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Panama City

$252+ Cheap flights from Indianapolis (IND) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Jan 13 — Jan 201
Tue 1/13
Tue 1/20
1 adult, Economy
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Find cheap flights from Indianapolis to Panama City with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Indianapolis to Panama City Tocumen Intl are usually found in September or July, booked 68 days in advance, depart on a Tuesday or Monday and return on a Thursday

Cheap flight deals from Indianapolis to Panama City

Cheapest flights from Indianapolis to Panama City
Explore the most affordable flight options available from Indianapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:52 amIND - PTY
2 stops26h 01mAmerican Airlines
Wed 12/312:53 pmPTY - IND
1 stop9h 06mAmerican Airlines
Deal found 12/14$616
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amIND - PTY
1 stop7h 53mAmerican Airlines
Thu 1/82:27 pmPTY - IND
2 stops20h 11mAmerican Airlines
Deal found 12/13$624
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:20 amIND - PTY
1 stop13h 18mUnited Airlines
Sun 8/97:55 amPTY - IND
1 stop10h 52mUnited Airlines
Deal found 12/13$756
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 pmIND - PTY
2 stops19h 53mAmerican Airlines
Sun 8/93:20 pmPTY - IND
2 stops21h 25mAmerican Airlines
Deal found 12/13$779
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:32 pmIND - PTY
2 stops20h 21mAmerican Airlines
Mon 1/54:55 pmPTY - IND
2 stops19h 42mAmerican Airlines
Deal found 12/14$890
This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:00 amIND - PTY
1 stop11h 35mCopa Airlines
Mon 1/510:29 pmPTY - IND
1 stop11h 59mCopa Airlines
Deal found 12/13$977
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:45 pmIND - PTY
2 stops21h 22mUnited Airlines
Mon 1/54:41 pmPTY - IND
1 stop18h 07mUnited Airlines
Deal found 12/13$1,056
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:20 amIND - PTY
1 stop13h 18mUnited Airlines
Sun 1/44:41 pmPTY - IND
2 stops18h 32mUnited Airlines
Deal found 12/12$1,353
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 pmIND - PTY
2 stops19h 53mAmerican Airlines
Sun 1/44:55 pmPTY - IND
2 stops20h 23mAmerican Airlines
Deal found 12/12$1,356

Find flight deals from Indianapolis to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 14, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$490
(American Airlines)

One-way from

$252
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$1,308
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
Search Deals
From Indianapolis to Panama City Tocumen Intl
Search Deals
One-way flight from Indianapolis to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($164 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($61 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama City that are best for you.

Fly from

Indianapolis

Fly to

Panama City

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 4/22

11:47 am-6:37 pm

1 stop7h 50m

Panama City Tocumen Intl

Mon 4/27

10:55 pm-1:00 pm

2 stops13h 05m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 3/30

8:04 pm-2:22 pm

2 stops19h 18m

Panama City Tocumen Intl

Fri 4/3

3:13 pm-10:45 am

1 stop18h 32m

$506

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 4/20

9:20 am-4:12 pm

1 stop7h 52m

Panama City Tocumen Intl

Sat 4/25

10:00 am-9:26 pm

1 stop10h 26m

$510

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 4/21

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

Sun 4/26

10:55 pm-4:52 pm

2 stops16h 57m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/21

8:10 pm-1:45 pm

2 stops18h 35m

Panama City Tocumen Intl

Thu 4/2

10:55 pm-4:52 pm

2 stops16h 57m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 2/24

5:57 pm-1:50 pm

2 stops19h 53m

Panama City Tocumen Intl

Sun 3/1

4:05 pm-10:12 am

1 stop18h 07m

$519

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 3/12

6:00 am-6:38 pm

2 stops13h 38m

Panama City Tocumen Intl

Mon 3/16

3:41 pm-10:46 am

1 stop18h 05m

$519

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/21

5:05 pm-4:07 pm

1 stop24h 02m

Panama City Tocumen Intl

Wed 4/1

7:55 am-9:26 pm

1 stop12h 31m

$520

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/21

7:23 pm-2:22 pm

1 stop19h 59m

Panama City Tocumen Intl

Thu 4/2

3:13 pm-10:08 am

1 stop17h 55m

$522

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 1/4

7:45 pm-2:45 pm

2 stops19h 00m

$252

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/12

Showing 1-10 of 14 results
1
2

Compare providers for flights from Indianapolis to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Indianapolis-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Indianapolis-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Indianapolis-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Indianapolis-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama City

How far ahead should I book a flight from Indianapolis to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Indianapolis to Panama City. Price data was last updated on December 12, 2025.

Booking 67 days in advance of your planned departure date is, on average, the best time to get cheap flights from Indianapolis to Panama City. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Indianapolis to Panama City?

Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama City (average of $382). Flying from Indianapolis to Panama City in December is currently the most expensive (average of $556). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PTY?

Find hourly flight availability from Indianapolis to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 14, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 7% on flights from Indianapolis to Panama City by exploring options for tickets in the afternoon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 14, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Indianapolis to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,052 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Indianapolis to Panama City?

    There are many flights that can get you from Indianapolis to Panama City in 7h 50m. Fly via United Airlines or American Airlines to get the fastest option. Indianapolis and Panama City are separated by a distance of 2158 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Indianapolis to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $469. Additional round-trip tickets that might be worth considering are offered by United Airlines and Delta, with the lowest prices starting at $469 and $473, respectively. American Airlines is currently priced 27% below the average price you’ll pay for this route.

  • Can I find deals for flights from Indianapolis to Panama City that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama City.

  • Can I find deals for business class flights from Indianapolis to Panama City?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Indianapolis to Panama City (average of $382). Flying from Indianapolis to Panama City in December is currently the most expensive (average of $556). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Indianapolis to Panama City

Discover the top 3 airlines that operate flights from Indianapolis to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$469Average$673FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$619FlexibilityNo cancel feeOn-time69%
DeltaCheapest$473Average$640FlexibilityNo cancel feeOn-timeN/A

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