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Key West

$79+ Cheap flights from South Carolina to Key West (EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Jul 23 — Jul 301
Thu 7/23
Thu 7/30
1 adult, Economy
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Cheap flight deals from South Carolina to Key West

Cheapest flights from South Carolina to Key West
Explore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
CHS
-
EYW
1 stop3h 24m
Breeze Airways
Wed 9/2310:04 am
EYW
-
CHS
1 stop3h 20m
Breeze Airways
Deal found 6/18$121
This Breeze Airways deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:56 pm
CHS
-
EYW
1 stop22h 17m
Breeze Airways
Fri 7/1012:07 pm
EYW
-
CHS
1 stop20h 41m
Breeze Airways
Deal found 6/22$153
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:56 pm
CHS
-
EYW
1 stop13h 28m
Breeze Airways
Tue 7/211:14 pm
EYW
-
CHS
1 stop26h 14m
Breeze Airways
Deal found 6/21$155
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:40 pm
GSP
-
EYW
1 stop20h 51m
Breeze Airways
Thu 7/167:53 pm
EYW
-
GSP
1 stop23h 40m
Breeze Airways
Deal found 6/18$165
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:13 pm
GSP
-
EYW
1 stop16h 21m
Breeze Airways
Mon 7/271:11 pm
EYW
-
GSP
1 stop6h 22m
Breeze Airways
Deal found 6/18$167
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:56 pm
CHS
-
EYW
1 stop22h 17m
Breeze Airways
Mon 8/1712:07 pm
EYW
-
CHS
1 stop20h 31m
Breeze Airways
Deal found 6/20$172
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:40 pm
GSP
-
EYW
1 stop20h 51m
Breeze Airways
Fri 7/171:11 pm
EYW
-
GSP
1 stop6h 22m
Breeze Airways
Deal found 6/20$181
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:56 pm
CHS
-
EYW
1 stop13h 28m
Breeze Airways
Mon 7/131:11 pm
EYW
-
CHS
1 stop20h 26m
Breeze Airways
Deal found 6/19$188
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:20 pm
CHS
-
EYW
1 stop16h 11m
Breeze Airways
Mon 8/241:11 pm
EYW
-
CHS
1 stop20h 26m
Breeze Airways
Deal found 6/22$193
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:20 am
GSP
-
EYW
1 stop6h 17m
Multiple Airlines
Mon 8/31:11 pm
EYW
-
GSP
1 stop6h 22m
Multiple Airlines
Deal found 6/20$196
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:04 pm
CHS
-
EYW
1 stop19h 21m
Breeze Airways
Fri 7/1012:07 pm
EYW
-
CHS
1 stop20h 41m
Breeze Airways
Deal found 6/22$196
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:56 pm
CHS
-
EYW
1 stop13h 28m
Breeze Airways
Wed 7/1511:46 am
EYW
-
CHS
1 stop3h 42m
Breeze Airways
Deal found 6/19$197

Find flight deals from South Carolina to Key West

Keep the following information in mind while searching for South Carolina to Key West flight deals. Data was last updated June 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$121
(Kiwi.com)

One-way from

$79
(Breeze Airways)

Popular in

March

Cheapest in

January

Average price

$567
Provider with most accurate pricing for Myrtle Beach Intl-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Key West flights.
Search Deals
From South Carolina to Key West
Search Deals
One-way flight from South Carolina to Key West
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($104 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sat 7/4

8:56 pm-7:13 pm

1 stop22h 17m

Key West

Fri 7/10

12:07 pm-8:48 am

1 stop20h 41m

$153

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sun 8/23

2:53 pm-11:27 am

1 stop20h 34m

Key West

Wed 8/26

11:46 am-3:28 pm

1 stop3h 42m

$198

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Tue 8/25

4:04 pm-11:06 am

1 stop19h 02m

Key West

Fri 8/28

12:07 pm-8:48 am

1 stop20h 41m

$200

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Sun 8/23

2:53 pm-11:27 am

1 stop20h 34m

Key West

Fri 8/28

12:07 pm-8:48 am

1 stop20h 41m

$204

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Wed 8/5

8:56 pm-7:13 pm

1 stop22h 17m

Key West

Sun 8/9

7:53 pm-2:44 pm

1 stop18h 51m

$208

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Thu 8/27

3:40 pm-12:31 pm

1 stop20h 51m

Key West

Mon 8/31

1:11 pm-7:33 pm

1 stop6h 22m

$211

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Wed 7/29

8:56 pm-7:13 pm

1 stop22h 17m

Key West

Sun 8/2

12:05 pm-8:45 am

1 stop20h 40m

$219

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Fri 8/7

3:13 pm-3:45 pm

1 stop24h 32m

Key West

Mon 8/10

1:11 pm-7:33 pm

1 stop6h 22m

$227

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Tue 7/21

4:04 pm-11:06 am

1 stop19h 02m

Key West

Tue 7/28

1:14 pm-3:28 pm

1 stop26h 14m

$246

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Thu 8/13

2:53 pm-11:27 am

1 stop20h 34m

Key West

Sun 8/16

12:05 pm-8:45 am

1 stop20h 40m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/22

Showing 1-10 of 52 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Key West

What is the cheapest month to book a flight from South Carolina to Key West?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Key West (average of $65). Flying from South Carolina to Key West in April is currently the most expensive (average of $320). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Carolina to Key West?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from South Carolina?

    For a flight from South Carolina to Key West, you will be flying into Key West. Key West (EYW) is just 2.6 mi from the center of the city.

  • How long is the flight from South Carolina to Key West?

    For as low as $309, Breeze Airways can have you in Key West from South Carolina in 4h 08m. There are 649 mi between South Carolina and Key West. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from South Carolina to Key West?

    When deciding which route to take from South Carolina to Key West consider Charlotte Douglas - Key West, Charleston - Key West or Myrtle Beach Intl - Key West as they are the most popular.

  • Can I find deals for flights from South Carolina to Key West that include hotel bookings?

    Yes. In addition to deals on South Carolina to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Key West.

  • Can I find deals for business class flights from South Carolina to Key West?

    Yes. Cheapflights offers flight deals from South Carolina to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Key West?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Key West (average of $65). Flying from South Carolina to Key West in April is currently the most expensive (average of $320). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from South Carolina to Key West

Discover the top 4 airlines that operate flights from South Carolina to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$65Average$92FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$106Average$220FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$125Average$486FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$263Average$495FlexibilityNo cancel feeOn-time71%

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