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Des Moines

$459+ Cheap flights from Italy to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
NAP — DSM
Aug 4 — Aug 111
Tue 8/4
Tue 8/11
1 adult, Economy
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Cheap flight deals from Italy to Des Moines

Cheapest flights from Italy to Des Moines
Explore the most affordable flight options available from Italy to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 5, 2026.

This Booking.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:00 am
FCO
-
DSM
1 stop15h 33m
British Airways
Mon 7/206:33 pm
DSM
-
FCO
2 stops18h 32m
British Airways
Deal found 7/1$1,030
This Iberia deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:35 am
FCO
-
DSM
2 stops19h 38m
Iberia
Wed 7/221:35 pm
DSM
-
FCO
1 stop12h 35m
Iberia
Deal found 7/3$1,038
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:35 am
FCO
-
DSM
2 stops17h 58m
American Airlines
Mon 7/201:35 pm
DSM
-
FCO
2 stops17h 20m
American Airlines
Deal found 7/1$1,040
This Travelis deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelis is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/189:45 am
FCO
-
DSM
1 stop19h 44m
KLM
Wed 7/2210:25 am
DSM
-
FCO
1 stop17h 35m
KLM
Deal found 7/3$1,049
This Iberia deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:35 am
FCO
-
DSM
2 stops17h 28m
Iberia
Fri 7/249:02 am
DSM
-
FCO
1 stop17h 08m
Iberia
Deal found 7/5$1,223
This Air Canada deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1811:30 am
FCO
-
DSM
3 stops18h 30m
Multiple Airlines
Wed 7/228:00 am
DSM
-
FCO
2 stops18h 15m
Multiple Airlines
Deal found 7/3$1,329
This Air Canada deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1811:30 am
FCO
-
DSM
3 stops18h 30m
Air Canada
Wed 7/228:00 am
DSM
-
FCO
3 stops18h 15m
Air Canada
Deal found 7/3$1,337
This Air Canada deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2011:30 am
FCO
-
DSM
3 stops18h 26m
Multiple Airlines
Fri 7/2411:23 am
DSM
-
FCO
2 stops17h 22m
Multiple Airlines
Deal found 7/5$1,576

Find flight deals from Italy to Des Moines

Keep the following information in mind while searching for Italy to Des Moines flight deals. Data was last updated July 5, 2026.

Round-trip from

$1,030
(Booking.com)

One-way from

$459
(Kiwi.com)
From Italy to Des Moines
Search Deals
One-way flight from Italy to Des Moines
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Italy to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 5, 2026.
Use the filters below to find and compare flights from Italy to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 7/16

10:00 am-6:33 pm

1 stop15h 33m

Des Moines

Mon 7/20

6:33 pm-8:05 pm

2 stops18h 32m

$1,030
Quickest round-trip

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 7/18

7:35 am-8:13 pm

2 stops19h 38m

Des Moines

Wed 7/22

1:35 pm-9:10 am

1 stop12h 35m

$1,038

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 7/16

7:35 am-6:33 pm

2 stops17h 58m

Des Moines

Mon 7/20

1:35 pm-1:55 pm

2 stops17h 20m

$1,040

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Mon 7/20

7:35 am-6:03 pm

2 stops17h 28m

Des Moines

Fri 7/24

9:02 am-9:10 am

1 stop17h 08m

$1,223

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 7/18

11:30 am-11:00 pm

3 stops18h 30m

Des Moines

Wed 7/22

8:00 am-9:15 am

2 stops18h 15m

$1,329

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Sat 7/18

11:30 am-11:00 pm

3 stops18h 30m

Des Moines

Wed 7/22

8:00 am-9:15 am

3 stops18h 15m

$1,337

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Mon 7/20

11:30 am-10:56 pm

3 stops18h 26m

Des Moines

Fri 7/24

11:23 am-11:45 am

2 stops17h 22m

$1,576

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 7/16

11:30 am-10:56 pm

2 stops18h 26m

Des Moines

Mon 7/20

11:23 am-12:30 pm

3 stops18h 07m

$1,757
Cheapest one-way

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Fri 9/25

5:45 am-8:46 pm

3 stops46h 01m

$459

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Mon 9/21

8:25 pm-5:26 pm

2 stops28h 01m

$474

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 18 resultsSorted by cheapest first
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Best time to book a flight from Italy to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Italy with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Italy to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Italy?

    For a flight from Italy to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Italy to Des Moines?

    Departing from Italy to Des Moines will take you 15h 33m. The distance between Italy and Des Moines is about 5054 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Italy to Des Moines one-way?

    The cheapest airlines for a one-way flight from Italy to Des Moines are American Airlines ($483), Aer Lingus ($606), and British Airways ($691).

  • Can I find deals for flights from Italy to Des Moines that include hotel bookings?

    Yes. In addition to deals on Italy to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Italy to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to Des Moines.

  • Can I find deals for business class flights from Italy to Des Moines?

    Yes. Cheapflights offers flight deals from Italy to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

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