$63+ Cheap flights from North Carolina to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STL
May 1 — May 81
Round-trip
1 adult, Economy
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Find cheap flights from North Carolina to Missouri with Cheapflights
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Cheapest flights from North Carolina to MissouriExplore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.
Explore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/33:42 pm
RDU
- STL
1 stop16h 08m
Frontier
Wed 5/135:27 pm
STL
- RDU
1 stop6h 06m
Frontier
Deal found 3/31![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:49 pm
RDU
- STL
1 stop16h 01m
Frontier
Mon 5/48:23 pm
STL
- RDU
1 stop14h 36m
Frontier
Deal found 3/31![Frontier logo]()
$136
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Mon 4/2711:13 am
MCI
- RDU
1 stop11h 12m
Frontier
Deal found 3/27![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:15 am
RDU
- STL
1 stop11h 39m
Frontier
Sat 5/95:27 pm
STL
- RDU
1 stop6h 02m
Frontier
Deal found 3/30![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Sun 5/311:53 am
MCI
- RDU
1 stop10h 02m
Frontier
Deal found 3/31![Frontier logo]()
$141
This Expedia deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:51 pm
RDU
- STL
1 stop25h 28m
Frontier
Wed 4/224:59 pm
STL
- RDU
1 stop13h 57m
Frontier
Deal found 3/29![Frontier logo]()
$141
This CheapOair deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Fri 4/248:39 am
STL
- CLT
1 stop6h 34m
Frontier
Deal found 3/27![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/294:00 pm
RDU
- STL
1 stop19h 26m
Frontier
Wed 5/65:27 pm
STL
- RDU
1 stop6h 06m
Frontier
Deal found 3/30![Frontier logo]()
$159
This Expedia deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Sun 5/311:53 am
MCI
- RDU
1 stop10h 02m
Frontier
Deal found 3/29![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:54 pm
RDU
- STL
1 stop5h 42m
Frontier
Fri 5/84:19 pm
STL
- RDU
1 stop16h 02m
Frontier
Deal found 3/30![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:54 pm
RDU
- STL
1 stop5h 36m
Frontier
Mon 6/155:33 pm
STL
- RDU
1 stop5h 47m
Frontier
Deal found 3/31![Frontier logo]()
$162
This Orbitz deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:49 pm
RDU
- MCI
1 stop17h 17m
Frontier
Mon 4/2011:13 am
MCI
- RDU
1 stop10h 47m
Frontier
Deal found 3/30![Frontier logo]()
$163
Best flights from North Carolina to MissouriDiscover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2026.
Discover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:06 pm
ORF
- STL
1 stop6h 27m
Multiple Airlines
Thu 5/1412:16 pm
STL
- ORF
2 stops33h 22m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$232
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:35 am
CLT
- STL
1 stop4h 55m
Southwest
Wed 5/61:45 pm
STL
- CLT
1 stop6h 10m
Southwest
Deal found 3/30![Southwest logo]()
$259
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:03 pm
ORF
- SGF
1 stop5h 03m
Delta
Tue 5/126:52 pm
SGF
- ORF
1 stop4h 39m
Delta
Deal found 3/29![Delta logo]()
$320
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:45 am
ORF
- MCI
1 stop5h 40m
United Airlines
Tue 4/283:21 pm
MCI
- ORF
2 stops7h 19m
United Airlines
Deal found 3/29![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:30 pm
MYR
- MCI
1 stop5h 48m
American Airlines
Sat 5/235:27 pm
MCI
- MYR
1 stop5h 23m
American Airlines
Deal found 3/29![American Airlines logo]()
$404
This CheapOair deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:44 pm
ORF
- MCI
1 stop14h 45m
Spirit Airlines
Sun 5/2410:35 am
MCI
- ORF
1 stop7h 14m
Spirit Airlines
Deal found 3/27![Spirit Airlines logo]()
$432
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2612:50 pm
CLT
- STL
Nonstop2h 05m
Southwest
Fri 5/11:45 pm
STL
- CLT
1 stop7h 15m
Southwest
Deal found 3/27![Southwest logo]()
$303
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:59 am
CLT
- MCI
1 stop5h 16m
Delta
Sat 6/206:25 am
MCI
- CLT
1 stop5h 01m
Delta
Deal found 3/31![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:20 am
CLT
- STL
1 stop3h 55m
Southwest
Tue 7/144:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Deal found 3/31![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:35 am
CLT
- MCI
1 stop4h 54m
Delta
Tue 5/265:13 pm
MCI
- CLT
1 stop5h 40m
Delta
Deal found 3/30![Delta logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:20 am
ORF
- MCI
1 stop9h 46m
Multiple Airlines
Sun 4/2611:53 am
MCI
- ORF
1 stop21h 39m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:40 pm
CLT
- STL
Nonstop2h 10m
Southwest
Wed 7/84:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Deal found 3/31![Southwest logo]()
$312
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:12 am
RDU
- SGF
2 stops11h 52m
United Airlines
Sat 5/28:50 am
SGF
- RDU
1 stop6h 05m
United Airlines
Deal found 3/28![United Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:00 am
RDU
- MCI
Nonstop2h 56m
Delta
Sat 5/27:59 pm
MCI
- RDU
Nonstop2h 31m
Delta
Deal found 3/30![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2612:50 pm
CLT
- STL
Nonstop2h 05m
Southwest
Sun 5/311:40 am
STL
- CLT
Nonstop1h 50m
Southwest
Deal found 3/29![Southwest logo]()
$316
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:05 pm
ORF
- MCI
1 stop5h 54m
United Airlines
Mon 4/275:45 pm
MCI
- ORF
1 stop4h 55m
United Airlines
Deal found 3/28![United Airlines logo]()
$410
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:23 am
RDU
- MCI
Nonstop2h 52m
Delta
Wed 5/207:59 pm
MCI
- RDU
Nonstop2h 29m
Delta
Deal found 3/27![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:55 am
RDU
- STL
Nonstop2h 10m
Southwest
Sat 5/235:10 pm
STL
- RDU
Nonstop1h 50m
Southwest
Deal found 3/29![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:00 pm
RDU
- SGF
1 stop8h 04m
United Airlines
Sat 4/256:00 am
SGF
- RDU
2 stops7h 13m
United Airlines
Deal found 3/29![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:04 am
ORF
- SGF
1 stop6h 10m
Delta
Mon 4/276:55 pm
SGF
- ORF
1 stop4h 42m
Delta
Deal found 3/31![Delta logo]()
$344
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:45 pm
RDU
- STL
Nonstop2h 10m
Southwest
Tue 5/56:50 pm
STL
- RDU
Nonstop1h 50m
Southwest
Deal found 3/30![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:05 pm
ORF
- SGF
1 stop5h 59m
United Airlines
Mon 4/273:10 pm
SGF
- ORF
2 stops7h 30m
United Airlines
Deal found 3/31![United Airlines logo]()
$422
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:44 pm
CLT
- STL
1 stop5h 09m
Delta
Sun 8/26:30 am
STL
- CLT
1 stop4h 54m
Delta
Deal found 3/31![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:40 am
CLT
- MCI
2 stops8h 30m
Southwest
Tue 5/55:25 am
MCI
- CLT
2 stops6h 30m
Southwest
Deal found 3/29![Southwest logo]()
$339
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:10 pm
RDU
- MCI
1 stop6h 26m
Delta
Sun 5/247:59 pm
MCI
- RDU
Nonstop2h 29m
Delta
Deal found 3/28![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:12 am
RDU
- SGF
2 stops10h 49m
United Airlines
Sat 4/186:15 am
SGF
- RDU
2 stops10h 03m
United Airlines
Deal found 3/28![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:20 pm
CLT
- STL
1 stop5h 05m
Southwest
Fri 4/241:45 pm
STL
- CLT
2 stops7h 55m
Southwest
Deal found 3/31![Southwest logo]()
$345
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:38 am
RDU
- MCI
1 stop5h 11m
Delta
Mon 4/277:59 pm
MCI
- RDU
Nonstop2h 31m
Delta
Deal found 3/27![Delta logo]()
$352
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
CLT
- MCI
2 stops10h 00m
United Airlines
Mon 6/16:36 pm
MCI
- CLT
1 stop5h 09m
United Airlines
Deal found 3/28![United Airlines logo]()
$440
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:10 pm
RDU
- STL
1 stop6h 00m
Southwest
Wed 7/89:40 am
STL
- RDU
1 stop3h 35m
Southwest
Deal found 3/27![Southwest logo]()
$346
Last-minute flights from North Carolina to MissouriDiscover last-minute flight deals from North Carolina to Missouri. Data last updated April 1, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to Missouri. Data last updated April 1, 2026 and is based on user searches.
This Orbitz deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:49 pm
RDU
- MCI
1 stop17h 17m
Frontier
Mon 4/2011:13 am
MCI
- RDU
1 stop10h 47m
Frontier
Deal found 3/30![Frontier logo]()
$163
This Expedia deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:51 pm
RDU
- STL
1 stop25h 28m
Frontier
Wed 4/224:59 pm
STL
- RDU
1 stop13h 57m
Frontier
Deal found 3/29![Frontier logo]()
$141
This CheapOair deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Fri 4/248:39 am
STL
- CLT
1 stop6h 34m
Frontier
Deal found 3/27![Frontier logo]()
$151
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Mon 4/2711:13 am
MCI
- RDU
1 stop11h 12m
Frontier
Deal found 3/27![Frontier logo]()
$140
This Expedia deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Sun 5/311:53 am
MCI
- RDU
1 stop10h 02m
Frontier
Deal found 3/29![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/294:00 pm
RDU
- STL
1 stop19h 26m
Frontier
Wed 5/65:27 pm
STL
- RDU
1 stop6h 06m
Frontier
Deal found 3/30![Frontier logo]()
$159
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Sun 5/311:53 am
MCI
- RDU
1 stop10h 02m
Frontier
Deal found 3/31![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:49 pm
RDU
- STL
1 stop16h 01m
Frontier
Mon 5/48:23 pm
STL
- RDU
1 stop14h 36m
Frontier
Deal found 3/31![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/33:42 pm
RDU
- STL
1 stop16h 08m
Frontier
Wed 5/135:27 pm
STL
- RDU
1 stop6h 06m
Frontier
Deal found 3/31![Frontier logo]()
$135
This Expedia deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:54 pm
RDU
- STL
1 stop5h 42m
Frontier
Fri 5/84:19 pm
STL
- RDU
1 stop16h 02m
Frontier
Deal found 3/30![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:15 am
RDU
- STL
1 stop11h 39m
Frontier
Sat 5/95:27 pm
STL
- RDU
1 stop6h 02m
Frontier
Deal found 3/30![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2510:36 pm
RDU
- MCI
2 stops43h 53m
Frontier
Wed 7/296:19 pm
MCI
- RDU
1 stop5h 10m
Frontier
Deal found 3/31![Frontier logo]()
$164
One-way flights from North Carolina to MissouriSearch for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated April 1, 2026.
Search for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated April 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:33 pm
RDU
- MCI
1 stop5h 56m
Frontier
Deal found 3/28![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:06 pm
ORF
- MCI
1 stop6h 23m
Frontier
Deal found 3/28![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:15 am
RDU
- MCI
1 stop12h 14m
Frontier
Deal found 3/31![Frontier logo]()
$65
This Trip.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:15 am
RDU
- STL
1 stop12h 18m
Frontier
Deal found 3/31![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:54 pm
RDU
- STL
1 stop5h 36m
Frontier
Deal found 3/30![Frontier logo]()
$69
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 pm
CLT
- STL
1 stop6h 49m
Frontier
Deal found 3/31![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Deal found 3/31![Frontier logo]()
$70
This Priceline deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:51 pm
RDU
- STL
1 stop6h 28m
Frontier
Deal found 3/31![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 pm
ORF
- STL
1 stop6h 19m
Frontier
Deal found 3/31![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:49 pm
RDU
- STL
1 stop16h 01m
Frontier
Deal found 3/31![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:32 am
ORF
- STL
1 stop20h 18m
Frontier
Deal found 3/31![Frontier logo]()
$71
This Expedia deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:54 pm
RDU
- STL
1 stop5h 00m
Frontier
Deal found 3/29![Frontier logo]()
$72
Find flight deals from North Carolina to Missouri
Keep the following information in mind while searching for North Carolina to Missouri flight deals. Data was last updated April 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $135 (Kiwi.com) |
One-way from | $63 (Kiwi.com) |
Popular in | September |
Cheapest in | October |
Average price | $384 |
Good round-trip deal | $295 or less |
Good one-way deal | $194 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from North Carolina to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
NorfolkSt. Louis
ORF - STL
ORFSTL
Norfolk
Tue 5/12
12:06 pm-5:33 pm
1 stop6h 27m
Lambert-St Louis
Thu 5/14
12:16 pm-10:38 pm
2 stops33h 22m
$232
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/29
7:35 am-11:30 am
1 stop4h 55m
Lambert-St Louis
Wed 5/6
1:45 pm-8:55 pm
1 stop6h 10m
$259
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Sun 4/26
12:50 pm-1:55 pm
Nonstop2h 05m
Lambert-St Louis
Fri 5/1
1:45 pm-10:00 pm
1 stop7h 15m
$303
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Tue 7/7
8:20 am-11:15 am
1 stop3h 55m
Lambert-St Louis
Tue 7/14
4:50 pm-7:40 pm
Nonstop1h 50m
$305
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Fri 7/3
4:40 pm-5:50 pm
Nonstop2h 10m
Lambert-St Louis
Wed 7/8
4:50 pm-7:40 pm
Nonstop1h 50m
$312
Quickest round-trip
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Sun 4/26
12:50 pm-1:55 pm
Nonstop2h 05m
Lambert-St Louis
Sun 5/3
11:40 am-2:30 pm
Nonstop1h 50m
$316
NorfolkSpringfield
ORF - SGF
ORFSGF
Norfolk
Fri 5/8
2:03 pm-6:06 pm
1 stop5h 03m
Springfield-Branson
Tue 5/12
6:52 pm-12:31 am
1 stop4h 39m
$320
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Sat 5/23
6:55 am-8:05 am
Nonstop2h 10m
Lambert-St Louis
Sat 5/23
5:10 pm-8:00 pm
Nonstop1h 50m
$327
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Mon 5/4
7:45 pm-8:55 pm
Nonstop2h 10m
Lambert-St Louis
Tue 5/5
6:50 pm-9:40 pm
Nonstop1h 50m
$327
CharlotteKansas City
CLT - MCI
CLTMCI
Charlotte Douglas
Wed 6/17
6:59 am-11:15 am
1 stop5h 16m
Kansas City
Sat 6/20
6:25 am-12:26 pm
1 stop5h 01m
$329
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from North Carolina to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from North Carolina with our price prediction graph.
RDU-STL
RDU-MCI
CLT-STL
ORF-STL
MYR-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Missouri
USNC-USMO
RDU-STL
RDU-MCI
CLT-STL
ORF-STL
What is the cheapest month to book a flight from North Carolina to Missouri?
Currently, May is the cheapest month in which you can book a flight from North Carolina to Missouri (average of $88). Flying from North Carolina to Missouri in March is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to MO?
Find hourly flight availability from North Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2026.
When flying from North Carolina to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 7% versus a flight in the evening.
What is the cheapest day to fly from North Carolina to Missouri?
Use this chart to determine the cheapest time to fly round-trip from North Carolina to Missouri. Price data was last updated on March 28, 2026.
Travelers seeking maximum savings on their North Carolina to Missouri flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from North Carolina to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 1, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from North Carolina to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for North Carolina to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from North Carolina to Missouri by cabin class
Find flights from North Carolina to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
North Carolina and Missouri flights
Browse other North Carolina and Missouri flight options. Last updated on April 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to North Carolina after your stay in Missouri
North Carolina to Missouri flights
Consider these flights traveling from North Carolina to Missouri.
Top 5 airlines flying from North Carolina to Missouri
Discover the top 5 airlines that operate flights from North Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$231 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$147 | Average$327 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$176 | Average$374 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$180 | Average$318 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$196 | Average$372 | FlexibilityNo cancel fee | On-time63% |