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$64+ Cheap flights from North Carolina to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STL
Feb 4 — Feb 111
Wed 2/4
Wed 2/11
1 adult, Economy
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Cheap flight deals from North Carolina to Missouri

Cheapest flights from North Carolina to Missouri
Explore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 5, 2026.

This Expedia deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/319:10 pmORF - STL
1 stop12h 14mFrontier
Sat 2/75:42 pmSTL - ORF
1 stop26h 10mFrontier
Deal found 1/3$128
This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/296:01 pmCLT - STL
1 stop6h 32mMultiple Airlines
Sun 2/15:42 pmSTL - CLT
1 stop15h 35mMultiple Airlines
Deal found 1/4$140
This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:01 pmCLT - STL
1 stop6h 32mMultiple Airlines
Sun 2/85:42 pmSTL - CLT
1 stop14h 48mMultiple Airlines
Deal found 1/4$143
This Frontier deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/319:59 pmCLT - STL
1 stop11h 25mFrontier
Mon 2/210:16 amSTL - CLT
1 stop7h 39mFrontier
Deal found 1/5$144
This Expedia deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/59:36 pmRDU - STL
1 stop13h 47mFrontier
Sat 2/711:00 amSTL - RDU
1 stop6h 06mFrontier
Deal found 1/4$144
This Kiwi.com deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/296:54 pmCLT - STL
1 stop16h 29mFrontier
Mon 2/210:16 amSTL - CLT
1 stop7h 39mFrontier
Deal found 1/4$154
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/87:29 pmRDU - MCI
1 stop25h 22mFrontier
Fri 2/136:13 pmMCI - RDU
1 stop21h 03mFrontier
Deal found 1/5$155
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:33 pmORF - STL
2 stops29h 00mMultiple Airlines
Mon 2/910:16 amSTL - ORF
1 stop24h 49mMultiple Airlines
Deal found 1/5$159
This Frontier deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/226:54 pmCLT - STL
1 stop5h 39mFrontier
Mon 1/2610:16 amSTL - CLT
1 stop7h 39mFrontier
Deal found 1/4$160
This Frontier deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/26:10 amRDU - MCI
1 stop6h 40mFrontier
Mon 2/912:45 pmMCI - RDU
1 stop10h 26mFrontier
Deal found 1/5$160
This Frontier deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/202:54 pmRDU - STL
1 stop9h 39mFrontier
Sat 1/2411:00 amSTL - RDU
1 stop6h 06mFrontier
Deal found 1/5$160
This Kiwi.com deal was found by Cheapflights users on 1/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/239:59 pmCLT - STL
1 stop14h 12mFrontier
Sun 1/255:42 pmSTL - CLT
1 stop14h 48mFrontier
Deal found 1/3$162

Find flight deals from North Carolina to Missouri

Keep the following information in mind while searching for North Carolina to Missouri flight deals. Data was last updated January 5, 2026.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$128
(Expedia)

One-way from

$64
(Frontier)

Popular in

September

Cheapest in

October

Average price

$374

Good round-trip deal

$199 or less

Good one-way deal

$148 or less
Provider with most accurate pricing for Raleigh-Durham-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Lambert-St Louis flights.
Search Deals
From North Carolina to Missouri
Search Deals
One-way flight from North Carolina to Missouri
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from North Carolina to Missouri.
Search Deals
Price to beat on a one-way flight from North Carolina to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 5, 2026.
Use the filters below to find and compare flights from North Carolina to Missouri that are best for you.

Fly from

North Carolina

Fly to

Missouri

Route

Depart

Return

Price

AshevilleSt. Louis

AVL - STL

AVLSTL

Asheville Regional

Thu 2/5

4:16 pm-10:23 am

1 stop19h 07m

Lambert-St Louis

Mon 2/9

5:42 pm-5:03 pm

1 stop22h 21m

$183

AshevilleSt. Louis

AVL - STL

AVLSTL

Asheville Regional

Fri 2/6

9:10 am-11:33 pm

1 stop15h 23m

Lambert-St Louis

Sun 2/8

5:42 pm-9:52 pm

1 stop27h 10m

$185

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 2/3

8:25 am-9:35 am

Nonstop2h 10m

Lambert-St Louis

Tue 2/10

2:30 pm-5:15 pm

Nonstop1h 45m

$186

AshevilleSt. Louis

AVL - STL

AVLSTL

Asheville Regional

Fri 1/30

9:10 am-11:33 pm

1 stop15h 23m

Lambert-St Louis

Mon 2/2

10:16 am-9:52 pm

1 stop10h 36m

$186

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Thu 2/19

7:09 am-9:16 am

Nonstop3h 07m

Kansas City

Sun 3/15

7:59 pm-11:24 pm

Nonstop2h 25m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Tue 3/31

8:00 am-1:15 pm

2 stops6h 15m

Kansas City

Sun 4/5

6:15 am-12:55 pm

1 stop5h 40m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Wed 3/25

7:00 am-8:55 am

Nonstop2h 55m

Kansas City

Sun 3/29

7:59 pm-11:24 pm

Nonstop2h 25m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Mon 2/2

7:05 am-9:14 am

Nonstop3h 09m

Kansas City

Mon 2/9

7:59 pm-11:24 pm

Nonstop2h 25m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Tue 2/24

7:09 am-9:16 am

Nonstop3h 07m

Kansas City

Mon 3/2

7:59 pm-11:22 pm

Nonstop2h 23m

$199

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Fri 2/27

7:09 am-9:16 am

Nonstop3h 07m

Kansas City

Mon 3/2

7:59 pm-11:22 pm

Nonstop2h 23m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/3

Showing 1-10 of 60 results
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Best time to book a flight from North Carolina to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Missouri

What is the cheapest month to book a flight from North Carolina to Missouri?

Currently, May is the cheapest month in which you can book a flight from North Carolina to Missouri (average of $88). Flying from North Carolina to Missouri in April is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to MO?

Find hourly flight availability from North Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 5, 2026.

When flying from North Carolina to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 4% versus a flight in the evening.

What is the cheapest day to fly from North Carolina to Missouri?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to Missouri. Price data was last updated on January 3, 2026.

Travelers seeking maximum savings on their North Carolina to Missouri flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 5, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from North Carolina to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,018 reviews
Southwest
8.0
Very good
4,248 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,132 reviews
Southwest
8.0
Very good
4,248 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,084 reviews
Southwest
8.0
Very good
4,248 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.7
Fair
3,063 reviews
Southwest
8.0
Very good
4,248 reviews

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this North Carolina to Missouri flight route?

    This flight path from North Carolina to Missouri was viewed by 28 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from North Carolina to Missouri?

    Southwest, Delta, and Frontier can get you from North Carolina to Missouri in just under 2h 10m. Your travel time can differ by up to 16h 13m. Airlines will cover a distance of 574 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from North Carolina to Missouri that include hotel bookings?

    Yes. In addition to deals on North Carolina to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Missouri.

  • Can I find deals for business class flights from North Carolina to Missouri?

    Yes. Cheapflights offers flight deals from North Carolina to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Missouri?

    Currently, May is the cheapest month in which you can book a flight from North Carolina to Missouri (average of $88). Flying from North Carolina to Missouri in April is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for North Carolina to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from North Carolina to Missouri

Discover the top 6 airlines that operate flights from North Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$141Average$250FlexibilityNo cancel feeOn-time62%
DeltaCheapest$149Average$325FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$176Average$394FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$196Average$375FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$196Average$364FlexibilityNo cancel feeOn-time69%
Spirit AirlinesCheapest$218Average$356FlexibilityNo cancel feeOn-time65%

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