$59+ Cheap flights from Ohio to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — STL
May 9 — May 161
Round-trip
1 adult, Economy
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Cheapest flights from Ohio to MissouriExplore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:40 pm
CLE
- STL
Nonstop1h 40m
Southwest
Wed 5/2711:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 4/7![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:46 pm
CLE
- MCI
1 stop26h 38m
Frontier
Mon 6/156:19 pm
MCI
- CLE
1 stop13h 34m
Frontier
Deal found 4/6![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Sat 5/165:27 pm
STL
- CMH
1 stop22h 43m
Frontier
Deal found 4/8![Frontier logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:24 pm
CLE
- STL
1 stop22h 30m
Frontier
Wed 5/135:27 pm
STL
- CLE
1 stop14h 26m
Frontier
Deal found 4/8![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Sat 6/65:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/4![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 4/8![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:35 pm
CMH
- STL
1 stop13h 15m
Frontier
Mon 5/48:23 pm
STL
- CMH
1 stop19h 47m
Frontier
Deal found 4/4![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:54 am
CLE
- STL
1 stop11h 00m
Frontier
Mon 5/185:27 pm
STL
- CLE
1 stop14h 26m
Frontier
Deal found 4/8![Frontier logo]()
$136
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:25 pm
CLE
- STL
1 stop4h 45m
Southwest
Wed 8/196:30 am
STL
- CLE
1 stop3h 30m
Southwest
Deal found 4/6![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2512:08 pm
CLE
- MCI
1 stop26h 41m
Frontier
Mon 8/176:19 pm
MCI
- CLE
1 stop13h 34m
Frontier
Deal found 4/4![Frontier logo]()
$138
This Frontier deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:31 pm
CLE
- STL
1 stop7h 48m
Frontier
Sat 5/28:23 pm
STL
- CLE
1 stop10h 21m
Frontier
Deal found 4/4![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:17 pm
CVG
- MCI
1 stop18h 49m
Frontier
Sat 5/92:34 pm
MCI
- CVG
1 stop19h 10m
Frontier
Deal found 4/7![Frontier logo]()
$142
Best flights from Ohio to MissouriDiscover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:40 pm
CLE
- STL
Nonstop1h 40m
Southwest
Wed 5/2711:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 4/7![Southwest logo]()
$117
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:02 pm
DTW
- STL
Nonstop1h 42m
Delta
Tue 5/1910:19 am
STL
- DTW
Nonstop1h 31m
Delta
Deal found 4/5![Delta logo]()
$177
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:09 pm
CVG
- MCI
1 stop4h 55m
United Airlines
Tue 5/123:22 pm
MCI
- CVG
1 stop4h 08m
United Airlines
Deal found 4/5![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 pm
CLE
- STL
1 stop6h 40m
Southwest
Wed 8/1910:45 am
STL
- CLE
2 stops6h 00m
Southwest
Deal found 4/6![Southwest logo]()
$142
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:20 am
CAK
- STL
1 stop6h 27m
American Airlines
Mon 5/1112:27 pm
STL
- CAK
1 stop4h 16m
American Airlines
Deal found 4/6![American Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:40 pm
DTW
- MCI
1 stop3h 20m
Southwest
Wed 5/135:25 am
MCI
- DTW
1 stop3h 20m
Southwest
Deal found 4/8![Southwest logo]()
$143
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:02 pm
DTW
- STL
Nonstop1h 42m
Delta
Mon 5/410:50 am
STL
- DTW
Nonstop1h 29m
Delta
Deal found 4/5![Delta logo]()
$213
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Wed 5/1310:30 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/6![Southwest logo]()
$177
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Tue 5/125:45 am
STL
- DTW
2 stops8h 50m
Southwest
Deal found 4/6![Southwest logo]()
$192
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:09 pm
CMH
- STL
1 stop4h 14m
United Airlines
Mon 5/259:23 am
STL
- CMH
1 stop5h 05m
United Airlines
Deal found 4/4![United Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
PIT
- STL
1 stop5h 34m
Delta
Wed 5/66:50 pm
STL
- PIT
1 stop4h 44m
Delta
Deal found 4/6![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:15 pm
DTW
- STL
Nonstop1h 40m
Southwest
Tue 5/56:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/7![Southwest logo]()
$195
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:53 pm
CMH
- STL
1 stop3h 52m
United Airlines
Sat 5/29:00 am
STL
- CMH
1 stop5h 20m
United Airlines
Deal found 4/6![United Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:05 am
PIT
- STL
1 stop4h 29m
Delta
Sun 5/36:50 pm
STL
- PIT
1 stop4h 45m
Delta
Deal found 4/5![Delta logo]()
$267
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:13 pm
CAK
- STL
1 stop5h 04m
American Airlines
Mon 5/1112:27 pm
STL
- CAK
1 stop4h 16m
American Airlines
Deal found 4/4![American Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:10 pm
DTW
- STL
Nonstop1h 45m
Southwest
Sun 5/3110:15 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/8![Southwest logo]()
$217
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:25 am
CAK
- STL
1 stop6h 21m
United Airlines
Tue 5/265:41 pm
STL
- CAK
1 stop5h 14m
United Airlines
Deal found 4/4![United Airlines logo]()
$297
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:46 pm
PIT
- STL
1 stop4h 50m
Delta
Wed 5/66:48 am
STL
- PIT
1 stop5h 34m
Delta
Deal found 4/6![Delta logo]()
$271
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:10 pm
CAK
- STL
1 stop5h 44m
American Airlines
Wed 6/177:00 am
STL
- CAK
2 stops9h 21m
American Airlines
Deal found 4/6![American Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:15 am
PIT
- STL
Nonstop1h 50m
Southwest
Mon 4/277:40 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/4![Southwest logo]()
$217
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:55 pm
CMH
- STL
1 stop4h 15m
Delta
Thu 5/217:05 am
STL
- CMH
1 stop5h 44m
Delta
Deal found 4/5![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:57 pm
CAK
- STL
1 stop4h 19m
United Airlines
Wed 6/178:00 am
STL
- CAK
1 stop4h 26m
United Airlines
Deal found 4/6![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:20 pm
CLE
- STL
2 stops8h 05m
Southwest
Fri 6/264:25 pm
STL
- CLE
2 stops6h 50m
Southwest
Deal found 4/6![Southwest logo]()
$228
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:00 pm
CMH
- STL
1 stop5h 59m
Delta
Fri 5/227:01 pm
STL
- CMH
1 stop4h 29m
Delta
Deal found 4/5![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:15 pm
CLE
- MCI
1 stop5h 44m
American Airlines
Wed 4/295:35 am
MCI
- CLE
1 stop4h 06m
American Airlines
Deal found 4/8![American Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:12 am
CAK
- STL
1 stop6h 26m
United Airlines
Sun 9/205:32 pm
STL
- CAK
1 stop5h 23m
United Airlines
Deal found 4/5![United Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:05 am
PIT
- STL
2 stops7h 55m
Southwest
Tue 5/56:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/4![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:54 pm
CLE
- MCI
1 stop14h 37m
Delta
Tue 6/166:25 am
MCI
- CLE
1 stop6h 21m
Delta
Deal found 4/6![Delta logo]()
$283
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:10 pm
PIT
- STL
Nonstop1h 50m
Southwest
Sat 5/236:55 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/5![Southwest logo]()
$241
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:05 am
CMH
- STL
1 stop6h 12m
Delta
Wed 8/51:22 pm
STL
- CMH
1 stop4h 41m
Delta
Deal found 4/5![Delta logo]()
$297
Last-minute flights from Ohio to MissouriDiscover last-minute flight deals from Ohio to Missouri. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Missouri. Data last updated April 9, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:31 pm
CLE
- STL
1 stop7h 48m
Frontier
Sat 5/28:23 pm
STL
- CLE
1 stop10h 21m
Frontier
Deal found 4/4![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 4/8![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:35 pm
CMH
- STL
1 stop13h 15m
Frontier
Mon 5/48:23 pm
STL
- CMH
1 stop19h 47m
Frontier
Deal found 4/4![Frontier logo]()
$133
This Frontier deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:17 pm
CVG
- MCI
1 stop18h 49m
Frontier
Sat 5/92:34 pm
MCI
- CVG
1 stop19h 10m
Frontier
Deal found 4/7![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Mon 5/48:23 pm
STL
- DTW
1 stop15h 13m
Frontier
Deal found 4/7![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop10h 49m
Frontier
Thu 5/76:55 pm
STL
- DTW
1 stop28h 44m
Frontier
Deal found 4/6![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:24 pm
CLE
- STL
1 stop22h 30m
Frontier
Wed 5/135:27 pm
STL
- CLE
1 stop14h 26m
Frontier
Deal found 4/8![Frontier logo]()
$129
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:10 am
DTW
- MCI
1 stop4h 40m
Southwest
Wed 5/139:20 am
MCI
- DTW
1 stop5h 15m
Southwest
Deal found 4/8![Southwest logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Sat 5/165:27 pm
STL
- CMH
1 stop22h 43m
Frontier
Deal found 4/8![Frontier logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:54 am
CLE
- STL
1 stop11h 00m
Frontier
Mon 5/185:27 pm
STL
- CLE
1 stop14h 26m
Frontier
Deal found 4/8![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2512:08 pm
CLE
- MCI
1 stop26h 41m
Frontier
Mon 8/176:19 pm
MCI
- CLE
1 stop13h 34m
Frontier
Deal found 4/4![Frontier logo]()
$138
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:40 pm
CLE
- STL
Nonstop1h 40m
Southwest
Wed 5/2711:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 4/7![Southwest logo]()
$117
One-way flights from Ohio to MissouriSearch for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:05 am
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 4/7![Southwest logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:54 pm
CVG
- MCI
1 stop5h 30m
Frontier
Deal found 4/6![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/78:46 pm
CLE
- MCI
1 stop21h 43m
Frontier
Deal found 4/8![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:59 pm
DTW
- MCI
1 stop28h 30m
Frontier
Deal found 4/7![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1912:54 pm
CVG
- MCI
1 stop29h 30m
Frontier
Deal found 4/4![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:01 pm
CLE
- STL
1 stop15h 54m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:50 am
DTW
- STL
1 stop11h 43m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:05 pm
CMH
- MCI
1 stop24h 24m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:10 am
DTW
- MCI
1 stop12h 14m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/108:47 pm
CLE
- STL
1 stop13h 08m
Frontier
Deal found 4/8![Frontier logo]()
$67
This Priceline deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:46 pm
CVG
- MCI
1 stop5h 43m
Frontier
Deal found 4/4![Frontier logo]()
$70
Find flight deals from Ohio to Missouri
Keep the following information in mind while searching for Ohio to Missouri flight deals. Data was last updated April 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $117 (Southwest) |
One-way from | $59 (Southwest) |
Popular in | January |
Cheapest in | August |
Average price | $319 |
Good round-trip deal | $334 or less |
Good one-way deal | $173 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Ohio to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 5/26
7:40 pm-8:20 pm
Nonstop1h 40m
Lambert-St Louis
Wed 5/27
11:30 am-2:00 pm
Nonstop1h 30m
$117
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Wed 8/12
6:00 pm-11:40 pm
1 stop6h 40m
Lambert-St Louis
Wed 8/19
10:45 am-5:45 pm
2 stops6h 00m
$142
DetroitKansas City
DTW - MCI
DTWMCI
Detroit Metropolitan Wayne County
Wed 5/6
1:40 pm-4:00 pm
1 stop3h 20m
Kansas City
Wed 5/13
5:25 am-9:45 am
1 stop3h 20m
$143
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 5/5
8:02 pm-8:44 pm
Nonstop1h 42m
Lambert-St Louis
Tue 5/19
10:19 am-12:50 pm
Nonstop1h 31m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 5/6
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Wed 5/13
10:30 am-1:00 pm
Nonstop1h 30m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 5/6
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Tue 5/12
5:45 am-3:35 pm
2 stops8h 50m
$192
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Mon 5/4
8:15 pm-8:55 pm
Nonstop1h 40m
Lambert-St Louis
Tue 5/5
6:45 pm-9:15 pm
Nonstop1h 30m
$195
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 4/30
8:02 pm-8:44 pm
Nonstop1h 42m
Lambert-St Louis
Mon 5/4
10:50 am-1:19 pm
Nonstop1h 29m
$213
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 5/26
7:10 pm-7:55 pm
Nonstop1h 45m
Lambert-St Louis
Sun 5/31
10:15 am-12:45 pm
Nonstop1h 30m
$217
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 4/25
7:15 am-8:05 am
Nonstop1h 50m
Lambert-St Louis
Mon 4/27
7:40 pm-10:15 pm
Nonstop1h 35m
$217
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Ohio with our price prediction graph.
CLE-STL
DTW-STL
CVG-MCI
CAK-STL
DTW-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Missouri
USOH-USMO
CLE-STL
DTW-STL
CVG-MCI
CAK-STL
What is the cheapest month to book a flight from Ohio to Missouri?
Currently, October is the cheapest month in which you can book a flight from Ohio to Missouri (average of $85). Flying from Ohio to Missouri in June is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to MO?
Find hourly flight availability from Ohio to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 9, 2026.
It’s optimal to fly from Ohio to Missouri in the evening. By choosing this option you can save up to 24% on the cost of your flight, compared to a flight in the afternoon.
What is the cheapest day to fly from Ohio to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Ohio to Missouri. Price data was last updated on April 4, 2026.
Travelers seeking maximum savings on their Ohio to Missouri flight should consider departing on Saturday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Ohio to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 9, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Ohio to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Ohio to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Ohio to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to Missouri by cabin class
Find flights from Ohio to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ohio and Missouri flights
Browse other Ohio and Missouri flight options. Last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Ohio after your stay in Missouri
Ohio to Missouri flights
Consider these flights traveling from Ohio to Missouri.
Top 5 airlines flying from Ohio to Missouri
Discover the top 5 airlines that operate flights from Ohio to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$99 | Average$205 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$99 | Average$360 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$171 | Average$351 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$195 | Average$362 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$210 | Average$368 | FlexibilityNo cancel fee | On-time69% |