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$335+ Cheap flights from Panama to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Sep 7 — Sep 141
Mon 9/7
Mon 9/14
1 adult, Economy
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Cheap flight deals from Panama to Indianapolis

Cheapest flights from Panama to Indianapolis
Explore the most affordable flight options available from Panama to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 8, 2026.

This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:00 am -
1 stop12h 30m
Mon 9/285:40 am -
2 stops14h 51m
Deal found 8/4$583
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
2 stops18h 26m
Tue 10/69:00 am -
1 stop11h 31m
Deal found 8/4$604
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:00 am -
1 stop9h 29m
Mon 10/59:00 am -
1 stop11h 31m
Deal found 8/3$632
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:00 am -
1 stop12h 30m
Tue 9/297:00 am -
1 stop12h 37m
Deal found 8/6$653
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:45 am -
2 stops24h 11m
Sat 10/107:01 pm -
2 stops25h 30m
Deal found 8/7$684
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:00 am -
2 stops12h 40m
Sun 9/275:40 am -
2 stops14h 51m
Deal found 8/6$748
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/103:30 pm -
2 stops20h 17m
Thu 8/277:00 am -
2 stops22h 04m
Deal found 8/5$751
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:45 am -
1 stop21h 38m
Mon 8/106:55 pm -
1 stop10h 09m
Deal found 8/4$771

Find flight deals from Panama to Indianapolis

Keep the following information in mind while searching for Panama to Indianapolis flight deals. Data was last updated August 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$583
(United Airlines)

One-way from

$335
(United Airlines)

Popular in

June

Cheapest in

November

Average price

$638
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
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From Panama to Indianapolis
Search Deals
One-way flight from Panama to Indianapolis
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 8, 2026.
Use the filters below to find and compare flights from Panama to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityIndianapolis

PTY Panama City Tocumen Intl - IND Indianapolis

PTYIND

Panama City Tocumen Intl

Thu 9/24

10:00 am-11:30 pm

1 stop12h 30m

Indianapolis

Mon 9/28

5:40 am-7:31 pm

2 stops14h 51m

$583

Panama CityIndianapolis

PTY Panama City Tocumen Intl - IND Indianapolis

PTYIND

Panama City Tocumen Intl

Mon 2/1

4:41 pm-3:57 pm

1 stop23h 16m

Indianapolis

Sun 2/28

5:03 pm-7:38 pm

1 stop26h 35m

$604
Quickest round-trip

Panama CityIndianapolis

PTY Panama City Tocumen Intl - IND Indianapolis

PTYIND

Panama City Tocumen Intl

Fri 10/2

10:00 am-8:29 pm

1 stop9h 29m

Indianapolis

Mon 10/5

9:00 am-7:31 pm

1 stop11h 31m

$632

Panama CityIndianapolis

PTY Panama City Tocumen Intl - IND Indianapolis

PTYIND

Panama City Tocumen Intl

Fri 9/25

3:30 pm-10:56 am

2 stops18h 26m

Indianapolis

Tue 9/29

7:00 am-6:37 pm

1 stop12h 37m

$658
Cheapest one-way

Panama CityIndianapolis

PTY Panama City Tocumen Intl - IND Indianapolis

PTYIND

Panama City Tocumen Intl

Thu 10/1

3:30 pm-10:48 am

1 stop18h 18m

$335

Panama CityIndianapolis

PTY Panama City Tocumen Intl - IND Indianapolis

PTYIND

Panama City Tocumen Intl

Sat 11/7

3:24 pm-12:35 am

1 stop9h 11m

$364
Quickest one-way

Panama CityIndianapolis

PTY Panama City Tocumen Intl - IND Indianapolis

PTYIND

Panama City Tocumen Intl

Sat 11/7

3:13 pm-10:58 pm

1 stop7h 45m

$369

Panama CityIndianapolis

PTY Panama City Tocumen Intl - IND Indianapolis

PTYIND

Panama City Tocumen Intl

Sat 11/7

10:00 am-6:59 pm

1 stop8h 59m

$369

Panama CityIndianapolis

PTY Panama City Tocumen Intl - IND Indianapolis

PTYIND

Panama City Tocumen Intl

Sun 11/8

8:55 am-8:02 pm

1 stop11h 07m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/7

Sorted by cheapest first

Best time to book a flight from Panama to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Indianapolis

What is the cheapest month to book a flight from Panama to Indianapolis?

Currently, November is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $526). Flying from Panama to Indianapolis in June is currently the most expensive (average of $878). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated August 8, 2026.
See what other customers who have flown with Copa Airlines and United Airlines from Panama to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,563 reviews

Overall

7.6

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.9

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.6
Good
1,563 reviews
Copa Airlines
7.6
Good
1,563 reviews

Overall

7.6

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.9

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
United Airlines
7.4
Good
10,086 reviews
Copa Airlines
7.6
Good
1,563 reviews

Overall

7.6

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.9

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Panama to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Panama?

    For a flight from Panama to Indianapolis, you will be flying into Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Panama to Indianapolis?

    A quick flight from Panama to Indianapolis can take about 12h 30m. United Airlines provides one of the quickest options available for as low as $583. Panama and Indianapolis are separated by a distance of 2158 mi.

  • Can I find deals for flights from Panama to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Indianapolis.

  • Can I find deals for business class flights from Panama to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Indianapolis?

    Currently, November is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $526). Flying from Panama to Indianapolis in June is currently the most expensive (average of $878). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Greenwood
Kokomo
Fishers
Westfield
Franklin
Mooresville
Plainfield
Anderson
Crawfordsville
Carmel
Noblesville
Bloomington
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Panama to Indianapolis

Discover the top 2 airlines that operate flights from Panama to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$719FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$468Average$643FlexibilityNo cancel feeOn-time70%

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