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$259+ Cheap flights from Des Moines to Memphis (DSM - MEM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEM
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from Des Moines to Memphis

Cheapest flights from Des Moines to Memphis
Explore the most affordable flight options available from Des Moines to Memphis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:55 pmDSM - MEM
1 stop4h 26mDelta
lun. 12/295:55 amMEM - DSM
1 stop5h 33mDelta
Deal found 12/10$318
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/252:07 pmDSM - MEM
1 stop5h 32mAmerican Airlines
lun. 12/295:00 amMEM - DSM
2 stops7h 54mAmerican Airlines
Deal found 12/11$323
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/248:31 amDSM - MEM
2 stops34h 36mMultiple Airlines
mar. 12/308:47 pmMEM - DSM
1 stop16h 08mMultiple Airlines
Deal found 12/11$348
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/248:31 amDSM - MEM
2 stops34h 36mMultiple Airlines
lun. 12/295:54 pmMEM - DSM
1 stop21h 37mMultiple Airlines
Deal found 12/11$367
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/252:07 pmDSM - MEM
1 stop5h 32mAmerican Airlines
dom. 12/287:04 amMEM - DSM
1 stop5h 50mAmerican Airlines
Deal found 12/11$378
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/248:31 amDSM - MEM
2 stops34h 36mMultiple Airlines
dom. 12/288:17 pmMEM - DSM
1 stop13h 46mMultiple Airlines
Deal found 12/11$384
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/266:59 amDSM - MEM
1 stop4h 34mDelta
lun. 12/295:55 amMEM - DSM
1 stop5h 33mDelta
Deal found 12/11$407
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/245:06 pmDSM - MEM
1 stop5h 23mUnited Airlines
dom. 12/287:30 amMEM - DSM
1 stop7h 03mUnited Airlines
Deal found 12/11$408
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/253:14 pmDSM - MEM
1 stop6h 44mUnited Airlines
mar. 12/3011:25 amMEM - DSM
2 stops10h 15mUnited Airlines
Deal found 12/11$423
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/263:14 pmDSM - MEM
1 stop6h 44mUnited Airlines
dom. 12/287:30 amMEM - DSM
1 stop7h 03mUnited Airlines
Deal found 12/11$467
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/263:14 pmDSM - MEM
1 stop6h 44mUnited Airlines
mar. 12/306:30 amMEM - DSM
2 stops11h 35mUnited Airlines
Deal found 12/11$472

Find flight deals from Des Moines to Memphis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Memphis (MEM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$240
(Delta)

Popular in

March

Cheapest in

June

Average price

$346
Provider with most accurate pricing for Des Moines-Memphis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Memphis flights.
Search Deals
From Des Moines to Memphis
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($110 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($41 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Des Moines

Fly to

Memphis

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

dom. 1/18

6:54 am-11:43 am

1 stop4h 49m

Memphis

jue. 1/22

10:32 am-5:08 pm

1 stop6h 36m

$259

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

dom. 1/18

4:00 pm-10:51 pm

1 stop6h 51m

Memphis

jue. 1/22

8:37 am-4:24 pm

2 stops7h 47m

$264

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

jue. 12/25

3:14 pm-9:58 pm

1 stop6h 44m

Memphis

lun. 12/29

2:48 pm-9:40 pm

1 stop6h 52m

$318

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

jue. 12/25

6:15 am-11:14 am

1 stop4h 59m

Memphis

mar. 12/30

6:00 am-10:38 am

1 stop4h 38m

$318

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

jue. 12/25

5:55 pm-10:21 pm

1 stop4h 26m

Memphis

lun. 12/29

5:55 am-11:28 am

1 stop5h 33m

$318

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

dom. 1/25

2:58 pm-10:49 am

2 stops19h 51m

Memphis

dom. 2/1

8:18 pm-10:19 am

2 stops14h 01m

$319

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

dom. 1/18

8:10 am-1:49 pm

1 stop5h 39m

Memphis

jue. 1/22

5:00 pm-10:30 pm

1 stop5h 30m

$319

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

jue. 12/25

2:07 pm-7:39 pm

1 stop5h 32m

Memphis

lun. 12/29

5:00 am-12:54 pm

2 stops7h 54m

$323

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

dom. 1/25

6:54 am-11:43 am

1 stop4h 49m

Memphis

dom. 2/1

10:32 am-5:08 pm

1 stop6h 36m

$327

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

dom. 12/28

6:52 pm-11:59 pm

1 stop5h 07m

$308

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 11 results
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Compare providers for flights from Des Moines to Memphis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Memphis in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Memphis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Memphis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Memphis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Memphis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Memphis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Memphis

Have a flexible travel schedule? Discover the best time to fly to Memphis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Memphis

Get insights into the airlines that provide service to Memphis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Memphis. Reviews last updated diciembre 12, 2025.
See what other customers who have flown with Delta and American Airlines from Des Moines to Memphis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Memphis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Memphis?

    Delta, American Airlines, and United Airlines can get you from Des Moines to Memphis in just under 4h 49m. Your travel time can differ by up to 2h 02m. Des Moines and Memphis are separated by a distance of 491 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Memphis round-trip?

    Our cheapest airline available from Des Moines to Memphis is American Airlines. Our recent data shows that you can find tickets from as low as $256 on this airline. An additional option worth looking into is Delta, starting at $257. You may be able to fly from Des Moines to Memphis for 39% less than the average price by searching for these airlines.

  • Can I find deals for flights from Des Moines to Memphis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Memphis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Memphis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Memphis.

  • Can I find deals for business class flights from Des Moines to Memphis?

    Yes. Cheapflights offers flight deals from Des Moines to Memphis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Batesville
Southaven
West Memphis
Forrest City
Marion
Germantown
Horn Lake

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Top 2 airlines flying from Des Moines to Memphis

Discover the top 2 airlines that operate flights from Des Moines to Memphis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$256Average$341FlexibilityNo cancel feeOn-time71%
DeltaCheapest$257Average$403FlexibilityNo cancel feeOn-timeN/A

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