$535+ Cheap flights from Italy to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — DSM
Sep 29 — Oct 61
Round-trip
1 adult, Economy
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Find cheap flights from Italy to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Italy to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Italy to Des MoinesExplore the most affordable flight options available from Italy to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 30, 2026.
Explore the most affordable flight options available from Italy to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 30, 2026.
This Expedia deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:45 pm -
1 stop13h 26m
Sat 9/194:10 pm -
1 stop32h 25m
Deal found 8/30![KLM logo]()
$813
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:30 am -
2 stops21h 30m
Mon 10/1911:27 am -
1 stop13h 08m
Deal found 8/28![Delta logo]()
$817
This lol.travel deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:20 am -
2 stops19h 01m
Sat 12/51:58 pm -
2 stops18h 07m
Deal found 8/28![British Airways logo]()
$861
This Iberia deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:35 am -
2 stops18h 46m
Sun 9/277:05 am -
1 stop19h 05m
Deal found 8/27![Iberia logo]()
$902
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:10 pm -
2 stops17h 31m
Sun 9/277:58 pm -
2 stops16h 22m
Deal found 8/30![American Airlines logo]()
$906
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:30 am -
2 stops17h 18m
Sun 9/272:34 pm -
1 stop15h 06m
Deal found 8/30![Delta logo]()
$912
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:35 am -
2 stops17h 11m
Sat 12/511:35 am -
1 stop13h 40m
Deal found 8/28![Delta logo]()
$918
This KLM deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:00 am -
1 stop15h 19m
Sat 12/511:35 am -
1 stop16h 45m
Deal found 8/28![KLM logo]()
$926
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:30 am -
2 stops14h 36m
Sat 9/195:35 pm -
1 stop34h 25m
Deal found 8/30![Delta logo]()
$936
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:10 am -
2 stops22h 05m
Sat 12/58:00 am -
3 stops16h 55m
Deal found 8/28![United Airlines logo]()
$1,026
Best flights from Italy to Des MoinesDiscover carefully curated flight deals from Italy to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 30, 2026.
Discover carefully curated flight deals from Italy to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 30, 2026.
This Expedia deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:45 pm -
1 stop13h 26m
Sat 9/194:10 pm -
1 stop32h 25m
Deal found 8/30![KLM logo]()
$813
This lol.travel deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:20 am -
2 stops19h 01m
Sat 12/51:58 pm -
2 stops18h 07m
Deal found 8/28![British Airways logo]()
$861
This Iberia deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:35 am -
2 stops18h 46m
Sun 9/277:05 am -
1 stop19h 05m
Deal found 8/27![Iberia logo]()
$902
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/187:30 am -
2 stops21h 53m
Sun 2/212:01 pm -
2 stops17h 29m
Deal found 8/29![American Airlines logo]()
$908
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:30 am -
2 stops17h 18m
Sun 9/272:34 pm -
1 stop15h 06m
Deal found 8/30![Delta logo]()
$912
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:35 am -
2 stops17h 11m
Sat 12/511:35 am -
1 stop13h 40m
Deal found 8/28![Delta logo]()
$918
This KLM deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:00 am -
1 stop15h 19m
Sat 12/511:35 am -
1 stop16h 45m
Deal found 8/28![KLM logo]()
$926
Last-minute flights from Italy to Des MoinesDiscover last-minute flight deals from Italy to Des Moines. Data last updated August 30, 2026 and is based on user searches.
Discover last-minute flight deals from Italy to Des Moines. Data last updated August 30, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:45 pm -
1 stop13h 26m
Sat 9/194:10 pm -
1 stop32h 25m
Deal found 8/30![KLM logo]()
$813
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:30 am -
2 stops14h 36m
Sat 9/195:35 pm -
1 stop34h 25m
Deal found 8/30![Delta logo]()
$936
This lol.travel deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:30 am -
2 stops32h 09m
Sat 9/195:57 pm -
2 stops33h 28m
Deal found 8/30![Aer Lingus logo]()
$1,039
This lol.travel deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:20 am -
2 stops19h 01m
Sat 12/51:58 pm -
2 stops18h 07m
Deal found 8/28![British Airways logo]()
$861
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:35 am -
2 stops17h 11m
Sat 12/511:35 am -
1 stop13h 40m
Deal found 8/28![Delta logo]()
$918
This KLM deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:00 am -
1 stop15h 19m
Sat 12/511:35 am -
1 stop16h 45m
Deal found 8/28![KLM logo]()
$926
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:10 am -
2 stops22h 05m
Sat 12/58:00 am -
3 stops16h 55m
Deal found 8/28![United Airlines logo]()
$1,026
This Iberia deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:35 am -
2 stops18h 46m
Sun 9/277:05 am -
1 stop19h 05m
Deal found 8/27![Iberia logo]()
$902
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:10 pm -
2 stops17h 31m
Sun 9/277:58 pm -
2 stops16h 22m
Deal found 8/30![American Airlines logo]()
$906
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:30 am -
2 stops17h 18m
Sun 9/272:34 pm -
1 stop15h 06m
Deal found 8/30![Delta logo]()
$912
One-way flights from Italy to Des MoinesSearch for one-way flight options from Italy to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 30, 2026.
Search for one-way flight options from Italy to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
2 stops22h 10m
Deal found 8/28![Multiple Airlines logo]()
$535
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:30 pm -
1 stop15h 03m
Deal found 8/28![Delta logo]()
$591
Find flight deals from Italy to Des Moines
Keep the following information in mind while searching for Italy to Des Moines flight deals. Data was last updated August 30, 2026.
Round-trip from | $813 (Expedia) |
|---|---|
One-way from | $535 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Italy to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 30, 2026.
Use the filters below to find and compare flights from Italy to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Tue 9/15
2:45 pm-9:11 pm
1 stop13h 26m
Des Moines
Sat 9/19
4:10 pm-7:35 am
1 stop32h 25m
$813
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 9/24
7:20 am-7:21 pm
2 stops19h 01m
Des Moines
Sat 12/5
1:58 pm-3:05 pm
2 stops18h 07m
$861
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Fri 9/25
7:35 am-7:21 pm
2 stops18h 46m
Des Moines
Sun 9/27
7:05 am-9:10 am
1 stop19h 05m
$902
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 2/18
7:30 am-10:23 pm
2 stops21h 53m
Des Moines
Sun 2/21
2:01 pm-2:30 pm
2 stops17h 29m
$908
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Fri 9/25
6:30 am-4:48 pm
2 stops17h 18m
Des Moines
Sun 9/27
2:34 pm-12:40 pm
1 stop15h 06m
$912
Quickest round-trip
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 9/24
10:35 am-8:46 pm
2 stops17h 11m
Des Moines
Sat 12/5
11:35 am-8:15 am
1 stop13h 40m
$918
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 9/24
9:00 am-5:19 pm
1 stop15h 19m
Des Moines
Sat 12/5
11:35 am-11:20 am
1 stop16h 45m
$926
Cheapest one-way
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 10/29
6:40 am-10:50 pm
2 stops22h 10m
$535
Quickest one-way
RomeDes Moines
FCO Rome Fiumicino - DSM Des Moines
FCODSM
Rome Fiumicino
Thu 10/29
1:30 pm-10:33 pm
1 stop15h 03m
$591
Sorted by cheapest first
Best time to book a flight from Italy to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Italy with our price prediction graph.
FCO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Italy to Des Moines
IT0-DSM
FCO-DSM
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Italy to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
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