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$154+ Cheap flights from Des Moines to Memphis (DSM - MEM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEM
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Des Moines to Memphis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Memphis (MEM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$241
(Delta)

One-way from

$154
(Delta)

Popular in

March

Cheapest in

June

Average price

$326
From Des Moines to Memphis
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One-way flight from Des Moines to Memphis
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Highest demand for flights based on searches. 22% potential increase in price ($121 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Des Moines to Memphis

Cheapest flights from Des Moines to Memphis
Explore the most affordable flight options available from Des Moines to Memphis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/117:08 amDSM - MEM
1 stop6h 31mAmerican Airlines
Thu 9/1810:49 amMEM - DSM
1 stop4h 29mAmerican Airlines
Deal found 7/28$306
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/292:49 pmDSM - MEM
1 stop7h 28mDelta
Sun 9/145:20 amMEM - DSM
1 stop5h 20mDelta
Deal found 7/28$307
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/117:00 amDSM - MEM
2 stops28h 53mMultiple Airlines
Thu 9/188:35 pmMEM - DSM
2 stops18h 05mMultiple Airlines
Deal found 7/28$324
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/251:10 pmDSM - MEM
2 stops8h 27mUnited Airlines
Fri 8/297:30 amMEM - DSM
1 stop4h 53mUnited Airlines
Deal found 7/26$418
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/297:00 amDSM - MEM
2 stops10h 25mSouthwest
Sun 9/147:55 amMEM - DSM
1 stop7h 45mSouthwest
Deal found 7/28$449

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Des Moines

Fly to

Memphis

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 8/21

6:00 am-1:23 pm

1 stop7h 23m

Memphis

Fri 8/22

11:10 am-5:45 pm

1 stop6h 35m

$241

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 9/26

3:50 pm-10:59 pm

2 stops7h 09m

Memphis

Mon 9/29

6:08 pm-11:06 pm

1 stop4h 58m

$288

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 9/11

7:00 am-11:53 am

2 stops28h 53m

Memphis

Thu 9/18

8:35 pm-2:40 pm

2 stops18h 05m

$324

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 8/21

6:00 am-2:02 pm

2 stops8h 02m

Memphis

Fri 8/22

7:30 am-2:10 pm

1 stop6h 40m

$396

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 8/29

7:00 am-5:25 pm

2 stops10h 25m

Memphis

Sun 9/14

7:55 am-3:40 pm

1 stop7h 45m

$449

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 9/11

6:30 pm-11:03 pm

1 stop4h 33m

$154

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 9/11

7:08 am-1:58 pm

2 stops6h 50m

$229

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 9/11

11:35 am-9:15 am

3 stops21h 40m

$454

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Des Moines to Memphis

Have a flexible travel schedule? Discover the best time to fly to Memphis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Memphis

What is the cheapest month to book a flight from Des Moines to Memphis?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Memphis (average of $310). Flying from Des Moines to Memphis in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MEM?

Find hourly flight availability from Des Moines to Memphis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

It’s typically best to fly out from Des Moines to Memphis in the afternoon. Doing so could potentially save you 13% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Memphis

Get insights into the airlines that provide service to Memphis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Memphis. Reviews last updated July 29, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Des Moines to Memphis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,977 reviews
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,899 reviews
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Memphis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Memphis round-trip?

    Our cheapest airline available from Des Moines to Memphis is Delta. Our recent data shows that you can find tickets from as low as $241 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $288 and $396 round-trip. You may be able to fly from Des Moines to Memphis for 41% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Des Moines to Memphis one-way?

    The cheapest airlines for a one-way flight from Des Moines to Memphis are Delta ($154), American Airlines ($229), and United Airlines ($454).

  • Can I find deals for flights from Des Moines to Memphis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Memphis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Memphis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Memphis.

  • Can I find deals for business class flights from Des Moines to Memphis?

    Yes. Cheapflights offers flight deals from Des Moines to Memphis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Memphis?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Memphis (average of $310). Flying from Des Moines to Memphis in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Batesville
Southaven
West Memphis
Forrest City
Germantown
Cordova
Marion
Horn Lake

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Top 2 airlines flying from Des Moines to Memphis

Discover the top 2 airlines that operate flights from Des Moines to Memphis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$246Average$426FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$252Average$346FlexibilityNo cancel feeOn-time71%

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