Indiana

$284+ Cheap flights from Panama to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Jun 8 — Jun 151
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama to Indiana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama to Indiana

Cheapest flights from Panama to Indiana
Explore the most affordable flight options available from Panama to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.

This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:21 pm
PTY
-
IND
1 stop9h 13m
Delta
Tue 10/66:00 am
IND
-
PTY
1 stop7h 56m
Delta
Deal found 5/7$508
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:40 pm
PTY
-
IND
2 stops19h 22m
American Airlines
Tue 10/68:11 pm
IND
-
PTY
2 stops18h 49m
American Airlines
Deal found 5/7$525
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:35 pm
PTY
-
CVG
2 stops19h 31m
American Airlines
Sun 10/188:22 pm
CVG
-
PTY
2 stops18h 38m
American Airlines
Deal found 5/6$551
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:30 pm
PTY
-
SDF
2 stops16h 57m
United Airlines
Fri 7/319:30 am
SDF
-
PTY
1 stop10h 07m
United Airlines
Deal found 5/6$589
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/232:24 pm
PTY
-
IND
1 stop9h 17m
Delta
Mon 7/277:01 am
IND
-
PTY
1 stop7h 04m
Delta
Deal found 5/5$591
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/12:43 pm
PTY
-
IND
2 stops21h 32m
American Airlines
Sun 11/83:38 pm
IND
-
PTY
2 stops21h 58m
American Airlines
Deal found 5/7$595
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:30 pm
PTY
-
SDF
2 stops20h 31m
United Airlines
Tue 9/15:35 am
SDF
-
PTY
2 stops14h 56m
United Airlines
Deal found 5/6$603
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:49 pm
PTY
-
IND
1 stop9h 10m
American Airlines
Tue 5/196:01 am
IND
-
PTY
1 stop7h 45m
American Airlines
Deal found 5/7$613
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:15 pm
PTY
-
IND
1 stop9h 18m
Delta
Tue 5/196:00 am
IND
-
PTY
1 stop7h 50m
Delta
Deal found 5/4$615
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:49 pm
PTY
-
CVG
2 stops19h 36m
American Airlines
Tue 5/125:31 pm
CVG
-
PTY
2 stops20h 15m
American Airlines
Deal found 5/5$618
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/101:24 pm
PTY
-
SDF
2 stops25h 07m
American Airlines
Fri 8/147:12 pm
SDF
-
PTY
2 stops18h 12m
American Airlines
Deal found 5/8$619
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:15 pm
PTY
-
IND
1 stop9h 18m
Delta
Tue 6/96:00 am
IND
-
PTY
1 stop8h 09m
Delta
Deal found 5/8$623

Find flight deals from Panama to Indiana

Keep the following information in mind while searching for Panama to Indiana flight deals. Data was last updated May 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$508
(Delta)

One-way from

$284
(Kiwi.com)

Popular in

March

Cheapest in

November

Average price

$590
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
From Panama to Indiana
One-way flight from Panama to Indiana
Highest demand for flights based on searches. 7% potential increase in price ($54 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
Use the filters below to find and compare flights from Panama to Indiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 7/21

3:30 pm-9:27 am

2 stops16h 57m

Louisville Intl

Fri 7/31

9:30 am-6:37 pm

1 stop10h 07m

$589

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 7/21

9:45 am-10:55 pm

1 stop12h 10m

Louisville Intl

Wed 8/5

6:15 am-4:12 pm

1 stop10h 57m

$589

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 8/28

3:30 pm-9:15 am

2 stops16h 45m

Louisville Intl

Tue 9/1

6:15 am-7:31 pm

1 stop14h 16m

$603

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 8/10

1:24 pm-3:31 pm

2 stops25h 07m

Louisville Intl

Fri 8/14

7:12 pm-12:24 pm

2 stops18h 12m

$619

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Fri 5/29

2:15 pm-12:33 am

1 stop9h 18m

Indianapolis

Tue 6/9

6:00 am-1:09 pm

1 stop8h 09m

$623

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 7/22

10:55 pm-8:57 pm

1 stop21h 02m

Indianapolis

Mon 7/27

9:05 am-4:04 am

1 stop19h 59m

$645

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 7/23

10:00 am-9:28 am

2 stops22h 28m

Indianapolis

Mon 7/27

8:10 pm-2:14 pm

2 stops19h 04m

$645

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 9/22

3:30 pm-4:29 pm

2 stops23h 59m

Indianapolis

Wed 9/23

7:59 pm-2:14 pm

2 stops19h 15m

$653

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 9/22

10:00 am-10:14 pm

1 stop11h 14m

Louisville Intl

Wed 9/23

7:10 am-6:37 pm

1 stop12h 27m

$654

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 6/1

3:30 pm-1:35 pm

2 stops21h 05m

Louisville Intl

Thu 9/10

7:43 pm-7:31 pm

2 stops24h 48m

$660

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/6

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Panama to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Indiana

What is the cheapest month to book a flight from Panama to Indiana?

Currently, June is the cheapest month in which you can book a flight from Panama to Indiana (average of $203). Flying from Panama to Indiana in February is currently the most expensive (average of $678). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated May 9, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andUnited Airlines from Panama to Indiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Panama to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Panama to Indiana?

    There are many flights that can get you from Panama to Indiana in 5h 36m. Fly via United Airlines, Delta, or Copa Airlines to get the fastest option. The distance from Panama to Indiana is about 2330 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama to Indiana that include hotel bookings?

    Yes. In addition to deals on Panama to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Indiana.

  • Can I find deals for business class flights from Panama to Indiana?

    Yes. Cheapflights offers flight deals from Panama to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Indiana?

    Currently, June is the cheapest month in which you can book a flight from Panama to Indiana (average of $203). Flying from Panama to Indiana in February is currently the most expensive (average of $678). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to Indiana

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Panama to Indiana

Discover the top 3 airlines that operate flights from Panama to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$307Average$727FlexibilityNo cancel feeOn-time69%
DeltaCheapest$311Average$612FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$468Average$643FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.