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Italy

$239+ Cheap flights from Des Moines (DSM) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — NAP
Jan 9 — Jan 161
Fri 1/9
Fri 1/16
1 adult, Economy
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Cheap flight deals from Des Moines to Italy

Cheapest flights from Des Moines to Italy
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 10, 2025.

This FlightHub deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:00 amDSM - MXP
2 stops42h 55mMultiple Airlines
Thu 1/82:40 pmMXP - DSM
2 stops38h 10mMultiple Airlines
Deal found 12/10$716
This Air Canada deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:46 pmDSM - MXP
2 stops32h 09mAir Canada
Thu 1/81:05 pmMXP - DSM
3 stops54h 47mAir Canada
Deal found 12/10$941
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - VCE
2 stops38h 29mUnited Airlines
Tue 1/61:00 pmVCE - DSM
2 stops41h 44mUnited Airlines
Deal found 12/7$1,058
This Expedia deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - VCE
2 stops44h 59mLufthansa
Tue 1/61:50 pmVCE - DSM
2 stops39h 00mLufthansa
Deal found 12/9$1,079
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 pmDSM - LIN
2 stops14h 25mDelta
Tue 12/306:30 amLIN - DSM
2 stops20h 32mDelta
Deal found 12/10$1,131
This KAYAK deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - FLR
2 stops42h 54mLufthansa
Thu 1/15:15 pmFLR - DSM
2 stops35h 25mLufthansa
Deal found 12/10$1,560
This KAYAK deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:35 amDSM - LIN
2 stops18h 15mLufthansa
Fri 12/267:40 pmLIN - DSM
2 stops29h 25mLufthansa
Deal found 12/9$1,915
This Trip.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:35 amDSM - FCO
1 stop22h 55mMultiple Airlines
Fri 1/27:10 pmFCO - DSM
1 stop26h 45mMultiple Airlines
Deal found 12/8$1,936
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:59 amDSM - MXP
2 stops21h 41mDelta
Thu 1/811:05 amMXP - DSM
1 stop32h 09mDelta
Deal found 12/10$2,119
This Ovago deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:35 amDSM - MXP
2 stops18h 00mLufthansa
Fri 12/269:10 amMXP - DSM
2 stops39h 55mLufthansa
Deal found 12/8$2,130
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amDSM - MXP
2 stops18h 30mUnited Airlines
Fri 12/269:10 amMXP - DSM
2 stops36h 23mUnited Airlines
Deal found 12/9$2,269
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:35 pmDSM - MXP
2 stops15h 35mAmerican Airlines
Fri 12/2610:25 amMXP - DSM
2 stops20h 10mAmerican Airlines
Deal found 12/9$2,386

Find flight deals from Des Moines to Italy

Keep the following information in mind while searching for Des Moines to Italy flight deals. Data was last updated December 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$450
(Ticket)

One-way from

$239
(EaseMyTrip)

Popular in

June

Cheapest in

November

Average price

$773
Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.
Search Deals
From Des Moines to Italy
Search Deals
One-way flight from Des Moines to Italy
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($293 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($55 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
Use the filters below to find and compare flights from Des Moines to Italy that are best for you.

Fly from

Des Moines

Fly to

Italy

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Thu 1/22

6:48 pm-4:30 pm

2 stops14h 42m

Florence Peretola

Thu 1/29

6:35 am-5:47 pm

2 stops18h 12m

$459

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Fri 1/23

6:48 pm-6:50 pm

2 stops17h 02m

Milan Linate

Fri 1/30

6:10 am-9:50 pm

2 stops22h 40m

$465

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Fri 1/23

6:48 pm-4:40 pm

2 stops14h 52m

Milan Malpensa

Fri 1/30

1:05 pm-11:44 pm

2 stops17h 39m

$468

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sat 1/24

11:30 am-4:30 pm

2 stops22h 00m

Florence Peretola

Sat 1/31

8:00 am-5:47 pm

2 stops16h 47m

$469

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Thu 1/22

11:30 am-12:35 pm

2 stops18h 05m

Florence Peretola

Thu 1/29

6:35 am-9:50 pm

2 stops22h 15m

$470

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Wed 1/21

6:48 pm-10:45 pm

2 stops20h 57m

Venice Marco Polo

Wed 1/28

10:45 am-10:30 pm

2 stops18h 45m

$472

Des MoinesVenice

DSM - VCE

DSMVCE

Des Moines

Sat 1/24

3:35 pm-12:20 pm

2 stops13h 45m

Venice Marco Polo

Sat 1/31

6:45 am-10:30 pm

2 stops22h 45m

$473

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Thu 1/22

5:30 am-9:55 am

2 stops21h 25m

Milan Malpensa

Thu 1/29

1:05 pm-2:33 pm

2 stops32h 28m

$474

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 1/21

1:35 pm-9:55 am

2 stops37h 20m

Milan Malpensa

Wed 1/28

1:05 pm-2:33 pm

2 stops32h 28m

$474

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Thu 1/22

6:48 pm-7:55 am

2 stops30h 07m

Rome Fiumicino

Thu 1/29

7:05 am-9:50 pm

2 stops21h 45m

$474

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Italy

What is the cheapest month to book a flight from Des Moines to Italy?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $517). Flying from Des Moines to Italy in July is currently the most expensive (average of $1,065). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IT?

Find hourly flight availability from Des Moines to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 10, 2025.

It’s optimal to fly from Des Moines to Italy in the evening. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated December 10, 2025.
Peruse reviews from past customers who have flown with Delta, KLM, and United Airlines from Des Moines to Italy to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,431 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,573 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Italy?

    For a flight from Des Moines to Italy, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Des Moines to Italy?

    For as low as $459, Air France can have you in Italy from Des Moines in 14h 42m. The distance between Des Moines and Italy is about 4923 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Des Moines to Italy?

    While some choose either Des Moines - Milan Malpensa or Des Moines - Milan Linate, Des Moines - Rome Fiumicino is the most popular route from Des Moines to Italy.

  • Can I find deals for flights from Des Moines to Italy that include hotel bookings?

    Yes. In addition to deals on Des Moines to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Italy.

  • Can I find deals for business class flights from Des Moines to Italy?

    Yes. Cheapflights offers flight deals from Des Moines to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Italy?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $517). Flying from Des Moines to Italy in July is currently the most expensive (average of $1,065). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Italy

Discover the top 4 airlines that operate flights from Des Moines to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$641Average$1,291FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$655Average$1,171FlexibilityNo cancel feeOn-time69%
KLMCheapest$680Average$1,090FlexibilityNo cancel feeOn-time75%
LufthansaCheapest$738Average$1,185FlexibilityNo cancel feeOn-time76%

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