$354+ Cheap flights from San Antonio (SAT) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Find cheap flights from San Antonio to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Santiago
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Cheapest flights from San Antonio to SantiagoExplore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This Trip.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:05 am
SAT
- SCL
2 stops36h 15m
Multiple Airlines
Fri 9/187:40 am
SCL
- SAT
3 stops37h 45m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$699
This oojo deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:45 pm
SAT
- SCL
2 stops36h 10m
LATAM Airlines
Thu 8/278:30 am
SCL
- SAT
3 stops27h 40m
LATAM Airlines
Deal found 7/28![LATAM Airlines logo]()
$913
This oojo deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:30 am
SAT
- SCL
2 stops22h 10m
LATAM Airlines
Thu 9/175:10 am
SCL
- SAT
2 stops20h 58m
LATAM Airlines
Deal found 7/29![LATAM Airlines logo]()
$924
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:03 pm
SAT
- SCL
2 stops15h 57m
American Airlines
Thu 9/179:30 pm
SCL
- SAT
2 stops17h 37m
American Airlines
Deal found 7/27![American Airlines logo]()
$925
This LATAM Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:00 am
SAT
- SCL
2 stops21h 00m
LATAM Airlines
Tue 9/155:10 am
SCL
- SAT
2 stops20h 58m
LATAM Airlines
Deal found 7/25![LATAM Airlines logo]()
$929
This LATAM Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:22 pm
SAT
- SCL
2 stops21h 38m
LATAM Airlines
Sun 11/19:50 pm
SCL
- SAT
2 stops28h 38m
LATAM Airlines
Deal found 7/25![LATAM Airlines logo]()
$935
This oojo deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am
SAT
- SCL
2 stops22h 55m
LATAM Airlines
Sun 10/410:30 pm
SCL
- SAT
2 stops27h 38m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$952
Best flights from San Antonio to SantiagoDiscover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:03 pm
SAT
- SCL
2 stops15h 57m
American Airlines
Thu 9/179:30 pm
SCL
- SAT
2 stops17h 37m
American Airlines
Deal found 7/27![American Airlines logo]()
$925
This oojo deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:06 am
SAT
- SCL
2 stops17h 49m
LATAM Airlines
Tue 9/159:30 am
SCL
- SAT
3 stops29h 19m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$928
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:21 pm
SAT
- SCL
2 stops20h 39m
Delta
Thu 9/178:40 pm
SCL
- SAT
1 stop15h 07m
Delta
Deal found 7/28![Delta logo]()
$935
This lastminute.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:21 pm
SAT
- SCL
1 stop13h 54m
LATAM Airlines
Thu 9/178:40 pm
SCL
- SAT
1 stop15h 07m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$930
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1910:45 am
SAT
- SCL
1 stop16h 55m
Delta
Thu 2/48:30 pm
SCL
- SAT
2 stops21h 58m
Delta
Deal found 7/26![Delta logo]()
$935
This LATAM Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:20 pm
SAT
- SCL
2 stops21h 40m
LATAM Airlines
Sun 11/19:50 pm
SCL
- SAT
2 stops28h 36m
LATAM Airlines
Deal found 7/28![LATAM Airlines logo]()
$935
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:21 pm
SAT
- SCL
1 stop13h 54m
Delta
Tue 9/158:40 pm
SCL
- SAT
1 stop20h 32m
Delta
Deal found 7/27![Delta logo]()
$935
Last-minute flights from San Antonio to SantiagoDiscover last-minute flight deals from San Antonio to Santiago. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Santiago. Data last updated July 29, 2026 and is based on user searches.
This oojo deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:46 am
SAT
- SCL
2 stops19h 09m
LATAM Airlines
Fri 8/148:30 am
SCL
- SAT
3 stops30h 08m
LATAM Airlines
Deal found 7/29![LATAM Airlines logo]()
$1,313
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:55 am
SAT
- SCL
2 stops21h 00m
Delta
Fri 8/1411:25 pm
SCL
- SAT
1 stop17h 34m
Delta
Deal found 7/29![Delta logo]()
$1,339
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:11 pm
SAT
- SCL
1 stop11h 54m
American Airlines
Fri 8/148:50 pm
SCL
- SAT
1 stop28h 09m
American Airlines
Deal found 7/29![American Airlines logo]()
$1,402
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:00 pm
SAT
- SCL
2 stops14h 00m
United Airlines
Fri 8/144:14 am
SCL
- SAT
2 stops19h 25m
United Airlines
Deal found 7/28![United Airlines logo]()
$1,677
This oojo deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:45 pm
SAT
- SCL
2 stops36h 10m
LATAM Airlines
Thu 8/278:30 am
SCL
- SAT
3 stops27h 40m
LATAM Airlines
Deal found 7/28![LATAM Airlines logo]()
$913
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:46 am
SAT
- SCL
2 stops18h 09m
Delta
Thu 8/2711:25 pm
SCL
- SAT
1 stop25h 31m
Delta
Deal found 7/28![Delta logo]()
$935
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:56 pm
SAT
- SCL
3 stops29h 50m
Multiple Airlines
Thu 8/277:50 am
SCL
- SAT
3 stops27h 25m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$1,032
One-way flights from San Antonio to SantiagoSearch for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/264:53 pm
SAT
- SCL
3 stops59h 21m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:56 pm
SAT
- SCL
3 stops28h 39m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1112:38 pm
SAT
- SCL
3 stops28h 33m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$471
This SmartFares deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:20 pm
SAT
- SCL
1 stop29h 55m
Aeromexico
Deal found 7/25![Aeromexico logo]()
$508
This Cheapflightsfares deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:45 pm
SAT
- SCL
1 stop12h 30m
LATAM Airlines
Deal found 7/24![LATAM Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:00 am
SAT
- SCL
2 stops22h 00m
American Airlines
Deal found 7/25![American Airlines logo]()
$635
This LATAM Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:41 pm
SAT
- SCL
3 stops21h 44m
LATAM Airlines
Deal found 7/25![LATAM Airlines logo]()
$665
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:15 pm
SAT
- SCL
1 stop15h 35m
United Airlines
Deal found 7/27![United Airlines logo]()
$705
Find flight deals from San Antonio to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $699 (Trip.com) |
One-way from | $354 (Kiwi.com) |
Popular in | June |
Cheapest in | September |
Average price | $1,219 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Thu 9/10
2:03 pm-8:00 am
2 stops15h 57m
Santiago Arturo Merino Benitez
Thu 9/17
9:30 pm-1:07 pm
2 stops17h 37m
$925
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Tue 9/8
11:06 am-6:55 am
2 stops17h 49m
Santiago Arturo Merino Benitez
Tue 9/15
9:30 am-12:49 pm
3 stops29h 19m
$928
Quickest round-trip
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Thu 9/10
4:21 pm-8:15 am
1 stop13h 54m
Santiago Arturo Merino Benitez
Thu 9/17
8:40 pm-9:47 am
1 stop15h 07m
$930
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Thu 9/10
4:21 pm-3:00 pm
2 stops20h 39m
Santiago Arturo Merino Benitez
Thu 9/17
8:40 pm-9:47 am
1 stop15h 07m
$935
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Tue 1/19
10:45 am-6:40 am
1 stop16h 55m
Santiago Arturo Merino Benitez
Thu 2/4
8:30 pm-3:28 pm
2 stops21h 58m
$935
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Wed 10/28
6:20 pm-6:00 pm
2 stops21h 40m
Santiago Arturo Merino Benitez
Sun 11/1
9:50 pm-11:26 pm
2 stops28h 36m
$935
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Tue 9/8
4:21 pm-8:15 am
1 stop13h 54m
Santiago Arturo Merino Benitez
Tue 9/15
8:40 pm-3:12 pm
1 stop20h 32m
$935
Cheapest one-way
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Wed 8/26
4:53 pm-5:14 am
3 stops59h 21m
$354
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Wed 9/9
8:56 pm-3:35 am
3 stops28h 39m
$366
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Fri 12/11
9:17 pm-5:03 am
2 stops52h 46m
$547
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
SAT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 29, 2026.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentStacey-Ann,Aug 2023
IAH - ATL
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentStacey-Ann,Aug 2023
IAH - ATL
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentStacey-Ann,Aug 2023
IAH - ATL
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentStacey-Ann,Aug 2023
IAH - ATL
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Popular flights
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Alternative routes for San Antonio to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Antonio to Santiago by cabin class
Find flights from San Antonio to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Antonio and Santiago flights
Browse other San Antonio and Santiago flight options. Last updated on July 29, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on July 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 29, 2026.
Top 3 airlines flying from San Antonio to Santiago
Discover the top 3 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$566 | Average$875 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$637 | Average$1,179 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$783 | Average$1,139 | FlexibilityNo cancel fee | On-time71% |