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Panama City

$108+ Cheap flights from Chicago (CHI) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — PTY
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Chicago to Panama City Tocumen Intl are usually found in November or July, booked 56 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Chicago to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$272
(Cheapflightsfares)

One-way from

$108
(Priceline)

Popular in

December

Cheapest in

November

Average price

$548

Good round-trip deal

$404 or less

Good one-way deal

$165 or less
From Chicago (CHI) to Panama City Tocumen Intl
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One-way flight from Chicago (CHI) to Panama City Tocumen Intl
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Highest demand for flights based on searches. 3% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Chicago (CHI) to Panama City Tocumen Intl.
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Price to beat on a one-way flight from Chicago (CHI) to Panama City Tocumen Intl.
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Find flight deals from Chicago to Panama City

Cheapest flights from Chicago to Panama City
Explore the most affordable flight options available from Chicago to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/173:07 pmORD - PTY
Nonstop5h 28mCopa Airlines
Fri 10/246:45 pmPTY - ORD
Nonstop5h 36mCopa Airlines
Deal found 9/15$451
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:05 amORD - PTY
2 stops19h 05mMultiple Airlines
Thu 10/235:25 pmPTY - ORD
2 stops30h 20mMultiple Airlines
Deal found 9/15$453
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1510:20 pmORD - PTY
1 stop17h 35mAvianca
Mon 12/297:50 pmPTY - ORD
1 stop20h 00mAvianca
Deal found 9/13$455
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:55 pmORD - PTY
1 stop18h 19mUnited Airlines
Sun 10/123:30 pmPTY - ORD
1 stop8h 44mUnited Airlines
Deal found 9/14$456
This Cheapflightsfares deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2010:20 pmORD - PTY
1 stop9h 30mAvianca
Mon 11/249:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 9/12$457
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/152:35 pmORD - PTY
1 stop10h 10mAvianca
Mon 9/2210:05 pmPTY - ORD
2 stops20h 41mAvianca
Deal found 9/13$461
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1311:55 amORD - PTY
1 stop8h 24mMultiple Airlines
Mon 10/2012:03 pmPTY - ORD
1 stop11h 42mMultiple Airlines
Deal found 9/14$462
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amMDW - PTY
1 stop7h 12mDelta
Wed 12/33:46 pmPTY - MDW
1 stop8h 46mDelta
Deal found 9/15$465
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:00 amORD - PTY
1 stop8h 14mUnited Airlines
Sat 10/183:30 pmPTY - ORD
1 stop18h 40mUnited Airlines
Deal found 9/15$465
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:56 amORD - PTY
Nonstop5h 26mCopa Airlines
Sun 11/307:50 amPTY - ORD
Nonstop5h 56mCopa Airlines
Deal found 9/14$466
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/159:32 amMDW - PTY
2 stops9h 27mDelta
Sat 11/223:37 pmPTY - MDW
1 stop8h 55mDelta
Deal found 9/13$470
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/178:44 pmORD - PTY
2 stops17h 19mAmerican Airlines
Fri 10/243:15 pmPTY - ORD
1 stop17h 38mAmerican Airlines
Deal found 9/14$470

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Chicago to Panama City that are best for you.

Fly from

Chicago

Fly to

Panama City

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/23

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Mon 10/27

7:55 am-1:41 pm

Nonstop5h 46m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 10/17

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Fri 10/24

6:45 pm-12:21 am

Nonstop5h 36m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 10/21

7:59 am-1:21 pm

Nonstop5h 22m

Panama City Tocumen Intl

Sat 10/25

6:45 pm-12:21 am

Nonstop5h 36m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 10/12

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Fri 10/17

6:45 pm-12:21 am

Nonstop5h 36m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 10/18

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Thu 10/23

6:45 pm-12:21 am

Nonstop5h 36m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/8

2:13 pm-8:35 pm

Nonstop5h 22m

Panama City Tocumen Intl

Thu 1/15

5:37 pm-10:21 pm

Nonstop5h 44m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 10/29

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Mon 12/8

7:56 am-12:52 pm

Nonstop5h 56m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 10/17

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Tue 10/21

6:45 pm-12:21 am

Nonstop5h 36m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 11/1

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Sat 11/8

7:20 pm-12:05 am

Nonstop5h 45m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 11/6

2:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Sun 11/9

7:20 pm-12:05 am

Nonstop5h 45m

$451

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 34 results
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The best insider tips for Chicago to Panama City flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Chicago to Panama City trip
Airports
ORD

For a smooth departure from ORD, consider taking the “L” train to avoid Chicago traffic delays, especially during peak hours.

Read more about ORDby Ramsey Qubein
PTY

Upon arrival at PTY, use authorized taxis like Cooperativa de Transporte Taxi Expreso Tocumen R.L. for a reliable ride to Panama City.

Read more about PTYby Taryn White
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on ORD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Taryn White

Taryn White

Expert on PTY

Taryn White

Taryn White

Taryn White is a freelance travel writer, digital creator, and travel advisor who has visited nearly 100 countries and all 50 states. She’s familiar with many airports and enjoys beach hopping, boutique hotels, spa experiences, and exploring local culture. Her work has appeared in Travel + Leisure, Condé Nast Traveler, National Geographic, Smithsonian Magazine, AFAR, and more.

Read more

Best time to book a flight from Chicago to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Panama City

How far ahead should I book a flight from Chicago to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Panama City. Price data was last updated on September 12, 2025.

The price you pay for your flight from Chicago to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago to Panama City?

Currently, October is the cheapest month in which you can book a flight from Chicago to Panama City (average of $478). Flying from Chicago to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to PTY?

Find hourly flight availability from Chicago to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 17% on flights from Chicago to Panama City by exploring options for tickets in the evening.

What is the cheapest day to fly from Chicago to Panama City?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Panama City. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Chicago to Panama City flight should consider departing on Monday evenings when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to Panama City

Explore weekly flight availability from Chicago to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from CHI to PTY are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 15, 2025.
See what other customers who have flown with Delta, Copa Airlines, and United Airlines from Chicago to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.6
Good
1,531 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,929 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,435 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Chicago to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Chicago?

    Located just 11.4 mi from the city center, Panama City Tocumen Intl is the airport most travelers will use when flying to Panama City from Chicago. Booking flights from Chicago to Tocumen Intl (PTY) should be relatively easy as there are 3 daily inbound flights from Chicago from 5 different airlines.

  • How long is the flight from Chicago to Panama City?

    A quick flight from Chicago to Panama City can take about 5h 28m. Copa Airlines provides one of the quickest options available for as low as $451. There are 2330 mi between Chicago and Panama City. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Chicago to Panama City round-trip?

    Avianca, at $334, was found to be the cheapest airline from Chicago to Panama City.Alternate airlines to your destination round-trip include Copa Airlines and United Airlines. Users have found that Avianca is 41% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Chicago to Panama City?

    Consider EVA Air (92%), United Airlines (85%) or Copa Airlines (75%) when booking your flight. These represent the most reliable airlines when flying from Chicago to Panama City.

  • What are the cheapest flights from Chicago to Panama City?

    The cheapest flight price from Chicago to Panama City is $133. On average you can expect to pay $700. The most popular route, (Chicago O'Hare Intl - Panama City Tocumen Intl), can usually be booked for $359.

  • Can I find deals for flights from Chicago to Panama City that include hotel bookings?

    Yes. In addition to deals on Chicago to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Panama City.

  • Can I find deals for business class flights from Chicago to Panama City?

    Yes. Cheapflights offers flight deals from Chicago to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Chicago to Panama City (average of $478). Flying from Chicago to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Chicago to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Panama City flights
Midway to Panama City flights
Evansville to Panama City flights
St. Louis to Panama City flights
O'Hare Intl to David flights

Top 5 airlines flying from Chicago to Panama City

Discover the top 5 airlines that operate flights from Chicago to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$334Average$457FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$464Average$583FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$478Average$653FlexibilityNo cancel feeOn-time69%
DeltaCheapest$479Average$653FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$563Average$707FlexibilityNo cancel feeOn-time71%

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