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Medford

$363+ Cheap flights from Knoxville to Medford (TYS - MFR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MFR
Apr 11 — Apr 181
Sat 4/11
Sat 4/18
1 adult, Economy
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Cheap flight deals from Knoxville to Medford

Cheapest flights from Knoxville to Medford
Explore the most affordable flight options available from Knoxville to Medford. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.

This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:30 pm
TYS
-
MFR
1 stop8h 07m
United Airlines
Fri 5/16:36 pm
MFR
-
TYS
2 stops13h 13m
United Airlines
Deal found 3/10$368
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:20 pm
TYS
-
MFR
1 stop8h 11m
United Airlines
Tue 5/56:00 am
MFR
-
TYS
2 stops13h 23m
United Airlines
Deal found 3/8$369
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:24 pm
TYS
-
MFR
2 stops9h 28m
Delta
Fri 5/85:25 pm
MFR
-
TYS
2 stops14h 46m
Delta
Deal found 3/7$420
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/48:30 am
TYS
-
MFR
1 stop7h 46m
United Airlines
Fri 4/106:31 pm
MFR
-
TYS
2 stops13h 19m
United Airlines
Deal found 3/10$432
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:56 pm
TYS
-
MFR
1 stop7h 20m
United Airlines
Thu 8/201:08 pm
MFR
-
TYS
1 stop6h 30m
United Airlines
Deal found 3/9$443
This Alaska Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2412:35 pm
TYS
-
MFR
2 stops13h 20m
Alaska Airlines
Wed 10/286:00 am
MFR
-
TYS
2 stops12h 45m
Alaska Airlines
Deal found 3/9$459

Find flight deals from Knoxville to Medford

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Medford (MFR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$368
(United Airlines)

One-way from

$363
(United Airlines)
Provider with most accurate pricing for Knoxville McGhee Tyson-Medford flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Medford flights.
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From Knoxville McGhee Tyson to Medford
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One-way flight from Knoxville McGhee Tyson to Medford
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Medford that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Knoxville to Medford that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 5/2

4:20 pm-9:31 pm

1 stop8h 11m

Medford

Tue 5/5

5:00 am-3:07 pm

1 stop7h 07m

$380

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

5:24 pm-11:52 pm

2 stops9h 28m

Medford

Fri 5/8

5:25 pm-11:11 am

2 stops14h 46m

$420

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 4/4

8:30 am-1:16 pm

1 stop7h 46m

Medford

Fri 4/10

12:50 pm-10:29 pm

1 stop6h 39m

$438
Quickest round-trip

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

4:56 pm-9:16 pm

1 stop7h 20m

Medford

Thu 8/20

1:08 pm-10:38 pm

1 stop6h 30m

$443

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Wed 8/12

6:15 pm-11:41 pm

2 stops8h 26m

Medford

Thu 8/20

5:21 pm-10:10 am

2 stops13h 49m

$464
Cheapest one-way
Quickest one-way

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Sat 5/2

9:12 am-1:01 pm

1 stop6h 49m

$363

KnoxvilleMedford

TYS - MFR

TYSMFR

Knoxville McGhee Tyson

Fri 5/1

4:20 pm-9:31 pm

1 stop8h 11m

$554

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/8

Sorted by cheapest first

Compare providers for flights from Knoxville to Medford

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Medford in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Medford flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Medford flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Medford flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Medford flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Medford flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Medford

Have a flexible travel schedule? Discover the best time to fly to Medford from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Medford

Get insights into the airlines that provide service to Medford. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medford. Reviews last updated March 12, 2026.
Read reviews from past customers who have flown United Airlines from Knoxville to Medford. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,418 reviews

Comfort

7.3

Boarding

7.7

Crew

8.1

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,418 reviews
United Airlines
7.4
Good
9,418 reviews

Comfort

7.3

Boarding

7.7

Crew

8.1

Overall

7.4

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Medford. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Medford?

    Airlines like United Airlines and Delta fly from Knoxville to Medford in about 8h 11m. The time it takes to get you to your destination can typically vary by up to 1h 17m. The distance from Knoxville to Medford is about 2113 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Knoxville to Medford round-trip?

    Cheapflights users have booked flights from Knoxville to Medford round-trip from $323.

  • Can I find deals for flights from Knoxville to Medford that include hotel bookings?

    Yes. In addition to deals on Knoxville to Medford flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Medford?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Medford.

  • Can I find deals for business class flights from Knoxville to Medford?

    Yes. Cheapflights offers flight deals from Knoxville to Medford by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
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Top airline flying from Knoxville to Medford

Discover the top airline that operate flights from Knoxville to Medford. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$323Average$733FlexibilityNo cancel feeOn-time69%

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