$311+ Cheap flights from Chicago (CHI) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — PTY
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Cheapest flights from Chicago to PanamaExplore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This Avianca deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:30 pm -
1 stop17h 45m
Thu 12/32:30 am -
1 stop19h 00m
Deal found 10/31![Avianca logo]()
$729
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 34m
Fri 12/43:13 pm -
1 stop17h 42m
Deal found 11/1![American Airlines logo]()
$757
This Avianca deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:30 pm -
1 stop9h 40m
Sun 11/222:30 am -
1 stop19h 00m
Deal found 10/31![Avianca logo]()
$764
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:00 am -
1 stop8h 13m
Wed 1/272:26 pm -
1 stop11h 39m
Deal found 11/2![American Airlines logo]()
$768
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:50 pm -
1 stop17h 23m
Wed 11/113:13 pm -
1 stop10h 31m
Deal found 11/2![American Airlines logo]()
$777
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:50 pm -
1 stop17h 23m
Tue 11/103:13 pm -
2 stops17h 13m
Deal found 11/3![American Airlines logo]()
$782
This FlightHub deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3010:30 pm -
1 stop25h 50m
Tue 3/1610:05 am -
1 stop11h 25m
Deal found 10/31![Avianca logo]()
$786
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 13m
Wed 12/93:13 pm -
2 stops17h 17m
Deal found 11/3![American Airlines logo]()
$787
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:50 pm -
1 stop17h 23m
Mon 11/93:13 pm -
1 stop10h 31m
Deal found 11/2![American Airlines logo]()
$791
This Copa Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/62:17 pm -
1 stop16h 30m
Sun 1/108:47 am -
1 stop16h 20m
Deal found 11/1![Copa Airlines logo]()
$852
This oojo deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:17 pm -
1 stop16h 30m
Sat 1/97:55 pm -
1 stop29h 12m
Deal found 11/2![Copa Airlines logo]()
$855
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop7h 04m
Fri 12/113:29 pm -
1 stop8h 25m
Deal found 11/2![Delta logo]()
$868
Best flights from Chicago to PanamaDiscover carefully curated flight deals from Chicago to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Chicago to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/62:13 pm -
Nonstop5h 23m
Sun 3/147:55 am -
Nonstop5h 39m
Deal found 11/4![Copa Airlines logo]()
$777
This Avianca deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:30 pm -
1 stop9h 40m
Sun 11/222:30 am -
1 stop19h 00m
Deal found 11/4![Avianca logo]()
$799
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/510:30 am -
1 stop8h 32m
Fri 2/198:55 am -
1 stop10h 11m
Deal found 11/2![United Airlines logo]()
$812
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:00 am -
1 stop7h 04m
Wed 2/243:20 pm -
1 stop8h 25m
Deal found 11/2![Delta logo]()
$812
This FlightHub deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2611:30 pm -
2 stops19h 51m
Sun 4/48:10 pm -
2 stops25h 10m
Deal found 10/31![Multiple Airlines logo]()
$1,507
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/122:13 pm -
Nonstop5h 25m
Mon 1/188:08 am -
Nonstop5h 38m
Deal found 11/3![Copa Airlines logo]()
$805
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/51:41 pm -
2 stops21h 40m
Wed 2/243:20 pm -
1 stop8h 25m
Deal found 11/2![Delta logo]()
$817
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/207:10 am -
1 stop11h 52m
Fri 3/263:41 pm -
1 stop16h 08m
Deal found 10/31![United Airlines logo]()
$860
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/92:13 pm -
Nonstop5h 23m
Mon 2/157:28 pm -
Nonstop5h 43m
Deal found 11/3![Copa Airlines logo]()
$805
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:30 am -
1 stop15h 21m
Sat 1/98:00 am -
1 stop9h 15m
Deal found 11/2![Delta logo]()
$820
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/217:10 am -
1 stop11h 52m
Sat 3/279:30 am -
1 stop14h 28m
Deal found 10/31![United Airlines logo]()
$860
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/17:35 am -
Nonstop5h 19m
Mon 3/87:04 pm -
Nonstop5h 40m
Deal found 11/3![Copa Airlines logo]()
$805
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/176:00 am -
1 stop6h 55m
Wed 2/243:20 pm -
1 stop8h 25m
Deal found 11/5![Delta logo]()
$832
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/152:13 pm -
Nonstop5h 25m
Mon 1/188:08 am -
Nonstop5h 38m
Deal found 11/3![Copa Airlines logo]()
$805
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop7h 03m
Sun 12/63:29 pm -
1 stop8h 25m
Deal found 11/1![Delta logo]()
$868
This Copa Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/272:13 pm -
Nonstop5h 25m
Wed 3/107:04 pm -
Nonstop5h 40m
Deal found 11/1![Copa Airlines logo]()
$829
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop7h 04m
Mon 12/73:29 pm -
1 stop8h 25m
Deal found 11/1![Delta logo]()
$868
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/177:35 am -
Nonstop5h 24m
Wed 2/247:28 pm -
Nonstop5h 43m
Deal found 11/4![Copa Airlines logo]()
$853
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop7h 04m
Sun 12/133:29 pm -
1 stop8h 25m
Deal found 11/2![Delta logo]()
$868
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:25 am -
2 stops24h 24m
Mon 2/89:47 am -
2 stops35h 21m
Deal found 11/3![United Airlines logo]()
$1,257
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop7h 03m
Sat 12/123:29 pm -
1 stop8h 25m
Deal found 11/1![Delta logo]()
$868
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2611:30 pm -
2 stops19h 51m
Sat 4/38:10 pm -
2 stops25h 10m
Deal found 11/4![Multiple Airlines logo]()
$1,573
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/219:18 am -
2 stops22h 29m
Mon 1/259:48 am -
2 stops35h 20m
Deal found 11/1![United Airlines logo]()
$1,265
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop7h 04m
Fri 12/113:29 pm -
2 stops22h 32m
Deal found 11/2![Delta logo]()
$873
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:00 am -
1 stop7h 04m
Mon 2/223:20 pm -
1 stop19h 45m
Deal found 11/2![Delta logo]()
$889
This Copa Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/263:13 pm -
1 stop17h 19m
Sun 4/48:10 pm -
1 stop17h 24m
Deal found 10/31![Copa Airlines logo]()
$1,153
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:44 pm -
2 stops18h 18m
Fri 11/273:29 pm -
2 stops19h 17m
Deal found 11/1![Delta logo]()
$944
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:44 pm -
2 stops18h 18m
Thu 11/263:29 pm -
2 stops20h 56m
Deal found 11/1![Delta logo]()
$944
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:00 am -
1 stop7h 03m
Sun 2/143:20 pm -
1 stop8h 25m
Deal found 11/5![Delta logo]()
$959
Last-minute flights from Chicago to PanamaDiscover last-minute flight deals from Chicago to Panama. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Panama. Data last updated November 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:50 pm -
1 stop17h 23m
Wed 11/113:13 pm -
1 stop10h 31m
Deal found 11/2![American Airlines logo]()
$777
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:50 pm -
1 stop17h 23m
Tue 11/103:13 pm -
2 stops17h 13m
Deal found 11/3![American Airlines logo]()
$782
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 13m
Wed 12/93:13 pm -
2 stops17h 17m
Deal found 11/3![American Airlines logo]()
$787
This Avianca deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:30 pm -
1 stop9h 40m
Sun 11/222:30 am -
1 stop19h 00m
Deal found 10/31![Avianca logo]()
$764
This Avianca deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:30 pm -
1 stop17h 45m
Thu 12/32:30 am -
1 stop19h 00m
Deal found 10/31![Avianca logo]()
$729
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 34m
Fri 12/43:13 pm -
1 stop17h 42m
Deal found 11/1![American Airlines logo]()
$757
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:50 pm -
1 stop17h 44m
Mon 12/73:13 pm -
1 stop17h 47m
Deal found 11/1![American Airlines logo]()
$791
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:00 am -
1 stop7h 04m
Sat 12/123:29 pm -
1 stop8h 25m
Deal found 11/2![Delta logo]()
$868
This oojo deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:17 pm -
1 stop16h 30m
Sat 1/97:55 pm -
1 stop29h 12m
Deal found 11/2![Copa Airlines logo]()
$855
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:00 am -
1 stop8h 13m
Wed 1/272:26 pm -
1 stop11h 39m
Deal found 11/2![American Airlines logo]()
$768
This Copa Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/62:17 pm -
1 stop16h 30m
Sun 1/108:47 am -
1 stop16h 20m
Deal found 11/1![Copa Airlines logo]()
$852
This FlightHub deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3010:30 pm -
1 stop25h 50m
Tue 3/1610:05 am -
1 stop11h 25m
Deal found 10/31![Avianca logo]()
$786
One-way flights from Chicago to PanamaSearch for one-way flight options from Chicago to Panama. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Chicago to Panama. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/285:59 pm -
1 stop18h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/135:59 pm -
1 stop18h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/245:59 pm -
1 stop18h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/28:29 pm -
1 stop18h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/251:44 pm -
2 stops22h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/232:52 pm -
2 stops21h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:00 am -
2 stops26h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/258:25 am -
3 stops39h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$394
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/146:00 am -
2 stops10h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Multiple Airlines logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/281:18 pm -
2 stops17h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/105:21 pm -
2 stops26h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$408
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:40 am -
2 stops26h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Multiple Airlines logo]()
$475
Find flight deals from Chicago to Panama
Keep the following information in mind while searching for Chicago to Panama flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $704 (American Airlines) |
One-way from | $311 (American Airlines) |
Popular in | December |
Cheapest in | May |
Average price | $793 |
Good round-trip deal | $599 or less |
Good one-way deal | $295 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Chicago to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Sat 3/6
9:45 pm-1:25 pm
2 stops14h 40m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$340
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 1/14
6:00 am-5:17 pm
2 stops10h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$395
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Thu 1/28
1:18 pm-7:49 am
2 stops17h 31m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$402
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Sun 1/10
5:21 pm-8:29 pm
3 stops26h 08m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$417
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Sat 12/5
10:40 am-1:46 pm
2 stops26h 06m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$475
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Wed 12/23
8:35 pm-8:24 pm
2 stops22h 49m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$482
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 1/14
2:38 pm-1:26 pm
1 stop21h 48m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$489
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Sat 11/14
7:15 am-8:19 pm
2 stops12h 04m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$490
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Sun 3/7
1:18 pm-8:03 pm
1 stop29h 45m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$526
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Sat 3/6
1:18 pm-4:50 am
2 stops14h 32m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$551
Showing 1-10 of 53 resultsSorted by cheapest first
Best time to book a flight from Chicago to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Chicago with our price prediction graph.
ORD-PTY
MDW-PTY
ORD-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Panama
CHI-PA0
ORD-PTY
MDW-PTY
ORD-DAV
What is the cheapest month to book a flight from Chicago to Panama?
Currently, April is the cheapest month in which you can book a flight from Chicago to Panama (average of $584). Flying from Chicago to Panama in December is currently the most expensive (average of $1,064). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to PA?
Find hourly flight availability from Chicago to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2026.
One of the essential ways to save on airfare from Chicago to Panama is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 14% on airfare.
How often are flights from Chicago to Panama delayed?
About 13% of weekly flights between Chicago and Panama have experienced delays in the past year, with the average delay time being 121 minutes.
What is the most punctual flight time for Chicago to Panama flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Chicago to Panama flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 12% of flights being delayed.
How far ahead should I book a flight from Chicago to Panama?
The best time to book flights from Chicago to Panama is 75 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Chicago to Panama?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Panama. Price data was last updated on October 31, 2026.
Travelers seeking maximum savings on their Chicago to Panama flight should consider departing on Thursday evenings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 5, 2026.
See what other customers who have flown with Delta,Copa Airlines, andUnited Airlines from Chicago to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Chicago to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Panama by cabin class
Find flights from Chicago to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Panama flights
Browse other Chicago and Panama flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Chicago to Panama
Discover the top 4 airlines that operate flights from Chicago to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$376 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$563 | Average$700 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$586 | Average$814 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$596 | Average$805 | FlexibilityNo cancel fee | On-time71% |