$1,259+ Cheap flights from Colorado to La Serena (LSC)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/20. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — LSC
Mar 9 — Mar 161
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Colorado to La SerenaExplore the most affordable flight options available from Colorado to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.
Explore the most affordable flight options available from Colorado to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.
This Priceline deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:51 pm
DEN
- LSC
2 stops44h 47m
LATAM Airlines
Fri 3/2710:25 pm
LSC
- DEN
2 stops48h 11m
LATAM Airlines
Deal found 2/3![LATAM Airlines logo]()
$1,259
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:29 pm
DEN
- LSC
3 stops25h 36m
Multiple Airlines
Fri 3/274:31 pm
LSC
- DEN
3 stops30h 24m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$1,363
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1212:29 pm
DEN
- LSC
3 stops25h 23m
Multiple Airlines
Mon 2/168:45 pm
LSC
- DEN
2 stops41h 38m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$1,856
This KAYAK deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/122:45 pm
DEN
- LSC
2 stops20h 20m
LATAM Airlines
Mon 2/168:45 pm
LSC
- DEN
2 stops16h 56m
LATAM Airlines
Deal found 2/3![LATAM Airlines logo]()
$2,072
Best flights from Colorado to La SerenaDiscover carefully curated flight deals from Colorado to La Serena that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 7, 2026.
Discover carefully curated flight deals from Colorado to La Serena that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 7, 2026.
This Priceline deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:51 pm
DEN
- LSC
2 stops44h 47m
LATAM Airlines
Fri 3/2710:25 pm
LSC
- DEN
2 stops48h 11m
LATAM Airlines
Deal found 2/3![LATAM Airlines logo]()
$1,259
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:29 pm
DEN
- LSC
3 stops25h 36m
Multiple Airlines
Fri 3/274:31 pm
LSC
- DEN
3 stops30h 24m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$1,363
Last-minute flights from Colorado to La SerenaDiscover last-minute flight deals from Colorado to La Serena. Data last updated February 7, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to La Serena. Data last updated February 7, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1212:29 pm
DEN
- LSC
3 stops25h 23m
Multiple Airlines
Mon 2/168:45 pm
LSC
- DEN
2 stops41h 38m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$1,856
This KAYAK deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/122:45 pm
DEN
- LSC
2 stops20h 20m
LATAM Airlines
Mon 2/168:45 pm
LSC
- DEN
2 stops16h 56m
LATAM Airlines
Deal found 2/3![LATAM Airlines logo]()
$2,072
This Priceline deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:51 pm
DEN
- LSC
2 stops44h 47m
LATAM Airlines
Fri 3/2710:25 pm
LSC
- DEN
2 stops48h 11m
LATAM Airlines
Deal found 2/3![LATAM Airlines logo]()
$1,259
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:29 pm
DEN
- LSC
3 stops25h 36m
Multiple Airlines
Fri 3/274:31 pm
LSC
- DEN
3 stops30h 24m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$1,363
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to La Serena that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Colorado to La Serena that are best for you.
Fly from
Colorado
Fly to
La Serena
Route
Depart
Return
Price
DenverLa Serena
DEN - LSC
DENLSC
Denver Intl
Fri 3/20
12:51 pm-12:38 pm
2 stops44h 47m
La Serena La Florida
Fri 3/27
10:25 pm-7:36 pm
2 stops48h 11m
$1,259
DenverLa Serena
DEN - LSC
DENLSC
Denver Intl
Fri 3/20
1:29 pm-6:05 pm
3 stops25h 36m
La Serena La Florida
Fri 3/27
4:31 pm-7:55 pm
3 stops30h 24m
$1,363
Best time to book a flight from Colorado to La Serena
Have a flexible travel schedule? Discover the best time to fly to La Serena from Colorado with our price prediction graph.
DEN-LSC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to La Serena
USCO-LSC
DEN-LSC
No data available for this route at this time. Please check back soon.
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