$70+ Cheap flights from South Carolina to Key West (EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Key West
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Cheapest flights from South Carolina to Key WestExplore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Wed 9/1610:04 am -
1 stop3h 20m
Deal found 8/5![Breeze Airways logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Sat 9/1910:04 am -
1 stop3h 20m
Deal found 8/2![Breeze Airways logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop3h 24m
Wed 9/2310:04 am -
1 stop3h 20m
Deal found 8/2![Breeze Airways logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:56 pm -
1 stop22h 17m
Wed 9/910:04 am -
1 stop3h 20m
Deal found 8/4![Breeze Airways logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop3h 24m
Wed 10/2810:04 am -
1 stop3h 20m
Deal found 8/5![Breeze Airways logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop3h 24m
Sat 10/3110:04 am -
1 stop3h 20m
Deal found 8/5![Breeze Airways logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop3h 24m
Sat 10/3110:04 am -
1 stop3h 20m
Deal found 8/5![Breeze Airways logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:13 pm -
1 stop16h 21m
Thu 8/277:53 pm -
1 stop23h 40m
Deal found 8/5![Breeze Airways logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:03 pm -
1 stop15h 21m
Fri 9/2512:59 pm -
1 stop5h 24m
Deal found 8/6![Breeze Airways logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:40 pm -
1 stop20h 51m
Thu 9/1010:59 am -
1 stop8h 50m
Deal found 8/4![Breeze Airways logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:13 pm -
1 stop16h 21m
Sun 8/167:53 pm -
1 stop23h 40m
Deal found 8/4![Breeze Airways logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:21 pm -
1 stop26h 52m
Thu 8/277:53 pm -
1 stop18h 13m
Deal found 8/3![Breeze Airways logo]()
$215
Best flights from South Carolina to Key WestDiscover carefully curated flight deals from South Carolina to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from South Carolina to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This Breeze Airways deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Sat 9/1910:04 am -
1 stop3h 20m
Deal found 8/3![Breeze Airways logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:12 pm -
1 stop15h 12m
Sat 10/3110:04 am -
2 stops22h 36m
Deal found 8/6![Multiple Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:40 am -
1 stop5h 07m
Tue 11/37:40 am -
1 stop4h 59m
Deal found 8/4![Delta logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:40 pm -
1 stop20h 51m
Thu 9/1010:59 am -
1 stop8h 50m
Deal found 8/4![Breeze Airways logo]()
$169
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:10 pm -
1 stop5h 45m
Sat 9/264:39 pm -
1 stop4h 29m
Deal found 8/6![American Airlines logo]()
$393
This Breeze Airways deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:44 pm -
1 stop14h 50m
Wed 8/1911:46 am -
1 stop3h 42m
Deal found 8/6![Breeze Airways logo]()
$181
This Breeze Airways deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop3h 24m
Thu 10/110:59 am -
1 stop21h 49m
Deal found 8/6![Breeze Airways logo]()
$187
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/266:30 am -
1 stop8h 36m
Sat 1/306:20 pm -
1 stop5h 22m
Deal found 8/3![United Airlines logo]()
$496
This Breeze Airways deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:56 pm -
1 stop22h 17m
Mon 8/2412:07 pm -
1 stop20h 31m
Deal found 8/3![Breeze Airways logo]()
$190
This Breeze Airways deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:04 pm -
1 stop19h 02m
Tue 9/81:14 pm -
1 stop24h 10m
Deal found 8/6![Breeze Airways logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:56 am -
2 stops24h 06m
Sun 10/1110:59 am -
1 stop9h 00m
Deal found 8/6![Multiple Airlines logo]()
$318
This Breeze Airways deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:58 pm -
1 stop12h 26m
Sat 9/2610:04 am -
1 stop3h 20m
Deal found 8/3![Breeze Airways logo]()
$199
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:51 pm -
1 stop5h 06m
Mon 8/247:40 am -
1 stop5h 01m
Deal found 8/4![Delta logo]()
$334
This Breeze Airways deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/232:53 pm -
1 stop20h 34m
Fri 8/2812:07 pm -
1 stop20h 41m
Deal found 8/6![Breeze Airways logo]()
$205
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:53 pm -
1 stop4h 07m
Thu 10/86:10 pm -
1 stop5h 37m
Deal found 8/6![Delta logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:41 pm -
1 stop15h 53m
Fri 8/285:03 pm -
2 stops16h 02m
Deal found 8/3![Multiple Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:39 pm -
1 stop14h 40m
Tue 11/31:16 pm -
1 stop24h 08m
Deal found 8/2![Breeze Airways logo]()
$210
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2712:00 pm -
1 stop5h 07m
Wed 12/211:43 am -
1 stop3h 46m
Deal found 8/7![Delta logo]()
$355
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:30 am -
1 stop5h 41m
Mon 11/231:17 pm -
1 stop4h 21m
Deal found 8/2![American Airlines logo]()
$457
This Breeze Airways deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:03 pm -
1 stop14h 21m
Sun 10/1110:59 am -
1 stop9h 00m
Deal found 8/6![Breeze Airways logo]()
$221
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:28 am -
1 stop5h 47m
Tue 10/207:40 am -
1 stop5h 34m
Deal found 8/6![Delta logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:21 pm -
1 stop26h 52m
Sat 9/1210:04 am -
1 stop26h 10m
Deal found 8/7![Breeze Airways logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 pm -
2 stops39h 24m
Fri 9/1812:59 pm -
1 stop22h 45m
Deal found 8/6![Multiple Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/68:45 am -
1 stop4h 23m
Wed 1/1311:45 am -
1 stop6h 58m
Deal found 8/4![Delta logo]()
$401
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:00 am -
1 stop5h 27m
Wed 11/251:17 pm -
1 stop6h 37m
Deal found 8/7![American Airlines logo]()
$547
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:45 am -
1 stop4h 01m
Tue 10/67:40 am -
1 stop5h 59m
Deal found 8/3![Delta logo]()
$401
This Breeze Airways deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:24 pm -
1 stop14h 57m
Sun 11/110:59 am -
1 stop9h 00m
Deal found 8/7![Breeze Airways logo]()
$252
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:05 pm -
2 stops22h 47m
Sat 11/142:50 pm -
1 stop7h 23m
Deal found 8/6![United Airlines logo]()
$670
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:53 pm -
1 stop4h 07m
Sat 9/267:40 am -
1 stop5h 34m
Deal found 8/3![Delta logo]()
$402
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:08 am -
2 stops11h 09m
Sat 9/191:47 pm -
2 stops7h 21m
Deal found 8/2![American Airlines logo]()
$596
Last-minute flights from South Carolina to Key WestDiscover last-minute flight deals from South Carolina to Key West. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Key West. Data last updated August 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:13 pm -
1 stop16h 21m
Sun 8/167:53 pm -
1 stop23h 40m
Deal found 8/4![Breeze Airways logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:44 pm -
1 stop14h 50m
Wed 8/1911:46 am -
1 stop3h 42m
Deal found 8/6![Breeze Airways logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:21 pm -
1 stop26h 52m
Thu 8/277:53 pm -
1 stop18h 13m
Deal found 8/3![Breeze Airways logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:21 pm -
1 stop26h 52m
Tue 9/11:14 pm -
1 stop22h 25m
Deal found 8/3![Breeze Airways logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:13 pm -
1 stop16h 21m
Thu 8/277:53 pm -
1 stop23h 40m
Deal found 8/5![Breeze Airways logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:56 pm -
1 stop22h 17m
Wed 9/910:04 am -
1 stop3h 20m
Deal found 8/4![Breeze Airways logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:40 pm -
1 stop20h 51m
Thu 9/1010:59 am -
1 stop8h 50m
Deal found 8/4![Breeze Airways logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Wed 9/1610:04 am -
1 stop3h 20m
Deal found 8/5![Breeze Airways logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Sat 9/1910:04 am -
1 stop3h 20m
Deal found 8/2![Breeze Airways logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:03 pm -
1 stop15h 21m
Fri 9/2512:59 pm -
1 stop5h 24m
Deal found 8/6![Breeze Airways logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop3h 24m
Wed 9/2310:04 am -
1 stop3h 20m
Deal found 8/2![Breeze Airways logo]()
$100
This Breeze Airways deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop3h 24m
Thu 10/110:59 am -
1 stop21h 49m
Deal found 8/7![Breeze Airways logo]()
$187
One-way flights from South Carolina to Key WestSearch for one-way flight options from South Carolina to Key West. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from South Carolina to Key West. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:56 pm -
1 stop22h 17m
Deal found 8/4![Breeze Airways logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:56 pm -
1 stop22h 17m
Deal found 8/4![Breeze Airways logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:53 pm -
1 stop20h 34m
Deal found 8/6![Breeze Airways logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:02 pm -
1 stop12h 17m
Deal found 8/6![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:44 pm -
1 stop17h 14m
Deal found 8/4![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:52 pm -
1 stop13h 35m
Deal found 8/7![Multiple Airlines logo]()
$123
This Breeze Airways deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:58 pm -
1 stop12h 26m
Deal found 8/3![Breeze Airways logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:02 pm -
1 stop12h 17m
Deal found 8/3![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:52 pm -
1 stop13h 33m
Deal found 8/4![Multiple Airlines logo]()
$128
This Breeze Airways deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:58 pm -
1 stop12h 26m
Deal found 8/6![Breeze Airways logo]()
$130
This Breeze Airways deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:04 pm -
1 stop19h 21m
Deal found 8/3![Breeze Airways logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:40 pm -
1 stop12h 39m
Deal found 8/7![Multiple Airlines logo]()
$137
Find flight deals from South Carolina to Key West
Keep the following information in mind while searching for South Carolina to Key West flight deals. Data was last updated August 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $84 (Kiwi.com) |
One-way from | $70 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $502 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Wed 9/9
6:00 am-9:24 am
1 stop3h 24m
Key West
Sat 9/19
10:04 am-1:24 pm
1 stop3h 20m
$97
GreenvilleKey West
GSP Greenville - EYW Key West
GSPEYW
Greenville
Sun 9/6
3:40 pm-12:31 pm
1 stop20h 51m
Key West
Thu 9/10
10:59 am-7:49 pm
1 stop8h 50m
$169
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Mon 8/17
9:44 pm-12:34 pm
1 stop14h 50m
Key West
Wed 8/19
11:46 am-3:28 pm
1 stop3h 42m
$181
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 9/26
6:00 am-9:24 am
1 stop3h 24m
Key West
Thu 10/1
10:59 am-8:48 am
1 stop21h 49m
$187
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Wed 8/19
8:56 pm-7:13 pm
1 stop22h 17m
Key West
Mon 8/24
12:07 pm-8:38 am
1 stop20h 31m
$190
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Tue 9/1
4:04 pm-11:06 am
1 stop19h 02m
Key West
Tue 9/8
1:14 pm-1:24 pm
1 stop24h 10m
$198
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Fri 9/11
8:58 pm-9:24 am
1 stop12h 26m
Key West
Sat 9/26
10:04 am-1:24 pm
1 stop3h 20m
$199
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sun 8/23
2:53 pm-11:27 am
1 stop20h 34m
Key West
Fri 8/28
12:07 pm-8:48 am
1 stop20h 41m
$205
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Thu 10/29
9:39 pm-12:19 pm
1 stop14h 40m
Key West
Tue 11/3
1:16 pm-1:24 pm
1 stop24h 08m
$210
GreenvilleKey West
GSP Greenville - EYW Key West
GSPEYW
Greenville
Fri 10/9
7:03 pm-9:24 am
1 stop14h 21m
Key West
Sun 10/11
10:59 am-7:59 pm
1 stop9h 00m
$221
Showing 1-10 of 53 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from South Carolina with our price prediction graph.
CHS-EYW
MYR-EYW
GSP-EYW
CAE-EYW
SAV-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Key West
USSC-EYW
CHS-EYW
MYR-EYW
GSP-EYW
CAE-EYW
What is the cheapest month to book a flight from South Carolina to Key West?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Key West (average of $371). Flying from South Carolina to Key West in December is currently the most expensive (average of $572). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Key West flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for South Carolina to Key West
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Key West by cabin class
Find flights from South Carolina to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 7, 2026.
South Carolina and Key West flights
Browse other South Carolina and Key West flight options. Last updated on August 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Key West flights
Consider these flights traveling from South Carolina to Key West.
Top 4 airlines flying from South Carolina to Key West
Discover the top 4 airlines that operate flights from South Carolina to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$92 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$124 | Average$220 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$125 | Average$467 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$515 | FlexibilityNo cancel fee | On-time71% |