$63+ Cheap flights from North Carolina to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STL
Apr 25 — May 21
Round-trip
1 adult, Economy
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Find cheap flights from North Carolina to Missouri with Cheapflights
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Cheapest flights from North Carolina to MissouriExplore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
Explore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:10 am
RDU
- MCI
1 stop5h 24m
Frontier
Mon 5/411:13 am
MCI
- RDU
1 stop10h 47m
Frontier
Deal found 3/25![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:43 pm
RDU
- STL
1 stop12h 11m
Frontier
Sat 4/188:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 3/23![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:51 pm
RDU
- STL
1 stop6h 28m
Frontier
Mon 4/274:59 pm
STL
- RDU
1 stop22h 57m
Frontier
Deal found 3/25![Frontier logo]()
$141
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:10 am
RDU
- STL
1 stop5h 20m
Frontier
Mon 4/274:59 pm
STL
- RDU
1 stop22h 57m
Frontier
Deal found 3/23![Frontier logo]()
$142
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Fri 4/248:39 am
STL
- CLT
1 stop6h 34m
Frontier
Deal found 3/25![Frontier logo]()
$151
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:57 pm
RDU
- STL
1 stop11h 22m
Frontier
Mon 4/274:59 pm
STL
- RDU
1 stop22h 57m
Frontier
Deal found 3/25![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:33 pm
RDU
- MCI
1 stop5h 56m
Frontier
Tue 5/122:34 pm
MCI
- RDU
1 stop19h 57m
Frontier
Deal found 3/25![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:27 am
ORF
- MCI
1 stop24h 07m
Frontier
Sun 5/311:53 am
MCI
- ORF
1 stop22h 43m
Frontier
Deal found 3/25![Frontier logo]()
$158
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:33 pm
CLT
- STL
1 stop16h 18m
Frontier
Sun 4/264:59 pm
STL
- CLT
1 stop15h 28m
Frontier
Deal found 3/21![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Thu 4/2311:53 am
MCI
- RDU
1 stop10h 50m
Frontier
Deal found 3/25![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:02 pm
RDU
- STL
1 stop11h 23m
Frontier
Sat 4/188:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 3/23![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:30 pm
CLT
- STL
1 stop6h 49m
Frontier
Tue 4/284:59 pm
STL
- CLT
1 stop22h 36m
Frontier
Deal found 3/22![Frontier logo]()
$170
Best flights from North Carolina to MissouriDiscover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
Discover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:35 am
CLT
- STL
1 stop4h 55m
Southwest
Wed 5/63:55 pm
STL
- CLT
1 stop4h 00m
Southwest
Deal found 3/25![Southwest logo]()
$209
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:30 am
CLT
- STL
1 stop4h 00m
Delta
Wed 5/131:59 pm
STL
- CLT
1 stop6h 34m
Delta
Deal found 3/21![Delta logo]()
$217
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
MYR
- MCI
1 stop8h 00m
American Airlines
Tue 5/123:11 pm
MCI
- MYR
1 stop6h 51m
American Airlines
Deal found 3/25![American Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:00 am
ORF
- MCI
1 stop7h 26m
United Airlines
Mon 5/116:56 pm
MCI
- ORF
1 stop5h 03m
United Airlines
Deal found 3/24![United Airlines logo]()
$294
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:40 am
CLT
- STL
2 stops7h 20m
Southwest
Wed 6/33:55 pm
STL
- CLT
1 stop4h 00m
Southwest
Deal found 3/25![Southwest logo]()
$214
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:35 am
CLT
- MCI
1 stop7h 15m
Southwest
Tue 4/281:40 pm
MCI
- CLT
2 stops7h 00m
Southwest
Deal found 3/23![Southwest logo]()
$246
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:53 pm
AVL
- STL
1 stop4h 59m
United Airlines
Tue 4/286:30 am
STL
- AVL
1 stop5h 57m
United Airlines
Deal found 3/22![United Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/91:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Tue 6/234:00 pm
STL
- CLT
1 stop4h 10m
Southwest
Deal found 3/24![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:00 am
RDU
- MCI
Nonstop2h 56m
Delta
Sun 4/196:50 am
MCI
- RDU
1 stop6h 58m
Delta
Deal found 3/24![Delta logo]()
$318
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:25 pm
RDU
- SGF
1 stop5h 39m
United Airlines
Sat 4/256:50 pm
SGF
- RDU
1 stop5h 00m
United Airlines
Deal found 3/24![United Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:10 pm
RDU
- STL
1 stop5h 45m
Southwest
Wed 4/291:15 pm
STL
- RDU
1 stop4h 00m
Southwest
Deal found 3/23![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:43 am
AVL
- STL
1 stop5h 51m
Delta
Sun 5/36:00 am
STL
- AVL
1 stop4h 03m
Delta
Deal found 3/21![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:40 am
AVL
- STL
1 stop6h 31m
United Airlines
Sun 6/211:13 pm
STL
- AVL
1 stop6h 57m
United Airlines
Deal found 3/25![United Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:20 pm
CLT
- STL
1 stop5h 05m
Southwest
Sat 5/26:10 am
STL
- CLT
2 stops8h 00m
Southwest
Deal found 3/23![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:45 am
AVL
- STL
1 stop3h 33m
Delta
Fri 8/147:05 pm
STL
- AVL
1 stop3h 38m
Delta
Deal found 3/24![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:40 am
CLT
- MCI
1 stop4h 10m
Southwest
Mon 6/15:15 pm
MCI
- CLT
1 stop4h 25m
Southwest
Deal found 3/25![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:43 am
AVL
- STL
1 stop3h 47m
Delta
Mon 5/44:41 pm
STL
- AVL
1 stop4h 52m
Delta
Deal found 3/21![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:45 am
AVL
- STL
1 stop3h 33m
Delta
Wed 8/1211:51 am
STL
- AVL
1 stop6h 14m
Delta
Deal found 3/24![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:45 am
ORF
- MCI
1 stop7h 18m
United Airlines
Wed 4/296:15 am
MCI
- ORF
1 stop7h 05m
United Airlines
Deal found 3/24![United Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/304:15 pm
CLT
- SGF
Nonstop2h 27m
American Airlines
Thu 8/65:47 pm
SGF
- CLT
1 stop5h 12m
American Airlines
Deal found 3/21![American Airlines logo]()
$495
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:35 am
MYR
- MCI
1 stop5h 15m
Southwest
Tue 5/1212:20 pm
MCI
- MYR
2 stops7h 10m
Southwest
Deal found 3/23![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:43 am
AVL
- STL
1 stop3h 47m
Delta
Tue 5/57:25 am
STL
- AVL
1 stop5h 17m
Delta
Deal found 3/21![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:04 pm
CLT
- SGF
1 stop8h 34m
American Airlines
Sun 4/265:19 am
SGF
- CLT
1 stop8h 03m
American Airlines
Deal found 3/25![American Airlines logo]()
$500
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:26 pm
RDU
- STL
1 stop4h 47m
United Airlines
Sat 5/96:15 am
STL
- RDU
1 stop5h 03m
United Airlines
Deal found 3/24![United Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:20 am
RDU
- SGF
1 stop7h 02m
Delta
Tue 6/96:58 pm
SGF
- RDU
1 stop4h 11m
Delta
Deal found 3/22![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:50 pm
RDU
- STL
1 stop4h 35m
Southwest
Tue 4/286:50 pm
STL
- RDU
Nonstop1h 50m
Southwest
Deal found 3/22![Southwest logo]()
$292
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:41 am
AVL
- STL
1 stop6h 05m
United Airlines
Tue 7/710:20 am
STL
- AVL
2 stops11h 55m
United Airlines
Deal found 3/21![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:20 pm
CLT
- SGF
Nonstop2h 35m
American Airlines
Mon 4/206:24 pm
SGF
- CLT
Nonstop2h 26m
American Airlines
Deal found 3/26![American Airlines logo]()
$516
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:56 pm
RDU
- SGF
1 stop5h 11m
Delta
Mon 5/116:52 pm
SGF
- RDU
1 stop4h 24m
Delta
Deal found 3/22![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:30 pm
CLT
- STL
1 stop3h 45m
Southwest
Sun 5/311:40 am
STL
- CLT
Nonstop1h 50m
Southwest
Deal found 3/24![Southwest logo]()
$299
Last-minute flights from North Carolina to MissouriDiscover last-minute flight deals from North Carolina to Missouri. Data last updated March 26, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to Missouri. Data last updated March 26, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:02 pm
RDU
- STL
1 stop11h 23m
Frontier
Sat 4/188:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 3/23![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:33 pm
CLT
- STL
1 stop16h 18m
Frontier
Sun 4/264:59 pm
STL
- CLT
1 stop15h 28m
Frontier
Deal found 3/21![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:43 pm
RDU
- STL
1 stop12h 11m
Frontier
Sat 4/188:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 3/23![Frontier logo]()
$140
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:30 pm
CLT
- MCI
1 stop20h 36m
Frontier
Mon 5/112:34 pm
MCI
- CLT
1 stop24h 51m
Frontier
Deal found 3/23![Frontier logo]()
$171
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Thu 4/2311:53 am
MCI
- RDU
1 stop10h 50m
Frontier
Deal found 3/25![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Fri 4/248:39 am
STL
- CLT
1 stop6h 34m
Frontier
Deal found 3/25![Frontier logo]()
$151
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:30 pm
CLT
- STL
1 stop6h 49m
Frontier
Tue 4/284:59 pm
STL
- CLT
1 stop22h 36m
Frontier
Deal found 3/22![Frontier logo]()
$170
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Sun 4/264:59 pm
STL
- CLT
1 stop15h 28m
Frontier
Deal found 3/25![Frontier logo]()
$171
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:10 am
RDU
- STL
1 stop5h 20m
Frontier
Mon 4/274:59 pm
STL
- RDU
1 stop22h 57m
Frontier
Deal found 3/23![Frontier logo]()
$142
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:57 pm
RDU
- STL
1 stop11h 22m
Frontier
Mon 4/274:59 pm
STL
- RDU
1 stop22h 57m
Frontier
Deal found 3/25![Frontier logo]()
$151
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:51 pm
RDU
- STL
1 stop6h 28m
Frontier
Mon 4/274:59 pm
STL
- RDU
1 stop22h 57m
Frontier
Deal found 3/25![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:27 am
ORF
- MCI
1 stop24h 07m
Frontier
Sun 5/311:53 am
MCI
- ORF
1 stop22h 43m
Frontier
Deal found 3/25![Frontier logo]()
$158
One-way flights from North Carolina to MissouriSearch for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
Search for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:51 am
RDU
- MCI
1 stop6h 33m
Frontier
Deal found 3/25![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:33 pm
RDU
- MCI
1 stop5h 56m
Frontier
Deal found 3/25![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:06 pm
ORF
- MCI
1 stop6h 23m
Frontier
Deal found 3/25![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:00 pm
RDU
- STL
1 stop15h 50m
Frontier
Deal found 3/21![Frontier logo]()
$69
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:30 pm
CLT
- STL
1 stop6h 49m
Frontier
Deal found 3/25![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Deal found 3/25![Frontier logo]()
$70
This Priceline deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:46 pm
RDU
- STL
1 stop7h 39m
Frontier
Deal found 3/23![Frontier logo]()
$70
This Trip.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
RDU
- STL
1 stop25h 50m
Frontier
Deal found 3/21![Frontier logo]()
$71
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:00 pm
CLT
- STL
1 stop12h 21m
Frontier
Deal found 3/25![Frontier logo]()
$76
This Priceline deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:10 pm
RDU
- STL
1 stop10h 09m
Frontier
Deal found 3/25![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:00 pm
RDU
- MCI
1 stop19h 58m
Frontier
Deal found 3/25![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:15 am
RDU
- STL
1 stop27h 40m
Frontier
Deal found 3/25![Frontier logo]()
$78
Find flight deals from North Carolina to Missouri
Keep the following information in mind while searching for North Carolina to Missouri flight deals. Data was last updated March 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $140 (Frontier) |
One-way from | $63 (Kiwi.com) |
Popular in | September |
Cheapest in | October |
Average price | $411 |
Good round-trip deal | $317 or less |
Good one-way deal | $159 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from North Carolina to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 5/6
7:35 am-11:30 am
1 stop4h 55m
Lambert-St Louis
Wed 5/6
3:55 pm-8:55 pm
1 stop4h 00m
$209
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 6/3
6:40 am-1:00 pm
2 stops7h 20m
Lambert-St Louis
Wed 6/3
3:55 pm-8:55 pm
1 stop4h 00m
$214
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/29
5:30 am-8:30 am
1 stop4h 00m
Lambert-St Louis
Wed 5/13
1:59 pm-9:33 pm
1 stop6h 34m
$217
CharlotteKansas City
CLT - MCI
CLTMCI
Charlotte Douglas
Tue 4/21
7:35 am-1:50 pm
1 stop7h 15m
Kansas City
Tue 4/28
1:40 pm-9:40 pm
2 stops7h 00m
$246
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Tue 6/9
1:25 pm-2:25 pm
Nonstop2h 00m
Lambert-St Louis
Tue 6/23
4:00 pm-9:10 pm
1 stop4h 10m
$252
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Mon 4/27
7:10 pm-11:55 pm
1 stop5h 45m
Lambert-St Louis
Wed 4/29
1:15 pm-6:15 pm
1 stop4h 00m
$253
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Fri 5/1
7:20 pm-11:25 pm
1 stop5h 05m
Lambert-St Louis
Sat 5/2
6:10 am-3:10 pm
2 stops8h 00m
$258
CharlotteKansas City
CLT - MCI
CLTMCI
Charlotte Douglas
Wed 5/27
6:40 am-9:50 am
1 stop4h 10m
Kansas City
Mon 6/1
5:15 pm-10:40 pm
1 stop4h 25m
$258
Myrtle BeachKansas City
MYR - MCI
MYRMCI
Myrtle Beach Intl
Wed 5/6
6:00 am-1:00 pm
1 stop8h 00m
Kansas City
Tue 5/12
3:11 pm-11:02 pm
1 stop6h 51m
$281
Myrtle BeachKansas City
MYR - MCI
MYRMCI
Myrtle Beach Intl
Tue 5/5
7:35 am-11:50 am
1 stop5h 15m
Kansas City
Tue 5/12
12:20 pm-8:30 pm
2 stops7h 10m
$286
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from North Carolina to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from North Carolina with our price prediction graph.
RDU-MCI
ORF-MCI
RDU-STL
CLT-STL
CLT-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Missouri
USNC-USMO
RDU-MCI
ORF-MCI
RDU-STL
CLT-STL
What is the cheapest month to book a flight from North Carolina to Missouri?
Currently, May is the cheapest month in which you can book a flight from North Carolina to Missouri (average of $88). Flying from North Carolina to Missouri in March is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to MO?
Find hourly flight availability from North Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2026.
When flying from North Carolina to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 4% versus a flight in the evening.
What is the cheapest day to fly from North Carolina to Missouri?
Use this chart to determine the cheapest time to fly round-trip from North Carolina to Missouri. Price data was last updated on March 23, 2026.
Travelers seeking maximum savings on their North Carolina to Missouri flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from North Carolina to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 26, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from North Carolina to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for North Carolina to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from North Carolina to Missouri by cabin class
Find flights from North Carolina to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
North Carolina and Missouri flights
Browse other North Carolina and Missouri flight options. Last updated on March 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to North Carolina after your stay in Missouri
North Carolina to Missouri flights
Consider these flights traveling from North Carolina to Missouri.
Top 5 airlines flying from North Carolina to Missouri
Discover the top 5 airlines that operate flights from North Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$231 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$147 | Average$326 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$176 | Average$383 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$180 | Average$318 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$196 | Average$372 | FlexibilityNo cancel fee | On-time63% |