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Medford

$552+ Cheap flights from Knoxville to Medford (TYS - MFR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MFR
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Knoxville to Medford

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$552
(United Airlines)

Popular in

June

Cheapest in

March

Average price

$637
From Knoxville McGhee Tyson to Medford
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($188 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($59 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Knoxville to Medford

Cheapest flights from Knoxville to Medford
Explore the most affordable flight options available from Knoxville to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/44:40 pmTYS - MFR
1 stop7h 26mUnited Airlines
Sat 10/112:13 pmMFR - TYS
2 stops20h 12mUnited Airlines
Deal found 9/10$661

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Knoxville

Fly to

Medford

Route

Depart

Return

Price

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 3/6

4:25 pm-9:10 pm

1 stop7h 45m

Medford

Tue 3/10

5:10 am-2:39 pm

1 stop6h 29m

$552

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 10/4

4:40 pm-9:06 pm

1 stop7h 26m

Medford

Sat 10/11

2:13 pm-1:25 pm

2 stops20h 12m

$661

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Knoxville to Medford

Have a flexible travel schedule? Discover the best time to fly to Medford from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Medford

What is the cheapest month to book a flight from Knoxville to Medford?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Medford (average of $349). Flying from Knoxville to Medford in June is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MFR?

Find hourly flight availability from Knoxville to Medford. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Knoxville to Medford, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 35% versus a flight in the morning.

Reviews of airlines servicing Medford

Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown United Airlines from Knoxville to Medford. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Medford?

    Airlines like United Airlines fly from Knoxville to Medford in about 7h 45m. The time it takes to get you to your destination can typically vary by up to . The distance from Knoxville to Medford is about 2113 mi.

  • What is the cheapest airline to fly from Knoxville to Medford round-trip?

    Cheapflights users have booked flights from Knoxville to Medford round-trip from $453. This flight start at 31% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Medford that include hotel bookings?

    Yes. In addition to deals on Knoxville to Medford flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Medford?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Medford.

  • Can I find deals for business class flights from Knoxville to Medford?

    Yes. Cheapflights offers flight deals from Knoxville to Medford by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Medford?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Medford (average of $349). Flying from Knoxville to Medford in June is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Grants Pass
Yreka

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Top airline flying from Knoxville to Medford

Discover the top airline that operate flights from Knoxville to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$453Average$626FlexibilityNo cancel feeOn-time69%

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