Deal found 7/28![Southwest logo]()
$450
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:59 pm
SFO
- TYS
2 stops9h 45m
Delta
Sat 9/55:00 pm
TYS
- SFO
1 stop9h 58m
Delta
Deal found 8/2![Delta logo]()
$470
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:50 am
SFO
- TYS
1 stop6h 25m
Southwest
Tue 12/14:15 pm
TYS
- SFO
1 stop8h 55m
Southwest
Deal found 7/31![Southwest logo]()
$469
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:55 pm
SFO
- TYS
1 stop9h 49m
Delta
Sat 9/264:03 pm
TYS
- SFO
1 stop6h 55m
Delta
Deal found 7/29![Delta logo]()
$475
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:00 am
SFO
- TYS
2 stops8h 35m
Southwest
Fri 9/42:05 pm
TYS
- SFO
2 stops10h 25m
Southwest
Deal found 7/31![Southwest logo]()
$478
Last-minute flights from San Francisco to KnoxvilleDiscover last-minute flight deals from San Francisco to Knoxville. Data last updated August 2, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Knoxville. Data last updated August 2, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Mon 8/178:19 pm
TYS
- SFO
1 stop6h 59m
Frontier
Deal found 7/29![Frontier logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:56 pm
SFO
- TYS
2 stops37h 53m
Multiple Airlines
Mon 8/314:48 pm
TYS
- SFO
1 stop20h 37m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:38 pm
SFO
- TYS
1 stop27h 08m
Multiple Airlines
Mon 8/2412:54 pm
TYS
- SFO
1 stop10h 02m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:00 am
SFO
- TYS
1 stop7h 46m
Multiple Airlines
Mon 8/248:30 am
TYS
- SFO
2 stops11h 06m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:00 am
SFO
- TYS
1 stop7h 46m
Multiple Airlines
Sun 8/232:39 pm
TYS
- SFO
1 stop28h 17m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:00 am
SFO
- TYS
1 stop7h 46m
Multiple Airlines
Fri 8/288:30 am
TYS
- SFO
2 stops37h 15m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:38 pm
SFO
- TYS
1 stop27h 08m
Multiple Airlines
Thu 9/32:34 pm
TYS
- SFO
1 stop28h 22m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:07 pm
SFO
- TYS
2 stops45h 42m
Multiple Airlines
Fri 9/49:44 pm
TYS
- SFO
1 stop25h 12m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$339
One-way flights from San Francisco to KnoxvilleSearch for one-way flight options from San Francisco to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 2, 2026.
Search for one-way flight options from San Francisco to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 2, 2026.
This Priceline deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
SFO
- TYS
1 stop10h 24m
Frontier
Deal found 7/29![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:15 pm
SFO
- TYS
1 stop28h 46m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:56 pm
SFO
- TYS
2 stops22h 56m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:05 pm
SFO
- TYS
2 stops33h 00m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:59 pm
SFO
- TYS
1 stop18h 55m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:31 pm
SFO
- TYS
2 stops50h 34m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:05 pm
SFO
- TYS
2 stops34h 06m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:20 am
SFO
- TYS
2 stops23h 24m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$178
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:02 am
SFO
- TYS
1 stop9h 20m
American Airlines
Deal found 8/2![American Airlines logo]()
$182
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:59 pm
SFO
- TYS
1 stop8h 19m
Delta
Deal found 7/30![Delta logo]()
$183
Find flight deals from San Francisco to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $253 (Kiwi.com) |
One-way from | $142 (Priceline) |
Popular in | May |
Cheapest in | February |
Average price | $437 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
Use the filters below to find and compare flights from San Francisco to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Mon 9/21
11:30 pm-9:29 am
1 stop6h 59m
Knoxville McGhee Tyson
Mon 9/28
7:25 pm-11:57 pm
1 stop7h 32m
$363
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Sat 10/3
5:00 am-5:50 pm
2 stops9h 50m
Knoxville McGhee Tyson
Tue 10/6
5:15 pm-10:45 pm
2 stops8h 30m
$378
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Tue 8/18
5:40 am-6:55 pm
2 stops10h 15m
Knoxville McGhee Tyson
Mon 8/31
5:45 pm-9:55 pm
1 stop7h 10m
$392
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Mon 8/24
11:40 pm-12:05 pm
2 stops9h 25m
Knoxville McGhee Tyson
Fri 8/28
2:05 pm-8:35 pm
2 stops9h 30m
$406
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Fri 10/16
9:35 am-10:40 pm
2 stops10h 05m
Knoxville McGhee Tyson
Tue 10/20
8:20 am-2:35 pm
1 stop9h 15m
$450
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Thu 10/15
10:30 pm-10:54 am
1 stop9h 24m
Knoxville McGhee Tyson
Tue 10/20
5:18 pm-10:28 pm
1 stop8h 10m
$451
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Mon 8/24
10:00 pm-9:36 am
1 stop8h 36m
Knoxville McGhee Tyson
Fri 8/28
10:28 am-2:47 pm
1 stop7h 19m
$454
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Thu 11/26
8:50 am-6:15 pm
1 stop6h 25m
Knoxville McGhee Tyson
Tue 12/1
4:15 pm-10:10 pm
1 stop8h 55m
$469
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Sat 8/29
8:59 pm-9:44 am
2 stops9h 45m
Knoxville McGhee Tyson
Sat 9/5
5:00 pm-11:58 pm
1 stop9h 58m
$470
San FranciscoKnoxville
SFO - TYS
SFOTYS
San Francisco
Fri 9/25
9:55 pm-10:44 am
1 stop9h 49m
Knoxville McGhee Tyson
Sat 9/26
4:03 pm-7:58 pm
1 stop6h 55m
$475
Showing 1-10 of 24 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Knoxville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Francisco with our price prediction graph.
SFO-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Knoxville
How far ahead should I book a flight from San Francisco to Knoxville?
Booking 61 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Francisco to Knoxville?
Currently, February is the cheapest month in which you can book a flight from San Francisco to Knoxville (average of $409). Flying from San Francisco to Knoxville in May is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Knoxville?
Airfare is below average for this route at the moment.
San Francisco to Knoxville flights typically cost between $388 and $483 in October.The cheapest round-trip price found within the last 5 days was $253 on Multiple Airlines (Oct 18-Oct 22).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 2, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from San Francisco to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from San Francisco
Popular flights
Alternative routes for San Francisco to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to Knoxville by cabin class
Find flights from San Francisco to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 2, 2026.
San Francisco and Knoxville flights
Browse other San Francisco and Knoxville flight options. Last updated on August 2, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on August 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Francisco to Knoxville
Discover the top 4 airlines that operate flights from San Francisco to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$89 | Average$334 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$328 | Average$479 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$523 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$329 | Average$537 | FlexibilityNo cancel fee | On-time69% |