$516+ Cheap flights from Madrid, Spain (MAD) to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — DSM
Nov 29 — Dec 61
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Madrid to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Madrid to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Madrid to Des MoinesExplore the most affordable flight options available from Madrid to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Madrid to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Trip.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:20 am -
2 stops35h 01m
Mon 11/167:00 am -
2 stops24h 05m
Deal found 10/27![Multiple Airlines logo]()
$738
This Rumbo deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:20 am -
2 stops20h 15m
Thu 12/310:30 am -
2 stops37h 50m
Deal found 10/29![Virgin Atlantic logo]()
$1,003
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:05 am -
2 stops20h 10m
Tue 11/175:29 pm -
2 stops18h 41m
Deal found 10/28![Delta logo]()
$1,004
This Rumbo deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:20 am -
2 stops20h 15m
Tue 12/12:58 pm -
2 stops33h 22m
Deal found 10/27![Virgin Atlantic logo]()
$1,005
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:05 am -
2 stops20h 10m
Mon 11/1611:36 am -
1 stop15h 09m
Deal found 10/27![Delta logo]()
$1,012
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:20 pm -
1 stop29h 24m
Tue 12/111:38 am -
1 stop15h 07m
Deal found 10/27![Delta logo]()
$1,017
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:00 am -
2 stops17h 55m
Sun 11/156:05 am -
2 stops18h 40m
Deal found 10/25![United Airlines logo]()
$1,019
Best flights from Madrid to Des MoinesDiscover carefully curated flight deals from Madrid to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Madrid to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1310:50 am -
2 stops30h 09m
Wed 1/2011:46 am -
2 stops20h 34m
Deal found 10/26![Delta logo]()
$953
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:20 pm -
2 stops16h 39m
Sun 11/158:00 am -
3 stops18h 30m
Deal found 10/28![United Airlines logo]()
$1,132
This KLM deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:00 am -
2 stops19h 59m
Sun 2/2111:04 am -
1 stop15h 41m
Deal found 10/29![KLM logo]()
$1,162
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:05 am -
2 stops20h 10m
Tue 11/175:29 pm -
2 stops18h 41m
Deal found 10/28![Delta logo]()
$1,004
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:05 am -
2 stops17h 44m
Tue 12/12:58 pm -
1 stop11h 47m
Deal found 10/27![Delta logo]()
$1,012
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:05 am -
2 stops21h 40m
Sun 2/2110:55 am -
2 stops17h 35m
Deal found 10/29![Delta logo]()
$1,159
Last-minute flights from Madrid to Des MoinesDiscover last-minute flight deals from Madrid to Des Moines. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Madrid to Des Moines. Data last updated October 30, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:00 am -
2 stops17h 55m
Sun 11/156:05 am -
2 stops18h 40m
Deal found 10/25![United Airlines logo]()
$1,019
This Trip.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:20 am -
2 stops35h 01m
Mon 11/167:00 am -
2 stops24h 05m
Deal found 10/27![Multiple Airlines logo]()
$738
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:05 am -
2 stops20h 10m
Mon 11/1611:36 am -
1 stop15h 09m
Deal found 10/27![Delta logo]()
$1,012
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:05 am -
2 stops20h 10m
Tue 11/175:29 pm -
2 stops18h 41m
Deal found 10/28![Delta logo]()
$1,004
This Rumbo deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:20 am -
2 stops20h 15m
Tue 12/12:58 pm -
2 stops33h 22m
Deal found 10/27![Virgin Atlantic logo]()
$1,005
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:20 pm -
1 stop29h 24m
Tue 12/111:38 am -
1 stop15h 07m
Deal found 10/27![Delta logo]()
$1,017
This Rumbo deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:20 am -
2 stops20h 15m
Thu 12/310:30 am -
2 stops37h 50m
Deal found 10/29![Virgin Atlantic logo]()
$1,003
One-way flights from Madrid to Des MoinesSearch for one-way flight options from Madrid to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Madrid to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:40 am -
3 stops38h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$516
Find flight deals from Madrid to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | eDreams 2 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $738 (Trip.com) |
One-way from | $516 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Madrid to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Madrid to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Thu 11/12
6:40 am-2:21 pm
3 stops38h 41m
Des Moines
Wed 12/31
12:00 am-7:00 am
Nonstop0h 00m
$516
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Wed 1/13
10:50 am-9:59 am
2 stops30h 09m
Des Moines
Wed 1/20
11:46 am-3:20 pm
2 stops20h 34m
$953
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Fri 11/13
6:05 am-7:15 pm
2 stops20h 10m
Des Moines
Tue 11/17
5:29 pm-7:10 pm
2 stops18h 41m
$1,004
Quickest round-trip
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Tue 11/24
6:05 am-4:49 pm
2 stops17h 44m
Des Moines
Tue 12/1
2:58 pm-9:45 am
1 stop11h 47m
$1,012
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Wed 11/11
1:20 pm-10:59 pm
2 stops16h 39m
Des Moines
Sun 11/15
8:00 am-9:30 am
3 stops18h 30m
$1,132
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Mon 12/21
6:05 am-8:45 pm
2 stops21h 40m
Des Moines
Sun 2/21
10:55 am-11:30 am
2 stops17h 35m
$1,159
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Mon 12/21
7:00 am-7:59 pm
2 stops19h 59m
Des Moines
Sun 2/21
11:04 am-9:45 am
1 stop15h 41m
$1,162
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Madrid-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Madrid-Des Moines flight deals on Cheapflights vs. eDreams 90-95% of the time. Price accuracy is based on data collected from Madrid-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Madrid-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Madrid to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Madrid with our price prediction graph.
MAD-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Madrid to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Madrid
Popular flights