$515+ Cheap flights from Des Moines (DSM) to Italy
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — FCO
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to ItalyExplore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:58 pm -
2 stops17h 37m
Tue 12/81:10 pm -
2 stops18h 15m
Deal found 10/17![American Airlines logo]()
$667
This KLM deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:39 am -
1 stop19h 36m
Tue 11/2410:25 am -
2 stops17h 48m
Deal found 10/18![Multiple Airlines logo]()
$669
This Air France deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:58 pm -
1 stop13h 22m
Tue 12/810:00 am -
1 stop13h 49m
Deal found 10/17![Multiple Airlines logo]()
$670
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:58 pm -
2 stops17h 57m
Tue 11/241:10 pm -
1 stop17h 13m
Deal found 10/18![American Airlines logo]()
$673
This KLM deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
1 stop19h 45m
Wed 11/2510:00 am -
1 stop17h 43m
Deal found 10/16![KLM logo]()
$676
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:58 pm -
2 stops17h 57m
Thu 11/261:10 pm -
2 stops28h 38m
Deal found 10/18![American Airlines logo]()
$678
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:41 am -
2 stops18h 34m
Tue 12/81:30 pm -
1 stop16h 08m
Deal found 10/17![Delta logo]()
$680
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
2 stops19h 15m
Thu 11/2610:00 am -
2 stops19h 35m
Deal found 10/17![Delta logo]()
$681
This Booking.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:58 pm -
2 stops15h 22m
Wed 11/2512:15 pm -
2 stops19h 04m
Deal found 10/16![British Airways logo]()
$685
This FlightHub deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:31 am -
2 stops21h 04m
Tue 12/1510:40 am -
2 stops20h 45m
Deal found 10/16![British Airways logo]()
$708
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1111:38 am -
2 stops17h 57m
Wed 12/1610:25 am -
2 stops21h 08m
Deal found 10/17![American Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:11 am -
2 stops17h 54m
Mon 12/1410:25 am -
2 stops19h 35m
Deal found 10/16![American Airlines logo]()
$715
Best flights from Des Moines to ItalyDiscover carefully curated flight deals from Des Moines to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Des Moines to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This Expedia deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1910:26 am -
2 stops18h 04m
Sat 1/307:25 am -
2 stops18h 42m
Deal found 10/18![British Airways logo]()
$718
This KLM deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:20 am -
1 stop19h 55m
Thu 12/101:30 pm -
1 stop16h 08m
Deal found 10/19![KLM logo]()
$719
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/195:45 am -
2 stops21h 05m
Sat 1/3012:55 pm -
1 stop16h 34m
Deal found 10/18![Delta logo]()
$721
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/19:25 am -
2 stops17h 40m
Fri 2/59:15 am -
2 stops20h 59m
Deal found 10/18![United Airlines logo]()
$743
This Expedia deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/127:00 pm -
3 stops32h 05m
Sun 2/216:55 am -
2 stops21h 20m
Deal found 10/18![Multiple Airlines logo]()
$753
This Justfly.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/127:00 pm -
3 stops32h 05m
Sun 2/2112:55 pm -
3 stops41h 33m
Deal found 10/18![Air Canada logo]()
$759
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/179:45 am -
3 stops18h 50m
Thu 2/2512:35 pm -
2 stops19h 05m
Deal found 10/15![American Airlines logo]()
$761
This FlightHub deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/116:45 pm -
2 stops16h 00m
Wed 4/2112:40 pm -
2 stops17h 21m
Deal found 10/17![Lufthansa logo]()
$767
This Expedia deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1411:04 am -
2 stops41h 01m
Sat 4/248:35 pm -
2 stops32h 54m
Deal found 10/14![Scandinavian Airlines logo]()
$839
This KLM deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2910:24 am -
2 stops25h 21m
Sun 12/611:20 am -
2 stops18h 18m
Deal found 10/15![KLM logo]()
$722
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3010:24 am -
1 stop16h 11m
Mon 12/710:00 am -
2 stops18h 31m
Deal found 10/16![Delta logo]()
$730
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:30 pm -
2 stops31h 25m
Sat 1/3011:15 am -
2 stops32h 02m
Deal found 10/16![United Airlines logo]()
$744
This KLM deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:53 pm -
2 stops16h 02m
Wed 12/166:30 am -
2 stops17h 19m
Deal found 10/17![Multiple Airlines logo]()
$769
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:01 am -
2 stops17h 19m
Thu 12/1010:00 am -
2 stops19h 38m
Deal found 10/19![Delta logo]()
$731
This FlightHub deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:18 pm -
2 stops15h 37m
Thu 12/106:25 am -
2 stops22h 00m
Deal found 10/16![Lufthansa logo]()
$819
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/18:00 am -
2 stops22h 50m
Fri 2/56:30 am -
2 stops23h 00m
Deal found 10/14![United Airlines logo]()
$745
This Air Canada deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
3 stops18h 40m
Wed 11/256:30 am -
3 stops19h 46m
Deal found 10/19![Air Canada logo]()
$845
This Finnair deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:45 am -
1 stop18h 00m
Wed 11/116:40 pm -
2 stops35h 25m
Deal found 10/16![Multiple Airlines logo]()
$772
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:05 pm -
2 stops18h 30m
Thu 12/106:00 am -
2 stops20h 01m
Deal found 10/18![American Airlines logo]()
$880
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/118:00 am -
1 stop22h 20m
Wed 4/2112:10 pm -
2 stops33h 01m
Deal found 10/17![United Airlines logo]()
$747
This KLM deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:22 am -
1 stop16h 13m
Thu 11/1210:00 am -
1 stop17h 43m
Deal found 10/18![KLM logo]()
$830
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:58 pm -
1 stop12h 47m
Tue 12/812:55 pm -
1 stop16h 43m
Deal found 10/15![Delta logo]()
$760
This Air Canada deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:22 am -
3 stops18h 28m
Tue 12/87:00 am -
3 stops19h 19m
Deal found 10/19![Air Canada logo]()
$859
This Expedia deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:45 pm -
2 stops14h 20m
Mon 12/77:20 pm -
2 stops28h 54m
Deal found 10/15![Lufthansa logo]()
$864
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/111:22 am -
2 stops17h 58m
Fri 2/56:25 am -
2 stops20h 57m
Deal found 10/14![United Airlines logo]()
$751
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:59 pm -
2 stops15h 56m
Fri 12/116:30 am -
2 stops22h 01m
Deal found 10/15![Delta logo]()
$770
This KLM deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:52 pm -
2 stops36h 23m
Sun 12/611:50 am -
2 stops16h 41m
Deal found 10/14![KLM logo]()
$905
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/29:25 am -
2 stops21h 35m
Fri 2/57:00 am -
2 stops21h 23m
Deal found 10/16![United Airlines logo]()
$762
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:59 pm -
2 stops15h 56m
Tue 12/156:30 am -
2 stops19h 45m
Deal found 10/15![Delta logo]()
$770
This FlightHub deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
2 stops14h 45m
Thu 11/127:05 am -
2 stops21h 50m
Deal found 10/14![Lufthansa logo]()
$1,004
Last-minute flights from Des Moines to ItalyDiscover last-minute flight deals from Des Moines to Italy. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Italy. Data last updated October 19, 2026 and is based on user searches.
This KLM deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:39 am -
1 stop19h 36m
Tue 11/2410:25 am -
2 stops17h 48m
Deal found 10/18![Multiple Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:58 pm -
2 stops17h 57m
Tue 11/241:10 pm -
1 stop17h 13m
Deal found 10/18![American Airlines logo]()
$673
This KLM deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
1 stop19h 45m
Wed 11/2510:00 am -
1 stop17h 43m
Deal found 10/16![KLM logo]()
$676
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:58 pm -
2 stops17h 57m
Thu 11/261:10 pm -
2 stops28h 38m
Deal found 10/18![American Airlines logo]()
$678
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
2 stops19h 15m
Thu 11/2610:00 am -
2 stops19h 35m
Deal found 10/17![Delta logo]()
$681
This Booking.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:58 pm -
2 stops15h 22m
Wed 11/2512:15 pm -
2 stops19h 04m
Deal found 10/16![British Airways logo]()
$685
This FlightHub deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:31 am -
2 stops21h 04m
Tue 12/1510:40 am -
2 stops20h 45m
Deal found 10/16![British Airways logo]()
$708
This FlightHub deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/241:58 pm -
2 stops18h 42m
Sun 12/131:30 pm -
2 stops18h 03m
Deal found 10/16![British Airways logo]()
$724
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:11 am -
2 stops17h 54m
Mon 12/1410:25 am -
2 stops19h 35m
Deal found 10/16![American Airlines logo]()
$715
This KLM deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2910:24 am -
2 stops25h 21m
Sun 12/611:20 am -
2 stops18h 18m
Deal found 10/15![KLM logo]()
$722
This Expedia deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3010:24 am -
1 stop16h 11m
Mon 12/78:45 pm -
2 stops28h 21m
Deal found 10/16![Air France logo]()
$691
This Iberia deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:58 pm -
2 stops16h 57m
Mon 12/74:20 pm -
2 stops33h 41m
Deal found 10/16![Iberia logo]()
$699
One-way flights from Des Moines to ItalySearch for one-way flight options from Des Moines to Italy. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from Des Moines to Italy. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:00 am -
2 stops33h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$515
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/278:43 pm -
3 stops58h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$528
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:13 pm -
3 stops56h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$563
This British Airways deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:31 am -
2 stops19h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![British Airways logo]()
$569
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/275:12 pm -
2 stops15h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![United Airlines logo]()
$572
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:35 am -
3 stops29h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$573
This Expedia deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/249:21 am -
2 stops20h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![British Airways logo]()
$594
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:31 pm -
2 stops18h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$610
This Air Canada deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3011:22 am -
3 stops18h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Air Canada logo]()
$1,073
This British Airways deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/291:58 pm -
2 stops15h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![British Airways logo]()
$7,776
Find flight deals from Des Moines to Italy
Keep the following information in mind while searching for Des Moines to Italy flight deals. Data was last updated October 19, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $667 (American Airlines) |
One-way from | $515 (Kiwi.com) |
Popular in | June |
Cheapest in | December |
Average price | $1,359 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Des Moines to Italy that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesVenice
DSM Des Moines - VCE Venice Marco Polo
DSMVCE
Des Moines
Sat 10/24
9:00 am-1:05 am
2 stops33h 05m
Venice Marco Polo
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$515
Des MoinesBologna
DSM Des Moines - BLQ Bologna Guglielmo Marconi
DSMBLQ
Des Moines
Mon 11/30
9:31 am-11:40 am
2 stops19h 09m
Bologna Guglielmo Marconi
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$569
Des MoinesVenice
DSM Des Moines - VCE Venice Marco Polo
DSMVCE
Des Moines
Sun 12/27
5:12 pm-4:05 pm
2 stops15h 53m
Venice Marco Polo
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$572
Des MoinesVenice
DSM Des Moines - VCE Venice Marco Polo
DSMVCE
Des Moines
Thu 12/10
3:31 pm-4:55 pm
2 stops18h 24m
Venice Marco Polo
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$610
Des MoinesVenice
DSM Des Moines - VCE Venice Marco Polo
DSMVCE
Des Moines
Thu 12/10
2:05 pm-4:55 pm
2 stops19h 50m
Venice Marco Polo
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$613
Des MoinesVenice
DSM Des Moines - VCE Venice Marco Polo
DSMVCE
Des Moines
Sat 10/24
8:00 am-3:00 pm
3 stops24h 00m
Venice Marco Polo
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$617
Des MoinesMilan
DSM Des Moines - LIN Milan Linate
DSMLIN
Des Moines
Tue 1/19
10:26 am-11:30 am
2 stops18h 04m
Milan Linate
Sat 1/30
7:25 am-7:07 pm
2 stops18h 42m
$718
Des MoinesRome
DSM Des Moines - FCO Rome Fiumicino
DSMFCO
Des Moines
Thu 12/3
5:20 am-8:15 am
1 stop19h 55m
Rome Fiumicino
Thu 12/10
1:30 pm-10:38 pm
1 stop16h 08m
$719
Des MoinesMilan
DSM Des Moines - MXP Milan Malpensa
DSMMXP
Des Moines
Tue 1/19
5:45 am-9:50 am
2 stops21h 05m
Milan Malpensa
Sat 1/30
12:55 pm-10:29 pm
1 stop16h 34m
$721
Des MoinesBari
DSM Des Moines - BRI Bari Palese
DSMBRI
Des Moines
Sun 11/29
10:24 am-6:45 pm
2 stops25h 21m
Bari Palese
Sun 12/6
11:20 am-10:38 pm
2 stops18h 18m
$722
Showing 1-10 of 38 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Italy
Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.
DSM-VCE
DSM-BLQ
DSM-FCO
DSM-LIN
DSM-MXP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Italy
DSM-IT0
DSM-VCE
DSM-BLQ
DSM-FCO
DSM-LIN
What is the cheapest month to book a flight from Des Moines to Italy?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Italy (average of $741). Flying from Des Moines to Italy in December is currently the most expensive (average of $1,472). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Italy
Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated October 19, 2026.
Peruse reviews from past customers who have flown with KLM,Delta, andAir France from Des Moines to Italy to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.2
Comfort
7.7
Crew
8.4
Overall
7.8
Food
7.4
Boarding
7.8
Reviews
1 / 20
8.0
ExcellentKushal,Sep 2026
QRO - ATL
Entertainment
7.2
Comfort
7.7
Crew
8.4
Overall
7.8
Food
7.4
Boarding
7.8
Reviews
1 / 20
8.0
ExcellentKushal,Sep 2026
QRO - ATL
Entertainment
7.2
Comfort
7.7
Crew
8.4
Overall
7.8
Food
7.4
Boarding
7.8
Reviews
1 / 20
8.0
ExcellentKushal,Sep 2026
QRO - ATL
Entertainment
7.2
Comfort
7.7
Crew
8.4
Overall
7.8
Food
7.4
Boarding
7.8
Reviews
1 / 20
8.0
ExcellentKushal,Sep 2026
QRO - ATL
Entertainment
7.2
Comfort
7.7
Crew
8.4
Overall
7.8
Food
7.4
Boarding
7.8
Reviews
1 / 20
8.0
ExcellentKushal,Sep 2026
QRO - ATL
Entertainment
7.2
Comfort
7.7
Crew
8.4
Overall
7.8
Food
7.4
Boarding
7.8
Reviews
1 / 20
8.0
ExcellentKushal,Sep 2026
QRO - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Italy
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Complete your trip
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Des Moines and Italy flights
Browse other Des Moines and Italy flight options. Last updated on October 19, 2026.
Popular flight searches
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Fly to Italy regions
Consider these flights traveling to Italy regions.
Top airline flying from Des Moines to Italy
Discover the top airline that operate flights from Des Moines to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$910 | Average$1,248 | FlexibilityNo cancel fee | On-timeN/A |