$308+ Cheap flights from Chicago (CHI) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — PTY
Jun 6 — Jun 131
Round-trip
1 adult, Economy
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Cheapest flights from Chicago to PanamaExplore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
Explore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 7, 2026.
This FlipMilhas deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlipMilhas is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/131:00 am
ORD
- PTY
Nonstop5h 20m
GOL
Fri 6/1911:30 am
PTY
- ORD
Nonstop5h 56m
GOL
Deal found 5/4![GOL logo]()
$470
This Copa Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:01 am
ORD
- DAV
1 stop11h 16m
Copa Airlines
Tue 10/137:57 pm
DAV
- ORD
1 stop18h 02m
Copa Airlines
Deal found 5/4![Copa Airlines logo]()
$614
This Copa Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/303:21 pm
ORD
- DAV
1 stop17h 42m
Copa Airlines
Sun 8/99:50 am
DAV
- ORD
1 stop15h 12m
Copa Airlines
Deal found 5/6![Copa Airlines logo]()
$633
This Trip.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:00 am
MDW
- PTY
3 stops18h 35m
Multiple Airlines
Mon 6/83:10 pm
PTY
- MDW
3 stops20h 02m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$637
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Fri 6/59:33 pm
PTY
- MDW
2 stops24h 29m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$658
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Mon 6/86:15 pm
PTY
- MDW
2 stops16h 57m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$672
This Vliegwinkel deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Vliegwinkel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2211:20 pm
ORD
- PTY
1 stop17h 40m
Avianca
Sun 6/2810:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Deal found 5/4![Avianca logo]()
$678
This Gotogate deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:15 pm
ORD
- PTY
1 stop8h 40m
Avianca
Mon 6/810:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Deal found 5/3![Avianca logo]()
$682
This Gotogate deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:20 pm
ORD
- PTY
1 stop9h 55m
Avianca
Mon 6/84:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Deal found 5/3![Avianca logo]()
$684
This Gotogate deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:20 pm
ORD
- PTY
1 stop9h 30m
Avianca
Tue 3/169:45 am
PTY
- ORD
1 stop11h 35m
Avianca
Deal found 5/5![Avianca logo]()
$686
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Mon 6/89:33 pm
PTY
- MDW
2 stops13h 39m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$687
This Copa Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:01 am
ORD
- PTY
Nonstop5h 21m
Copa Airlines
Mon 10/127:20 pm
PTY
- ORD
Nonstop5h 37m
Copa Airlines
Deal found 5/4![Copa Airlines logo]()
$687
Best flights from Chicago to PanamaDiscover carefully curated flight deals from Chicago to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
Discover carefully curated flight deals from Chicago to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 7, 2026.
This Copa Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:21 pm
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Tue 7/76:25 pm
PTY
- ORD
Nonstop5h 36m
Copa Airlines
Deal found 5/3![Copa Airlines logo]()
$695
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am
MDW
- PTY
1 stop7h 13m
Delta
Sun 9/132:21 pm
PTY
- MDW
2 stops22h 09m
Delta
Deal found 5/4![Delta logo]()
$706
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:30 am
ORD
- PTY
1 stop13h 07m
United Airlines
Sat 7/253:30 pm
PTY
- ORD
1 stop9h 15m
United Airlines
Deal found 5/4![United Airlines logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:27 pm
MDW
- PTY
1 stop8h 07m
Multiple Airlines
Sat 6/139:45 pm
PTY
- MDW
2 stops41h 30m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$853
This Copa Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:02 am
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Tue 7/146:25 pm
PTY
- ORD
Nonstop5h 36m
Copa Airlines
Deal found 5/6![Copa Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/69:40 pm
ORD
- PTY
1 stop16h 34m
United Airlines
Wed 7/153:30 pm
PTY
- ORD
1 stop9h 15m
United Airlines
Deal found 5/6![United Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:50 pm
MDW
- PTY
1 stop24h 19m
Delta
Sat 7/42:27 pm
PTY
- MDW
1 stop7h 50m
Delta
Deal found 5/4![Delta logo]()
$745
This Copa Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:02 am
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Wed 7/88:10 am
PTY
- ORD
Nonstop5h 47m
Copa Airlines
Deal found 5/7![Copa Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/249:40 pm
ORD
- PTY
1 stop18h 32m
United Airlines
Wed 7/2910:55 pm
PTY
- ORD
1 stop12h 09m
United Airlines
Deal found 5/4![United Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:00 am
MDW
- PTY
1 stop7h 09m
Delta
Sun 6/282:24 pm
PTY
- MDW
1 stop25h 16m
Delta
Deal found 5/4![Delta logo]()
$750
This Copa Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:02 am
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Mon 7/2010:10 pm
PTY
- ORD
Nonstop5h 50m
Copa Airlines
Deal found 5/6![Copa Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:35 am
ORD
- PTY
1 stop8h 37m
United Airlines
Mon 7/1310:00 am
PTY
- ORD
1 stop10h 05m
United Airlines
Deal found 5/4![United Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:00 am
MDW
- PTY
1 stop7h 09m
Delta
Thu 6/252:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Deal found 5/4![Delta logo]()
$758
This Copa Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/63:21 pm
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Wed 7/1510:10 pm
PTY
- ORD
Nonstop5h 50m
Copa Airlines
Deal found 5/6![Copa Airlines logo]()
$705
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:00 am
MDW
- PTY
1 stop7h 09m
Delta
Sat 6/202:27 pm
PTY
- MDW
1 stop7h 50m
Delta
Deal found 5/3![Delta logo]()
$758
This Copa Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/43:21 pm
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Mon 7/1310:10 pm
PTY
- ORD
Nonstop5h 50m
Copa Airlines
Deal found 5/6![Copa Airlines logo]()
$705
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
MDW
- PTY
1 stop7h 09m
Delta
Mon 6/222:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Deal found 5/4![Delta logo]()
$758
This Copa Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/113:21 pm
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Tue 7/216:25 pm
PTY
- ORD
Nonstop5h 36m
Copa Airlines
Deal found 5/4![Copa Airlines logo]()
$705
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:36 pm
MDW
- PTY
2 stops18h 33m
Delta
Wed 6/102:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Deal found 5/5![Delta logo]()
$762
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:22 am
MDW
- PTY
2 stops27h 28m
Delta
Wed 6/102:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Deal found 5/1![Delta logo]()
$762
This Copa Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:02 am
ORD
- DAV
1 stop11h 12m
Copa Airlines
Mon 6/87:54 pm
DAV
- ORD
1 stop8h 06m
Copa Airlines
Deal found 5/4![Copa Airlines logo]()
$817
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:08 pm
MDW
- PTY
1 stop19h 42m
Delta
Mon 6/82:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Deal found 5/1![Delta logo]()
$769
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am
ORD
- DAV
2 stops26h 05m
United Airlines
Tue 11/109:50 am
DAV
- ORD
2 stops38h 52m
United Airlines
Deal found 5/4![United Airlines logo]()
$1,137
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:45 am
ORD
- DAV
2 stops25h 25m
United Airlines
Tue 9/299:50 am
DAV
- ORD
2 stops37h 40m
United Airlines
Deal found 5/2![United Airlines logo]()
$1,137
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
MDW
- PTY
1 stop7h 09m
Delta
Tue 7/72:24 pm
PTY
- MDW
1 stop7h 51m
Delta
Deal found 5/5![Delta logo]()
$819
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:30 pm
ORD
- DAV
2 stops35h 40m
United Airlines
Thu 9/179:50 am
DAV
- ORD
2 stops14h 58m
United Airlines
Deal found 5/5![United Airlines logo]()
$1,137
This Copa Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:01 am
ORD
- DAV
1 stop25h 09m
Copa Airlines
Tue 10/207:57 pm
DAV
- ORD
1 stop18h 02m
Copa Airlines
Deal found 5/4![Copa Airlines logo]()
$987
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:30 pm
ORD
- DAV
2 stops19h 33m
United Airlines
Sun 6/149:50 am
DAV
- ORD
2 stops14h 55m
United Airlines
Deal found 5/6![United Airlines logo]()
$1,193
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:00 am
ORD
- DAV
2 stops28h 03m
United Airlines
Mon 6/89:50 am
DAV
- ORD
2 stops24h 30m
United Airlines
Deal found 5/4![United Airlines logo]()
$1,193
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:30 am
ORD
- DAV
2 stops25h 28m
United Airlines
Tue 5/269:38 am
DAV
- ORD
2 stops37h 52m
United Airlines
Deal found 5/5![United Airlines logo]()
$1,273
Last-minute flights from Chicago to PanamaDiscover last-minute flight deals from Chicago to Panama. Data last updated May 7, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Panama. Data last updated May 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Mon 6/86:15 pm
PTY
- MDW
2 stops16h 57m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$672
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Fri 6/59:33 pm
PTY
- MDW
2 stops24h 29m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$658
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Mon 6/89:33 pm
PTY
- MDW
2 stops13h 39m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$687
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:04 pm
MDW
- PTY
1 stop8h 30m
Multiple Airlines
Mon 6/89:33 pm
PTY
- MDW
2 stops13h 39m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$691
This Avianca deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:20 pm
ORD
- PTY
1 stop17h 40m
Avianca
Fri 6/124:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Deal found 5/5![Avianca logo]()
$688
This Gotogate deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:20 pm
ORD
- PTY
1 stop9h 55m
Avianca
Mon 6/84:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Deal found 5/3![Avianca logo]()
$684
This Trip.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:00 am
MDW
- PTY
3 stops18h 35m
Multiple Airlines
Mon 6/83:10 pm
PTY
- MDW
3 stops20h 02m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$637
This Gotogate deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:15 pm
ORD
- PTY
1 stop8h 40m
Avianca
Mon 6/810:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Deal found 5/3![Avianca logo]()
$682
This FlipMilhas deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlipMilhas is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/131:00 am
ORD
- PTY
Nonstop5h 20m
GOL
Fri 6/1911:30 am
PTY
- ORD
Nonstop5h 56m
GOL
Deal found 5/4![GOL logo]()
$470
This Avianca deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/1411:20 pm
ORD
- PTY
1 stop14h 55m
Avianca
Fri 6/194:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Deal found 5/4![Avianca logo]()
$687
This Vliegwinkel deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Vliegwinkel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2211:20 pm
ORD
- PTY
1 stop17h 40m
Avianca
Sun 6/2810:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Deal found 5/4![Avianca logo]()
$678
This Avianca deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:15 pm
ORD
- PTY
1 stop8h 40m
Avianca
Fri 7/1710:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Deal found 5/6![Avianca logo]()
$690
One-way flights from Chicago to PanamaSearch for one-way flight options from Chicago to Panama. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
Search for one-way flight options from Chicago to Panama. Find affordable one-way fares based on user searches. Data last updated May 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/261:50 pm
ORD
- PTY
2 stops18h 16m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:40 am
MDW
- PTY
2 stops25h 50m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:49 am
ORD
- PTY
2 stops31h 11m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:30 am
ORD
- PTY
2 stops19h 05m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:30 am
ORD
- PTY
2 stops27h 45m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:55 am
ORD
- PTY
1 stop13h 39m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:59 am
MDW
- PTY
2 stops13h 36m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3111:26 am
ORD
- PTY
2 stops21h 23m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:27 pm
MDW
- PTY
1 stop8h 07m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:10 am
ORD
- PTY
2 stops16h 25m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$367
Find flight deals from Chicago to Panama
Keep the following information in mind while searching for Chicago to Panama flight deals. Data was last updated May 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $470 (FlipMilhas) |
One-way from | $308 (Kiwi.com) |
Popular in | May |
Cheapest in | September |
Average price | $748 |
Good round-trip deal | $484 or less |
Good one-way deal | $198 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
Use the filters below to find and compare flights from Chicago to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Wed 7/1
3:21 pm-8:41 pm
Nonstop5h 20m
Panama City Tocumen Intl
Tue 7/7
6:25 pm-12:01 am
Nonstop5h 36m
$695
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Wed 7/1
8:02 am-1:22 pm
Nonstop5h 20m
Panama City Tocumen Intl
Tue 7/14
6:25 pm-12:01 am
Nonstop5h 36m
$705
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Wed 7/1
8:02 am-1:22 pm
Nonstop5h 20m
Panama City Tocumen Intl
Wed 7/8
8:10 am-1:57 pm
Nonstop5h 47m
$705
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Mon 7/20
8:02 am-1:22 pm
Nonstop5h 20m
Panama City Tocumen Intl
Mon 7/20
10:10 pm-4:00 am
Nonstop5h 50m
$705
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Mon 7/6
3:21 pm-8:41 pm
Nonstop5h 20m
Panama City Tocumen Intl
Wed 7/15
10:10 pm-4:00 am
Nonstop5h 50m
$705
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Sat 7/4
3:21 pm-8:41 pm
Nonstop5h 20m
Panama City Tocumen Intl
Mon 7/13
10:10 pm-4:00 am
Nonstop5h 50m
$705
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Sat 7/11
3:21 pm-8:41 pm
Nonstop5h 20m
Panama City Tocumen Intl
Tue 7/21
6:25 pm-12:01 am
Nonstop5h 36m
$705
ChicagoPanama City
MDW - PTY
MDWPTY
Chicago Midway
Mon 9/7
6:00 am-1:13 pm
1 stop7h 13m
Panama City Tocumen Intl
Sun 9/13
2:21 pm-12:30 pm
2 stops22h 09m
$706
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Sun 7/19
5:30 am-6:37 pm
1 stop13h 07m
Panama City Tocumen Intl
Sat 7/25
3:30 pm-12:45 am
1 stop9h 15m
$710
ChicagoPanama City
ORD - PTY
ORDPTY
Chicago O'Hare Intl
Mon 7/6
9:40 pm-2:14 pm
1 stop16h 34m
Panama City Tocumen Intl
Wed 7/15
3:30 pm-12:45 am
1 stop9h 15m
$710
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Chicago with our price prediction graph.
ORD-PTY
ORD-DAV
MDW-PTY
ORD-PAC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Panama
CHI-PA0
ORD-PTY
ORD-DAV
MDW-PTY
ORD-PAC
How far ahead should I book a flight from Chicago to Panama?
The best time to book flights from Chicago to Panama is 26 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Chicago to Panama?
Currently, February is the cheapest month in which you can book a flight from Chicago to Panama (average of $102). Flying from Chicago to Panama in September is currently the most expensive (average of $450). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to PA?
Find hourly flight availability from Chicago to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 7, 2026.
One of the essential ways to save on airfare from Chicago to Panama is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 20% on airfare.
What is the cheapest day to fly from Chicago to Panama?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Panama. Price data was last updated on May 2, 2026.
Travelers seeking maximum savings on their Chicago to Panama flight should consider departing on Monday evenings when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Chicago to Panama
Explore weekly flight availability from Chicago to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 7, 2026.
The most flights from CHI to PA0 are scheduled on a Tuesday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).
How often are flights from Chicago to Panama delayed?
About 11% of weekly flights between Chicago and Panama have experienced delays in the past year, with the average delay time being 127 minutes.
What is the most punctual flight time for Chicago to Panama flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Chicago to Panama flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 11% of flights being delayed.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 7, 2026.
See what other customers who have flown with Delta,Copa Airlines, andUnited Airlines from Chicago to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.9
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Chicago to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Chicago to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Panama by cabin class
Find flights from Chicago to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Panama flights
Browse other Chicago and Panama flight options. Last updated on May 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Chicago to Panama
Discover the top 4 airlines that operate flights from Chicago to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$302 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$450 | Average$749 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$479 | Average$653 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$601 | Average$721 | FlexibilityNo cancel fee | On-time71% |