$68+ Cheap flights from Ohio to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — MCI
Jul 5 — Jul 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Ohio to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Ohio to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Ohio to MissouriExplore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:05 am
CLE
- STL
Nonstop1h 35m
Southwest
Tue 7/2810:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 6/3![Southwest logo]()
$137
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:35 am
CLE
- STL
1 stop6h 10m
Southwest
Wed 7/294:00 pm
STL
- CLE
1 stop3h 30m
Southwest
Deal found 6/2![Southwest logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:07 pm
CMH
- MCI
1 stop24h 17m
Frontier
Sat 9/56:19 pm
MCI
- CMH
1 stop21h 53m
Frontier
Deal found 6/5![Frontier logo]()
$157
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:59 pm
PIT
- STL
1 stop4h 15m
American Airlines
Wed 8/1910:44 am
STL
- PIT
1 stop6h 29m
American Airlines
Deal found 6/1![American Airlines logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:53 pm
CVG
- MCI
1 stop5h 17m
Frontier
Wed 7/226:07 pm
MCI
- CVG
1 stop16h 06m
Frontier
Deal found 6/4![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:44 pm
CMH
- MCI
1 stop24h 26m
Frontier
Wed 7/226:07 pm
MCI
- CMH
1 stop21h 52m
Frontier
Deal found 6/5![Frontier logo]()
$164
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:25 pm
CLE
- STL
Nonstop1h 35m
Southwest
Thu 8/67:40 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 6/1![Southwest logo]()
$166
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:40 am
CLE
- STL
2 stops7h 45m
Southwest
Wed 7/293:15 pm
STL
- CLE
2 stops6h 25m
Southwest
Deal found 6/5![Southwest logo]()
$167
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Tue 7/214:00 pm
STL
- DTW
1 stop3h 25m
Southwest
Deal found 6/1![Southwest logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:53 pm
CVG
- MCI
1 stop5h 17m
Frontier
Mon 7/206:07 pm
MCI
- CVG
1 stop16h 06m
Frontier
Deal found 6/4![Frontier logo]()
$175
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:50 am
DTW
- STL
Nonstop1h 41m
Delta
Sun 7/196:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 6/1![Delta logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:07 pm
CMH
- MCI
1 stop24h 17m
Frontier
Mon 8/246:19 pm
MCI
- CMH
1 stop21h 53m
Frontier
Deal found 6/4![Frontier logo]()
$177
Best flights from Ohio to MissouriDiscover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
Discover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Wed 7/295:40 am
STL
- CLE
1 stop3h 25m
Southwest
Deal found 6/5![Southwest logo]()
$147
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:50 am
DTW
- STL
Nonstop1h 41m
Delta
Fri 7/316:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 6/1![Delta logo]()
$177
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:00 am
CLE
- MCI
1 stop4h 22m
United Airlines
Thu 7/95:37 pm
MCI
- CLE
1 stop5h 12m
United Airlines
Deal found 6/5![United Airlines logo]()
$275
This Booking.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:15 pm
CVG
- MCI
1 stop17h 45m
Frontier
Thu 6/251:45 pm
MCI
- CVG
1 stop28h 46m
Frontier
Deal found 5/31![Frontier logo]()
$347
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/912:28 pm
DTW
- STL
Nonstop1h 37m
Delta
Mon 7/136:09 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 6/1![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Fri 7/175:50 am
STL
- CLE
1 stop5h 40m
Southwest
Deal found 6/1![Southwest logo]()
$219
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:05 am
CLE
- STL
Nonstop1h 35m
Southwest
Sun 7/265:50 am
STL
- CLE
1 stop3h 25m
Southwest
Deal found 6/3![Southwest logo]()
$219
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Thu 7/305:50 am
STL
- CLE
1 stop5h 40m
Southwest
Deal found 6/3![Southwest logo]()
$219
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:18 am
CLE
- STL
1 stop5h 47m
Delta
Fri 7/176:09 pm
STL
- CLE
1 stop4h 47m
Delta
Deal found 6/2![Delta logo]()
$241
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Wed 7/83:10 pm
STL
- DTW
1 stop6h 20m
Southwest
Deal found 6/5![Southwest logo]()
$219
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:05 pm
CLE
- STL
1 stop4h 25m
United Airlines
Mon 6/225:29 pm
STL
- CLE
1 stop5h 29m
United Airlines
Deal found 6/5![United Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:40 am
CLE
- STL
2 stops10h 30m
Southwest
Mon 8/242:45 pm
STL
- CLE
2 stops6h 10m
Southwest
Deal found 6/4![Southwest logo]()
$231
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:25 am
CMH
- MCI
1 stop4h 16m
Delta
Wed 9/306:30 am
MCI
- CMH
1 stop3h 52m
Delta
Deal found 6/1![Delta logo]()
$288
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:20 pm
CMH
- STL
1 stop4h 03m
United Airlines
Mon 7/65:59 pm
STL
- CMH
1 stop5h 00m
United Airlines
Deal found 6/1![United Airlines logo]()
$325
This Priceline deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:20 am
DTW
- MCI
1 stop7h 02m
Frontier
Sun 10/42:17 pm
MCI
- DTW
1 stop9h 07m
Frontier
Deal found 5/31![Frontier logo]()
$358
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:05 am
DTW
- STL
2 stops8h 45m
Southwest
Wed 10/287:30 am
STL
- DTW
2 stops9h 55m
Southwest
Deal found 6/3![Southwest logo]()
$239
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:55 pm
CMH
- STL
1 stop4h 31m
United Airlines
Sun 6/287:20 am
STL
- CMH
1 stop4h 57m
United Airlines
Deal found 6/1![United Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:50 am
DTW
- STL
Nonstop1h 42m
Delta
Sun 6/286:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 6/2![Delta logo]()
$314
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:30 am
PIT
- MCI
2 stops10h 42m
United Airlines
Tue 9/86:39 pm
MCI
- PIT
1 stop4h 36m
United Airlines
Deal found 6/1![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:45 am
PIT
- STL
Nonstop1h 45m
Southwest
Wed 7/297:10 pm
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 6/5![Southwest logo]()
$257
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:23 am
CLE
- MCI
1 stop4h 57m
United Airlines
Sun 9/610:00 am
MCI
- CLE
1 stop4h 29m
United Airlines
Deal found 6/4![United Airlines logo]()
$331
This Delta deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:00 am
CLE
- MCI
1 stop6h 49m
Delta
Sat 7/114:04 pm
MCI
- CLE
1 stop5h 37m
Delta
Deal found 6/1![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:40 am
CLE
- STL
1 stop6h 55m
Southwest
Sun 9/277:40 am
STL
- CLE
1 stop5h 45m
Southwest
Deal found 6/4![Southwest logo]()
$258
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:00 am
CVG
- MCI
1 stop5h 29m
United Airlines
Sat 7/46:41 pm
MCI
- CVG
1 stop4h 11m
United Airlines
Deal found 5/31![United Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:30 am
PIT
- MCI
1 stop7h 57m
Delta
Mon 10/125:26 pm
MCI
- PIT
1 stop5h 53m
Delta
Deal found 6/2![Delta logo]()
$355
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:35 am
CLE
- STL
1 stop6h 10m
Southwest
Sun 7/1211:45 am
STL
- CLE
2 stops6h 50m
Southwest
Deal found 6/1![Southwest logo]()
$273
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:00 am
PIT
- MCI
1 stop4h 29m
United Airlines
Fri 7/315:37 pm
MCI
- PIT
1 stop5h 22m
United Airlines
Deal found 5/31![United Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 am
PIT
- STL
Nonstop1h 45m
Southwest
Mon 9/217:35 pm
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 6/2![Southwest logo]()
$277
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:25 pm
DTW
- MCI
Nonstop1h 58m
Delta
Mon 10/510:32 am
MCI
- DTW
Nonstop1h 55m
Delta
Deal found 6/2![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:40 am
CLE
- STL
1 stop6h 55m
Southwest
Mon 9/212:45 pm
STL
- CLE
2 stops6h 10m
Southwest
Deal found 6/2![Southwest logo]()
$280
Last-minute flights from Ohio to MissouriDiscover last-minute flight deals from Ohio to Missouri. Data last updated June 5, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Missouri. Data last updated June 5, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 pm
CMH
- MCI
1 stop24h 21m
Frontier
Mon 6/296:16 pm
MCI
- CMH
1 stop21h 49m
Frontier
Deal found 6/1![Frontier logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:37 am
CLE
- MCI
1 stop11h 44m
Frontier
Wed 7/86:07 pm
MCI
- CLE
1 stop13h 45m
Frontier
Deal found 6/4![Frontier logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/312:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Fri 7/106:07 pm
MCI
- CVG
1 stop16h 41m
Frontier
Deal found 6/5![Frontier logo]()
$166
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/147:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Tue 7/214:00 pm
STL
- DTW
1 stop3h 25m
Southwest
Deal found 6/1![Southwest logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:53 pm
CVG
- MCI
1 stop5h 17m
Frontier
Wed 7/226:07 pm
MCI
- CVG
1 stop16h 06m
Frontier
Deal found 6/4![Frontier logo]()
$164
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:25 pm
DTW
- STL
1 stop3h 30m
Southwest
Sun 7/196:45 pm
STL
- DTW
1 stop4h 25m
Southwest
Deal found 6/1![Southwest logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:53 pm
CVG
- MCI
1 stop5h 17m
Frontier
Mon 7/206:07 pm
MCI
- CVG
1 stop16h 06m
Frontier
Deal found 6/4![Frontier logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:44 pm
CMH
- MCI
1 stop24h 26m
Frontier
Wed 7/226:07 pm
MCI
- CMH
1 stop21h 52m
Frontier
Deal found 6/5![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:44 pm
CMH
- MCI
1 stop24h 26m
Frontier
Mon 7/276:07 pm
MCI
- CMH
1 stop21h 52m
Frontier
Deal found 6/3![Frontier logo]()
$181
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:05 am
CLE
- STL
Nonstop1h 35m
Southwest
Tue 7/2810:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 6/3![Southwest logo]()
$137
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:40 am
CLE
- STL
2 stops7h 45m
Southwest
Wed 7/293:15 pm
STL
- CLE
2 stops6h 25m
Southwest
Deal found 6/5![Southwest logo]()
$167
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:35 am
CLE
- STL
1 stop6h 10m
Southwest
Wed 7/294:00 pm
STL
- CLE
1 stop3h 30m
Southwest
Deal found 6/2![Southwest logo]()
$157
One-way flights from Ohio to MissouriSearch for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated June 5, 2026.
Search for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated June 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:22 pm
DTW
- STL
1 stop7h 01m
Frontier
Deal found 6/3![Frontier logo]()
$68
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Deal found 6/2![Southwest logo]()
$69
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:18 am
CLE
- STL
1 stop5h 47m
Delta
Deal found 6/2![Delta logo]()
$74
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:25 am
CLE
- STL
1 stop5h 10m
Southwest
Deal found 6/3![Southwest logo]()
$79
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 6/1![Southwest logo]()
$79
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/299:14 pm
CLE
- STL
1 stop3h 44m
American Airlines
Deal found 6/1![American Airlines logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:19 pm
DTW
- MCI
1 stop24h 41m
Frontier
Deal found 6/3![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 pm
CMH
- MCI
1 stop24h 21m
Frontier
Deal found 6/4![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:44 pm
CMH
- MCI
1 stop24h 26m
Frontier
Deal found 6/3![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:44 pm
CMH
- STL
1 stop16h 13m
Frontier
Deal found 6/3![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:50 am
DTW
- MCI
1 stop11h 26m
Frontier
Deal found 6/4![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:44 pm
CMH
- MCI
1 stop24h 26m
Frontier
Deal found 6/4![Frontier logo]()
$87
Find flight deals from Ohio to Missouri
Keep the following information in mind while searching for Ohio to Missouri flight deals. Data was last updated June 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $137 (Southwest) |
One-way from | $68 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $357 |
Good round-trip deal | $378 or less |
Good one-way deal | $211 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
Use the filters below to find and compare flights from Ohio to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 7/28
7:55 pm-8:30 pm
Nonstop1h 35m
Lambert-St Louis
Wed 7/29
5:40 am-10:05 am
1 stop3h 25m
$147
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 7/23
8:50 am-9:31 am
Nonstop1h 41m
Lambert-St Louis
Fri 7/31
6:30 am-9:04 am
Nonstop1h 34m
$177
Quickest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 7/9
12:28 pm-1:05 pm
Nonstop1h 37m
Lambert-St Louis
Mon 7/13
6:09 pm-8:44 pm
Nonstop1h 35m
$177
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Wed 7/15
7:55 pm-8:30 pm
Nonstop1h 35m
Lambert-St Louis
Fri 7/17
5:50 am-12:30 pm
1 stop5h 40m
$219
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 7/21
7:05 am-7:40 am
Nonstop1h 35m
Lambert-St Louis
Sun 7/26
5:50 am-10:15 am
1 stop3h 25m
$219
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Wed 7/22
7:55 pm-8:30 pm
Nonstop1h 35m
Lambert-St Louis
Thu 7/30
5:50 am-12:30 pm
1 stop5h 40m
$219
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 7/8
7:05 am-7:40 am
Nonstop1h 35m
Lambert-St Louis
Wed 7/8
3:10 pm-10:30 pm
1 stop6h 20m
$219
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Thu 8/20
5:40 am-3:10 pm
2 stops10h 30m
Lambert-St Louis
Mon 8/24
2:45 pm-9:55 pm
2 stops6h 10m
$231
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 10/21
6:05 am-1:50 pm
2 stops8h 45m
Lambert-St Louis
Wed 10/28
7:30 am-6:25 pm
2 stops9h 55m
$239
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Wed 7/15
8:18 am-1:05 pm
1 stop5h 47m
Lambert-St Louis
Fri 7/17
6:09 pm-11:56 pm
1 stop4h 47m
$241
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Ohio with our price prediction graph.
DTW-STL
CLE-STL
DTW-MCI
CMH-MCI
CMH-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Missouri
USOH-USMO
DTW-STL
CLE-STL
DTW-MCI
CMH-MCI
What is the cheapest month to book a flight from Ohio to Missouri?
Currently, October is the cheapest month in which you can book a flight from Ohio to Missouri (average of $85). Flying from Ohio to Missouri in December is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to MO?
Find hourly flight availability from Ohio to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 5, 2026.
It’s optimal to fly from Ohio to Missouri in the evening. By choosing this option you can save up to 21% on the cost of your flight, compared to a flight in the afternoon.
How much does it cost to fly round-trip from Ohio to Missouri?
How far ahead should I book a flight from Ohio to Missouri?
To ensure you get the cheapest price possible for a flight from Ohio to Missouri, you should look to book at least 89 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Ohio to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Ohio to Missouri. Price data was last updated on May 30, 2026.
Travelers seeking maximum savings on their Ohio to Missouri flight should consider departing on Saturday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated June 5, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Ohio to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Ohio to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Ohio to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to Missouri by cabin class
Find flights from Ohio to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ohio and Missouri flights
Browse other Ohio and Missouri flight options. Last updated on June 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Ohio after your stay in Missouri
Ohio to Missouri flights
Consider these flights traveling from Ohio to Missouri.
Top 5 airlines flying from Ohio to Missouri
Discover the top 5 airlines that operate flights from Ohio to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$85 | Average$193 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$99 | Average$350 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$185 | Average$364 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$186 | Average$388 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$210 | Average$376 | FlexibilityNo cancel fee | On-time69% |