HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$60+ Cheap flights from North Carolina to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STL
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from North Carolina to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from North Carolina to Missouri

Cheapest flights from North Carolina to Missouri
Explore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:26 pmCLT - STL
Nonstop2h 04mAmerican Airlines
Sat 1/108:13 amSTL - CLT
Nonstop1h 58mAmerican Airlines
Deal found 12/26$252
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:42 amCLT - MCI
Nonstop2h 44mAmerican Airlines
Thu 1/112:16 pmMCI - CLT
Nonstop2h 15mAmerican Airlines
Deal found 12/27$263
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:00 pmGSO - STL
1 stop5h 04mDelta
Sat 1/36:29 amSTL - GSO
1 stop4h 23mDelta
Deal found 12/27$271
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:15 pmCLT - STL
1 stop5h 13mDelta
Sat 1/35:55 amSTL - CLT
1 stop3h 58mDelta
Deal found 12/27$272
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:15 pmCLT - STL
Nonstop1h 59mAmerican Airlines
Fri 1/27:05 amSTL - CLT
Nonstop2h 02mAmerican Airlines
Deal found 12/27$276
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:21 amGSO - STL
2 stops8h 02mAmerican Airlines
Sat 1/35:00 amSTL - GSO
1 stop6h 11mAmerican Airlines
Deal found 12/27$276
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:02 amCLT - STL
1 stop7h 52mUnited Airlines
Sat 1/109:57 amSTL - CLT
2 stops8h 00mUnited Airlines
Deal found 12/26$277
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:00 pmGSO - STL
1 stop5h 04mDelta
Sun 1/46:29 amSTL - GSO
1 stop4h 23mDelta
Deal found 12/27$277
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amGSO - STL
2 stops7h 36mAmerican Airlines
Sun 1/45:00 amSTL - GSO
1 stop4h 54mAmerican Airlines
Deal found 12/27$282
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amCLT - MCI
1 stop6h 36mDelta
Thu 1/16:30 amMCI - CLT
1 stop4h 55mDelta
Deal found 12/27$283
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:15 amCLT - STL
1 stop5h 06mDelta
Fri 1/26:29 amSTL - CLT
1 stop4h 56mDelta
Deal found 12/27$296
This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:02 amCLT - STL
1 stop6h 25mUnited Airlines
Fri 1/23:10 pmSTL - CLT
2 stops7h 49mUnited Airlines
Deal found 12/27$301

Find flight deals from North Carolina to Missouri

Keep the following information in mind while searching for North Carolina to Missouri flight deals. Data was last updated December 28, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$145
(Expedia)

One-way from

$60
(Trip.com)

Popular in

September

Cheapest in

January

Average price

$374

Good round-trip deal

$209 or less

Good one-way deal

$148 or less
Provider with most accurate pricing for Raleigh-Durham-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Lambert-St Louis flights.
Search Deals
From North Carolina to Missouri
Search Deals
One-way flight from North Carolina to Missouri
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($4 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($3 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from North Carolina to Missouri.
Search Deals
Price to beat on a one-way flight from North Carolina to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from North Carolina to Missouri that are best for you.

Fly from

North Carolina

Fly to

Missouri

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 1/21

6:01 pm-11:33 pm

1 stop6h 32m

Lambert-St Louis

Wed 1/28

5:42 pm-4:54 pm

1 stop22h 12m

$132

RaleighSt. Louis

RDU - STL

RDUSTL

Raleigh-Durham

Thu 1/22

9:36 pm-10:23 am

1 stop13h 47m

Lambert-St Louis

Mon 1/26

5:42 pm-1:59 pm

1 stop19h 17m

$152

RaleighSt. Louis

RDU - STL

RDUSTL

Raleigh-Durham

Thu 1/22

6:10 am-11:33 pm

2 stops18h 23m

Lambert-St Louis

Mon 1/26

5:42 pm-1:59 pm

1 stop19h 17m

$185

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Fri 2/6

6:02 pm-10:31 am

1 stop17h 29m

Kansas City

Wed 2/11

5:48 pm-4:18 pm

1 stop21h 30m

$186

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sat 2/7

7:43 pm-10:31 am

1 stop15h 48m

Kansas City

Mon 2/9

11:26 am-9:17 pm

1 stop8h 51m

$186

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Fri 2/6

6:02 pm-10:31 am

1 stop17h 29m

Kansas City

Mon 2/9

11:26 am-9:17 pm

1 stop8h 51m

$188

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sat 1/24

7:43 pm-10:31 am

1 stop15h 48m

Kansas City

Mon 1/26

11:26 am-9:17 pm

1 stop8h 51m

$193

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sat 1/31

10:55 am-7:51 pm

2 stops33h 56m

Kansas City

Thu 2/5

11:26 am-8:55 pm

1 stop8h 29m

$194

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Wed 2/25

1:24 pm-10:30 am

1 stop22h 06m

Kansas City

Mon 3/2

11:26 am-8:26 am

1 stop20h 00m

$195

RaleighSt. Louis

RDU - STL

RDUSTL

Raleigh-Durham

Sun 2/1

9:56 pm-9:21 am

1 stop12h 25m

Lambert-St Louis

Mon 2/9

10:16 am-9:01 pm

1 stop9h 45m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from North Carolina to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Missouri

What is the cheapest month to book a flight from North Carolina to Missouri?

Currently, May is the cheapest month in which you can book a flight from North Carolina to Missouri (average of $88). Flying from North Carolina to Missouri in April is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to MO?

Find hourly flight availability from North Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 28, 2025.

When flying from North Carolina to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 4% versus a flight in the evening.

What is the cheapest day to fly from North Carolina to Missouri?

Use this chart to determine the cheapest time to fly round-trip from North Carolina to Missouri. Price data was last updated on December 27, 2025.

Travelers seeking maximum savings on their North Carolina to Missouri flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 28, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from North Carolina to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,256 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,256 reviews
Southwest
8.0
Very good
4,256 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,019 reviews
Southwest
8.0
Very good
4,256 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,113 reviews
Southwest
8.0
Very good
4,256 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,072 reviews
Southwest
8.0
Very good
4,256 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.8
Fair
3,065 reviews
Southwest
8.0
Very good
4,256 reviews

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this North Carolina to Missouri flight route?

    This flight path from North Carolina to Missouri was viewed by 29 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from North Carolina to Missouri?

    Frontier, Delta, and Southwest can get you from North Carolina to Missouri in just under 2h 55m. Your travel time can differ by up to 10h 52m. Airlines will cover a distance of 902 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Missouri one-way?

    The cheapest airlines for a one-way flight from North Carolina to Missouri are Frontier ($55), Delta ($88), and Southwest ($98).

  • Can I find deals for flights from North Carolina to Missouri that include hotel bookings?

    Yes. In addition to deals on North Carolina to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Missouri.

  • Can I find deals for business class flights from North Carolina to Missouri?

    Yes. Cheapflights offers flight deals from North Carolina to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Missouri?

    Currently, May is the cheapest month in which you can book a flight from North Carolina to Missouri (average of $88). Flying from North Carolina to Missouri in April is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Miami flights
John F Kennedy Intl to Fort Lauderdale flights
Newark to Fort Lauderdale flights
LaGuardia to Miami flights
LaGuardia to Fort Lauderdale flights
Newark to Miami flights
John F Kennedy Intl to Las Vegas flights
John F Kennedy Intl to Los Angeles flights
Los Angeles to John F Kennedy Intl flights
Newark to West Palm Beach flights
Newark to Las Vegas flights
John F Kennedy Intl to Orlando flights
Newark to Orlando flights
Dallas/Fort Worth to Las Vegas flights
O'Hare Intl to Las Vegas flights
Dallas/Fort Worth to LaGuardia flights
LaGuardia to Orlando flights
San Francisco to Las Vegas flights
Dallas/Fort Worth to John F Kennedy Intl flights
Minneapolis to Sky Harbor Intl flights
Seattle to Los Angeles flights
Seattle to Las Vegas flights
John F Kennedy Intl to West Palm Beach flights
O'Hare Intl to John F Kennedy Intl flights
Los Angeles to Honolulu flights
Boston to Fort Lauderdale flights
Newark to Los Angeles flights
Los Angeles to Newark flights
Miami to John F Kennedy Intl flights
Los Angeles to Seattle flights
John F Kennedy Intl to Dallas/Fort Worth flights
LaGuardia to West Palm Beach flights
Dallas/Fort Worth to Newark flights
O'Hare Intl to Sky Harbor Intl flights
Dallas/Fort Worth to O'Hare Intl flights
Dulles Intl to Miami flights
Boston to Orlando flights
O'Hare Intl to Los Angeles flights
John F Kennedy Intl to Sky Harbor Intl flights
Detroit to Orlando flights
LaGuardia to Tampa flights
Boston to Miami flights
Detroit to Fort Lauderdale flights
O'Hare Intl to Orlando flights
Baltimore to Fort Lauderdale flights
Fort Lauderdale to John F Kennedy Intl flights
O'Hare Intl to Dallas/Fort Worth flights
Reagan-National to Miami flights
Dallas/Fort Worth to Denver flights
Dulles Intl to Las Vegas flights

Top 6 airlines flying from North Carolina to Missouri

Discover the top 6 airlines that operate flights from North Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$133Average$235FlexibilityNo cancel feeOn-time62%
DeltaCheapest$149Average$327FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$176Average$394FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$196Average$370FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$196Average$364FlexibilityNo cancel feeOn-time69%
Spirit AirlinesCheapest$218Average$356FlexibilityNo cancel feeOn-time65%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.