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$89+ Cheap flights from South Carolina to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDF
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from South Carolina to Louisville

Keep the following information in mind while searching for South Carolina to Louisville flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$93
(Breeze Airways)

One-way from

$89
(Kiwi.com)

Popular in

March

Cheapest in

May

Average price

$333

Good round-trip deal

$99 or less

Good one-way deal

$104 or less
Provider with most accurate pricing for Myrtle Beach Intl-Louisville Intl flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Louisville Intl flights.
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From South Carolina to Louisville Intl
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One-way flight from South Carolina to Louisville Intl
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Highest demand for flights based on searches. 25% potential increase in price ($109 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($31 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from South Carolina to Louisville Intl.
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Price to beat on a one-way flight from South Carolina to Louisville Intl.
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Find flight deals from South Carolina to Louisville

Cheapest flights from South Carolina to Louisville
Explore the most affordable flight options available from South Carolina to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Breeze Airways deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Mon 12/158:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 11/2$93
This Breeze Airways deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Mon 11/178:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 11/2$119
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/177:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Fri 11/218:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 11/3$128
This Priceline deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:05 amCHS - SDF
Nonstop1h 53mMultiple Airlines
Mon 12/1511:55 amSDF - CHS
1 stop8h 59mMultiple Airlines
Deal found 11/2$137
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:44 pmCLT - SDF
1 stop23h 32mMultiple Airlines
Sun 11/168:53 pmSDF - CLT
1 stop12h 09mMultiple Airlines
Deal found 11/2$203
This Expedia deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/177:00 amCHS - SDF
1 stop11h 16mMultiple Airlines
Fri 11/218:52 pmSDF - CHS
Nonstop1h 36mMultiple Airlines
Deal found 11/3$205
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:57 pmCLT - SDF
1 stop20h 03mMultiple Airlines
Sun 12/79:26 pmSDF - CLT
1 stop12h 11mMultiple Airlines
Deal found 11/3$224
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:46 pmHHH - SDF
1 stop3h 35mAmerican Airlines
Fri 1/28:00 amSDF - HHH
1 stop6h 16mAmerican Airlines
Deal found 11/2$224
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:34 amCAE - SDF
1 stop6h 39mDelta
Sun 12/76:00 amSDF - CAE
1 stop6h 08mDelta
Deal found 11/2$229
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Sun 11/168:05 pmSDF - CHS
1 stop11h 29mBreeze Airways
Deal found 11/3$248
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:05 amCHS - SDF
Nonstop1h 53mBreeze Airways
Mon 12/298:52 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 11/3$250
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:30 pmSAV - SDF
1 stop8h 19mMultiple Airlines
Mon 1/55:05 amSDF - SAV
1 stop16h 39mMultiple Airlines
Deal found 11/3$250

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from South Carolina to Louisville that are best for you.

Fly from

South Carolina

Fly to

Louisville

Route

Depart

Return

Price

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 12/12

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Mon 12/15

8:52 pm-10:28 pm

Nonstop1h 36m

$93

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Mon 11/17

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Fri 11/21

8:52 pm-10:28 pm

Nonstop1h 36m

$128

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 12/12

7:05 am-8:58 am

Nonstop1h 53m

Louisville Intl

Mon 12/15

11:55 am-8:54 pm

1 stop8h 59m

$137

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Mon 11/17

7:00 am-6:16 pm

1 stop11h 16m

Louisville Intl

Fri 11/21

8:52 pm-10:28 pm

Nonstop1h 36m

$205

Hilton Head IslandLouisville

HHH - SDF

HHHSDF

Hilton Head Island

Thu 12/25

2:46 pm-6:21 pm

1 stop3h 35m

Louisville Intl

Fri 1/2

8:00 am-2:16 pm

1 stop6h 16m

$224

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Sat 12/6

2:57 pm-11:00 am

1 stop20h 03m

Louisville Intl

Sun 12/7

9:26 pm-9:37 am

1 stop12h 11m

$224

ColumbiaLouisville

CAE - SDF

CAESDF

Columbia Metropolitan

Thu 1/8

5:35 am-9:28 am

1 stop3h 53m

Louisville Intl

Sun 1/11

6:00 am-9:30 am

1 stop3h 30m

$229

ColumbiaLouisville

CAE - SDF

CAESDF

Columbia Metropolitan

Sat 2/21

8:45 am-1:50 pm

1 stop5h 05m

Louisville Intl

Tue 2/24

12:40 pm-4:29 pm

1 stop3h 49m

$229

ColumbiaLouisville

CAE - SDF

CAESDF

Columbia Metropolitan

Thu 12/4

5:34 am-12:13 pm

1 stop6h 39m

Louisville Intl

Sun 12/7

6:00 am-12:08 pm

1 stop6h 08m

$229

ColumbiaLouisville

CAE - SDF

CAESDF

Columbia Metropolitan

Thu 1/8

10:10 am-6:39 pm

2 stops8h 29m

Louisville Intl

Sun 1/11

6:00 am-9:42 am

1 stop3h 42m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Louisville

What is the cheapest month to book a flight from South Carolina to Louisville?

Currently, May is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $31). Flying from South Carolina to Louisville in January is currently the most expensive (average of $107). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SDF?

Find hourly flight availability from South Carolina to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

It’s optimal to fly from South Carolina to Louisville in the afternoon. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from South Carolina to Louisville?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Louisville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Louisville flight should consider departing on Saturday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from South Carolina?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from South Carolina to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How popular is this South Carolina to Louisville flight route?

    Within the past month, 1 users have taken a look at flights from South Carolina to Louisville Intl.

  • How long is the flight from South Carolina to Louisville?

    A quick flight from South Carolina to Louisville can take about 1h 53m. Breeze Airways provides one of the quickest options available for as low as $93. The distance between South Carolina and Louisville is about 485 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Louisville one-way?

    For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $95. Users have also found prices from $118 and $119 on American Airlines and Delta, respectively.

  • What are the most popular routes from South Carolina to Louisville?

    Most travelers choose Charlotte Douglas - Louisville Intl, Greenville - Louisville Intl or Savannah/Hilton Head - Louisville Intl when deciding on the best route from South Carolina to Louisville.

  • What are the cheapest flights from South Carolina to Louisville?

    The cheapest flight price from South Carolina to Louisville is $65. On average you can expect to pay $158. The most popular route, (Charlotte Douglas - Louisville Intl), can usually be booked for $281.

  • Can I find deals for flights from South Carolina to Louisville that include hotel bookings?

    Yes. In addition to deals on South Carolina to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Louisville.

  • Can I find deals for business class flights from South Carolina to Louisville?

    Yes. Cheapflights offers flight deals from South Carolina to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Louisville?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $31). Flying from South Carolina to Louisville in January is currently the most expensive (average of $107). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 4 airlines flying from South Carolina to Louisville

Discover the top 4 airlines that operate flights from South Carolina to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$31Average$133FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$51Average$159FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$176Average$372FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$331FlexibilityNo cancel feeOn-time71%

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