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$54+ Cheap flights from Denver to Knoxville (DEN - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
jul. 8 — jul. 151
mar. 7/8
mar. 7/15
1 adult, Economy
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Cheapflights Tip: The best prices from Denver Intl to Knoxville McGhee Tyson are usually found in August or September, booked 46 days in advance, depart on a Thursday or Sunday and return on a Thursday

Cheap flight deals from Denver to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 3, 2025.

Round-trip from

$110
(Gotogate)

One-way from

$54
(Booking.com)

Popular in

March

Cheapest in

August

Average price

$248

Good round-trip deal

$168 or less

Good one-way deal

$119 or less
From Denver Intl to Knoxville McGhee Tyson
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One-way flight from Denver Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 4% potential increase in price ($13 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Denver Intl to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Denver Intl to Knoxville McGhee Tyson.
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Find flight deals from Denver to Knoxville

Cheapest flights from Denver to Knoxville
Explore the most affordable flight options available from Denver to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 3, 2025.

This Gotogate deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/315:42 pmDEN - TYS
Nonstop2h 45mAllegiant Air
dom. 8/33:54 pmTYS - DEN
Nonstop3h 03mAllegiant Air
Deal found 7/1$110
This Priceline deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/112:55 pmDEN - TYS
Nonstop2h 46mFrontier
jue. 9/188:26 pmTYS - DEN
Nonstop3h 09mFrontier
Deal found 7/2$118
This Trip.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/118:15 amDEN - TYS
1 stop6h 57mMultiple Airlines
jue. 8/143:52 pmTYS - DEN
Nonstop3h 08mMultiple Airlines
Deal found 7/1$187
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/147:02 amDEN - TYS
1 stop8h 38mAmerican Airlines
lun. 8/1812:20 pmTYS - DEN
1 stop7h 27mAmerican Airlines
Deal found 7/2$219
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/1512:45 amDEN - TYS
1 stop7h 19mDelta
mié. 8/206:14 pmTYS - DEN
1 stop6h 41mDelta
Deal found 7/3$237
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/146:01 amDEN - TYS
1 stop6h 57mUnited Airlines
dom. 8/314:40 pmTYS - DEN
Nonstop3h 12mUnited Airlines
Deal found 7/2$274

Cheapflights Fare Finder

Customize your flight search to find flights from Denver to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
Use the filters below to find and compare flights from Denver to Knoxville that are best for you.

Fly from

Denver

Fly to

Knoxville

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

jue. 7/31

5:42 pm-10:27 pm

Nonstop2h 45m

Knoxville McGhee Tyson

dom. 8/3

3:54 pm-4:57 pm

Nonstop3h 03m

$110

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

jue. 9/11

2:55 pm-7:41 pm

Nonstop2h 46m

Knoxville McGhee Tyson

jue. 9/18

8:26 pm-9:35 pm

Nonstop3h 09m

$118

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

lun. 8/11

8:15 am-5:12 pm

1 stop6h 57m

Knoxville McGhee Tyson

jue. 8/14

3:52 pm-5:00 pm

Nonstop3h 08m

$187

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

jue. 8/14

7:02 am-5:40 pm

1 stop8h 38m

Knoxville McGhee Tyson

lun. 8/18

12:20 pm-5:47 pm

1 stop7h 27m

$219

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

vie. 8/15

12:45 am-10:04 am

1 stop7h 19m

Knoxville McGhee Tyson

mié. 8/20

6:14 pm-10:55 pm

1 stop6h 41m

$237

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

jue. 8/14

6:01 am-2:58 pm

1 stop6h 57m

Knoxville McGhee Tyson

dom. 8/31

4:40 pm-5:52 pm

Nonstop3h 12m

$274

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

jue. 10/23

8:54 am-1:33 pm

Nonstop2h 39m

$54

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

jue. 10/16

2:48 pm-7:37 pm

Nonstop2h 49m

$79

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

lun. 9/1

5:00 am-1:36 pm

1 stop6h 36m

$129

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

jue. 10/16

10:45 am-6:13 pm

1 stop5h 28m

$149

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 12 results
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Best time to book a flight from Denver to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Knoxville

How far ahead should I book a flight from Denver to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Knoxville. Price data was last updated on June 27, 2025.

The price you pay for your flight from Denver to Knoxville may vary depending on when you book. For the best chance of a lower fare, look to book 46 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Denver to Knoxville (average of $296). Flying from Denver to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to TYS?

Find hourly flight availability from Denver to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 3, 2025.

It’s typically best to fly out from Denver to Knoxville at noon. Doing so could potentially save you 47% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from Denver to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Denver to Knoxville. Price data was last updated on June 29, 2025.

Travelers seeking maximum savings on their Denver to Knoxville flight should consider departing on Wednesday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Denver to Knoxville

Explore weekly flight availability from Denver to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated julio 3, 2025.

The most flights from DEN to TYS are scheduled on a Thursday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated julio 3, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Denver to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,970 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,970 reviews
Delta
8.0
Very good
7,970 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,845 reviews
Delta
8.0
Very good
7,970 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,970 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Allegiant Air
7.2
Good
709 reviews
Delta
8.0
Very good
7,970 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.9
Fair
3,284 reviews
Delta
8.0
Very good
7,970 reviews

Comfort

7.9

Boarding

8.2

Entertainment

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Denver to Knoxville?

    Booking a flight from Denver Intl (DEN) to Knoxville McGhee Tyson (TYS) is your only option if you wish to fly from Denver to Knoxville. On a typical day, there are 2 flights from Denver Intl to McGhee Tyson, all of which are around 2h 39m for a nonstop flight. You can also purchase a plane ticket from 5 airlines when you book a flight from Denver Intl to Knoxville.

  • How popular is this Denver to Knoxville flight route?

    Within the past month, 1 users have taken a look at flights from Denver Intl to Knoxville McGhee Tyson.

  • What are the cheapest airlines flying from Denver to Knoxville round-trip?

    Our cheapest airline available from Denver to Knoxville is Allegiant Air. Our recent data shows that you can find tickets from as low as $110 on this airline. Additional options worth looking into are Frontier and American Airlines, starting at $118 and $219 round-trip. These flights start at 55% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Denver to Knoxville one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $54. Users have also found prices from $79 and $129 on Frontier and American Airlines, respectively.

  • What are the most reliable airlines from Denver to Knoxville?

    The top 3 most reliable airlines when flying from Denver to Knoxville are Frontier (83%), United Airlines (72%) and SkyWest Airlines (59%).

  • What are the cheapest flights from Denver to Knoxville?

    Looking for the cheapest flight from Denver to Knoxville? While on average our users pay $198, our data indicates the cheapest price to be $82. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $88.

  • Can I find deals for flights from Denver to Knoxville that include hotel bookings?

    Yes. In addition to deals on Denver to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Knoxville.

  • Can I find deals for business class flights from Denver to Knoxville?

    Yes. Cheapflights offers flight deals from Denver to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Denver to Knoxville (average of $296). Flying from Denver to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Denver?

Book flights to Denver if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Alternative routes for Denver to Knoxville

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Top 5 airlines flying from Denver to Knoxville

Discover the top 5 airlines that operate flights from Denver to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$59Average$147FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$68Average$129FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$208Average$301FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$233Average$453FlexibilityNo cancel feeOn-time69%
DeltaCheapest$243Average$293FlexibilityNo cancel feeOn-timeN/A

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