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Medford

$328+ Cheap flights from Knoxville to Medford (TYS - MFR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MFR
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from Knoxville to Medford

Cheapest flights from Knoxville to Medford
Explore the most affordable flight options available from Knoxville to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This Delta deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:24 pm
TYS
-
MFR
2 stops9h 28m
Delta
Fri 5/85:21 pm
MFR
-
TYS
2 stops12h 50m
Delta
Deal found 1/24$401
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:02 am
TYS
-
MFR
2 stops15h 28m
Delta
Wed 5/135:21 pm
MFR
-
TYS
2 stops12h 50m
Delta
Deal found 1/26$413
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:45 am
TYS
-
MFR
1 stop7h 24m
United Airlines
Thu 8/2012:45 pm
MFR
-
TYS
1 stop6h 35m
United Airlines
Deal found 1/24$423
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:00 am
TYS
-
MFR
2 stops13h 55m
United Airlines
Mon 5/46:36 pm
MFR
-
TYS
2 stops12h 30m
United Airlines
Deal found 1/24$501
This Delta deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:15 pm
TYS
-
MFR
2 stops8h 26m
Delta
Thu 8/205:55 am
MFR
-
TYS
2 stops12h 51m
Delta
Deal found 1/24$509

Find flight deals from Knoxville to Medford

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$401
(Delta)

One-way from

$328
(United Airlines)

Popular in

December

Cheapest in

May
Provider with most accurate pricing for Knoxville McGhee Tyson-Medford flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Medford flights.
Search Deals
From Knoxville McGhee Tyson to Medford
Search Deals
One-way flight from Knoxville McGhee Tyson to Medford
Search Deals
Highest demand for flights based on searches. 33% potential increase in price ($410 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($59 potential savings vs. average RT price).
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Knoxville

Fly to

Medford

Route

Depart

Return

Price

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

5:24 pm-11:52 pm

2 stops9h 28m

Medford

Fri 5/8

5:21 pm-9:11 am

2 stops12h 50m

$401

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 5/5

11:02 am-11:30 pm

2 stops15h 28m

Medford

Wed 5/13

5:21 pm-9:11 am

2 stops12h 50m

$413

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Thu 4/30

7:00 am-5:55 pm

2 stops13h 55m

Medford

Mon 5/4

6:36 pm-10:06 am

2 stops12h 30m

$501

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Tue 5/5

4:20 pm-9:31 pm

1 stop8h 11m

Medford

Wed 5/13

5:00 am-10:23 pm

1 stop14h 23m

$574

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

9:40 am-11:47 am

2 stops29h 07m

Medford

Fri 5/8

5:00 am-10:23 pm

1 stop14h 23m

$577

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 2/14

10:55 am-10:28 pm

2 stops14h 33m

$328

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 2/13

5:27 pm-9:18 pm

2 stops30h 51m

$368

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 2/14

5:35 am-2:36 pm

2 stops12h 01m

$428

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 2/13

6:35 am-4:40 pm

2 stops13h 05m

$462

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Compare providers for flights from Knoxville to Medford

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Medford in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Medford flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Medford flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Medford flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Medford flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Medford flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Medford

Have a flexible travel schedule? Discover the best time to fly to Medford from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Medford

What is the cheapest month to book a flight from Knoxville to Medford?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Medford (average of $216). Flying from Knoxville to Medford in July is currently the most expensive (average of $633). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Medford

Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated January 26, 2026.
Read reviews from past customers who have flown United Airlines from Knoxville to Medford. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,199 reviews

Crew

8.1

Comfort

7.3

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,199 reviews
United Airlines
7.4
Good
9,199 reviews

Crew

8.1

Comfort

7.3

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Medford?

    Airlines like Delta and United Airlines fly from Knoxville to Medford in about 9h 28m. The time it takes to get you to your destination can typically vary by up to 4h 27m. The distance from Knoxville to Medford is about 2113 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Knoxville to Medford round-trip?

    Cheapflights users have booked flights from Knoxville to Medford round-trip from $354. This flight start at 55% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Medford that include hotel bookings?

    Yes. In addition to deals on Knoxville to Medford flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Medford?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Medford.

  • Can I find deals for business class flights from Knoxville to Medford?

    Yes. Cheapflights offers flight deals from Knoxville to Medford by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Medford?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Medford (average of $216). Flying from Knoxville to Medford in July is currently the most expensive (average of $633). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
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Top airline flying from Knoxville to Medford

Discover the top airline that operate flights from Knoxville to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$354Average$823FlexibilityNo cancel feeOn-time69%

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