HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Louisville

$79+ Cheap flights from South Carolina to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDF
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Louisville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Louisville

Keep the following information in mind while searching for South Carolina to Louisville flight deals. Data was last updated September 17, 2025.

Round-trip from

$105
(Kiwi.com)

One-way from

$79
(Cheapflightsfares)

Popular in

March

Cheapest in

May

Average price

$360

Good round-trip deal

$107 or less

Good one-way deal

$74 or less
From South Carolina to Louisville Intl
Search Deals
One-way flight from South Carolina to Louisville Intl
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals
Price to beat on a round-trip flight from South Carolina to Louisville Intl.
Search Deals
Price to beat on a one-way flight from South Carolina to Louisville Intl.
Search Deals

Find flight deals from South Carolina to Louisville

Cheapest flights from South Carolina to Louisville
Explore the most affordable flight options available from South Carolina to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Mon 11/108:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 9/17$105
This Breeze Airways deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Mon 11/178:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 9/17$114
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:00 amMYR - SDF
1 stop10h 55mSpirit Airlines
Fri 10/317:15 amSDF - MYR
1 stop10h 29mSpirit Airlines
Deal found 9/17$124
This Breeze Airways deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Mon 10/208:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 9/15$144
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:40 pmCHS - SDF
1 stop16h 19mMultiple Airlines
Mon 11/108:52 pmSDF - CHS
Nonstop1h 36mMultiple Airlines
Deal found 9/17$145
This Breeze Airways deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/107:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Mon 10/138:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 9/15$164
This Breeze Airways deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Fri 12/58:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 9/17$166
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:05 amCHS - SDF
Nonstop1h 53mMultiple Airlines
Sun 10/196:58 pmSDF - CHS
1 stop14h 08mMultiple Airlines
Deal found 9/17$175
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1610:11 amCHS - SDF
1 stop22h 50mMultiple Airlines
Thu 10/236:58 pmSDF - CHS
1 stop14h 08mMultiple Airlines
Deal found 9/16$181
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:05 amCHS - SDF
Nonstop1h 53mMultiple Airlines
Mon 10/207:15 amSDF - CHS
1 stop25h 22mMultiple Airlines
Deal found 9/15$199
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:55 pmCLT - SDF
1 stop12h 40mMultiple Airlines
Mon 10/611:47 amSDF - CLT
1 stop9h 12mMultiple Airlines
Deal found 9/15$199
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:46 pmHHH - SDF
1 stop3h 35mAmerican Airlines
Thu 1/18:00 amSDF - HHH
1 stop6h 16mAmerican Airlines
Deal found 9/17$199

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from South Carolina to Louisville that are best for you.

Fly from

South Carolina

Fly to

Louisville

Route

Depart

Return

Price

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 11/7

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Mon 11/10

8:52 pm-10:28 pm

Nonstop1h 36m

$105

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Mon 11/10

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Mon 11/17

8:52 pm-10:28 pm

Nonstop1h 36m

$114

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Wed 10/29

7:00 am-5:55 pm

1 stop10h 55m

Louisville Intl

Fri 10/31

7:15 am-5:44 pm

1 stop10h 29m

$124

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 10/17

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Mon 10/20

8:52 pm-10:28 pm

Nonstop1h 36m

$144

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 10/10

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Mon 10/13

8:52 pm-10:28 pm

Nonstop1h 36m

$164

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Mon 12/1

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Fri 12/5

8:52 pm-10:28 pm

Nonstop1h 36m

$166

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 10/17

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Sun 10/19

6:58 pm-9:06 am

1 stop14h 08m

$175

Hilton Head IslandLouisville

HHH - SDF

HHHSDF

Hilton Head Island

Thu 12/25

2:46 pm-6:21 pm

1 stop3h 35m

Louisville Intl

Thu 1/1

8:00 am-2:16 pm

1 stop6h 16m

$199

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Tue 9/30

2:59 pm-9:19 am

1 stop18h 20m

Louisville Intl

Fri 10/3

8:52 pm-10:28 pm

Nonstop1h 36m

$202

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Thu 10/16

10:11 am-10:47 pm

2 stops12h 36m

Louisville Intl

Thu 10/23

6:58 pm-9:06 am

1 stop14h 08m

$218

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Louisville

What is the cheapest month to book a flight from South Carolina to Louisville?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $299). Flying from South Carolina to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SDF?

Find hourly flight availability from South Carolina to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from South Carolina to Louisville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from South Carolina?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from South Carolina to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How popular is this South Carolina to Louisville flight route?

    Within the past month, 1 users have taken a look at flights from South Carolina to Louisville Intl.

  • How long is the flight from South Carolina to Louisville?

    A quick flight from South Carolina to Louisville can take about 1h 53m. Breeze Airways provides one of the quickest options available for as low as $105. The distance between South Carolina and Louisville is about 485 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Louisville one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $79. Users have also found prices from $84 and $99 on Breeze Airways and Southwest, respectively.

  • What are the most popular routes from South Carolina to Louisville?

    Most travelers choose Charlotte Douglas - Louisville Intl, Columbia Metropolitan - Louisville Intl or Greenville - Louisville Intl when deciding on the best route from South Carolina to Louisville.

  • What are the cheapest flights from South Carolina to Louisville?

    The cheapest flight price from South Carolina to Louisville is $55. On average you can expect to pay $140. The most popular route, (Charlotte Douglas - Louisville Intl), can usually be booked for $212.

  • Can I find deals for flights from South Carolina to Louisville that include hotel bookings?

    Yes. In addition to deals on South Carolina to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Louisville.

  • Can I find deals for business class flights from South Carolina to Louisville?

    Yes. Cheapflights offers flight deals from South Carolina to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Louisville?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $299). Flying from South Carolina to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Nashville flights
Newark to Nashville flights
LaGuardia to Nashville flights
Boston to Nashville flights
Seattle to Nashville flights
Los Angeles to Nashville flights
John F Kennedy Intl to Cincinnati flights
LaGuardia to Cincinnati flights
San Francisco to Nashville flights
Reagan-National to Nashville flights
Dallas/Fort Worth to Nashville flights
O'Hare Intl to Nashville flights
Boston to Cincinnati flights
Philadelphia to Nashville flights
Denver to Nashville flights
Raleigh to Nashville flights
Dulles Intl to Nashville flights
Newark to Cincinnati flights
Hobby to Nashville flights
Providence to Nashville flights
Ontario to Nashville flights
Minneapolis to Nashville flights
Baltimore to Nashville flights
Dallas/Fort Worth to Cincinnati flights
Fort Lauderdale to Nashville flights
George Bush Intcntl to Nashville flights
Portland to Nashville flights
Sky Harbor Intl to Nashville flights
LaGuardia to Louisville flights
Newark to Louisville flights
O'Hare Intl to Knoxville flights
Santa Ana to Nashville flights
LaGuardia to Knoxville flights
Detroit to Nashville flights
Hartford to Nashville flights
Dallas/Fort Worth to Louisville flights
Boston to Louisville flights
Denver to Cincinnati flights
Seattle to Cincinnati flights
Tampa to Nashville flights
Dallas/Fort Worth to Knoxville flights
O'Hare Intl to Cincinnati flights
Miami to Nashville flights
Cleveland to Nashville flights
John F Kennedy Intl to Louisville flights
Salt Lake City to Nashville flights
Orlando to Nashville flights
Burbank to Nashville flights
Reagan-National to Knoxville flights
John F Kennedy Intl to Knoxville flights

Top 5 airlines flying from South Carolina to Louisville

Discover the top 5 airlines that operate flights from South Carolina to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$31Average$133FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$51Average$162FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$176Average$378FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$338FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$348FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.