$74+ Cheap flights from Key West (EYW) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Oct 30 — Nov 61
Round-trip
1 adult, Economy
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Find cheap flights from Key West to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to South Carolina
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Cheapest flights from Key West to South CarolinaExplore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:59 am -
1 stop21h 39m
Wed 10/146:00 am -
1 stop3h 24m
Deal found 9/28![Breeze Airways logo]()
$160
This Expedia deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:16 pm -
1 stop24h 08m
Sat 10/173:42 pm -
1 stop18h 37m
Deal found 9/28![Breeze Airways logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:59 am -
1 stop21h 39m
Wed 9/306:00 am -
1 stop3h 24m
Deal found 9/27![Breeze Airways logo]()
$246
This Expedia deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:16 pm -
1 stop24h 08m
Wed 10/143:42 pm -
1 stop18h 37m
Deal found 9/28![Breeze Airways logo]()
$292
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:53 pm -
1 stop7h 01m
Tue 12/812:21 pm -
1 stop5h 00m
Deal found 9/28![American Airlines logo]()
$336
This Breeze Airways deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:59 am -
1 stop4h 48m
Mon 10/57:08 pm -
1 stop17h 28m
Deal found 9/25![Breeze Airways logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:59 am -
1 stop21h 49m
Fri 10/28:58 pm -
1 stop12h 26m
Deal found 9/28![Breeze Airways logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:59 am -
1 stop21h 49m
Tue 10/131:21 pm -
1 stop20h 03m
Deal found 9/28![Breeze Airways logo]()
$409
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:11 pm -
1 stop5h 36m
Wed 10/147:00 am -
1 stop3h 47m
Deal found 9/25![Delta logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:59 am -
1 stop21h 49m
Tue 10/137:00 am -
2 stops26h 24m
Deal found 9/28![Multiple Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:47 pm -
1 stop5h 24m
Mon 10/58:00 am -
1 stop5h 03m
Deal found 9/28![American Airlines logo]()
$496
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:59 am -
2 stops20h 39m
Wed 9/306:00 am -
1 stop3h 24m
Deal found 9/27![Multiple Airlines logo]()
$514
Best flights from Key West to South CarolinaDiscover carefully curated flight deals from Key West to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from Key West to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This Breeze Airways deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2110:59 am -
1 stop20h 59m
Sun 1/242:13 pm -
1 stop20h 06m
Deal found 9/28![Breeze Airways logo]()
$197
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:53 pm -
1 stop5h 10m
Tue 12/88:07 am -
2 stops9h 12m
Deal found 9/28![American Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:16 pm -
2 stops45h 47m
Sat 10/176:00 am -
1 stop3h 24m
Deal found 9/28![Breeze Airways logo]()
$361
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:15 am -
1 stop6h 50m
Mon 12/286:03 am -
1 stop4h 50m
Deal found 9/25![Delta logo]()
$759
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/201:35 pm -
1 stop5h 32m
Mon 12/287:42 pm -
1 stop16h 25m
Deal found 9/26![United Airlines logo]()
$766
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:59 am -
1 stop21h 49m
Tue 10/131:21 pm -
1 stop20h 03m
Deal found 9/28![Breeze Airways logo]()
$409
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:19 pm -
1 stop4h 37m
Wed 10/148:53 am -
2 stops8h 05m
Deal found 9/25![American Airlines logo]()
$561
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:51 am -
1 stop5h 23m
Fri 10/163:53 pm -
1 stop4h 08m
Deal found 9/27![Delta logo]()
$765
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/73:04 pm -
2 stops27h 55m
Sun 1/102:30 pm -
2 stops23h 38m
Deal found 9/29![United Airlines logo]()
$870
This KAYAK deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:01 pm -
2 stops20h 02m
Tue 12/84:03 pm -
3 stops43h 18m
Deal found 9/25![Breeze Airways logo]()
$854
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:19 pm -
1 stop4h 37m
Fri 10/168:53 am -
2 stops10h 40m
Deal found 9/27![American Airlines logo]()
$991
Last-minute flights from Key West to South CarolinaDiscover last-minute flight deals from Key West to South Carolina. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to South Carolina. Data last updated September 30, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:59 am -
1 stop21h 49m
Fri 10/28:58 pm -
1 stop12h 26m
Deal found 9/28![Breeze Airways logo]()
$391
This Breeze Airways deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:59 am -
1 stop4h 48m
Mon 10/57:08 pm -
1 stop17h 28m
Deal found 9/25![Breeze Airways logo]()
$379
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:47 pm -
1 stop5h 24m
Mon 10/58:00 am -
1 stop5h 03m
Deal found 9/28![American Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:11 pm -
1 stop5h 36m
Wed 10/147:00 am -
1 stop3h 47m
Deal found 9/25![Delta logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:19 pm -
1 stop4h 37m
Wed 10/148:53 am -
2 stops8h 05m
Deal found 9/25![American Airlines logo]()
$561
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:59 am -
1 stop21h 49m
Tue 10/131:21 pm -
1 stop20h 03m
Deal found 9/28![Breeze Airways logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:59 am -
1 stop21h 49m
Tue 10/137:00 am -
2 stops26h 24m
Deal found 9/28![Multiple Airlines logo]()
$444
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:59 am -
1 stop21h 39m
Wed 10/146:00 am -
1 stop3h 24m
Deal found 9/28![Breeze Airways logo]()
$160
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:51 am -
1 stop5h 23m
Fri 10/163:53 pm -
1 stop4h 08m
Deal found 9/27![Delta logo]()
$765
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:19 pm -
1 stop4h 37m
Fri 10/168:53 am -
2 stops10h 40m
Deal found 9/27![American Airlines logo]()
$991
This Expedia deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:16 pm -
1 stop24h 08m
Sat 10/173:42 pm -
1 stop18h 37m
Deal found 9/28![Breeze Airways logo]()
$245
This Expedia deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:16 pm -
1 stop24h 08m
Wed 10/143:42 pm -
1 stop18h 37m
Deal found 9/28![Breeze Airways logo]()
$292
One-way flights from Key West to South CarolinaSearch for one-way flight options from Key West to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from Key West to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:04 am -
1 stop9h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Breeze Airways logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:16 pm -
1 stop24h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Breeze Airways logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:04 am -
1 stop3h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:35 pm -
1 stop15h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Breeze Airways logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:59 pm -
1 stop7h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Breeze Airways logo]()
$81
This Expedia deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:59 am -
1 stop9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Breeze Airways logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:16 pm -
1 stop24h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1912:59 pm -
1 stop7h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Breeze Airways logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:59 am -
1 stop21h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:04 am -
1 stop3h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Breeze Airways logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:54 pm -
1 stop23h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:16 pm -
1 stop22h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Breeze Airways logo]()
$125
Find flight deals from Key West to South Carolina
Keep the following information in mind while searching for Key West to South Carolina flight deals. Data was last updated September 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $160 (Kiwi.com) |
One-way from | $74 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from Key West to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Key WestGreenville
EYW Key West - GSP Greenville
EYWGSP
Key West
Wed 10/21
10:04 am-7:44 pm
1 stop9h 40m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$74
Key WestGreenville
EYW Key West - GSP Greenville
EYWGSP
Key West
Fri 2/19
12:59 pm-8:17 pm
1 stop7h 18m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$103
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Mon 10/19
2:54 pm-2:38 pm
1 stop23h 44m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$121
Key WestMyrtle Beach
EYW Key West - MYR Myrtle Beach Intl
EYWMYR
Key West
Tue 10/27
1:16 pm-11:44 am
1 stop22h 28m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$125
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Thu 10/15
10:59 am-8:48 am
1 stop21h 49m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$126
Key WestGreenville
EYW Key West - GSP Greenville
EYWGSP
Key West
Thu 11/5
12:01 pm-8:15 am
2 stops20h 14m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$127
Key WestMyrtle Beach
EYW Key West - MYR Myrtle Beach Intl
EYWMYR
Key West
Tue 10/27
1:16 pm-8:51 am
3 stops43h 35m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$130
Key WestGreenville
EYW Key West - GSP Greenville
EYWGSP
Key West
Mon 12/21
12:59 pm-8:12 pm
1 stop7h 13m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$132
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Tue 10/13
1:16 pm-1:24 pm
1 stop24h 08m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Fri 2/19
12:59 pm-5:06 pm
1 stop4h 07m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$154
Showing 1-10 of 41 resultsSorted by cheapest first
Best time to book a flight from Key West to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Key West with our price prediction graph.
EYW-CHS
EYW-MYR
EYW-CAE
EYW-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Key West to South Carolina
EYW-USSC
EYW-CHS
EYW-MYR
EYW-CAE
EYW-GSP
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