$334+ Cheap flights from Des Moines (DSM) to Italy
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — NAP
Oct 1 — Oct 81
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Italy with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to ItalyExplore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
This Expedia deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:00 am -
2 stops17h 55m
Wed 11/181:15 pm -
2 stops35h 13m
Deal found 8/31![Air Canada logo]()
$709
This Expedia deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:05 am -
2 stops19h 50m
Tue 11/1711:15 am -
2 stops35h 52m
Deal found 8/31![Air Canada logo]()
$714
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/278:00 am -
2 stops19h 05m
Tue 1/1212:55 pm -
2 stops30h 32m
Deal found 8/29![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/253:15 pm -
1 stop16h 00m
Tue 11/103:15 pm -
1 stop14h 44m
Deal found 8/31![United Airlines logo]()
$719
This Air Canada deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/278:00 am -
2 stops19h 05m
Tue 1/1212:55 pm -
3 stops39h 46m
Deal found 8/29![Air Canada logo]()
$720
This Gotogate deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:45 pm -
2 stops32h 20m
Tue 11/106:55 am -
2 stops17h 33m
Deal found 8/31![Multiple Airlines logo]()
$724
This Expedia deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:15 pm -
2 stops21h 30m
Wed 12/91:15 pm -
2 stops32h 04m
Deal found 8/29![Multiple Airlines logo]()
$725
This Air Canada deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:42 pm -
3 stops56h 23m
Tue 1/1212:55 pm -
2 stops41h 21m
Deal found 8/29![Air Canada logo]()
$725
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:55 am -
1 stop14h 50m
Wed 11/181:15 pm -
2 stops35h 13m
Deal found 8/31![United Airlines logo]()
$728
This Ticket deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:27 am -
2 stops15h 53m
Wed 10/2112:20 pm -
2 stops18h 15m
Deal found 8/29![Air Canada logo]()
$728
This Justfly.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:43 pm -
2 stops17h 17m
Fri 11/61:15 pm -
2 stops35h 18m
Deal found 8/30![Multiple Airlines logo]()
$729
This Air France deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:50 pm -
2 stops14h 05m
Tue 11/1010:55 am -
2 stops16h 45m
Deal found 8/31![Multiple Airlines logo]()
$730
Best flights from Des Moines to ItalyDiscover carefully curated flight deals from Des Moines to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
Discover carefully curated flight deals from Des Moines to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/253:15 pm -
1 stop16h 00m
Tue 11/109:45 am -
2 stops20h 14m
Deal found 8/31![United Airlines logo]()
$719
This United deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:00 am -
3 stops19h 55m
Wed 11/181:15 pm -
2 stops40h 44m
Deal found 8/31![Multiple Airlines logo]()
$732
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:42 pm -
2 stops14h 13m
Sat 1/96:30 am -
2 stops16h 27m
Deal found 8/31![Delta logo]()
$798
This Justfly.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:55 pm -
3 stops32h 25m
Wed 10/2112:20 pm -
3 stops42h 15m
Deal found 8/27![Air Canada logo]()
$830
This lastminute.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:24 pm -
2 stops20h 16m
Wed 10/212:20 pm -
2 stops16h 15m
Deal found 8/30![Lufthansa logo]()
$845
This Expedia deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:50 pm -
2 stops37h 40m
Mon 10/199:10 pm -
2 stops32h 23m
Deal found 8/28![Air France logo]()
$959
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:55 am -
1 stop14h 50m
Wed 11/181:15 pm -
2 stops35h 13m
Deal found 8/31![United Airlines logo]()
$728
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:42 pm -
2 stops14h 13m
Sun 1/106:30 am -
2 stops21h 22m
Deal found 8/29![Delta logo]()
$798
This Air Canada deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:27 am -
3 stops15h 53m
Wed 10/2112:20 pm -
3 stops29h 11m
Deal found 8/29![Multiple Airlines logo]()
$800
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:27 pm -
1 stop15h 28m
Tue 11/1711:15 am -
2 stops37h 13m
Deal found 8/31![United Airlines logo]()
$732
This Expedia deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:55 pm -
2 stops20h 05m
Tue 10/202:10 pm -
2 stops16h 25m
Deal found 8/29![Lufthansa logo]()
$872
This KLM deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:35 am -
1 stop20h 50m
Wed 10/216:45 am -
2 stops17h 10m
Deal found 8/30![Multiple Airlines logo]()
$809
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/245:25 am -
2 stops21h 35m
Thu 1/76:30 am -
2 stops21h 22m
Deal found 8/31![Delta logo]()
$828
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/19:37 am -
2 stops19h 43m
Fri 2/56:25 am -
2 stops21h 52m
Deal found 8/27![United Airlines logo]()
$762
This Air Canada deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:26 pm -
3 stops21h 44m
Tue 10/206:00 am -
3 stops18h 48m
Deal found 8/29![Air Canada logo]()
$936
This Rumbo deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:24 pm -
2 stops20h 11m
Wed 10/211:20 pm -
2 stops17h 15m
Deal found 8/30![Lufthansa logo]()
$872
This Air France deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:03 pm -
2 stops15h 52m
Wed 10/216:40 am -
2 stops17h 15m
Deal found 8/30![Multiple Airlines logo]()
$810
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:31 pm -
2 stops20h 24m
Fri 1/86:30 am -
2 stops16h 27m
Deal found 8/31![Delta logo]()
$828
This Air Canada deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:27 am -
3 stops19h 03m
Thu 10/226:00 am -
3 stops18h 48m
Deal found 8/31![Air Canada logo]()
$942
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/18:00 am -
3 stops16h 55m
Fri 2/51:15 pm -
2 stops28h 29m
Deal found 8/28![United Airlines logo]()
$780
This Expedia deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:55 pm -
2 stops40h 15m
Mon 10/197:05 pm -
2 stops33h 18m
Deal found 8/28![Lufthansa logo]()
$894
This Air France deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:03 pm -
2 stops15h 52m
Thu 10/226:40 am -
2 stops17h 15m
Deal found 8/31![Multiple Airlines logo]()
$857
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:00 am -
3 stops17h 55m
Sun 11/151:15 pm -
2 stops35h 13m
Deal found 8/31![United Airlines logo]()
$781
This Delta deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:48 pm -
2 stops18h 32m
Fri 11/276:10 am -
2 stops17h 39m
Deal found 8/29![Delta logo]()
$866
This lastminute.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:55 pm -
2 stops14h 45m
Thu 10/226:00 am -
2 stops24h 35m
Deal found 8/31![Lufthansa logo]()
$899
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/278:00 am -
2 stops19h 05m
Sun 1/1012:55 pm -
2 stops17h 21m
Deal found 8/31![United Airlines logo]()
$789
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:50 pm -
2 stops18h 55m
Tue 10/276:30 am -
2 stops21h 13m
Deal found 8/30![Delta logo]()
$869
This Expedia deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:55 pm -
2 stops14h 45m
Fri 10/232:20 pm -
2 stops34h 28m
Deal found 9/1![Lufthansa logo]()
$914
This Air Canada deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:00 am -
3 stops18h 40m
Fri 11/206:30 am -
3 stops22h 25m
Deal found 8/27![Air Canada logo]()
$1,123
This Flysmarter deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:24 pm -
3 stops17h 06m
Thu 10/229:55 am -
2 stops19h 20m
Deal found 8/31![Multiple Airlines logo]()
$931
Last-minute flights from Des Moines to ItalyDiscover last-minute flight deals from Des Moines to Italy. Data last updated September 1, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Italy. Data last updated September 1, 2026 and is based on user searches.
This Flighttix deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:27 am -
2 stops15h 53m
Tue 10/2012:20 pm -
2 stops18h 15m
Deal found 8/29![Air Canada logo]()
$769
This Ticket deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:27 am -
2 stops15h 53m
Wed 10/2112:20 pm -
2 stops18h 15m
Deal found 8/29![Air Canada logo]()
$728
This Ticket deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:27 am -
1 stop14h 58m
Wed 10/216:45 am -
2 stops17h 10m
Deal found 8/29![Air France logo]()
$764
This Ticket deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:50 pm -
2 stops13h 05m
Wed 10/2112:25 pm -
2 stops17h 08m
Deal found 8/29![Air France logo]()
$770
This Flighttix deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:27 am -
2 stops15h 53m
Wed 10/213:20 pm -
1 stop13h 03m
Deal found 8/30![Multiple Airlines logo]()
$779
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/253:15 pm -
1 stop16h 00m
Tue 11/103:15 pm -
1 stop14h 44m
Deal found 8/31![United Airlines logo]()
$719
This Gotogate deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:45 pm -
2 stops32h 20m
Tue 11/106:55 am -
2 stops17h 33m
Deal found 8/31![Multiple Airlines logo]()
$724
This Air France deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:50 pm -
2 stops14h 05m
Tue 11/1010:55 am -
2 stops16h 45m
Deal found 8/31![Multiple Airlines logo]()
$730
This Justfly.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:43 pm -
2 stops17h 17m
Fri 11/61:15 pm -
2 stops35h 18m
Deal found 8/30![Multiple Airlines logo]()
$729
This FlightHub deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:43 pm -
2 stops17h 17m
Fri 11/67:05 am -
2 stops21h 50m
Deal found 8/31![Lufthansa logo]()
$743
This KLM deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:03 pm -
1 stop14h 17m
Fri 11/610:00 am -
1 stop17h 40m
Deal found 8/30![KLM logo]()
$748
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
3 stops17h 55m
Fri 11/67:05 am -
2 stops21h 50m
Deal found 8/30![United Airlines logo]()
$751
One-way flights from Des Moines to ItalySearch for one-way flight options from Des Moines to Italy. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
Search for one-way flight options from Des Moines to Italy. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:57 pm -
2 stops57h 03m
Deal found 8/29![Multiple Airlines logo]()
$334
This SmartFares deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/288:15 pm -
2 stops29h 40m
Deal found 8/31![Air Canada logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:25 am -
3 stops29h 45m
Deal found 8/29![Multiple Airlines logo]()
$346
This lol.travel deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:45 am -
2 stops25h 10m
Deal found 8/28![Finnair logo]()
$348
This Booking.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:25 am -
2 stops20h 30m
Deal found 8/28![British Airways logo]()
$350
This Expedia deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/811:35 am -
1 stop16h 45m
Deal found 8/31![KLM logo]()
$355
This Expedia deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:20 am -
1 stop19h 55m
Deal found 8/28![KLM logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:43 am -
3 stops50h 22m
Deal found 8/29![Multiple Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:00 am -
3 stops16h 55m
Deal found 8/28![United Airlines logo]()
$360
This Expedia deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:27 pm -
1 stop32h 48m
Deal found 8/28![KLM logo]()
$362
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/286:15 am -
3 stops28h 45m
Deal found 8/31![United Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
3 stops48h 12m
Deal found 8/28![Multiple Airlines logo]()
$368
Find flight deals from Des Moines to Italy
Keep the following information in mind while searching for Des Moines to Italy flight deals. Data was last updated September 1, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $709 (Expedia) |
One-way from | $334 (Kiwi.com) |
Popular in | June |
Cheapest in | December |
Average price | $1,039 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
Use the filters below to find and compare flights from Des Moines to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesMilan
DSM Des Moines - MXP Milan Malpensa
DSMMXP
Des Moines
Sun 10/25
3:15 pm-1:15 pm
1 stop16h 00m
Milan Malpensa
Tue 11/10
9:45 am-10:59 pm
2 stops20h 14m
$719
Des MoinesRome
DSM Des Moines - FCO Rome Fiumicino
DSMFCO
Des Moines
Sun 11/8
9:55 am-7:45 am
1 stop14h 50m
Rome Fiumicino
Wed 11/18
1:15 pm-5:28 pm
2 stops35h 13m
$728
Des MoinesRome
DSM Des Moines - FCO Rome Fiumicino
DSMFCO
Des Moines
Sun 11/8
8:00 am-10:55 am
3 stops19h 55m
Rome Fiumicino
Wed 11/18
1:15 pm-10:59 pm
2 stops40h 44m
$732
Des MoinesRome
DSM Des Moines - FCO Rome Fiumicino
DSMFCO
Des Moines
Sun 11/8
1:27 pm-11:55 am
1 stop15h 28m
Rome Fiumicino
Tue 11/17
11:15 am-5:28 pm
2 stops37h 13m
$732
Des MoinesMilan
DSM Des Moines - LIN Milan Linate
DSMLIN
Des Moines
Mon 2/1
9:37 am-12:20 pm
2 stops19h 43m
Milan Linate
Fri 2/5
6:25 am-9:17 pm
2 stops21h 52m
$762
Des MoinesRome
DSM Des Moines - FCO Rome Fiumicino
DSMFCO
Des Moines
Mon 2/1
8:00 am-7:55 am
3 stops16h 55m
Rome Fiumicino
Fri 2/5
1:15 pm-10:44 am
2 stops28h 29m
$780
Des MoinesRome
DSM Des Moines - FCO Rome Fiumicino
DSMFCO
Des Moines
Sun 11/8
8:00 am-8:55 am
3 stops17h 55m
Rome Fiumicino
Sun 11/15
1:15 pm-5:28 pm
2 stops35h 13m
$781
Des MoinesMilan
DSM Des Moines - MXP Milan Malpensa
DSMMXP
Des Moines
Sun 12/27
8:00 am-10:05 am
2 stops19h 05m
Milan Malpensa
Sun 1/10
12:55 pm-11:16 pm
2 stops17h 21m
$789
Quickest round-trip
Des MoinesMilan
DSM Des Moines - LIN Milan Linate
DSMLIN
Des Moines
Sun 12/27
6:42 pm-3:55 pm
2 stops14h 13m
Milan Linate
Sat 1/9
6:30 am-3:57 pm
2 stops16h 27m
$798
Des MoinesMilan
DSM Des Moines - LIN Milan Linate
DSMLIN
Des Moines
Sun 12/27
6:42 pm-3:55 pm
2 stops14h 13m
Milan Linate
Sun 1/10
6:30 am-8:52 pm
2 stops21h 22m
$798
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.
DSM-MXP
DSM-FCO
DSM-LIN
DSM-VCE
DSM-TRN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Italy
DSM-IT0
DSM-MXP
DSM-FCO
DSM-LIN
DSM-VCE
What is the cheapest month to book a flight from Des Moines to Italy?
Currently, November is the cheapest month in which you can book a flight from Des Moines to Italy (average of $712). Flying from Des Moines to Italy in December is currently the most expensive (average of $1,472). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Italy
Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated September 1, 2026.
Peruse reviews from past customers who have flown with KLM,Delta, andAir France from Des Moines to Italy to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.7
Boarding
7.8
Food
7.3
Overall
7.8
Entertainment
7.2
Crew
8.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Comfort
7.7
Boarding
7.8
Food
7.3
Overall
7.8
Entertainment
7.2
Crew
8.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Comfort
7.7
Boarding
7.8
Food
7.3
Overall
7.8
Entertainment
7.2
Crew
8.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Comfort
7.7
Boarding
7.8
Food
7.3
Overall
7.8
Entertainment
7.2
Crew
8.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Comfort
7.7
Boarding
7.8
Food
7.3
Overall
7.8
Entertainment
7.2
Crew
8.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Comfort
7.7
Boarding
7.8
Food
7.3
Overall
7.8
Entertainment
7.2
Crew
8.4
Reviews
1 / 20
4.0
OkayAbhisek,Aug 2026
JFK - AMS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Italy
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Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Italy, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Italy flights
Browse other Des Moines and Italy flight options. Last updated on September 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 2 airlines flying from Des Moines to Italy
Discover the top 2 airlines that operate flights from Des Moines to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$491 | Average$752 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$655 | Average$1,248 | FlexibilityNo cancel fee | On-timeN/A |