$59+ Cheap flights from Ohio to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — STL
Apr 21 — Apr 281
Round-trip
1 adult, Economy
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Find cheap flights from Ohio to Missouri with Cheapflights
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Cheapest flights from Ohio to MissouriExplore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:10 pm
CLE
- STL
Nonstop1h 40m
Southwest
Wed 4/156:45 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 3/19![Southwest logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Wed 4/228:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 3/18![Frontier logo]()
$134
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:31 pm
CLE
- STL
1 stop7h 54m
Frontier
Wed 4/158:23 pm
STL
- CLE
1 stop10h 21m
Frontier
Deal found 3/19![Frontier logo]()
$140
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:48 am
DTW
- STL
1 stop12h 37m
Frontier
Thu 4/1611:25 am
STL
- DTW
1 stop6h 21m
Frontier
Deal found 3/21![Frontier logo]()
$140
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:30 pm
CLE
- STL
2 stops7h 30m
Southwest
Fri 4/178:10 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 3/19![Southwest logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:33 pm
DTW
- STL
1 stop19h 17m
Frontier
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 3/19![Frontier logo]()
$145
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:10 pm
CLE
- STL
Nonstop1h 40m
Southwest
Sat 4/115:40 am
STL
- CLE
1 stop3h 10m
Southwest
Deal found 3/19![Southwest logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Thu 4/2311:25 am
STL
- DTW
1 stop6h 21m
Frontier
Deal found 3/21![Frontier logo]()
$154
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:31 pm
CLE
- STL
1 stop6h 11m
Delta
Mon 4/135:59 pm
STL
- CLE
1 stop4h 56m
Delta
Deal found 3/17![Delta logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:54 am
CLE
- MCI
1 stop11h 35m
Frontier
Fri 5/86:24 pm
MCI
- CLE
1 stop25h 33m
Frontier
Deal found 3/19![Frontier logo]()
$158
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:45 pm
CLE
- STL
1 stop4h 01m
American Airlines
Thu 4/165:20 am
STL
- CLE
1 stop6h 22m
American Airlines
Deal found 3/20![American Airlines logo]()
$159
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:20 am
CVG
- MCI
1 stop13h 41m
Frontier
Fri 4/1711:19 am
MCI
- CVG
1 stop6h 17m
Frontier
Deal found 3/20![Frontier logo]()
$160
Best flights from Ohio to MissouriDiscover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
Discover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:20 pm
CLE
- STL
1 stop3h 40m
Southwest
Tue 4/2111:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 3/17![Southwest logo]()
$127
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:59 am
DTW
- STL
Nonstop1h 47m
Delta
Mon 4/136:48 am
STL
- DTW
Nonstop1h 29m
Delta
Deal found 3/18![Delta logo]()
$205
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:49 am
PIT
- STL
1 stop4h 45m
United Airlines
Sat 5/307:22 am
STL
- PIT
1 stop4h 47m
United Airlines
Deal found 3/21![United Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:10 pm
CLE
- STL
Nonstop1h 40m
Southwest
Thu 4/168:10 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 3/18![Southwest logo]()
$137
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:00 am
CVG
- MCI
1 stop5h 01m
American Airlines
Wed 4/159:39 am
MCI
- CVG
1 stop5h 54m
American Airlines
Deal found 3/17![American Airlines logo]()
$282
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:10 pm
CLE
- STL
Nonstop1h 40m
Southwest
Fri 4/248:10 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 3/18![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:35 pm
CMH
- STL
1 stop13h 15m
Frontier
Sun 4/194:59 pm
STL
- CMH
2 stops17h 16m
Frontier
Deal found 3/18![Frontier logo]()
$322
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/133:45 pm
CLE
- STL
2 stops8h 30m
Southwest
Wed 4/155:35 am
STL
- CLE
1 stop3h 20m
Southwest
Deal found 3/19![Southwest logo]()
$152
This Mytrip deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:34 pm
DTW
- MCI
3 stops31h 19m
Spirit Airlines
Mon 4/612:24 pm
MCI
- DTW
2 stops21h 48m
Spirit Airlines
Deal found 3/17![Spirit Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:40 pm
CLE
- STL
1 stop6h 34m
Delta
Sun 4/196:50 pm
STL
- CLE
1 stop4h 44m
Delta
Deal found 3/19![Delta logo]()
$228
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:04 pm
DTW
- STL
1 stop5h 53m
United Airlines
Wed 4/157:45 am
STL
- DTW
2 stops9h 38m
United Airlines
Deal found 3/17![United Airlines logo]()
$282
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:15 pm
PIT
- STL
Nonstop1h 45m
Southwest
Wed 6/1010:25 am
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 3/17![Southwest logo]()
$217
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:22 am
CMH
- STL
1 stop7h 19m
American Airlines
Sun 4/125:51 am
STL
- CMH
1 stop4h 21m
American Airlines
Deal found 3/17![American Airlines logo]()
$294
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:05 pm
PIT
- STL
Nonstop1h 50m
Southwest
Sat 5/306:55 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 3/21![Southwest logo]()
$217
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:00 am
CMH
- STL
1 stop4h 48m
United Airlines
Tue 5/1910:25 am
STL
- CMH
1 stop5h 26m
United Airlines
Deal found 3/22![United Airlines logo]()
$297
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:48 pm
CMH
- STL
1 stop4h 29m
Delta
Thu 6/186:00 am
STL
- CMH
1 stop6h 40m
Delta
Deal found 3/21![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:05 am
CMH
- STL
1 stop4h 25m
American Airlines
Sun 4/267:05 am
STL
- CMH
1 stop6h 07m
American Airlines
Deal found 3/17![American Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:59 pm
CMH
- STL
1 stop5h 00m
Delta
Sun 6/76:45 am
STL
- CMH
1 stop3h 35m
Delta
Deal found 3/18![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/129:00 am
CMH
- STL
1 stop4h 11m
United Airlines
Sun 6/145:41 pm
STL
- CMH
1 stop5h 18m
United Airlines
Deal found 3/20![United Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:55 am
PIT
- STL
Nonstop1h 50m
Southwest
Wed 4/153:55 pm
STL
- PIT
1 stop3h 50m
Southwest
Deal found 3/18![Southwest logo]()
$227
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:11 pm
DTW
- STL
2 stops10h 02m
United Airlines
Wed 4/227:45 am
STL
- DTW
1 stop6h 37m
United Airlines
Deal found 3/19![United Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:10 pm
PIT
- STL
1 stop4h 05m
Southwest
Tue 4/2110:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 3/19![Southwest logo]()
$227
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:44 pm
DAY
- STL
1 stop5h 52m
Delta
Mon 4/276:50 pm
STL
- DAY
1 stop4h 27m
Delta
Deal found 3/21![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:05 am
PIT
- STL
2 stops7h 55m
Southwest
Thu 4/910:15 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 3/18![Southwest logo]()
$232
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:05 pm
DAY
- STL
1 stop4h 11m
United Airlines
Sun 6/146:00 am
STL
- DAY
1 stop4h 04m
United Airlines
Deal found 3/19![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:15 am
CMH
- STL
1 stop4h 31m
Delta
Fri 4/106:59 pm
STL
- CMH
1 stop4h 25m
Delta
Deal found 3/19![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:30 pm
DAY
- STL
1 stop6h 26m
American Airlines
Tue 5/197:00 am
STL
- DAY
1 stop5h 22m
American Airlines
Deal found 3/17![American Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:05 am
PIT
- STL
2 stops7h 55m
Southwest
Wed 4/296:45 pm
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 3/18![Southwest logo]()
$232
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:39 am
CMH
- MCI
1 stop4h 46m
United Airlines
Wed 4/226:05 am
MCI
- CMH
1 stop5h 49m
United Airlines
Deal found 3/17![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:40 pm
CLE
- MCI
1 stop6h 21m
Delta
Tue 5/55:46 pm
MCI
- CLE
1 stop5h 09m
Delta
Deal found 3/19![Delta logo]()
$333
Last-minute flights from Ohio to MissouriDiscover last-minute flight deals from Ohio to Missouri. Data last updated March 22, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Missouri. Data last updated March 22, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:10 pm
CLE
- STL
Nonstop1h 40m
Southwest
Sat 4/115:40 am
STL
- CLE
1 stop3h 10m
Southwest
Deal found 3/19![Southwest logo]()
$147
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:20 am
CVG
- MCI
1 stop13h 41m
Frontier
Fri 4/1711:19 am
MCI
- CVG
1 stop6h 17m
Frontier
Deal found 3/20![Frontier logo]()
$160
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:31 pm
CLE
- STL
1 stop6h 11m
Delta
Mon 4/135:59 pm
STL
- CLE
1 stop4h 56m
Delta
Deal found 3/17![Delta logo]()
$157
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:10 pm
CLE
- STL
Nonstop1h 40m
Southwest
Wed 4/156:45 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 3/19![Southwest logo]()
$127
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:31 pm
CLE
- STL
1 stop7h 54m
Frontier
Wed 4/158:23 pm
STL
- CLE
1 stop10h 21m
Frontier
Deal found 3/19![Frontier logo]()
$140
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:48 am
DTW
- STL
1 stop12h 37m
Frontier
Thu 4/1611:25 am
STL
- DTW
1 stop6h 21m
Frontier
Deal found 3/21![Frontier logo]()
$140
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:45 pm
CLE
- STL
1 stop4h 01m
American Airlines
Thu 4/165:20 am
STL
- CLE
1 stop6h 22m
American Airlines
Deal found 3/20![American Airlines logo]()
$159
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:30 pm
CLE
- STL
2 stops7h 30m
Southwest
Fri 4/178:10 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 3/19![Southwest logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:33 pm
CLE
- MCI
1 stop20h 25m
Frontier
Fri 4/1711:19 am
MCI
- CLE
1 stop22h 24m
Frontier
Deal found 3/18![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Wed 4/228:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 3/18![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Thu 4/2311:25 am
STL
- DTW
1 stop6h 21m
Frontier
Deal found 3/21![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:33 pm
DTW
- STL
1 stop19h 17m
Frontier
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 3/19![Frontier logo]()
$145
One-way flights from Ohio to MissouriSearch for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
Search for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:05 am
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 3/18![Southwest logo]()
$59
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:00 am
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 3/18![Southwest logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Deal found 3/20![Frontier logo]()
$69
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:46 pm
CLE
- STL
1 stop7h 33m
Frontier
Deal found 3/20![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:50 am
DTW
- STL
1 stop11h 43m
Frontier
Deal found 3/18![Frontier logo]()
$70
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Deal found 3/20![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/21![Frontier logo]()
$74
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:31 am
CLE
- STL
1 stop12h 54m
Frontier
Deal found 3/20![Frontier logo]()
$76
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:55 pm
CVG
- MCI
1 stop25h 54m
Frontier
Deal found 3/20![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/18![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:53 pm
PIT
- STL
1 stop11h 26m
Frontier
Deal found 3/20![Frontier logo]()
$76
This Trip.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:00 pm
CLE
- MCI
1 stop16h 58m
Frontier
Deal found 3/19![Frontier logo]()
$78
Find flight deals from Ohio to Missouri
Keep the following information in mind while searching for Ohio to Missouri flight deals. Data was last updated March 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $127 (Southwest) |
One-way from | $59 (Southwest) |
Popular in | January |
Cheapest in | August |
Average price | $336 |
Good round-trip deal | $379 or less |
Good one-way deal | $194 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Ohio to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 4/14
7:20 pm-10:00 pm
1 stop3h 40m
Lambert-St Louis
Tue 4/21
11:30 am-2:00 pm
Nonstop1h 30m
$127
Quickest round-trip
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Mon 4/13
8:10 pm-8:50 pm
Nonstop1h 40m
Lambert-St Louis
Thu 4/16
8:10 pm-10:40 pm
Nonstop1h 30m
$137
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Fri 4/17
8:10 pm-8:50 pm
Nonstop1h 40m
Lambert-St Louis
Fri 4/24
8:10 pm-10:40 pm
Nonstop1h 30m
$137
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Mon 4/13
3:45 pm-11:15 pm
2 stops8h 30m
Lambert-St Louis
Wed 4/15
5:35 am-9:55 am
1 stop3h 20m
$152
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 4/8
8:59 am-9:46 am
Nonstop1h 47m
Lambert-St Louis
Mon 4/13
6:48 am-9:17 am
Nonstop1h 29m
$205
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Mon 6/8
8:15 pm-9:00 pm
Nonstop1h 45m
Lambert-St Louis
Wed 6/10
10:25 am-1:00 pm
Nonstop1h 35m
$217
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 5/28
8:05 pm-8:55 pm
Nonstop1h 50m
Lambert-St Louis
Sat 5/30
6:55 pm-9:30 pm
Nonstop1h 35m
$217
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Mon 4/13
6:55 am-7:45 am
Nonstop1h 50m
Lambert-St Louis
Wed 4/15
3:55 pm-8:45 pm
1 stop3h 50m
$227
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 4/16
8:10 pm-11:15 pm
1 stop4h 05m
Lambert-St Louis
Tue 4/21
10:15 am-12:55 pm
Nonstop1h 40m
$227
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Fri 4/17
5:40 pm-11:14 pm
1 stop6h 34m
Lambert-St Louis
Sun 4/19
6:50 pm-12:34 am
1 stop4h 44m
$228
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Ohio with our price prediction graph.
CLE-STL
DTW-STL
CLE-MCI
CVG-MCI
DTW-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Missouri
USOH-USMO
CLE-STL
DTW-STL
CLE-MCI
CVG-MCI
What is the cheapest month to book a flight from Ohio to Missouri?
Currently, October is the cheapest month in which you can book a flight from Ohio to Missouri (average of $85). Flying from Ohio to Missouri in March is currently the most expensive (average of $210). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to MO?
Find hourly flight availability from Ohio to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 22, 2026.
It’s optimal to fly from Ohio to Missouri in the evening. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight in the afternoon.
What is the cheapest day to fly from Ohio to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Ohio to Missouri. Price data was last updated on March 14, 2026.
Travelers seeking maximum savings on their Ohio to Missouri flight should consider departing on Saturday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 22, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Ohio to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Ohio to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Ohio to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to Missouri by cabin class
Find flights from Ohio to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ohio and Missouri flights
Browse other Ohio and Missouri flight options. Last updated on March 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Ohio after your stay in Missouri
Ohio to Missouri flights
Consider these flights traveling from Ohio to Missouri.
Top 5 airlines flying from Ohio to Missouri
Discover the top 5 airlines that operate flights from Ohio to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$91 | Average$194 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$99 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$171 | Average$347 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$204 | Average$362 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$210 | Average$369 | FlexibilityNo cancel fee | On-time69% |