$447+ Cheap flights from Panama to Indianapolis (IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Panama to Indianapolis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Indianapolis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to IndianapolisExplore the most affordable flight options available from Panama to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Panama to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1611:35 am -
2 stops12h 24m
Sun 1/36:08 pm -
1 stop25h 54m
Deal found 11/3![United Airlines logo]()
$728
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:48 pm -
2 stops21h 19m
Mon 12/77:39 pm -
1 stop24h 40m
Deal found 11/2![Multiple Airlines logo]()
$747
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:55 pm -
2 stops24h 04m
Wed 12/302:02 pm -
2 stops24h 43m
Deal found 11/1![United Airlines logo]()
$776
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:48 pm -
2 stops21h 19m
Thu 12/108:00 am -
1 stop12h 19m
Deal found 11/2![Multiple Airlines logo]()
$804
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:55 am -
1 stop11h 06m
Tue 12/87:50 am -
1 stop12h 12m
Deal found 11/2![United Airlines logo]()
$808
This Trip.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:30 am -
3 stops37h 12m
Fri 11/2710:56 am -
2 stops22h 14m
Deal found 11/1![Multiple Airlines logo]()
$809
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:00 am -
1 stop13h 39m
Sat 12/125:00 am -
2 stops14h 38m
Deal found 11/2![United Airlines logo]()
$816
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:00 am -
1 stop13h 44m
Tue 11/106:22 am -
1 stop13h 40m
Deal found 11/3![United Airlines logo]()
$817
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:00 pm -
2 stops27h 32m
Thu 12/108:00 am -
1 stop12h 19m
Deal found 11/2![Multiple Airlines logo]()
$820
Best flights from Panama to IndianapolisDiscover carefully curated flight deals from Panama to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Panama to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/174:41 pm -
1 stop23h 03m
Wed 12/305:10 pm -
1 stop26h 28m
Deal found 11/1![United Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1611:35 am -
2 stops12h 24m
Sun 1/36:08 pm -
1 stop25h 54m
Deal found 11/3![United Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/264:41 pm -
1 stop18h 06m
Fri 1/2911:30 am -
1 stop8h 08m
Deal found 11/1![United Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2210:00 am -
1 stop13h 41m
Mon 1/259:00 am -
1 stop8h 12m
Deal found 11/4![United Airlines logo]()
$750
Last-minute flights from Panama to IndianapolisDiscover last-minute flight deals from Panama to Indianapolis. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Indianapolis. Data last updated November 5, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:00 am -
1 stop13h 44m
Tue 11/106:22 am -
1 stop13h 40m
Deal found 11/3![United Airlines logo]()
$817
This Trip.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:30 am -
3 stops37h 12m
Fri 11/2710:56 am -
2 stops22h 14m
Deal found 11/1![Multiple Airlines logo]()
$809
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:55 am -
1 stop14h 25m
Fri 12/115:00 am -
2 stops14h 38m
Deal found 11/2![United Airlines logo]()
$816
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:48 pm -
2 stops21h 19m
Mon 12/77:39 pm -
1 stop24h 40m
Deal found 11/2![Multiple Airlines logo]()
$747
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:48 pm -
2 stops21h 19m
Thu 12/108:00 am -
1 stop12h 19m
Deal found 11/2![Multiple Airlines logo]()
$804
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:55 am -
1 stop11h 06m
Tue 12/87:50 am -
1 stop12h 12m
Deal found 11/2![United Airlines logo]()
$808
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:00 pm -
2 stops27h 32m
Thu 12/108:00 am -
1 stop12h 19m
Deal found 11/2![Multiple Airlines logo]()
$820
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1611:35 am -
2 stops12h 24m
Sun 1/36:08 pm -
1 stop25h 54m
Deal found 11/3![United Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:55 pm -
2 stops24h 04m
Wed 12/302:02 pm -
2 stops24h 43m
Deal found 11/1![United Airlines logo]()
$776
One-way flights from Panama to IndianapolisSearch for one-way flight options from Panama to Indianapolis. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Panama to Indianapolis. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/3110:00 am -
1 stop8h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/308:55 am -
1 stop25h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![United Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/3111:55 pm -
2 stops16h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![United Airlines logo]()
$461
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:33 pm -
2 stops20h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$465
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3012:10 pm -
3 stops30h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$533
This BusinessClass deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:55 am -
1 stop11h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Copa Airlines logo]()
$690
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:55 am -
2 stops13h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![United Airlines logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:08 am -
3 stops38h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$1,603
Find flight deals from Panama to Indianapolis
Keep the following information in mind while searching for Panama to Indianapolis flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $728 (United Airlines) |
One-way from | $447 (Kiwi.com) |
Popular in | June |
Cheapest in | April |
Average price | $760 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Panama to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Wed 12/30
8:55 am-10:42 am
1 stop25h 47m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$456
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Thu 12/31
11:55 pm-4:13 pm
2 stops16h 18m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$461
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Wed 12/30
4:33 pm-12:48 pm
2 stops20h 15m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$465
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Thu 12/31
12:10 pm-10:25 am
3 stops22h 15m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$550
Quickest round-trip
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Tue 11/10
8:55 am-8:02 pm
1 stop11h 07m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$690
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Tue 11/10
8:55 am-10:14 pm
2 stops13h 19m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$710
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Thu 12/17
4:41 pm-3:44 pm
1 stop23h 03m
Indianapolis
Wed 12/30
5:10 pm-7:38 pm
1 stop26h 28m
$728
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Wed 12/16
11:35 am-11:59 pm
2 stops12h 24m
Indianapolis
Sun 1/3
6:08 pm-8:02 pm
1 stop25h 54m
$728
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Tue 1/26
4:41 pm-10:47 am
1 stop18h 06m
Indianapolis
Fri 1/29
11:30 am-7:38 pm
1 stop8h 08m
$728
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Fri 1/22
10:00 am-11:41 pm
1 stop13h 41m
Indianapolis
Mon 1/25
9:00 am-5:12 pm
1 stop8h 12m
$750
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Panama to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama with our price prediction graph.
PTY-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Indianapolis
PA0-IND
PTY-IND
What is the cheapest month to book a flight from Panama to Indianapolis?
Currently, April is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $561). Flying from Panama to Indianapolis in June is currently the most expensive (average of $878). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated November 5, 2026.
See what other customers who have flown with Delta,Copa Airlines, andUnited Airlines from Panama to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsPlainfield
Greenwood
Terre Haute
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Bloomington
Speedway
Noblesville
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Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Panama and Indianapolis flights
Browse other Panama and Indianapolis flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Panama to Indianapolis
Discover the top 3 airlines that operate flights from Panama to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$307 | Average$792 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$468 | Average$643 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$581 | Average$711 | FlexibilityNo cancel fee | On-timeN/A |