$57+ Cheap flights from Ohio to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — STL
Aug 29 — Sep 51
Round-trip
1 adult, Economy
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Find cheap flights from Ohio to Missouri with Cheapflights
1. Tell us where you want to go
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Cheapest flights from Ohio to MissouriExplore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
Explore the most affordable flight options available from Ohio to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:28 pm
CMH
- STL
1 stop19h 42m
Frontier
Mon 10/52:29 pm
STL
- CMH
1 stop27h 26m
Frontier
Deal found 7/29![Frontier logo]()
$115
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:30 pm
CLE
- STL
Nonstop1h 35m
Southwest
Wed 9/167:25 pm
STL
- CLE
Nonstop1h 35m
Southwest
Deal found 7/29![Southwest logo]()
$117
This Frontier deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 am
CLE
- STL
1 stop11h 37m
Frontier
Sat 8/226:45 pm
STL
- CLE
1 stop11h 45m
Frontier
Deal found 7/29![Frontier logo]()
$118
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:20 pm
CLE
- STL
Nonstop1h 35m
Southwest
Tue 9/1510:40 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 7/28![Southwest logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:10 pm
CMH
- STL
1 stop24h 12m
Frontier
Mon 8/246:17 pm
STL
- CMH
1 stop22h 08m
Frontier
Deal found 7/29![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:10 pm
CMH
- MCI
1 stop17h 31m
Frontier
Mon 8/2411:26 am
MCI
- CMH
1 stop28h 59m
Frontier
Deal found 7/26![Frontier logo]()
$126
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:30 pm
CLE
- STL
Nonstop1h 35m
Southwest
Tue 9/1510:15 am
STL
- CLE
2 stops7h 15m
Southwest
Deal found 7/29![Southwest logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 8/316:17 pm
STL
- DTW
1 stop5h 47m
Frontier
Deal found 7/25![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 9/76:17 pm
STL
- DTW
1 stop14h 03m
Frontier
Deal found 7/26![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 9/76:17 pm
STL
- DTW
1 stop14h 03m
Frontier
Deal found 7/27![Frontier logo]()
$135
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:55 am
CLE
- STL
1 stop3h 10m
Southwest
Mon 8/174:15 pm
STL
- CLE
1 stop4h 40m
Southwest
Deal found 7/25![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 8/316:17 pm
STL
- DTW
1 stop5h 47m
Frontier
Deal found 7/26![Frontier logo]()
$137
Best flights from Ohio to MissouriDiscover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
Discover carefully curated flight deals from Ohio to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:20 pm
CLE
- STL
Nonstop1h 35m
Southwest
Wed 9/237:25 pm
STL
- CLE
Nonstop1h 35m
Southwest
Deal found 7/29![Southwest logo]()
$117
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:28 am
CLE
- STL
1 stop5h 38m
Delta
Sat 9/266:40 am
STL
- CLE
1 stop6h 00m
Delta
Deal found 7/28![Delta logo]()
$147
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:34 pm
CVG
- MCI
1 stop16h 48m
Frontier
Mon 10/122:17 pm
MCI
- CVG
1 stop9h 12m
Frontier
Deal found 7/30![Frontier logo]()
$220
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:20 pm
CLE
- STL
Nonstop1h 35m
Southwest
Sat 9/1910:45 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 7/27![Southwest logo]()
$117
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:45 am
PIT
- STL
1 stop4h 17m
United Airlines
Mon 8/318:00 am
STL
- PIT
1 stop4h 15m
United Airlines
Deal found 7/26![United Airlines logo]()
$256
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:25 pm
CLE
- STL
Nonstop1h 35m
Southwest
Sat 9/264:20 pm
STL
- CLE
Nonstop1h 35m
Southwest
Deal found 7/28![Southwest logo]()
$117
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/234:00 pm
CLE
- STL
1 stop5h 35m
Delta
Sat 9/266:40 am
STL
- CLE
1 stop6h 00m
Delta
Deal found 7/28![Delta logo]()
$147
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:28 pm
CAK
- MCI
1 stop5h 55m
American Airlines
Mon 9/213:59 pm
MCI
- CAK
1 stop6h 39m
American Airlines
Deal found 7/26![American Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:20 pm
CLE
- STL
Nonstop1h 35m
Southwest
Thu 9/242:20 pm
STL
- CLE
1 stop3h 20m
Southwest
Deal found 7/29![Southwest logo]()
$127
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:10 am
CLE
- STL
Nonstop1h 35m
Southwest
Mon 10/53:20 pm
STL
- CLE
2 stops6h 35m
Southwest
Deal found 7/28![Southwest logo]()
$132
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:40 am
CLE
- STL
2 stops7h 15m
Southwest
Sat 9/266:50 am
STL
- CLE
2 stops8h 55m
Southwest
Deal found 7/28![Southwest logo]()
$147
This Priceline deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:05 am
CVG
- MCI
1 stop8h 17m
Frontier
Sun 10/252:17 pm
MCI
- CVG
1 stop9h 12m
Frontier
Deal found 7/25![Frontier logo]()
$229
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:15 pm
DTW
- STL
Nonstop1h 45m
Delta
Thu 11/2610:14 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 7/25![Delta logo]()
$227
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:45 am
CAK
- MCI
1 stop6h 33m
United Airlines
Sat 10/105:05 pm
MCI
- CAK
1 stop5h 54m
United Airlines
Deal found 7/27![United Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:58 pm
DTW
- STL
Nonstop1h 37m
Delta
Fri 9/185:59 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 7/28![Delta logo]()
$237
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:09 am
CAK
- MCI
2 stops11h 06m
American Airlines
Mon 9/76:00 am
MCI
- CAK
1 stop5h 11m
American Airlines
Deal found 7/25![American Airlines logo]()
$300
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:10 pm
PIT
- MCI
1 stop4h 37m
United Airlines
Wed 9/167:32 am
MCI
- PIT
1 stop6h 35m
United Airlines
Deal found 7/26![United Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:40 pm
PIT
- STL
1 stop7h 02m
Delta
Sat 9/264:10 pm
STL
- PIT
1 stop5h 45m
Delta
Deal found 7/25![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:35 am
DTW
- STL
Nonstop1h 35m
Southwest
Mon 8/246:50 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 7/27![Southwest logo]()
$197
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:05 pm
CVG
- MCI
1 stop6h 37m
United Airlines
Sun 9/63:14 pm
MCI
- CVG
1 stop4h 29m
United Airlines
Deal found 7/26![United Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:20 pm
PIT
- STL
Nonstop1h 40m
Southwest
Thu 9/310:30 am
STL
- PIT
Nonstop1h 40m
Southwest
Deal found 7/29![Southwest logo]()
$197
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:32 am
CAK
- MCI
1 stop4h 56m
American Airlines
Wed 9/165:00 am
MCI
- CAK
2 stops8h 18m
American Airlines
Deal found 7/26![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:59 pm
CMH
- STL
1 stop4h 28m
Delta
Wed 9/96:40 am
STL
- CMH
1 stop3h 42m
Delta
Deal found 7/29![Delta logo]()
$247
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:55 pm
DTW
- STL
2 stops8h 05m
Southwest
Wed 9/165:55 am
STL
- DTW
1 stop5h 25m
Southwest
Deal found 7/27![Southwest logo]()
$202
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
CMH
- STL
1 stop4h 34m
Delta
Mon 9/144:59 pm
STL
- CMH
1 stop6h 16m
Delta
Deal found 7/29![Delta logo]()
$247
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
CAK
- MCI
1 stop5h 25m
United Airlines
Sat 8/226:00 am
MCI
- CAK
1 stop6h 18m
United Airlines
Deal found 7/25![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:23 pm
CMH
- STL
1 stop6h 35m
Delta
Thu 8/2711:00 am
STL
- CMH
1 stop5h 27m
Delta
Deal found 7/26![Delta logo]()
$247
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:00 am
CLE
- STL
Nonstop1h 45m
Southwest
Mon 11/95:45 am
STL
- CLE
1 stop3h 25m
Southwest
Deal found 7/29![Southwest logo]()
$207
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:40 am
PIT
- STL
Nonstop1h 40m
Southwest
Wed 9/21:50 pm
STL
- PIT
1 stop5h 45m
Southwest
Deal found 7/28![Southwest logo]()
$207
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:20 am
CLE
- MCI
1 stop6h 06m
United Airlines
Sat 10/311:22 am
MCI
- CLE
1 stop4h 38m
United Airlines
Deal found 7/29![United Airlines logo]()
$339
Last-minute flights from Ohio to MissouriDiscover last-minute flight deals from Ohio to Missouri. Data last updated July 30, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to Missouri. Data last updated July 30, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:55 am
CLE
- STL
1 stop3h 10m
Southwest
Mon 8/174:15 pm
STL
- CLE
1 stop4h 40m
Southwest
Deal found 7/25![Southwest logo]()
$137
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:25 pm
CLE
- STL
Nonstop1h 35m
Southwest
Wed 8/1910:40 am
STL
- CLE
Nonstop1h 30m
Southwest
Deal found 7/28![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:40 pm
DTW
- STL
1 stop23h 42m
Frontier
Mon 8/246:17 pm
STL
- DTW
1 stop14h 03m
Frontier
Deal found 7/29![Frontier logo]()
$144
This Frontier deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 am
CLE
- STL
1 stop11h 37m
Frontier
Sat 8/226:45 pm
STL
- CLE
1 stop11h 45m
Frontier
Deal found 7/29![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:10 pm
CMH
- STL
1 stop24h 12m
Frontier
Mon 8/246:17 pm
STL
- CMH
1 stop22h 08m
Frontier
Deal found 7/29![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:10 pm
CMH
- MCI
1 stop17h 31m
Frontier
Mon 8/2411:26 am
MCI
- CMH
1 stop28h 59m
Frontier
Deal found 7/26![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 am
CLE
- STL
1 stop11h 37m
Frontier
Mon 8/246:17 pm
STL
- CLE
1 stop27h 14m
Frontier
Deal found 7/28![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 8/316:17 pm
STL
- DTW
1 stop5h 47m
Frontier
Deal found 7/25![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:45 am
CLE
- STL
1 stop11h 37m
Frontier
Mon 8/316:17 pm
STL
- CLE
1 stop16h 38m
Frontier
Deal found 7/27![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 8/316:17 pm
STL
- DTW
1 stop5h 47m
Frontier
Deal found 7/26![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/308:46 pm
DTW
- STL
1 stop21h 36m
Frontier
Fri 9/46:17 pm
STL
- DTW
1 stop5h 47m
Frontier
Deal found 7/27![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:00 am
DTW
- STL
1 stop12h 22m
Frontier
Mon 9/76:17 pm
STL
- DTW
1 stop14h 03m
Frontier
Deal found 7/26![Frontier logo]()
$134
One-way flights from Ohio to MissouriSearch for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
Search for one-way flight options from Ohio to Missouri. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:10 pm
CMH
- STL
1 stop24h 12m
Frontier
Deal found 7/29![Frontier logo]()
$57
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:28 pm
CMH
- STL
1 stop19h 42m
Frontier
Deal found 7/30![Frontier logo]()
$58
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:20 pm
CLE
- STL
Nonstop1h 35m
Southwest
Deal found 7/25![Southwest logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:10 pm
CMH
- STL
1 stop24h 12m
Frontier
Deal found 7/25![Frontier logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:10 pm
CMH
- MCI
1 stop17h 31m
Frontier
Deal found 7/25![Frontier logo]()
$60
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:00 am
DTW
- STL
1 stop12h 22m
Frontier
Deal found 7/30![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:10 pm
CMH
- MCI
1 stop17h 31m
Frontier
Deal found 7/26![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:11 pm
CMH
- STL
1 stop16h 29m
Frontier
Deal found 7/26![Frontier logo]()
$63
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:23 am
CLE
- STL
1 stop4h 40m
United Airlines
Deal found 7/26![United Airlines logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:26 pm
CVG
- MCI
1 stop23h 15m
Frontier
Deal found 7/25![Frontier logo]()
$65
This Trip.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am
DTW
- STL
1 stop7h 10m
Frontier
Deal found 7/26![Frontier logo]()
$67
This Trip.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:00 am
CLE
- STL
1 stop7h 10m
Frontier
Deal found 7/29![Frontier logo]()
$68
Find flight deals from Ohio to Missouri
Keep the following information in mind while searching for Ohio to Missouri flight deals. Data was last updated July 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $115 (Kiwi.com) |
One-way from | $57 (Kiwi.com) |
Popular in | January |
Cheapest in | September |
Average price | $297 |
Good round-trip deal | $343 or less |
Good one-way deal | $186 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Ohio to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Mon 9/21
7:20 pm-7:55 pm
Nonstop1h 35m
Lambert-St Louis
Wed 9/23
7:25 pm-10:00 pm
Nonstop1h 35m
$117
Quickest round-trip
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Thu 9/17
7:20 pm-7:55 pm
Nonstop1h 35m
Lambert-St Louis
Sat 9/19
10:45 am-1:15 pm
Nonstop1h 30m
$117
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 9/22
7:25 pm-8:00 pm
Nonstop1h 35m
Lambert-St Louis
Sat 9/26
4:20 pm-6:55 pm
Nonstop1h 35m
$117
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Mon 9/21
7:20 pm-7:55 pm
Nonstop1h 35m
Lambert-St Louis
Thu 9/24
2:20 pm-6:40 pm
1 stop3h 20m
$127
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Sat 10/3
7:10 am-7:45 am
Nonstop1h 35m
Lambert-St Louis
Mon 10/5
3:20 pm-10:55 pm
2 stops6h 35m
$132
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Tue 9/22
8:28 am-1:06 pm
1 stop5h 38m
Lambert-St Louis
Sat 9/26
6:40 am-1:40 pm
1 stop6h 00m
$147
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Wed 9/23
4:00 pm-8:35 pm
1 stop5h 35m
Lambert-St Louis
Sat 9/26
6:40 am-1:40 pm
1 stop6h 00m
$147
ClevelandSt. Louis
CLE - STL
CLESTL
Cleveland Hopkins Intl
Wed 9/23
11:40 am-5:55 pm
2 stops7h 15m
Lambert-St Louis
Sat 9/26
6:50 am-4:45 pm
2 stops8h 55m
$147
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 8/22
6:35 am-7:10 am
Nonstop1h 35m
Lambert-St Louis
Mon 8/24
6:50 pm-9:20 pm
Nonstop1h 30m
$197
PittsburghSt. Louis
PIT - STL
PITSTL
Pittsburgh
Thu 8/27
7:20 pm-8:00 pm
Nonstop1h 40m
Lambert-St Louis
Thu 9/3
10:30 am-1:10 pm
Nonstop1h 40m
$197
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Ohio with our price prediction graph.
CMH-STL
CLE-STL
CMH-MCI
DTW-STL
CVG-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to Missouri
USOH-USMO
CMH-STL
CLE-STL
CMH-MCI
DTW-STL
What is the cheapest month to book a flight from Ohio to Missouri?
Currently, September is the cheapest month in which you can book a flight from Ohio to Missouri (average of $317). Flying from Ohio to Missouri in June is currently the most expensive (average of $423). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to MO?
Find hourly flight availability from Ohio to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2026.
It’s optimal to fly from Ohio to Missouri at noon. By choosing this option you can save up to 18% on the cost of your flight, compared to a flight in the afternoon.
How much does it cost to fly round-trip from Ohio to Missouri?
Airfare is below average for this route at the moment.
Ohio to Missouri flights typically cost between $219 and $315 in September.The cheapest round-trip price found within the last 5 days was $117 on Southwest (Sep 9-Sep 16).
How far ahead should I book a flight from Ohio to Missouri?
To ensure you get the cheapest price possible for a flight from Ohio to Missouri, you should look to book at least 50 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Ohio to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Ohio to Missouri. Price data was last updated on July 25, 2026.
Travelers seeking maximum savings on their Ohio to Missouri flight should consider departing on Saturday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 30, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Ohio to Missouri have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Ohio to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Ohio to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to Missouri by cabin class
Find flights from Ohio to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ohio and Missouri flights
Browse other Ohio and Missouri flight options. Last updated on July 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Ohio after your stay in Missouri
Ohio to Missouri flights
Consider these flights traveling from Ohio to Missouri.
Top 5 airlines flying from Ohio to Missouri
Discover the top 5 airlines that operate flights from Ohio to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$91 | Average$186 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$99 | Average$353 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$186 | Average$373 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$187 | Average$396 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$210 | Average$377 | FlexibilityNo cancel fee | On-time69% |