$61+ Cheap flights from North Carolina to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STL
Mar 10 — Mar 171
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from North Carolina to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from North Carolina to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from North Carolina to MissouriExplore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.
Explore the most affordable flight options available from North Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:46 pm
CLT
- STL
1 stop8h 41m
Frontier
Sun 3/13:49 pm
STL
- CLT
1 stop24h 07m
Frontier
Deal found 2/4![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:53 pm
RDU
- STL
1 stop8h 34m
Frontier
Wed 3/1111:32 am
STL
- RDU
1 stop11h 14m
Frontier
Deal found 2/7![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:46 pm
CLT
- STL
1 stop8h 41m
Multiple Airlines
Mon 3/23:49 pm
STL
- CLT
1 stop24h 05m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:10 am
RDU
- STL
1 stop25h 41m
Frontier
Mon 2/238:22 pm
STL
- RDU
1 stop26h 48m
Frontier
Deal found 2/7![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:46 pm
CLT
- STL
1 stop8h 41m
Frontier
Mon 3/94:51 pm
STL
- CLT
1 stop14h 12m
Frontier
Deal found 2/5![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:50 pm
RDU
- STL
1 stop13h 01m
Frontier
Mon 2/238:22 pm
STL
- RDU
1 stop26h 48m
Frontier
Deal found 2/7![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:00 am
RDU
- STL
1 stop6h 49m
Frontier
Mon 3/94:51 pm
STL
- RDU
1 stop15h 07m
Frontier
Deal found 2/6![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:50 pm
RDU
- MCI
1 stop16h 13m
Frontier
Sun 2/2210:14 am
MCI
- RDU
1 stop12h 56m
Frontier
Deal found 2/6![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:49 pm
CLT
- STL
1 stop7h 38m
Multiple Airlines
Sun 3/13:49 pm
STL
- CLT
1 stop14h 00m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:53 am
CLT
- STL
1 stop16h 34m
Multiple Airlines
Mon 3/23:49 pm
STL
- CLT
1 stop17h 28m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:20 am
RDU
- STL
1 stop25h 31m
Frontier
Sat 2/218:17 pm
STL
- RDU
1 stop26h 53m
Frontier
Deal found 2/7![Frontier logo]()
$154
This CheapOair deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/249:25 pm
RDU
- STL
1 stop26h 02m
Frontier
Tue 3/33:49 pm
STL
- RDU
1 stop27h 41m
Frontier
Deal found 2/4![Frontier logo]()
$155
Best flights from North Carolina to MissouriDiscover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 8, 2026.
Discover carefully curated flight deals from North Carolina to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 8, 2026.
This CheapOair deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/231:12 pm
RDU
- STL
1 stop11h 47m
Frontier
Tue 2/243:49 pm
STL
- RDU
1 stop24h 10m
Frontier
Deal found 2/4![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:08 am
CLT
- MCI
1 stop7h 21m
Multiple Airlines
Tue 3/2412:24 pm
MCI
- CLT
1 stop24h 53m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$176
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:15 pm
MYR
- STL
1 stop6h 53m
United Airlines
Mon 4/207:45 am
STL
- MYR
1 stop5h 32m
United Airlines
Deal found 2/7![United Airlines logo]()
$192
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:52 pm
MYR
- STL
1 stop7h 07m
American Airlines
Mon 4/206:55 pm
STL
- MYR
1 stop4h 02m
American Airlines
Deal found 2/7![American Airlines logo]()
$197
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:20 am
RDU
- STL
1 stop3h 47m
Delta
Tue 6/235:30 pm
STL
- RDU
1 stop5h 56m
Delta
Deal found 2/6![Delta logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:00 pm
CLT
- MCI
1 stop15h 29m
Spirit Airlines
Tue 3/2412:24 pm
MCI
- CLT
1 stop11h 14m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$203
This Southwest deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:15 pm
TYS
- STL
1 stop6h 55m
Southwest
Tue 4/215:45 am
STL
- TYS
1 stop7h 35m
Southwest
Deal found 2/6![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:28 pm
CLT
- MCI
1 stop19h 01m
Multiple Airlines
Wed 3/2512:24 pm
MCI
- CLT
1 stop6h 53m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$177
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:14 pm
MYR
- STL
1 stop6h 54m
United Airlines
Sun 5/107:45 am
STL
- MYR
1 stop5h 33m
United Airlines
Deal found 2/8![United Airlines logo]()
$192
This CheapOair deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:38 pm
RDU
- STL
1 stop25h 41m
Frontier
Sun 5/34:55 pm
STL
- RDU
1 stop14h 01m
Frontier
Deal found 2/7![Frontier logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/293:30 pm
RDU
- MCI
1 stop9h 29m
Multiple Airlines
Sat 5/26:00 am
MCI
- RDU
1 stop9h 56m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$178
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:38 am
RDU
- STL
1 stop5h 08m
Delta
Sun 4/56:32 am
STL
- RDU
1 stop4h 32m
Delta
Deal found 2/6![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:26 pm
MYR
- STL
1 stop5h 26m
American Airlines
Mon 2/232:19 pm
STL
- MYR
2 stops8h 36m
American Airlines
Deal found 2/8![American Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:08 am
CLT
- MCI
1 stop7h 21m
Multiple Airlines
Wed 3/2512:24 pm
MCI
- CLT
1 stop6h 53m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$178
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:20 am
RDU
- STL
1 stop3h 47m
Delta
Tue 6/236:45 am
STL
- RDU
1 stop3h 57m
Delta
Deal found 2/6![Delta logo]()
$197
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:20 pm
RDU
- STL
1 stop4h 48m
United Airlines
Tue 5/510:00 am
STL
- RDU
1 stop6h 23m
United Airlines
Deal found 2/6![United Airlines logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2211:32 am
ORF
- STL
1 stop20h 19m
Frontier
Thu 2/2610:11 pm
STL
- ORF
2 stops40h 41m
Frontier
Deal found 2/7![Frontier logo]()
$204
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/219:10 am
MYR
- STL
1 stop4h 32m
American Airlines
Wed 2/256:06 am
STL
- MYR
1 stop4h 33m
American Airlines
Deal found 2/6![American Airlines logo]()
$205
This CheapOair deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
CLT
- MCI
1 stop6h 29m
Spirit Airlines
Wed 4/156:00 am
MCI
- CLT
1 stop27h 17m
Spirit Airlines
Deal found 2/5![Spirit Airlines logo]()
$230
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:20 am
RDU
- STL
1 stop3h 47m
Delta
Sat 6/273:42 pm
STL
- RDU
1 stop5h 08m
Delta
Deal found 2/6![Delta logo]()
$197
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:13 pm
RDU
- STL
1 stop4h 58m
United Airlines
Thu 6/256:00 am
STL
- RDU
1 stop5h 33m
United Airlines
Deal found 2/7![United Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:10 am
MYR
- STL
1 stop4h 25m
American Airlines
Tue 2/249:23 am
STL
- MYR
2 stops8h 14m
American Airlines
Deal found 2/5![American Airlines logo]()
$210
This Southwest deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:15 pm
TYS
- STL
1 stop6h 55m
Southwest
Sun 5/107:35 am
STL
- TYS
1 stop3h 05m
Southwest
Deal found 2/5![Southwest logo]()
$257
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:13 pm
CLT
- STL
1 stop20h 56m
Frontier
Sun 3/13:49 pm
STL
- CLT
1 stop14h 00m
Frontier
Deal found 2/8![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:00 pm
CLT
- MCI
1 stop15h 29m
Spirit Airlines
Mon 3/2312:24 pm
MCI
- CLT
1 stop11h 14m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$235
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/278:00 am
RDU
- STL
1 stop5h 11m
United Airlines
Tue 6/308:15 am
STL
- RDU
1 stop4h 46m
United Airlines
Deal found 2/6![United Airlines logo]()
$197
This Delta deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2012:40 pm
RDU
- STL
1 stop4h 18m
Delta
Mon 6/225:30 pm
STL
- RDU
1 stop4h 20m
Delta
Deal found 2/6![Delta logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:59 pm
CLT
- MCI
1 stop10h 54m
Multiple Airlines
Fri 3/2712:24 pm
MCI
- CLT
1 stop11h 14m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:00 pm
CLT
- MCI
1 stop15h 29m
Spirit Airlines
Thu 3/1912:24 pm
MCI
- CLT
1 stop11h 14m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:45 pm
TYS
- STL
1 stop5h 30m
Southwest
Wed 5/610:25 am
STL
- TYS
2 stops9h 25m
Southwest
Deal found 2/5![Southwest logo]()
$261
Last-minute flights from North Carolina to MissouriDiscover last-minute flight deals from North Carolina to Missouri. Data last updated February 8, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to Missouri. Data last updated February 8, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:20 am
RDU
- STL
1 stop25h 31m
Frontier
Sat 2/218:17 pm
STL
- RDU
1 stop26h 53m
Frontier
Deal found 2/7![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:50 pm
RDU
- STL
1 stop13h 01m
Frontier
Mon 2/238:22 pm
STL
- RDU
1 stop26h 48m
Frontier
Deal found 2/7![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:50 pm
RDU
- MCI
1 stop16h 13m
Frontier
Sun 2/2210:14 am
MCI
- RDU
1 stop12h 56m
Frontier
Deal found 2/6![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:10 am
RDU
- STL
1 stop25h 41m
Frontier
Mon 2/238:22 pm
STL
- RDU
1 stop26h 48m
Frontier
Deal found 2/7![Frontier logo]()
$133
This CheapOair deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/249:25 pm
RDU
- STL
1 stop26h 02m
Frontier
Tue 3/33:49 pm
STL
- RDU
1 stop27h 41m
Frontier
Deal found 2/4![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:46 pm
CLT
- STL
1 stop8h 41m
Frontier
Sun 3/13:49 pm
STL
- CLT
1 stop24h 07m
Frontier
Deal found 2/4![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:46 pm
CLT
- STL
1 stop8h 41m
Multiple Airlines
Mon 3/23:49 pm
STL
- CLT
1 stop24h 05m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:49 pm
CLT
- STL
1 stop7h 38m
Multiple Airlines
Sun 3/13:49 pm
STL
- CLT
1 stop14h 00m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:53 am
CLT
- STL
1 stop16h 34m
Multiple Airlines
Mon 3/23:49 pm
STL
- CLT
1 stop17h 28m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:53 pm
RDU
- STL
1 stop8h 34m
Frontier
Wed 3/1111:32 am
STL
- RDU
1 stop11h 14m
Frontier
Deal found 2/7![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:46 pm
CLT
- STL
1 stop8h 41m
Frontier
Mon 3/94:51 pm
STL
- CLT
1 stop14h 12m
Frontier
Deal found 2/5![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:00 am
RDU
- STL
1 stop6h 49m
Frontier
Mon 3/94:51 pm
STL
- RDU
1 stop15h 07m
Frontier
Deal found 2/6![Frontier logo]()
$147
One-way flights from North Carolina to MissouriSearch for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated February 8, 2026.
Search for one-way flight options from North Carolina to Missouri. Find affordable one-way fares based on user searches. Data last updated February 8, 2026.
This Trip.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:54 pm
RDU
- STL
1 stop12h 57m
Frontier
Deal found 2/7![Frontier logo]()
$61
This Trip.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:10 am
RDU
- STL
1 stop25h 41m
Frontier
Deal found 2/4![Frontier logo]()
$62
This Priceline deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:46 pm
CLT
- STL
1 stop8h 41m
Frontier
Deal found 2/5![Frontier logo]()
$64
This Priceline deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:54 pm
RDU
- STL
1 stop5h 33m
Frontier
Deal found 2/4![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:54 pm
RDU
- STL
1 stop12h 57m
Frontier
Deal found 2/4![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/39:25 pm
RDU
- STL
1 stop26h 02m
Frontier
Deal found 2/6![Frontier logo]()
$67
This WAYA deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:00 am
RDU
- STL
1 stop6h 49m
Frontier
Deal found 2/6![Frontier logo]()
$70
This WAYA deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:50 am
RDU
- STL
1 stop4h 47m
Frontier
Deal found 2/6![Frontier logo]()
$72
This Trip.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:50 pm
RDU
- STL
1 stop13h 01m
Frontier
Deal found 2/8![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:10 am
RDU
- STL
1 stop25h 41m
Frontier
Deal found 2/5![Frontier logo]()
$74
This Trip.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:30 pm
RDU
- MCI
1 stop18h 23m
Frontier
Deal found 2/7![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 am
RDU
- STL
1 stop5h 31m
Frontier
Deal found 2/6![Frontier logo]()
$78
Find flight deals from North Carolina to Missouri
Keep the following information in mind while searching for North Carolina to Missouri flight deals. Data was last updated February 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $131 (Kiwi.com) |
One-way from | $61 (Trip.com) |
Popular in | June |
Cheapest in | October |
Average price | $384 |
Good round-trip deal | $219 or less |
Good one-way deal | $168 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from North Carolina to Missouri that are best for you.
Fly from
North Carolina
Fly to
Missouri
Route
Depart
Return
Price
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Mon 2/23
1:12 pm-11:59 pm
1 stop11h 47m
Lambert-St Louis
Tue 2/24
3:49 pm-4:59 pm
1 stop24h 10m
$171
CharlotteKansas City
CLT - MCI
CLTMCI
Charlotte Douglas
Wed 3/11
9:08 am-3:29 pm
1 stop7h 21m
Kansas City
Tue 3/24
12:24 pm-2:17 pm
1 stop24h 53m
$176
CharlotteKansas City
CLT - MCI
CLTMCI
Charlotte Douglas
Mon 3/9
9:28 pm-3:29 pm
1 stop19h 01m
Kansas City
Wed 3/25
12:24 pm-8:17 pm
1 stop6h 53m
$177
RaleighKansas City
RDU - MCI
RDUMCI
Raleigh-Durham
Wed 4/29
3:30 pm-11:59 pm
1 stop9h 29m
Kansas City
Sat 5/2
6:00 am-4:56 pm
1 stop9h 56m
$178
CharlotteKansas City
CLT - MCI
CLTMCI
Charlotte Douglas
Wed 3/11
9:08 am-3:29 pm
1 stop7h 21m
Kansas City
Wed 3/25
12:24 pm-8:17 pm
1 stop6h 53m
$178
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Fri 4/17
3:15 pm-9:08 pm
1 stop6h 53m
Lambert-St Louis
Mon 4/20
7:45 am-2:17 pm
1 stop5h 32m
$192
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Thu 5/7
3:14 pm-9:08 pm
1 stop6h 54m
Lambert-St Louis
Sun 5/10
7:45 am-2:18 pm
1 stop5h 33m
$192
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Thu 4/30
10:38 pm-11:19 pm
1 stop25h 41m
Lambert-St Louis
Sun 5/3
4:55 pm-7:56 am
1 stop14h 01m
$192
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Fri 4/17
4:52 pm-10:59 pm
1 stop7h 07m
Lambert-St Louis
Mon 4/20
6:55 pm-11:57 pm
1 stop4h 02m
$197
RaleighSt. Louis
RDU - STL
RDUSTL
Raleigh-Durham
Sun 6/21
5:20 am-8:07 am
1 stop3h 47m
Lambert-St Louis
Tue 6/23
5:30 pm-12:26 am
1 stop5h 56m
$197
Showing 1-10 of 60 results
Best time to book a flight from North Carolina to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from North Carolina with our price prediction graph.
RDU-STL
CLT-MCI
MYR-STL
TYS-STL
RDU-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Missouri
USNC-USMO
RDU-STL
CLT-MCI
MYR-STL
TYS-STL
What is the cheapest month to book a flight from North Carolina to Missouri?
Currently, May is the cheapest month in which you can book a flight from North Carolina to Missouri (average of $88). Flying from North Carolina to Missouri in April is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to MO?
Find hourly flight availability from North Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 8, 2026.
When flying from North Carolina to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 4% versus a flight in the evening.
What is the cheapest day to fly from North Carolina to Missouri?
Use this chart to determine the cheapest time to fly round-trip from North Carolina to Missouri. Price data was last updated on January 31, 2026.
Travelers seeking maximum savings on their North Carolina to Missouri flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 8, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from North Carolina to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for North Carolina to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from North Carolina to Missouri by cabin class
Find flights from North Carolina to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
North Carolina and Missouri flights
Browse other North Carolina and Missouri flight options. Last updated on February 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to North Carolina after your stay in Missouri
North Carolina to Missouri flights
Consider these flights traveling from North Carolina to Missouri.
Top 5 airlines flying from North Carolina to Missouri
Discover the top 5 airlines that operate flights from North Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$118 | Average$328 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$141 | Average$258 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$176 | Average$390 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$361 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$223 | Average$359 | FlexibilityNo cancel fee | On-time69% |