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$60+ Cheap flights from South Carolina to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDF
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from South Carolina to Louisville

Cheapest flights from South Carolina to Louisville
Explore the most affordable flight options available from South Carolina to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:07 amCAE - SDF
1 stop3h 43mAmerican Airlines
Mon 12/297:24 pmSDF - CAE
1 stop4h 43mAmerican Airlines
Deal found 12/25$319
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:05 pmCLT - SDF
1 stop6h 53mDelta
Thu 1/17:25 amSDF - CLT
1 stop5h 00mDelta
Deal found 12/27$373
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amCLT - SDF
1 stop3h 29mDelta
Sat 1/36:00 amSDF - CLT
1 stop4h 53mDelta
Deal found 12/27$421
This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:54 pmCLT - SDF
1 stop4h 17mUnited Airlines
Thu 1/12:00 pmSDF - CLT
2 stops9h 59mUnited Airlines
Deal found 12/27$438
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:08 pmCHS - SDF
2 stops17h 07mMultiple Airlines
Sun 1/45:05 amSDF - CHS
1 stop16h 18mMultiple Airlines
Deal found 12/26$439
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:05 pmCLT - SDF
1 stop6h 53mDelta
Fri 1/24:44 pmSDF - CLT
1 stop3h 35mDelta
Deal found 12/27$453
This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amCLT - SDF
1 stop8h 03mUnited Airlines
Sat 1/35:40 amSDF - CLT
2 stops8h 31mUnited Airlines
Deal found 12/27$456
This Southwest deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:05 pmCLT - SDF
1 stop4h 25mSouthwest
Sat 1/37:05 amSDF - CLT
1 stop5h 05mSouthwest
Deal found 12/27$459
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:40 pmCLT - SDF
Nonstop1h 34mAmerican Airlines
Fri 1/29:20 amSDF - CLT
Nonstop1h 45mAmerican Airlines
Deal found 12/28$463
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amCLT - SDF
1 stop7h 12mDelta
Wed 12/314:49 pmSDF - CLT
1 stop3h 30mDelta
Deal found 12/27$469
This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amCLT - SDF
2 stops7h 13mUnited Airlines
Sat 1/39:55 amSDF - CLT
1 stop4h 16mUnited Airlines
Deal found 12/27$474
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:08 pmCHS - SDF
1 stop22h 15mMultiple Airlines
Thu 1/12:55 pmSDF - CHS
2 stops8h 04mMultiple Airlines
Deal found 12/26$529

Find flight deals from South Carolina to Louisville

Keep the following information in mind while searching for South Carolina to Louisville flight deals. Data was last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$179
(Kiwi.com)

One-way from

$60
(Kiwi.com)

Popular in

March

Cheapest in

May

Average price

$410

Good round-trip deal

$277 or less
Provider with most accurate pricing for Myrtle Beach Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Louisville Intl flights.
Search Deals
From South Carolina to Louisville Intl
Search Deals
One-way flight from South Carolina to Louisville Intl
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($99 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from South Carolina to Louisville Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from South Carolina to Louisville that are best for you.

Fly from

South Carolina

Fly to

Louisville

Route

Depart

Return

Price

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Mon 1/26

5:24 pm-2:41 pm

1 stop21h 17m

Louisville Intl

Mon 2/2

1:55 pm-10:40 am

1 stop20h 45m

$182

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Mon 2/2

6:35 pm-2:41 pm

1 stop20h 06m

Louisville Intl

Mon 2/9

1:55 pm-8:38 am

1 stop18h 43m

$193

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Mon 2/9

5:24 pm-2:41 pm

1 stop21h 17m

Louisville Intl

Mon 2/16

1:19 pm-10:17 am

1 stop20h 58m

$204

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Tue 2/24

6:01 pm-12:21 pm

1 stop18h 20m

Louisville Intl

Mon 3/2

1:19 pm-10:17 am

1 stop20h 58m

$217

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Tue 2/24

6:01 pm-12:21 pm

1 stop18h 20m

Louisville Intl

Fri 2/27

1:19 pm-2:17 pm

2 stops24h 58m

$219

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Fri 2/27

6:47 pm-11:05 am

1 stop16h 18m

Louisville Intl

Mon 3/2

9:30 am-8:26 am

1 stop22h 56m

$219

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Mon 2/2

5:24 pm-2:41 pm

1 stop21h 17m

Louisville Intl

Fri 2/6

1:55 pm-12:40 am

2 stops10h 45m

$223

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Wed 2/18

9:09 am-2:38 pm

1 stop29h 29m

Louisville Intl

Mon 2/23

9:30 am-8:13 am

1 stop22h 43m

$226

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Thu 2/19

11:00 am-8:40 am

1 stop21h 40m

Louisville Intl

Sun 2/22

3:33 pm-11:56 pm

1 stop8h 23m

$226

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Fri 2/27

6:47 pm-11:05 am

1 stop16h 18m

Louisville Intl

Sun 3/1

3:33 pm-11:56 pm

1 stop8h 23m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Louisville

What is the cheapest month to book a flight from South Carolina to Louisville?

Currently, May is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $31). Flying from South Carolina to Louisville in January is currently the most expensive (average of $98). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SDF?

Find hourly flight availability from South Carolina to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 28, 2025.

It’s optimal to fly from South Carolina to Louisville at noon. By choosing this option you can save up to 69% on the cost of your flight, compared to a flight in the evening.

How much does it cost to fly round-trip from South Carolina to Louisville?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from South Carolina?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from South Carolina to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How popular is this South Carolina to Louisville flight route?

    Within the past month, 1 users have taken a look at flights from South Carolina to Louisville Intl.

  • How long is the flight from South Carolina to Louisville?

    A quick flight from South Carolina to Louisville can take about 5h 07m. Spirit Airlines provides one of the quickest options available for as low as $239. The distance between South Carolina and Louisville is about 485 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Louisville?

    Most travelers choose Charlotte Douglas - Louisville Intl, Savannah/Hilton Head - Louisville Intl or Charleston - Louisville Intl when deciding on the best route from South Carolina to Louisville.

  • What are the cheapest flights from South Carolina to Louisville?

    The cheapest flight price from South Carolina to Louisville is $78. On average you can expect to pay $292. The most popular route, (Charlotte Douglas - Louisville Intl), can usually be booked for $182.

  • Can I find deals for flights from South Carolina to Louisville that include hotel bookings?

    Yes. In addition to deals on South Carolina to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Louisville.

  • Can I find deals for business class flights from South Carolina to Louisville?

    Yes. Cheapflights offers flight deals from South Carolina to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Louisville?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $31). Flying from South Carolina to Louisville in January is currently the most expensive (average of $98). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 3 airlines flying from South Carolina to Louisville

Discover the top 3 airlines that operate flights from South Carolina to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$51Average$144FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$176Average$378FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$321FlexibilityNo cancel feeOn-time71%

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