$246+ Cheap flights from Indianapolis (IND) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Aug 24 — Aug 311
Round-trip
1 adult, Economy
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Best
Last-minute
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Cheapest flights from Indianapolis to PanamaExplore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.
Explore the most affordable flight options available from Indianapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:05 am
IND
- PTY
1 stop11h 57m
United Airlines
Tue 11/178:55 am
PTY
- IND
3 stops14h 46m
United Airlines
Deal found 7/23![United Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:25 am
IND
- PTY
1 stop10h 12m
United Airlines
Mon 9/213:30 pm
PTY
- IND
1 stop18h 18m
United Airlines
Deal found 7/24![United Airlines logo]()
$567
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:57 pm
IND
- PTY
2 stops18h 19m
American Airlines
Tue 9/291:16 pm
PTY
- IND
2 stops20h 10m
American Airlines
Deal found 7/25![American Airlines logo]()
$581
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am
IND
- PTY
1 stop7h 58m
Delta
Sun 10/42:23 pm
PTY
- IND
1 stop9h 09m
Delta
Deal found 7/25![Delta logo]()
$591
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:31 pm
IND
- PTY
2 stops19h 43m
United Airlines
Fri 9/1810:00 am
PTY
- IND
1 stop9h 04m
United Airlines
Deal found 7/23![United Airlines logo]()
$595
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:00 am
IND
- PTY
1 stop7h 16m
American Airlines
Fri 9/181:16 pm
PTY
- IND
1 stop9h 01m
American Airlines
Deal found 7/20![American Airlines logo]()
$611
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:55 am
IND
- PTY
1 stop13h 36m
United Airlines
Tue 9/159:45 am
PTY
- IND
1 stop11h 14m
United Airlines
Deal found 7/24![United Airlines logo]()
$612
Best flights from Indianapolis to PanamaDiscover carefully curated flight deals from Indianapolis to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 25, 2026.
Discover carefully curated flight deals from Indianapolis to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 25, 2026.
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:05 am
IND
- PTY
1 stop11h 57m
United Airlines
Tue 11/178:55 am
PTY
- IND
3 stops14h 46m
United Airlines
Deal found 7/23![United Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:51 am
IND
- PTY
1 stop9h 40m
United Airlines
Tue 10/273:41 pm
PTY
- IND
1 stop17h 58m
United Airlines
Deal found 7/20![United Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am
IND
- PTY
1 stop12h 37m
United Airlines
Mon 9/219:45 am
PTY
- IND
1 stop11h 14m
United Airlines
Deal found 7/24![United Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:00 am
IND
- PTY
1 stop12h 37m
United Airlines
Tue 9/293:30 pm
PTY
- IND
2 stops18h 26m
United Airlines
Deal found 7/25![United Airlines logo]()
$561
Last-minute flights from Indianapolis to PanamaDiscover last-minute flight deals from Indianapolis to Panama. Data last updated July 25, 2026 and is based on user searches.
Discover last-minute flight deals from Indianapolis to Panama. Data last updated July 25, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:00 am
IND
- PTY
1 stop12h 37m
United Airlines
Wed 7/2910:55 pm
PTY
- IND
1 stop12h 10m
United Airlines
Deal found 7/20![United Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:00 am
IND
- PTY
1 stop12h 37m
United Airlines
Sun 7/263:30 pm
PTY
- IND
1 stop18h 24m
United Airlines
Deal found 7/20![United Airlines logo]()
$695
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:26 pm
IND
- PTY
1 stop26h 11m
United Airlines
Mon 8/310:55 pm
PTY
- IND
1 stop14h 12m
United Airlines
Deal found 7/21![United Airlines logo]()
$673
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:50 am
IND
- PTY
1 stop7h 47m
United Airlines
Thu 8/133:30 pm
PTY
- IND
1 stop18h 18m
United Airlines
Deal found 7/20![United Airlines logo]()
$627
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:15 pm
IND
- PTY
1 stop13h 49m
United Airlines
Tue 8/183:30 pm
PTY
- IND
1 stop18h 18m
United Airlines
Deal found 7/24![United Airlines logo]()
$667
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:28 pm
IND
- PTY
2 stops19h 11m
American Airlines
Wed 8/261:39 pm
PTY
- IND
2 stops17h 47m
American Airlines
Deal found 7/20![American Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:15 pm
IND
- PTY
1 stop13h 49m
United Airlines
Mon 8/2410:55 pm
PTY
- IND
1 stop12h 01m
United Airlines
Deal found 7/22![United Airlines logo]()
$701
One-way flights from Indianapolis to PanamaSearch for one-way flight options from Indianapolis to Panama. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.
Search for one-way flight options from Indianapolis to Panama. Find affordable one-way fares based on user searches. Data last updated July 25, 2026.
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am
IND
- PTY
1 stop7h 58m
Delta
Deal found 7/25![Delta logo]()
$246
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:57 pm
IND
- PTY
2 stops18h 19m
American Airlines
Deal found 7/25![American Airlines logo]()
$256
This Avianca deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:43 pm
IND
- PTY
2 stops15h 47m
Avianca
Deal found 7/21![Avianca logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:11 pm
IND
- PTY
1 stop27h 20m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:11 pm
IND
- PTY
1 stop27h 20m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$336
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am
IND
- PTY
1 stop7h 39m
American Airlines
Deal found 7/22![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:00 am
IND
- PTY
2 stops11h 37m
United Airlines
Deal found 7/22![United Airlines logo]()
$358
Find flight deals from Indianapolis to Panama
Keep the following information in mind while searching for Indianapolis to Panama flight deals. Data was last updated July 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $557 (United Airlines) |
One-way from | $333 (Avianca) |
Popular in | December |
Cheapest in | February |
Average price | $686 |
Cheapflights Fare Finder
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Thu 11/12
8:05 am-8:02 pm
1 stop11h 57m
Panama City Tocumen Intl
Tue 11/17
8:55 am-11:41 pm
3 stops14h 46m
$557
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Mon 10/19
10:51 am-7:31 pm
1 stop9h 40m
Panama City Tocumen Intl
Tue 10/27
3:41 pm-10:39 am
1 stop17h 58m
$557
Quickest round-trip
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Mon 9/14
7:00 am-6:37 pm
1 stop12h 37m
Panama City Tocumen Intl
Mon 9/21
9:45 am-9:59 pm
1 stop11h 14m
$557
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Thu 9/24
7:00 am-6:37 pm
1 stop12h 37m
Panama City Tocumen Intl
Tue 9/29
3:30 pm-10:56 am
2 stops18h 26m
$561
Cheapest one-way
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Thu 9/24
6:00 am-12:58 pm
1 stop7h 58m
$246
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Fri 8/28
7:43 pm-10:30 am
2 stops15h 47m
$333
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Fri 8/21
6:11 pm-8:31 pm
1 stop27h 20m
$336
Quickest one-way
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Fri 8/21
6:00 am-12:39 pm
1 stop7h 39m
$338
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Fri 8/28
6:11 pm-2:05 pm
3 stops44h 54m
$354
IndianapolisPanama City
IND - PTY
INDPTY
Indianapolis
Wed 8/12
7:00 am-7:31 pm
2 stops13h 31m
$358
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Indianapolis to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Indianapolis with our price prediction graph.
IND-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indianapolis to Panama
IND-PA0
IND-PTY
What is the cheapest month to book a flight from Indianapolis to Panama?
Currently, February is the cheapest month in which you can book a flight from Indianapolis to Panama (average of $559). Flying from Indianapolis to Panama in December is currently the most expensive (average of $1,052). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 25, 2026.
Peruse reviews from past customers who have flown with Delta,Copa Airlines, andUnited Airlines from Indianapolis to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Indianapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Indianapolis to Panama
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Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indianapolis to Panama by cabin class
Find flights from Indianapolis to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indianapolis and Panama flights
Browse other Indianapolis and Panama flight options. Last updated on July 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Indianapolis to Panama
Discover the top 4 airlines that operate flights from Indianapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$426 | Average$649 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$509 | Average$644 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$519 | Average$776 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$556 | Average$710 | FlexibilityNo cancel fee | On-time70% |