How long is the flight from Ohio to Missouri?

Airlines like Frontier, Spirit Airlines, and United Airlines fly from Ohio to Missouri in about 5h 41m. The time it takes to get you to your destination can typically vary by up to 17h 38m. Ohio and Missouri are separated by a distance of 439 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Ohio to Missouri one-way?

For one-way options, check prices for Frontier. According to our data, you can fly for as low as $71. Users have also found prices from $84 and $87 on United Airlines and Delta, respectively.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Can I find deals for flights from Ohio to Missouri that include hotel bookings?

Yes. In addition to deals on Ohio to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Ohio to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Missouri.

Can I find deals for business class flights from Ohio to Missouri?

Yes. Cheapflights offers flight deals from Ohio to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$64+ Flights from Ohio to Missouri

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Ohio to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Ohio to Missouri

Cheapest flights from Ohio to Missouri
Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

mié. 12/314:48 pmCLE - STL

1 stop6h 45mFrontier

jue. 1/110:42 amSTL - CLE

1 stop11h 31mFrontier

Deal found 12/14

$208

dom. 12/219:30 pmCLE - STL

1 stop11h 42mFrontier

lun. 12/224:27 pmSTL - CLE

1 stop6h 24mFrontier

Deal found 12/14

$238

jue. 12/257:00 amCLE - STL

1 stop10h 24mFrontier

mié. 12/314:27 pmSTL - CLE

1 stop6h 24mFrontier

Deal found 12/15

$253

mié. 12/2412:03 pmCLE - MCI

1 stop5h 54mDelta

jue. 1/16:30 amMCI - CLE

1 stop3h 53mDelta

Deal found 12/15

$255

dom. 12/217:15 amCVG - MCI

1 stop9h 22mFrontier

lun. 1/511:38 amMCI - CVG

1 stop5h 36mFrontier

Deal found 12/16

$268

mié. 12/246:15 amCLE - MCI

2 stops29h 43mMultiple Airlines

mié. 12/316:15 pmMCI - CLE

1 stop15h 22mMultiple Airlines

Deal found 12/15

$273

mié. 12/314:56 pmDTW - SGF

1 stop5h 23mDelta

mié. 1/75:00 pmSGF - DTW

1 stop5h 42mDelta

Deal found 12/16

$274

sáb. 12/202:05 pmCVG - MCI

1 stop6h 46mFrontier

lun. 12/2211:13 amMCI - CVG

1 stop6h 01mFrontier

Deal found 12/13

$293

mié. 12/174:48 pmCLE - STL

1 stop6h 45mFrontier

vie. 12/199:07 amSTL - CLE

1 stop10h 08mFrontier

Deal found 12/14

$298

jue. 12/1810:01 pmDTW - STL

1 stop13h 01mFrontier

dom. 12/2110:57 amSTL - DTW

1 stop6h 12mFrontier

Deal found 12/15

$298

mar. 12/302:43 pmDTW - MCI

1 stop27h 27mMultiple Airlines

lun. 1/56:15 pmMCI - DTW

2 stops36h 52mMultiple Airlines

Deal found 12/15

$298

jue. 12/256:00 amCLE - MCI

1 stop29h 08mMultiple Airlines

mié. 12/316:15 pmMCI - CLE

1 stop15h 22mMultiple Airlines

Deal found 12/15

$304

Best flights from Ohio to Missouri
Discover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 16, 2025.

jue. 1/87:10 amCLE - STL

1 stop8h 38mFrontier

lun. 1/125:06 pmSTL - CLE

1 stop6h 31mFrontier

Deal found 12/14

$162

jue. 1/225:32 amPIT - STL

1 stop19h 01mMultiple Airlines

lun. 1/268:22 pmSTL - PIT

2 stops36h 18mMultiple Airlines

Deal found 12/14

$179

jue. 1/225:50 pmPIT - MCI

2 stops23h 19mSpirit Airlines

lun. 1/2611:26 amMCI - PIT

1 stop11h 18mSpirit Airlines

Deal found 12/15

$180

jue. 1/226:00 amDTW - STL

1 stop5h 41mUnited Airlines

lun. 1/263:11 pmSTL - DTW

1 stop4h 15mUnited Airlines

Deal found 12/14

$191

mié. 1/147:04 pmPIT - STL

1 stop5h 08mAmerican Airlines

lun. 1/193:54 pmSTL - PIT

1 stop6h 35mAmerican Airlines

Deal found 12/14

$191

mié. 1/146:30 amCLE - STL

1 stop5h 13mDelta

mié. 1/215:25 pmSTL - CLE

1 stop4h 29mDelta

Deal found 12/16

$203

mié. 1/146:40 amCLE - STL

1 stop4h 35mSouthwest

mié. 1/215:55 pmSTL - CLE

Nonstop1h 30mSouthwest

Deal found 12/15

$213

lun. 2/212:08 pmCLE - STL

1 stop12h 25mFrontier

jue. 2/510:01 pmSTL - CLE

1 stop24h 37mFrontier

Deal found 12/15

$162

sáb. 2/2112:29 pmCLE - STL

1 stop12h 30mFrontier

jue. 2/2610:11 pmSTL - CLE

1 stop14h 19mFrontier

Deal found 12/16

$162

vie. 2/207:00 amCLE - MCI

1 stop15h 29mAlaska Airlines

dom. 2/222:49 pmMCI - CLE

1 stop27h 39mAlaska Airlines

Deal found 12/16

$364

mié. 1/147:21 amCLE - MCI

2 stops28h 10mMultiple Airlines

lun. 1/1911:41 amMCI - CLE

1 stop18h 53mMultiple Airlines

Deal found 12/15

$183

jue. 1/1510:49 amPIT - STL

1 stop4h 41mUnited Airlines

lun. 1/196:30 amSTL - PIT

1 stop5h 40mUnited Airlines

Deal found 12/14

$191

sáb. 1/105:42 pmPIT - STL

1 stop6h 02mAmerican Airlines

lun. 1/127:00 amSTL - PIT

1 stop6h 41mAmerican Airlines

Deal found 12/14

$191

lun. 1/125:15 pmDTW - MCI

1 stop23h 54mSpirit Airlines

jue. 1/1511:26 amMCI - DTW

1 stop10h 18mSpirit Airlines

Deal found 12/15

$201

jue. 2/194:27 pmDTW - MCI

2 stops19h 03mMultiple Airlines

dom. 2/221:44 pmMCI - DTW

1 stop9h 11mMultiple Airlines

Deal found 12/16

$188

sáb. 2/216:30 amCLE - STL

1 stop4h 02mDelta

mié. 2/255:50 pmSTL - CLE

1 stop5h 04mDelta

Deal found 12/16

$213

mar. 3/31:55 pmCLE - STL

1 stop9h 32mFrontier

jue. 3/53:49 pmSTL - CLE

1 stop6h 20mFrontier

Deal found 12/14

$183

sáb. 1/178:50 amDTW - STL

Nonstop1h 55mSouthwest

mié. 1/215:55 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 12/16

$222

sáb. 1/175:15 amDTW - STL

1 stop18h 19mMultiple Airlines

mié. 1/218:22 pmSTL - DTW

2 stops15h 49mMultiple Airlines

Deal found 12/16

$194

mar. 1/135:50 amDTW - STL

Nonstop2h 00mSouthwest

sáb. 1/175:45 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 12/13

$237

sáb. 2/216:15 amCLE - STL

1 stop18h 44mMultiple Airlines

mié. 2/258:17 pmSTL - CLE

2 stops16h 46mMultiple Airlines

Deal found 12/16

$197

dom. 2/228:43 pmCLE - STL

1 stop11h 08mFrontier

jue. 2/2610:11 pmSTL - CLE

1 stop14h 19mFrontier

Deal found 12/16

$197

mié. 1/215:50 pmPIT - MCI

1 stop17h 41mSpirit Airlines

sáb. 1/245:04 pmMCI - PIT

1 stop29h 03mSpirit Airlines

Deal found 12/14

$249

jue. 1/85:30 amDTW - STL

1 stop6h 32mUnited Airlines

lun. 1/123:11 pmSTL - DTW

1 stop4h 15mUnited Airlines

Deal found 12/14

$251

dom. 2/85:07 pmCVG - MCI

1 stop18h 24mMultiple Airlines

dom. 2/1511:26 amMCI - CVG

1 stop23h 09mMultiple Airlines

Deal found 12/14

$201

dom. 5/246:00 amCLE - SGF

1 stop6h 07mDelta

sáb. 5/304:00 pmSGF - CLE

1 stop7h 37mDelta

Deal found 12/16

$269

mié. 1/148:19 amCLE - SGF

1 stop4h 30mAmerican Airlines

mié. 1/2112:26 pmSGF - CLE

1 stop5h 36mAmerican Airlines

Deal found 12/15

$269

mié. 1/74:05 pmDTW - STL

1 stop6h 50mSouthwest

sáb. 1/315:45 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 12/14

$247

mié. 12/314:48 pmCLE - STL

1 stop6h 45mFrontier

jue. 1/110:42 amSTL - CLE

1 stop11h 31mFrontier

Deal found 12/13

$208

sáb. 1/242:57 pmPIT - STL

1 stop5h 30mUnited Airlines

lun. 1/264:49 pmSTL - PIT

1 stop5h 55mUnited Airlines

Deal found 12/13

$261

Last-minute flights from Ohio to Missouri
Discover last-minute flight deals from Ohio to Missouri. Data last updated diciembre 16, 2025 and is based on user searches.

mar. 1/68:20 pmCLE - STL

1 stop14h 42mFrontier

mar. 1/135:11 pmSTL - CLE

1 stop22h 56mFrontier

Deal found 12/15

$133

mié. 1/77:22 pmDTW - STL

1 stop28h 11mMultiple Airlines

sáb. 1/318:22 pmSTL - DTW

1 stop14h 49mMultiple Airlines

Deal found 12/14

$170

jue. 1/84:53 pmCLE - STL

1 stop6h 40mFrontier

lun. 1/125:06 pmSTL - CLE

1 stop6h 31mFrontier

Deal found 12/15

$162

lun. 1/125:15 pmDTW - STL

1 stop30h 19mMultiple Airlines

lun. 1/195:11 pmSTL - DTW

1 stop16h 43mMultiple Airlines

Deal found 12/15

$156

mar. 1/132:36 pmDTW - STL

1 stop17h 15mMultiple Airlines

sáb. 1/178:32 pmSTL - DTW

1 stop16h 45mMultiple Airlines

Deal found 12/13

$154

mar. 1/136:00 amPIT - STL

2 stops25h 51mMultiple Airlines

mar. 1/205:42 pmSTL - PIT

1 stop28h 25mMultiple Airlines

Deal found 12/14

$172

mié. 1/144:50 pmCLE - STL

1 stop20h 50mFrontier

mié. 1/218:22 pmSTL - CLE

1 stop10h 12mFrontier

Deal found 12/15

$145

jue. 1/153:12 pmDTW - MCI

1 stop20h 19mMultiple Airlines

dom. 1/188:27 pmMCI - DTW

1 stop13h 57mMultiple Airlines

Deal found 12/16

$167

jue. 1/155:32 amPIT - STL

1 stop18h 02mMultiple Airlines

lun. 1/198:32 pmSTL - PIT

2 stops26h 12mMultiple Airlines

Deal found 12/14

$171

jue. 1/225:50 pmPIT - MCI

1 stop17h 41mSpirit Airlines

lun. 1/2611:26 amMCI - PIT

1 stop21h 14mSpirit Airlines

Deal found 12/15

$151

jue. 1/227:14 pmDTW - STL

1 stop12h 37mMultiple Airlines

lun. 1/268:22 pmSTL - DTW

1 stop16h 08mMultiple Airlines

Deal found 12/14

$166

mié. 1/285:15 pmDTW - STL

1 stop7h 18mMultiple Airlines

mié. 2/48:22 pmSTL - DTW

1 stop12h 58mMultiple Airlines

Deal found 12/14

$157

One-way flights from Ohio to Missouri
Search for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated diciembre 16, 2025.

mié. 2/119:35 amDTW - STL

1 stop7h 18mFrontier

Deal found 12/15

$64

mié. 2/119:35 amDTW - MCI

1 stop7h 09mFrontier

Deal found 12/15

$64

mar. 1/137:10 amCLE - STL

1 stop24h 41mFrontier

Deal found 12/16

$68

mié. 2/258:48 pmDTW - STL

1 stop28h 11mFrontier

Deal found 12/14

$68

lun. 2/91:45 pmCVG - MCI

1 stop7h 06mFrontier

Deal found 12/14

$69

mar. 2/108:46 pmCLE - STL

1 stop11h 05mFrontier

Deal found 12/14

$70

mar. 2/108:48 pmDTW - STL

1 stop26h 39mFrontier

Deal found 12/15

$70

mar. 1/1311:00 amDTW - STL

1 stop20h 51mMultiple Airlines

Deal found 12/16

$76

dom. 2/85:07 pmCVG - MCI

1 stop18h 24mMultiple Airlines

Deal found 12/16

$77

dom. 2/81:43 pmDTW - MCI

1 stop21h 48mMultiple Airlines

Deal found 12/15

$77

vie. 1/2311:53 amCLE - STL

1 stop12h 40mFrontier

Deal found 12/15

$78

vie. 1/237:14 pmDTW - STL

1 stop12h 37mFrontier

Deal found 12/15

$78

Find flight deals from Ohio to Missouri

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$133 (Kiwi.com)
One-way from	$64 (Expedia)
Popular in	January
Cheapest in	August
Average price	$336
Good round-trip deal	$306 or less
Good one-way deal	$194 or less

Provider with most accurate pricing for Cleveland Hopkins Intl-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Lambert-St Louis flights.

Search Deals

From Ohio to Missouri

Search Deals

One-way flight from Ohio to Missouri

Search Deals

Highest demand for flights based on searches. 13% potential increase in price ($48 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Ohio to Missouri.

Search Deals

Price to beat on a one-way flight from Ohio to Missouri.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

jue. 1/8

7:10 am-2:48 pm

1 stop8h 38m

Lambert-St Louis

lun. 1/12

5:06 pm-12:37 am

1 stop6h 31m

$162

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

lun. 2/2

12:08 pm-11:33 pm

1 stop12h 25m

Lambert-St Louis

jue. 2/5

10:01 pm-11:38 pm

1 stop24h 37m

$162

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

sáb. 2/21

12:29 pm-11:59 pm

1 stop12h 30m

Lambert-St Louis

jue. 2/26

10:11 pm-1:30 pm

1 stop14h 19m

$162

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

jue. 1/22

5:32 am-11:33 pm

1 stop19h 01m

Lambert-St Louis

lun. 1/26

8:22 pm-9:40 am

2 stops36h 18m

$179

PittsburghKansas City

PIT - MCI

PITMCI

Pittsburgh

jue. 1/22

5:50 pm-4:09 pm

2 stops23h 19m

Kansas City

lun. 1/26

11:26 am-11:44 pm

1 stop11h 18m

$180

ClevelandKansas City

CLE - MCI

CLEMCI

Cleveland Hopkins Intl

mié. 1/14

7:21 am-10:31 am

2 stops28h 10m

Kansas City

lun. 1/19

11:41 am-7:34 am

1 stop18h 53m

$183

ClevelandSt. Louis

CLE - STL

CLESTL

Cleveland Hopkins Intl

mar. 3/3

1:55 pm-10:27 pm

1 stop9h 32m

Lambert-St Louis

jue. 3/5

3:49 pm-11:09 pm

1 stop6h 20m

$183

DetroitKansas City

DTW - MCI

DTWMCI

Detroit Metropolitan Wayne County

jue. 2/19

4:27 pm-10:30 am

2 stops19h 03m

Kansas City

dom. 2/22

1:44 pm-11:55 pm

1 stop9h 11m

$188

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

jue. 1/22

6:00 am-10:41 am

1 stop5h 41m

Lambert-St Louis

lun. 1/26

3:11 pm-8:26 pm

1 stop4h 15m

$191

PittsburghSt. Louis

PIT - STL

PITSTL

Pittsburgh

mié. 1/14

7:04 pm-11:12 pm

1 stop5h 08m

Lambert-St Louis

lun. 1/19

3:54 pm-11:29 pm

1 stop6h 35m

$191

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 60 results

...

Best time to book a flight from Ohio to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Ohio with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Missouri

What is the cheapest month to book a flight from Ohio to Missouri?

Currently, October is the cheapest month in which you can book a flight from Ohio to Missouri (average of $85). Flying from Ohio to Missouri in February is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to MO?

It’s optimal to fly from Ohio to Missouri in the evening. By choosing this option you can save up to 10% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Ohio to Missouri?

Travelers seeking maximum savings on their Ohio to Missouri flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

See what other customers who have flown with Southwest, Delta, and United Airlines from Ohio to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,092 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,049 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.8

Fair

3,082 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How long is the flight from Ohio to Missouri?
Airlines like Frontier, Spirit Airlines, and United Airlines fly from Ohio to Missouri in about 5h 41m. The time it takes to get you to your destination can typically vary by up to 17h 38m. Ohio and Missouri are separated by a distance of 439 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Ohio to Missouri one-way?
For one-way options, check prices for Frontier. According to our data, you can fly for as low as $71. Users have also found prices from $84 and $87 on United Airlines and Delta, respectively.
Can I find deals for flights from Ohio to Missouri that include hotel bookings?
Yes. In addition to deals on Ohio to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Ohio to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Missouri.
Can I find deals for business class flights from Ohio to Missouri?
Yes. Cheapflights offers flight deals from Ohio to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Ohio to Missouri?
Currently, October is the cheapest month in which you can book a flight from Ohio to Missouri (average of $85). Flying from Ohio to Missouri in February is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Ohio to Missouri

John F Kennedy Intl to Miami flights

Newark to Fort Lauderdale flights

Newark to Miami flights

LaGuardia to Fort Lauderdale flights

LaGuardia to Miami flights

John F Kennedy Intl to Fort Lauderdale flights

Dallas/Fort Worth to John F Kennedy Intl flights

John F Kennedy Intl to Orlando flights

John F Kennedy Intl to Las Vegas flights

John F Kennedy Intl to Los Angeles flights

Los Angeles to John F Kennedy Intl flights

Newark to West Palm Beach flights

Newark to Orlando flights

Dallas/Fort Worth to LaGuardia flights

Dallas/Fort Worth to Newark flights

John F Kennedy Intl to Dallas/Fort Worth flights

LaGuardia to Orlando flights

Los Angeles to Newark flights

Newark to Las Vegas flights

Newark to Los Angeles flights

John F Kennedy Intl to West Palm Beach flights

O'Hare Intl to John F Kennedy Intl flights

O'Hare Intl to Las Vegas flights

O'Hare Intl to Dallas/Fort Worth flights

Minneapolis to Sky Harbor Intl flights

Dallas/Fort Worth to Las Vegas flights

Baltimore to Fort Lauderdale flights

LaGuardia to Dallas/Fort Worth flights

San Francisco to Las Vegas flights

John F Kennedy Intl to Tampa flights

Seattle to Los Angeles flights

Dallas/Fort Worth to Seattle flights

Seattle to Dallas/Fort Worth flights

Newark to Dallas/Fort Worth flights

Los Angeles to Seattle flights

Atlanta to John F Kennedy Intl flights

Seattle to Las Vegas flights

Los Angeles to Honolulu flights

Reagan-National to Miami flights

Dulles Intl to Miami flights

Newark to Tampa flights

San Francisco to John F Kennedy Intl flights

John F Kennedy Intl to Atlanta flights

O'Hare Intl to Fort Lauderdale flights

Dallas/Fort Worth to Orlando flights

John F Kennedy Intl to San Francisco flights

Atlanta to LaGuardia flights

Boston to Fort Lauderdale flights

Dallas/Fort Worth to Denver flights

Boston to Miami flights

Complete your trip

Missouri car rentals

Kansas City Airport car rentals

Lambert-St Louis Airport car rentals

Springfield-Branson Airport car rentals

Columbia Regional Airport car rentals

Joplin Airport car rentals

Cape Girardeau Airport car rentals

Fort Leonard Wood Waynesville Regional Airport car rentals

Kirksville Cannon Memorial Airport car rentals

St. Louis car rentals

Kansas City car rentals

Springfield car rentals

Find a return flight route from Missouri

Ohio to Missouri flights

Detroit to St. Louis flights

Pittsburgh to Kansas City flights

Detroit to Kansas City flights

Cincinnati to Kansas City flights

Cleveland to St. Louis flights

Columbus to Kansas City flights

Pittsburgh to St. Louis flights

Cleveland to Kansas City flights

Detroit to Springfield flights

Cleveland to Springfield flights

Cincinnati to St. Louis flights

Columbus to St. Louis flights

Akron to Kansas City flights

Pittsburgh to Springfield flights

Dayton to Kansas City flights

Dayton to Springfield flights

Akron to St. Louis flights

Dayton to St. Louis flights

Akron to Springfield flights

Detroit to Columbia flights

Detroit to Joplin flights

Cincinnati to Springfield flights

Dayton to Columbia flights

Columbus to Springfield flights

Huntington to Kansas City flights

Pittsburgh to Joplin flights

Dayton to Quincy flights

Toledo to St. Louis flights

Toledo to Springfield flights

Toledo to Kansas City flights

Toledo to Columbia flights

Huntington to Springfield flights

Erie to St. Louis flights

Erie to Joplin flights

Detroit to Branson flights

Top 5 airlines flying from Ohio to Missouri

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$85	Average$252	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$121	Average$356	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$186	Average$355	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$205	Average$353	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$213	Average$374	FlexibilityNo cancel fee	On-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$64+ Cheap flights from Ohio to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Ohio to Missouri with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Ohio to Missouri

Cheapest flights from Ohio to MissouriExplore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

Find flight deals from Ohio to Missouri

Keep the following information in mind while searching for Ohio to Missouri flight deals. Data was last updated diciembre 16, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Ohio to Missouri that are best for you.

Best time to book a flight from Ohio to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Ohio with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Missouri

What is the cheapest month to book a flight from Ohio to Missouri?

What is the cheapest time of day to fly from OH to MO?

Find hourly flight availability from Ohio to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 16, 2025.

What is the cheapest day to fly from Ohio to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Ohio to Missouri. Price data was last updated on December 16, 2024.

Reviews of airlines servicing Missouri

See what other customers who have flown with Southwest, Delta, and United Airlines from Ohio to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Ohio to Missouri?

What are the cheapest airlines to fly from Ohio to Missouri one-way?

Can I find deals for flights from Ohio to Missouri that include hotel bookings?

How can I find direct flights from Ohio to Missouri?

Can I find deals for business class flights from Ohio to Missouri?

What is the cheapest month to book a flight from Ohio to Missouri?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Ohio to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Ohio to Missouri

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Ohio to Missouri
Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.