$263+ Cheap flights from Chicago (CHI) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — PTY
Oct 24 — Oct 311
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to PanamaExplore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This Avianca deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:30 pm -
1 stop17h 45m
Tue 11/1010:05 am -
1 stop11h 25m
Deal found 9/20![Avianca logo]()
$592
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
1 stop7h 02m
Mon 11/233:29 pm -
1 stop8h 25m
Deal found 9/20![Delta logo]()
$607
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
1 stop13h 08m
Wed 11/258:55 am -
1 stop10h 34m
Deal found 9/20![United Airlines logo]()
$607
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2811:19 am -
2 stops25h 43m
Wed 12/23:29 pm -
2 stops17h 30m
Deal found 9/20![Delta logo]()
$611
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 13m
Wed 12/93:13 pm -
1 stop17h 29m
Deal found 9/21![American Airlines logo]()
$612
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 13m
Tue 11/243:34 pm -
2 stops16h 51m
Deal found 9/20![American Airlines logo]()
$616
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:50 pm -
1 stop19h 12m
Thu 12/33:29 pm -
2 stops17h 30m
Deal found 9/20![Delta logo]()
$621
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 34m
Fri 12/43:13 pm -
1 stop17h 47m
Deal found 9/22![American Airlines logo]()
$627
This Copa Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:35 am -
1 stop24h 15m
Thu 12/39:48 am -
1 stop15h 23m
Deal found 9/24![Copa Airlines logo]()
$630
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 34m
Wed 12/23:13 pm -
2 stops17h 14m
Deal found 9/22![American Airlines logo]()
$631
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:13 pm -
Nonstop5h 24m
Wed 11/258:05 am -
Nonstop5h 41m
Deal found 9/20![Copa Airlines logo]()
$640
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:35 am -
Nonstop5h 26m
Fri 11/278:05 am -
Nonstop5h 41m
Deal found 9/20![Copa Airlines logo]()
$649
Best flights from Chicago to PanamaDiscover carefully curated flight deals from Chicago to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Chicago to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/232:13 pm -
Nonstop5h 25m
Mon 2/17:28 pm -
Nonstop5h 43m
Deal found 9/20![Copa Airlines logo]()
$592
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
1 stop7h 02m
Mon 11/233:29 pm -
1 stop8h 25m
Deal found 9/20![Delta logo]()
$607
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:29 am -
1 stop11h 09m
Tue 11/248:55 am -
1 stop13h 45m
Deal found 9/20![United Airlines logo]()
$684
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:13 pm -
Nonstop5h 24m
Mon 11/237:28 pm -
Nonstop5h 43m
Deal found 9/20![Copa Airlines logo]()
$592
This FlightHub deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:20 pm -
2 stops17h 05m
Wed 10/287:57 pm -
2 stops25h 33m
Deal found 9/21![Multiple Airlines logo]()
$1,297
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 02m
Wed 12/93:29 pm -
1 stop8h 25m
Deal found 9/21![Delta logo]()
$711
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:20 pm -
1 stop21h 42m
Mon 1/184:41 pm -
1 stop9h 02m
Deal found 9/20![United Airlines logo]()
$772
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/127:35 am -
Nonstop5h 26m
Mon 1/187:28 pm -
Nonstop5h 39m
Deal found 9/22![Copa Airlines logo]()
$757
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:05 pm -
1 stop24h 02m
Thu 11/193:29 pm -
1 stop8h 25m
Deal found 9/24![Delta logo]()
$765
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/146:50 am -
1 stop9h 22m
Sat 1/168:55 am -
1 stop10h 35m
Deal found 9/24![United Airlines logo]()
$772
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/317:35 am -
Nonstop5h 26m
Sun 2/77:28 pm -
Nonstop5h 43m
Deal found 9/21![Copa Airlines logo]()
$757
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/186:00 am -
1 stop6h 55m
Thu 2/253:20 pm -
1 stop7h 50m
Deal found 9/21![Delta logo]()
$832
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:35 am -
Nonstop5h 26m
Fri 12/48:06 am -
Nonstop5h 40m
Deal found 9/21![Copa Airlines logo]()
$765
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:04 am -
1 stop6h 55m
Sun 11/153:29 pm -
1 stop8h 25m
Deal found 9/20![Delta logo]()
$852
This United deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:13 pm -
1 stop17h 37m
Sat 12/59:48 am -
2 stops24h 20m
Deal found 9/24![Multiple Airlines logo]()
$1,491
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:35 pm -
2 stops34h 15m
Sat 11/149:48 am -
2 stops15h 57m
Deal found 9/23![United Airlines logo]()
$1,245
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/126:00 am -
1 stop6h 55m
Wed 2/173:20 pm -
1 stop7h 50m
Deal found 9/22![Delta logo]()
$1,104
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:35 am -
1 stop24h 13m
Sun 1/107:55 pm -
1 stop17h 51m
Deal found 9/21![Copa Airlines logo]()
$1,133
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:30 am -
2 stops26h 20m
Thu 12/39:48 am -
2 stops36h 49m
Deal found 9/24![United Airlines logo]()
$1,274
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:04 am -
1 stop6h 55m
Fri 10/162:24 pm -
1 stop8h 09m
Deal found 9/24![Delta logo]()
$1,113
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:35 pm -
2 stops34h 15m
Thu 11/129:48 am -
2 stops25h 22m
Deal found 9/21![United Airlines logo]()
$1,274
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop7h 05m
Tue 11/243:29 pm -
1 stop8h 25m
Deal found 9/21![Delta logo]()
$1,145
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:45 am -
2 stops26h 03m
Sun 1/109:48 am -
2 stops35h 10m
Deal found 9/20![United Airlines logo]()
$1,483
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:44 pm -
2 stops42h 18m
Sat 11/283:31 pm -
1 stop8h 23m
Deal found 9/23![Delta logo]()
$1,296
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:35 am -
1 stop7h 34m
Sat 1/27:55 pm -
1 stop17h 51m
Deal found 9/20![Copa Airlines logo]()
$1,569
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:04 am -
1 stop6h 55m
Mon 11/303:29 pm -
1 stop8h 25m
Deal found 9/23![Delta logo]()
$1,403
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:04 am -
1 stop6h 55m
Mon 10/192:24 pm -
1 stop8h 09m
Deal found 9/22![Delta logo]()
$1,463
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:00 am -
1 stop7h 02m
Sat 11/283:31 pm -
1 stop8h 23m
Deal found 9/23![Delta logo]()
$1,471
Last-minute flights from Chicago to PanamaDiscover last-minute flight deals from Chicago to Panama. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Panama. Data last updated September 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:55 pm -
2 stops15h 21m
Wed 9/301:16 pm -
2 stops18h 26m
Deal found 9/22![American Airlines logo]()
$721
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am -
1 stop7h 16m
Thu 10/82:02 pm -
1 stop17h 45m
Deal found 9/20![American Airlines logo]()
$717
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:29 pm -
1 stop17h 33m
Thu 4/81:49 pm -
1 stop10h 38m
Deal found 9/21![American Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:29 pm -
1 stop17h 33m
Wed 4/141:49 pm -
1 stop10h 38m
Deal found 9/20![American Airlines logo]()
$667
This Avianca deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:20 pm -
1 stop14h 55m
Mon 10/2610:05 am -
1 stop11h 25m
Deal found 9/20![Avianca logo]()
$706
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:01 am -
1 stop11h 16m
Tue 11/108:00 pm -
1 stop17h 46m
Deal found 9/23![Copa Airlines logo]()
$832
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:21 am -
1 stop14h 10m
Mon 11/309:31 pm -
2 stops15h 02m
Deal found 9/22![Multiple Airlines logo]()
$848
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:29 pm -
1 stop17h 33m
Wed 10/282:02 pm -
1 stop17h 45m
Deal found 9/21![American Airlines logo]()
$722
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:20 pm -
1 stop17h 50m
Wed 10/289:45 am -
1 stop15h 20m
Deal found 9/21![Copa Airlines logo]()
$872
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2511:30 pm -
1 stop15h 45m
Wed 10/282:30 am -
1 stop19h 00m
Deal found 9/19![Avianca logo]()
$592
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 am -
1 stop7h 57m
Wed 11/43:13 pm -
1 stop20h 52m
Deal found 9/22![American Airlines logo]()
$716
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:04 am -
1 stop6h 55m
Sat 10/312:24 pm -
1 stop8h 09m
Deal found 9/22![Delta logo]()
$828
One-way flights from Chicago to PanamaSearch for one-way flight options from Chicago to Panama. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Chicago to Panama. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/3112:04 am -
1 stop12h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$263
This Copa Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:13 pm -
Nonstop5h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Copa Airlines logo]()
$266
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:55 am -
1 stop11h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/18:55 pm -
2 stops15h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![American Airlines logo]()
$276
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![American Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/47:10 pm -
1 stop17h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/36:05 am -
1 stop8h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/48:00 pm -
1 stop16h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$336
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:00 am -
1 stop8h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![American Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/314:10 pm -
2 stops20h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:22 am -
1 stop14h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/51:18 pm -
2 stops29h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$381
Find flight deals from Chicago to Panama
Keep the following information in mind while searching for Chicago to Panama flight deals. Data was last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $592 (Avianca) |
One-way from | $266 (Copa Airlines) |
Popular in | July |
Cheapest in | May |
Average price | $745 |
Good round-trip deal | $533 or less |
Good one-way deal | $249 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Chicago to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Sun 11/22
2:13 pm-8:37 pm
Nonstop5h 24m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$266
Quickest round-trip
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Mon 3/1
7:35 am-1:54 pm
Nonstop5h 19m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$266
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Fri 11/20
6:55 am-7:38 pm
1 stop11h 43m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$348
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Tue 12/22
9:43 pm-7:38 pm
1 stop20h 55m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$367
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Tue 10/13
6:21 am-8:31 pm
1 stop14h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$399
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Tue 12/22
9:23 pm-7:45 pm
2 stops45h 22m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$422
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Wed 1/13
2:13 pm-8:38 pm
Nonstop5h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$425
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 11/12
2:13 pm-8:37 pm
Nonstop5h 24m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$425
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 3/4
7:08 am-1:31 pm
Nonstop5h 23m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$425
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Wed 9/30
6:25 am-12:35 am
3 stops18h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$458
Showing 1-10 of 48 resultsSorted by cheapest first
Best time to book a flight from Chicago to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Chicago with our price prediction graph.
ORD-PTY
MDW-PTY
ORD-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Panama
CHI-PA0
ORD-PTY
MDW-PTY
ORD-DAV
What is the cheapest month to book a flight from Chicago to Panama?
Currently, April is the cheapest month in which you can book a flight from Chicago to Panama (average of $584). Flying from Chicago to Panama in September is currently the most expensive (average of $790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to PA?
Find hourly flight availability from Chicago to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 24, 2026.
One of the essential ways to save on airfare from Chicago to Panama is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 15% on airfare.
Weekly flight availability from Chicago to Panama
Explore weekly flight availability from Chicago to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 24, 2026.
The most flights from CHI to PA0 are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).
How often are flights from Chicago to Panama delayed?
About 13% of weekly flights between Chicago and Panama have experienced delays in the past year, with the average delay time being 121 minutes.
What is the most punctual flight time for Chicago to Panama flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Chicago to Panama flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 12% of flights being delayed.
How far ahead should I book a flight from Chicago to Panama?
The best time to book flights from Chicago to Panama is 30 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Chicago to Panama?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Panama. Price data was last updated on September 19, 2026.
Travelers seeking maximum savings on their Chicago to Panama flight should consider departing on Thursday evenings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 24, 2026.
See what other customers who have flown with Delta,Copa Airlines, andUnited Airlines from Chicago to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Food
7.2
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Food
7.2
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Food
7.2
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Food
7.2
Overall
7.8
Crew
8.5
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Chicago to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Panama by cabin class
Find flights from Chicago to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Panama flights
Browse other Chicago and Panama flight options. Last updated on September 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Chicago to Panama
Discover the top 4 airlines that operate flights from Chicago to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$316 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$465 | Average$638 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$577 | Average$767 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$596 | Average$730 | FlexibilityNo cancel fee | On-time71% |