$373+ Cheap flights from San Antonio (SAT) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SCL
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from San Antonio to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Santiago
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Best
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Cheapest flights from San Antonio to SantiagoExplore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from San Antonio to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:45 pm -
2 stops28h 01m
Wed 11/411:25 pm -
1 stop18h 55m
Deal found 9/13![Multiple Airlines logo]()
$949
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:03 am -
2 stops32h 16m
Mon 11/29:35 am -
1 stop25h 31m
Deal found 9/10![Multiple Airlines logo]()
$987
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/318:53 pm -
1 stop21h 22m
Thu 1/710:12 pm -
2 stops20h 08m
Deal found 9/13![Multiple Airlines logo]()
$990
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:10 am -
1 stop25h 25m
Wed 11/410:30 pm -
1 stop26h 49m
Deal found 9/13![American Airlines logo]()
$1,002
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop24h 20m
Wed 11/410:45 pm -
1 stop12h 44m
Deal found 9/13![United Airlines logo]()
$1,007
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am -
1 stop25h 25m
Mon 11/210:30 pm -
1 stop26h 49m
Deal found 9/10![American Airlines logo]()
$1,010
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:16 am -
2 stops20h 04m
Mon 12/79:50 pm -
1 stop20h 45m
Deal found 9/12![Delta logo]()
$1,015
This LATAM Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:54 am -
3 stops25h 06m
Mon 12/711:10 pm -
2 stops16h 30m
Deal found 9/12![LATAM Airlines logo]()
$1,020
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:00 am -
2 stops19h 40m
Wed 9/308:40 pm -
1 stop20h 32m
Deal found 9/10![Delta logo]()
$1,035
Best flights from San Antonio to SantiagoDiscover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from San Antonio to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This Despegar deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2012:20 pm -
1 stop29h 55m
Sat 2/2711:25 pm -
1 stop14h 10m
Deal found 9/9![Aeromexico logo]()
$975
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am -
1 stop25h 25m
Mon 11/210:30 pm -
1 stop26h 49m
Deal found 9/10![American Airlines logo]()
$1,010
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:16 am -
2 stops20h 04m
Mon 12/79:50 pm -
1 stop20h 45m
Deal found 9/12![Delta logo]()
$1,015
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/208:00 am -
3 stops24h 41m
Sat 2/278:40 am -
2 stops18h 48m
Deal found 9/9![LATAM Airlines logo]()
$1,024
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:20 pm -
1 stop15h 30m
Sun 11/110:45 pm -
1 stop22h 20m
Deal found 9/9![United Airlines logo]()
$1,065
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/318:53 pm -
1 stop21h 22m
Thu 1/74:15 pm -
3 stops30h 02m
Deal found 9/13![Multiple Airlines logo]()
$1,192
This LATAM Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:48 am -
2 stops18h 42m
Sun 11/14:35 pm -
2 stops27h 39m
Deal found 9/13![LATAM Airlines logo]()
$1,055
Last-minute flights from San Antonio to SantiagoDiscover last-minute flight deals from San Antonio to Santiago. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Santiago. Data last updated September 14, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:00 am -
2 stops19h 40m
Wed 9/308:40 pm -
1 stop20h 32m
Deal found 9/10![Delta logo]()
$1,035
This SmartFares deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:41 pm -
1 stop16h 34m
Thu 10/2911:10 pm -
1 stop15h 25m
Deal found 9/12![LATAM Airlines logo]()
$1,041
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:03 am -
2 stops32h 16m
Mon 11/29:35 am -
1 stop25h 31m
Deal found 9/10![Multiple Airlines logo]()
$987
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am -
1 stop25h 25m
Mon 11/210:30 pm -
1 stop26h 49m
Deal found 9/10![American Airlines logo]()
$1,010
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:45 pm -
2 stops28h 01m
Wed 11/411:25 pm -
1 stop18h 55m
Deal found 9/13![Multiple Airlines logo]()
$949
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:10 am -
1 stop25h 25m
Wed 11/410:30 pm -
1 stop26h 49m
Deal found 9/13![American Airlines logo]()
$1,002
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop24h 20m
Wed 11/410:45 pm -
1 stop12h 44m
Deal found 9/13![United Airlines logo]()
$1,007
One-way flights from San Antonio to SantiagoSearch for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from San Antonio to Santiago. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:25 am -
3 stops40h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:05 pm -
2 stops33h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$423
This Cheapflightsfares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:00 am -
1 stop22h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![LATAM Airlines logo]()
$717
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:35 am -
1 stop23h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Delta logo]()
$736
This FlightHub deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:37 pm -
3 stops23h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![LATAM Airlines logo]()
$991
This BusinessClass deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:15 am -
2 stops18h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Copa Airlines logo]()
$1,266
This KAYAK deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/188:00 am -
1 stop20h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![GOL logo]()
$1,317
Find flight deals from San Antonio to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $945 (United Airlines) |
One-way from | $373 (Kiwi.com) |
Popular in | October |
Cheapest in | March |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from San Antonio to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Sun 10/4
9:25 am-3:56 am
3 stops40h 31m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$373
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Sat 10/3
12:05 pm-11:39 pm
2 stops33h 34m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$423
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Sun 10/4
8:00 am-8:15 am
1 stop22h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$717
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Sat 10/3
6:35 am-8:15 am
1 stop23h 40m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$736
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Sat 2/20
12:20 pm-9:15 pm
1 stop29h 55m
Santiago Arturo Merino Benitez
Sat 2/27
11:25 pm-10:35 am
1 stop14h 10m
$975
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Fri 12/18
6:37 pm-9:30 pm
3 stops23h 53m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$991
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Mon 10/26
5:10 am-8:35 am
1 stop25h 25m
Santiago Arturo Merino Benitez
Mon 11/2
10:30 pm-10:19 pm
1 stop26h 49m
$1,010
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Tue 12/1
6:16 am-5:20 am
2 stops20h 04m
Santiago Arturo Merino Benitez
Mon 12/7
9:50 pm-3:35 pm
1 stop20h 45m
$1,015
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Sat 2/20
8:00 am-11:41 am
3 stops24h 41m
Santiago Arturo Merino Benitez
Sat 2/27
8:40 am-12:28 am
2 stops18h 48m
$1,024
San AntonioSantiago
SAT San Antonio - SCL Santiago Arturo Merino Benitez
SATSCL
San Antonio
Wed 10/28
10:48 am-7:30 am
2 stops18h 42m
Santiago Arturo Merino Benitez
Sun 11/1
4:35 pm-5:14 pm
2 stops27h 39m
$1,055
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Antonio-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Antonio-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Antonio with our price prediction graph.
SAT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 14, 2026.
Read through reviews of airlines operating flights from San Antonio to Santiago, such as LATAM Airlines,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.0
Food
6.7
Overall
7.4
Comfort
7.3
Boarding
7.5
Crew
8.0
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Entertainment
7.0
Food
6.7
Overall
7.4
Comfort
7.3
Boarding
7.5
Crew
8.0
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Entertainment
7.0
Food
6.7
Overall
7.4
Comfort
7.3
Boarding
7.5
Crew
8.0
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Entertainment
7.0
Food
6.7
Overall
7.4
Comfort
7.3
Boarding
7.5
Crew
8.0
Reviews
1 / 20
8.0
ExcellentNoah,Aug 2026
JFK - GRU
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Antonio to Santiago
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Complete your trip
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Search flights from San Antonio to Santiago by cabin class
Find flights from San Antonio to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Antonio and Santiago flights
Browse other San Antonio and Santiago flight options. Last updated on September 14, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Top 3 airlines flying from San Antonio to Santiago
Discover the top 3 airlines that operate flights from San Antonio to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$738 | Average$1,256 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$752 | Average$875 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$805 | Average$1,414 | FlexibilityNo cancel fee | On-time71% |