$59+ Cheap flights from Ohio to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — STL
Jun 3 — Jun 101
Round-trip
1 adult, Economy
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Cheapest flights from Ohio to MissouriExplore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:46 pm
CVG
- MCI
1 stop5h 43m
Frontier
Fri 6/56:24 pm
MCI
- CVG
1 stop16h 17m
Frontier
Deal found 4/30![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/318:46 pm
CLE
- STL
1 stop13h 09m
Frontier
Sun 6/76:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Deal found 5/3![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:54 am
CLE
- MCI
1 stop11h 35m
Frontier
Wed 6/106:16 pm
MCI
- CLE
1 stop13h 37m
Frontier
Deal found 5/1![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:30 am
CLE
- STL
1 stop11h 03m
Frontier
Thu 6/46:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Deal found 5/1![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 am
DTW
- STL
1 stop11h 43m
Frontier
Sun 6/76:33 pm
STL
- DTW
1 stop5h 05m
Frontier
Deal found 5/4![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:54 am
CLE
- MCI
1 stop11h 35m
Frontier
Sat 6/136:16 pm
MCI
- CLE
1 stop13h 37m
Frontier
Deal found 4/30![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Wed 6/106:16 pm
MCI
- DTW
1 stop17h 51m
Frontier
Deal found 5/4![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:49 pm
CLE
- STL
1 stop13h 06m
Frontier
Tue 6/96:31 pm
STL
- CLE
1 stop16h 21m
Frontier
Deal found 5/4![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:02 pm
DTW
- STL
1 stop19h 55m
Frontier
Tue 8/116:33 pm
STL
- DTW
1 stop21h 17m
Frontier
Deal found 5/3![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/253:46 pm
CLE
- MCI
1 stop26h 35m
Frontier
Sat 6/276:16 pm
MCI
- CLE
1 stop13h 37m
Frontier
Deal found 5/1![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:46 pm
CLE
- STL
1 stop26h 47m
Frontier
Thu 6/46:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Deal found 5/1![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/1![Frontier logo]()
$132
Best flights from Ohio to MissouriDiscover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
Discover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:20 pm
CLE
- STL
1 stop3h 40m
Southwest
Thu 6/48:55 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 5/1![Southwest logo]()
$174
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:31 pm
DTW
- STL
Nonstop1h 39m
Delta
Tue 6/96:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/3![Delta logo]()
$197
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:05 pm
PIT
- STL
1 stop4h 23m
United Airlines
Sat 5/305:29 pm
STL
- PIT
1 stop5h 30m
United Airlines
Deal found 5/2![United Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:38 pm
CLE
- SGF
1 stop8h 08m
American Airlines
Sat 5/233:56 pm
SGF
- CLE
1 stop5h 36m
American Airlines
Deal found 5/3![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:10 pm
CLE
- STL
Nonstop1h 40m
Southwest
Thu 6/45:40 am
STL
- CLE
1 stop3h 30m
Southwest
Deal found 5/4![Southwest logo]()
$201
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:20 am
DTW
- STL
Nonstop1h 40m
Southwest
Mon 5/257:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/1![Southwest logo]()
$213
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:30 pm
DTW
- STL
Nonstop1h 39m
Delta
Mon 6/86:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 4/29![Delta logo]()
$245
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:20 pm
PIT
- STL
1 stop6h 15m
United Airlines
Sat 5/307:05 pm
STL
- PIT
1 stop3h 54m
United Airlines
Deal found 4/29![United Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:45 pm
CLE
- STL
2 stops6h 00m
Southwest
Mon 6/85:35 pm
STL
- CLE
1 stop4h 25m
Southwest
Deal found 5/3![Southwest logo]()
$216
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:45 am
DTW
- STL
Nonstop1h 44m
Delta
Mon 6/111:25 am
STL
- DTW
1 stop6h 10m
Delta
Deal found 4/30![Delta logo]()
$255
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:40 pm
CLE
- STL
Nonstop1h 40m
Southwest
Fri 6/55:40 am
STL
- CLE
1 stop3h 30m
Southwest
Deal found 5/1![Southwest logo]()
$218
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:51 am
PIT
- STL
1 stop4h 20m
United Airlines
Wed 6/36:00 am
STL
- PIT
1 stop6h 11m
United Airlines
Deal found 5/3![United Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:20 pm
PIT
- STL
1 stop6h 36m
Delta
Mon 6/2910:20 am
STL
- PIT
1 stop4h 20m
Delta
Deal found 4/29![Delta logo]()
$280
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:10 pm
CLE
- STL
1 stop4h 15m
Southwest
Fri 7/33:35 pm
STL
- CLE
2 stops7h 40m
Southwest
Deal found 4/30![Southwest logo]()
$233
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Wed 6/36:00 am
STL
- DTW
2 stops7h 34m
United Airlines
Deal found 5/1![United Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:00 am
CLE
- SGF
1 stop5h 29m
American Airlines
Sun 5/247:39 pm
SGF
- CLE
1 stop12h 39m
American Airlines
Deal found 4/29![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:07 pm
CVG
- MCI
1 stop3h 50m
Delta
Sat 5/306:30 am
MCI
- CVG
1 stop5h 57m
Delta
Deal found 4/29![Delta logo]()
$282
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:40 pm
DTW
- STL
2 stops8h 20m
Southwest
Tue 6/22:30 pm
STL
- DTW
2 stops7h 00m
Southwest
Deal found 5/1![Southwest logo]()
$235
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:05 am
DTW
- STL
1 stop5h 41m
United Airlines
Wed 5/271:13 pm
STL
- DTW
2 stops9h 18m
United Airlines
Deal found 5/2![United Airlines logo]()
$286
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:45 am
DTW
- STL
Nonstop1h 44m
Delta
Sun 6/76:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/4![Delta logo]()
$287
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:30 am
CLE
- STL
1 stop4h 07m
United Airlines
Sun 10/46:49 pm
STL
- CLE
1 stop4h 09m
United Airlines
Deal found 4/29![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:55 am
PIT
- STL
Nonstop1h 50m
Southwest
Thu 6/410:05 am
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 4/30![Southwest logo]()
$265
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:25 am
PIT
- STL
1 stop3h 40m
Delta
Fri 7/246:04 pm
STL
- PIT
1 stop5h 00m
Delta
Deal found 4/29![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:08 pm
PIT
- STL
1 stop4h 15m
United Airlines
Sun 5/2410:25 am
STL
- PIT
1 stop5h 45m
United Airlines
Deal found 5/2![United Airlines logo]()
$306
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:05 pm
PIT
- STL
Nonstop1h 50m
Southwest
Thu 6/410:05 am
STL
- PIT
Nonstop1h 35m
Southwest
Deal found 5/1![Southwest logo]()
$265
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:18 am
CLE
- STL
1 stop5h 51m
Delta
Sun 6/286:30 am
STL
- CLE
1 stop6h 16m
Delta
Deal found 5/1![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:35 am
DTW
- STL
2 stops7h 25m
Southwest
Wed 6/31:45 pm
STL
- DTW
2 stops7h 45m
Southwest
Deal found 4/29![Southwest logo]()
$267
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2610:25 am
PIT
- STL
1 stop3h 44m
Delta
Fri 7/310:20 am
STL
- PIT
1 stop4h 20m
Delta
Deal found 5/3![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
CLE
- SGF
2 stops9h 35m
United Airlines
Sat 5/236:35 pm
SGF
- CLE
1 stop4h 23m
United Airlines
Deal found 5/3![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:10 pm
CLE
- STL
Nonstop1h 40m
Southwest
Mon 6/18:10 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 5/2![Southwest logo]()
$274
Last-minute flights from Ohio to MissouriDiscover last-minute flight deals from Ohio to Missouri. Data last updated May 4, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Missouri. Data last updated May 4, 2026 and is based on user searches.
This Travelocity deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:55 am
DTW
- STL
1 stop12h 28m
Frontier
Tue 5/268:08 pm
STL
- DTW
1 stop15h 27m
Frontier
Deal found 4/30![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:50 am
DTW
- STL
1 stop11h 43m
Frontier
Mon 6/15:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/4![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/1![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/318:46 pm
CLE
- STL
1 stop13h 09m
Frontier
Sun 6/76:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Deal found 5/3![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:46 pm
CLE
- STL
1 stop26h 47m
Frontier
Thu 6/46:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Deal found 5/1![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:30 am
CLE
- STL
1 stop11h 03m
Frontier
Thu 6/46:33 pm
STL
- CLE
1 stop16h 17m
Frontier
Deal found 5/1![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:49 pm
CLE
- STL
1 stop13h 06m
Frontier
Tue 6/96:31 pm
STL
- CLE
1 stop16h 21m
Frontier
Deal found 5/4![Frontier logo]()
$126
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:40 pm
CLE
- STL
Nonstop1h 40m
Southwest
Tue 6/97:15 pm
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 5/4![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:46 pm
CVG
- MCI
1 stop5h 43m
Frontier
Fri 6/56:24 pm
MCI
- CVG
1 stop16h 17m
Frontier
Deal found 4/30![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Wed 6/106:16 pm
MCI
- DTW
1 stop17h 51m
Frontier
Deal found 5/4![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 am
DTW
- STL
1 stop11h 43m
Frontier
Sun 6/76:33 pm
STL
- DTW
1 stop5h 05m
Frontier
Deal found 5/4![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:30 am
DTW
- STL
1 stop12h 03m
Multiple Airlines
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$137
One-way flights from Ohio to MissouriSearch for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
Search for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
This Trip.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:30 am
CLE
- STL
1 stop26h 25m
Frontier
Deal found 4/30![Frontier logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:24 pm
CLE
- STL
1 stop14h 28m
Frontier
Deal found 5/4![Frontier logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:24 pm
CLE
- STL
1 stop14h 31m
Frontier
Deal found 5/4![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Deal found 5/4![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:05 pm
CMH
- STL
1 stop15h 50m
Frontier
Deal found 5/1![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:24 pm
CLE
- STL
1 stop23h 06m
Frontier
Deal found 4/30![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 pm
CMH
- MCI
1 stop24h 21m
Frontier
Deal found 4/29![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:49 pm
CLE
- MCI
1 stop21h 40m
Frontier
Deal found 4/30![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:59 pm
DTW
- MCI
1 stop28h 30m
Frontier
Deal found 5/4![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 pm
CMH
- STL
1 stop15h 52m
Frontier
Deal found 5/1![Frontier logo]()
$65
This Trip.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/78:46 pm
CLE
- STL
1 stop13h 09m
Frontier
Deal found 4/29![Frontier logo]()
$66
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:05 am
CLE
- STL
Nonstop1h 40m
Southwest
Deal found 4/30![Southwest logo]()
$69
Find flight deals from Ohio to Missouri
Keep the following information in mind while searching for Ohio to Missouri flight deals. Data was last updated May 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $121 (Kiwi.com) |
One-way from | $59 (Trip.com) |
Popular in | January |
Cheapest in | August |
Average price | $298 |
Good round-trip deal | $383 or less |
Good one-way deal | $179 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Ohio to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 6/2
7:20 pm-10:00 pm
1 stop3h 40m
Lambert-St Louis
Thu 6/4
8:55 pm-11:25 pm
Nonstop1h 30m
$174
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 6/2
12:31 pm-1:10 pm
Nonstop1h 39m
Lambert-St Louis
Tue 6/9
6:30 am-9:04 am
Nonstop1h 34m
$197
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 5/28
2:05 pm-5:28 pm
1 stop4h 23m
Lambert-St Louis
Sat 5/30
5:29 pm-11:59 pm
1 stop5h 30m
$197
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Mon 6/1
8:10 pm-8:50 pm
Nonstop1h 40m
Lambert-St Louis
Thu 6/4
5:40 am-10:10 am
1 stop3h 30m
$201
Quickest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 5/23
7:20 am-8:00 am
Nonstop1h 40m
Lambert-St Louis
Mon 5/25
7:40 pm-10:10 pm
Nonstop1h 30m
$213
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Thu 6/4
5:45 pm-10:45 pm
2 stops6h 00m
Lambert-St Louis
Mon 6/8
5:35 pm-11:00 pm
1 stop4h 25m
$216
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 6/2
7:40 pm-8:20 pm
Nonstop1h 40m
Lambert-St Louis
Fri 6/5
5:40 am-10:10 am
1 stop3h 30m
$218
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Wed 7/1
7:10 pm-10:25 pm
1 stop4h 15m
Lambert-St Louis
Fri 7/3
3:35 pm-12:15 am
2 stops7h 40m
$233
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 5/27
12:40 pm-8:00 pm
2 stops8h 20m
Lambert-St Louis
Tue 6/2
2:30 pm-10:30 pm
2 stops7h 00m
$235
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 6/5
8:30 pm-9:09 pm
Nonstop1h 39m
Lambert-St Louis
Mon 6/8
6:30 am-9:04 am
Nonstop1h 34m
$245
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Ohio with our price prediction graph.
CLE-STL
CVG-MCI
DTW-STL
DTW-MCI
CLE-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Missouri
USOH-USMO
CLE-STL
CVG-MCI
DTW-STL
DTW-MCI
How far ahead should I book a flight from Ohio to Missouri?
To ensure you get the cheapest price possible for a flight from Ohio to Missouri, you should look to book at least 89 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Ohio to Missouri?
Currently, October is the cheapest month in which you can book a flight from Ohio to Missouri (average of $85). Flying from Ohio to Missouri in December is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to MO?
Find hourly flight availability from Ohio to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 4, 2026.
It’s optimal to fly from Ohio to Missouri in the evening. By choosing this option you can save up to 20% on the cost of your flight, compared to a flight in the afternoon.
What is the cheapest day to fly from Ohio to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Ohio to Missouri. Price data was last updated on May 2, 2026.
Travelers seeking maximum savings on their Ohio to Missouri flight should consider departing on Saturday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Ohio to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 4, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Ohio to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Ohio to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Ohio to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to Missouri by cabin class
Find flights from Ohio to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ohio and Missouri flights
Browse other Ohio and Missouri flight options. Last updated on May 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Ohio after your stay in Missouri
Ohio to Missouri flights
Consider these flights traveling from Ohio to Missouri.
Top 5 airlines flying from Ohio to Missouri
Discover the top 5 airlines that operate flights from Ohio to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$85 | Average$208 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$99 | Average$354 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$185 | Average$354 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$186 | Average$382 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$210 | Average$373 | FlexibilityNo cancel fee | On-time69% |