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$414+ Cheap flights from Knoxville to Medford (TYS - MFR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MFR
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Knoxville to Medford

Cheapest flights from Knoxville to Medford
Explore the most affordable flight options available from Knoxville to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:40 amTYS - MFR
1 stop7h 45mUnited Airlines
Mon 12/295:00 amMFR - TYS
1 stop14h 29mUnited Airlines
Deal found 12/10$803

Find flight deals from Knoxville to Medford

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$414
(United Airlines)

Popular in

December

Cheapest in

March

Average price

$1,323
Provider with most accurate pricing for Knoxville McGhee Tyson-Medford flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Medford flights.
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From Knoxville McGhee Tyson to Medford
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($140 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($51 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Knoxville

Fly to

Medford

Route

Depart

Return

Price

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 1/24

4:25 pm-9:02 pm

1 stop7h 37m

Medford

Wed 1/28

6:25 pm-10:32 am

2 stops13h 07m

$414

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Thu 12/25

8:40 am-1:25 pm

1 stop7h 45m

Medford

Mon 12/29

5:00 am-10:29 pm

1 stop14h 29m

$803

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Compare providers for flights from Knoxville to Medford

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Medford in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Medford flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Medford flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Medford flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Medford flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Medford flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Medford

Have a flexible travel schedule? Discover the best time to fly to Medford from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Medford

What is the cheapest month to book a flight from Knoxville to Medford?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Medford (average of $216). Flying from Knoxville to Medford in July is currently the most expensive (average of $633). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Medford

Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown United Airlines from Knoxville to Medford. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,095 reviews

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Food

6.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
United Airlines
7.4
Good
9,095 reviews
United Airlines
7.4
Good
9,095 reviews

Overall

7.4

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Food

6.6

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Medford?

    Airlines like United Airlines fly from Knoxville to Medford in about 7h 37m. The time it takes to get you to your destination can typically vary by up to . The distance from Knoxville to Medford is about 2113 mi.

  • What is the cheapest airline to fly from Knoxville to Medford round-trip?

    Cheapflights users have booked flights from Knoxville to Medford round-trip from $462. This flight start at 43% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Medford that include hotel bookings?

    Yes. In addition to deals on Knoxville to Medford flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Medford?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Medford.

  • Can I find deals for business class flights from Knoxville to Medford?

    Yes. Cheapflights offers flight deals from Knoxville to Medford by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Medford?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Medford (average of $216). Flying from Knoxville to Medford in July is currently the most expensive (average of $633). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Yreka

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Top airline flying from Knoxville to Medford

Discover the top airline that operate flights from Knoxville to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$462Average$827FlexibilityNo cancel feeOn-time69%

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