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$181+ Cheap flights from Indianapolis (IND) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Indianapolis to Panama

Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated July 3, 2025.

Round-trip from

$494
(United Airlines)

One-way from

$181
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$529
From Indianapolis to Panama
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One-way flight from Indianapolis to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($43 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Indianapolis to Panama

Cheapest flights from Indianapolis to Panama
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amIND - PTY
1 stop7h 47mDelta
Wed 10/292:12 pmPTY - IND
1 stop8h 45mDelta
Deal found 7/2$396
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amIND - PTY
2 stops9h 00mAmerican Airlines
Wed 10/293:19 pmPTY - IND
2 stops19h 49mAmerican Airlines
Deal found 7/2$401
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:00 amIND - PTY
1 stop8h 55mUnited Airlines
Mon 11/34:41 pmPTY - IND
1 stop18h 12mUnited Airlines
Deal found 7/2$461
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/155:05 amIND - PTY
3 stops20h 40mMultiple Airlines
Fri 8/2210:05 pmPTY - IND
3 stops34h 07mMultiple Airlines
Deal found 7/1$501

Cheapflights Fare Finder

Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Indianapolis

Fly to

Panama

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 9/2

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

Mon 9/15

3:30 pm-1:17 pm

2 stops20h 47m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 8/15

5:05 am-12:45 am

3 stops20h 40m

Panama City Tocumen Intl

Fri 8/22

10:05 pm-9:12 am

3 stops34h 07m

$501

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 8/15

7:17 pm-2:30 pm

2 stops20h 13m

Panama City Tocumen Intl

Fri 8/22

3:30 pm-11:44 am

2 stops19h 14m

$534

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 9/24

7:30 pm-9:10 pm

2 stops26h 40m

$181

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 9/24

6:19 am-12:55 pm

1 stop7h 36m

$232

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Indianapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Panama

What is the cheapest month to book a flight from Indianapolis to Panama?

Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to PA?

Find hourly flight availability from Indianapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

When flying from Indianapolis to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Indianapolis to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,845 reviews

Entertainment

7.0

Overall

7.4

Comfort

7.3

Crew

8.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,845 reviews
United Airlines
7.4
Good
8,845 reviews

Entertainment

7.0

Overall

7.4

Comfort

7.3

Crew

8.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,845 reviews

Entertainment

7.0

Overall

7.4

Comfort

7.3

Crew

8.1

Boarding

7.7

Food

6.6

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to Panama?

    For a flight from Indianapolis to Panama, you will be flying from Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • Can I find deals for flights from Indianapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Indianapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Panama.

  • Can I find deals for business class flights from Indianapolis to Panama?

    Yes. Cheapflights offers flight deals from Indianapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to Panama?

    Currently, October is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $478). Flying from Indianapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indianapolis to Panama

Discover the top 3 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$449Average$562FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$462Average$644FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$468Average$595FlexibilityNo cancel feeOn-time69%

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