$318+ Cheap flights from Des Moines (DSM) to Italy
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — NAP
Aug 4 — Aug 111
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to ItalyExplore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 5, 2026.
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 5, 2026.
This Air Canada deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:52 pm
DSM
- MXP
2 stops32h 13m
Air Canada
Wed 12/1612:55 pm
MXP
- DSM
2 stops32h 16m
Air Canada
Deal found 6/30![Air Canada logo]()
$725
This Justfly.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:15 pm
DSM
- MXP
3 stops54h 50m
Air Canada
Wed 12/1612:55 pm
MXP
- DSM
2 stops41h 45m
Air Canada
Deal found 6/30![Air Canada logo]()
$736
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:25 am
DSM
- MXP
1 stop19h 25m
Delta
Thu 12/171:05 pm
MXP
- DSM
1 stop16h 24m
Delta
Deal found 6/30![Delta logo]()
$742
This FlightHub deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:24 pm
DSM
- MXP
2 stops20h 16m
Multiple Airlines
Wed 10/2112:20 pm
MXP
- DSM
2 stops29h 11m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:30 pm
DSM
- MXP
1 stop33h 40m
Delta
Thu 12/171:05 pm
MXP
- DSM
1 stop16h 24m
Delta
Deal found 6/30![Delta logo]()
$748
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:25 am
DSM
- MXP
2 stops19h 35m
Delta
Tue 12/1512:00 pm
MXP
- DSM
1 stop35h 04m
Delta
Deal found 6/30![Delta logo]()
$752
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:25 am
DSM
- LIN
2 stops18h 20m
Delta
Wed 12/166:30 am
LIN
- DSM
2 stops18h 12m
Delta
Deal found 6/30![Delta logo]()
$753
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:25 am
DSM
- MXP
1 stop19h 25m
Delta
Fri 12/1111:00 am
MXP
- DSM
2 stops18h 29m
Delta
Deal found 6/30![Delta logo]()
$753
This Expedia deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:52 pm
DSM
- FCO
2 stops33h 03m
Air Canada
Thu 11/511:15 am
FCO
- DSM
2 stops32h 21m
Air Canada
Deal found 7/3![Air Canada logo]()
$754
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:37 am
DSM
- FCO
1 stop16h 08m
United Airlines
Thu 11/511:15 am
FCO
- DSM
2 stops34h 04m
United Airlines
Deal found 7/3![United Airlines logo]()
$759
This United deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:00 am
DSM
- FCO
3 stops20h 55m
Multiple Airlines
Thu 11/511:15 am
FCO
- DSM
2 stops32h 21m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$764
This Cheapflightsfares deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:52 pm
DSM
- FCO
2 stops22h 08m
Lufthansa
Thu 11/57:05 am
FCO
- DSM
2 stops21h 30m
Lufthansa
Deal found 7/2![Lufthansa logo]()
$769
Best flights from Des Moines to ItalyDiscover carefully curated flight deals from Des Moines to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 5, 2026.
Discover carefully curated flight deals from Des Moines to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 5, 2026.
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:50 pm
DSM
- MXP
1 stop11h 30m
United Airlines
Wed 8/1912:20 pm
MXP
- DSM
2 stops32h 56m
United Airlines
Deal found 7/3![United Airlines logo]()
$788
This oojo deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:54 pm
DSM
- FLR
2 stops20h 46m
Scandinavian Airlines
Fri 8/217:55 pm
FLR
- DSM
2 stops33h 42m
Scandinavian Airlines
Deal found 6/30![Scandinavian Airlines logo]()
$796
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:50 pm
DSM
- LIN
2 stops15h 55m
Lufthansa
Wed 8/196:50 am
LIN
- DSM
2 stops17h 38m
Lufthansa
Deal found 7/1![Lufthansa logo]()
$809
This Air France deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:30 pm
DSM
- LIN
2 stops13h 25m
Multiple Airlines
Wed 8/1911:00 am
LIN
- DSM
2 stops16h 39m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$811
This KLM deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:28 am
DSM
- FCO
1 stop13h 07m
KLM
Tue 8/256:30 am
FCO
- DSM
2 stops14h 34m
KLM
Deal found 7/4![KLM logo]()
$815
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:30 pm
DSM
- LIN
2 stops13h 25m
Delta
Wed 8/196:40 am
LIN
- DSM
2 stops20h 59m
Delta
Deal found 6/30![Delta logo]()
$819
This Air Canada deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:32 am
DSM
- TRN
3 stops18h 48m
Air Canada
Tue 8/256:00 am
TRN
- DSM
3 stops18h 18m
Air Canada
Deal found 7/4![Air Canada logo]()
$872
This Air France deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:28 am
DSM
- VCE
1 stop14h 27m
Air France
Mon 8/2411:05 am
VCE
- DSM
1 stop18h 32m
Air France
Deal found 7/3![Air France logo]()
$933
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:21 pm
DSM
- MXP
1 stop16h 59m
United Airlines
Tue 8/2512:20 pm
MXP
- DSM
2 stops29h 06m
United Airlines
Deal found 7/4![United Airlines logo]()
$788
This Air France deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:30 pm
DSM
- LIN
2 stops13h 25m
Multiple Airlines
Wed 8/1911:00 am
LIN
- DSM
2 stops16h 39m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$812
This KLM deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:40 am
DSM
- MXP
1 stop20h 45m
KLM
Mon 8/2411:40 am
MXP
- DSM
1 stop17h 57m
KLM
Deal found 7/3![KLM logo]()
$847
This Expedia deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:21 pm
DSM
- LIN
2 stops21h 09m
Lufthansa
Mon 8/246:15 pm
LIN
- DSM
2 stops30h 03m
Lufthansa
Deal found 7/3![Lufthansa logo]()
$852
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:35 pm
DSM
- FLR
2 stops15h 15m
Delta
Sun 8/236:30 am
FLR
- DSM
2 stops21h 09m
Delta
Deal found 7/2![Delta logo]()
$869
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
DSM
- MXP
1 stop24h 20m
United Airlines
Wed 8/1912:20 pm
MXP
- DSM
2 stops53h 32m
United Airlines
Deal found 7/2![United Airlines logo]()
$799
This KLM deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:35 pm
DSM
- MXP
1 stop31h 50m
KLM
Thu 8/2011:40 am
MXP
- DSM
1 stop17h 57m
KLM
Deal found 6/30![KLM logo]()
$852
This Cheapflightsfares deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:20 pm
DSM
- FLR
2 stops21h 55m
Lufthansa
Fri 8/216:30 am
FLR
- DSM
2 stops17h 58m
Lufthansa
Deal found 7/1![Lufthansa logo]()
$852
This Air France deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:30 pm
DSM
- FLR
2 stops13h 55m
Multiple Airlines
Fri 8/2111:20 am
FLR
- DSM
2 stops16h 19m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$853
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:54 pm
DSM
- FCO
1 stop12h 56m
Delta
Fri 8/216:30 am
FCO
- DSM
2 stops21h 09m
Delta
Deal found 6/30![Delta logo]()
$873
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
DSM
- FCO
2 stops24h 15m
United Airlines
Thu 8/2011:30 am
FCO
- DSM
2 stops33h 46m
United Airlines
Deal found 7/3![United Airlines logo]()
$803
This Cheapflightsfares deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/161:21 pm
DSM
- FLR
2 stops20h 14m
Lufthansa
Sun 8/236:30 am
FLR
- DSM
2 stops21h 53m
Lufthansa
Deal found 7/2![Lufthansa logo]()
$852
This Air France deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:56 pm
DSM
- FLR
2 stops13h 29m
Multiple Airlines
Sun 8/236:30 am
FLR
- DSM
2 stops17h 41m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$857
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:40 am
DSM
- FCO
1 stop22h 10m
Delta
Mon 8/249:00 am
FCO
- DSM
1 stop18h 39m
Delta
Deal found 7/2![Delta logo]()
$874
This KLM deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:40 am
DSM
- VCE
1 stop20h 15m
KLM
Tue 8/2511:05 am
VCE
- DSM
1 stop18h 32m
KLM
Deal found 7/4![KLM logo]()
$875
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:21 pm
DSM
- FCO
1 stop11h 34m
United Airlines
Fri 8/2811:30 am
FCO
- DSM
2 stops33h 46m
United Airlines
Deal found 6/30![United Airlines logo]()
$803
This Cheapflightsfares deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:21 pm
DSM
- TRN
2 stops16h 59m
Lufthansa
Tue 8/256:00 am
TRN
- DSM
2 stops22h 23m
Lufthansa
Deal found 7/4![Lufthansa logo]()
$863
This Air France deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:30 pm
DSM
- LIN
2 stops13h 25m
Multiple Airlines
Thu 8/206:40 am
LIN
- DSM
2 stops17h 31m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$863
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:55 am
DSM
- FCO
2 stops17h 40m
Delta
Sun 8/236:30 am
FCO
- DSM
2 stops21h 09m
Delta
Deal found 7/2![Delta logo]()
$877
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:00 am
DSM
- MXP
2 stops21h 20m
United Airlines
Mon 8/2410:40 am
MXP
- DSM
2 stops41h 43m
United Airlines
Deal found 7/3![United Airlines logo]()
$816
This Ticket deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:56 pm
DSM
- VCE
2 stops15h 49m
KLM
Fri 8/2111:45 am
VCE
- DSM
2 stops15h 54m
KLM
Deal found 6/30![KLM logo]()
$908
This Air France deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:30 pm
DSM
- LIN
2 stops13h 25m
Multiple Airlines
Mon 8/2411:00 am
LIN
- DSM
2 stops16h 39m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$865
Last-minute flights from Des Moines to ItalyDiscover last-minute flight deals from Des Moines to Italy. Data last updated July 5, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Italy. Data last updated July 5, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:50 pm
DSM
- MXP
1 stop11h 30m
United Airlines
Wed 8/1912:20 pm
MXP
- DSM
2 stops32h 56m
United Airlines
Deal found 7/3![United Airlines logo]()
$788
This Gotogate deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:00 am
DSM
- MXP
2 stops21h 20m
Air Canada
Wed 8/1912:20 pm
MXP
- DSM
2 stops32h 56m
Air Canada
Deal found 7/3![Air Canada logo]()
$791
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:33 pm
DSM
- MXP
2 stops16h 12m
American Airlines
Wed 8/192:20 pm
MXP
- DSM
1 stop14h 46m
American Airlines
Deal found 7/4![American Airlines logo]()
$801
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
DSM
- MXP
1 stop24h 20m
United Airlines
Wed 8/1912:20 pm
MXP
- DSM
2 stops55h 12m
United Airlines
Deal found 7/1![United Airlines logo]()
$799
This Flighttix deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:21 pm
DSM
- FCO
1 stop11h 34m
Lufthansa
Wed 8/198:00 am
FCO
- DSM
2 stops16h 28m
Lufthansa
Deal found 7/4![Lufthansa logo]()
$802
This oojo deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/142:54 pm
DSM
- FLR
2 stops20h 46m
Scandinavian Airlines
Fri 8/217:55 pm
FLR
- DSM
2 stops33h 42m
Scandinavian Airlines
Deal found 6/30![Scandinavian Airlines logo]()
$796
This Ticket deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:32 am
DSM
- FCO
2 stops17h 13m
Air Canada
Fri 8/2111:30 am
FCO
- DSM
2 stops29h 56m
Air Canada
Deal found 6/30![Air Canada logo]()
$799
This Expedia deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:30 pm
DSM
- LIN
2 stops15h 25m
KLM
Mon 8/2410:10 pm
LIN
- DSM
2 stops22h 54m
KLM
Deal found 7/3![KLM logo]()
$777
This Ticket deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
DSM
- MXP
2 stops21h 20m
Air Canada
Tue 8/2512:20 pm
MXP
- DSM
2 stops29h 06m
Air Canada
Deal found 7/4![Air Canada logo]()
$766
This Ticket deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:56 pm
DSM
- LIN
2 stops12h 59m
Multiple Airlines
Tue 8/256:40 am
LIN
- DSM
2 stops14h 24m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$789
This Bravofly deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:20 pm
DSM
- FCO
2 stops35h 40m
Lufthansa
Tue 8/256:50 am
FCO
- DSM
2 stops17h 28m
Lufthansa
Deal found 7/4![Lufthansa logo]()
$793
This Flighttix deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:32 am
DSM
- FCO
2 stops17h 13m
Multiple Airlines
Tue 8/256:50 am
FCO
- DSM
2 stops17h 28m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$795
One-way flights from Des Moines to ItalySearch for one-way flight options from Des Moines to Italy. Find affordable one-way fares based on user searches. Data last updated July 5, 2026.
Search for one-way flight options from Des Moines to Italy. Find affordable one-way fares based on user searches. Data last updated July 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/309:28 am
DSM
- MXP
3 stops30h 52m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:30 am
DSM
- FCO
3 stops35h 55m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$392
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:30 am
DSM
- LIN
2 stops23h 30m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:19 pm
DSM
- MXP
3 stops49h 41m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:30 am
DSM
- FCO
3 stops29h 05m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:07 pm
DSM
- FCO
3 stops37h 28m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$407
This oojo deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:33 pm
DSM
- FCO
2 stops17h 47m
British Airways
Deal found 7/1![British Airways logo]()
$445
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:30 am
DSM
- FLR
3 stops51h 25m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$454
This KLM deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1611:28 am
DSM
- FCO
1 stop13h 07m
KLM
Deal found 7/1![KLM logo]()
$457
This oojo deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:21 pm
DSM
- FCO
2 stops13h 39m
Lufthansa
Deal found 7/3![Lufthansa logo]()
$458
This KLM deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:40 am
DSM
- VCE
1 stop20h 15m
KLM
Deal found 7/3![KLM logo]()
$458
This KLM deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:40 am
DSM
- FCO
1 stop18h 55m
KLM
Deal found 7/2![KLM logo]()
$459
Find flight deals from Des Moines to Italy
Keep the following information in mind while searching for Des Moines to Italy flight deals. Data was last updated July 5, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $725 (Air Canada) |
One-way from | $318 (Kiwi.com) |
Popular in | June |
Cheapest in | December |
Average price | $980 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 5, 2026.
Use the filters below to find and compare flights from Des Moines to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesMilan
DSM - MXP
DSMMXP
Des Moines
Mon 8/3
6:50 pm-1:20 pm
1 stop11h 30m
Milan Malpensa
Wed 8/19
12:20 pm-2:16 pm
2 stops32h 56m
$788
Des MoinesMilan
DSM - MXP
DSMMXP
Des Moines
Tue 8/18
1:21 pm-1:20 pm
1 stop16h 59m
Milan Malpensa
Tue 8/25
12:20 pm-10:26 am
2 stops29h 06m
$788
Des MoinesFlorence
DSM - FLR
DSMFLR
Des Moines
Fri 8/14
2:54 pm-6:40 pm
2 stops20h 46m
Florence Peretola
Fri 8/21
7:55 pm-10:37 pm
2 stops33h 42m
$796
Des MoinesMilan
DSM - MXP
DSMMXP
Des Moines
Wed 8/12
6:00 am-1:20 pm
1 stop24h 20m
Milan Malpensa
Wed 8/19
12:20 pm-10:52 am
2 stops53h 32m
$799
Des MoinesRome
DSM - FCO
DSMFCO
Des Moines
Tue 8/11
6:00 am-1:15 pm
2 stops24h 15m
Rome Fiumicino
Thu 8/20
11:30 am-2:16 pm
2 stops33h 46m
$803
Des MoinesRome
DSM - FCO
DSMFCO
Des Moines
Mon 8/17
1:21 pm-7:55 am
1 stop11h 34m
Rome Fiumicino
Fri 8/28
11:30 am-2:16 pm
2 stops33h 46m
$803
Des MoinesMilan
DSM - LIN
DSMLIN
Des Moines
Mon 8/3
6:50 pm-5:45 pm
2 stops15h 55m
Milan Linate
Wed 8/19
6:50 am-5:28 pm
2 stops17h 38m
$809
Des MoinesMilan
DSM - LIN
DSMLIN
Des Moines
Wed 8/12
5:30 pm-1:55 pm
2 stops13h 25m
Milan Linate
Wed 8/19
11:00 am-8:39 pm
2 stops16h 39m
$811
Des MoinesMilan
DSM - LIN
DSMLIN
Des Moines
Mon 8/3
5:30 pm-1:55 pm
2 stops13h 25m
Milan Linate
Wed 8/19
11:00 am-8:39 pm
2 stops16h 39m
$812
Quickest round-trip
Des MoinesRome
DSM - FCO
DSMFCO
Des Moines
Tue 8/18
11:28 am-7:35 am
1 stop13h 07m
Rome Fiumicino
Tue 8/25
6:30 am-2:04 pm
2 stops14h 34m
$815
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.
DSM-MXP
DSM-FCO
DSM-LIN
DSM-VCE
DSM-FLR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Italy
DSM-IT0
DSM-MXP
DSM-FCO
DSM-LIN
DSM-VCE
What is the cheapest month to book a flight from Des Moines to Italy?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $457). Flying from Des Moines to Italy in June is currently the most expensive (average of $675). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Italy
Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated July 5, 2026.
Peruse reviews from past customers who have flown with KLM,Delta, andAir France from Des Moines to Italy to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.4
Boarding
7.8
Entertainment
7.2
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Crew
8.4
Boarding
7.8
Entertainment
7.2
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Crew
8.4
Boarding
7.8
Entertainment
7.2
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Crew
8.4
Boarding
7.8
Entertainment
7.2
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Crew
8.4
Boarding
7.8
Entertainment
7.2
Overall
7.8
Comfort
7.7
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Italy
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Complete your trip
Complete your trip to Italy by adding a car rental and/or hotel reservation to your travel itinerary.
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Des Moines and Italy flights
Browse other Des Moines and Italy flight options. Last updated on July 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to Italy regions
Consider these flights traveling to Italy regions.
Top 2 airlines flying from Des Moines to Italy
Discover the top 2 airlines that operate flights from Des Moines to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$491 | Average$752 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$655 | Average$1,246 | FlexibilityNo cancel fee | On-timeN/A |