$226+ Cheap flights from South Carolina to La Crosse (LSE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — LSE
mar 4 — mar 111
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from South Carolina to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to La Crosse
Cheapest
Best
Last-minute
One-way
Cheapest flights from South Carolina to La CrosseExplore the most affordable flight options available from South Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on fevereiro 2, 2026.
Explore the most affordable flight options available from South Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on fevereiro 2, 2026.
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 3/1212:25 pm
CHS
- LSE
1 stop6h 34m
American Airlines
ter 3/179:48 am
LSE
- CHS
1 stop5h 56m
American Airlines
Deal found 2/1![American Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 8/296:30 am
CLT
- LSE
1 stop12h 40m
United Airlines
ter 9/18:15 pm
LSE
- CLT
1 stop19h 52m
United Airlines
Deal found 1/31![United Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 8/122:34 pm
CHS
- LSE
2 stops9h 44m
American Airlines
seg 8/1710:53 am
LSE
- CHS
2 stops10h 09m
American Airlines
Deal found 2/1![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 2/54:42 pm
CLT
- LSE
1 stop6h 34m
American Airlines
dom 2/86:00 am
LSE
- CLT
1 stop4h 16m
American Airlines
Deal found 1/31![American Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 10/276:43 pm
CHS
- LSE
1 stop15h 13m
United Airlines
sáb 10/319:42 am
LSE
- CHS
1 stop10h 22m
United Airlines
Deal found 1/30![United Airlines logo]()
$584
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 10/2711:45 am
SAV
- LSE
2 stops13h 30m
United Airlines
sáb 10/319:42 am
LSE
- SAV
1 stop10h 28m
United Airlines
Deal found 1/30![United Airlines logo]()
$691
Best flights from South Carolina to La CrosseDiscover carefully curated flight deals from South Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated fevereiro 2, 2026.
Discover carefully curated flight deals from South Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated fevereiro 2, 2026.
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 3/1212:25 pm
CHS
- LSE
1 stop6h 34m
American Airlines
ter 3/179:48 am
LSE
- CHS
1 stop5h 56m
American Airlines
Deal found 2/1![American Airlines logo]()
$457
Last-minute flights from South Carolina to La CrosseDiscover last-minute flight deals from South Carolina to La Crosse. Data last updated fevereiro 2, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to La Crosse. Data last updated fevereiro 2, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 2/54:42 pm
CLT
- LSE
1 stop6h 34m
American Airlines
dom 2/86:00 am
LSE
- CLT
1 stop4h 16m
American Airlines
Deal found 1/31![American Airlines logo]()
$578
One-way flights from South Carolina to La CrosseSearch for one-way flight options from South Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated fevereiro 2, 2026.
Search for one-way flight options from South Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated fevereiro 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 2/197:00 am
CLT
- LSE
3 stops28h 53m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 3/77:23 pm
CLT
- LSE
2 stops40h 30m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 2/251:24 pm
CLT
- LSE
3 stops46h 29m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 2/85:13 pm
CLT
- LSE
2 stops19h 26m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 3/58:53 am
CLT
- LSE
2 stops27h 00m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 2/155:13 pm
CLT
- LSE
2 stops18h 40m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 2/185:49 pm
CLT
- LSE
3 stops42h 04m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 2/146:43 pm
CLT
- LSE
2 stops41h 10m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 2/265:13 pm
CLT
- LSE
2 stops18h 40m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$286
Find flight deals from South Carolina to La Crosse
Keep the following information in mind while searching for South Carolina to La Crosse flight deals. Data was last updated fevereiro 2, 2026.
Round-trip from | $457 (American Airlines) |
|---|---|
One-way from | $226 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated fevereiro 2, 2026.
Use the filters below to find and compare flights from South Carolina to La Crosse that are best for you.
Fly from
South Carolina
Fly to
La Crosse
Route
Depart
Return
Price
CharlestonLa Crosse
CHS - LSE
CHSLSE
Charleston
qui 3/12
12:25 pm-5:59 pm
1 stop6h 34m
La Crosse
ter 3/17
9:48 am-4:44 pm
1 stop5h 56m
$457
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
sáb 3/7
7:23 pm-10:53 am
2 stops40h 30m
$242
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
dom 2/8
5:13 pm-11:39 am
2 stops19h 26m
$246
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
qui 3/5
8:53 am-10:53 am
2 stops27h 00m
$250
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
dom 2/15
5:13 pm-10:53 am
2 stops18h 40m
$258
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
qua 2/18
5:49 pm-10:53 am
3 stops42h 04m
$260
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
sáb 2/14
6:43 pm-10:53 am
2 stops41h 10m
$275
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
qua 2/11
2:46 pm-10:53 am
3 stops45h 07m
$312
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
qui 2/12
3:28 pm-10:53 am
2 stops20h 25m
$328
Best time to book a flight from South Carolina to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from South Carolina with our price prediction graph.
CLT-LSE
CHS-LSE
SAV-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to La Crosse
USSC-LSE
CLT-LSE
CHS-LSE
SAV-LSE
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for South Carolina to La Crosse
See prices for flight routes from nearby airports that may be better suited for you.
Top airline flying from South Carolina to La Crosse
Discover the top airline that operate flights from South Carolina to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated fevereiro 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$507 | Average$611 | FlexibilityNo cancel fee | On-time71% |