$111+ Cheap flights from San Diego to Knoxville (SAN - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — TYS
Jun 10 — Jun 171
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Knoxville
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Cheapest flights from San Diego to KnoxvilleExplore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
Explore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:25 am
SAN
- TYS
1 stop10h 12m
Frontier
Wed 6/178:32 pm
TYS
- SAN
1 stop15h 37m
Frontier
Deal found 5/11![Frontier logo]()
$220
This CheapOair deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:25 am
SAN
- TYS
1 stop10h 11m
Frontier
Fri 7/318:32 pm
TYS
- SAN
1 stop15h 33m
Frontier
Deal found 5/9![Frontier logo]()
$240
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:25 am
SAN
- TYS
1 stop10h 12m
Frontier
Fri 6/268:32 pm
TYS
- SAN
1 stop15h 10m
Frontier
Deal found 5/7![Frontier logo]()
$260
This Priceline deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/259:37 am
SAN
- TYS
1 stop6h 47m
Frontier
Fri 5/298:19 pm
TYS
- SAN
1 stop6h 31m
Frontier
Deal found 5/9![Frontier logo]()
$270
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:25 am
SAN
- TYS
1 stop10h 11m
Frontier
Mon 8/108:32 pm
TYS
- SAN
1 stop15h 33m
Frontier
Deal found 5/10![Frontier logo]()
$274
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:25 am
SAN
- TYS
1 stop10h 12m
Frontier
Mon 6/228:32 pm
TYS
- SAN
1 stop15h 37m
Frontier
Deal found 5/11![Frontier logo]()
$280
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:37 am
SAN
- TYS
1 stop6h 56m
Frontier
Wed 6/108:32 pm
TYS
- SAN
1 stop15h 37m
Frontier
Deal found 5/7![Frontier logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:43 am
SAN
- TYS
2 stops30h 54m
Multiple Airlines
Sun 8/97:00 am
TYS
- SAN
1 stop29h 05m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:25 am
SAN
- TYS
1 stop10h 11m
Multiple Airlines
Sun 8/27:00 am
TYS
- SAN
1 stop29h 05m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$324
Best flights from San Diego to KnoxvilleDiscover carefully curated flight deals from San Diego to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
Discover carefully curated flight deals from San Diego to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:45 pm
SAN
- TYS
1 stop9h 19m
American Airlines
Tue 8/116:00 am
TYS
- SAN
1 stop7h 19m
American Airlines
Deal found 5/6![American Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:40 am
SAN
- TYS
1 stop12h 50m
Southwest
Wed 8/53:00 pm
TYS
- SAN
1 stop8h 30m
Southwest
Deal found 5/8![Southwest logo]()
$402
This Alaska Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:55 am
SAN
- TYS
2 stops13h 23m
Alaska Airlines
Sat 9/193:05 pm
TYS
- SAN
1 stop10h 31m
Alaska Airlines
Deal found 5/11![Alaska Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:42 pm
SAN
- TYS
2 stops10h 01m
United Airlines
Tue 8/115:45 am
TYS
- SAN
1 stop8h 32m
United Airlines
Deal found 5/6![United Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/71:58 pm
SAN
- TYS
1 stop6h 54m
Delta
Mon 8/104:38 pm
TYS
- SAN
1 stop9h 22m
Delta
Deal found 5/6![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/39:00 am
SAN
- TYS
2 stops9h 10m
Southwest
Sat 8/86:50 am
TYS
- SAN
1 stop6h 00m
Southwest
Deal found 5/7![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:40 pm
SAN
- TYS
1 stop8h 08m
United Airlines
Sat 9/196:30 am
TYS
- SAN
2 stops13h 56m
United Airlines
Deal found 5/11![United Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:40 pm
SAN
- TYS
1 stop8h 03m
United Airlines
Sat 6/66:00 am
TYS
- SAN
1 stop8h 21m
United Airlines
Deal found 5/6![United Airlines logo]()
$447
This Alaska Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:00 am
SAN
- TYS
1 stop8h 13m
Alaska Airlines
Tue 6/231:54 pm
TYS
- SAN
1 stop9h 35m
Alaska Airlines
Deal found 5/7![Alaska Airlines logo]()
$497
Last-minute flights from San Diego to KnoxvilleDiscover last-minute flight deals from San Diego to Knoxville. Data last updated May 11, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Knoxville. Data last updated May 11, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/259:37 am
SAN
- TYS
1 stop6h 47m
Frontier
Fri 5/298:19 pm
TYS
- SAN
1 stop6h 31m
Frontier
Deal found 5/9![Frontier logo]()
$270
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:08 pm
SAN
- TYS
1 stop7h 01m
United Airlines
Wed 6/36:00 am
TYS
- SAN
1 stop8h 21m
United Airlines
Deal found 5/6![United Airlines logo]()
$347
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/61:55 pm
SAN
- TYS
1 stop7h 00m
American Airlines
Sat 6/138:11 pm
TYS
- SAN
1 stop6h 48m
American Airlines
Deal found 5/7![American Airlines logo]()
$337
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:37 am
SAN
- TYS
1 stop6h 56m
Frontier
Wed 6/108:32 pm
TYS
- SAN
1 stop15h 37m
Frontier
Deal found 5/7![Frontier logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:43 am
SAN
- TYS
2 stops30h 54m
Multiple Airlines
Sun 8/97:00 am
TYS
- SAN
1 stop29h 05m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:28 pm
SAN
- TYS
1 stop27h 09m
Multiple Airlines
Sat 6/135:56 pm
TYS
- SAN
2 stops17h 52m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$327
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:25 am
SAN
- TYS
1 stop10h 12m
Frontier
Wed 6/178:32 pm
TYS
- SAN
1 stop15h 37m
Frontier
Deal found 5/11![Frontier logo]()
$220
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:25 am
SAN
- TYS
1 stop10h 12m
Frontier
Mon 6/228:32 pm
TYS
- SAN
1 stop15h 37m
Frontier
Deal found 5/11![Frontier logo]()
$280
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:25 am
SAN
- TYS
1 stop10h 12m
Frontier
Fri 6/268:32 pm
TYS
- SAN
1 stop15h 10m
Frontier
Deal found 5/7![Frontier logo]()
$260
This CheapOair deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2610:04 am
SAN
- TYS
1 stop6h 33m
Frontier
Mon 6/298:32 pm
TYS
- SAN
1 stop15h 37m
Frontier
Deal found 5/10![Frontier logo]()
$345
One-way flights from San Diego to KnoxvilleSearch for one-way flight options from San Diego to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
Search for one-way flight options from San Diego to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
This Priceline deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:25 am
SAN
- TYS
1 stop10h 12m
Frontier
Deal found 5/10![Frontier logo]()
$111
This Priceline deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:37 am
SAN
- TYS
1 stop7h 00m
Frontier
Deal found 5/10![Frontier logo]()
$125
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:25 am
SAN
- TYS
1 stop10h 12m
Frontier
Deal found 5/10![Frontier logo]()
$131
This Mytrip deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:28 pm
SAN
- TYS
1 stop27h 09m
Frontier
Deal found 5/10![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:53 pm
SAN
- TYS
2 stops35h 10m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$137
This Priceline deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:25 am
SAN
- TYS
1 stop9h 59m
Frontier
Deal found 5/7![Frontier logo]()
$141
This Priceline deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:04 am
SAN
- TYS
1 stop6h 32m
Frontier
Deal found 5/11![Frontier logo]()
$145
This Priceline deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:25 am
SAN
- TYS
1 stop10h 12m
Frontier
Deal found 5/6![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/249:43 am
SAN
- TYS
2 stops47h 16m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:25 am
SAN
- TYS
1 stop28h 27m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$167
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:50 pm
SAN
- TYS
1 stop7h 11m
Delta
Deal found 5/7![Delta logo]()
$169
Find flight deals from San Diego to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $220 (CheapOair) |
One-way from | $111 (Priceline) |
Popular in | November |
Cheapest in | September |
Average price | $390 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from San Diego to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 8/8
10:45 pm-11:04 am
1 stop9h 19m
Knoxville McGhee Tyson
Tue 8/11
6:00 am-10:19 am
1 stop7h 19m
$357
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Fri 7/31
6:40 am-10:30 pm
1 stop12h 50m
Knoxville McGhee Tyson
Wed 8/5
3:00 pm-8:30 pm
1 stop8h 30m
$402
Quickest round-trip
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Mon 8/3
9:00 am-9:10 pm
2 stops9h 10m
Knoxville McGhee Tyson
Sat 8/8
6:50 am-9:50 am
1 stop6h 00m
$407
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 9/1
6:55 am-11:18 pm
2 stops13h 23m
Knoxville McGhee Tyson
Sat 9/19
3:05 pm-10:36 pm
1 stop10h 31m
$442
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Sat 8/8
8:42 pm-9:43 am
2 stops10h 01m
Knoxville McGhee Tyson
Tue 8/11
5:45 am-11:17 am
1 stop8h 32m
$442
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 9/1
10:40 pm-9:48 am
1 stop8h 08m
Knoxville McGhee Tyson
Sat 9/19
6:30 am-5:26 pm
2 stops13h 56m
$442
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 6/2
10:40 pm-9:43 am
1 stop8h 03m
Knoxville McGhee Tyson
Sat 6/6
6:00 am-11:21 am
1 stop8h 21m
$447
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Fri 8/7
1:58 pm-11:52 pm
1 stop6h 54m
Knoxville McGhee Tyson
Mon 8/10
4:38 pm-11:00 pm
1 stop9h 22m
$467
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Tue 6/16
7:00 am-6:13 pm
1 stop8h 13m
Knoxville McGhee Tyson
Tue 6/23
1:54 pm-8:29 pm
1 stop9h 35m
$497
Cheapest one-way
San DiegoKnoxville
SAN - TYS
SANTYS
San Diego
Mon 6/22
6:25 am-7:37 pm
1 stop10h 12m
$131
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from San Diego to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Knoxville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Diego with our price prediction graph.
SAN-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Knoxville
Prices
Delays
How far ahead should I book a flight from San Diego to Knoxville?
Booking 32 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Knoxville?
Currently, September is the cheapest month in which you can book a flight from San Diego to Knoxville (average of $306). Flying from San Diego to Knoxville in November is currently the most expensive (average of $542). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Knoxville?
How often are flights from San Diego to Knoxville delayed?
About 0% of weekly flights between San Diego and Knoxville have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for San Diego to Knoxville flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 11, 2026.
See what other customers who have flown with Alaska Airlines,Delta, andUnited Airlines from San Diego to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Entertainment
7.0
Crew
8.5
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Overall
7.9
Entertainment
7.0
Crew
8.5
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Overall
7.9
Entertainment
7.0
Crew
8.5
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Overall
7.9
Entertainment
7.0
Crew
8.5
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Overall
7.9
Entertainment
7.0
Crew
8.5
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Overall
7.9
Entertainment
7.0
Crew
8.5
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentFranzi,Mar 2026
SFO - PDX
Related info for your journey
Find useful and relevant information for your journey from San Diego to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 11, 2026.
San Diego and Knoxville flights
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Top 5 airlines flying from San Diego to Knoxville
Discover the top 5 airlines that operate flights from San Diego to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$65 | Average$270 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$276 | Average$465 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$276 | Average$433 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$439 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$496 | Average$798 | FlexibilityNo cancel fee | On-time75% |