$795+ Cheap flights from Italy to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
FCO — DSM
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from Italy to Des MoinesExplore the most affordable flight options available from Italy to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Italy to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:00 pm -
2 stops17h 33m
Sun 11/85:50 pm -
2 stops16h 35m
Deal found 10/19![Delta logo]()
$802
This lol.travel deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:40 pm -
2 stops15h 19m
Sun 11/86:45 pm -
1 stop11h 30m
Deal found 10/19![Lufthansa logo]()
$948
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:20 pm -
1 stop16h 27m
Sat 11/77:23 pm -
2 stops29h 42m
Deal found 10/18![American Airlines logo]()
$989
This Expedia deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:40 pm -
2 stops15h 19m
Sun 11/86:05 am -
3 stops21h 00m
Deal found 10/19![Multiple Airlines logo]()
$1,034
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:20 pm -
1 stop17h 39m
Thu 11/56:00 am -
1 stop19h 05m
Deal found 10/16![American Airlines logo]()
$1,049
This Iberia deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:20 am -
2 stops19h 36m
Thu 11/56:00 am -
2 stops20h 30m
Deal found 10/16![Multiple Airlines logo]()
$1,157
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:45 am -
2 stops16h 31m
Thu 11/59:50 am -
2 stops14h 40m
Deal found 10/16![United Airlines logo]()
$1,341
This Air Canada deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:05 pm -
2 stops28h 27m
Sat 11/79:55 am -
3 stops17h 10m
Deal found 10/18![Multiple Airlines logo]()
$1,355
Best flights from Italy to Des MoinesDiscover carefully curated flight deals from Italy to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Italy to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:00 pm -
2 stops17h 33m
Sun 11/85:50 pm -
2 stops16h 35m
Deal found 10/19![Delta logo]()
$802
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/187:30 am -
2 stops23h 26m
Sun 2/213:55 pm -
2 stops15h 35m
Deal found 10/16![American Airlines logo]()
$898
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/189:55 am -
2 stops17h 45m
Sun 2/218:00 am -
2 stops16h 55m
Deal found 10/14![United Airlines logo]()
$904
This Booking.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:15 pm -
1 stop14h 44m
Sun 11/86:45 pm -
1 stop11h 30m
Deal found 10/19![Lufthansa logo]()
$1,016
This Expedia deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:40 pm -
2 stops15h 19m
Sun 11/86:05 am -
3 stops21h 00m
Deal found 10/19![Multiple Airlines logo]()
$1,034
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:20 pm -
1 stop16h 27m
Sat 11/77:23 pm -
2 stops29h 42m
Deal found 10/18![American Airlines logo]()
$989
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:20 pm -
1 stop17h 39m
Thu 11/56:00 am -
1 stop19h 05m
Deal found 10/16![American Airlines logo]()
$1,049
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:45 am -
2 stops16h 31m
Thu 11/59:50 am -
2 stops14h 40m
Deal found 10/16![United Airlines logo]()
$1,341
This Air Canada deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:05 pm -
2 stops28h 27m
Sat 11/79:55 am -
3 stops17h 10m
Deal found 10/18![Multiple Airlines logo]()
$1,355
This Emirates deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Emirates is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/291:55 pm -
2 stops36h 21m
Sun 12/63:20 pm -
2 stops44h 50m
Deal found 10/15![Emirates logo]()
$3,026
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:55 pm -
2 stops28h 37m
Thu 11/59:50 am -
3 stops17h 15m
Deal found 10/16![Multiple Airlines logo]()
$1,971
Last-minute flights from Italy to Des MoinesDiscover last-minute flight deals from Italy to Des Moines. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Italy to Des Moines. Data last updated October 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:20 pm -
1 stop17h 39m
Thu 11/56:00 am -
1 stop19h 05m
Deal found 10/16![American Airlines logo]()
$1,049
This Iberia deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:20 am -
2 stops19h 36m
Thu 11/56:00 am -
2 stops20h 30m
Deal found 10/16![Multiple Airlines logo]()
$1,157
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:45 am -
2 stops16h 31m
Thu 11/59:50 am -
2 stops14h 40m
Deal found 10/16![United Airlines logo]()
$1,341
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:20 pm -
1 stop16h 27m
Sat 11/77:23 pm -
2 stops29h 42m
Deal found 10/18![American Airlines logo]()
$989
This Air Canada deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:05 pm -
2 stops28h 27m
Sat 11/79:55 am -
3 stops17h 10m
Deal found 10/18![Multiple Airlines logo]()
$1,355
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:00 pm -
2 stops17h 33m
Sun 11/85:50 pm -
2 stops16h 35m
Deal found 10/19![Delta logo]()
$802
This lol.travel deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:40 pm -
2 stops15h 19m
Sun 11/86:45 pm -
1 stop11h 30m
Deal found 10/19![Lufthansa logo]()
$948
This Expedia deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:40 pm -
2 stops15h 19m
Sun 11/86:05 am -
3 stops21h 00m
Deal found 10/19![Multiple Airlines logo]()
$1,034
One-way flights from Italy to Des MoinesSearch for one-way flight options from Italy to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from Italy to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:05 am -
3 stops38h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$795
This Turkish Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:55 am -
2 stops36h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$883
This Thrive Travel deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Thrive Travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:50 am -
1 stop19h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![British Airways logo]()
$900
This Thrive Travel deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Thrive Travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:00 am -
2 stops19h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![British Airways logo]()
$1,046
This Thrive Travel deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Thrive Travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:45 am -
1 stop19h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Lufthansa logo]()
$1,093
Find flight deals from Italy to Des Moines
Keep the following information in mind while searching for Italy to Des Moines flight deals. Data was last updated October 19, 2026.
Round-trip from | $898 (American Airlines) |
|---|---|
One-way from | $795 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Italy to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Italy to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 10/29
6:05 am-2:14 pm
3 stops38h 09m
Des Moines
Wed 12/31
12:00 am-7:00 am
Nonstop0h 00m
$795
MilanDes Moines
MXP Milan Malpensa - DSM Des Moines
MXPDSM
Milan Malpensa
Wed 11/4
12:00 pm-10:33 pm
2 stops17h 33m
Des Moines
Sun 11/8
5:50 pm-5:25 pm
2 stops16h 35m
$802
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Wed 10/28
6:55 am-1:20 pm
2 stops36h 25m
Des Moines
Wed 12/31
12:00 am-7:00 am
Nonstop0h 00m
$883
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 2/18
7:30 am-11:56 pm
2 stops23h 26m
Des Moines
Sun 2/21
3:55 pm-2:30 pm
2 stops15h 35m
$898
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 10/29
10:50 am-12:14 am
1 stop19h 24m
Des Moines
Wed 12/31
12:00 am-7:00 am
Nonstop0h 00m
$900
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 2/18
9:55 am-8:40 pm
2 stops17h 45m
Des Moines
Sun 2/21
8:00 am-7:55 am
2 stops16h 55m
$904
MilanDes Moines
MXP Milan Malpensa - DSM Des Moines
MXPDSM
Milan Malpensa
Tue 11/3
1:20 pm-10:47 pm
1 stop16h 27m
Des Moines
Sat 11/7
7:23 pm-8:05 am
2 stops29h 42m
$989
MilanDes Moines
MXP Milan Malpensa - DSM Des Moines
MXPDSM
Milan Malpensa
Wed 11/4
3:15 pm-10:59 pm
1 stop14h 44m
Des Moines
Sun 11/8
6:45 pm-1:15 pm
1 stop11h 30m
$1,016
MilanDes Moines
MXP Milan Malpensa - DSM Des Moines
MXPDSM
Milan Malpensa
Wed 11/4
2:40 pm-10:59 pm
2 stops15h 19m
Des Moines
Sun 11/8
6:05 am-10:05 am
3 stops21h 00m
$1,034
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Wed 10/28
11:00 am-12:14 am
2 stops19h 14m
Des Moines
Wed 12/31
12:00 am-7:00 am
Nonstop0h 00m
$1,046
Showing 1-10 of 16 resultsSorted by cheapest first
Best time to book a flight from Italy to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Italy with our price prediction graph.
MXP-DSM
FCO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Italy to Des Moines
IT0-DSM
MXP-DSM
FCO-DSM
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Italy to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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