$475+ Cheap flights from San Antonio (SAT) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
May 29 — Jun 51
Round-trip
1 adult, Economy
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Cheapest flights from San Antonio to SantiagoExplore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:00 pm
SAT
- SCL
1 stop17h 50m
American Airlines
Tue 10/69:30 pm
SCL
- SAT
1 stop22h 12m
American Airlines
Deal found 4/28![American Airlines logo]()
$875
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:04 pm
SAT
- SCL
1 stop11h 46m
American Airlines
Tue 11/1010:15 pm
SCL
- SAT
1 stop28h 42m
American Airlines
Deal found 4/27![American Airlines logo]()
$887
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:16 pm
SAT
- SCL
3 stops27h 19m
Multiple Airlines
Thu 7/233:20 pm
SCL
- SAT
2 stops28h 17m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$894
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:25 pm
SAT
- SCL
1 stop13h 50m
Delta
Mon 10/58:40 pm
SCL
- SAT
1 stop15h 14m
Delta
Deal found 4/28![Delta logo]()
$915
This KAYAK deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:10 pm
SAT
- SCL
3 stops21h 15m
LATAM Airlines
Tue 10/277:45 am
SCL
- SAT
2 stops18h 43m
LATAM Airlines
Deal found 4/28![LATAM Airlines logo]()
$920
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:10 pm
SAT
- SCL
1 stop35h 25m
Delta
Wed 10/77:15 am
SCL
- SAT
2 stops19h 13m
Delta
Deal found 4/28![Delta logo]()
$926
This Expedia deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:10 pm
SAT
- SCL
1 stop16h 05m
LATAM Airlines
Tue 10/2712:10 am
SCL
- SAT
1 stop13h 16m
LATAM Airlines
Deal found 4/28![LATAM Airlines logo]()
$936
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:45 am
SAT
- SCL
2 stops20h 15m
Delta
Mon 11/3011:25 pm
SCL
- SAT
1 stop26h 53m
Delta
Deal found 4/28![Delta logo]()
$965
This KAYAK deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:25 pm
SAT
- SCL
1 stop12h 15m
LATAM Airlines
Fri 11/2711:05 pm
SCL
- SAT
2 stops21h 13m
LATAM Airlines
Deal found 4/28![LATAM Airlines logo]()
$970
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:10 pm
SAT
- SCL
1 stop35h 25m
Delta
Sun 10/411:25 pm
SCL
- SAT
1 stop17h 17m
Delta
Deal found 4/28![Delta logo]()
$976
Best flights from San Antonio to SantiagoDiscover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:03 am
SAT
- SCL
2 stops18h 47m
American Airlines
Tue 11/1010:15 pm
SCL
- SAT
2 stops16h 48m
American Airlines
Deal found 4/27![American Airlines logo]()
$880
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:15 pm
SAT
- SCL
1 stop18h 00m
Delta
Wed 10/711:25 pm
SCL
- SAT
1 stop17h 14m
Delta
Deal found 4/28![Delta logo]()
$915
This FlightHub deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/152:10 pm
SAT
- SCL
2 stops15h 45m
LATAM Airlines
Sat 8/2911:00 pm
SCL
- SAT
2 stops22h 10m
LATAM Airlines
Deal found 4/25![LATAM Airlines logo]()
$1,023
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:45 am
SAT
- SCL
1 stop23h 30m
Delta
Mon 10/57:15 am
SCL
- SAT
2 stops19h 00m
Delta
Deal found 4/28![Delta logo]()
$915
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:10 pm
SAT
- SCL
1 stop35h 25m
Delta
Mon 10/57:45 pm
SCL
- SAT
2 stops19h 37m
Delta
Deal found 4/28![Delta logo]()
$926
This KAYAK deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:38 am
SAT
- SCL
2 stops18h 22m
LATAM Airlines
Sat 8/1511:05 pm
SCL
- SAT
2 stops22h 05m
LATAM Airlines
Deal found 4/25![LATAM Airlines logo]()
$1,057
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:51 am
SAT
- SCL
2 stops19h 14m
American Airlines
Thu 7/239:00 pm
SCL
- SAT
2 stops15h 52m
American Airlines
Deal found 4/26![American Airlines logo]()
$1,065
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/274:10 pm
SAT
- SCL
1 stop35h 25m
Delta
Sun 10/47:45 pm
SCL
- SAT
2 stops19h 22m
Delta
Deal found 4/28![Delta logo]()
$926
Last-minute flights from San Antonio to SantiagoDiscover last-minute flight deals from San Antonio to Santiago. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Santiago. Data last updated April 29, 2026 and is based on user searches.
This SmartFares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:00 pm
SAT
- SCL
1 stop13h 15m
LATAM Airlines
Thu 4/308:40 pm
SCL
- SAT
1 stop14h 06m
LATAM Airlines
Deal found 4/24![LATAM Airlines logo]()
$1,486
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:00 am
SAT
- SCL
2 stops21h 05m
American Airlines
Mon 5/259:00 pm
SCL
- SAT
2 stops18h 56m
American Airlines
Deal found 4/27![American Airlines logo]()
$1,250
This FlightHub deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:00 pm
SAT
- SCL
3 stops20h 25m
LATAM Airlines
Mon 5/254:10 am
SCL
- SAT
2 stops21h 34m
LATAM Airlines
Deal found 4/25![LATAM Airlines logo]()
$1,348
This LATAM Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:27 pm
SAT
- SCL
1 stop15h 48m
LATAM Airlines
Sat 5/3011:00 pm
SCL
- SAT
2 stops22h 28m
LATAM Airlines
Deal found 4/24![LATAM Airlines logo]()
$1,229
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:44 pm
SAT
- SCL
2 stops16h 21m
American Airlines
Sat 5/309:00 pm
SCL
- SAT
1 stop27h 59m
American Airlines
Deal found 4/27![American Airlines logo]()
$1,265
One-way flights from San Antonio to SantiagoSearch for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:04 pm
SAT
- SCL
3 stops31h 21m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$475
This Cheapflightsfares deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:21 pm
SAT
- SCL
1 stop15h 54m
LATAM Airlines
Deal found 4/25![LATAM Airlines logo]()
$596
Find flight deals from San Antonio to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $875 (American Airlines) |
One-way from | $475 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $1,429 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Wed 10/21
11:03 am-7:50 am
2 stops18h 47m
Santiago Arturo Merino Benitez
Tue 11/10
10:15 pm-12:03 pm
2 stops16h 48m
$880
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Mon 9/28
12:15 pm-8:15 am
1 stop18h 00m
Santiago Arturo Merino Benitez
Wed 10/7
11:25 pm-2:39 pm
1 stop17h 14m
$915
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Mon 9/28
6:45 am-8:15 am
1 stop23h 30m
Santiago Arturo Merino Benitez
Mon 10/5
7:15 am-12:15 am
2 stops19h 00m
$915
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Sun 9/27
4:10 pm-5:35 am
1 stop35h 25m
Santiago Arturo Merino Benitez
Mon 10/5
7:45 pm-1:22 pm
2 stops19h 37m
$926
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Sun 9/27
4:10 pm-5:35 am
1 stop35h 25m
Santiago Arturo Merino Benitez
Sun 10/4
7:45 pm-1:07 pm
2 stops19h 22m
$926
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Sat 8/15
2:10 pm-6:55 am
2 stops15h 45m
Santiago Arturo Merino Benitez
Sat 8/29
11:00 pm-8:10 pm
2 stops22h 10m
$1,023
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Fri 8/7
10:38 am-6:00 am
2 stops18h 22m
Santiago Arturo Merino Benitez
Sat 8/15
11:05 pm-8:10 pm
2 stops22h 05m
$1,057
Quickest round-trip
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Tue 6/9
10:51 am-7:05 am
2 stops19h 14m
Santiago Arturo Merino Benitez
Thu 7/23
9:00 pm-11:52 am
2 stops15h 52m
$1,065
Cheapest one-way
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Thu 8/6
7:04 pm-3:25 am
3 stops31h 21m
$475
Quickest one-way
San AntonioSantiago
SAT - SCL
SATSCL
San Antonio
Thu 8/6
2:21 pm-7:15 am
1 stop15h 54m
$596
Sorted by cheapest first
Compare providers for flights from San Antonio to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
SAT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Santiago
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 29, 2026.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as LATAM Airlines,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.0
Crew
8.0
Food
6.7
Overall
7.4
Boarding
7.5
Comfort
7.3
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Entertainment
7.0
Crew
8.0
Food
6.7
Overall
7.4
Boarding
7.5
Comfort
7.3
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Entertainment
7.0
Crew
8.0
Food
6.7
Overall
7.4
Boarding
7.5
Comfort
7.3
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Entertainment
7.0
Crew
8.0
Food
6.7
Overall
7.4
Boarding
7.5
Comfort
7.3
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Antonio to Santiago
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Complete your trip
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San Antonio and Santiago flights
Browse other San Antonio and Santiago flight options. Last updated on April 29, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Top 3 airlines flying from San Antonio to Santiago
Discover the top 3 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$566 | Average$875 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$738 | Average$1,098 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$783 | Average$1,139 | FlexibilityNo cancel fee | On-time71% |