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$258+ Cheap flights from Indianapolis (IND) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Indianapolis to Panama City Tocumen Intl are usually found in October or July, booked 67 days in advance, depart on a Tuesday or Monday and return on a Thursday

Cheap flight deals from Indianapolis to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$489
(American Airlines)

One-way from

$258
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$569
From Indianapolis to Panama City Tocumen Intl
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One-way flight from Indianapolis to Panama City Tocumen Intl
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Highest demand for flights based on searches. 6% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Indianapolis to Panama City

Cheapest flights from Indianapolis to Panama City
Explore the most affordable flight options available from Indianapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:00 amIND - PTY
1 stop7h 56mDelta
Thu 11/63:21 pmPTY - IND
1 stop9h 01mDelta
Deal found 9/10$489
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:00 amIND - PTY
2 stops13h 38mUnited Airlines
Thu 11/64:41 pmPTY - IND
2 stops18h 32mUnited Airlines
Deal found 9/10$494
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:00 amIND - PTY
1 stop7h 49mAmerican Airlines
Sat 11/82:49 pmPTY - IND
1 stop9h 07mAmerican Airlines
Deal found 9/10$509
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:22 pmIND - PTY
1 stop26h 16mUnited Airlines
Wed 11/128:55 amPTY - IND
1 stop14h 49mUnited Airlines
Deal found 9/10$519
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:12 pmIND - PTY
1 stop18h 37mAmerican Airlines
Wed 11/122:49 pmPTY - IND
1 stop9h 07mAmerican Airlines
Deal found 9/11$521
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:15 amIND - PTY
1 stop8h 35mUnited Airlines
Thu 10/307:55 amPTY - IND
1 stop14h 49mUnited Airlines
Deal found 9/11$529
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:51 pmIND - PTY
1 stop19h 05mDelta
Wed 10/292:21 pmPTY - IND
1 stop9h 01mDelta
Deal found 9/11$538
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:07 pmIND - PTY
1 stop19h 56mAmerican Airlines
Mon 11/32:49 pmPTY - IND
1 stop9h 07mAmerican Airlines
Deal found 9/11$541
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:59 pmIND - PTY
1 stop17h 57mDelta
Thu 10/302:21 pmPTY - IND
1 stop19h 12mDelta
Deal found 9/11$546
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:00 amIND - PTY
1 stop6h 56mDelta
Tue 10/282:21 pmPTY - IND
1 stop9h 01mDelta
Deal found 9/11$549

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama City that are best for you.

Fly from

Indianapolis

Fly to

Panama City

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/4

6:00 am-1:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Thu 11/6

3:21 pm-12:22 am

1 stop9h 01m

$489

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/4

6:00 am-7:38 pm

2 stops13h 38m

Panama City Tocumen Intl

Thu 11/6

4:41 pm-11:13 am

2 stops18h 32m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/4

4:12 pm-1:49 pm

2 stops21h 37m

Panama City Tocumen Intl

Fri 11/7

2:49 pm-9:47 am

2 stops18h 58m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/10

6:45 am-1:45 pm

1 stop8h 00m

Panama City Tocumen Intl

Thu 3/12

3:40 pm-9:21 am

2 stops16h 41m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/14

6:00 am-7:59 pm

1 stop13h 59m

Panama City Tocumen Intl

Mon 11/17

3:37 pm-12:26 am

1 stop8h 49m

$509

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/4

4:40 pm-1:49 pm

2 stops21h 09m

Panama City Tocumen Intl

Sat 11/8

2:49 pm-10:20 am

2 stops19h 31m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/14

5:44 pm-2:45 pm

2 stops21h 01m

Panama City Tocumen Intl

Mon 11/17

4:41 pm-10:53 am

1 stop18h 12m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 10/21

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

Tue 11/4

8:55 am-11:18 pm

2 stops14h 23m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/7

7:00 pm-1:49 pm

2 stops18h 49m

$258

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/7

6:45 am-7:38 pm

1 stop12h 53m

$272

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Indianapolis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama City

How far ahead should I book a flight from Indianapolis to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Indianapolis to Panama City. Price data was last updated on August 29, 2025.

Booking 67 days in advance of your planned departure date is, on average, the best time to get cheap flights from Indianapolis to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Indianapolis to Panama City?

Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama City (average of $478). Flying from Indianapolis to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PTY?

Find hourly flight availability from Indianapolis to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 8% on flights from Indianapolis to Panama City by exploring options for tickets in the afternoon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Indianapolis to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to Panama City?

    There are many flights that can get you from Indianapolis to Panama City in 7h 56m. Fly via Delta or United Airlines to get the fastest option. Indianapolis and Panama City are separated by a distance of 2158 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $463. Additional round-trip tickets that might be worth considering are offered by United Airlines and Delta, with the lowest prices starting at $469 and $477, respectively. American Airlines is currently priced 23% below the average price you’ll pay for this route.

  • Can I find deals for flights from Indianapolis to Panama City that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama City.

  • Can I find deals for business class flights from Indianapolis to Panama City?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama City (average of $478). Flying from Indianapolis to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Indianapolis to Panama City

Discover the top 3 airlines that operate flights from Indianapolis to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$655FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$600FlexibilityNo cancel feeOn-time69%
DeltaCheapest$477Average$557FlexibilityNo cancel feeOn-timeN/A

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