$60+ Cheap flights from North Carolina to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STL
May 7 — May 141
Round-trip
1 adult, Economy
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Find cheap flights from North Carolina to Missouri with Cheapflights
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Cheapest flights from North Carolina to MissouriExplore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
Explore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:06 pm
ORF
- MCI
1 stop6h 23m
Frontier
Wed 6/106:19 pm
MCI
- ORF
1 stop16h 07m
Frontier
Deal found 4/6![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:10 am
RDU
- STL
1 stop5h 16m
Frontier
Mon 5/48:23 pm
STL
- RDU
1 stop14h 41m
Frontier
Deal found 4/4![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/33:42 pm
RDU
- STL
1 stop16h 08m
Frontier
Wed 5/65:27 pm
STL
- RDU
1 stop6h 06m
Frontier
Deal found 4/2![Frontier logo]()
$135
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:57 pm
RDU
- STL
1 stop4h 57m
Frontier
Sat 5/95:27 pm
STL
- RDU
1 stop6h 02m
Frontier
Deal found 4/6![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:20 pm
RDU
- MCI
1 stop19h 30m
Multiple Airlines
Mon 6/86:24 pm
MCI
- RDU
1 stop16h 35m
Multiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:20 pm
RDU
- MCI
1 stop19h 30m
Multiple Airlines
Wed 6/106:19 pm
MCI
- RDU
1 stop16h 40m
Multiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:15 am
RDU
- STL
1 stop12h 18m
Frontier
Sat 6/65:27 pm
STL
- RDU
1 stop5h 59m
Frontier
Deal found 4/3![Frontier logo]()
$147
This CheapOair deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:48 pm
RDU
- STL
1 stop27h 31m
Frontier
Mon 4/274:59 pm
STL
- RDU
1 stop22h 57m
Frontier
Deal found 4/3![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:06 pm
ORF
- MCI
1 stop6h 23m
Frontier
Sat 5/96:24 pm
MCI
- ORF
1 stop15h 47m
Frontier
Deal found 4/2![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:31 pm
RDU
- MCI
1 stop16h 27m
Frontier
Sat 5/96:24 pm
MCI
- RDU
1 stop16h 38m
Frontier
Deal found 4/2![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:21 pm
ORF
- MCI
1 stop6h 03m
Frontier
Mon 8/36:19 pm
MCI
- ORF
1 stop16h 07m
Frontier
Deal found 4/5![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:32 pm
RDU
- STL
2 stops36h 23m
Frontier
Mon 5/115:27 pm
STL
- RDU
1 stop5h 57m
Frontier
Deal found 4/6![Frontier logo]()
$159
Best flights from North Carolina to MissouriDiscover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
Discover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:59 am
CLT
- STL
1 stop3h 45m
Delta
Sat 5/166:45 am
STL
- CLT
1 stop4h 29m
Delta
Deal found 4/5![Delta logo]()
$217
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:40 am
CLT
- STL
2 stops9h 10m
Southwest
Mon 6/83:35 pm
STL
- CLT
2 stops6h 40m
Southwest
Deal found 4/5![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:58 am
RDU
- SGF
1 stop4h 54m
American Airlines
Tue 6/26:12 pm
SGF
- RDU
1 stop4h 55m
American Airlines
Deal found 4/6![American Airlines logo]()
$276
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:32 am
RDU
- SGF
2 stops9h 11m
United Airlines
Tue 6/26:41 pm
SGF
- RDU
1 stop5h 09m
United Airlines
Deal found 4/6![United Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/129:56 pm
ORF
- MCI
2 stops20h 28m
Frontier
Fri 7/246:19 pm
MCI
- ORF
1 stop16h 01m
Frontier
Deal found 4/3![Frontier logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:57 pm
CLT
- SGF
1 stop22h 36m
Multiple Airlines
Thu 6/118:10 pm
SGF
- CLT
2 stops22h 52m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:55 am
CLT
- STL
1 stop6h 37m
Delta
Wed 5/137:15 am
STL
- CLT
1 stop5h 12m
Delta
Deal found 4/4![Delta logo]()
$217
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:10 am
CLT
- STL
1 stop6h 35m
Southwest
Sun 5/1011:40 am
STL
- CLT
Nonstop1h 50m
Southwest
Deal found 4/5![Southwest logo]()
$260
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:35 am
CLT
- STL
1 stop3h 35m
Delta
Tue 5/1910:19 am
STL
- CLT
1 stop4h 31m
Delta
Deal found 4/2![Delta logo]()
$254
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:45 pm
RDU
- STL
Nonstop2h 10m
Southwest
Mon 5/42:10 pm
STL
- RDU
1 stop4h 30m
Southwest
Deal found 4/4![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/288:05 am
CLT
- STL
1 stop5h 06m
United Airlines
Sat 7/41:13 pm
STL
- CLT
1 stop7h 16m
United Airlines
Deal found 4/2![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:15 pm
RDU
- SGF
1 stop7h 04m
Delta
Wed 6/36:49 pm
SGF
- RDU
1 stop4h 27m
Delta
Deal found 4/6![Delta logo]()
$296
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:50 pm
TYS
- MCI
1 stop5h 50m
Southwest
Sat 5/26:45 am
MCI
- TYS
2 stops10h 45m
Southwest
Deal found 4/2![Southwest logo]()
$308
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:15 pm
RDU
- SGF
1 stop5h 09m
United Airlines
Sat 4/256:15 am
SGF
- RDU
1 stop8h 28m
United Airlines
Deal found 4/5![United Airlines logo]()
$339
This KAYAK deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:04 am
ORF
- MCI
1 stop7h 21m
American Airlines
Sat 8/11:23 pm
MCI
- ORF
1 stop6h 58m
American Airlines
Deal found 4/2![American Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:44 am
RDU
- STL
1 stop4h 21m
Delta
Sun 5/36:00 am
STL
- RDU
1 stop6h 21m
Delta
Deal found 4/4![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:40 am
TYS
- MCI
2 stops6h 35m
Southwest
Sat 5/912:35 pm
MCI
- TYS
1 stop6h 00m
Southwest
Deal found 4/4![Southwest logo]()
$316
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
CLT
- STL
2 stops7h 11m
United Airlines
Sat 6/271:13 pm
STL
- CLT
1 stop7h 16m
United Airlines
Deal found 4/3![United Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:40 am
ORF
- SGF
1 stop25h 21m
Multiple Airlines
Sat 7/186:19 pm
SGF
- ORF
1 stop16h 55m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:35 am
CLT
- STL
1 stop5h 09m
Delta
Sun 5/106:00 am
STL
- CLT
1 stop4h 05m
Delta
Deal found 4/4![Delta logo]()
$313
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:45 pm
TYS
- MCI
1 stop5h 50m
Southwest
Mon 6/81:45 pm
MCI
- TYS
2 stops6h 25m
Southwest
Deal found 4/1![Southwest logo]()
$316
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:12 pm
MYR
- MCI
1 stop5h 55m
American Airlines
Thu 5/285:33 am
MCI
- MYR
2 stops9h 25m
American Airlines
Deal found 4/3![American Airlines logo]()
$427
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:25 pm
RDU
- STL
1 stop4h 48m
United Airlines
Tue 4/216:30 am
STL
- RDU
2 stops6h 36m
United Airlines
Deal found 4/3![United Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:55 pm
TYS
- MCI
2 stops5h 30m
Southwest
Wed 7/810:15 am
MCI
- TYS
2 stops9h 05m
Southwest
Deal found 4/6![Southwest logo]()
$321
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:59 am
CLT
- STL
1 stop3h 47m
Delta
Sat 7/48:00 am
STL
- CLT
1 stop4h 35m
Delta
Deal found 4/6![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:32 am
RDU
- SGF
2 stops8h 34m
United Airlines
Wed 6/36:00 am
SGF
- RDU
1 stop5h 33m
United Airlines
Deal found 4/2![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:30 pm
MYR
- MCI
1 stop5h 48m
American Airlines
Sat 5/166:00 am
MCI
- MYR
2 stops8h 39m
American Airlines
Deal found 4/6![American Airlines logo]()
$436
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:50 pm
TYS
- MCI
1 stop5h 50m
Southwest
Sat 6/61:20 pm
MCI
- TYS
2 stops5h 15m
Southwest
Deal found 4/4![Southwest logo]()
$322
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/229:35 am
CLT
- STL
1 stop4h 42m
Delta
Sun 9/273:42 pm
STL
- CLT
1 stop4h 56m
Delta
Deal found 4/4![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:05 pm
ORF
- SGF
1 stop5h 59m
United Airlines
Sat 4/256:15 am
SGF
- ORF
2 stops9h 28m
United Airlines
Deal found 4/6![United Airlines logo]()
$364
Last-minute flights from North Carolina to MissouriDiscover last-minute flight deals from North Carolina to Missouri. Data last updated April 7, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to Missouri. Data last updated April 7, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Fri 4/248:39 am
STL
- CLT
1 stop6h 34m
Frontier
Deal found 4/3![Frontier logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:40 pm
RDU
- STL
2 stops18h 10m
Frontier
Wed 4/228:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 4/3![Frontier logo]()
$167
This CheapOair deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Sun 4/264:59 pm
STL
- CLT
1 stop15h 28m
Frontier
Deal found 4/3![Frontier logo]()
$171
This CheapOair deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:48 pm
RDU
- STL
1 stop27h 31m
Frontier
Mon 4/274:59 pm
STL
- RDU
1 stop22h 57m
Frontier
Deal found 4/3![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:10 am
RDU
- STL
1 stop5h 16m
Frontier
Mon 5/48:23 pm
STL
- RDU
1 stop14h 41m
Frontier
Deal found 4/4![Frontier logo]()
$133
This Expedia deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/19:49 pm
RDU
- MCI
1 stop17h 17m
Frontier
Mon 5/42:15 pm
MCI
- RDU
1 stop21h 13m
Frontier
Deal found 4/2![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:31 pm
RDU
- MCI
1 stop16h 27m
Frontier
Sat 5/96:24 pm
MCI
- RDU
1 stop16h 38m
Frontier
Deal found 4/2![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/33:42 pm
RDU
- STL
1 stop16h 08m
Frontier
Wed 5/65:27 pm
STL
- RDU
1 stop6h 06m
Frontier
Deal found 4/2![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:32 pm
RDU
- STL
2 stops36h 23m
Frontier
Mon 5/115:27 pm
STL
- RDU
1 stop5h 57m
Frontier
Deal found 4/6![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:06 pm
ORF
- MCI
1 stop6h 23m
Frontier
Sat 5/96:24 pm
MCI
- ORF
1 stop15h 47m
Frontier
Deal found 4/2![Frontier logo]()
$156
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:57 pm
RDU
- STL
1 stop4h 57m
Frontier
Sat 5/95:27 pm
STL
- RDU
1 stop6h 02m
Frontier
Deal found 4/6![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:06 pm
ORF
- MCI
1 stop6h 23m
Frontier
Wed 6/106:19 pm
MCI
- ORF
1 stop16h 07m
Frontier
Deal found 4/6![Frontier logo]()
$124
One-way flights from North Carolina to MissouriSearch for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
Search for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
This Trip.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:15 am
RDU
- MCI
1 stop12h 14m
Frontier
Deal found 4/2![Frontier logo]()
$60
This Trip.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:15 am
RDU
- STL
1 stop12h 18m
Frontier
Deal found 4/3![Frontier logo]()
$60
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:00 pm
ORF
- MCI
1 stop6h 24m
Frontier
Deal found 4/5![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:00 pm
RDU
- STL
1 stop15h 50m
Frontier
Deal found 4/5![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
RDU
- MCI
1 stop12h 14m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:59 pm
RDU
- STL
1 stop20h 56m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Trip.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:15 am
RDU
- STL
1 stop11h 39m
Frontier
Deal found 4/6![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2312:54 pm
RDU
- STL
1 stop5h 36m
Frontier
Deal found 4/2![Frontier logo]()
$69
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:58 pm
CLT
- STL
1 stop5h 23m
Frontier
Deal found 4/6![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Deal found 4/6![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:21 pm
ORF
- MCI
1 stop6h 03m
Frontier
Deal found 4/3![Frontier logo]()
$70
This WAYA deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:10 am
RDU
- STL
1 stop5h 16m
Frontier
Deal found 4/5![Frontier logo]()
$70
Find flight deals from North Carolina to Missouri
Keep the following information in mind while searching for North Carolina to Missouri flight deals. Data was last updated April 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $124 (Kiwi.com) |
One-way from | $60 (Trip.com) |
Popular in | March |
Cheapest in | October |
Average price | $384 |
Good round-trip deal | $303 or less |
Good one-way deal | $188 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from North Carolina to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 5/13
6:59 am-9:44 am
1 stop3h 45m
Lambert-St Louis
Sat 5/16
6:45 am-12:14 pm
1 stop4h 29m
$217
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/29
9:55 am-3:32 pm
1 stop6h 37m
Lambert-St Louis
Wed 5/13
7:15 am-1:27 pm
1 stop5h 12m
$217
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Tue 6/2
6:40 am-2:50 pm
2 stops9h 10m
Lambert-St Louis
Mon 6/8
3:35 pm-11:15 pm
2 stops6h 40m
$248
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Fri 5/15
5:35 am-8:10 am
1 stop3h 35m
Lambert-St Louis
Tue 5/19
10:19 am-3:50 pm
1 stop4h 31m
$254
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Sat 5/9
6:10 am-11:45 am
1 stop6h 35m
Lambert-St Louis
Sun 5/10
11:40 am-2:30 pm
Nonstop1h 50m
$260
RaleighSpringfield
RDU - SGF
RDUSGF
Raleigh-Durham
Wed 5/27
8:58 am-12:52 pm
1 stop4h 54m
Springfield-Branson
Tue 6/2
6:12 pm-12:07 am
1 stop4h 55m
$276
Quickest round-trip
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Thu 4/30
7:45 pm-8:55 pm
Nonstop2h 10m
Lambert-St Louis
Mon 5/4
2:10 pm-7:40 pm
1 stop4h 30m
$287
RaleighSpringfield
RDU - SGF
RDUSGF
Raleigh-Durham
Wed 5/27
10:32 am-6:43 pm
2 stops9h 11m
Springfield-Branson
Tue 6/2
6:41 pm-12:50 am
1 stop5h 09m
$296
RaleighSpringfield
RDU - SGF
RDUSGF
Raleigh-Durham
Thu 5/28
4:15 pm-10:19 pm
1 stop7h 04m
Springfield-Branson
Wed 6/3
6:49 pm-12:16 am
1 stop4h 27m
$296
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Thu 4/30
9:44 am-1:05 pm
1 stop4h 21m
Lambert-St Louis
Sun 5/3
6:00 am-1:21 pm
1 stop6h 21m
$297
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from North Carolina to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from North Carolina with our price prediction graph.
ORF-MCI
RDU-STL
RDU-MCI
CLT-STL
RDU-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Missouri
USNC-USMO
ORF-MCI
RDU-STL
RDU-MCI
CLT-STL
What is the cheapest month to book a flight from North Carolina to Missouri?
Currently, May is the cheapest month in which you can book a flight from North Carolina to Missouri (average of $88). Flying from North Carolina to Missouri in February is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to MO?
Find hourly flight availability from North Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 7, 2026.
When flying from North Carolina to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 7% versus a flight in the evening.
What is the cheapest day to fly from North Carolina to Missouri?
Use this chart to determine the cheapest time to fly round-trip from North Carolina to Missouri. Price data was last updated on April 4, 2026.
Travelers seeking maximum savings on their North Carolina to Missouri flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from North Carolina to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 7, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from North Carolina to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for North Carolina to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from North Carolina to Missouri by cabin class
Find flights from North Carolina to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
North Carolina and Missouri flights
Browse other North Carolina and Missouri flight options. Last updated on April 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to North Carolina after your stay in Missouri
North Carolina to Missouri flights
Consider these flights traveling from North Carolina to Missouri.
Top 5 airlines flying from North Carolina to Missouri
Discover the top 5 airlines that operate flights from North Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$234 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$147 | Average$329 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$180 | Average$320 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$192 | Average$377 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$372 | FlexibilityNo cancel fee | On-time63% |