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Panama City

$206+ Cheap flights from Myrtle Beach (MYR) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — PTY
Feb 4 — Feb 111
Wed 2/4
Wed 2/11
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Panama City

Cheapest flights from Myrtle Beach to Panama City
Explore the most affordable flight options available from Myrtle Beach to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 5, 2026.

This American Airlines deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:35 pmMYR - PTY
2 stops20h 45mAmerican Airlines
Wed 3/251:40 pmPTY - MYR
2 stops17h 51mAmerican Airlines
Deal found 1/3$441
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:35 pmMYR - PTY
2 stops20h 45mAmerican Airlines
Thu 3/261:40 pmPTY - MYR
2 stops19h 26mAmerican Airlines
Deal found 1/4$481
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:18 pmMYR - PTY
2 stops22h 02mAmerican Airlines
Mon 3/163:10 pmPTY - MYR
2 stops19h 29mAmerican Airlines
Deal found 1/4$501
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:18 pmMYR - PTY
2 stops20h 22mAmerican Airlines
Tue 3/171:40 pmPTY - MYR
2 stops20h 59mAmerican Airlines
Deal found 1/4$551
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:18 pmMYR - PTY
2 stops22h 02mAmerican Airlines
Tue 3/173:10 pmPTY - MYR
2 stops20h 05mAmerican Airlines
Deal found 1/4$571
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:01 amMYR - PTY
2 stops9h 19mAmerican Airlines
Mon 3/163:10 pmPTY - MYR
2 stops24h 23mAmerican Airlines
Deal found 1/4$593
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:35 pmMYR - PTY
2 stops19h 05mAmerican Airlines
Sun 3/153:10 pmPTY - MYR
2 stops43h 11mAmerican Airlines
Deal found 1/4$597
This Gurufare deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:05 pmMYR - PTY
1 stop25h 57mAvianca
Tue 3/179:30 amPTY - MYR
1 stop25h 46mAvianca
Deal found 1/4$668
This Gurufare deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:05 pmMYR - PTY
1 stop25h 57mAvianca
Sun 3/1510:55 pmPTY - MYR
1 stop17h 10mAvianca
Deal found 1/4$687
This Delta deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/810:23 amMYR - PTY
1 stop27h 40mDelta
Tue 3/172:28 pmPTY - MYR
1 stop8h 38mDelta
Deal found 1/4$729
This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:58 amMYR - PTY
2 stops15h 42mMultiple Airlines
Tue 3/1712:03 pmPTY - MYR
1 stop26h 40mMultiple Airlines
Deal found 1/4$731
This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/109:09 amMYR - PTY
2 stops16h 51mMultiple Airlines
Tue 3/1712:03 pmPTY - MYR
1 stop26h 40mMultiple Airlines
Deal found 1/4$733

Find flight deals from Myrtle Beach to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 5, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$441
(American Airlines)

One-way from

$206
(American Airlines)
Provider with most accurate pricing for Myrtle Beach Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Panama City Tocumen Intl flights.
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From Myrtle Beach Intl to Panama City Tocumen Intl
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One-way flight from Myrtle Beach Intl to Panama City Tocumen Intl
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 5, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama City that are best for you.

Fly from

Myrtle Beach

Fly to

Panama City

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 3/10

6:35 pm-2:20 pm

2 stops20h 45m

Panama City Tocumen Intl

Wed 3/25

1:40 pm-8:31 am

2 stops17h 51m

$441

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:35 pm-2:20 pm

2 stops20h 45m

Panama City Tocumen Intl

Thu 3/26

1:40 pm-10:06 am

2 stops19h 26m

$481

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 3/9

5:18 pm-2:20 pm

2 stops22h 02m

Panama City Tocumen Intl

Mon 3/16

3:10 pm-11:39 am

2 stops19h 29m

$501

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 3/9

5:18 pm-12:40 pm

2 stops20h 22m

Panama City Tocumen Intl

Tue 3/17

1:40 pm-11:39 am

2 stops20h 59m

$551

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 3/8

5:18 pm-2:20 pm

2 stops22h 02m

Panama City Tocumen Intl

Tue 3/17

3:10 pm-12:15 pm

2 stops20h 05m

$571

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 3/10

6:01 am-2:20 pm

2 stops9h 19m

Panama City Tocumen Intl

Mon 3/16

3:10 pm-4:33 pm

2 stops24h 23m

$593

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 3/9

6:35 pm-12:40 pm

2 stops19h 05m

Panama City Tocumen Intl

Sun 3/15

3:10 pm-11:21 am

2 stops43h 11m

$597

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 3/10

12:57 pm-7:02 pm

1 stop31h 05m

Panama City Tocumen Intl

Tue 3/17

9:30 am-12:16 pm

1 stop25h 46m

$668

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 3/9

6:05 pm-7:02 pm

1 stop25h 57m

Panama City Tocumen Intl

Mon 3/16

9:30 am-5:05 pm

1 stop30h 35m

$668

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 3/9

6:05 pm-7:02 pm

1 stop25h 57m

Panama City Tocumen Intl

Sun 3/15

10:55 pm-5:05 pm

1 stop17h 10m

$687

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/3

Showing 1-10 of 16 results
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Compare providers for flights from Myrtle Beach to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Panama City

What is the cheapest month to book a flight from Myrtle Beach to Panama City?

Currently, July is the cheapest month in which you can book a flight from Myrtle Beach to Panama City (average of $230). Flying from Myrtle Beach to Panama City in April is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to Panama City?

    There are many flights that can get you from Myrtle Beach to Panama City in 20h 45m. Fly via American Airlines to get the fastest option. The distance between Myrtle Beach and Panama City is about 1700 mi.

  • What is the cheapest airline to fly from Myrtle Beach to Panama City round-trip?

    Cheapflights users have booked flights from Myrtle Beach to Panama City round-trip from $486.

  • Can I find deals for flights from Myrtle Beach to Panama City that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Panama City.

  • Can I find deals for business class flights from Myrtle Beach to Panama City?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Panama City?

    Currently, July is the cheapest month in which you can book a flight from Myrtle Beach to Panama City (average of $230). Flying from Myrtle Beach to Panama City in April is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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