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Des Moines

$489+ Cheap flights from Italy to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — DSM
Jun 3 — Jun 101
Wed 6/3
Wed 6/10
1 adult, Economy
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Cheap flight deals from Italy to Des Moines

One-way flights from Italy to Des Moines
Search for one-way flight options from Italy to Des Moines. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.

This British Airways deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:15 am
FCO
-
DSM
2 stops19h 02m
Multiple Airlines
Deal found 5/3$489
This Priceline deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:45 am
FCO
-
DSM
2 stops21h 43m
British Airways
Deal found 5/1$493
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:45 am
FCO
-
DSM
2 stops18h 26m
American Airlines
Deal found 5/1$550
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:15 pm
FCO
-
DSM
3 stops33h 21m
Multiple Airlines
Deal found 5/2$573
This Ovago deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:05 am
FCO
-
DSM
1 stop16h 06m
British Airways
Deal found 4/30$648
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:55 am
FCO
-
DSM
3 stops55h 39m
Multiple Airlines
Deal found 5/1$666

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Italy to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest one-way

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 10/10

7:15 am-7:17 pm

2 stops19h 02m

$489

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 9/26

8:45 am-11:28 pm

2 stops21h 43m

$493

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 10/10

8:45 am-8:11 pm

2 stops18h 26m

$551

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 5/28

12:15 pm-2:00 pm

2 stops32h 45m

$621
Quickest one-way

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 10/10

11:05 am-8:11 pm

1 stop16h 06m

$648

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/3

Sorted by cheapest first

Best time to book a flight from Italy to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Italy to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Italy?

    For a flight from Italy to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • What are the cheapest airlines to fly from Italy to Des Moines one-way?

    The cheapest airlines for a one-way flight from Italy to Des Moines are American Airlines ($483), Iberia ($594), and Aer Lingus ($606).

  • Can I find deals for flights from Italy to Des Moines that include hotel bookings?

    Yes. In addition to deals on Italy to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to Des Moines.

  • Can I find deals for business class flights from Italy to Des Moines?

    Yes. Cheapflights offers flight deals from Italy to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

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