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$373+ Cheap flights from Des Moines (DSM) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROM
dez 24 — dez 311
qua 12/24
qua 12/31
1 adult, Economy
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Find flight deals from Des Moines to Rome

Cheapest flights from Des Moines to Rome
Explore the most affordable flight options available from Des Moines to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on novembro 24, 2025.

This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/306:46 pmDSM - FCO
2 stops30h 44mUnited Airlines
qua 1/1411:15 amFCO - DSM
2 stops41h 35mUnited Airlines
Deal found 11/24$488
This KLM deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/305:35 amDSM - FCO
1 stop19h 20mKLM
qua 1/146:10 amFCO - DSM
2 stops21h 44mKLM
Deal found 11/24$506
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/306:46 pmDSM - FCO
2 stops30h 44mUnited Airlines
seg 1/127:05 amFCO - DSM
2 stops21h 45mUnited Airlines
Deal found 11/24$507
This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/306:15 amDSM - FCO
1 stop18h 40mDelta
qua 1/1412:40 pmFCO - DSM
1 stop28h 58mDelta
Deal found 11/24$611
This Booking.com deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/296:46 pmDSM - FCO
2 stops33h 09mMultiple Airlines
seg 1/127:05 pmFCO - DSM
2 stops33h 45mMultiple Airlines
Deal found 11/24$613
This FlightHub deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/296:46 pmDSM - FCO
2 stops33h 09mMultiple Airlines
ter 1/137:00 amFCO - DSM
2 stops21h 50mMultiple Airlines
Deal found 11/22$617
This Air Canada deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/308:00 amDSM - FCO
2 stops19h 55mMultiple Airlines
qua 1/147:05 amFCO - DSM
3 stops21h 45mMultiple Airlines
Deal found 11/24$714
This KLM deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 12/296:30 pmDSM - FCO
1 stop30h 25mKLM
ter 1/136:10 amFCO - DSM
2 stops16h 31mKLM
Deal found 11/22$801
This Air Canada deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/308:00 amDSM - FCO
2 stops19h 55mMultiple Airlines
seg 1/127:05 amFCO - DSM
3 stops21h 45mMultiple Airlines
Deal found 11/24$815
This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/3011:23 amDSM - FCO
1 stop13h 32mDelta
seg 1/1212:40 pmFCO - DSM
1 stop28h 58mDelta
Deal found 11/24$841
This Gotogate deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 12/258:00 amDSM - FCO
2 stops19h 55mMultiple Airlines
qui 1/89:40 amFCO - DSM
2 stops43h 10mMultiple Airlines
Deal found 11/24$904

Cheap flight deals from Des Moines to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated novembro 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$473
(Bravofly)

One-way from

$373
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$635
Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.
Search Deals
From Des Moines to Rome (ROM)
Search Deals
One-way flight from Des Moines to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($296 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($56 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated novembro 24, 2025.
Use the filters below to find and compare flights from Des Moines to Rome that are best for you.

Fly from

Des Moines

Fly to

Rome

Route

Depart

Return

Price

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

qua 1/7

6:48 pm-5:50 pm

2 stops40h 02m

Rome Fiumicino

qua 1/14

12:20 pm-9:50 pm

2 stops16h 30m

$473

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

sáb 1/17

12:25 pm-10:30 am

2 stops15h 05m

Rome Fiumicino

dom 1/25

12:40 pm-10:29 pm

1 stop16h 49m

$485

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

sex 2/6

3:35 pm-8:30 am

2 stops33h 55m

Rome Fiumicino

seg 2/16

11:15 am-2:27 pm

2 stops34h 12m

$488

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

sáb 1/17

6:48 pm-9:25 am

2 stops31h 37m

Rome Fiumicino

dom 1/25

12:45 pm-8:34 pm

2 stops38h 49m

$490

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

seg 1/12

3:04 pm-9:25 am

2 stops35h 21m

Rome Fiumicino

ter 1/20

1:10 pm-5:47 pm

2 stops35h 37m

$490

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

qua 2/11

8:00 am-11:00 pm

2 stops32h 00m

Rome Fiumicino

qua 2/18

11:15 am-2:27 pm

2 stops34h 12m

$491

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

sex 1/30

8:00 am-7:55 am

2 stops16h 55m

Rome Fiumicino

ter 2/3

1:10 pm-9:50 pm

2 stops39h 40m

$494

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

sex 12/12

9:00 am-8:30 am

3 stops40h 30m

$373

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

sáb 11/29

10:55 am-2:30 pm

2 stops44h 35m

$382

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

qua 1/7

6:48 pm-8:00 pm

2 stops18h 12m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 14 results
1
2

Compare providers for flights from Des Moines to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Rome in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Rome flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Rome flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Rome flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Rome

What is the cheapest month to book a flight from Des Moines to Rome?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Rome (average of $590). Flying from Des Moines to Rome in July is currently the most expensive (average of $1,065). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Rome?

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated novembro 24, 2025.
See what other customers who have flown with Delta, KLM, and United Airlines from Des Moines to Rome have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,993 reviews

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
7,993 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,419 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,039 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,043 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,535 reviews
Delta
7.9
Good
7,993 reviews

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Rome?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Rome from Des Moines. Booking flights from Des Moines (DSM) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 3 different airlines.

  • How long is the flight from Des Moines to Rome?

    A quick flight from Des Moines to Rome can take about 33h 55m. Lufthansa provides one of the quickest options available for as low as $488. The distance from Des Moines to Rome is about 5054 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Rome round-trip?

    Currently priced at $641, Delta will fly you from Des Moines to Rome and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and KLM - these airlines can fly you to your destination from $655 and $680, respectively. These flights start at 35% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to Rome that include hotel bookings?

    Yes. In addition to deals on Des Moines to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Rome.

  • Can I find deals for business class flights from Des Moines to Rome?

    Yes. Cheapflights offers flight deals from Des Moines to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Rome?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Rome (average of $590). Flying from Des Moines to Rome in July is currently the most expensive (average of $1,065). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Top 3 airlines flying from Des Moines to Rome

Discover the top 3 airlines that operate flights from Des Moines to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated novembro 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$641Average$1,064FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$655Average$1,196FlexibilityNo cancel feeOn-time69%
KLMCheapest$680Average$1,091FlexibilityNo cancel feeOn-time75%

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