$106+ Cheap flights from San Diego to Knoxville (SAN - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — TYS
May 24 — May 311
Round-trip
1 adult, Economy
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Cheapest flights from San Diego to KnoxvilleExplore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
Explore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:38 pm
SAN
- TYS
1 stop6h 40m
American Airlines
Sat 9/197:15 am
TYS
- SAN
1 stop6h 41m
American Airlines
Deal found 4/21![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:29 pm
SAN
- TYS
1 stop30h 51m
Multiple Airlines
Mon 5/118:32 pm
TYS
- SAN
1 stop30h 18m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:30 am
SAN
- TYS
1 stop8h 25m
Southwest
Tue 8/257:00 am
TYS
- SAN
1 stop6h 10m
Southwest
Deal found 4/21![Southwest logo]()
$254
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:25 am
SAN
- TYS
1 stop10h 08m
Frontier
Mon 6/88:32 pm
TYS
- SAN
1 stop19h 01m
Frontier
Deal found 4/23![Frontier logo]()
$261
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:57 pm
SAN
- TYS
1 stop7h 57m
United Airlines
Tue 6/26:30 am
TYS
- SAN
1 stop7h 51m
United Airlines
Deal found 4/21![United Airlines logo]()
$265
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:28 pm
SAN
- TYS
1 stop9h 08m
American Airlines
Tue 6/95:33 pm
TYS
- SAN
1 stop8h 06m
American Airlines
Deal found 4/21![American Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:25 am
SAN
- TYS
1 stop10h 12m
Multiple Airlines
Sun 6/287:00 am
TYS
- SAN
1 stop29h 09m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:50 pm
SAN
- TYS
1 stop7h 11m
Delta
Sat 5/305:35 pm
TYS
- SAN
1 stop8h 53m
Delta
Deal found 4/23![Delta logo]()
$277
This CheapOair deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:37 am
SAN
- TYS
1 stop7h 00m
Frontier
Mon 8/108:32 pm
TYS
- SAN
1 stop15h 10m
Frontier
Deal found 4/19![Frontier logo]()
$281
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:50 am
SAN
- TYS
1 stop7h 47m
American Airlines
Fri 6/58:11 pm
TYS
- SAN
1 stop6h 48m
American Airlines
Deal found 4/21![American Airlines logo]()
$286
Best flights from San Diego to KnoxvilleDiscover carefully curated flight deals from San Diego to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
Discover carefully curated flight deals from San Diego to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:50 pm
SAN
- TYS
1 stop7h 11m
Delta
Sat 5/305:35 pm
TYS
- SAN
1 stop8h 53m
Delta
Deal found 4/23![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:28 pm
SAN
- TYS
2 stops12h 40m
United Airlines
Sat 9/194:56 pm
TYS
- SAN
1 stop8h 31m
United Airlines
Deal found 4/22![United Airlines logo]()
$370
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:20 am
SAN
- TYS
2 stops8h 20m
Southwest
Tue 8/1112:45 pm
TYS
- SAN
1 stop9h 05m
Southwest
Deal found 4/20![Southwest logo]()
$371
This Alaska Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:15 am
SAN
- TYS
2 stops12h 38m
Alaska Airlines
Sat 9/191:40 pm
TYS
- SAN
2 stops23h 25m
Alaska Airlines
Deal found 4/20![Alaska Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:30 pm
SAN
- TYS
1 stop8h 06m
Delta
Wed 7/293:54 pm
TYS
- SAN
1 stop6h 41m
Delta
Deal found 4/20![Delta logo]()
$388
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:35 am
SAN
- TYS
1 stop6h 18m
United Airlines
Wed 6/31:54 pm
TYS
- SAN
2 stops8h 57m
United Airlines
Deal found 4/19![United Airlines logo]()
$415
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/301:50 pm
SAN
- TYS
1 stop7h 11m
Delta
Fri 6/55:40 am
TYS
- SAN
1 stop7h 03m
Delta
Deal found 4/19![Delta logo]()
$397
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:40 pm
SAN
- TYS
1 stop8h 26m
United Airlines
Tue 5/125:55 pm
TYS
- SAN
1 stop7h 44m
United Airlines
Deal found 4/23![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:32 pm
SAN
- TYS
2 stops10h 33m
United Airlines
Sat 5/301:54 pm
TYS
- SAN
2 stops13h 00m
United Airlines
Deal found 4/23![United Airlines logo]()
$463
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:32 pm
SAN
- TYS
2 stops10h 33m
United Airlines
Fri 6/55:45 am
TYS
- SAN
1 stop7h 53m
United Airlines
Deal found 4/23![United Airlines logo]()
$478
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:45 pm
SAN
- TYS
1 stop9h 57m
United Airlines
Fri 6/56:30 am
TYS
- SAN
1 stop7h 51m
United Airlines
Deal found 4/20![United Airlines logo]()
$485
Last-minute flights from San Diego to KnoxvilleDiscover last-minute flight deals from San Diego to Knoxville. Data last updated April 24, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Knoxville. Data last updated April 24, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:25 am
SAN
- TYS
1 stop10h 08m
Multiple Airlines
Mon 5/111:43 pm
TYS
- SAN
1 stop10h 21m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:29 pm
SAN
- TYS
1 stop30h 51m
Multiple Airlines
Mon 5/118:32 pm
TYS
- SAN
1 stop30h 18m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:25 am
SAN
- TYS
2 stops30h 10m
Multiple Airlines
Fri 5/151:43 pm
TYS
- SAN
1 stop10h 21m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:50 pm
SAN
- TYS
1 stop7h 11m
Delta
Sat 5/305:35 pm
TYS
- SAN
1 stop8h 53m
Delta
Deal found 4/23![Delta logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:37 am
SAN
- TYS
1 stop25h 22m
Multiple Airlines
Sat 5/306:00 am
TYS
- SAN
2 stops32h 24m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:40 pm
SAN
- TYS
1 stop8h 25m
United Airlines
Wed 6/35:57 pm
TYS
- SAN
1 stop7h 37m
United Airlines
Deal found 4/19![United Airlines logo]()
$337
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:57 pm
SAN
- TYS
1 stop7h 57m
United Airlines
Tue 6/26:30 am
TYS
- SAN
1 stop7h 51m
United Airlines
Deal found 4/21![United Airlines logo]()
$265
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:15 am
SAN
- TYS
1 stop8h 12m
Delta
Tue 6/211:44 am
TYS
- SAN
1 stop9h 17m
Delta
Deal found 4/20![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:50 am
SAN
- TYS
1 stop7h 47m
American Airlines
Fri 6/58:11 pm
TYS
- SAN
1 stop6h 48m
American Airlines
Deal found 4/21![American Airlines logo]()
$286
One-way flights from San Diego to KnoxvilleSearch for one-way flight options from San Diego to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
Search for one-way flight options from San Diego to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
This Priceline deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:25 am
SAN
- TYS
1 stop10h 08m
Frontier
Deal found 4/22![Frontier logo]()
$106
This Expedia deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:25 am
SAN
- TYS
1 stop6h 08m
Frontier
Deal found 4/20![Frontier logo]()
$125
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:57 pm
SAN
- TYS
1 stop7h 57m
United Airlines
Deal found 4/21![United Airlines logo]()
$133
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:33 am
SAN
- TYS
1 stop6h 52m
Delta
Deal found 4/20![Delta logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:29 pm
SAN
- TYS
1 stop30h 51m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$143
This Priceline deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/79:37 am
SAN
- TYS
1 stop7h 00m
Frontier
Deal found 4/19![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:38 pm
SAN
- TYS
3 stops29h 23m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/39:43 am
SAN
- TYS
2 stops48h 11m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:25 am
SAN
- TYS
2 stops38h 12m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:17 pm
SAN
- TYS
1 stop27h 39m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$159
Find flight deals from San Diego to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (American Airlines) |
One-way from | $106 (Priceline) |
Popular in | November |
Cheapest in | September |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from San Diego to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 5/23
1:50 pm-12:01 am
1 stop7h 11m
Knoxville McGhee Tyson
Sat 5/30
5:35 pm-11:28 pm
1 stop8h 53m
$277
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 9/1
6:28 pm-10:08 am
2 stops12h 40m
Knoxville McGhee Tyson
Sat 9/19
4:56 pm-10:27 pm
1 stop8h 31m
$370
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 8/8
6:20 am-5:40 pm
2 stops8h 20m
Knoxville McGhee Tyson
Tue 8/11
12:45 pm-6:50 pm
1 stop9h 05m
$371
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 7/25
10:30 pm-9:36 am
1 stop8h 06m
Knoxville McGhee Tyson
Wed 7/29
3:54 pm-7:35 pm
1 stop6h 41m
$388
Quickest round-trip
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 5/30
1:50 pm-12:01 am
1 stop7h 11m
Knoxville McGhee Tyson
Fri 6/5
5:40 am-9:43 am
1 stop7h 03m
$397
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 5/26
6:35 am-3:53 pm
1 stop6h 18m
Knoxville McGhee Tyson
Wed 6/3
1:54 pm-7:51 pm
2 stops8h 57m
$415
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 9/1
6:15 am-9:53 pm
2 stops12h 38m
Knoxville McGhee Tyson
Sat 9/19
1:40 pm-10:05 am
2 stops23h 25m
$447
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Fri 5/8
10:40 pm-10:06 am
1 stop8h 26m
Knoxville McGhee Tyson
Tue 5/12
5:55 pm-10:39 pm
1 stop7h 44m
$449
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 5/23
8:32 pm-10:05 am
2 stops10h 33m
Knoxville McGhee Tyson
Sat 5/30
1:54 pm-11:54 pm
2 stops13h 00m
$463
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 5/30
8:32 pm-10:05 am
2 stops10h 33m
Knoxville McGhee Tyson
Fri 6/5
5:45 am-10:38 am
1 stop7h 53m
$478
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from San Diego to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Knoxville in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Diego with our price prediction graph.
SAN-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Knoxville
Prices
Delays
How far ahead should I book a flight from San Diego to Knoxville?
Booking 32 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Knoxville?
Currently, September is the cheapest month in which you can book a flight from San Diego to Knoxville (average of $292). Flying from San Diego to Knoxville in November is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Knoxville?
How often are flights from San Diego to Knoxville delayed?
About 0% of weekly flights between San Diego and Knoxville have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for San Diego to Knoxville flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 24, 2026.
See what other customers who have flown with Alaska Airlines,Delta, andUnited Airlines from San Diego to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.0
Boarding
8.1
Overall
7.9
Food
7.0
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Overall
7.9
Food
7.0
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Overall
7.9
Food
7.0
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Overall
7.9
Food
7.0
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Overall
7.9
Food
7.0
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Entertainment
7.0
Boarding
8.1
Overall
7.9
Food
7.0
Crew
8.5
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Related info for your journey
Find useful and relevant information for your journey from San Diego to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 24, 2026.
San Diego and Knoxville flights
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Top 5 airlines flying from San Diego to Knoxville
Discover the top 5 airlines that operate flights from San Diego to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$65 | Average$270 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$276 | Average$431 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$439 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$417 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$496 | Average$798 | FlexibilityNo cancel fee | On-time75% |