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Panama City

$146+ Cheap flights from Indiana to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Nov 5 — Nov 121
Wed 11/5
Wed 11/12
1 adult, Economy
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Cheap flight deals from Indiana to Panama City

Keep the following information in mind while searching for Indiana to Panama City flight deals. Data was last updated October 6, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$367
(Avianca Connect)

One-way from

$146
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$639
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
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From Indiana to Panama City Tocumen Intl
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One-way flight from Indiana to Panama City Tocumen Intl
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Highest demand for flights based on searches. 9% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Indiana to Panama City

Cheapest flights from Indiana to Panama City
Explore the most affordable flight options available from Indiana to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 6, 2025.

This Avianca Connect deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/110:15 amIND - PTY
2 stops15h 45mMultiple Airlines
Tue 11/42:55 amPTY - IND
2 stops20h 34mMultiple Airlines
Deal found 10/4$367
This Mytrip deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:00 amIND - PTY
2 stops19h 10mMultiple Airlines
Sun 10/262:55 amPTY - IND
3 stops29h 25mMultiple Airlines
Deal found 10/6$422
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:00 amSDF - PTY
1 stop8h 12mDelta
Tue 11/253:37 pmPTY - SDF
1 stop8h 29mDelta
Deal found 10/4$424
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:00 amSDF - PTY
1 stop7h 49mAmerican Airlines
Tue 11/252:43 pmPTY - SDF
2 stops19h 28mAmerican Airlines
Deal found 10/4$428
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:10 amSDF - PTY
1 stop12h 28mUnited Airlines
Wed 1/710:00 amPTY - SDF
1 stop9h 31mUnited Airlines
Deal found 10/5$431
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:10 amSDF - PTY
1 stop12h 28mUnited Airlines
Mon 11/178:55 amPTY - SDF
1 stop13h 02mUnited Airlines
Deal found 10/5$433
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:07 pmSDF - PTY
2 stops21h 38mUnited Airlines
Tue 11/48:55 amPTY - SDF
2 stops25h 04mUnited Airlines
Deal found 10/4$437
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:00 amSDF - PTY
1 stop11h 07mUnited Airlines
Mon 1/124:41 pmPTY - SDF
2 stops24h 56mUnited Airlines
Deal found 10/5$443
This Mytrip deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:34 pmORD - PTY
3 stops36h 16mMultiple Airlines
Wed 11/1211:25 amPTY - ORD
2 stops14h 02mMultiple Airlines
Deal found 10/6$451
This Mytrip deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:05 amORD - PTY
2 stops19h 55mMultiple Airlines
Sat 11/12:55 amPTY - ORD
2 stops22h 32mMultiple Airlines
Deal found 10/4$452
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:34 amSDF - PTY
1 stop8h 21mUnited Airlines
Fri 11/74:41 pmPTY - SDF
2 stops17h 17mUnited Airlines
Deal found 10/5$457
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/310:52 amORD - PTY
1 stop8h 27mMultiple Airlines
Fri 11/712:03 pmPTY - ORD
1 stop13h 24mMultiple Airlines
Deal found 10/5$460

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 6, 2025.
Use the filters below to find and compare flights from Indiana to Panama City that are best for you.

Fly from

Indiana

Fly to

Panama City

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 10/23

6:00 am-12:10 am

2 stops19h 10m

Panama City Tocumen Intl

Sun 10/26

2:55 am-9:20 am

3 stops29h 25m

$422

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 12/9

7:10 am-5:07 pm

1 stop9h 57m

Panama City Tocumen Intl

Wed 1/7

10:00 am-7:31 pm

1 stop9h 31m

$424

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 4/1

11:00 am-7:31 pm

1 stop9h 31m

Panama City Tocumen Intl

Sun 4/12

10:00 am-9:30 pm

1 stop10h 30m

$431

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 12/12

7:10 am-7:38 pm

1 stop12h 28m

Panama City Tocumen Intl

Wed 1/7

10:00 am-7:31 pm

1 stop9h 31m

$431

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 11/14

7:10 am-7:38 pm

1 stop12h 28m

Panama City Tocumen Intl

Mon 11/17

8:55 am-9:57 pm

1 stop13h 02m

$433

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 11/1

6:07 pm-2:45 pm

2 stops21h 38m

Panama City Tocumen Intl

Tue 11/4

8:55 am-9:59 am

2 stops25h 04m

$437

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 1/22

8:30 am-8:02 pm

1 stop11h 32m

Panama City Tocumen Intl

Sun 1/25

4:41 pm-9:59 pm

1 stop29h 18m

$439

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 12/18

6:00 am-5:07 pm

1 stop11h 07m

Panama City Tocumen Intl

Mon 1/12

4:41 pm-5:37 pm

2 stops24h 56m

$443

Fort WaynePanama City

FWA - PTY

FWAPTY

Fort Wayne

Tue 3/3

6:00 am-8:02 pm

2 stops14h 02m

Panama City Tocumen Intl

Tue 3/10

10:55 pm-4:25 pm

2 stops16h 30m

$472

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 2/18

6:35 am-12:40 am

2 stops18h 05m

Panama City Tocumen Intl

Tue 2/24

2:55 am-10:56 pm

2 stops20h 01m

$487

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/4

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Panama City

What is the cheapest month to book a flight from Indiana to Panama City?

Currently, September is the cheapest month in which you can book a flight from Indiana to Panama City (average of $463). Flying from Indiana to Panama City in August is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to PTY?

Find hourly flight availability from Indiana to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 6, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 22% on flights from Indiana to Panama City by exploring options for tickets in the evening.

How much does it cost to fly round-trip from Indiana to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Indiana to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Indiana?

    Panama City Tocumen Intl (PTY) is the airport you will fly into if you book a flight from Indiana to Panama City. It is only a 11.4 mi journey from Tocumen Intl (PTY) to Panama City’s city center.

  • How long is the flight from Indiana to Panama City?

    Airlines like United Airlines, Delta, and Avianca fly from Indiana to Panama City in about 6h 54m. The time it takes to get you to your destination can typically vary by up to 11h 26m. The distance from Indiana to Panama City is about 2063 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Indiana to Panama City one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $179. Users have also found prices from $186 and $232 on United Airlines and Avianca, respectively.

  • What are the most popular routes from Indiana to Panama City?

    While some choose either Cincinnati Cinci./N. Kentucky - Panama City Tocumen Intl or Chicago Midway - Panama City Tocumen Intl, Chicago O'Hare Intl - Panama City Tocumen Intl is the most popular route from Indiana to Panama City.

  • Can I find deals for flights from Indiana to Panama City that include hotel bookings?

    Yes. In addition to deals on Indiana to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Panama City.

  • Can I find deals for business class flights from Indiana to Panama City?

    Yes. Cheapflights offers flight deals from Indiana to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Indiana to Panama City (average of $463). Flying from Indiana to Panama City in August is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indiana to Panama City

Discover the top 3 airlines that operate flights from Indiana to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$463Average$672FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$604FlexibilityNo cancel feeOn-time69%
DeltaCheapest$473Average$619FlexibilityNo cancel feeOn-timeN/A

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