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$422+ Cheap flights from Des Moines (DSM) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ROM
Jul 6 — Jul 131
Mon 7/6
Mon 7/13
1 adult, Economy
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Cheap flight deals from Des Moines to Rome

Cheapest flights from Des Moines to Rome
Explore the most affordable flight options available from Des Moines to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 6, 2026.

This FlightHub deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:45 pm
DSM
-
FCO
2 stops21h 15m
Lufthansa
Mon 3/87:05 pm
FCO
-
DSM
2 stops34h 56m
Lufthansa
Deal found 6/4$797
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:35 pm
DSM
-
FCO
1 stop15h 45m
United Airlines
Thu 8/2011:30 am
FCO
-
DSM
2 stops33h 46m
United Airlines
Deal found 6/3$804
This FlightHub deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:00 am
DSM
-
FCO
2 stops20h 45m
Air Canada
Thu 8/2011:30 am
FCO
-
DSM
2 stops40h 53m
Air Canada
Deal found 6/5$808
This Air Canada deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:30 am
DSM
-
FCO
2 stops38h 25m
Air Canada
Wed 12/161:15 pm
FCO
-
DSM
2 stops39h 02m
Air Canada
Deal found 6/2$809
This Air Canada deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:45 pm
DSM
-
FCO
2 stops55h 10m
Air Canada
Wed 12/161:15 pm
FCO
-
DSM
2 stops31h 56m
Air Canada
Deal found 6/2$814
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:00 am
DSM
-
FCO
1 stop19h 45m
United Airlines
Thu 12/179:55 am
FCO
-
DSM
2 stops21h 45m
United Airlines
Deal found 6/2$819
This KAYAK deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:45 pm
DSM
-
FCO
1 stop15h 10m
Lufthansa
Tue 12/159:45 am
FCO
-
DSM
1 stop14h 48m
Lufthansa
Deal found 6/2$820
This Air Canada deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:32 am
DSM
-
FCO
3 stops17h 13m
Multiple Airlines
Thu 8/202:20 pm
FCO
-
DSM
2 stops27h 06m
Multiple Airlines
Deal found 6/4$821
This KLM deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:34 pm
DSM
-
FCO
1 stop13h 16m
KLM
Thu 8/209:00 am
FCO
-
DSM
1 stop15h 11m
KLM
Deal found 6/1$824
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:30 pm
DSM
-
FCO
2 stops19h 15m
Delta
Wed 12/1612:25 pm
FCO
-
DSM
1 stop13h 47m
Delta
Deal found 6/2$825
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/241:05 pm
DSM
-
FCO
1 stop11h 40m
United Airlines
Mon 12/1412:20 pm
FCO
-
DSM
2 stops38h 05m
United Airlines
Deal found 6/2$831

Find flight deals from Des Moines to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 6, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$774
(Air Canada)

One-way from

$422
(oojo)

Popular in

June

Cheapest in

November

Average price

$1,333
Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.
Search Deals
From Des Moines to Rome (ROM)
Search Deals
One-way flight from Des Moines to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($194 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
Use the filters below to find and compare flights from Des Moines to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

6:00 am-1:15 pm

2 stops24h 15m

Rome Fiumicino

Thu 8/20

11:30 am-2:16 pm

2 stops33h 46m

$804

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

11:28 am-7:35 am

1 stop13h 07m

Rome Fiumicino

Thu 8/20

9:45 am-10:37 pm

1 stop19h 52m

$824

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sun 10/4

5:44 am-7:35 am

1 stop18h 51m

Rome Fiumicino

Fri 10/16

9:00 am-8:52 pm

1 stop18h 52m

$924

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 9/7

6:00 am-11:00 am

1 stop22h 00m

Rome Fiumicino

Thu 9/17

9:00 am-5:19 pm

1 stop15h 19m

$925
Quickest round-trip

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 9/8

5:25 pm-2:25 pm

2 stops14h 00m

Rome Fiumicino

Fri 9/18

6:30 am-2:01 pm

2 stops14h 31m

$928

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 9/9

5:45 am-12:20 pm

1 stop23h 35m

Rome Fiumicino

Fri 9/18

6:50 am-9:28 pm

2 stops21h 38m

$960

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 10/6

5:45 am-7:35 am

1 stop18h 50m

Rome Fiumicino

Wed 10/28

10:25 am-10:29 pm

1 stop18h 04m

$960

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 9/9

11:33 am-12:20 pm

1 stop17h 47m

Rome Fiumicino

Tue 9/15

9:45 am-5:28 pm

1 stop14h 43m

$961

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 9/9

5:45 am-12:20 pm

1 stop23h 35m

Rome Fiumicino

Thu 9/17

9:45 am-9:28 pm

1 stop18h 43m

$961

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 10/6

8:00 am-10:55 am

3 stops19h 55m

Rome Fiumicino

Wed 10/28

7:05 pm-12:40 am

2 stops35h 35m

$975

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/3

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Rome in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Rome flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Des Moines-Rome flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Des Moines-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Rome flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Rome

What is the cheapest month to book a flight from Des Moines to Rome?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Rome (average of $457). Flying from Des Moines to Rome in June is currently the most expensive (average of $1,309). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Rome?

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated June 6, 2026.
See what other customers who have flown with Delta,KLM, andUnited Airlines from Des Moines to Rome have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,395 reviews

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,395 reviews
Delta
7.9
Good
8,395 reviews

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
KLM
7.8
Good
1,526 reviews
Delta
7.9
Good
8,395 reviews

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
9,777 reviews
Delta
7.9
Good
8,395 reviews

Boarding

8.1

Food

7.2

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Rome?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Rome from Des Moines. Booking flights from Des Moines (DSM) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 2 different airlines.

  • How long is the flight from Des Moines to Rome?

    A quick flight from Des Moines to Rome can take about 13h 07m. United Airlines provides one of the quickest options available for as low as $824. The distance from Des Moines to Rome is about 5054 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Rome round-trip?

    Currently priced at $491, United Airlines will fly you from Des Moines to Rome and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $655. These flights start at 47% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to Rome that include hotel bookings?

    Yes. In addition to deals on Des Moines to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Rome.

  • Can I find deals for business class flights from Des Moines to Rome?

    Yes. Cheapflights offers flight deals from Des Moines to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Rome?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Rome (average of $457). Flying from Des Moines to Rome in June is currently the most expensive (average of $1,309). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Montepulciano
Santa Marinella

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Alternative routes for Des Moines to Rome

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Leonardo da Vinci/Fiumicino flights
Des Moines to Leonardo da Vinci/Fiumicino flights

Top 2 airlines flying from Des Moines to Rome

Discover the top 2 airlines that operate flights from Des Moines to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$491Average$752FlexibilityNo cancel feeOn-time69%
DeltaCheapest$655Average$1,084FlexibilityNo cancel feeOn-timeN/A

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