$59+ Cheap flights from Ohio to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/13. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — MCI
Jun 19 — Jun 261
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Ohio to MissouriExplore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.
Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:37 am
CLE
- STL
1 stop11h 53m
Frontier
Tue 6/236:31 pm
STL
- CLE
1 stop16h 21m
Frontier
Deal found 5/19![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:54 am
CLE
- MCI
1 stop11h 35m
Frontier
Wed 6/106:16 pm
MCI
- CLE
1 stop13h 37m
Frontier
Deal found 5/16![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:51 pm
CLE
- STL
1 stop16h 01m
Frontier
Sun 6/286:31 pm
STL
- CLE
1 stop25h 24m
Frontier
Deal found 5/19![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/112:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Sat 8/86:16 pm
MCI
- CVG
1 stop15h 57m
Frontier
Deal found 5/16![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:24 pm
CLE
- STL
1 stop14h 28m
Frontier
Mon 6/295:06 pm
STL
- CLE
1 stop14h 47m
Frontier
Deal found 5/18![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:37 am
CLE
- MCI
1 stop11h 44m
Frontier
Sat 6/276:16 pm
MCI
- CLE
1 stop13h 37m
Frontier
Deal found 5/18![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Mon 6/156:16 pm
MCI
- CVG
1 stop15h 58m
Frontier
Deal found 5/17![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:37 am
CLE
- STL
1 stop11h 53m
Frontier
Sat 7/45:06 pm
STL
- CLE
1 stop14h 46m
Frontier
Deal found 5/19![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 pm
CMH
- MCI
1 stop24h 21m
Frontier
Mon 7/66:16 pm
MCI
- CMH
1 stop21h 48m
Frontier
Deal found 5/17![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:51 pm
CLE
- MCI
1 stop24h 30m
Frontier
Wed 7/156:16 pm
MCI
- CLE
1 stop16h 33m
Frontier
Deal found 5/18![Frontier logo]()
$126
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Wed 6/247:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 5/17![Southwest logo]()
$137
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:00 pm
CLE
- STL
1 stop5h 39m
Delta
Wed 6/176:30 am
STL
- CLE
1 stop6h 16m
Delta
Deal found 5/18![Delta logo]()
$147
Best flights from Ohio to MissouriDiscover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 20, 2026.
Discover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:37 am
CLE
- STL
1 stop11h 53m
Frontier
Tue 7/76:33 pm
STL
- CLE
1 stop16h 16m
Frontier
Deal found 5/19![Frontier logo]()
$126
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:35 am
CLE
- STL
1 stop6h 10m
Southwest
Wed 7/227:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 5/17![Southwest logo]()
$147
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:00 pm
DTW
- STL
Nonstop1h 37m
Delta
Tue 8/46:25 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 5/16![Delta logo]()
$209
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:16 pm
PIT
- STL
1 stop4h 10m
United Airlines
Fri 7/101:13 pm
STL
- PIT
1 stop4h 22m
United Airlines
Deal found 5/17![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:05 pm
CLE
- STL
2 stops9h 20m
Southwest
Tue 6/235:40 am
STL
- CLE
1 stop3h 25m
Southwest
Deal found 5/19![Southwest logo]()
$162
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
CVG
- MCI
1 stop6h 43m
American Airlines
Sun 7/55:30 am
MCI
- CVG
1 stop6h 36m
American Airlines
Deal found 5/19![American Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:20 pm
PIT
- STL
1 stop3h 50m
Southwest
Thu 9/176:10 am
STL
- PIT
1 stop6h 55m
Southwest
Deal found 5/20![Southwest logo]()
$197
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:30 am
PIT
- STL
1 stop4h 02m
Delta
Mon 6/297:12 pm
STL
- PIT
1 stop4h 43m
Delta
Deal found 5/16![Delta logo]()
$235
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:10 am
PIT
- STL
2 stops8h 15m
Southwest
Wed 9/94:45 pm
STL
- PIT
1 stop3h 45m
Southwest
Deal found 5/17![Southwest logo]()
$202
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:30 am
PIT
- STL
1 stop5h 16m
Delta
Mon 6/297:12 pm
STL
- PIT
1 stop4h 43m
Delta
Deal found 5/15![Delta logo]()
$235
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:25 pm
PIT
- STL
1 stop5h 58m
Delta
Sat 7/46:00 am
STL
- PIT
1 stop5h 47m
Delta
Deal found 5/16![Delta logo]()
$235
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:45 pm
CLE
- STL
1 stop3h 25m
Southwest
Tue 7/77:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 5/19![Southwest logo]()
$218
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:00 am
CMH
- STL
1 stop6h 11m
United Airlines
Sat 6/205:29 pm
STL
- CMH
1 stop3h 50m
United Airlines
Deal found 5/15![United Airlines logo]()
$295
This Frontier deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:54 am
CLE
- STL
1 stop11h 39m
Frontier
Mon 6/811:38 am
STL
- CLE
1 stop8h 14m
Frontier
Deal found 5/19![Frontier logo]()
$310
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:30 am
PIT
- STL
1 stop4h 02m
Delta
Tue 6/306:00 am
STL
- PIT
1 stop5h 42m
Delta
Deal found 5/16![Delta logo]()
$235
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:30 pm
DTW
- STL
Nonstop1h 35m
Southwest
Tue 6/235:40 am
STL
- DTW
1 stop3h 20m
Southwest
Deal found 5/17![Southwest logo]()
$219
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:00 am
CMH
- STL
1 stop4h 11m
United Airlines
Sun 6/215:29 pm
STL
- CMH
1 stop5h 30m
United Airlines
Deal found 5/17![United Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:24 pm
CLE
- MCI
2 stops18h 36m
Frontier
Mon 7/66:07 pm
MCI
- CLE
1 stop13h 45m
Frontier
Deal found 5/19![Frontier logo]()
$313
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:20 am
CMH
- STL
1 stop4h 19m
United Airlines
Sun 6/215:29 pm
STL
- CMH
1 stop5h 30m
United Airlines
Deal found 5/15![United Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:20 pm
PIT
- STL
1 stop7h 50m
Southwest
Tue 6/305:15 am
STL
- PIT
1 stop5h 50m
Southwest
Deal found 5/18![Southwest logo]()
$235
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:51 pm
CLE
- MCI
1 stop5h 33m
American Airlines
Sun 7/55:30 am
MCI
- CLE
1 stop7h 14m
American Airlines
Deal found 5/19![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:50 am
DTW
- STL
1 stop4h 21m
United Airlines
Tue 7/286:00 am
STL
- DTW
2 stops12h 02m
United Airlines
Deal found 5/15![United Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:54 pm
CMH
- STL
1 stop4h 36m
United Airlines
Sat 6/67:05 pm
STL
- CMH
1 stop3h 54m
United Airlines
Deal found 5/16![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:30 pm
PIT
- STL
1 stop3h 55m
Southwest
Fri 7/107:55 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 5/17![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:00 am
PIT
- MCI
1 stop5h 09m
Delta
Mon 10/126:42 pm
MCI
- PIT
1 stop4h 37m
Delta
Deal found 5/19![Delta logo]()
$347
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:10 pm
PIT
- MCI
1 stop4h 35m
United Airlines
Mon 8/315:08 pm
MCI
- PIT
1 stop6h 07m
United Airlines
Deal found 5/17![United Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:40 am
PIT
- STL
2 stops8h 45m
Southwest
Wed 9/1610:15 am
STL
- PIT
1 stop6h 25m
Southwest
Deal found 5/20![Southwest logo]()
$280
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:00 am
PIT
- MCI
1 stop6h 27m
Delta
Wed 10/146:42 pm
MCI
- PIT
1 stop4h 37m
Delta
Deal found 5/16![Delta logo]()
$372
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:55 am
DTW
- STL
Nonstop1h 35m
Southwest
Tue 6/167:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/15![Southwest logo]()
$285
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:10 pm
PIT
- MCI
1 stop4h 35m
United Airlines
Sat 8/2210:00 am
MCI
- PIT
1 stop4h 25m
United Airlines
Deal found 5/15![United Airlines logo]()
$347
Last-minute flights from Ohio to MissouriDiscover last-minute flight deals from Ohio to Missouri. Data last updated May 20, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Missouri. Data last updated May 20, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:24 pm
CLE
- STL
1 stop14h 31m
Frontier
Mon 6/85:27 pm
STL
- CLE
1 stop14h 26m
Frontier
Deal found 5/15![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:54 am
CLE
- MCI
1 stop11h 35m
Frontier
Wed 6/106:16 pm
MCI
- CLE
1 stop13h 37m
Frontier
Deal found 5/16![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Mon 6/156:16 pm
MCI
- CVG
1 stop15h 58m
Frontier
Deal found 5/17![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:37 am
CLE
- STL
1 stop11h 53m
Frontier
Tue 6/236:31 pm
STL
- CLE
1 stop16h 21m
Frontier
Deal found 5/19![Frontier logo]()
$121
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:00 pm
CLE
- STL
1 stop5h 39m
Delta
Wed 6/176:30 am
STL
- CLE
1 stop6h 16m
Delta
Deal found 5/18![Delta logo]()
$147
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:55 pm
CLE
- STL
Nonstop1h 35m
Southwest
Wed 6/247:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 5/17![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 pm
CMH
- STL
1 stop15h 52m
Frontier
Sat 6/275:06 pm
STL
- CMH
1 stop22h 59m
Frontier
Deal found 5/15![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:37 am
CLE
- MCI
1 stop11h 44m
Frontier
Sat 6/276:16 pm
MCI
- CLE
1 stop13h 37m
Frontier
Deal found 5/18![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2412:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Sat 7/116:16 pm
MCI
- CVG
1 stop15h 57m
Frontier
Deal found 5/15![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:51 pm
CLE
- STL
1 stop16h 01m
Frontier
Sun 6/286:31 pm
STL
- CLE
1 stop25h 24m
Frontier
Deal found 5/19![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:24 pm
CLE
- STL
1 stop14h 28m
Frontier
Mon 6/295:06 pm
STL
- CLE
1 stop14h 47m
Frontier
Deal found 5/18![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:37 am
CLE
- STL
1 stop11h 53m
Frontier
Sat 7/45:06 pm
STL
- CLE
1 stop14h 46m
Frontier
Deal found 5/19![Frontier logo]()
$126
One-way flights from Ohio to MissouriSearch for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated May 20, 2026.
Search for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated May 20, 2026.
This Trip.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:10 am
DTW
- MCI
1 stop12h 11m
Frontier
Deal found 5/16![Frontier logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:54 pm
CVG
- MCI
1 stop5h 27m
Frontier
Deal found 5/16![Frontier logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 pm
CMH
- MCI
1 stop24h 10m
Frontier
Deal found 5/20![Frontier logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/196:00 pm
CMH
- STL
1 stop15h 57m
Frontier
Deal found 5/18![Frontier logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:37 am
CLE
- STL
1 stop11h 53m
Frontier
Deal found 5/16![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2712:52 pm
CVG
- MCI
1 stop5h 29m
Frontier
Deal found 5/19![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/252:02 pm
DTW
- STL
1 stop19h 50m
Frontier
Deal found 5/18![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:37 am
CLE
- MCI
1 stop11h 44m
Frontier
Deal found 5/18![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:56 pm
DTW
- MCI
1 stop27h 25m
Frontier
Deal found 5/19![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 pm
CMH
- STL
1 stop15h 52m
Frontier
Deal found 5/18![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/22:02 pm
DTW
- MCI
1 stop28h 19m
Frontier
Deal found 5/18![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:51 pm
CLE
- STL
1 stop16h 06m
Frontier
Deal found 5/19![Frontier logo]()
$65
Find flight deals from Ohio to Missouri
Keep the following information in mind while searching for Ohio to Missouri flight deals. Data was last updated May 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $121 (Kiwi.com) |
One-way from | $59 (Trip.com) |
Popular in | January |
Cheapest in | August |
Average price | $369 |
Good round-trip deal | $396 or less |
Good one-way deal | $202 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Ohio to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 6/30
6:37 am-5:30 pm
1 stop11h 53m
Lambert-St Louis
Tue 7/7
6:33 pm-11:49 am
1 stop16h 16m
$126
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 7/21
5:35 am-10:45 am
1 stop6h 10m
Lambert-St Louis
Wed 7/22
7:15 pm-9:45 pm
Nonstop1h 30m
$147
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 6/16
12:05 pm-8:25 pm
2 stops9h 20m
Lambert-St Louis
Tue 6/23
5:40 am-10:05 am
1 stop3h 25m
$162
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Tue 9/15
7:20 pm-10:10 pm
1 stop3h 50m
Lambert-St Louis
Thu 9/17
6:10 am-2:05 pm
1 stop6h 55m
$197
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 8/22
6:10 am-1:25 pm
2 stops8h 15m
Lambert-St Louis
Wed 9/9
4:45 pm-9:30 pm
1 stop3h 45m
$202
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 7/29
8:00 pm-8:37 pm
Nonstop1h 37m
Lambert-St Louis
Tue 8/4
6:25 pm-9:00 pm
Nonstop1h 35m
$209
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Thu 7/2
4:45 pm-7:10 pm
1 stop3h 25m
Lambert-St Louis
Tue 7/7
7:15 pm-9:45 pm
Nonstop1h 30m
$218
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 6/16
6:30 pm-7:05 pm
Nonstop1h 35m
Lambert-St Louis
Tue 6/23
5:40 am-10:00 am
1 stop3h 20m
$219
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Mon 6/29
6:30 am-9:32 am
1 stop4h 02m
Lambert-St Louis
Mon 6/29
7:12 pm-12:55 am
1 stop4h 43m
$235
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Tue 6/23
5:30 am-9:46 am
1 stop5h 16m
Lambert-St Louis
Mon 6/29
7:12 pm-12:55 am
1 stop4h 43m
$235
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Ohio with our price prediction graph.
CLE-STL
CLE-MCI
CVG-MCI
CMH-STL
PIT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Missouri
USOH-USMO
CLE-STL
CLE-MCI
CVG-MCI
CMH-STL
What is the cheapest month to book a flight from Ohio to Missouri?
Currently, October is the cheapest month in which you can book a flight from Ohio to Missouri (average of $85). Flying from Ohio to Missouri in December is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to MO?
Find hourly flight availability from Ohio to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 20, 2026.
It’s optimal to fly from Ohio to Missouri in the evening. By choosing this option you can save up to 21% on the cost of your flight, compared to a flight in the afternoon.
How much does it cost to fly round-trip from Ohio to Missouri?
How far ahead should I book a flight from Ohio to Missouri?
To ensure you get the cheapest price possible for a flight from Ohio to Missouri, you should look to book at least 89 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Ohio to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Ohio to Missouri. Price data was last updated on May 16, 2026.
Travelers seeking maximum savings on their Ohio to Missouri flight should consider departing on Saturday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 20, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Ohio to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Entertainment
7.5
Overall
7.9
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Ohio to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Ohio to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to Missouri by cabin class
Find flights from Ohio to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ohio and Missouri flights
Browse other Ohio and Missouri flight options. Last updated on May 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Ohio after your stay in Missouri
Ohio to Missouri flights
Consider these flights traveling from Ohio to Missouri.
Top 5 airlines flying from Ohio to Missouri
Discover the top 5 airlines that operate flights from Ohio to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$85 | Average$195 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$99 | Average$352 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$185 | Average$360 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$201 | Average$384 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$210 | Average$377 | FlexibilityNo cancel fee | On-time69% |