$95+ Cheap flights from South Carolina to Key West (EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Oct 30 — Nov 61
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Key West
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Cheapest flights from South Carolina to Key WestExplore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
1 stop3h 24m
Wed 12/210:45 am -
1 stop3h 20m
Deal found 9/28![Breeze Airways logo]()
$100
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop3h 24m
Wed 11/410:04 am -
1 stop3h 20m
Deal found 9/28![Breeze Airways logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop3h 24m
Wed 11/410:04 am -
1 stop3h 20m
Deal found 9/28![Breeze Airways logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop3h 24m
Wed 10/2810:04 am -
1 stop3h 20m
Deal found 9/26![Breeze Airways logo]()
$124
This Breeze Airways deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
1 stop3h 24m
Wed 11/1110:04 am -
1 stop3h 20m
Deal found 9/26![Breeze Airways logo]()
$125
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop3h 24m
Wed 11/410:04 am -
1 stop3h 20m
Deal found 9/28![Breeze Airways logo]()
$128
This Breeze Airways deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
1 stop3h 24m
Fri 11/1312:59 pm -
1 stop24h 25m
Deal found 9/24![Breeze Airways logo]()
$131
This Breeze Airways deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop3h 24m
Mon 11/210:59 am -
1 stop21h 39m
Deal found 9/29![Breeze Airways logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:52 pm -
1 stop12h 32m
Fri 11/612:59 pm -
1 stop7h 13m
Deal found 9/25![Breeze Airways logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:40 am -
1 stop3h 24m
Wed 12/910:45 am -
1 stop3h 20m
Deal found 9/28![Breeze Airways logo]()
$146
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:24 pm -
1 stop14h 57m
Wed 11/410:04 am -
1 stop9h 40m
Deal found 9/28![Breeze Airways logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/218:52 pm -
1 stop14h 29m
Fri 12/2512:59 pm -
1 stop7h 13m
Deal found 9/29![Breeze Airways logo]()
$176
Best flights from South Carolina to Key WestDiscover carefully curated flight deals from South Carolina to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from South Carolina to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This Breeze Airways deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop3h 24m
Wed 11/410:04 am -
1 stop3h 20m
Deal found 9/29![Breeze Airways logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop3h 24m
Mon 11/211:59 am -
2 stops20h 39m
Deal found 9/29![Multiple Airlines logo]()
$236
This Breeze Airways deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
1 stop3h 24m
Fri 11/1312:59 pm -
1 stop24h 25m
Deal found 9/24![Breeze Airways logo]()
$131
This Breeze Airways deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop3h 24m
Mon 11/210:59 am -
1 stop21h 39m
Deal found 9/29![Breeze Airways logo]()
$138
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:53 pm -
1 stop4h 08m
Sat 10/247:40 am -
1 stop5h 35m
Deal found 9/25![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:02 pm -
1 stop4h 29m
Sun 12/68:00 pm -
1 stop3h 59m
Deal found 9/27![American Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop3h 24m
Wed 11/410:04 am -
2 stops9h 10m
Deal found 9/28![Breeze Airways logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:24 pm -
1 stop14h 57m
Wed 10/1410:04 am -
1 stop9h 40m
Deal found 9/25![Breeze Airways logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:24 pm -
1 stop14h 57m
Wed 10/1410:04 am -
2 stops28h 10m
Deal found 9/25![Multiple Airlines logo]()
$318
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:58 pm -
1 stop15h 38m
Fri 12/1110:59 am -
1 stop21h 39m
Deal found 9/28![Breeze Airways logo]()
$221
This Breeze Airways deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/132:13 pm -
1 stop20h 06m
Thu 12/1710:59 am -
1 stop21h 49m
Deal found 9/27![Breeze Airways logo]()
$221
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:53 pm -
1 stop4h 08m
Sat 10/1711:38 am -
1 stop4h 48m
Deal found 9/28![Delta logo]()
$385
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:16 pm -
1 stop5h 45m
Thu 10/227:40 am -
1 stop5h 51m
Deal found 9/27![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1611:08 am -
1 stop4h 48m
Sat 2/207:54 pm -
1 stop4h 04m
Deal found 9/26![American Airlines logo]()
$441
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:27 pm -
1 stop18h 52m
Thu 12/310:59 am -
1 stop21h 49m
Deal found 9/28![Breeze Airways logo]()
$251
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:59 pm -
1 stop6h 02m
Mon 12/217:15 am -
1 stop6h 50m
Deal found 9/29![Delta logo]()
$400
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/188:52 pm -
1 stop20h 03m
Sat 12/262:37 pm -
2 stops17h 16m
Deal found 9/29![Multiple Airlines logo]()
$459
This Breeze Airways deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:52 pm -
1 stop13h 12m
Sun 12/610:59 am -
1 stop9h 00m
Deal found 9/27![Breeze Airways logo]()
$262
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:00 am -
1 stop5h 37m
Wed 11/254:43 pm -
2 stops7h 11m
Deal found 9/30![American Airlines logo]()
$525
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:39 pm -
1 stop14h 40m
Mon 11/1612:59 pm -
1 stop23h 32m
Deal found 9/28![Breeze Airways logo]()
$279
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/197:41 pm -
1 stop25h 17m
Sat 12/267:15 am -
1 stop4h 47m
Deal found 9/29![Delta logo]()
$460
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:30 am -
1 stop7h 05m
Sat 10/177:19 pm -
1 stop4h 38m
Deal found 9/28![American Airlines logo]()
$537
This Breeze Airways deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/228:57 pm -
1 stop15h 39m
Fri 2/2612:59 pm -
1 stop7h 18m
Deal found 9/25![Breeze Airways logo]()
$288
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/810:47 am -
2 stops6h 39m
Tue 1/129:58 am -
2 stops6h 48m
Deal found 9/26![American Airlines logo]()
$542
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:16 pm -
1 stop5h 45m
Mon 10/267:40 am -
1 stop26h 27m
Deal found 9/27![Delta logo]()
$513
This Breeze Airways deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/224:02 pm -
1 stop18h 17m
Mon 10/2610:59 am -
1 stop4h 48m
Deal found 9/25![Breeze Airways logo]()
$301
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:00 am -
2 stops9h 14m
Sun 12/137:18 pm -
1 stop4h 37m
Deal found 9/25![American Airlines logo]()
$605
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:58 pm -
1 stop17h 23m
Wed 10/1410:04 am -
1 stop26h 10m
Deal found 9/25![Breeze Airways logo]()
$325
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:16 pm -
1 stop5h 45m
Mon 10/267:40 am -
1 stop26h 27m
Deal found 9/27![Delta logo]()
$587
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:22 am -
2 stops10h 11m
Thu 10/291:43 pm -
2 stops8h 19m
Deal found 9/28![American Airlines logo]()
$617
Last-minute flights from South Carolina to Key WestDiscover last-minute flight deals from South Carolina to Key West. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Key West. Data last updated September 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:42 pm -
1 stop18h 37m
Wed 10/1410:04 am -
1 stop3h 20m
Deal found 9/25![Breeze Airways logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:24 pm -
1 stop14h 57m
Wed 10/1410:04 am -
1 stop9h 40m
Deal found 9/25![Breeze Airways logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:28 am -
1 stop21h 56m
Sat 10/1710:04 am -
1 stop9h 40m
Deal found 9/28![Breeze Airways logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop3h 24m
Wed 11/410:04 am -
1 stop3h 20m
Deal found 9/28![Breeze Airways logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:13 pm -
1 stop20h 06m
Tue 10/271:16 pm -
1 stop24h 08m
Deal found 9/27![Breeze Airways logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:52 pm -
1 stop12h 32m
Fri 11/612:59 pm -
1 stop7h 13m
Deal found 9/25![Breeze Airways logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop3h 24m
Wed 10/2810:04 am -
1 stop3h 20m
Deal found 9/26![Breeze Airways logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop3h 24m
Sat 10/3110:04 am -
2 stops9h 08m
Deal found 9/26![Breeze Airways logo]()
$183
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop3h 24m
Wed 11/410:04 am -
1 stop3h 20m
Deal found 9/28![Breeze Airways logo]()
$115
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:24 pm -
1 stop14h 57m
Wed 11/410:04 am -
1 stop9h 40m
Deal found 9/28![Breeze Airways logo]()
$171
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop3h 24m
Wed 11/410:04 am -
1 stop3h 20m
Deal found 9/28![Breeze Airways logo]()
$128
This Breeze Airways deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop3h 24m
Mon 11/210:59 am -
1 stop21h 39m
Deal found 9/29![Breeze Airways logo]()
$138
One-way flights from South Carolina to Key WestSearch for one-way flight options from South Carolina to Key West. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from South Carolina to Key West. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/218:52 pm -
1 stop14h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Breeze Airways logo]()
$95
This Breeze Airways deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:24 pm -
1 stop14h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Breeze Airways logo]()
$97
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:13 pm -
1 stop20h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:13 pm -
1 stop20h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/55:10 pm -
1 stop22h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Allegiant Air logo]()
$133
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/182:13 pm -
1 stop20h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:42 pm -
1 stop18h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:21 pm -
1 stop20h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:02 pm -
1 stop18h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$155
This Breeze Airways deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:58 pm -
1 stop12h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Breeze Airways logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:13 pm -
2 stops34h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:43 am -
2 stops27h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$166
Find flight deals from South Carolina to Key West
Keep the following information in mind while searching for South Carolina to Key West flight deals. Data was last updated September 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $100 (Breeze Airways) |
One-way from | $95 (Kiwi.com) |
Popular in | October |
Cheapest in | September |
Average price | $138 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleKey West
GSP Greenville - EYW Key West
GSPEYW
Greenville
Wed 10/28
8:24 pm-11:21 am
1 stop14h 57m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$97
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Thu 10/22
2:13 pm-10:19 am
1 stop20h 06m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$102
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 10/31
6:00 am-9:24 am
1 stop3h 24m
Key West
Wed 11/4
10:04 am-1:24 pm
1 stop3h 20m
$126
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 11/7
6:00 am-9:24 am
1 stop3h 24m
Key West
Fri 11/13
12:59 pm-1:24 pm
1 stop24h 25m
$131
GreenvilleKey West
GSP Greenville - EYW Key West
GSPEYW
Greenville
Fri 2/5
5:10 pm-3:17 pm
1 stop22h 07m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$133
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sun 10/18
2:13 pm-10:19 am
1 stop20h 06m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 10/31
6:00 am-9:24 am
1 stop3h 24m
Key West
Mon 11/2
10:59 am-8:38 am
1 stop21h 39m
$138
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Fri 10/16
8:58 pm-9:24 am
1 stop12h 26m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$147
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Wed 10/14
6:00 am-9:24 am
1 stop3h 24m
Key West
Wed 11/4
10:04 am-7:14 pm
2 stops9h 10m
$182
GreenvilleKey West
GSP Greenville - EYW Key West
GSPEYW
Greenville
Sat 10/10
8:24 pm-11:21 am
1 stop14h 57m
Key West
Wed 10/14
10:04 am-7:44 pm
1 stop9h 40m
$192
Showing 1-10 of 50 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from South Carolina with our price prediction graph.
CHS-EYW
GSP-EYW
CAE-EYW
MYR-EYW
FLO-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Key West
USSC-EYW
CHS-EYW
GSP-EYW
CAE-EYW
MYR-EYW
What is the cheapest month to book a flight from South Carolina to Key West?
Currently, August is the cheapest month in which you can book a flight from South Carolina to Key West (average of $366). Flying from South Carolina to Key West in October is currently the most expensive (average of $593). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to Key West?
Airfare is below average for this route at the moment.
South Carolina to Key West flights typically cost between $605 and $636 in November.The cheapest round-trip price found within the last 5 days was $100 on Breeze Airways (Nov 7-Dec 2).
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Key West flight routes
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Alternative routes for South Carolina to Key West
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Key West by cabin class
Find flights from South Carolina to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 30, 2026.
South Carolina and Key West flights
Browse other South Carolina and Key West flight options. Last updated on September 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Key West flights
Consider these flights traveling from South Carolina to Key West.
Top 4 airlines flying from South Carolina to Key West
Discover the top 4 airlines that operate flights from South Carolina to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$92 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$104 | Average$211 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$125 | Average$466 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$523 | FlexibilityNo cancel fee | On-time71% |