$113+ Cheap flights from San Diego to Knoxville (SAN - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — TYS
Aug 20 — Aug 271
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Knoxville
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Best
Last-minute
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Cheapest flights from San Diego to KnoxvilleExplore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 21, 2026.
Explore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:25 am
SAN
- TYS
1 stop13h 27m
Multiple Airlines
Sun 8/237:00 am
TYS
- SAN
1 stop29h 05m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:25 am
SAN
- TYS
1 stop13h 27m
Multiple Airlines
Mon 8/318:00 am
TYS
- SAN
2 stops15h 14m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:57 am
SAN
- TYS
1 stop9h 13m
Multiple Airlines
Sun 11/16:30 am
TYS
- SAN
1 stop12h 11m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:45 pm
SAN
- TYS
1 stop27h 52m
Multiple Airlines
Sun 8/162:51 pm
TYS
- SAN
1 stop27h 52m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:45 pm
SAN
- TYS
1 stop19h 04m
Multiple Airlines
Sun 8/237:00 am
TYS
- SAN
1 stop29h 05m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$284
This Expedia deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:25 am
SAN
- TYS
1 stop9h 59m
Frontier
Mon 8/178:19 pm
TYS
- SAN
1 stop15h 46m
Frontier
Deal found 7/16![Frontier logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:51 pm
SAN
- TYS
1 stop14h 06m
Multiple Airlines
Thu 8/202:39 pm
TYS
- SAN
1 stop12h 05m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:51 pm
SAN
- TYS
2 stops19h 33m
Multiple Airlines
Sun 8/237:00 am
TYS
- SAN
1 stop29h 05m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:28 pm
SAN
- TYS
1 stop27h 59m
Multiple Airlines
Wed 8/122:25 pm
TYS
- SAN
2 stops28h 18m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$299
Best flights from San Diego to KnoxvilleDiscover carefully curated flight deals from San Diego to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 21, 2026.
Discover carefully curated flight deals from San Diego to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:28 pm
SAN
- TYS
2 stops27h 16m
Multiple Airlines
Thu 8/202:39 pm
TYS
- SAN
1 stop12h 05m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:40 am
SAN
- TYS
2 stops8h 55m
Southwest
Thu 8/205:45 pm
TYS
- SAN
1 stop8h 40m
Southwest
Deal found 7/16![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:00 am
SAN
- TYS
1 stop9h 10m
Delta
Sat 9/194:03 pm
TYS
- SAN
1 stop8h 16m
Delta
Deal found 7/20![Delta logo]()
$378
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:25 am
SAN
- TYS
2 stops8h 30m
Southwest
Tue 8/253:00 pm
TYS
- SAN
2 stops8h 55m
Southwest
Deal found 7/16![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:17 pm
SAN
- TYS
1 stop9h 03m
Delta
Tue 8/254:38 pm
TYS
- SAN
1 stop9h 22m
Delta
Deal found 7/19![Delta logo]()
$383
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:50 am
SAN
- TYS
2 stops7h 45m
Southwest
Tue 8/253:00 pm
TYS
- SAN
2 stops9h 05m
Southwest
Deal found 7/20![Southwest logo]()
$394
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:25 pm
SAN
- TYS
1 stop8h 11m
Delta
Thu 9/101:31 pm
TYS
- SAN
1 stop8h 55m
Delta
Deal found 7/20![Delta logo]()
$406
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:50 am
SAN
- TYS
2 stops7h 45m
Southwest
Mon 8/175:45 pm
TYS
- SAN
2 stops7h 10m
Southwest
Deal found 7/16![Southwest logo]()
$417
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:30 am
SAN
- TYS
1 stop7h 04m
Delta
Tue 8/187:30 am
TYS
- SAN
1 stop8h 03m
Delta
Deal found 7/19![Delta logo]()
$436
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:40 pm
SAN
- TYS
1 stop10h 20m
Southwest
Mon 10/1912:50 pm
TYS
- SAN
1 stop10h 40m
Southwest
Deal found 7/20![Southwest logo]()
$439
Last-minute flights from San Diego to KnoxvilleDiscover last-minute flight deals from San Diego to Knoxville. Data last updated July 21, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Knoxville. Data last updated July 21, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:25 am
SAN
- TYS
1 stop9h 59m
Frontier
Wed 8/128:19 pm
TYS
- SAN
1 stop6h 32m
Frontier
Deal found 7/18![Frontier logo]()
$325
This CheapOair deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:25 am
SAN
- TYS
1 stop9h 59m
Frontier
Mon 8/108:19 pm
TYS
- SAN
1 stop15h 51m
Frontier
Deal found 7/17![Frontier logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:28 pm
SAN
- TYS
1 stop27h 59m
Multiple Airlines
Wed 8/122:25 pm
TYS
- SAN
2 stops28h 18m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:45 pm
SAN
- TYS
1 stop27h 52m
Multiple Airlines
Sun 8/162:51 pm
TYS
- SAN
1 stop27h 52m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:51 pm
SAN
- TYS
1 stop14h 06m
Multiple Airlines
Thu 8/202:39 pm
TYS
- SAN
1 stop12h 05m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$290
This Expedia deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:25 am
SAN
- TYS
1 stop9h 59m
Frontier
Mon 8/178:19 pm
TYS
- SAN
1 stop15h 46m
Frontier
Deal found 7/16![Frontier logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:51 pm
SAN
- TYS
2 stops19h 33m
Multiple Airlines
Sun 8/237:00 am
TYS
- SAN
1 stop29h 05m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:25 am
SAN
- TYS
1 stop13h 27m
Multiple Airlines
Mon 8/318:00 am
TYS
- SAN
2 stops15h 14m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$247
One-way flights from San Diego to KnoxvilleSearch for one-way flight options from San Diego to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 21, 2026.
Search for one-way flight options from San Diego to Knoxville. Find affordable one-way fares based on user searches. Data last updated July 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:25 am
SAN
- TYS
1 stop27h 46m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:25 am
SAN
- TYS
1 stop13h 28m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:32 pm
SAN
- TYS
1 stop14h 12m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$136
This Priceline deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:25 am
SAN
- TYS
1 stop9h 59m
Frontier
Deal found 7/21![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:32 pm
SAN
- TYS
1 stop13h 39m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:32 pm
SAN
- TYS
1 stop13h 39m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$160
This WAYA deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:09 pm
SAN
- TYS
1 stop7h 28m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:25 am
SAN
- TYS
3 stops53h 06m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:24 pm
SAN
- TYS
1 stop16h 34m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:24 pm
SAN
- TYS
2 stops42h 54m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$172
Find flight deals from San Diego to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $247 (Kiwi.com) |
One-way from | $113 (Kiwi.com) |
Popular in | November |
Cheapest in | May |
Average price | $456 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 21, 2026.
Use the filters below to find and compare flights from San Diego to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Thu 8/13
4:28 pm-10:44 pm
2 stops27h 16m
Knoxville McGhee Tyson
Thu 8/20
2:39 pm-11:44 pm
1 stop12h 05m
$308
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Thu 8/13
6:40 am-6:35 pm
2 stops8h 55m
Knoxville McGhee Tyson
Thu 8/20
5:45 pm-11:25 pm
1 stop8h 40m
$360
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 8/18
7:25 am-6:55 pm
2 stops8h 30m
Knoxville McGhee Tyson
Tue 8/25
3:00 pm-8:55 pm
2 stops8h 55m
$366
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 9/1
8:00 am-8:10 pm
1 stop9h 10m
Knoxville McGhee Tyson
Sat 9/19
4:03 pm-9:19 pm
1 stop8h 16m
$378
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Mon 8/17
10:17 pm-10:20 am
1 stop9h 03m
Knoxville McGhee Tyson
Tue 8/25
4:38 pm-11:00 pm
1 stop9h 22m
$383
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Mon 8/17
7:50 am-6:35 pm
2 stops7h 45m
Knoxville McGhee Tyson
Tue 8/25
3:00 pm-9:05 pm
2 stops9h 05m
$394
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Mon 8/31
10:25 pm-9:36 am
1 stop8h 11m
Knoxville McGhee Tyson
Thu 9/10
1:31 pm-7:26 pm
1 stop8h 55m
$406
Quickest round-trip
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Fri 8/14
7:50 am-6:35 pm
2 stops7h 45m
Knoxville McGhee Tyson
Mon 8/17
5:45 pm-9:55 pm
2 stops7h 10m
$417
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Fri 8/14
11:30 am-9:34 pm
1 stop7h 04m
Knoxville McGhee Tyson
Tue 8/18
7:30 am-12:33 pm
1 stop8h 03m
$436
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Fri 10/16
10:40 pm-12:00 pm
1 stop10h 20m
Knoxville McGhee Tyson
Mon 10/19
12:50 pm-8:30 pm
1 stop10h 40m
$439
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Diego to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Knoxville in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Diego with our price prediction graph.
SAN-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Knoxville
Prices
Delays
How far ahead should I book a flight from San Diego to Knoxville?
Booking 32 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Knoxville?
Currently, May is the cheapest month in which you can book a flight from San Diego to Knoxville (average of $414). Flying from San Diego to Knoxville in November is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Knoxville?
How often are flights from San Diego to Knoxville delayed?
About 0% of weekly flights between San Diego and Knoxville have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for San Diego to Knoxville flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated July 21, 2026.
See what other customers who have flown with Alaska Airlines,Delta, andUnited Airlines from San Diego to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.1
Overall
7.9
Entertainment
7.0
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.1
Overall
7.9
Entertainment
7.0
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.1
Overall
7.9
Entertainment
7.0
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.1
Overall
7.9
Entertainment
7.0
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.1
Overall
7.9
Entertainment
7.0
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.1
Overall
7.9
Entertainment
7.0
Reviews
1 / 20
2.0
MediocreArt,Dec 2025
SAN - OGG
Related info for your journey
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Top 5 airlines flying from San Diego to Knoxville
Discover the top 5 airlines that operate flights from San Diego to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$65 | Average$270 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$276 | Average$476 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$474 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$282 | Average$474 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$496 | Average$785 | FlexibilityNo cancel fee | On-time75% |