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$353+ Cheap flights from Knoxville to Medford (TYS - MFR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MFR
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheap flight deals from Knoxville to Medford

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$569
(Delta)

One-way from

$394
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$684
Provider with most accurate pricing for Knoxville McGhee Tyson-Medford flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Medford flights.
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From Knoxville McGhee Tyson to Medford
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One-way flight from Knoxville McGhee Tyson to Medford
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Highest demand for flights based on searches. 19% potential increase in price ($167 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($63 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Knoxville to Medford

Cheapest flights from Knoxville to Medford
Explore the most affordable flight options available from Knoxville to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/314:58 pmTYS - MFR
1 stop7h 16mUnited Airlines
Wed 11/125:00 amMFR - TYS
1 stop6h 43mUnited Airlines
Deal found 10/26$353
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/314:58 pmTYS - MFR
1 stop7h 16mUnited Airlines
Wed 11/55:00 amMFR - TYS
1 stop6h 43mUnited Airlines
Deal found 10/28$401
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/48:26 amTYS - MFR
2 stops12h 26mUnited Airlines
Wed 11/125:00 amMFR - TYS
1 stop6h 43mUnited Airlines
Deal found 10/26$422
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/48:26 amTYS - MFR
2 stops12h 26mUnited Airlines
Sat 11/86:00 amMFR - TYS
2 stops14h 59mUnited Airlines
Deal found 10/26$475

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Knoxville

Fly to

Medford

Route

Depart

Return

Price

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 3/6

7:30 am-11:09 pm

2 stops18h 39m

Medford

Tue 3/10

5:21 pm-9:13 am

2 stops12h 52m

$569

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 3/6

4:25 pm-9:23 pm

1 stop7h 58m

Medford

Tue 3/10

5:10 am-8:54 pm

2 stops12h 44m

$705

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 12/3

4:30 pm-9:29 pm

1 stop7h 59m

Medford

Tue 12/9

5:00 am-3:07 pm

1 stop7h 07m

$1,347

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 12/3

7:10 am-4:43 pm

2 stops12h 33m

Medford

Tue 12/9

5:23 pm-9:38 am

2 stops13h 15m

$1,419

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 2/21

8:00 am-10:35 am

2 stops29h 35m

$394

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 2/21

8:45 am-9:18 pm

1 stop15h 33m

$717

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Compare providers for flights from Knoxville to Medford

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Medford in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Medford flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Medford flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Medford flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Medford flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Medford flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Medford

Have a flexible travel schedule? Discover the best time to fly to Medford from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Medford

What is the cheapest month to book a flight from Knoxville to Medford?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Medford (average of $216). Flying from Knoxville to Medford in July is currently the most expensive (average of $633). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Medford

Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated October 28, 2025.
Read reviews from past customers who have flown United Airlines from Knoxville to Medford. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,001 reviews

Overall

7.4

Food

6.6

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,001 reviews
United Airlines
7.4
Good
9,001 reviews

Overall

7.4

Food

6.6

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Medford?

    Airlines like Delta and United Airlines fly from Knoxville to Medford in about 7h 58m. The time it takes to get you to your destination can typically vary by up to 10h 41m. The distance from Knoxville to Medford is about 2113 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Knoxville to Medford round-trip?

    Cheapflights users have booked flights from Knoxville to Medford round-trip from $462. This flight start at 32% lower than the current average price 3 months from now.

  • Can I find deals for flights from Knoxville to Medford that include hotel bookings?

    Yes. In addition to deals on Knoxville to Medford flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Medford?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Medford.

  • Can I find deals for business class flights from Knoxville to Medford?

    Yes. Cheapflights offers flight deals from Knoxville to Medford by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Medford?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Medford (average of $216). Flying from Knoxville to Medford in July is currently the most expensive (average of $633). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Medford?

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Top airline flying from Knoxville to Medford

Discover the top airline that operate flights from Knoxville to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$462Average$762FlexibilityNo cancel feeOn-time69%

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