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$549+ Cheap flights from Des Moines (DSM) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROM
Mar 21 — Mar 281
Sat 3/21
Sat 3/28
1 adult, Economy
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Cheap flight deals from Des Moines to Rome

Cheapest flights from Des Moines to Rome
Explore the most affordable flight options available from Des Moines to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 19, 2026.

This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:47 pm
DSM
-
FCO
2 stops19h 58m
Delta
Wed 3/2512:45 pm
FCO
-
DSM
2 stops28h 03m
Delta
Deal found 2/16$614
This FlightHub deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:15 pm
DSM
-
FCO
2 stops37h 50m
Scandinavian Airlines
Fri 8/2111:55 am
FCO
-
DSM
2 stops41h 31m
Scandinavian Airlines
Deal found 2/18$626
This Justfly.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:15 pm
DSM
-
FCO
2 stops37h 50m
Scandinavian Airlines
Wed 9/911:55 am
FCO
-
DSM
2 stops41h 31m
Scandinavian Airlines
Deal found 2/18$656
This KAYAK deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:15 pm
DSM
-
FCO
2 stops35h 25m
Scandinavian Airlines
Thu 9/1011:55 am
FCO
-
DSM
2 stops41h 31m
Scandinavian Airlines
Deal found 2/18$660
This Cheapflightsfares deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:45 pm
DSM
-
FCO
2 stops20h 15m
Lufthansa
Tue 8/251:20 pm
FCO
-
DSM
2 stops16h 31m
Lufthansa
Deal found 2/16$677
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:15 am
DSM
-
FCO
1 stop18h 40m
United Airlines
Tue 8/2511:30 am
FCO
-
DSM
2 stops35h 44m
United Airlines
Deal found 2/16$687
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:00 am
DSM
-
FCO
1 stop17h 45m
United Airlines
Tue 3/2411:00 am
FCO
-
DSM
2 stops32h 23m
United Airlines
Deal found 2/18$688
This KAYAK deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3011:04 am
DSM
-
FCO
2 stops41h 01m
Scandinavian Airlines
Thu 9/1011:55 am
FCO
-
DSM
2 stops41h 31m
Scandinavian Airlines
Deal found 2/18$690
This Air Canada deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:00 am
DSM
-
FCO
2 stops20h 45m
Air Canada
Tue 8/2511:30 am
FCO
-
DSM
2 stops35h 44m
Air Canada
Deal found 2/18$691
This Air Canada deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
DSM
-
FCO
2 stops20h 15m
Air Canada
Fri 8/2112:25 pm
FCO
-
DSM
2 stops32h 46m
Air Canada
Deal found 2/18$696
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:15 am
DSM
-
FCO
2 stops18h 20m
United Airlines
Wed 8/1910:20 am
FCO
-
DSM
2 stops19h 31m
United Airlines
Deal found 2/18$697
This KLM deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:04 am
DSM
-
FCO
1 stop13h 31m
KLM
Wed 8/191:10 pm
FCO
-
DSM
1 stop35h 32m
KLM
Deal found 2/18$699

Find flight deals from Des Moines to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 19, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$614
(Delta)

One-way from

$549
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$724
Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.
Search Deals
From Des Moines to Rome (ROM)
Search Deals
One-way flight from Des Moines to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($234 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
Use the filters below to find and compare flights from Des Moines to Rome that are best for you.

Fly from

Des Moines

Fly to

Rome

Route

Depart

Return

Price

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 3/18

5:47 pm-7:45 pm

2 stops19h 58m

Rome Fiumicino

Wed 3/25

12:45 pm-10:48 am

2 stops28h 03m

$614

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 3/18

2:04 pm-10:05 am

2 stops38h 01m

Rome Fiumicino

Tue 3/24

11:00 am-10:30 am

2 stops29h 30m

$706

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 3/10

8:00 am-7:45 am

1 stop17h 45m

Rome Fiumicino

Tue 3/17

9:45 am-9:40 pm

1 stop17h 55m

$707

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 3/10

7:30 am-6:05 am

1 stop16h 35m

Rome Fiumicino

Wed 3/18

8:20 am-7:27 pm

1 stop17h 07m

$707

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 3/9

7:30 am-6:05 am

1 stop16h 35m

Rome Fiumicino

Wed 3/18

8:20 am-8:45 pm

2 stops18h 25m

$712

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 3/17

2:04 pm-7:45 am

1 stop11h 41m

Rome Fiumicino

Tue 3/24

11:00 am-10:30 am

2 stops29h 30m

$712

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 3/9

8:00 am-8:30 am

2 stops18h 30m

Rome Fiumicino

Tue 3/17

10:30 am-9:40 pm

2 stops17h 10m

$712

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 4/7

1:10 pm-6:15 pm

2 stops22h 05m

Rome Fiumicino

Mon 4/13

7:05 pm-9:27 pm

2 stops33h 22m

$804

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Fri 5/15

2:20 pm-12:15 am

3 stops50h 55m

$549

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Fri 5/15

5:17 pm-10:20 am

2 stops58h 03m

$608

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Showing 1-10 of 11 results
1
2

Compare providers for flights from Des Moines to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Rome in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Rome flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Rome flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Rome flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Rome

What is the cheapest month to book a flight from Des Moines to Rome?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Rome (average of $464). Flying from Des Moines to Rome in May is currently the most expensive (average of $1,436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated February 19, 2026.
See what other customers who have flown with Delta, KLM, and United Airlines from Des Moines to Rome have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,212 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,212 reviews
Delta
7.9
Good
8,212 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,459 reviews
Delta
7.9
Good
8,212 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,322 reviews
Delta
7.9
Good
8,212 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,313 reviews
Delta
7.9
Good
8,212 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,752 reviews
Delta
7.9
Good
8,212 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Rome?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Rome from Des Moines. Booking flights from Des Moines (DSM) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 3 different airlines.

  • How long is the flight from Des Moines to Rome?

    A quick flight from Des Moines to Rome can take about 19h 58m. Delta provides one of the quickest options available for as low as $614. The distance from Des Moines to Rome is about 5054 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Rome round-trip?

    Currently priced at $457, KLM will fly you from Des Moines to Rome and back. In addition to KLM, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and Delta - these airlines can fly you to your destination from $491 and $641, respectively. These flights start at 52% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to Rome that include hotel bookings?

    Yes. In addition to deals on Des Moines to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Rome.

  • Can I find deals for business class flights from Des Moines to Rome?

    Yes. Cheapflights offers flight deals from Des Moines to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Rome?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Rome (average of $464). Flying from Des Moines to Rome in May is currently the most expensive (average of $1,436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Top 3 airlines flying from Des Moines to Rome

Discover the top 3 airlines that operate flights from Des Moines to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
KLMCheapest$457Average$1,013FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$491Average$718FlexibilityNo cancel feeOn-time69%
DeltaCheapest$641Average$1,063FlexibilityNo cancel feeOn-timeN/A

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