$104+ Cheap flights from Key West (EYW) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Sep 10 — Sep 171
Round-trip
1 adult, Economy
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Find cheap flights from Key West to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Key West to South CarolinaExplore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
Explore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
This Breeze Airways deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:07 pm -
1 stop20h 41m
Fri 9/118:58 pm -
1 stop12h 26m
Deal found 8/11![Breeze Airways logo]()
$174
This Breeze Airways deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:07 pm -
1 stop20h 41m
Thu 9/109:39 pm -
1 stop14h 40m
Deal found 8/11![Breeze Airways logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:37 am -
2 stops13h 59m
Sat 10/246:00 am -
1 stop3h 24m
Deal found 8/10![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:11 pm -
1 stop24h 10m
Tue 9/1512:05 pm -
2 stops21h 19m
Deal found 8/11![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:59 am -
1 stop7h 22m
Tue 9/1512:05 pm -
2 stops21h 19m
Deal found 8/11![Multiple Airlines logo]()
$262
This Breeze Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:01 pm -
1 stop25h 49m
Sat 10/246:00 am -
1 stop3h 24m
Deal found 8/10![Breeze Airways logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:07 pm -
1 stop19h 54m
Mon 9/2110:56 am -
2 stops46h 28m
Deal found 8/10![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:59 am -
1 stop7h 22m
Thu 9/177:54 pm -
2 stops37h 30m
Deal found 8/8![Multiple Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:20 pm -
1 stop10h 18m
Sun 10/116:45 am -
1 stop13h 06m
Deal found 8/8![Multiple Airlines logo]()
$320
This Breeze Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:59 am -
1 stop21h 39m
Sun 10/252:13 pm -
1 stop20h 06m
Deal found 8/10![Breeze Airways logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:59 am -
1 stop21h 39m
Sun 10/1110:05 pm -
2 stops14h 14m
Deal found 8/8![Breeze Airways logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:59 am -
1 stop9h 45m
Mon 12/79:39 pm -
1 stop12h 40m
Deal found 8/10![Multiple Airlines logo]()
$388
Best flights from Key West to South CarolinaDiscover carefully curated flight deals from Key West to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
Discover carefully curated flight deals from Key West to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
This Breeze Airways deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:07 pm -
1 stop20h 41m
Fri 9/118:58 pm -
1 stop12h 26m
Deal found 8/8![Breeze Airways logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:07 pm -
1 stop19h 54m
Mon 9/2110:56 am -
2 stops46h 28m
Deal found 8/10![Multiple Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:47 pm -
1 stop3h 56m
Mon 9/2810:27 am -
1 stop4h 22m
Deal found 8/7![American Airlines logo]()
$437
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:15 pm -
1 stop6h 06m
Sat 8/296:00 am -
1 stop4h 50m
Deal found 8/10![Delta logo]()
$497
This Breeze Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:01 pm -
1 stop25h 49m
Sat 10/246:00 am -
1 stop3h 24m
Deal found 8/10![Breeze Airways logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:59 am -
1 stop7h 22m
Thu 9/179:32 am -
1 stop24h 47m
Deal found 8/8![Multiple Airlines logo]()
$288
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:20 pm -
1 stop6h 24m
Sat 9/123:00 pm -
2 stops22h 29m
Deal found 8/7![United Airlines logo]()
$674
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:20 pm -
1 stop10h 18m
Sun 10/116:45 am -
1 stop13h 06m
Deal found 8/8![Multiple Airlines logo]()
$320
This Breeze Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:59 am -
1 stop21h 39m
Sun 10/252:13 pm -
1 stop20h 06m
Deal found 8/10![Breeze Airways logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:59 am -
1 stop21h 39m
Sun 10/1110:05 pm -
2 stops14h 14m
Deal found 8/8![Breeze Airways logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:59 am -
1 stop9h 45m
Mon 12/79:39 pm -
1 stop12h 40m
Deal found 8/10![Multiple Airlines logo]()
$388
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:59 pm -
1 stop23h 32m
Mon 9/284:57 pm -
2 stops40h 27m
Deal found 8/7![Breeze Airways logo]()
$418
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:40 am -
1 stop5h 50m
Tue 9/152:25 pm -
1 stop5h 35m
Deal found 8/11![Delta logo]()
$560
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:40 pm -
2 stops8h 16m
Sat 8/299:05 am -
2 stops9h 35m
Deal found 8/10![American Airlines logo]()
$563
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:00 pm -
1 stop6h 21m
Tue 9/155:30 am -
1 stop5h 16m
Deal found 8/11![Delta logo]()
$560
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:21 am -
1 stop5h 29m
Thu 9/173:36 pm -
Nonstop2h 19m
Deal found 8/8![American Airlines logo]()
$575
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:15 am -
1 stop5h 42m
Mon 9/215:20 am -
1 stop5h 37m
Deal found 8/10![American Airlines logo]()
$610
This KAYAK deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:11 pm -
1 stop26h 17m
Thu 9/106:45 am -
2 stops28h 34m
Deal found 8/11![Breeze Airways logo]()
$579
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:35 pm -
2 stops9h 25m
Fri 9/116:20 am -
2 stops6h 57m
Deal found 8/8![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:28 pm -
2 stops6h 37m
Sun 10/257:00 am -
2 stops9h 58m
Deal found 8/10![American Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:15 pm -
2 stops24h 54m
Tue 9/12:10 pm -
2 stops23h 19m
Deal found 8/6![United Airlines logo]()
$1,046
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:09 pm -
1 stop3h 50m
Fri 8/287:26 pm -
1 stop16h 10m
Deal found 8/8![American Airlines logo]()
$691
This Booking.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:14 pm -
3 stops28h 41m
Sat 8/2912:19 pm -
2 stops22h 05m
Deal found 8/10![Breeze Airways logo]()
$842
Last-minute flights from Key West to South CarolinaDiscover last-minute flight deals from Key West to South Carolina. Data last updated August 11, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to South Carolina. Data last updated August 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:15 pm -
1 stop6h 06m
Sat 8/296:00 am -
1 stop4h 50m
Deal found 8/10![Delta logo]()
$497
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:40 pm -
2 stops8h 16m
Sat 8/299:05 am -
1 stop7h 13m
Deal found 8/10![American Airlines logo]()
$558
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:07 pm -
1 stop19h 54m
Mon 9/2110:56 am -
2 stops46h 28m
Deal found 8/10![Multiple Airlines logo]()
$279
This Breeze Airways deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:07 pm -
1 stop20h 41m
Fri 9/118:58 pm -
1 stop12h 26m
Deal found 8/11![Breeze Airways logo]()
$174
This Breeze Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:07 pm -
1 stop20h 41m
Thu 9/109:39 pm -
1 stop14h 40m
Deal found 8/10![Breeze Airways logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:11 pm -
1 stop24h 10m
Tue 9/1512:05 pm -
2 stops21h 19m
Deal found 8/11![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:59 am -
1 stop7h 22m
Thu 9/177:54 pm -
2 stops37h 30m
Deal found 8/8![Multiple Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:40 am -
1 stop5h 50m
Tue 9/152:25 pm -
1 stop5h 35m
Deal found 8/11![Delta logo]()
$560
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:27 pm -
Nonstop2h 28m
Tue 9/1512:30 pm -
Nonstop2h 19m
Deal found 8/11![American Airlines logo]()
$561
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:59 am -
1 stop7h 22m
Tue 9/1512:05 pm -
2 stops21h 19m
Deal found 8/11![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:59 pm -
1 stop23h 32m
Mon 9/284:57 pm -
2 stops40h 27m
Deal found 8/7![Breeze Airways logo]()
$418
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:47 pm -
1 stop3h 56m
Mon 9/2810:27 am -
1 stop4h 22m
Deal found 8/7![American Airlines logo]()
$437
One-way flights from Key West to South CarolinaSearch for one-way flight options from Key West to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
Search for one-way flight options from Key West to South Carolina. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:07 pm -
1 stop19h 54m
Deal found 8/7![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:59 am -
1 stop7h 22m
Deal found 8/10![Multiple Airlines logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:59 am -
1 stop7h 22m
Deal found 8/10![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:59 am -
1 stop21h 36m
Deal found 8/7![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:59 am -
1 stop5h 39m
Deal found 8/7![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:59 am -
1 stop5h 39m
Deal found 8/11![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:59 am -
1 stop25h 39m
Deal found 8/11![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:59 am -
1 stop21h 36m
Deal found 8/7![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:04 am -
1 stop3h 20m
Deal found 8/9![Breeze Airways logo]()
$163
This Breeze Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:59 am -
1 stop21h 39m
Deal found 8/10![Breeze Airways logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:04 am -
3 stops22h 34m
Deal found 8/9![Multiple Airlines logo]()
$232
This Breeze Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:59 am -
1 stop21h 49m
Deal found 8/10![Breeze Airways logo]()
$256
Find flight deals from Key West to South Carolina
Keep the following information in mind while searching for Key West to South Carolina flight deals. Data was last updated August 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $180 (Breeze Airways) |
One-way from | $104 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from Key West to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Fri 9/4
12:07 pm-8:48 am
1 stop20h 41m
Charleston
Fri 9/11
8:58 pm-9:24 am
1 stop12h 26m
$180
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Thu 10/22
12:01 pm-1:50 pm
1 stop25h 49m
Charleston
Sat 10/24
6:00 am-9:24 am
1 stop3h 24m
$273
Key WestCharlotte
EYW Key West - CLT Charlotte Douglas
EYWCLT
Key West
Mon 8/31
12:07 pm-8:01 am
1 stop19h 54m
Charlotte Douglas
Mon 9/21
10:56 am-9:24 am
2 stops46h 28m
$279
Key WestCharlotte
EYW Key West - CLT Charlotte Douglas
EYWCLT
Key West
Thu 9/10
10:59 am-6:21 pm
1 stop7h 22m
Charlotte Douglas
Thu 9/17
9:32 am-10:19 am
1 stop24h 47m
$288
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Fri 10/9
10:20 pm-8:38 am
1 stop10h 18m
Charleston
Sun 10/11
6:45 am-7:51 pm
1 stop13h 06m
$320
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Fri 10/23
10:59 am-8:38 am
1 stop21h 39m
Charleston
Sun 10/25
2:13 pm-10:19 am
1 stop20h 06m
$325
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Fri 10/9
10:59 am-8:38 am
1 stop21h 39m
Charleston
Sun 10/11
10:05 pm-12:19 pm
2 stops14h 14m
$358
Key WestCharlotte
EYW Key West - CLT Charlotte Douglas
EYWCLT
Key West
Thu 12/3
10:59 am-8:44 pm
1 stop9h 45m
Charlotte Douglas
Mon 12/7
9:39 pm-10:19 am
1 stop12h 40m
$388
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Mon 9/21
12:59 pm-12:31 pm
1 stop23h 32m
Charleston
Mon 9/28
4:57 pm-9:24 am
2 stops40h 27m
$418
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Mon 9/21
7:47 pm-11:43 pm
1 stop3h 56m
Charleston
Mon 9/28
10:27 am-2:49 pm
1 stop4h 22m
$437
Showing 1-10 of 39 resultsSorted by cheapest first
Best time to book a flight from Key West to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Key West with our price prediction graph.
EYW-CHS
EYW-CLT
EYW-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Key West to South Carolina
EYW-USSC
EYW-CHS
EYW-CLT
EYW-SAV
No data available for this route at this time. Please check back soon.
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