$125+ Cheap flights from St. Louis to Key West (STL - EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
Apr 9 — Apr 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Key West
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to Key WestExplore the most affordable flight options available from St. Louis to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from St. Louis to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:24 pm
STL
- EYW
1 stop5h 29m
American Airlines
Tue 4/216:45 am
EYW
- STL
1 stop4h 31m
American Airlines
Deal found 3/9![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- EYW
1 stop18h 27m
Multiple Airlines
Wed 5/611:46 am
EYW
- STL
2 stops23h 44m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$266
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:42 am
STL
- EYW
1 stop6h 58m
Delta
Thu 5/76:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 3/5![Delta logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:59 pm
STL
- EYW
1 stop17h 12m
Multiple Airlines
Tue 4/281:01 pm
EYW
- STL
2 stops18h 49m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:23 pm
STL
- EYW
2 stops12h 58m
Multiple Airlines
Fri 5/812:10 pm
EYW
- STL
1 stop12h 09m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:23 pm
STL
- EYW
2 stops37h 48m
Multiple Airlines
Thu 5/712:05 pm
EYW
- STL
1 stop12h 14m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$277
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:30 am
STL
- EYW
1 stop7h 21m
United Airlines
Tue 5/54:47 pm
EYW
- STL
1 stop6h 43m
United Airlines
Deal found 3/5![United Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:54 pm
STL
- EYW
1 stop15h 12m
Multiple Airlines
Sun 4/510:32 pm
EYW
- STL
2 stops36h 58m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:51 pm
STL
- EYW
1 stop15h 15m
Multiple Airlines
Sun 3/299:46 am
EYW
- STL
1 stop22h 16m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- EYW
1 stop18h 27m
Multiple Airlines
Thu 5/712:05 pm
EYW
- STL
1 stop12h 14m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:02 pm
STL
- EYW
1 stop5h 38m
Delta
Wed 5/67:33 am
EYW
- STL
1 stop5h 23m
Delta
Deal found 3/5![Delta logo]()
$286
Best flights from St. Louis to Key WestDiscover carefully curated flight deals from St. Louis to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from St. Louis to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:02 pm
STL
- EYW
1 stop5h 38m
Delta
Tue 5/126:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 3/5![Delta logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:51 pm
STL
- EYW
1 stop15h 15m
Multiple Airlines
Sun 3/299:46 am
EYW
- STL
1 stop22h 16m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:30 am
STL
- EYW
1 stop7h 12m
United Airlines
Wed 4/153:52 pm
EYW
- STL
1 stop6h 21m
United Airlines
Deal found 3/7![United Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:27 pm
STL
- EYW
1 stop5h 22m
Delta
Wed 6/36:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 3/6![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:03 pm
STL
- EYW
1 stop5h 37m
Delta
Thu 5/76:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 3/5![Delta logo]()
$314
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:00 am
STL
- EYW
1 stop8h 57m
United Airlines
Sat 4/44:38 pm
EYW
- STL
1 stop6h 50m
United Airlines
Deal found 3/6![United Airlines logo]()
$493
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
STL
- EYW
1 stop10h 23m
Delta
Wed 5/67:33 am
EYW
- STL
1 stop5h 23m
Delta
Deal found 3/5![Delta logo]()
$426
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
STL
- EYW
1 stop10h 23m
Delta
Tue 5/51:22 pm
EYW
- STL
1 stop7h 04m
Delta
Deal found 3/5![Delta logo]()
$458
Last-minute flights from St. Louis to Key WestDiscover last-minute flight deals from St. Louis to Key West. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Key West. Data last updated March 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:51 pm
STL
- EYW
1 stop15h 15m
Multiple Airlines
Sun 3/299:46 am
EYW
- STL
1 stop22h 16m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:54 pm
STL
- EYW
1 stop15h 12m
Multiple Airlines
Sun 4/510:32 pm
EYW
- STL
2 stops36h 58m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:24 pm
STL
- EYW
1 stop5h 29m
American Airlines
Tue 4/216:45 am
EYW
- STL
1 stop4h 31m
American Airlines
Deal found 3/9![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:59 pm
STL
- EYW
1 stop17h 12m
Multiple Airlines
Tue 4/281:01 pm
EYW
- STL
2 stops18h 49m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- EYW
1 stop18h 27m
Multiple Airlines
Wed 5/611:46 am
EYW
- STL
2 stops23h 44m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- EYW
1 stop18h 27m
Multiple Airlines
Thu 5/712:05 pm
EYW
- STL
1 stop12h 14m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:59 pm
STL
- EYW
1 stop18h 27m
Multiple Airlines
Fri 5/812:10 pm
EYW
- STL
1 stop12h 09m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:23 pm
STL
- EYW
2 stops37h 48m
Multiple Airlines
Thu 5/712:05 pm
EYW
- STL
1 stop12h 14m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:42 am
STL
- EYW
1 stop6h 58m
Delta
Thu 5/76:19 pm
EYW
- STL
1 stop6h 40m
Delta
Deal found 3/5![Delta logo]()
$271
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:02 pm
STL
- EYW
1 stop5h 38m
Delta
Wed 5/67:33 am
EYW
- STL
1 stop5h 23m
Delta
Deal found 3/5![Delta logo]()
$286
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:30 am
STL
- EYW
1 stop7h 21m
United Airlines
Tue 5/54:47 pm
EYW
- STL
1 stop6h 43m
United Airlines
Deal found 3/5![United Airlines logo]()
$278
One-way flights from St. Louis to Key WestSearch for one-way flight options from St. Louis to Key West. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from St. Louis to Key West. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:13 pm
STL
- EYW
2 stops13h 11m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:29 pm
STL
- EYW
2 stops16h 57m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:55 am
STL
- EYW
2 stops23h 35m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$193
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:00 am
STL
- EYW
1 stop7h 40m
American Airlines
Deal found 3/5![American Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/159:05 pm
STL
- EYW
3 stops37h 25m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$339
Find flight deals from St. Louis to Key West
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $243 (American Airlines) |
One-way from | $125 (Kiwi.com) |
Popular in | March |
Cheapest in | December |
Average price | $519 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from St. Louis to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Tue 5/5
1:02 pm-7:40 pm
1 stop5h 38m
Key West
Tue 5/12
6:19 pm-11:59 pm
1 stop6h 40m
$243
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Wed 3/25
4:51 pm-9:06 am
1 stop15h 15m
Key West
Sun 3/29
9:46 am-7:02 am
1 stop22h 16m
$281
Quickest round-trip
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Wed 5/27
1:27 pm-7:49 pm
1 stop5h 22m
Key West
Wed 6/3
6:19 pm-11:59 pm
1 stop6h 40m
$299
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Sat 5/2
1:03 pm-7:40 pm
1 stop5h 37m
Key West
Thu 5/7
6:19 pm-11:59 pm
1 stop6h 40m
$314
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Sat 4/11
8:30 am-4:42 pm
1 stop7h 12m
Key West
Wed 4/15
3:52 pm-9:13 pm
1 stop6h 21m
$323
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Fri 5/1
6:00 am-5:23 pm
1 stop10h 23m
Key West
Wed 5/6
7:33 am-11:56 am
1 stop5h 23m
$426
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Fri 5/1
6:00 am-5:23 pm
1 stop10h 23m
Key West
Tue 5/5
1:22 pm-7:26 pm
1 stop7h 04m
$458
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Sun 3/29
6:00 am-3:57 pm
1 stop8h 57m
Key West
Sat 4/4
4:38 pm-10:28 pm
1 stop6h 50m
$493
Cheapest one-way
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Sat 5/16
8:13 pm-10:24 am
2 stops13h 11m
$125
St. LouisKey West
STL - EYW
STLEYW
Lambert-St Louis
Thu 4/2
6:29 pm-12:26 pm
2 stops16h 57m
$171
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Key West in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from St. Louis with our price prediction graph.
STL-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Key West
How far ahead should I book a flight from St. Louis to Key West?
Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Key West. Price data was last updated on March 6, 2026.
Booking 71 days in advance of your planned departure date is, on average, the best time to get cheap flights from St. Louis to Key West. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from St. Louis to Key West?
Currently, May is the cheapest month in which you can book a flight from St. Louis to Key West (average of $198). Flying from St. Louis to Key West in April is currently the most expensive (average of $283). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from St. Louis to Key West?
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated March 10, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from St. Louis to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
2.0
MediocreMark,Jun 2024
SGF - ATL
Boarding
8.1
Food
7.2
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
2.0
MediocreMark,Jun 2024
SGF - ATL
Boarding
8.1
Food
7.2
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
2.0
MediocreMark,Jun 2024
SGF - ATL
Boarding
8.1
Food
7.2
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Reviews
1 / 20
2.0
MediocreMark,Jun 2024
SGF - ATL
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Key West flight routes
Other flight options
Other flights from St. Louis
Popular flights
Alternative routes for St. Louis to Key West
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Key West by cabin class
Find flights from St. Louis to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 10, 2026.
St. Louis and Key West flights
Browse other St. Louis and Key West flight options. Last updated on March 10, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on March 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Key West
Discover the top 3 airlines that operate flights from St. Louis to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$222 | Average$395 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$222 | Average$396 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$376 | Average$463 | FlexibilityNo cancel fee | On-time69% |