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$232+ Cheap flights from Indianapolis (IND) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheapflights Tip: The best prices from Indianapolis to Panama City Tocumen Intl are usually found in September or July, booked 68 days in advance, depart on a Tuesday or Monday and return on a Thursday

Cheap flight deals from Indianapolis to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$490
(Delta)

One-way from

$232
(Delta)

Popular in

December

Cheapest in

September

Average price

$640
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
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From Indianapolis to Panama City Tocumen Intl
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One-way flight from Indianapolis to Panama City Tocumen Intl
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Highest demand for flights based on searches. 9% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Indianapolis to Panama City

Cheapest flights from Indianapolis to Panama City
Explore the most affordable flight options available from Indianapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:00 amIND - PTY
1 stop12h 38mUnited Airlines
Thu 12/188:55 amPTY - IND
1 stop14h 49mUnited Airlines
Deal found 10/27$510
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:45 amIND - PTY
1 stop8h 00mUnited Airlines
Tue 12/210:00 amPTY - IND
1 stop10h 22mUnited Airlines
Deal found 10/28$530
This Avianca Connect deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/279:03 amIND - PTY
2 stops15h 57mMultiple Airlines
Wed 12/32:55 amPTY - IND
2 stops18h 40mMultiple Airlines
Deal found 10/26$538
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amIND - PTY
1 stop7h 43mAmerican Airlines
Tue 12/22:43 pmPTY - IND
1 stop9h 13mAmerican Airlines
Deal found 10/29$550
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:14 pmIND - PTY
1 stop26h 24mUnited Airlines
Sat 12/1311:55 pmPTY - IND
1 stop9h 20mUnited Airlines
Deal found 10/29$560
This Avianca Connect deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:00 amIND - PTY
2 stops18h 00mMultiple Airlines
Mon 12/12:55 amPTY - IND
2 stops20h 24mMultiple Airlines
Deal found 10/28$582
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:02 pmIND - PTY
2 stops18h 41mAmerican Airlines
Tue 12/22:43 pmPTY - IND
2 stops21h 28mAmerican Airlines
Deal found 10/27$584

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama City that are best for you.

Fly from

Indianapolis

Fly to

Panama City

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/10

7:10 am-12:55 pm

1 stop6h 45m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-9:00 am

1 stop17h 40m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/10

6:45 am-4:07 pm

1 stop10h 22m

Panama City Tocumen Intl

Thu 3/12

3:41 pm-10:59 am

2 stops18h 18m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 3/4

6:45 am-2:45 pm

1 stop8h 00m

Panama City Tocumen Intl

Sun 3/8

9:30 am-8:49 pm

1 stop10h 19m

$510

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 2/24

7:10 am-2:02 pm

1 stop6h 52m

Panama City Tocumen Intl

Sun 3/1

3:27 pm-9:00 am

1 stop17h 33m

$510

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 2/25

9:00 am-5:07 pm

1 stop8h 07m

Panama City Tocumen Intl

Sun 3/1

10:00 am-8:50 pm

1 stop10h 50m

$510

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/25

3:39 pm-1:43 pm

2 stops22h 04m

$232

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/25

7:00 am-2:12 pm

1 stop7h 12m

$232

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 4/24

6:36 am-12:15 pm

1 stop6h 39m

$232

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 1/15

9:31 pm-3:38 pm

2 stops18h 07m

$238

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/7

6:00 am-1:49 pm

1 stop7h 49m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 12 results
1
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Compare providers for flights from Indianapolis to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Indianapolis-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Indianapolis-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama City

How far ahead should I book a flight from Indianapolis to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Indianapolis to Panama City. Price data was last updated on October 24, 2025.

Booking 67 days in advance of your planned departure date is, on average, the best time to get cheap flights from Indianapolis to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Indianapolis to Panama City?

Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama City (average of $382). Flying from Indianapolis to Panama City in August is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PTY?

Find hourly flight availability from Indianapolis to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 7% on flights from Indianapolis to Panama City by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from Indianapolis to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 29, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Indianapolis to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to Panama City?

    There are many flights that can get you from Indianapolis to Panama City in 6h 45m. Fly via Delta or United Airlines to get the fastest option. Indianapolis and Panama City are separated by a distance of 2158 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $463. Additional round-trip tickets that might be worth considering are offered by United Airlines and Delta, with the lowest prices starting at $469 and $473, respectively. American Airlines is currently priced 23% below the average price you’ll pay for this route.

  • Can I find deals for flights from Indianapolis to Panama City that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama City.

  • Can I find deals for business class flights from Indianapolis to Panama City?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama City (average of $382). Flying from Indianapolis to Panama City in August is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Indianapolis to Panama City

Discover the top 3 airlines that operate flights from Indianapolis to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$673FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$605FlexibilityNo cancel feeOn-time69%
DeltaCheapest$473Average$617FlexibilityNo cancel feeOn-timeN/A

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