$345+ Cheap flights from Panama to Indianapolis (IND)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama to IndianapolisExplore the most affordable flight options available from Panama to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from Panama to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:41 pm -
1 stop22h 53m
Tue 11/1711:40 am -
1 stop7h 58m
Deal found 9/23![United Airlines logo]()
$615
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:34 pm -
2 stops18h 39m
Wed 12/25:11 pm -
2 stops21h 02m
Deal found 9/20![American Airlines logo]()
$634
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:24 pm -
1 stop9h 01m
Mon 11/96:00 am -
1 stop8h 02m
Deal found 9/19![Delta logo]()
$686
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:55 am -
1 stop14h 24m
Tue 11/1011:01 am -
1 stop9h 01m
Deal found 9/21![United Airlines logo]()
$688
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:41 pm -
1 stop18h 01m
Wed 12/26:30 am -
1 stop8h 15m
Deal found 9/19![United Airlines logo]()
$702
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:55 am -
1 stop14h 24m
Sun 11/297:00 am -
1 stop7h 45m
Deal found 9/23![United Airlines logo]()
$704
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:30 pm -
1 stop18h 18m
Sun 10/256:33 pm -
2 stops25h 29m
Deal found 9/22![United Airlines logo]()
$711
Best flights from Panama to IndianapolisDiscover carefully curated flight deals from Panama to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from Panama to Indianapolis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:41 pm -
2 stops20h 03m
Tue 12/17:15 am -
2 stops12h 23m
Deal found 9/20![United Airlines logo]()
$615
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:34 pm -
2 stops19h 04m
Sun 11/296:00 am -
1 stop8h 34m
Deal found 9/23![American Airlines logo]()
$729
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:55 am -
1 stop14h 24m
Tue 11/179:10 am -
2 stops10h 28m
Deal found 9/21![United Airlines logo]()
$629
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/248:55 am -
1 stop14h 32m
Sun 1/316:30 pm -
1 stop25h 32m
Deal found 9/19![United Airlines logo]()
$655
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:55 am -
1 stop14h 24m
Tue 11/1011:01 am -
1 stop9h 01m
Deal found 9/21![United Airlines logo]()
$688
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/154:41 pm -
1 stop18h 19m
Sat 1/2310:20 am -
1 stop9h 42m
Deal found 9/19![United Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:41 pm -
1 stop18h 01m
Wed 12/26:30 am -
1 stop8h 15m
Deal found 9/19![United Airlines logo]()
$702
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:55 am -
1 stop14h 24m
Sun 11/297:00 am -
1 stop7h 45m
Deal found 9/23![United Airlines logo]()
$704
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/14:41 pm -
1 stop18h 19m
Fri 2/126:40 pm -
2 stops22h 32m
Deal found 9/20![United Airlines logo]()
$729
Last-minute flights from Panama to IndianapolisDiscover last-minute flight deals from Panama to Indianapolis. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Indianapolis. Data last updated September 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:16 pm -
1 stop9h 01m
Mon 10/125:23 pm -
2 stops20h 39m
Deal found 9/21![American Airlines logo]()
$725
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:23 pm -
1 stop9h 09m
Mon 10/127:00 am -
1 stop6h 59m
Deal found 9/23![Delta logo]()
$751
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:30 pm -
2 stops20h 12m
Mon 10/127:00 am -
1 stop12h 37m
Deal found 9/22![United Airlines logo]()
$765
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:30 pm -
1 stop18h 18m
Mon 10/59:00 am -
1 stop11h 31m
Deal found 9/22![United Airlines logo]()
$792
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:23 pm -
1 stop9h 09m
Mon 10/127:00 am -
1 stop6h 59m
Deal found 9/20![Delta logo]()
$783
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:30 pm -
1 stop18h 18m
Sun 10/256:33 pm -
2 stops25h 29m
Deal found 9/22![United Airlines logo]()
$711
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:02 pm -
2 stops19h 44m
Fri 10/306:00 am -
1 stop8h 02m
Deal found 9/23![American Airlines logo]()
$778
One-way flights from Panama to IndianapolisSearch for one-way flight options from Panama to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from Panama to Indianapolis. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:41 pm -
1 stop18h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![United Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/43:30 pm -
2 stops24h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$484
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:33 pm -
2 stops20h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$512
This Avianca deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:25 am -
3 stops25h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Avianca logo]()
$567
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:48 pm -
3 stops24h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$610
Find flight deals from Panama to Indianapolis
Keep the following information in mind while searching for Panama to Indianapolis flight deals. Data was last updated September 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $615 (United Airlines) |
One-way from | $484 (United Airlines) |
Popular in | June |
Cheapest in | April |
Average price | $751 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Panama to Indianapolis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Wed 12/30
4:41 pm-10:42 am
1 stop18h 01m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$345
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Sun 10/4
3:30 pm-3:40 pm
1 stop23h 10m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$484
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Tue 11/24
4:41 pm-12:44 pm
2 stops20h 03m
Indianapolis
Tue 12/1
7:15 am-7:38 pm
2 stops12h 23m
$615
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Thu 11/12
8:55 am-11:19 pm
1 stop14h 24m
Indianapolis
Tue 11/17
9:10 am-7:38 pm
2 stops10h 28m
$629
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Sun 1/24
8:55 am-11:27 pm
1 stop14h 32m
Indianapolis
Sun 1/31
6:30 pm-8:02 pm
1 stop25h 32m
$655
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Wed 11/4
8:55 am-11:19 pm
1 stop14h 24m
Indianapolis
Tue 11/10
11:01 am-8:02 pm
1 stop9h 01m
$688
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Fri 1/15
4:41 pm-11:00 am
1 stop18h 19m
Indianapolis
Sat 1/23
10:20 am-8:02 pm
1 stop9h 42m
$694
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Wed 11/25
4:41 pm-10:42 am
1 stop18h 01m
Indianapolis
Wed 12/2
6:30 am-2:45 pm
1 stop8h 15m
$702
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Mon 11/23
8:55 am-11:19 pm
1 stop14h 24m
Indianapolis
Sun 11/29
7:00 am-2:45 pm
1 stop7h 45m
$704
Panama CityIndianapolis
PTY Panama City Tocumen Intl - IND Indianapolis
PTYIND
Panama City Tocumen Intl
Mon 11/23
3:34 pm-10:38 am
2 stops19h 04m
Indianapolis
Sun 11/29
6:00 am-2:34 pm
1 stop8h 34m
$729
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Panama to Indianapolis
Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama with our price prediction graph.
PTY-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Indianapolis
PA0-IND
PTY-IND
What is the cheapest month to book a flight from Panama to Indianapolis?
Currently, April is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $561). Flying from Panama to Indianapolis in June is currently the most expensive (average of $878). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Indianapolis
Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated September 23, 2026.
See what other customers who have flown with Delta,Copa Airlines, andUnited Airlines from Panama to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Food
7.2
Comfort
7.8
Boarding
8.1
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Panama to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Indianapolis?
Book flights to Indianapolis if you plan to visit one of these locationsTerre Haute
Greenwood
Plainfield
Fishers
Muncie
Kokomo
Westfield
Franklin
Mooresville
Crawfordsville
Anderson
Carmel
Noblesville
Bloomington
Speedway
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Other flights to Indianapolis
Explore flights to Indianapolis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 23, 2026.
Panama and Indianapolis flights
Browse other Panama and Indianapolis flight options. Last updated on September 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Panama to Indianapolis
Discover the top 3 airlines that operate flights from Panama to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$307 | Average$785 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$468 | Average$643 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$581 | Average$615 | FlexibilityNo cancel fee | On-timeN/A |