$54+ Cheap flights from Ohio to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — STL
Mar 5 — Mar 121
1 adult, Economy
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Find cheap flights from Ohio to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Ohio to MissouriExplore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/202:40 pm
CLE
- STL
1 stop17h 11m
Frontier
Mon 2/238:22 pm
STL
- CLE
1 stop10h 12m
Frontier
Deal found 2/2![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:30 am
DTW
- MCI
1 stop8h 14m
Frontier
Mon 3/98:38 pm
MCI
- DTW
1 stop13h 21m
Frontier
Deal found 2/1![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/82:51 pm
CMH
- STL
1 stop23h 28m
Frontier
Mon 3/2312:16 pm
STL
- CMH
1 stop22h 26m
Frontier
Deal found 2/3![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:07 pm
DTW
- STL
1 stop21h 27m
Frontier
Wed 3/1811:32 am
STL
- DTW
1 stop19h 35m
Frontier
Deal found 2/2![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/101:07 pm
CMH
- STL
1 stop22h 30m
Frontier
Mon 3/2312:16 pm
STL
- CMH
1 stop22h 26m
Frontier
Deal found 2/3![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:33 pm
DTW
- STL
1 stop19h 16m
Frontier
Mon 3/92:09 pm
STL
- DTW
1 stop16h 58m
Frontier
Deal found 2/3![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Mon 3/92:09 pm
STL
- DTW
1 stop16h 58m
Frontier
Deal found 2/2![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/202:40 pm
CLE
- STL
1 stop17h 11m
Multiple Airlines
Mon 2/238:22 pm
STL
- CLE
2 stops20h 47m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:35 pm
DTW
- STL
1 stop17h 16m
Multiple Airlines
Fri 2/278:22 pm
STL
- DTW
1 stop16h 08m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/32:35 pm
DTW
- STL
1 stop17h 16m
Multiple Airlines
Fri 3/61:09 pm
STL
- DTW
1 stop18h 38m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$147
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/234:02 pm
CLE
- STL
1 stop8h 57m
Frontier
Thu 2/2610:11 pm
STL
- CLE
1 stop14h 39m
Frontier
Deal found 2/2![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:29 pm
DTW
- STL
1 stop9h 22m
Multiple Airlines
Mon 2/238:22 pm
STL
- DTW
1 stop16h 08m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$151
Best flights from Ohio to MissouriDiscover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:00 am
PIT
- STL
1 stop6h 05m
Southwest
Sat 4/115:35 pm
STL
- PIT
1 stop4h 25m
Southwest
Deal found 2/1![Southwest logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1511:17 am
CMH
- STL
1 stop20h 34m
Multiple Airlines
Mon 2/168:22 pm
STL
- CMH
2 stops26h 10m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:53 pm
CMH
- STL
1 stop28h 34m
Frontier
Fri 2/278:22 pm
STL
- CMH
2 stops12h 43m
Frontier
Deal found 2/1![Frontier logo]()
$180
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:30 am
PIT
- STL
1 stop4h 33m
American Airlines
Sat 4/118:00 am
STL
- PIT
1 stop7h 48m
American Airlines
Deal found 2/1![American Airlines logo]()
$185
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:40 pm
CLE
- STL
1 stop4h 54m
Delta
Sat 4/181:03 pm
STL
- CLE
1 stop4h 40m
Delta
Deal found 2/1![Delta logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:15 am
CMH
- MCI
1 stop29h 15m
Spirit Airlines
Fri 2/2711:26 am
MCI
- CMH
1 stop22h 18m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$204
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:35 am
CVG
- STL
1 stop8h 27m
United Airlines
Wed 2/257:41 am
STL
- CVG
1 stop4h 36m
United Airlines
Deal found 1/31![United Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/156:02 pm
DTW
- STL
1 stop13h 49m
Multiple Airlines
Wed 2/188:17 pm
STL
- DTW
2 stops22h 23m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$184
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:40 pm
CLE
- STL
1 stop4h 54m
Delta
Tue 4/216:48 am
STL
- CLE
1 stop5h 47m
Delta
Deal found 2/1![Delta logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:15 am
CLE
- MCI
2 stops11h 44m
Frontier
Sun 2/2210:14 am
MCI
- CLE
1 stop12h 11m
Frontier
Deal found 2/1![Frontier logo]()
$199
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:35 am
CLE
- STL
1 stop6h 04m
Delta
Wed 4/226:00 am
STL
- CLE
1 stop5h 48m
Delta
Deal found 2/1![Delta logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:07 pm
CVG
- STL
1 stop18h 44m
Frontier
Fri 2/201:59 pm
STL
- CVG
1 stop8h 43m
Frontier
Deal found 2/1![Frontier logo]()
$200
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:15 pm
DTW
- STL
Nonstop1h 40m
Southwest
Mon 5/42:10 pm
STL
- DTW
1 stop4h 25m
Southwest
Deal found 2/1![Southwest logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/261:07 pm
CVG
- MCI
1 stop21h 49m
Multiple Airlines
Fri 2/274:24 pm
MCI
- CVG
1 stop7h 35m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$221
This Frontier deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:31 pm
CLE
- STL
1 stop7h 48m
Frontier
Wed 4/228:13 pm
STL
- CLE
1 stop10h 31m
Frontier
Deal found 2/1![Frontier logo]()
$202
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:30 pm
DTW
- STL
1 stop3h 15m
Southwest
Thu 5/77:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/2![Southwest logo]()
$225
This Cheapflightsfares deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:45 am
CMH
- MCI
1 stop10h 44m
Spirit Airlines
Mon 3/911:26 am
MCI
- CMH
1 stop11h 06m
Spirit Airlines
Deal found 2/3![Spirit Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:04 am
DTW
- SGF
1 stop6h 25m
American Airlines
Tue 4/216:05 pm
SGF
- DTW
1 stop4h 20m
American Airlines
Deal found 2/1![American Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:25 am
CLE
- STL
1 stop4h 17m
Delta
Thu 4/166:50 pm
STL
- CLE
1 stop4h 44m
Delta
Deal found 2/1![Delta logo]()
$225
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:40 pm
DTW
- SGF
2 stops8h 19m
United Airlines
Wed 3/41:25 pm
SGF
- DTW
1 stop8h 06m
United Airlines
Deal found 2/2![United Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:46 pm
CLE
- MCI
2 stops19h 58m
Multiple Airlines
Thu 3/54:24 pm
MCI
- CLE
1 stop14h 18m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$233
This Frontier deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/143:20 pm
CVG
- STL
1 stop9h 39m
Frontier
Fri 2/201:59 pm
STL
- CVG
1 stop8h 43m
Frontier
Deal found 2/1![Frontier logo]()
$216
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
DTW
- SGF
1 stop6h 04m
American Airlines
Sat 5/26:24 pm
SGF
- DTW
1 stop5h 01m
American Airlines
Deal found 2/1![American Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:31 pm
CLE
- MCI
1 stop17h 58m
Spirit Airlines
Sun 3/2912:24 pm
MCI
- CLE
1 stop27h 49m
Spirit Airlines
Deal found 2/1![Spirit Airlines logo]()
$270
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:10 pm
CLE
- STL
Nonstop1h 40m
Southwest
Thu 5/710:30 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 2/1![Southwest logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:07 pm
CVG
- MCI
1 stop21h 56m
Frontier
Sun 2/2210:14 am
MCI
- CVG
1 stop6h 18m
Frontier
Deal found 2/2![Frontier logo]()
$223
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:30 am
CLE
- STL
1 stop4h 16m
Delta
Sat 4/46:32 am
STL
- CLE
1 stop5h 45m
Delta
Deal found 2/2![Delta logo]()
$250
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2812:55 pm
CVG
- MCI
1 stop7h 32m
American Airlines
Sat 3/712:00 pm
MCI
- CVG
1 stop8h 51m
American Airlines
Deal found 2/1![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:00 am
DTW
- SGF
1 stop6h 38m
United Airlines
Tue 3/171:27 pm
SGF
- DTW
2 stops9h 07m
United Airlines
Deal found 2/2![United Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/261:07 pm
CVG
- MCI
1 stop21h 49m
Multiple Airlines
Fri 3/2712:24 pm
MCI
- CVG
2 stops22h 30m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$260
Last-minute flights from Ohio to MissouriDiscover last-minute flight deals from Ohio to Missouri. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Missouri. Data last updated February 3, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/178:46 pm
CLE
- STL
1 stop11h 05m
Frontier
Thu 2/193:49 pm
STL
- CLE
1 stop6h 20m
Frontier
Deal found 2/2![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:46 pm
CLE
- MCI
1 stop14h 17m
Frontier
Sun 2/2210:14 am
MCI
- CLE
1 stop12h 11m
Frontier
Deal found 2/1![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/202:40 pm
CLE
- STL
1 stop17h 11m
Frontier
Mon 2/238:22 pm
STL
- CLE
1 stop10h 12m
Frontier
Deal found 2/2![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/202:40 pm
CLE
- STL
1 stop17h 11m
Multiple Airlines
Mon 2/238:22 pm
STL
- CLE
2 stops20h 47m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:29 pm
DTW
- STL
1 stop9h 22m
Multiple Airlines
Mon 2/238:22 pm
STL
- DTW
1 stop16h 08m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$151
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/234:02 pm
CLE
- STL
1 stop8h 57m
Frontier
Thu 2/2610:11 pm
STL
- CLE
1 stop14h 39m
Frontier
Deal found 2/2![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:35 pm
DTW
- STL
1 stop17h 16m
Multiple Airlines
Fri 2/278:22 pm
STL
- DTW
1 stop16h 08m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2710:00 pm
DTW
- STL
1 stop9h 51m
Multiple Airlines
Mon 3/28:22 pm
STL
- DTW
1 stop18h 35m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/32:35 pm
DTW
- STL
1 stop17h 16m
Multiple Airlines
Fri 3/61:09 pm
STL
- DTW
1 stop18h 38m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:30 am
DTW
- MCI
1 stop8h 14m
Frontier
Mon 3/98:38 pm
MCI
- DTW
1 stop13h 21m
Frontier
Deal found 2/1![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Mon 3/92:09 pm
STL
- DTW
1 stop16h 58m
Frontier
Deal found 2/2![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:07 pm
DTW
- STL
1 stop21h 27m
Frontier
Wed 3/1811:32 am
STL
- DTW
1 stop19h 35m
Frontier
Deal found 2/2![Frontier logo]()
$135
One-way flights from Ohio to MissouriSearch for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/711:54 am
DTW
- MCI
1 stop9h 01m
Frontier
Deal found 2/2![Frontier logo]()
$54
This Trip.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:30 am
DTW
- MCI
1 stop8h 14m
Frontier
Deal found 2/1![Frontier logo]()
$58
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:45 pm
CLE
- STL
1 stop11h 06m
Frontier
Deal found 2/2![Frontier logo]()
$60
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:07 pm
CVG
- STL
1 stop18h 44m
Frontier
Deal found 2/2![Frontier logo]()
$60
This Trip.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/228:48 pm
CLE
- STL
1 stop11h 03m
Frontier
Deal found 2/1![Frontier logo]()
$61
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:29 pm
CLE
- STL
1 stop6h 30m
Frontier
Deal found 2/3![Frontier logo]()
$64
This Priceline deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:30 am
DTW
- STL
1 stop8h 23m
Frontier
Deal found 2/2![Frontier logo]()
$64
This Expedia deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/243:20 pm
CVG
- STL
1 stop8h 07m
Frontier
Deal found 1/31![Frontier logo]()
$64
This Priceline deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:30 am
DTW
- MCI
1 stop8h 14m
Frontier
Deal found 1/31![Frontier logo]()
$64
This Trip.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/221:07 pm
CVG
- STL
1 stop18h 44m
Frontier
Deal found 1/31![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:54 am
DTW
- STL
1 stop22h 55m
Frontier
Deal found 2/2![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:02 am
DTW
- STL
1 stop5h 17m
Frontier
Deal found 2/2![Frontier logo]()
$67
Find flight deals from Ohio to Missouri
Keep the following information in mind while searching for Ohio to Missouri flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $131 (Kiwi.com) |
One-way from | $54 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $381 |
Good round-trip deal | $339 or less |
Good one-way deal | $168 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Ohio to Missouri that are best for you.
Fly from
Ohio
Fly to
Missouri
Route
Depart
Return
Price
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 4/4
5:00 am-10:05 am
1 stop6h 05m
Lambert-St Louis
Sat 4/11
5:35 pm-11:00 pm
1 stop4h 25m
$159
ColumbusSt. Louis
CMH - STL
CMHSTL
Columbus
Sun 2/15
11:17 am-6:51 am
1 stop20h 34m
Lambert-St Louis
Mon 2/16
8:22 pm-11:32 pm
2 stops26h 10m
$167
ColumbusSt. Louis
CMH - STL
CMHSTL
Columbus
Mon 2/23
6:53 pm-10:27 pm
1 stop28h 34m
Lambert-St Louis
Fri 2/27
8:22 pm-10:05 am
2 stops12h 43m
$180
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sun 2/15
6:02 pm-6:51 am
1 stop13h 49m
Lambert-St Louis
Wed 2/18
8:17 pm-7:40 pm
2 stops22h 23m
$184
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Sat 4/4
6:30 am-10:03 am
1 stop4h 33m
Lambert-St Louis
Sat 4/11
8:00 am-4:48 pm
1 stop7h 48m
$185
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Wed 4/15
7:40 pm-11:34 pm
1 stop4h 54m
Lambert-St Louis
Sat 4/18
1:03 pm-6:43 pm
1 stop4h 40m
$191
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Wed 4/15
7:40 pm-11:34 pm
1 stop4h 54m
Lambert-St Louis
Tue 4/21
6:48 am-1:35 pm
1 stop5h 47m
$191
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Sat 4/18
6:35 am-11:39 am
1 stop6h 04m
Lambert-St Louis
Wed 4/22
6:00 am-12:48 pm
1 stop5h 48m
$191
ClevelandKansas City
CLE - MCI
CLEMCI
Cleveland Hopkins Intl
Thu 2/19
7:15 am-5:59 pm
2 stops11h 44m
Kansas City
Sun 2/22
10:14 am-11:25 pm
1 stop12h 11m
$199
CincinnatiSt. Louis
CVG - STL
CVGSTL
Cincinnati Cinci./N. Kentucky
Thu 2/19
1:07 pm-6:51 am
1 stop18h 44m
Lambert-St Louis
Fri 2/20
1:59 pm-11:42 pm
1 stop8h 43m
$200
Showing 1-10 of 60 results
Best time to book a flight from Ohio to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Ohio with our price prediction graph.
DTW-MCI
CLE-STL
CVG-STL
DTW-STL
CMH-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Missouri
USOH-USMO
DTW-MCI
CLE-STL
CVG-STL
DTW-STL
What is the cheapest month to book a flight from Ohio to Missouri?
Currently, October is the cheapest month in which you can book a flight from Ohio to Missouri (average of $85). Flying from Ohio to Missouri in March is currently the most expensive (average of $198). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to MO?
Find hourly flight availability from Ohio to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.
It’s optimal to fly from Ohio to Missouri in the evening. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight in the afternoon.
What is the cheapest day to fly from Ohio to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Ohio to Missouri. Price data was last updated on January 31, 2026.
Travelers seeking maximum savings on their Ohio to Missouri flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 3, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Ohio to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Ohio to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Ohio to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from Ohio to Missouri
Discover the top 5 airlines that operate flights from Ohio to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$99 | Average$361 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$159 | Average$230 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$162 | Average$355 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$205 | Average$359 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$222 | Average$374 | FlexibilityNo cancel fee | On-time69% |