$64+ Cheap flights from North Carolina to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STL
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from North Carolina to Missouri with Cheapflights
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Cheapest flights from North Carolina to MissouriExplore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
RDU
- STL
1 stop5h 31m
Frontier
Tue 3/3111:27 am
STL
- RDU
1 stop11h 44m
Frontier
Deal found 3/5![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
RDU
- STL
1 stop12h 34m
Frontier
Tue 4/711:21 am
STL
- RDU
1 stop26h 41m
Frontier
Deal found 3/10![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:07 pm
RDU
- STL
1 stop15h 43m
Frontier
Mon 5/188:13 pm
STL
- RDU
1 stop17h 51m
Frontier
Deal found 3/6![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:10 am
RDU
- STL
1 stop5h 16m
Frontier
Mon 5/48:23 pm
STL
- RDU
1 stop17h 41m
Frontier
Deal found 3/9![Frontier logo]()
$159
This Priceline deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:33 pm
CLT
- STL
1 stop7h 52m
Frontier
Mon 4/134:59 pm
STL
- CLT
1 stop6h 37m
Frontier
Deal found 3/9![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Sun 4/1911:53 am
MCI
- RDU
1 stop10h 47m
Frontier
Deal found 3/5![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:51 pm
RDU
- STL
1 stop6h 28m
Frontier
Sun 4/2611:44 am
STL
- RDU
1 stop10h 11m
Frontier
Deal found 3/5![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/263:42 pm
RDU
- STL
1 stop16h 08m
Frontier
Thu 4/3011:21 am
STL
- RDU
1 stop10h 59m
Frontier
Deal found 3/9![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:27 am
ORF
- STL
1 stop20h 23m
Frontier
Thu 4/3011:21 am
STL
- ORF
1 stop21h 56m
Frontier
Deal found 3/10![Frontier logo]()
$162
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:30 pm
CLT
- STL
1 stop26h 02m
Frontier
Sun 4/264:59 pm
STL
- CLT
1 stop15h 28m
Frontier
Deal found 3/7![Frontier logo]()
$170
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Fri 4/248:06 pm
STL
- CLT
1 stop19h 50m
Frontier
Deal found 3/5![Frontier logo]()
$171
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:48 pm
RDU
- STL
1 stop28h 31m
Frontier
Sat 5/94:55 pm
STL
- RDU
1 stop14h 01m
Frontier
Deal found 3/5![Frontier logo]()
$171
Best flights from North Carolina to MissouriDiscover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:00 am
CLT
- STL
2 stops8h 15m
Southwest
Wed 4/1512:40 pm
STL
- CLT
2 stops8h 00m
Southwest
Deal found 3/10![Southwest logo]()
$227
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:36 am
CLT
- STL
1 stop4h 29m
Delta
Mon 5/44:41 pm
STL
- CLT
1 stop3h 46m
Delta
Deal found 3/7![Delta logo]()
$234
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:15 am
RDU
- SGF
2 stops10h 09m
United Airlines
Sat 4/256:50 pm
SGF
- RDU
1 stop5h 00m
United Airlines
Deal found 3/9![United Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:07 am
ORF
- STL
1 stop20h 43m
Multiple Airlines
Sun 4/194:59 pm
STL
- ORF
1 stop23h 05m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$339
This CheapOair deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:41 pm
ORF
- MCI
1 stop15h 48m
Spirit Airlines
Wed 4/112:24 pm
MCI
- ORF
1 stop6h 22m
Spirit Airlines
Deal found 3/9![Spirit Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:03 am
RDU
- SGF
1 stop7h 48m
American Airlines
Tue 6/96:12 pm
SGF
- RDU
1 stop4h 55m
American Airlines
Deal found 3/5![American Airlines logo]()
$406
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:00 am
CLT
- STL
2 stops8h 15m
Southwest
Mon 4/131:45 pm
STL
- CLT
2 stops7h 55m
Southwest
Deal found 3/9![Southwest logo]()
$238
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:36 am
CLT
- STL
1 stop4h 29m
Delta
Thu 5/76:00 am
STL
- CLT
1 stop4h 06m
Delta
Deal found 3/8![Delta logo]()
$253
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:30 pm
CLT
- STL
1 stop3h 45m
Southwest
Sat 5/25:40 am
STL
- CLT
2 stops8h 30m
Southwest
Deal found 3/6![Southwest logo]()
$244
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:55 pm
TYS
- STL
1 stop4h 21m
United Airlines
Mon 7/65:41 pm
STL
- TYS
1 stop5h 49m
United Airlines
Deal found 3/6![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
CLT
- STL
1 stop4h 42m
Delta
Thu 4/236:50 pm
STL
- CLT
1 stop4h 03m
Delta
Deal found 3/5![Delta logo]()
$258
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:36 am
CLT
- STL
1 stop4h 29m
Delta
Sun 5/36:50 pm
STL
- CLT
1 stop4h 03m
Delta
Deal found 3/7![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:25 pm
TYS
- STL
1 stop5h 40m
Southwest
Thu 4/910:50 am
STL
- TYS
2 stops8h 30m
Southwest
Deal found 3/5![Southwest logo]()
$262
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:07 pm
RDU
- STL
1 stop5h 09m
United Airlines
Sun 6/75:41 pm
STL
- RDU
1 stop6h 09m
United Airlines
Deal found 3/9![United Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:40 am
CLT
- STL
2 stops7h 20m
Southwest
Thu 4/304:00 pm
STL
- CLT
1 stop4h 40m
Southwest
Deal found 3/5![Southwest logo]()
$263
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:15 am
RDU
- STL
1 stop6h 56m
United Airlines
Thu 6/256:00 am
STL
- RDU
1 stop5h 33m
United Airlines
Deal found 3/8![United Airlines logo]()
$297
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:40 am
TYS
- MCI
1 stop4h 45m
Delta
Sat 4/115:25 pm
MCI
- TYS
1 stop5h 32m
Delta
Deal found 3/5![Delta logo]()
$287
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:05 am
CLT
- MCI
1 stop6h 00m
Southwest
Wed 4/153:30 pm
MCI
- CLT
1 stop4h 25m
Southwest
Deal found 3/9![Southwest logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:07 pm
RDU
- SGF
2 stops18h 27m
Multiple Airlines
Mon 5/118:23 pm
SGF
- RDU
1 stop19h 33m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:01 pm
TYS
- MCI
1 stop6h 30m
United Airlines
Wed 5/69:45 am
MCI
- TYS
1 stop6h 23m
United Airlines
Deal found 3/9![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:15 am
RDU
- SGF
1 stop5h 52m
Delta
Fri 4/246:55 pm
SGF
- RDU
1 stop4h 23m
Delta
Deal found 3/6![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:55 pm
TYS
- STL
1 stop5h 25m
Southwest
Sat 5/3010:35 am
STL
- TYS
2 stops6h 55m
Southwest
Deal found 3/7![Southwest logo]()
$273
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:20 am
TYS
- MCI
1 stop7h 00m
United Airlines
Mon 5/254:56 pm
MCI
- TYS
1 stop6h 34m
United Airlines
Deal found 3/6![United Airlines logo]()
$312
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:45 am
RDU
- STL
1 stop4h 45m
Delta
Thu 6/185:30 pm
STL
- RDU
1 stop5h 56m
Delta
Deal found 3/6![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:35 am
TYS
- STL
2 stops9h 05m
Southwest
Thu 4/210:25 am
STL
- TYS
1 stop7h 20m
Southwest
Deal found 3/5![Southwest logo]()
$280
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:25 pm
RDU
- MCI
1 stop5h 34m
United Airlines
Tue 4/213:21 pm
MCI
- RDU
1 stop5h 02m
United Airlines
Deal found 3/5![United Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:30 am
TYS
- STL
1 stop6h 15m
Delta
Mon 7/67:05 pm
STL
- TYS
1 stop3h 41m
Delta
Deal found 3/5![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:20 am
CLT
- STL
2 stops8h 05m
Southwest
Mon 4/131:45 pm
STL
- CLT
2 stops7h 55m
Southwest
Deal found 3/6![Southwest logo]()
$281
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:00 pm
RDU
- SGF
1 stop8h 04m
United Airlines
Sat 4/256:00 am
SGF
- RDU
2 stops11h 08m
United Airlines
Deal found 3/8![United Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
CLT
- MCI
1 stop4h 38m
Delta
Sat 6/201:13 pm
MCI
- CLT
1 stop4h 01m
Delta
Deal found 3/6![Delta logo]()
$309
Last-minute flights from North Carolina to MissouriDiscover last-minute flight deals from North Carolina to Missouri. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to Missouri. Data last updated March 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
RDU
- STL
1 stop5h 31m
Frontier
Tue 3/3111:27 am
STL
- RDU
1 stop11h 44m
Frontier
Deal found 3/5![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:57 pm
RDU
- STL
1 stop26h 37m
Frontier
Wed 4/158:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 3/9![Frontier logo]()
$148
This Priceline deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:33 pm
CLT
- STL
1 stop7h 52m
Frontier
Mon 4/134:59 pm
STL
- CLT
1 stop6h 37m
Frontier
Deal found 3/9![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:47 pm
RDU
- STL
1 stop16h 01m
Frontier
Mon 4/134:59 pm
STL
- RDU
1 stop18h 36m
Frontier
Deal found 3/5![Frontier logo]()
$171
This Travelocity deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
RDU
- STL
1 stop18h 25m
Frontier
Fri 4/178:06 pm
STL
- RDU
1 stop23h 58m
Frontier
Deal found 3/10![Frontier logo]()
$180
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:10 am
RDU
- MCI
1 stop5h 48m
Frontier
Sun 4/1911:53 am
MCI
- RDU
1 stop10h 47m
Frontier
Deal found 3/5![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:09 pm
CLT
- STL
1 stop28h 10m
Frontier
Fri 4/248:06 pm
STL
- CLT
1 stop19h 50m
Frontier
Deal found 3/5![Frontier logo]()
$171
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:30 pm
CLT
- STL
1 stop26h 02m
Frontier
Sun 4/264:59 pm
STL
- CLT
1 stop15h 28m
Frontier
Deal found 3/7![Frontier logo]()
$170
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:51 pm
RDU
- STL
1 stop6h 28m
Frontier
Sun 4/2611:44 am
STL
- RDU
1 stop10h 11m
Frontier
Deal found 3/5![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/263:42 pm
RDU
- STL
1 stop16h 08m
Frontier
Sat 5/28:23 pm
STL
- RDU
1 stop11h 00m
Frontier
Deal found 3/9![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:27 am
ORF
- STL
1 stop20h 23m
Frontier
Thu 4/3011:21 am
STL
- ORF
1 stop21h 56m
Frontier
Deal found 3/10![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:10 am
RDU
- STL
1 stop5h 16m
Frontier
Mon 5/48:23 pm
STL
- RDU
1 stop17h 41m
Frontier
Deal found 3/9![Frontier logo]()
$159
One-way flights from North Carolina to MissouriSearch for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/63:57 pm
RDU
- STL
1 stop19h 33m
Frontier
Deal found 3/6![Frontier logo]()
$64
This Trip.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/304:06 pm
RDU
- STL
1 stop19h 26m
Frontier
Deal found 3/5![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
RDU
- STL
1 stop5h 30m
Frontier
Deal found 3/6![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
RDU
- STL
1 stop25h 50m
Frontier
Deal found 3/5![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:10 am
RDU
- STL
1 stop25h 40m
Frontier
Deal found 3/6![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:50 am
RDU
- STL
1 stop28h 41m
Frontier
Deal found 3/5![Frontier logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
RDU
- STL
1 stop12h 34m
Frontier
Deal found 3/6![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
RDU
- STL
1 stop12h 34m
Frontier
Deal found 3/6![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:32 am
ORF
- STL
1 stop20h 18m
Frontier
Deal found 3/6![Frontier logo]()
$78
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:30 pm
CLT
- STL
1 stop6h 49m
Frontier
Deal found 3/5![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
RDU
- MCI
1 stop5h 18m
Frontier
Deal found 3/6![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:46 pm
RDU
- STL
1 stop7h 39m
Frontier
Deal found 3/5![Frontier logo]()
$80
Find flight deals from North Carolina to Missouri
Keep the following information in mind while searching for North Carolina to Missouri flight deals. Data was last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $136 (Kiwi.com) |
One-way from | $64 (Kiwi.com) |
Popular in | September |
Cheapest in | October |
Average price | $403 |
Good round-trip deal | $305 or less |
Good one-way deal | $154 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from North Carolina to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/8
8:00 am-3:15 pm
2 stops8h 15m
Lambert-St Louis
Wed 4/15
12:40 pm-9:40 pm
2 stops8h 00m
$227
Quickest round-trip
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/29
9:36 am-1:05 pm
1 stop4h 29m
Lambert-St Louis
Mon 5/4
4:41 pm-9:27 pm
1 stop3h 46m
$234
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/8
8:00 am-3:15 pm
2 stops8h 15m
Lambert-St Louis
Mon 4/13
1:45 pm-10:40 pm
2 stops7h 55m
$238
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Thu 4/30
8:30 pm-11:15 pm
1 stop3h 45m
Lambert-St Louis
Sat 5/2
5:40 am-3:10 pm
2 stops8h 30m
$244
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/29
9:36 am-1:05 pm
1 stop4h 29m
Lambert-St Louis
Thu 5/7
6:00 am-11:06 am
1 stop4h 06m
$253
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/22
6:00 am-9:42 am
1 stop4h 42m
Lambert-St Louis
Thu 4/23
6:50 pm-11:53 pm
1 stop4h 03m
$258
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/29
9:36 am-1:05 pm
1 stop4h 29m
Lambert-St Louis
Sun 5/3
6:50 pm-11:53 pm
1 stop4h 03m
$261
KnoxvilleSt. Louis
TYS - STL
TYSSTL
Knoxville McGhee Tyson
Thu 4/2
7:25 pm-12:05 am
1 stop5h 40m
Lambert-St Louis
Thu 4/9
10:50 am-8:20 pm
2 stops8h 30m
$262
CharlotteSt. Louis
CLT - STL
CLTSTL
Charlotte Douglas
Wed 4/29
6:40 am-1:00 pm
2 stops7h 20m
Lambert-St Louis
Thu 4/30
4:00 pm-9:40 pm
1 stop4h 40m
$263
CharlotteKansas City
CLT - MCI
CLTMCI
Charlotte Douglas
Sat 4/11
7:05 am-12:05 pm
1 stop6h 00m
Kansas City
Wed 4/15
3:30 pm-8:55 pm
1 stop4h 25m
$271
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from North Carolina to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from North Carolina with our price prediction graph.
RDU-STL
ORF-STL
CLT-STL
RDU-MCI
RDU-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Missouri
USNC-USMO
RDU-STL
ORF-STL
CLT-STL
RDU-MCI
What is the cheapest month to book a flight from North Carolina to Missouri?
Currently, May is the cheapest month in which you can book a flight from North Carolina to Missouri (average of $88). Flying from North Carolina to Missouri in March is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to MO?
Find hourly flight availability from North Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 10, 2026.
When flying from North Carolina to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 4% versus a flight in the evening.
What is the cheapest day to fly from North Carolina to Missouri?
Use this chart to determine the cheapest time to fly round-trip from North Carolina to Missouri. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their North Carolina to Missouri flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from North Carolina to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 10, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from North Carolina to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for North Carolina to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from North Carolina to Missouri by cabin class
Find flights from North Carolina to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
North Carolina and Missouri flights
Browse other North Carolina and Missouri flight options. Last updated on March 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to North Carolina after your stay in Missouri
North Carolina to Missouri flights
Consider these flights traveling from North Carolina to Missouri.
Top 5 airlines flying from North Carolina to Missouri
Discover the top 5 airlines that operate flights from North Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$234 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$147 | Average$323 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$176 | Average$390 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$371 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$196 | Average$318 | FlexibilityNo cancel fee | On-time69% |