$62+ Cheap flights from Missouri to Ohio
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CLE
May 29 — Jun 51
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to OhioExplore the most affordable flight options available from Missouri to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Missouri to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:27 pm
STL
- CMH
1 stop22h 43m
Frontier
Tue 5/266:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Deal found 4/27![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- CVG
1 stop15h 40m
Frontier
Sat 6/612:46 pm
CVG
- MCI
1 stop5h 43m
Frontier
Deal found 4/25![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:27 pm
STL
- CMH
1 stop22h 43m
Frontier
Sun 5/246:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Deal found 4/27![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- DTW
1 stop21h 40m
Frontier
Tue 6/21:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Deal found 4/28![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- CVG
1 stop15h 40m
Frontier
Sat 6/612:46 pm
CVG
- MCI
1 stop5h 43m
Frontier
Deal found 4/25![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- CLE
1 stop16h 59m
Frontier
Tue 6/27:30 am
CLE
- STL
1 stop11h 03m
Frontier
Deal found 4/28![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 pm
STL
- CLE
1 stop17h 23m
Frontier
Wed 6/37:24 pm
CLE
- STL
1 stop23h 09m
Frontier
Deal found 4/27![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Wed 6/36:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Deal found 4/29![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
STL
- CLE
1 stop16h 59m
Frontier
Thu 6/46:54 am
CLE
- STL
1 stop11h 39m
Frontier
Deal found 4/25![Frontier logo]()
$136
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:45 pm
STL
- CLE
Nonstop1h 30m
Southwest
Tue 6/27:40 pm
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 4/28![Southwest logo]()
$137
This Frontier deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:18 pm
STL
- CLE
1 stop9h 14m
Frontier
Sun 5/176:54 am
CLE
- STL
1 stop11h 00m
Frontier
Deal found 4/24![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:24 pm
MCI
- CVG
1 stop16h 17m
Frontier
Wed 6/1012:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Deal found 4/26![Frontier logo]()
$153
Best flights from Missouri to OhioDiscover carefully curated flight deals from Missouri to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Missouri to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:45 pm
STL
- CLE
1 stop5h 35m
Southwest
Wed 6/37:40 pm
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 4/27![Southwest logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
STL
- CLE
2 stops19h 09m
Frontier
Thu 6/46:54 am
CLE
- STL
1 stop11h 39m
Frontier
Deal found 4/25![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:18 pm
STL
- DTW
2 stops25h 19m
Multiple Airlines
Tue 5/191:31 pm
DTW
- STL
1 stop20h 24m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$252
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:00 am
STL
- PIT
1 stop5h 44m
Delta
Mon 6/85:30 am
PIT
- STL
1 stop5h 16m
Delta
Deal found 4/29![Delta logo]()
$275
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:00 am
STL
- PIT
1 stop4h 09m
United Airlines
Fri 6/196:11 pm
PIT
- STL
1 stop5h 33m
United Airlines
Deal found 4/26![United Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:55 pm
SGF
- CMH
1 stop12h 51m
American Airlines
Mon 8/172:46 pm
CMH
- SGF
1 stop7h 43m
American Airlines
Deal found 4/28![American Airlines logo]()
$352
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:34 pm
MCI
- CLE
1 stop19h 23m
Frontier
Wed 6/37:30 am
CLE
- MCI
1 stop10h 59m
Frontier
Deal found 4/29![Frontier logo]()
$181
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:35 am
STL
- DTW
1 stop3h 10m
Southwest
Tue 6/27:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Deal found 4/28![Southwest logo]()
$207
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:51 am
STL
- PIT
1 stop5h 26m
Delta
Mon 7/67:00 am
PIT
- STL
1 stop6h 34m
Delta
Deal found 4/25![Delta logo]()
$280
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:00 am
STL
- PIT
1 stop6h 07m
United Airlines
Sun 5/246:16 pm
PIT
- STL
1 stop4h 05m
United Airlines
Deal found 4/28![United Airlines logo]()
$306
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:50 pm
STL
- DTW
Nonstop1h 30m
Southwest
Wed 9/163:35 pm
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 4/29![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:04 pm
STL
- DTW
Nonstop1h 33m
Delta
Sun 5/314:36 pm
DTW
- STL
Nonstop1h 40m
Delta
Deal found 4/28![Delta logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:45 pm
MCI
- CLE
2 stops27h 44m
Multiple Airlines
Wed 7/89:42 pm
CLE
- MCI
1 stop12h 13m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$320
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/173:10 pm
STL
- PIT
1 stop6h 10m
Southwest
Fri 6/198:15 pm
PIT
- STL
Nonstop1h 45m
Southwest
Deal found 4/26![Southwest logo]()
$280
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:45 am
STL
- PIT
1 stop3h 28m
Delta
Mon 6/81:57 pm
PIT
- STL
1 stop5h 10m
Delta
Deal found 4/24![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:55 pm
SGF
- CMH
1 stop4h 20m
United Airlines
Mon 8/1711:58 am
CMH
- SGF
1 stop5h 23m
United Airlines
Deal found 4/26![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:30 pm
MCI
- CVG
1 stop3h 50m
Southwest
Thu 5/216:50 pm
CVG
- MCI
1 stop5h 45m
Southwest
Deal found 4/27![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:00 am
STL
- PIT
1 stop5h 42m
Delta
Tue 7/147:02 am
PIT
- STL
1 stop6h 15m
Delta
Deal found 4/28![Delta logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:35 am
MCI
- PIT
1 stop21h 14m
Multiple Airlines
Mon 5/188:15 pm
PIT
- MCI
2 stops46h 14m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:15 am
STL
- PIT
1 stop5h 50m
Southwest
Tue 7/147:45 pm
PIT
- STL
Nonstop1h 45m
Southwest
Deal found 4/24![Southwest logo]()
$283
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:08 am
STL
- CMH
1 stop5h 32m
Delta
Thu 6/186:00 am
CMH
- STL
1 stop4h 46m
Delta
Deal found 4/26![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:50 pm
MCI
- CVG
1 stop7h 38m
United Airlines
Sat 6/66:50 am
CVG
- MCI
1 stop4h 39m
United Airlines
Deal found 4/27![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:55 pm
STL
- CMH
Nonstop1h 20m
Southwest
Mon 5/188:25 pm
CMH
- STL
Nonstop1h 30m
Southwest
Deal found 4/25![Southwest logo]()
$289
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:01 pm
STL
- CMH
1 stop4h 29m
Delta
Sun 6/78:08 am
CMH
- STL
1 stop5h 26m
Delta
Deal found 4/28![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:53 am
MCI
- CLE
1 stop4h 06m
United Airlines
Thu 7/237:08 pm
CLE
- MCI
1 stop5h 51m
United Airlines
Deal found 4/28![United Airlines logo]()
$382
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:25 pm
STL
- CMH
Nonstop1h 20m
Southwest
Mon 5/257:10 am
CMH
- STL
Nonstop1h 30m
Southwest
Deal found 4/28![Southwest logo]()
$289
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:30 am
STL
- CMH
1 stop3h 57m
Delta
Sun 6/146:30 am
CMH
- STL
1 stop4h 02m
Delta
Deal found 4/25![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:00 am
MCI
- CLE
1 stop4h 12m
United Airlines
Sun 10/117:20 pm
CLE
- MCI
1 stop5h 32m
United Airlines
Deal found 4/28![United Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/710:20 am
STL
- CLE
Nonstop1h 30m
Southwest
Tue 6/98:25 am
CLE
- STL
1 stop3h 50m
Southwest
Deal found 4/25![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:00 am
STL
- CLE
1 stop4h 32m
Delta
Fri 7/106:11 pm
CLE
- STL
1 stop6h 42m
Delta
Deal found 4/24![Delta logo]()
$299
Last-minute flights from Missouri to OhioDiscover last-minute flight deals from Missouri to Ohio. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Ohio. Data last updated April 29, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:34 pm
MCI
- CLE
1 stop20h 08m
Frontier
Mon 5/186:54 am
CLE
- MCI
1 stop11h 35m
Frontier
Deal found 4/27![Frontier logo]()
$162
This Frontier deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:18 pm
STL
- CLE
1 stop9h 14m
Frontier
Sun 5/176:54 am
CLE
- STL
1 stop11h 00m
Frontier
Deal found 4/24![Frontier logo]()
$140
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:45 pm
STL
- CLE
Nonstop1h 30m
Southwest
Sat 5/234:50 pm
CLE
- STL
1 stop3h 55m
Southwest
Deal found 4/27![Southwest logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:27 pm
STL
- CMH
1 stop22h 43m
Frontier
Tue 5/266:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Deal found 4/27![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:27 pm
STL
- CMH
1 stop22h 43m
Frontier
Sun 5/246:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Deal found 4/27![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- DTW
1 stop21h 40m
Frontier
Tue 6/21:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Deal found 4/28![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- CLE
1 stop16h 59m
Frontier
Tue 6/27:30 am
CLE
- STL
1 stop11h 03m
Frontier
Deal found 4/28![Frontier logo]()
$126
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:45 pm
STL
- CLE
Nonstop1h 30m
Southwest
Tue 6/27:40 pm
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 4/28![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 pm
STL
- CLE
1 stop17h 23m
Frontier
Wed 6/37:24 pm
CLE
- STL
1 stop23h 09m
Frontier
Deal found 4/27![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Wed 6/36:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Deal found 4/29![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:24 pm
MCI
- CVG
1 stop15h 40m
Frontier
Wed 6/312:46 pm
CVG
- MCI
1 stop5h 43m
Frontier
Deal found 4/27![Frontier logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:33 pm
STL
- DTW
1 stop5h 05m
Multiple Airlines
Sun 5/316:30 am
DTW
- STL
1 stop27h 25m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$165
One-way flights from Missouri to OhioSearch for one-way flight options from Missouri to Ohio. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Missouri to Ohio. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:16 pm
MCI
- CLE
1 stop13h 37m
Frontier
Deal found 4/26![Frontier logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:13 pm
STL
- DTW
1 stop18h 54m
Frontier
Deal found 4/27![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:16 pm
MCI
- CMH
1 stop21h 48m
Frontier
Deal found 4/27![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:16 pm
MCI
- DTW
1 stop29h 24m
Frontier
Deal found 4/28![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/28![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:16 pm
MCI
- CMH
1 stop21h 49m
Frontier
Deal found 4/27![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:33 pm
STL
- CLE
1 stop16h 59m
Frontier
Deal found 4/29![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 pm
STL
- CMH
1 stop22h 43m
Frontier
Deal found 4/28![Frontier logo]()
$65
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 4/27![Southwest logo]()
$69
This Frontier deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/25![Frontier logo]()
$70
This Super.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:19 pm
STL
- CLE
1 stop6h 30m
Frontier
Deal found 4/24![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:27 pm
STL
- CLE
1 stop24h 52m
Frontier
Deal found 4/29![Frontier logo]()
$71
Find flight deals from Missouri to Ohio
Keep the following information in mind while searching for Missouri to Ohio flight deals. Data was last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $122 (Kiwi.com) |
One-way from | $62 (Kiwi.com) |
Popular in | April |
Cheapest in | September |
Average price | $426 |
Good round-trip deal | $222 or less |
Good one-way deal | $167 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Missouri to Ohio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Wed 5/27
1:45 pm-8:20 pm
1 stop5h 35m
Cleveland Hopkins Intl
Wed 6/3
7:40 pm-8:20 pm
Nonstop1h 40m
$147
St. LouisCleveland
STL - CLE
STLCLE
Lambert-St Louis
Tue 6/2
6:33 pm-2:42 pm
2 stops19h 09m
Cleveland Hopkins Intl
Thu 6/4
6:54 am-5:33 pm
1 stop11h 39m
$181
Kansas CityCleveland
MCI - CLE
MCICLE
Kansas City
Thu 5/28
2:34 pm-10:57 am
1 stop19h 23m
Cleveland Hopkins Intl
Wed 6/3
7:30 am-5:29 pm
1 stop10h 59m
$181
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Tue 5/26
5:35 am-9:45 am
1 stop3h 10m
Detroit Metropolitan Wayne County
Tue 6/2
7:00 am-7:45 am
Nonstop1h 45m
$207
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Fri 5/15
9:18 pm-11:37 pm
2 stops25h 19m
Detroit Metropolitan Wayne County
Tue 5/19
1:31 pm-8:55 am
1 stop20h 24m
$252
St. LouisPittsburgh
STL - PIT
STLPIT
Lambert-St Louis
Thu 6/4
6:00 am-12:44 pm
1 stop5h 44m
Pittsburgh
Mon 6/8
5:30 am-9:46 am
1 stop5h 16m
$275
St. LouisDetroit
STL - DTW
STLDTW
Lambert-St Louis
Mon 9/14
6:50 pm-9:20 pm
Nonstop1h 30m
Detroit Metropolitan Wayne County
Wed 9/16
3:35 pm-4:10 pm
Nonstop1h 35m
$279
St. LouisPittsburgh
STL - PIT
STLPIT
Lambert-St Louis
Wed 7/1
10:51 am-5:17 pm
1 stop5h 26m
Pittsburgh
Mon 7/6
7:00 am-12:34 pm
1 stop6h 34m
$280
St. LouisPittsburgh
STL - PIT
STLPIT
Lambert-St Louis
Wed 6/17
3:10 pm-10:20 pm
1 stop6h 10m
Pittsburgh
Fri 6/19
8:15 pm-9:00 pm
Nonstop1h 45m
$280
Kansas CityCincinnati
MCI - CVG
MCICVG
Kansas City
Wed 5/20
3:30 pm-8:20 pm
1 stop3h 50m
Cincinnati Cinci./N. Kentucky
Thu 5/21
6:50 pm-11:35 pm
1 stop5h 45m
$282
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Ohio
Have a flexible travel schedule? Discover the best time to fly to Ohio from Missouri with our price prediction graph.
MCI-CLE
STL-DTW
MCI-CMH
MCI-DTW
STL-CLE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Ohio
USMO-USOH
MCI-CLE
STL-DTW
MCI-CMH
MCI-DTW
How far ahead should I book a flight from Missouri to Ohio?
The price you pay for your flight from Missouri to Ohio may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Missouri to Ohio?
Currently, September is the cheapest month in which you can book a flight from Missouri to Ohio (average of $89). Flying from Missouri to Ohio in April is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to OH?
Find hourly flight availability from Missouri to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2026.
One of the essential ways to save on airfare from Missouri to Ohio is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 24% on airfare.
How much does it cost to fly round-trip from Missouri to Ohio?
Reviews of airlines servicing Ohio
Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated April 29, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Missouri to Ohio by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Missouri to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Ohio
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Ohio by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Ohio by cabin class
Find flights from Missouri to Ohio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Ohio flights
Browse other Missouri and Ohio flight options. Last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Ohio
Find the right flight back to Missouri after your stay in Ohio
Missouri to Ohio flights
Consider these flights traveling from Missouri to Ohio.
Top 6 airlines flying from Missouri to Ohio
Discover the top 6 airlines that operate flights from Missouri to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$235 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$168 | Average$384 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$168 | Average$378 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$391 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$196 | Average$408 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$203 | Average$328 | FlexibilityNo cancel fee | On-time65% |