$96+ Cheap flights from South Carolina to Key West (EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Dec 14 — Dec 211
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Key West
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Cheapest flights from South Carolina to Key WestExplore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2026.
Explore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:40 am -
1 stop3h 24m
Wed 12/1610:45 am -
1 stop3h 20m
Deal found 11/14![Breeze Airways logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:58 pm -
1 stop15h 38m
Wed 12/910:45 am -
1 stop3h 20m
Deal found 11/10![Breeze Airways logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:40 am -
1 stop3h 24m
Mon 1/412:59 pm -
1 stop23h 32m
Deal found 11/13![Breeze Airways logo]()
$160
This Breeze Airways deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:40 am -
1 stop3h 24m
Tue 12/81:16 pm -
1 stop24h 49m
Deal found 11/13![Breeze Airways logo]()
$165
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:52 pm -
1 stop15h 44m
Fri 12/1112:59 pm -
1 stop7h 13m
Deal found 11/11![Breeze Airways logo]()
$175
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:02 pm -
1 stop18h 17m
Fri 12/2510:59 am -
1 stop4h 48m
Deal found 11/11![Breeze Airways logo]()
$177
This Breeze Airways deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop3h 24m
Wed 12/210:45 am -
1 stop3h 20m
Deal found 11/9![Breeze Airways logo]()
$186
This Breeze Airways deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:39 pm -
1 stop14h 40m
Mon 12/710:59 am -
1 stop21h 39m
Deal found 11/9![Breeze Airways logo]()
$201
This Breeze Airways deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:40 am -
1 stop3h 24m
Sat 12/1210:45 am -
1 stop3h 20m
Deal found 11/10![Breeze Airways logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/64:02 pm -
1 stop18h 17m
Thu 12/1010:59 am -
1 stop9h 00m
Deal found 11/9![Breeze Airways logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:43 am -
2 stops27h 36m
Fri 12/2512:59 pm -
1 stop7h 13m
Deal found 11/11![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:12 pm -
1 stop18h 24m
Mon 12/1410:59 am -
1 stop23h 06m
Deal found 11/9![Breeze Airways logo]()
$287
Best flights from South Carolina to Key WestDiscover carefully curated flight deals from South Carolina to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 14, 2026.
Discover carefully curated flight deals from South Carolina to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 14, 2026.
This Breeze Airways deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:40 am -
1 stop3h 24m
Wed 12/1610:45 am -
1 stop3h 20m
Deal found 11/9![Breeze Airways logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/42:41 pm -
1 stop19h 38m
Sat 1/94:07 pm -
2 stops41h 30m
Deal found 11/10![Multiple Airlines logo]()
$301
This Breeze Airways deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:40 am -
1 stop3h 24m
Tue 12/81:16 pm -
1 stop24h 49m
Deal found 11/13![Breeze Airways logo]()
$165
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:18 pm -
1 stop4h 52m
Wed 12/162:06 pm -
1 stop5h 50m
Deal found 11/9![Delta logo]()
$333
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:53 am -
1 stop5h 44m
Wed 12/23:41 pm -
1 stop5h 49m
Deal found 11/12![American Airlines logo]()
$389
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/11:26 pm -
1 stop23h 10m
Fri 2/510:59 am -
1 stop21h 39m
Deal found 11/11![Breeze Airways logo]()
$178
This Breeze Airways deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:32 pm -
1 stop13h 47m
Fri 12/1112:59 pm -
1 stop7h 13m
Deal found 11/13![Breeze Airways logo]()
$192
This Breeze Airways deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:39 pm -
1 stop14h 40m
Mon 12/710:59 am -
1 stop21h 39m
Deal found 11/9![Breeze Airways logo]()
$201
This Breeze Airways deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:40 am -
1 stop3h 24m
Sat 12/1210:45 am -
1 stop3h 20m
Deal found 11/10![Breeze Airways logo]()
$206
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/73:05 pm -
1 stop5h 44m
Tue 1/125:00 pm -
1 stop3h 50m
Deal found 11/10![Delta logo]()
$341
This Breeze Airways deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/88:14 pm -
1 stop15h 12m
Sat 5/1512:22 pm -
1 stop7h 12m
Deal found 11/14![Breeze Airways logo]()
$213
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:15 am -
1 stop9h 07m
Sat 2/612:59 pm -
1 stop8h 04m
Deal found 11/10![United Airlines logo]()
$787
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/63:42 pm -
1 stop18h 37m
Mon 3/810:59 am -
1 stop21h 39m
Deal found 11/11![Breeze Airways logo]()
$225
This Delta deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:35 am -
1 stop5h 13m
Mon 12/217:15 am -
1 stop6h 50m
Deal found 11/14![Delta logo]()
$408
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/86:20 pm -
1 stop4h 16m
Sat 5/158:05 am -
1 stop4h 15m
Deal found 11/12![American Airlines logo]()
$452
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/163:07 pm -
1 stop19h 32m
Fri 2/1912:59 pm -
1 stop4h 07m
Deal found 11/11![Breeze Airways logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:12 pm -
1 stop18h 24m
Mon 12/1410:59 am -
1 stop23h 06m
Deal found 11/9![Breeze Airways logo]()
$287
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:00 am -
1 stop4h 48m
Mon 12/147:25 am -
1 stop6h 08m
Deal found 11/9![Delta logo]()
$519
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/241:57 pm -
2 stops9h 00m
Sat 5/13:58 pm -
2 stops7h 59m
Deal found 11/9![American Airlines logo]()
$621
This Breeze Airways deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3011:17 am -
1 stop24h 25m
Sat 4/312:22 pm -
1 stop21h 08m
Deal found 11/14![Breeze Airways logo]()
$295
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:46 pm -
1 stop6h 11m
Wed 12/307:15 am -
1 stop6h 50m
Deal found 11/13![Delta logo]()
$580
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2312:45 pm -
1 stop5h 04m
Wed 12/303:02 pm -
1 stop4h 49m
Deal found 11/10![American Airlines logo]()
$714
This Breeze Airways deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/148:43 pm -
1 stop15h 36m
Fri 2/1912:59 pm -
1 stop4h 07m
Deal found 11/12![Breeze Airways logo]()
$335
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:46 pm -
1 stop4h 15m
Fri 12/116:06 pm -
1 stop5h 45m
Deal found 11/10![Delta logo]()
$601
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:50 am -
1 stop5h 42m
Mon 12/2111:35 am -
2 stops8h 29m
Deal found 11/10![American Airlines logo]()
$726
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/243:40 pm -
1 stop4h 03m
Sat 5/16:00 pm -
1 stop5h 35m
Deal found 11/10![Delta logo]()
$609
This Breeze Airways deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:58 pm -
1 stop13h 06m
Sun 12/610:59 am -
1 stop21h 49m
Deal found 11/12![Breeze Airways logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:25 pm -
1 stop17h 54m
Thu 12/1710:59 am -
1 stop21h 46m
Deal found 11/10![Breeze Airways logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/224:27 pm -
2 stops19h 12m
Mon 1/2512:59 pm -
1 stop7h 18m
Deal found 11/14![Breeze Airways logo]()
$377
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:53 am -
1 stop5h 17m
Sun 11/297:30 am -
1 stop5h 44m
Deal found 11/10![Delta logo]()
$807
Last-minute flights from South Carolina to Key WestDiscover last-minute flight deals from South Carolina to Key West. Data last updated November 14, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Key West. Data last updated November 14, 2026 and is based on user searches.
This Breeze Airways deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop3h 24m
Wed 12/210:45 am -
1 stop3h 20m
Deal found 11/9![Breeze Airways logo]()
$186
This Breeze Airways deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:40 am -
1 stop3h 24m
Tue 12/81:16 pm -
1 stop24h 49m
Deal found 11/13![Breeze Airways logo]()
$165
This Breeze Airways deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:39 pm -
1 stop14h 40m
Mon 12/710:59 am -
1 stop21h 39m
Deal found 11/9![Breeze Airways logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:13 pm -
1 stop20h 06m
Tue 12/810:59 am -
1 stop21h 39m
Deal found 11/11![Breeze Airways logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/64:02 pm -
1 stop18h 17m
Thu 12/1010:59 am -
1 stop9h 00m
Deal found 11/9![Breeze Airways logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:58 pm -
1 stop15h 38m
Wed 12/910:45 am -
1 stop3h 20m
Deal found 11/10![Breeze Airways logo]()
$154
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:52 pm -
1 stop15h 44m
Fri 12/1112:59 pm -
1 stop7h 13m
Deal found 11/11![Breeze Airways logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:40 am -
1 stop3h 24m
Wed 12/1610:45 am -
1 stop3h 20m
Deal found 11/14![Breeze Airways logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:40 am -
1 stop3h 24m
Mon 1/412:59 pm -
1 stop23h 32m
Deal found 11/13![Breeze Airways logo]()
$160
This Breeze Airways deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:40 am -
1 stop3h 24m
Sat 12/1210:45 am -
1 stop3h 20m
Deal found 11/10![Breeze Airways logo]()
$206
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:02 pm -
1 stop18h 17m
Fri 12/2510:59 am -
1 stop4h 48m
Deal found 11/11![Breeze Airways logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/208:43 am -
2 stops27h 36m
Fri 12/2512:59 pm -
1 stop7h 13m
Deal found 11/11![Multiple Airlines logo]()
$269
One-way flights from South Carolina to Key WestSearch for one-way flight options from South Carolina to Key West. Find affordable one-way fares based on user searches. Data last updated November 14, 2026.
Search for one-way flight options from South Carolina to Key West. Find affordable one-way fares based on user searches. Data last updated November 14, 2026.
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:52 pm -
1 stop12h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Breeze Airways logo]()
$96
This Breeze Airways deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:39 pm -
1 stop14h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Breeze Airways logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/166:25 pm -
1 stop17h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Breeze Airways logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/272:30 pm -
1 stop19h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/13![Breeze Airways logo]()
$154
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/233:42 pm -
1 stop18h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Breeze Airways logo]()
$161
This Breeze Airways deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/229:39 pm -
1 stop19h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Breeze Airways logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:52 pm -
1 stop12h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/12![Breeze Airways logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/166:25 pm -
3 stops39h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:02 pm -
1 stop18h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/12![Breeze Airways logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:33 pm -
2 stops24h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Allegiant Air logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/272:23 pm -
3 stops43h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/13![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/254:10 pm -
2 stops24h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/12![Breeze Airways logo]()
$266
Find flight deals from South Carolina to Key West
Keep the following information in mind while searching for South Carolina to Key West flight deals. Data was last updated November 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $114 (Kiwi.com) |
One-way from | $96 (Breeze Airways) |
Popular in | December |
Cheapest in | January |
Average price | $514 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 14, 2026.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleKey West
GSP Greenville - EYW Key West
GSPEYW
Greenville
Mon 11/23
8:52 pm-9:24 am
1 stop12h 32m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$96
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Thu 12/17
9:39 pm-12:19 pm
1 stop14h 40m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$109
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Wed 12/9
6:40 am-10:04 am
1 stop3h 24m
Key West
Wed 12/16
10:45 am-2:05 pm
1 stop3h 20m
$119
Myrtle BeachKey West
MYR Myrtle Beach Intl - EYW Key West
MYREYW
Myrtle Beach Intl
Tue 2/16
6:25 pm-11:39 am
1 stop17h 14m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Wed 12/23
3:42 pm-10:19 am
1 stop18h 37m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$161
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Wed 12/2
6:40 am-10:04 am
1 stop3h 24m
Key West
Tue 12/8
1:16 pm-2:05 pm
1 stop24h 49m
$165
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Tue 12/22
9:39 pm-4:55 pm
1 stop19h 16m
Key West
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$168
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Mon 2/1
1:26 pm-12:36 pm
1 stop23h 10m
Key West
Fri 2/5
10:59 am-8:38 am
1 stop21h 39m
$178
GreenvilleKey West
GSP Greenville - EYW Key West
GSPEYW
Greenville
Mon 12/7
8:32 pm-10:19 am
1 stop13h 47m
Key West
Fri 12/11
12:59 pm-8:12 pm
1 stop7h 13m
$192
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Thu 12/3
9:39 pm-12:19 pm
1 stop14h 40m
Key West
Mon 12/7
10:59 am-8:38 am
1 stop21h 39m
$201
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from South Carolina with our price prediction graph.
CHS-EYW
GSP-EYW
MYR-EYW
CAE-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Key West
USSC-EYW
CHS-EYW
GSP-EYW
MYR-EYW
CAE-EYW
What is the cheapest month to book a flight from South Carolina to Key West?
Currently, November is the cheapest month in which you can book a flight from South Carolina to Key West (average of $338). Flying from South Carolina to Key West in December is currently the most expensive (average of $607). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to Key West?
Airfare is below average for this route at the moment.
South Carolina to Key West flights typically cost between $131 and $339 in December.The cheapest round-trip price found within the last 5 days was $114 on Breeze Airways (Dec 9-Dec 16).
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to Key West
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Key West by cabin class
Find flights from South Carolina to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 14, 2026.
South Carolina and Key West flights
Browse other South Carolina and Key West flight options. Last updated on November 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
South Carolina to Key West flights
Consider these flights traveling from South Carolina to Key West.
Top 4 airlines flying from South Carolina to Key West
Discover the top 4 airlines that operate flights from South Carolina to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$92 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$101 | Average$187 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$125 | Average$465 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$532 | FlexibilityNo cancel fee | On-time71% |