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Key West

$153+ Cheap flights from St. Louis to Key West (STL - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
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Cheapflights Tip: The best prices from Lambert-St Louis to Key West are usually found in August or December, booked 62 days in advance, depart on a Friday or Tuesday and return on a Wednesday

Find flight deals from St. Louis to Key West

Cheapest flights from St. Louis to Key West
Explore the most affordable flight options available from St. Louis to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/34:36 pmSTL - EYW
1 stop5h 31mAmerican Airlines
Sat 12/63:18 pmEYW - STL
1 stop6h 20mAmerican Airlines
Deal found 10/25$223
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:41 pmSTL - EYW
1 stop4h 17mDelta
Thu 12/251:02 pmEYW - STL
1 stop7h 02mDelta
Deal found 10/25$233
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:40 amSTL - EYW
1 stop4h 35mDelta
Sat 12/1312:38 pmEYW - STL
1 stop4h 30mDelta
Deal found 10/26$241
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/82:04 pmSTL - EYW
2 stops8h 03mAmerican Airlines
Sat 12/133:18 pmEYW - STL
1 stop6h 20mAmerican Airlines
Deal found 10/26$246
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:41 pmSTL - EYW
1 stop4h 17mDelta
Fri 12/267:25 amEYW - STL
1 stop5h 56mDelta
Deal found 10/25$256
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:48 amSTL - EYW
2 stops19h 19mMultiple Airlines
Thu 12/258:55 amEYW - STL
1 stop14h 38mMultiple Airlines
Deal found 10/25$259
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/154:33 pmSTL - EYW
1 stop14h 42mMultiple Airlines
Sat 11/222:24 pmEYW - STL
1 stop20h 39mMultiple Airlines
Deal found 10/27$264
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/214:27 pmSTL - EYW
1 stop19h 03mMultiple Airlines
Wed 12/247:47 amEYW - STL
2 stops26h 53mMultiple Airlines
Deal found 10/25$268
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:51 amSTL - EYW
1 stop24h 39mMultiple Airlines
Thu 12/258:55 amEYW - STL
1 stop14h 38mMultiple Airlines
Deal found 10/25$270
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:02 amSTL - EYW
1 stop8h 26mAmerican Airlines
Tue 11/182:39 pmEYW - STL
1 stop5h 51mAmerican Airlines
Deal found 10/25$274
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:51 amSTL - EYW
1 stop24h 39mMultiple Airlines
Wed 12/247:47 amEYW - STL
2 stops26h 53mMultiple Airlines
Deal found 10/25$275

Cheap flight deals from St. Louis to Key West

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$223
(American Airlines)

One-way from

$153
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$464
Provider with most accurate pricing for Lambert-St Louis-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Key West flights.
Search Deals
From Lambert-St Louis to Key West
Search Deals
One-way flight from Lambert-St Louis to Key West
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from St. Louis to Key West that are best for you.

Fly from

St. Louis

Fly to

Key West

Route

Depart

Return

Price

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Wed 3/18

11:30 am-6:30 pm

1 stop6h 00m

Key West

Wed 3/25

6:31 am-10:29 am

1 stop4h 58m

$223

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 4/14

11:51 am-5:12 pm

1 stop4h 21m

Key West

Wed 4/22

7:00 am-12:54 pm

1 stop6h 54m

$223

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 4/14

9:00 am-5:12 pm

1 stop7h 12m

Key West

Tue 4/21

6:00 pm-11:38 pm

1 stop6h 38m

$223

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 1/27

6:30 am-4:22 pm

2 stops8h 52m

Key West

Tue 2/3

4:15 pm-9:13 pm

1 stop5h 58m

$228

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 2/8

8:05 am-3:17 pm

1 stop6h 12m

Key West

Sat 2/14

4:34 pm-10:14 pm

1 stop6h 40m

$241

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Mon 12/8

11:40 am-5:15 pm

1 stop4h 35m

Key West

Sat 12/13

12:38 pm-4:08 pm

1 stop4h 30m

$241

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Fri 1/9

6:02 pm-11:56 pm

1 stop4h 54m

Key West

Tue 1/13

6:06 am-3:04 pm

2 stops9h 58m

$246

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Thu 2/26

11:51 am-7:44 pm

1 stop6h 53m

Key West

Tue 3/3

6:00 pm-11:40 pm

1 stop6h 40m

$256

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Mon 2/9

6:30 am-3:17 pm

1 stop7h 47m

Key West

Sat 2/14

4:34 pm-10:14 pm

1 stop6h 40m

$275

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 11/8

4:33 pm-8:46 pm

1 stop27h 13m

$153

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 15 results
1
2

Compare providers for flights from St. Louis to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Key West in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Key West flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Key West flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Key West

How far ahead should I book a flight from St. Louis to Key West?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Key West. Price data was last updated on October 24, 2025.

Booking 62 days in advance of your planned departure date is, on average, the best time to get cheap flights from St. Louis to Key West. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from St. Louis to Key West?

Currently, May is the cheapest month in which you can book a flight from St. Louis to Key West (average of $198). Flying from St. Louis to Key West in August is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated October 27, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from St. Louis to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,996 reviews

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
Delta
7.9
Good
7,996 reviews
Delta
7.9
Good
7,996 reviews

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
7,996 reviews

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,996 reviews

Crew

8.5

Food

7.3

Overall

7.9

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Key West?

    Departing from St. Louis to Key West will take you 4h 21m. The distance between St. Louis and Key West is about 1102 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from St. Louis to Key West round-trip?

    Our cheapest airline available from St. Louis to Key West is Delta. Our recent data shows that you can find tickets from as low as $216 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $239 and $245 round-trip. Users have found that Delta is 49% cheaper than the other options available to this destination.

  • Can I find deals for flights from St. Louis to Key West that include hotel bookings?

    Yes. In addition to deals on St. Louis to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Key West.

  • Can I find deals for business class flights from St. Louis to Key West?

    Yes. Cheapflights offers flight deals from St. Louis to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Key West?

    Currently, May is the cheapest month in which you can book a flight from St. Louis to Key West (average of $198). Flying from St. Louis to Key West in August is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from St. Louis to Key West

Discover the top 3 airlines that operate flights from St. Louis to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$217Average$446FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$240Average$426FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$245Average$534FlexibilityNo cancel feeOn-time69%

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