HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key West

$139+ Cheap flights from St. Louis to Key West (STL - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Key West with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Lambert-St Louis to Key West are usually found in December or August, booked 71 days in advance, depart on a Friday or Tuesday and return on a Wednesday

Cheap flight deals from St. Louis to Key West

Cheapest flights from St. Louis to Key West
Explore the most affordable flight options available from St. Louis to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/131:35 pmSTL - EYW
1 stop5h 31mDelta
Sat 12/204:47 pmEYW - STL
1 stop5h 56mDelta
Deal found 12/10$349
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:00 amSTL - EYW
1 stop6h 08mAmerican Airlines
Thu 1/16:26 pmEYW - STL
1 stop6h 18mAmerican Airlines
Deal found 12/11$350
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amSTL - EYW
2 stops9h 12mAmerican Airlines
Sat 12/201:15 pmEYW - STL
1 stop7h 16mAmerican Airlines
Deal found 12/11$354
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/212:04 pmSTL - EYW
1 stop7h 40mAmerican Airlines
Sat 12/274:03 pmEYW - STL
1 stop7h 32mAmerican Airlines
Deal found 12/10$374
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:00 amSTL - EYW
1 stop7h 07mDelta
Sat 12/2011:47 amEYW - STL
1 stop5h 41mDelta
Deal found 12/9$384
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:02 amSTL - EYW
1 stop8h 13mAmerican Airlines
Sat 12/2011:57 amEYW - STL
2 stops9h 54mAmerican Airlines
Deal found 12/9$389
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:27 pmSTL - EYW
1 stop14h 48mMultiple Airlines
Sun 1/410:37 pmEYW - STL
2 stops37h 19mMultiple Airlines
Deal found 12/10$406

Find flight deals from St. Louis to Key West

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$194
(Kiwi.com)

One-way from

$139
(Kiwi.com)

Popular in

March

Cheapest in

December

Average price

$324
Provider with most accurate pricing for Lambert-St Louis-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Key West flights.
Search Deals
From Lambert-St Louis to Key West
Search Deals
One-way flight from Lambert-St Louis to Key West
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from St. Louis to Key West that are best for you.

Fly from

St. Louis

Fly to

Key West

Route

Depart

Return

Price

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Thu 1/8

5:11 pm-12:26 pm

1 stop18h 15m

Key West

Thu 1/15

10:06 am-10:34 pm

1 stop13h 28m

$194

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 1/7

5:11 pm-9:26 am

1 stop15h 15m

Key West

Mon 1/19

2:25 pm-6:51 am

2 stops41h 26m

$202

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 2/11

8:13 am-7:10 pm

2 stops9h 57m

Key West

Wed 2/18

6:45 am-1:54 pm

2 stops8h 09m

$233

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 1/4

11:51 am-1:30 pm

1 stop24h 39m

Key West

Thu 1/8

10:06 am-10:33 pm

1 stop13h 27m

$236

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 2/1

5:42 pm-12:26 pm

1 stop17h 44m

Key West

Sun 2/8

9:46 am-6:51 am

2 stops22h 05m

$244

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Fri 1/9

6:00 am-4:07 pm

1 stop9h 07m

Key West

Tue 1/13

1:22 pm-9:15 pm

2 stops8h 53m

$246

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 1/7

8:30 am-4:22 pm

1 stop6h 52m

Key West

Wed 1/14

4:15 pm-10:58 pm

1 stop7h 43m

$251

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 1/7

6:00 am-4:07 pm

1 stop9h 07m

Key West

Fri 1/30

1:16 pm-9:15 pm

1 stop8h 59m

$259

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 2/28

3:49 pm-3:23 pm

1 stop22h 34m

Key West

Sat 3/7

11:55 am-8:47 am

2 stops21h 52m

$293

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 1/7

6:00 am-11:29 am

1 stop4h 29m

Key West

Fri 1/30

1:28 pm-8:06 pm

1 stop7h 38m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 20 results
1
2

Compare providers for flights from St. Louis to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Key West in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Key West flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Key West flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Key West

How far ahead should I book a flight from St. Louis to Key West?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Key West. Price data was last updated on December 5, 2025.

Booking 71 days in advance of your planned departure date is, on average, the best time to get cheap flights from St. Louis to Key West. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from St. Louis to Key West?

Currently, May is the cheapest month in which you can book a flight from St. Louis to Key West (average of $198). Flying from St. Louis to Key West in August is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from St. Louis to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Key West?

    Departing from St. Louis to Key West will take you 9h 57m. The distance between St. Louis and Key West is about 1102 mi.

  • What are the cheapest airlines flying from St. Louis to Key West round-trip?

    Our cheapest airline available from St. Louis to Key West is Delta. Our recent data shows that you can find tickets from as low as $216 on this airline. An additional option worth looking into is American Airlines, starting at $226. Users have found that Delta is 48% cheaper than the other options available to this destination.

  • Can I find deals for flights from St. Louis to Key West that include hotel bookings?

    Yes. In addition to deals on St. Louis to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Key West.

  • Can I find deals for business class flights from St. Louis to Key West?

    Yes. Cheapflights offers flight deals from St. Louis to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Key West?

    Currently, May is the cheapest month in which you can book a flight from St. Louis to Key West (average of $198). Flying from St. Louis to Key West in August is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Key West

See prices for flight routes from nearby airports that may be better suited for you.
St. Louis to Orlando flights
Kansas City to Orlando flights
St. Louis to Miami flights
Kansas City to Miami flights
St. Louis to Fort Lauderdale flights
St. Louis to Tampa flights
Kansas City to Fort Lauderdale flights
St. Louis to Jacksonville flights
Kansas City to Tampa flights
St. Louis to Fort Myers flights
Springfield to Orlando flights
St. Louis to Sarasota flights
Kansas City to Jacksonville flights
Kansas City to Fort Myers flights
St. Louis to West Palm Beach flights
St. Louis to Daytona Beach flights
Kansas City to West Palm Beach flights
Springfield to Fort Lauderdale flights
Kansas City to Key West flights
Kansas City to Pensacola flights
Springfield to Miami flights
St. Louis to Pensacola flights
Springfield to Tampa flights
Kansas City to Sarasota flights
St. Louis to Panama City flights
Springfield to Jacksonville flights
Kansas City to Valparaiso flights
Columbia to Jacksonville flights
Kansas City to Panama City flights
Joplin to Sarasota flights
Springfield to Sarasota flights
St. Louis to Valparaiso flights
Columbia to Orlando flights
Joplin to Tampa flights
Springfield to Pensacola flights
Kansas City to St Petersburg flights
St. Louis to Gainesville flights
Kansas City to Daytona Beach flights
Kansas City to Tallahassee flights
Springfield to Fort Myers flights
St. Louis to Melbourne flights
Kansas City to Gainesville flights
Joplin to Pensacola flights
Columbia to Miami flights
Joplin to Orlando flights
Springfield to Key West flights
Springfield to Melbourne flights
St. Louis to Tallahassee flights
Kansas City to Punta Gorda flights

Top 2 airlines flying from St. Louis to Key West

Discover the top 2 airlines that operate flights from St. Louis to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$221Average$416FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$226Average$422FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.