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South America

$123+ Cheap flights from San Antonio (SAT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — BOG
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
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Cheap flight deals from San Antonio to South America

Cheapest flights from San Antonio to South America
Explore the most affordable flight options available from San Antonio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

This KAYAK deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
SAT
-
MDE
1 stop6h 55m
Spirit Airlines
Mon 3/161:17 am
MDE
-
SAT
1 stop8h 15m
Spirit Airlines
Deal found 1/20$317
This Cheapflightsfares deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
SAT
-
MDE
1 stop6h 55m
Spirit Airlines
Fri 2/273:15 pm
MDE
-
SAT
1 stop19h 15m
Spirit Airlines
Deal found 1/19$328
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:26 am
SAT
-
CTG
1 stop25h 44m
Spirit Airlines
Mon 3/91:21 pm
CTG
-
SAT
1 stop20h 09m
Spirit Airlines
Deal found 1/19$338
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:00 am
SAT
-
BOG
1 stop29h 47m
Spirit Airlines
Tue 2/241:45 pm
BOG
-
SAT
1 stop11h 14m
Spirit Airlines
Deal found 1/20$340
This Cheapflightsfares deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/156:00 am
SAT
-
MDE
1 stop6h 55m
Spirit Airlines
Sat 2/282:50 pm
MDE
-
SAT
1 stop10h 09m
Spirit Airlines
Deal found 1/18$340
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:26 am
SAT
-
BOG
1 stop26h 44m
Spirit Airlines
Tue 2/243:06 pm
BOG
-
SAT
1 stop19h 24m
Spirit Airlines
Deal found 1/19$347
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1410:26 am
SAT
-
MDE
1 stop26h 47m
Spirit Airlines
Tue 2/173:15 pm
MDE
-
SAT
1 stop19h 15m
Spirit Airlines
Deal found 1/19$349
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:04 pm
SAT
-
BOG
2 stops20h 06m
Multiple Airlines
Tue 2/243:06 pm
BOG
-
SAT
1 stop19h 24m
Multiple Airlines
Deal found 1/19$358
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:26 am
SAT
-
CTG
1 stop25h 47m
Spirit Airlines
Mon 4/271:21 pm
CTG
-
SAT
1 stop20h 09m
Spirit Airlines
Deal found 1/19$367
This KAYAK deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1310:26 am
SAT
-
MDE
1 stop26h 47m
Spirit Airlines
Tue 2/173:15 pm
MDE
-
SAT
1 stop19h 15m
Spirit Airlines
Deal found 1/19$378
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:26 am
SAT
-
CTG
1 stop25h 44m
Spirit Airlines
Thu 3/121:24 pm
CTG
-
SAT
1 stop20h 08m
Spirit Airlines
Deal found 1/18$382
This Avianca Connect deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:26 am
SAT
-
MDE
1 stop10h 14m
Multiple Airlines
Tue 3/171:00 pm
MDE
-
SAT
1 stop20h 32m
Multiple Airlines
Deal found 1/20$383

Find flight deals from San Antonio to South America

Keep the following information in mind while searching for San Antonio to South America flight deals. Data was last updated January 20, 2026.

Round-trip from

$317
(KAYAK)

One-way from

$123
(Trip.com)

Popular in

July

Cheapest in

January

Average price

$388
From San Antonio to South America
Search Deals
One-way flight from San Antonio to South America
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($83 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from San Antonio to South America that are best for you.

Fly from

San Antonio

Fly to

South America

Route

Depart

Return

Price

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Tue 3/3

6:00 am-1:55 pm

1 stop6h 55m

Medellín Jose Maria Cordova Intl

Mon 3/16

1:17 am-9:32 am

1 stop8h 15m

$317

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Tue 2/24

6:00 am-1:55 pm

1 stop6h 55m

Medellín Jose Maria Cordova Intl

Fri 2/27

3:15 pm-9:30 am

1 stop19h 15m

$328

San AntonioCartagena

SAT - CTG

SATCTG

San Antonio

Wed 3/4

10:26 am-1:10 pm

1 stop25h 44m

Cartagena Rafael Nunez

Mon 3/9

1:21 pm-9:30 am

1 stop20h 09m

$338

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sun 2/15

6:00 am-1:55 pm

1 stop6h 55m

Medellín Jose Maria Cordova Intl

Sat 2/28

2:50 pm-11:59 pm

1 stop10h 09m

$340

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Sat 2/14

10:26 am-2:13 pm

1 stop26h 47m

Medellín Jose Maria Cordova Intl

Tue 2/17

3:15 pm-9:30 am

1 stop19h 15m

$349

San AntonioCartagena

SAT - CTG

SATCTG

San Antonio

Wed 4/22

10:26 am-12:13 pm

1 stop25h 47m

Cartagena Rafael Nunez

Mon 4/27

1:21 pm-9:30 am

1 stop20h 09m

$367

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Tue 3/3

10:26 am-9:40 pm

1 stop10h 14m

Medellín Jose Maria Cordova Intl

Tue 3/17

1:00 pm-9:32 am

1 stop20h 32m

$383

San AntonioCartagena

SAT - CTG

SATCTG

San Antonio

Fri 3/20

10:27 am-12:19 pm

1 stop25h 52m

Cartagena Rafael Nunez

Mon 3/23

1:24 pm-9:32 am

1 stop20h 08m

$389

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Mon 2/16

6:00 am-1:55 pm

1 stop6h 55m

Medellín Jose Maria Cordova Intl

Mon 2/23

3:15 pm-9:30 am

1 stop19h 15m

$394

San AntonioMedellín

SAT - MDE

SATMDE

San Antonio

Fri 2/13

10:26 am-1:55 pm

2 stops26h 29m

Medellín Jose Maria Cordova Intl

Tue 2/17

3:15 pm-9:30 am

1 stop19h 15m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 60 results
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6

Best time to book a flight from San Antonio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to South America

What is the cheapest month to book a flight from San Antonio to South America?

Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 20, 2026.
Read through reviews of airlines operating flights from San Antonio to South America, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,085 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,085 reviews
Delta
7.9
Good
8,085 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,913 reviews
Delta
7.9
Good
8,085 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,189 reviews
Delta
7.9
Good
8,085 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,169 reviews
Delta
7.9
Good
8,085 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,358 reviews
Delta
7.9
Good
8,085 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to South America?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to South America from San Antonio.

  • How long is the flight from San Antonio to South America?

    There are many flights that can get you from San Antonio to South America in 6h 55m. Fly via Spirit Airlines, United Airlines, or Delta to get the fastest option. The distance between San Antonio and South America is about 2203 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Antonio to South America one-way?

    The cheapest airlines for a one-way flight from San Antonio to South America are Delta ($162), American Airlines ($184), and United Airlines ($184).

  • What are the most popular routes from San Antonio to South America?

    When deciding which route to take from San Antonio to South America consider San Antonio - Medellín Jose Maria Cordova Intl, San Antonio - Santa Cruz de la Sierra Viru Viru Intl or San Antonio - Rio de Janeiro–Galeão Intl as they are the most popular.

  • Can I find deals for flights from San Antonio to South America that include hotel bookings?

    Yes. In addition to deals on San Antonio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to South America.

  • Can I find deals for business class flights from San Antonio to South America?

    Yes. Cheapflights offers flight deals from San Antonio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to South America?

    Currently, October is the cheapest month in which you can book a flight from San Antonio to South America (average of $103). Flying from San Antonio to South America in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Antonio to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from San Antonio to South America

Discover the top 6 airlines that operate flights from San Antonio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$285Average$345FlexibilityNo cancel feeOn-time65%
DeltaCheapest$412Average$718FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$414Average$731FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$414Average$859FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$419Average$769FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$648Average$732FlexibilityNo cancel feeOn-timeN/A

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