$180+ Cheap flights from Santa Ana, CA to Knoxville (SNA - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — TYS
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to Knoxville
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Cheapest flights from Santa Ana to KnoxvilleExplore the most affordable flight options available from Santa Ana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Santa Ana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:30 am -
1 stop10h 09m
Mon 10/269:42 pm -
1 stop20h 21m
Deal found 9/4![Multiple Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:26 pm -
1 stop6h 52m
Sat 10/246:00 am -
1 stop8h 00m
Deal found 9/8![American Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:29 am -
1 stop7h 45m
Wed 10/2810:45 am -
2 stops9h 48m
Deal found 9/8![United Airlines logo]()
$368
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:35 am -
2 stops8h 10m
Mon 12/77:05 am -
2 stops9h 55m
Deal found 9/8![Southwest logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:08 pm -
2 stops28h 31m
Mon 10/199:59 pm -
1 stop20h 04m
Deal found 9/4![Multiple Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:43 pm -
1 stop7h 18m
Sun 10/46:00 am -
1 stop29h 45m
Deal found 9/4![Multiple Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:00 am -
1 stop8h 45m
Mon 12/144:15 pm -
1 stop8h 30m
Deal found 9/7![Southwest logo]()
$386
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:45 am -
2 stops9h 00m
Sat 11/145:20 pm -
1 stop6h 40m
Deal found 9/7![Southwest logo]()
$391
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1312:10 pm -
1 stop8h 22m
Wed 12/162:55 pm -
1 stop7h 15m
Deal found 9/9![American Airlines logo]()
$415
Best flights from Santa Ana to KnoxvilleDiscover carefully curated flight deals from Santa Ana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Santa Ana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:45 am -
2 stops8h 45m
Tue 11/174:15 pm -
1 stop8h 30m
Deal found 9/8![Southwest logo]()
$420
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:05 pm -
1 stop6h 09m
Wed 10/77:15 am -
1 stop6h 47m
Deal found 9/4![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:15 am -
2 stops12h 07m
Sat 10/242:38 pm -
1 stop7h 00m
Deal found 9/5![Delta logo]()
$543
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:45 am -
2 stops9h 00m
Mon 11/25:25 pm -
1 stop7h 25m
Deal found 9/5![Southwest logo]()
$458
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/307:50 pm -
2 stops11h 00m
Wed 2/34:25 pm -
1 stop8h 49m
Deal found 9/8![United Airlines logo]()
$468
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/138:35 am -
2 stops9h 05m
Sat 2/206:35 am -
2 stops14h 40m
Deal found 9/6![Southwest logo]()
$469
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:09 pm -
1 stop6h 23m
Mon 11/25:05 pm -
1 stop7h 14m
Deal found 9/5![United Airlines logo]()
$524
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:08 pm -
1 stop6h 49m
Sun 11/229:00 am -
1 stop8h 59m
Deal found 9/8![United Airlines logo]()
$525
Last-minute flights from Santa Ana to KnoxvilleDiscover last-minute flight deals from Santa Ana to Knoxville. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Knoxville. Data last updated September 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:43 pm -
1 stop7h 18m
Sun 10/46:00 am -
1 stop29h 45m
Deal found 9/4![Multiple Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:43 pm -
1 stop7h 18m
Mon 10/59:54 pm -
1 stop20h 09m
Deal found 9/8![Multiple Airlines logo]()
$424
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:08 pm -
2 stops28h 31m
Mon 10/199:59 pm -
1 stop20h 04m
Deal found 9/4![Multiple Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:26 pm -
1 stop6h 52m
Sat 10/246:00 am -
1 stop8h 00m
Deal found 9/8![American Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:29 am -
1 stop7h 45m
Wed 10/2810:45 am -
2 stops9h 48m
Deal found 9/8![United Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:30 am -
1 stop10h 09m
Mon 10/269:42 pm -
1 stop20h 21m
Deal found 9/4![Multiple Airlines logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:30 am -
1 stop10h 09m
Sun 10/259:29 pm -
2 stops26h 59m
Deal found 9/5![Multiple Airlines logo]()
$443
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:38 am -
2 stops30h 12m
Sun 10/256:30 am -
1 stop7h 22m
Deal found 9/9![Multiple Airlines logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:34 pm -
2 stops18h 09m
Mon 10/269:42 pm -
1 stop20h 21m
Deal found 9/8![Multiple Airlines logo]()
$422
One-way flights from Santa Ana to KnoxvilleSearch for one-way flight options from Santa Ana to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Santa Ana to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:59 pm -
1 stop15h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Allegiant Air logo]()
$180
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:40 pm -
1 stop6h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:43 pm -
1 stop7h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:30 am -
1 stop10h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:39 pm -
1 stop21h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:54 pm -
3 stops58h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:01 am -
2 stops28h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Allegiant Air logo]()
$228
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/177:45 am -
1 stop7h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$234
Find flight deals from Santa Ana to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $358 (Kiwi.com) |
One-way from | $180 (Kiwi.com) |
Popular in | June |
Cheapest in | September |
Average price | $412 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Santa Ana to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Fri 10/2
10:45 am-8:13 am
3 stops42h 28m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$199
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Sun 12/6
5:36 pm-1:07 pm
2 stops40h 31m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$214
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Fri 10/2
10:01 am-5:53 pm
2 stops28h 52m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$228
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Sun 1/17
7:45 am-6:44 pm
1 stop7h 59m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$234
Quickest round-trip
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Sat 10/17
10:37 am-8:49 pm
1 stop7h 12m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$270
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Wed 9/30
6:36 pm-10:37 am
2 stops13h 01m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$275
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Sat 12/26
6:45 am-5:10 pm
1 stop7h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$294
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Tue 12/22
11:10 am-10:35 pm
2 stops8h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$316
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Mon 12/21
10:25 am-10:35 pm
2 stops9h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$316
Santa AnaKnoxville
SNA Santa Ana J. Wayne/Orange Cnty - TYS Knoxville McGhee Tyson
SNATYS
Santa Ana J. Wayne/Orange Cnty
Sun 11/15
8:45 am-8:30 pm
2 stops8h 45m
Knoxville McGhee Tyson
Tue 11/17
4:15 pm-9:45 pm
1 stop8h 30m
$420
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Santa Ana with our price prediction graph.
SNA-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to Knoxville
How far ahead should I book a flight from Santa Ana, California to Knoxville?
Booking 57 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santa Ana, California to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Santa Ana, California to Knoxville?
Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Knoxville (average of $412). Flying from Santa Ana, California to Knoxville in June is currently the most expensive (average of $727). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to Knoxville?
Airfare is below average for this route at the moment.
Santa Ana, California to Knoxville flights typically cost between $388 and $574 in October.The cheapest round-trip price found within the last 5 days was $358 on Multiple Airlines (Oct 22-Oct 26).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 9, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Santa Ana to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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Find flights from Santa Ana to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Santa Ana and Knoxville flights
Browse other Santa Ana and Knoxville flight options. Last updated on September 9, 2026.
Other flights from Santa Ana
Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Santa Ana to Knoxville
Discover the top 4 airlines that operate flights from Santa Ana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$229 | Average$428 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$288 | Average$566 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$536 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$378 | Average$556 | FlexibilityNo cancel fee | On-time63% |