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$90+ Cheap flights from Des Moines to Memphis (DSM - MEM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Memphis

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Memphis (MEM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$189
(American Airlines)

One-way from

$90
(Southwest)

Popular in

March

Cheapest in

June

Average price

$335
From Des Moines to Memphis
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One-way flight from Des Moines to Memphis
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Highest demand for flights based on searches. 20% potential increase in price ($109 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Memphis

Cheapest flights from Des Moines to Memphis
Explore the most affordable flight options available from Des Moines to Memphis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:00 amDSM - MEM
1 stop6h 53mAmerican Airlines
Sat 10/186:00 amMEM - DSM
1 stop6h 38mAmerican Airlines
Deal found 9/10$189
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/143:39 pmDSM - MEM
1 stop7h 02mAmerican Airlines
Sat 11/155:15 amMEM - DSM
1 stop5h 25mAmerican Airlines
Deal found 9/9$228
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:00 amDSM - MEM
2 stops15h 25mSouthwest
Sat 11/155:35 amMEM - DSM
2 stops14h 50mSouthwest
Deal found 9/9$269
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:07 pmDSM - MEM
1 stop5h 52mAmerican Airlines
Fri 10/317:00 amMEM - DSM
1 stop4h 22mAmerican Airlines
Deal found 9/8$270
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/132:40 pmDSM - MEM
1 stop7h 16mDelta
Mon 10/206:00 amMEM - DSM
1 stop4h 26mDelta
Deal found 9/9$279
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:26 pmDSM - MEM
1 stop5h 03mAmerican Airlines
Sun 11/165:15 amMEM - DSM
1 stop5h 25mAmerican Airlines
Deal found 9/10$283
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:12 pmDSM - MEM
1 stop4h 45mAmerican Airlines
Tue 9/305:51 pmMEM - DSM
1 stop5h 54mAmerican Airlines
Deal found 9/11$288
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/266:22 pmDSM - MEM
1 stop5h 37mAmerican Airlines
Sun 11/25:15 amMEM - DSM
1 stop5h 25mAmerican Airlines
Deal found 9/11$300
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:20 amDSM - MEM
2 stops8h 15mSouthwest
Sat 10/186:50 amMEM - DSM
1 stop14h 00mSouthwest
Deal found 9/10$308

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.

Fly from

Des Moines

Fly to

Memphis

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 11/17

12:05 pm-9:15 pm

1 stop9h 10m

Memphis

Wed 11/19

7:55 am-3:35 pm

1 stop7h 40m

$211

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 11/22

3:31 pm-10:33 pm

1 stop7h 02m

Memphis

Mon 11/24

6:16 am-12:36 pm

1 stop6h 20m

$218

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 11/11

6:15 am-2:10 pm

2 stops7h 55m

Memphis

Thu 11/13

10:25 am-9:00 pm

1 stop10h 35m

$222

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 11/4

3:15 pm-9:58 pm

1 stop6h 43m

Memphis

Thu 11/6

7:30 am-2:19 pm

1 stop6h 49m

$228

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 11/14

6:00 pm-10:41 pm

1 stop4h 41m

Memphis

Sat 11/15

5:15 am-1:31 pm

1 stop8h 16m

$228

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 11/3

3:15 pm-9:58 pm

1 stop6h 43m

Memphis

Wed 11/5

7:30 am-12:14 pm

1 stop4h 44m

$228

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 11/12

6:15 am-2:10 pm

2 stops7h 55m

Memphis

Fri 11/14

10:25 am-9:00 pm

1 stop10h 35m

$244

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 11/4

8:20 am-5:15 pm

1 stop8h 55m

Memphis

Thu 11/6

2:20 pm-11:35 pm

2 stops9h 15m

$258

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 11/12

12:05 pm-9:15 pm

1 stop9h 10m

$90

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 11/12

9:30 am-2:57 pm

3 stops29h 27m

$228

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 13 results
1
2

Best time to book a flight from Des Moines to Memphis

Have a flexible travel schedule? Discover the best time to fly to Memphis from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Memphis

What is the cheapest time of day to fly from DSM to MEM?

Find hourly flight availability from Des Moines to Memphis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Des Moines to Memphis in the afternoon. Doing so could potentially save you 13% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Memphis

Get insights into the airlines that provide service to Memphis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Memphis. Reviews last updated September 11, 2025.
See what other customers who have flown with Delta and American Airlines from Des Moines to Memphis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Memphis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Memphis?

    Southwest and American Airlines can get you from Des Moines to Memphis in just under 7h 02m. Your travel time can differ by up to 2h 08m. Des Moines and Memphis are separated by a distance of 491 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Memphis round-trip?

    Our cheapest airline available from Des Moines to Memphis is American Airlines. Our recent data shows that you can find tickets from as low as $252 on this airline. An additional option worth looking into is Delta, starting at $257. You may be able to fly from Des Moines to Memphis for 40% less than the average price by searching for these airlines.

  • Can I find deals for flights from Des Moines to Memphis that include hotel bookings?

    Yes. In addition to deals on Des Moines to Memphis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Memphis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Memphis.

  • Can I find deals for business class flights from Des Moines to Memphis?

    Yes. Cheapflights offers flight deals from Des Moines to Memphis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Memphis?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Memphis (average of $310). Flying from Des Moines to Memphis in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Memphis?

Book flights to Memphis if you plan to visit one of these locations
Batesville
Southaven
West Memphis
Forrest City
Cordova
Marion
Germantown
Horn Lake

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Top 2 airlines flying from Des Moines to Memphis

Discover the top 2 airlines that operate flights from Des Moines to Memphis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$252Average$376FlexibilityNo cancel feeOn-time71%
DeltaCheapest$257Average$446FlexibilityNo cancel feeOn-timeN/A

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