Santiago

$475+ Cheap flights from San Antonio (SAT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
May 29 — Jun 51
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Cheap flight deals from San Antonio to Santiago

Cheapest flights from San Antonio to Santiago
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:00 pm
SAT
-
SCL
1 stop17h 50m
American Airlines
Tue 10/69:30 pm
SCL
-
SAT
1 stop22h 12m
American Airlines
Deal found 4/28$875
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:04 pm
SAT
-
SCL
1 stop11h 46m
American Airlines
Tue 11/1010:15 pm
SCL
-
SAT
1 stop28h 42m
American Airlines
Deal found 4/27$887
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:16 pm
SAT
-
SCL
3 stops27h 19m
Multiple Airlines
Thu 7/233:20 pm
SCL
-
SAT
2 stops28h 17m
Multiple Airlines
Deal found 4/26$894
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:25 pm
SAT
-
SCL
1 stop13h 50m
Delta
Mon 10/58:40 pm
SCL
-
SAT
1 stop15h 14m
Delta
Deal found 4/28$915
This KAYAK deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:10 pm
SAT
-
SCL
3 stops21h 15m
LATAM Airlines
Tue 10/277:45 am
SCL
-
SAT
2 stops18h 43m
LATAM Airlines
Deal found 4/28$920
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:10 pm
SAT
-
SCL
1 stop35h 25m
Delta
Wed 10/77:15 am
SCL
-
SAT
2 stops19h 13m
Delta
Deal found 4/28$926
This Expedia deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:10 pm
SAT
-
SCL
1 stop16h 05m
LATAM Airlines
Tue 10/2712:10 am
SCL
-
SAT
1 stop13h 16m
LATAM Airlines
Deal found 4/28$936
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:45 am
SAT
-
SCL
2 stops20h 15m
Delta
Mon 11/3011:25 pm
SCL
-
SAT
1 stop26h 53m
Delta
Deal found 4/28$965
This KAYAK deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:25 pm
SAT
-
SCL
1 stop12h 15m
LATAM Airlines
Fri 11/2711:05 pm
SCL
-
SAT
2 stops21h 13m
LATAM Airlines
Deal found 4/28$970
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:10 pm
SAT
-
SCL
1 stop35h 25m
Delta
Sun 10/411:25 pm
SCL
-
SAT
1 stop17h 17m
Delta
Deal found 4/28$976

Find flight deals from San Antonio to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$875
(American Airlines)

One-way from

$475
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$1,429
Provider with most accurate pricing for San Antonio-Santiago Arturo Merino Benitez flight deals.
Provider most trusted by Cheapflights users for San Antonio-Santiago Arturo Merino Benitez flights.
From San Antonio to Santiago Arturo Merino Benitez
One-way flight from San Antonio to Santiago Arturo Merino Benitez
Highest demand for flights based on searches. 9% potential increase in price ($110 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($41 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Wed 10/21

11:03 am-7:50 am

2 stops18h 47m

Santiago Arturo Merino Benitez

Tue 11/10

10:15 pm-12:03 pm

2 stops16h 48m

$880

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 9/28

12:15 pm-8:15 am

1 stop18h 00m

Santiago Arturo Merino Benitez

Wed 10/7

11:25 pm-2:39 pm

1 stop17h 14m

$915

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Mon 9/28

6:45 am-8:15 am

1 stop23h 30m

Santiago Arturo Merino Benitez

Mon 10/5

7:15 am-12:15 am

2 stops19h 00m

$915

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 9/27

4:10 pm-5:35 am

1 stop35h 25m

Santiago Arturo Merino Benitez

Mon 10/5

7:45 pm-1:22 pm

2 stops19h 37m

$926

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sun 9/27

4:10 pm-5:35 am

1 stop35h 25m

Santiago Arturo Merino Benitez

Sun 10/4

7:45 pm-1:07 pm

2 stops19h 22m

$926

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Sat 8/15

2:10 pm-6:55 am

2 stops15h 45m

Santiago Arturo Merino Benitez

Sat 8/29

11:00 pm-8:10 pm

2 stops22h 10m

$1,023

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Fri 8/7

10:38 am-6:00 am

2 stops18h 22m

Santiago Arturo Merino Benitez

Sat 8/15

11:05 pm-8:10 pm

2 stops22h 05m

$1,057
Quickest round-trip

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Tue 6/9

10:51 am-7:05 am

2 stops19h 14m

Santiago Arturo Merino Benitez

Thu 7/23

9:00 pm-11:52 am

2 stops15h 52m

$1,065
Cheapest one-way

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 8/6

7:04 pm-3:25 am

3 stops31h 21m

$475
Quickest one-way

San AntonioSantiago

SAT - SCL

SATSCL

San Antonio

Thu 8/6

2:21 pm-7:15 am

1 stop15h 54m

$596

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Sorted by cheapest first

Compare providers for flights from San Antonio to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Santiago

How much does it cost to fly round-trip from San Antonio to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 29, 2026.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as LATAM Airlines,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.0

Crew

8.0

Food

6.7

Overall

7.4

Boarding

7.5

Comfort

7.3

Reviews

1 / 20
6.0
Good

Juan,Apr 2026

BOG - CLO

Very old aircraft and it was very dirty in the seats and floor

Entertainment

7.0

Crew

8.0

Food

6.7

Overall

7.4

Boarding

7.5

Comfort

7.3

Reviews

1 / 20
6.0
Good

Juan,Apr 2026

BOG - CLO

Very old aircraft and it was very dirty in the seats and floor

Entertainment

7.0

Crew

8.0

Food

6.7

Overall

7.4

Boarding

7.5

Comfort

7.3

Reviews

1 / 20
6.0
Good

Juan,Apr 2026

BOG - CLO

Very old aircraft and it was very dirty in the seats and floor

Entertainment

7.0

Crew

8.0

Food

6.7

Overall

7.4

Boarding

7.5

Comfort

7.3

Reviews

1 / 20
6.0
Good

Juan,Apr 2026

BOG - CLO

Very old aircraft and it was very dirty in the seats and floor

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from San Antonio to Santiago?

    A quick flight from San Antonio to Santiago can take about 13h 50m. American Airlines provides one of the quickest options available for as low as $915. San Antonio and Santiago are separated by a distance of 4706 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Antonio to Santiago round-trip?

    United Airlines, at $566, was found to be the cheapest airline from San Antonio to Santiago.Alternate airlines to your destination round-trip include LATAM Airlines and American Airlines. United Airlines is priced at 44% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Santiago that include hotel bookings?

    Yes. In addition to deals on San Antonio to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Santiago.

  • Can I find deals for business class flights from San Antonio to Santiago?

    Yes. Cheapflights offers flight deals from San Antonio to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for San Antonio to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from San Antonio to Santiago

Discover the top 3 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$566Average$875FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$738Average$1,098FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$783Average$1,139FlexibilityNo cancel feeOn-time71%

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