$332+ Cheap flights from Chicago (CHI) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — PTY
Sep 5 — Sep 121
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to PanamaExplore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
Explore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 6, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:20 pm -
1 stop16h 25m
Sun 9/209:50 am -
1 stop15h 12m
Deal found 8/1![Copa Airlines logo]()
$540
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:35 am -
1 stop30h 30m
Wed 8/266:36 pm -
1 stop28h 51m
Deal found 7/31![Multiple Airlines logo]()
$648
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:35 am -
1 stop30h 30m
Tue 8/256:36 pm -
2 stops42h 14m
Deal found 8/1![Multiple Airlines logo]()
$659
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:20 am -
3 stops26h 55m
Mon 9/284:25 am -
3 stops31h 26m
Deal found 8/3![Multiple Airlines logo]()
$676
This Trip.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:20 am -
3 stops18h 15m
Mon 10/54:25 am -
3 stops31h 26m
Deal found 7/31![Multiple Airlines logo]()
$679
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:05 am -
3 stops27h 10m
Mon 9/73:10 pm -
3 stops31h 37m
Deal found 8/4![Multiple Airlines logo]()
$680
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:20 am -
3 stops26h 55m
Tue 9/2910:10 am -
3 stops25h 41m
Deal found 8/4![Multiple Airlines logo]()
$688
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:05 am -
3 stops27h 10m
Tue 9/84:25 am -
3 stops18h 22m
Deal found 8/4![Multiple Airlines logo]()
$692
This Mytrip deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/81:40 am -
3 stops31h 35m
Sat 9/125:55 pm -
3 stops35h 57m
Deal found 8/4![Multiple Airlines logo]()
$695
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:05 am -
3 stops26h 10m
Mon 9/75:30 am -
3 stops38h 38m
Deal found 8/4![Multiple Airlines logo]()
$697
This Trip.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:05 am -
3 stops26h 10m
Mon 9/75:30 am -
3 stops38h 38m
Deal found 8/1![Multiple Airlines logo]()
$699
This Mytrip deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/201:40 am -
3 stops24h 15m
Mon 9/285:30 am -
3 stops24h 22m
Deal found 8/4![Multiple Airlines logo]()
$702
Best flights from Chicago to PanamaDiscover carefully curated flight deals from Chicago to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
Discover carefully curated flight deals from Chicago to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 6, 2026.
This Copa Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/163:20 pm -
1 stop25h 05m
Wed 9/239:50 am -
1 stop15h 12m
Deal found 8/2![Copa Airlines logo]()
$540
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/2410:42 am -
1 stop7h 56m
Sun 1/314:41 pm -
1 stop16h 06m
Deal found 8/3![United Airlines logo]()
$792
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 05m
Wed 12/93:30 pm -
1 stop8h 26m
Deal found 8/2![Delta logo]()
$792
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:20 pm -
1 stop16h 25m
Sun 9/209:50 am -
1 stop15h 12m
Deal found 8/1![Copa Airlines logo]()
$540
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop7h 05m
Mon 11/233:30 pm -
1 stop8h 26m
Deal found 8/3![Delta logo]()
$792
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:30 am -
1 stop12h 01m
Sun 10/119:45 am -
1 stop10h 23m
Deal found 8/4![United Airlines logo]()
$800
This Copa Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/157:35 am -
Nonstop5h 26m
Mon 1/188:08 am -
Nonstop5h 38m
Deal found 8/2![Copa Airlines logo]()
$777
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:04 am -
1 stop6h 55m
Tue 10/272:24 pm -
1 stop8h 09m
Deal found 8/1![Delta logo]()
$794
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop13h 31m
Tue 10/610:00 am -
1 stop13h 27m
Deal found 8/2![United Airlines logo]()
$800
This Copa Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:35 am -
Nonstop5h 26m
Tue 11/107:28 pm -
Nonstop5h 43m
Deal found 8/2![Copa Airlines logo]()
$777
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:27 am -
1 stop7h 32m
Tue 11/103:30 pm -
2 stops17h 16m
Deal found 8/4![Delta logo]()
$796
This Copa Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:01 am -
Nonstop5h 21m
Sun 10/118:10 am -
Nonstop5h 49m
Deal found 8/2![Copa Airlines logo]()
$785
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:04 am -
1 stop6h 55m
Tue 10/272:24 pm -
1 stop8h 09m
Deal found 8/4![Delta logo]()
$800
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:01 am -
Nonstop5h 21m
Mon 10/57:20 pm -
Nonstop5h 37m
Deal found 7/31![Copa Airlines logo]()
$785
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:04 am -
1 stop6h 55m
Fri 10/232:24 pm -
1 stop8h 09m
Deal found 8/4![Delta logo]()
$800
This Copa Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:01 am -
Nonstop5h 21m
Tue 9/297:25 pm -
Nonstop5h 37m
Deal found 8/3![Copa Airlines logo]()
$785
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:04 am -
1 stop6h 55m
Thu 10/152:24 pm -
1 stop8h 09m
Deal found 8/3![Delta logo]()
$800
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:01 am -
Nonstop5h 21m
Mon 10/127:20 pm -
Nonstop5h 37m
Deal found 8/1![Copa Airlines logo]()
$785
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:05 am -
1 stop6h 53m
Mon 10/52:23 pm -
1 stop8h 21m
Deal found 7/31![Delta logo]()
$800
This Copa Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:13 pm -
Nonstop5h 24m
Sun 11/158:05 am -
Nonstop5h 41m
Deal found 8/4![Copa Airlines logo]()
$797
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/239:25 am -
2 stops22h 22m
Tue 1/269:48 am -
2 stops36h 59m
Deal found 8/2![United Airlines logo]()
$1,284
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:05 am -
1 stop6h 53m
Wed 9/232:23 pm -
1 stop8h 21m
Deal found 8/2![Delta logo]()
$800
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:04 am -
1 stop6h 55m
Sat 10/172:24 pm -
1 stop8h 09m
Deal found 8/5![Delta logo]()
$820
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:35 am -
1 stop24h 13m
Sun 1/107:55 pm -
1 stop17h 51m
Deal found 8/1![Copa Airlines logo]()
$856
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:45 am -
2 stops24h 03m
Sun 1/109:48 am -
2 stops15h 27m
Deal found 8/4![United Airlines logo]()
$1,605
Last-minute flights from Chicago to PanamaDiscover last-minute flight deals from Chicago to Panama. Data last updated August 6, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Panama. Data last updated August 6, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:35 am -
1 stop30h 30m
Tue 8/256:36 pm -
2 stops42h 14m
Deal found 8/1![Multiple Airlines logo]()
$659
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:35 am -
1 stop30h 30m
Wed 8/266:36 pm -
1 stop28h 51m
Deal found 7/31![Multiple Airlines logo]()
$648
This Trip.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:05 am -
3 stops26h 10m
Mon 9/75:30 am -
3 stops38h 38m
Deal found 8/1![Multiple Airlines logo]()
$699
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:05 am -
3 stops27h 10m
Tue 9/84:25 am -
3 stops18h 22m
Deal found 8/4![Multiple Airlines logo]()
$692
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:05 am -
3 stops27h 10m
Mon 9/73:10 pm -
3 stops31h 37m
Deal found 8/4![Multiple Airlines logo]()
$680
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:05 am -
3 stops26h 10m
Mon 9/75:30 am -
3 stops38h 38m
Deal found 8/4![Multiple Airlines logo]()
$697
This Copa Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:20 pm -
1 stop16h 25m
Sun 9/209:50 am -
1 stop15h 12m
Deal found 8/1![Copa Airlines logo]()
$540
This Mytrip deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/81:40 am -
3 stops31h 35m
Sat 9/125:55 pm -
3 stops35h 57m
Deal found 8/4![Multiple Airlines logo]()
$695
This Mytrip deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:40 am -
3 stops31h 35m
Wed 9/235:30 am -
3 stops24h 22m
Deal found 8/2![Multiple Airlines logo]()
$703
This Mytrip deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/201:40 am -
3 stops24h 15m
Mon 9/285:30 am -
3 stops24h 22m
Deal found 8/4![Multiple Airlines logo]()
$702
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:20 am -
3 stops26h 55m
Mon 9/284:25 am -
3 stops31h 26m
Deal found 8/3![Multiple Airlines logo]()
$676
This Trip.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:20 am -
3 stops26h 55m
Tue 9/2910:10 am -
3 stops25h 41m
Deal found 8/4![Multiple Airlines logo]()
$688
One-way flights from Chicago to PanamaSearch for one-way flight options from Chicago to Panama. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
Search for one-way flight options from Chicago to Panama. Find affordable one-way fares based on user searches. Data last updated August 6, 2026.
This Mytrip deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:40 am -
3 stops24h 15m
Deal found 8/3![Multiple Airlines logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:20 am -
2 stops23h 10m
Deal found 8/4![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:03 pm -
2 stops20h 27m
Deal found 8/4![Multiple Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:50 am -
2 stops24h 59m
Deal found 8/5![Multiple Airlines logo]()
$341
This Mytrip deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:40 am -
3 stops24h 15m
Deal found 8/3![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:03 pm -
2 stops20h 27m
Deal found 8/5![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/112:53 am -
2 stops27h 08m
Deal found 8/5![Multiple Airlines logo]()
$361
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:35 am -
1 stop22h 26m
Deal found 8/5![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:40 am -
2 stops25h 26m
Deal found 8/5![Multiple Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:00 am -
3 stops49h 00m
Deal found 8/5![Multiple Airlines logo]()
$410
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:46 pm -
2 stops25h 51m
Deal found 8/4![Multiple Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:49 pm -
2 stops33h 12m
Deal found 8/5![Multiple Airlines logo]()
$426
Find flight deals from Chicago to Panama
Keep the following information in mind while searching for Chicago to Panama flight deals. Data was last updated August 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $540 (Copa Airlines) |
One-way from | $332 (Mytrip) |
Popular in | July |
Cheapest in | February |
Average price | $753 |
Good round-trip deal | $523 or less |
Good one-way deal | $290 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Chicago to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoDavid
ORD Chicago O'Hare Intl - DAV David Enrique Malek
ORDDAV
Chicago O'Hare Intl
Wed 9/16
3:20 pm-4:25 pm
1 stop25h 05m
David Enrique Malek
Wed 9/23
9:50 am-1:02 am
1 stop15h 12m
$540
ChicagoDavid
ORD Chicago O'Hare Intl - DAV David Enrique Malek
ORDDAV
Chicago O'Hare Intl
Sun 9/6
3:20 pm-7:45 am
1 stop16h 25m
David Enrique Malek
Sun 9/20
9:50 am-1:02 am
1 stop15h 12m
$540
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Fri 1/15
7:35 am-2:01 pm
Nonstop5h 26m
Panama City Tocumen Intl
Mon 1/18
8:08 am-12:46 pm
Nonstop5h 38m
$777
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 11/5
7:35 am-2:01 pm
Nonstop5h 26m
Panama City Tocumen Intl
Tue 11/10
7:28 pm-12:11 am
Nonstop5h 43m
$777
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 10/8
8:01 am-1:22 pm
Nonstop5h 21m
Panama City Tocumen Intl
Sun 10/11
8:10 am-1:59 pm
Nonstop5h 49m
$785
Quickest round-trip
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 10/1
8:01 am-1:22 pm
Nonstop5h 21m
Panama City Tocumen Intl
Mon 10/5
7:20 pm-12:57 am
Nonstop5h 37m
$785
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 9/24
8:01 am-1:22 pm
Nonstop5h 21m
Panama City Tocumen Intl
Tue 9/29
7:25 pm-1:02 am
Nonstop5h 37m
$785
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Fri 10/9
8:01 am-1:22 pm
Nonstop5h 21m
Panama City Tocumen Intl
Mon 10/12
7:20 pm-12:57 am
Nonstop5h 37m
$785
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Sun 1/24
10:42 am-7:38 pm
1 stop7h 56m
Panama City Tocumen Intl
Sun 1/31
4:41 pm-7:47 am
1 stop16h 06m
$792
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Wed 11/18
6:00 am-2:05 pm
1 stop7h 05m
Panama City Tocumen Intl
Wed 12/9
3:30 pm-10:56 pm
1 stop8h 26m
$792
Showing 1-10 of 54 resultsSorted by cheapest first
Best time to book a flight from Chicago to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Chicago with our price prediction graph.
ORD-DAV
ORD-PTY
MDW-PTY
ORD-PAC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Panama
CHI-PA0
ORD-DAV
ORD-PTY
MDW-PTY
ORD-PAC
What is the cheapest month to book a flight from Chicago to Panama?
Currently, April is the cheapest month in which you can book a flight from Chicago to Panama (average of $584). Flying from Chicago to Panama in July is currently the most expensive (average of $777). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to PA?
Find hourly flight availability from Chicago to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 6, 2026.
One of the essential ways to save on airfare from Chicago to Panama is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 18% on airfare.
Weekly flight availability from Chicago to Panama
Explore weekly flight availability from Chicago to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 6, 2026.
The most flights from CHI to PA0 are scheduled on a Monday (5 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (2 on average).
How often are flights from Chicago to Panama delayed?
About 12% of weekly flights between Chicago and Panama have experienced delays in the past year, with the average delay time being 122 minutes.
What is the most punctual flight time for Chicago to Panama flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Chicago to Panama flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 12% of flights being delayed.
How far ahead should I book a flight from Chicago to Panama?
The best time to book flights from Chicago to Panama is 48 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Chicago to Panama?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Panama. Price data was last updated on August 1, 2026.
Travelers seeking maximum savings on their Chicago to Panama flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 6, 2026.
See what other customers who have flown with Copa Airlines,United Airlines, andAmerican Airlines from Chicago to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Entertainment
6.8
Food
6.9
Overall
7.6
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Boarding
7.8
Entertainment
6.8
Food
6.9
Overall
7.6
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Boarding
7.8
Entertainment
6.8
Food
6.9
Overall
7.6
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Boarding
7.8
Entertainment
6.8
Food
6.9
Overall
7.6
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Boarding
7.8
Entertainment
6.8
Food
6.9
Overall
7.6
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Panama
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Complete your trip
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Search flights from Chicago to Panama by cabin class
Find flights from Chicago to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Panama flights
Browse other Chicago and Panama flight options. Last updated on August 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Chicago to Panama
Discover the top 4 airlines that operate flights from Chicago to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$302 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$450 | Average$617 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$577 | Average$764 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$601 | Average$788 | FlexibilityNo cancel fee | On-time71% |