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Panama City

$164+ Cheap flights from Indiana to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Cheap flight deals from Indiana to Panama City

Keep the following information in mind while searching for Indiana to Panama City flight deals. Data was last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$428
(American Airlines)

One-way from

$164
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$619
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
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From Indiana to Panama City Tocumen Intl
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One-way flight from Indiana to Panama City Tocumen Intl
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Highest demand for flights based on searches. 9% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Indiana to Panama City

Cheapest flights from Indiana to Panama City
Explore the most affordable flight options available from Indiana to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:10 amSDF - PTY
1 stop7h 35mUnited Airlines
Sun 12/78:55 amPTY - SDF
1 stop13h 02mUnited Airlines
Deal found 11/20$444
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:20 pmSDF - PTY
2 stops20h 27mAmerican Airlines
Sun 12/74:43 pmPTY - SDF
2 stops20h 28mAmerican Airlines
Deal found 11/20$453
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:31 amSDF - PTY
1 stop10h 07mUnited Airlines
Mon 12/158:55 amPTY - SDF
1 stop10h 59mUnited Airlines
Deal found 11/20$465
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:40 amORD - PTY
1 stop7h 57mMultiple Airlines
Sat 12/610:25 amPTY - ORD
1 stop9h 11mMultiple Airlines
Deal found 11/18$485
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:00 amORD - PTY
2 stops11h 16mMultiple Airlines
Tue 12/28:11 amPTY - ORD
1 stop30h 04mMultiple Airlines
Deal found 11/18$528
This Cheapflightsfares deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:20 pmORD - PTY
1 stop14h 40mAvianca
Sun 12/142:55 amPTY - ORD
1 stop18h 25mAvianca
Deal found 11/20$535
This Cheapflightsfares deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:20 pmORD - PTY
1 stop14h 40mAvianca
Sun 12/72:55 amPTY - ORD
1 stop18h 25mAvianca
Deal found 11/19$541
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:05 pmCVG - PTY
1 stop21h 37mAmerican Airlines
Sat 1/172:27 pmPTY - CVG
2 stops20h 19mAmerican Airlines
Deal found 11/18$546
This Avianca deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:20 pmORD - PTY
1 stop17h 35mAvianca
Wed 12/109:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 11/19$563
This Priceline deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2410:20 pmORD - PTY
1 stop14h 40mAvianca
Mon 12/19:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 11/18$571
This Trip.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:41 pmORD - PTY
2 stops37h 49mMultiple Airlines
Mon 12/152:55 amPTY - ORD
2 stops16h 41mMultiple Airlines
Deal found 11/18$581
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/14:58 pmORD - PTY
2 stops20h 57mMultiple Airlines
Mon 12/82:55 pmPTY - ORD
3 stops34h 14mMultiple Airlines
Deal found 11/19$584

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Indiana to Panama City that are best for you.

Fly from

Indiana

Fly to

Panama City

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sun 1/18

6:12 pm-5:07 pm

2 stops22h 55m

Panama City Tocumen Intl

Thu 1/22

4:41 pm-1:28 pm

2 stops20h 47m

$428

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 1/9

8:30 am-8:02 pm

1 stop11h 32m

Panama City Tocumen Intl

Thu 2/5

8:55 am-9:59 pm

1 stop13h 04m

$431

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 2/14

6:00 am-5:07 pm

1 stop11h 07m

Panama City Tocumen Intl

Thu 2/19

11:35 am-9:46 pm

1 stop10h 11m

$431

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 5/16

6:21 pm-12:15 pm

2 stops18h 54m

Panama City Tocumen Intl

Tue 6/2

1:50 pm-10:13 am

2 stops19h 23m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 5/16

8:15 pm-12:15 pm

2 stops17h 00m

Panama City Tocumen Intl

Wed 6/3

1:50 pm-9:04 am

2 stops18h 14m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 2/28

3:49 pm-1:40 pm

2 stops21h 51m

Panama City Tocumen Intl

Thu 3/5

4:04 pm-3:03 pm

2 stops22h 59m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 5/16

6:00 pm-2:14 pm

2 stops21h 14m

Panama City Tocumen Intl

Wed 6/3

10:00 am-9:30 pm

1 stop10h 30m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 2/28

5:54 pm-5:07 pm

2 stops23h 13m

Panama City Tocumen Intl

Thu 3/5

11:35 am-9:59 pm

1 stop10h 24m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 3/7

9:00 am-5:10 am

2 stops20h 10m

Panama City Tocumen Intl

Thu 3/12

3:41 pm-1:17 pm

2 stops20h 36m

$435

Fort WaynePanama City

FWA - PTY

FWAPTY

Fort Wayne

Mon 2/2

2:14 pm-1:55 pm

2 stops23h 41m

Panama City Tocumen Intl

Thu 2/5

3:20 pm-1:34 pm

2 stops22h 14m

$440

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Panama City

What is the cheapest month to book a flight from Indiana to Panama City?

Currently, September is the cheapest month in which you can book a flight from Indiana to Panama City (average of $463). Flying from Indiana to Panama City in December is currently the most expensive (average of $570). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to PTY?

Find hourly flight availability from Indiana to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from Indiana to Panama City by exploring options for tickets in the evening.

How much does it cost to fly round-trip from Indiana to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Indiana to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Indiana?

    Panama City Tocumen Intl (PTY) is the airport you will fly into if you book a flight from Indiana to Panama City. It is only a 11.4 mi journey from Tocumen Intl (PTY) to Panama City’s city center.

  • How long is the flight from Indiana to Panama City?

    Airlines like United Airlines, American Airlines, and Delta fly from Indiana to Panama City in about 18h 54m. The time it takes to get you to your destination can typically vary by up to 4h 47m. The distance from Indiana to Panama City is about 2048 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Indiana to Panama City one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $232. Users have also found prices from $232 and $232 on Delta and American Airlines, respectively.

  • What are the most popular routes from Indiana to Panama City?

    While some choose either Chicago Midway - Panama City Tocumen Intl or Cincinnati Cinci./N. Kentucky - Panama City Tocumen Intl, Chicago O'Hare Intl - Panama City Tocumen Intl is the most popular route from Indiana to Panama City.

  • Can I find deals for flights from Indiana to Panama City that include hotel bookings?

    Yes. In addition to deals on Indiana to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Panama City.

  • Can I find deals for business class flights from Indiana to Panama City?

    Yes. Cheapflights offers flight deals from Indiana to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Indiana to Panama City (average of $463). Flying from Indiana to Panama City in December is currently the most expensive (average of $570). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indiana to Panama City

Discover the top 3 airlines that operate flights from Indiana to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$672FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$606FlexibilityNo cancel feeOn-time69%
DeltaCheapest$473Average$614FlexibilityNo cancel feeOn-timeN/A

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