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$370+ Cheap flights from Des Moines (DSM) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROM
dic. 31 — ene. 71
mié. 12/31
mié. 1/7
1 adult, Economy
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Find flight deals from Des Moines to Rome

Cheapest flights from Des Moines to Rome
Explore the most affordable flight options available from Des Moines to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 1, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/811:35 amDSM - FCO
1 stop13h 10mLufthansa
lun. 12/157:05 amFCO - DSM
2 stops21h 32mLufthansa
Deal found 12/1$462
This Orbitz deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/88:50 amDSM - FCO
2 stops22h 05mIberia
lun. 12/158:20 pmFCO - DSM
2 stops33h 09mIberia
Deal found 12/1$488
This United Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/911:35 amDSM - FCO
1 stop13h 10mUnited Airlines
jue. 12/189:45 amFCO - DSM
1 stop18h 55mUnited Airlines
Deal found 12/1$564
This oojo deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:52 pmDSM - FCO
2 stops34h 28mBritish Airways
mar. 1/138:25 pmFCO - DSM
2 stops31h 39mBritish Airways
Deal found 11/28$589
This FlightHub deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/96:50 pmDSM - FCO
1 stop29h 55mLufthansa
jue. 12/189:45 amFCO - DSM
1 stop15h 20mLufthansa
Deal found 12/1$708
This KLM deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/292:18 pmDSM - FCO
1 stop34h 37mKLM
mar. 1/136:10 amFCO - DSM
2 stops16h 31mKLM
Deal found 11/28$777
This United Airlines deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/306:46 pmDSM - FCO
2 stops30h 44mUnited Airlines
mar. 1/61:30 pmFCO - DSM
2 stops39h 20mUnited Airlines
Deal found 11/30$966
This Finnair deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/305:07 amDSM - FCO
1 stop22h 38mMultiple Airlines
mar. 1/611:00 amFCO - DSM
2 stops19h 08mMultiple Airlines
Deal found 11/30$1,078
This Ovago deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/11:53 pmDSM - FCO
2 stops37h 47mAer Lingus
dom. 12/711:20 amFCO - DSM
2 stops18h 09mAer Lingus
Deal found 11/29$1,107

Cheap flight deals from Des Moines to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated diciembre 1, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$442
(Ticket)

One-way from

$370
(American Airlines)

Popular in

June

Cheapest in

November

Average price

$773
Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.
Search Deals
From Des Moines to Rome (ROM)
Search Deals
One-way flight from Des Moines to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($296 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($56 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 1, 2025.
Use the filters below to find and compare flights from Des Moines to Rome that are best for you.

Fly from

Des Moines

Fly to

Rome

Route

Depart

Return

Price

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

lun. 3/23

11:17 am-10:35 am

1 stop17h 18m

Rome Fiumicino

mié. 4/1

1:10 pm-10:19 pm

1 stop16h 09m

$456

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

mié. 1/14

12:04 pm-11:55 am

2 stops16h 51m

Rome Fiumicino

mié. 1/21

12:40 pm-10:29 pm

1 stop16h 49m

$466

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

jue. 1/15

12:04 pm-11:55 am

2 stops16h 51m

Rome Fiumicino

jue. 1/22

12:40 pm-4:29 pm

1 stop34h 49m

$467

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

mar. 1/13

11:42 am-12:20 pm

2 stops17h 38m

Rome Fiumicino

mar. 1/20

8:25 pm-9:04 pm

2 stops31h 39m

$473

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

mar. 1/13

12:04 pm-3:15 pm

2 stops20h 11m

Rome Fiumicino

mar. 1/20

12:40 pm-10:29 pm

1 stop16h 49m

$475

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

mié. 1/14

11:26 am-3:15 pm

2 stops20h 49m

Rome Fiumicino

mié. 1/21

12:40 pm-10:29 pm

1 stop16h 49m

$475

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

mar. 1/13

11:42 am-12:20 pm

2 stops17h 38m

$370

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

mar. 1/13

11:26 am-10:30 am

1 stop16h 04m

$396

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

mar. 1/13

8:00 am-12:40 pm

3 stops21h 40m

$439

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

mié. 4/15

1:34 pm-12:20 pm

1 stop15h 46m

$448

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/29

Showing 1-10 of 13 results
1
2

Compare providers for flights from Des Moines to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Rome in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Rome flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Rome flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Rome flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Rome

What is the cheapest month to book a flight from Des Moines to Rome?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Rome (average of $590). Flying from Des Moines to Rome in July is currently the most expensive (average of $1,065). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Rome?

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated diciembre 1, 2025.
See what other customers who have flown with Delta, KLM, and United Airlines from Des Moines to Rome have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,424 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,059 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,039 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,548 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Rome?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Rome from Des Moines. Booking flights from Des Moines (DSM) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 3 different airlines.

  • How long is the flight from Des Moines to Rome?

    A quick flight from Des Moines to Rome can take about 16h 51m. KLM provides one of the quickest options available for as low as $466. The distance from Des Moines to Rome is about 5054 mi.

  • What are the cheapest airlines flying from Des Moines to Rome round-trip?

    Currently priced at $641, Delta will fly you from Des Moines to Rome and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and KLM - these airlines can fly you to your destination from $655 and $680, respectively. These flights start at 35% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Rome one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $370. Users have also found prices from $396 and $439 on KLM and Air Canada, respectively.

  • Can I find deals for flights from Des Moines to Rome that include hotel bookings?

    Yes. In addition to deals on Des Moines to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Rome.

  • Can I find deals for business class flights from Des Moines to Rome?

    Yes. Cheapflights offers flight deals from Des Moines to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Rome?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Rome (average of $590). Flying from Des Moines to Rome in July is currently the most expensive (average of $1,065). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Top 3 airlines flying from Des Moines to Rome

Discover the top 3 airlines that operate flights from Des Moines to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$641Average$1,064FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$655Average$1,196FlexibilityNo cancel feeOn-time69%
KLMCheapest$680Average$1,091FlexibilityNo cancel feeOn-time75%

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