$83+ Cheap flights from Key West (EYW) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Dec 10 — Dec 171
Round-trip
1 adult, Economy
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Find cheap flights from Key West to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to South Carolina
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Cheapest flights from Key West to South CarolinaExplore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:04 am -
1 stop10h 03m
Mon 11/238:32 pm -
1 stop13h 52m
Deal found 11/7![Breeze Airways logo]()
$151
This Expedia deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:04 am -
1 stop21h 39m
Sat 11/286:00 am -
1 stop3h 24m
Deal found 11/9![Breeze Airways logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:59 am -
1 stop4h 48m
Tue 12/2210:18 am -
1 stop27h 29m
Deal found 11/7![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:04 am -
1 stop10h 03m
Wed 11/252:33 pm -
1 stop25h 36m
Deal found 11/5![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:59 am -
1 stop4h 48m
Tue 12/229:12 am -
2 stops31h 43m
Deal found 11/7![Breeze Airways logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:04 am -
1 stop10h 03m
Wed 11/255:05 pm -
2 stops42h 14m
Deal found 11/5![Breeze Airways logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:01 pm -
2 stops20h 02m
Thu 11/262:46 pm -
1 stop19h 33m
Deal found 11/6![Breeze Airways logo]()
$363
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:57 pm -
1 stop4h 58m
Sat 11/285:30 am -
1 stop4h 23m
Deal found 11/9![American Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:20 pm -
2 stops28h 15m
Sat 11/286:00 am -
1 stop3h 24m
Deal found 11/9![Multiple Airlines logo]()
$433
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:30 am -
1 stop5h 44m
Fri 11/276:00 am -
1 stop4h 48m
Deal found 11/8![Delta logo]()
$589
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:15 am -
2 stops9h 48m
Tue 12/229:43 am -
2 stops7h 43m
Deal found 11/7![American Airlines logo]()
$662
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:43 pm -
2 stops7h 12m
Sat 11/285:05 am -
2 stops8h 02m
Deal found 11/9![American Airlines logo]()
$687
Best flights from Key West to South CarolinaDiscover carefully curated flight deals from Key West to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from Key West to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Expedia deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:04 am -
1 stop21h 39m
Sat 11/286:00 am -
1 stop3h 24m
Deal found 11/9![Breeze Airways logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:59 am -
1 stop4h 48m
Tue 12/2210:18 am -
1 stop27h 29m
Deal found 11/7![Multiple Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:22 am -
2 stops9h 32m
Sat 11/285:30 am -
1 stop5h 25m
Deal found 11/9![American Airlines logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:04 am -
1 stop10h 03m
Wed 11/252:33 pm -
1 stop25h 36m
Deal found 11/5![Multiple Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:30 am -
1 stop5h 44m
Fri 11/276:00 am -
1 stop4h 48m
Deal found 11/8![Delta logo]()
$589
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:59 am -
1 stop4h 48m
Tue 12/229:12 am -
2 stops31h 43m
Deal found 11/7![Breeze Airways logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:04 am -
1 stop10h 03m
Wed 11/255:05 pm -
2 stops42h 14m
Deal found 11/5![Breeze Airways logo]()
$346
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/201:35 pm -
1 stop5h 32m
Mon 12/287:42 pm -
2 stops20h 16m
Deal found 11/8![United Airlines logo]()
$841
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:01 pm -
2 stops20h 02m
Thu 11/262:46 pm -
1 stop19h 33m
Deal found 11/6![Breeze Airways logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:20 pm -
2 stops28h 15m
Sat 11/286:00 am -
1 stop3h 24m
Deal found 11/9![Multiple Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:15 am -
2 stops9h 48m
Tue 12/229:43 am -
2 stops7h 43m
Deal found 11/7![American Airlines logo]()
$662
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1910:59 am -
1 stop21h 46m
Fri 3/266:17 pm -
1 stop17h 25m
Deal found 11/8![Breeze Airways logo]()
$512
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:15 am -
1 stop4h 59m
Mon 12/282:46 pm -
1 stop6h 11m
Deal found 11/10![Delta logo]()
$743
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:43 pm -
2 stops7h 12m
Sat 11/285:05 am -
2 stops8h 02m
Deal found 11/9![American Airlines logo]()
$687
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:50 pm -
1 stop18h 22m
Mon 11/233:35 pm -
1 stop22h 17m
Deal found 11/6![United Airlines logo]()
$897
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/201:23 pm -
1 stop4h 51m
Mon 12/286:51 am -
2 stops10h 35m
Deal found 11/6![American Airlines logo]()
$816
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:50 pm -
2 stops23h 38m
Wed 11/257:00 am -
1 stop27h 28m
Deal found 11/6![United Airlines logo]()
$1,032
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:25 am -
2 stops10h 40m
Fri 11/278:54 am -
2 stops9h 59m
Deal found 11/8![American Airlines logo]()
$931
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:50 pm -
2 stops28h 11m
Sat 11/287:43 pm -
2 stops18h 12m
Deal found 11/9![United Airlines logo]()
$1,131
Last-minute flights from Key West to South CarolinaDiscover last-minute flight deals from Key West to South Carolina. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to South Carolina. Data last updated November 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:04 am -
1 stop10h 03m
Mon 11/238:32 pm -
1 stop13h 52m
Deal found 11/7![Breeze Airways logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:04 am -
1 stop10h 03m
Wed 11/252:33 pm -
1 stop25h 36m
Deal found 11/5![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:04 am -
1 stop10h 03m
Wed 11/255:05 pm -
2 stops42h 14m
Deal found 11/5![Breeze Airways logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:01 pm -
2 stops20h 02m
Thu 11/262:46 pm -
1 stop19h 33m
Deal found 11/6![Breeze Airways logo]()
$363
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:30 am -
1 stop5h 44m
Fri 11/276:00 am -
1 stop4h 48m
Deal found 11/8![Delta logo]()
$589
This Expedia deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:04 am -
1 stop21h 39m
Sat 11/286:00 am -
1 stop3h 24m
Deal found 11/9![Breeze Airways logo]()
$232
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:57 pm -
1 stop4h 58m
Sat 11/285:30 am -
1 stop4h 23m
Deal found 11/9![American Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:20 pm -
2 stops28h 15m
Sat 11/286:00 am -
1 stop3h 24m
Deal found 11/9![Multiple Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:43 pm -
2 stops7h 12m
Sat 11/285:05 am -
2 stops8h 02m
Deal found 11/9![American Airlines logo]()
$687
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:59 am -
1 stop4h 48m
Tue 12/2210:18 am -
1 stop27h 29m
Deal found 11/7![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:59 am -
1 stop4h 48m
Tue 12/229:12 am -
2 stops31h 43m
Deal found 11/7![Breeze Airways logo]()
$330
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:15 am -
2 stops9h 48m
Tue 12/229:43 am -
2 stops7h 43m
Deal found 11/7![American Airlines logo]()
$662
One-way flights from Key West to South CarolinaSearch for one-way flight options from Key West to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
Search for one-way flight options from Key West to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
This Breeze Airways deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3012:59 pm -
1 stop26h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Breeze Airways logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:59 am -
1 stop21h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Breeze Airways logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:04 am -
1 stop9h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Breeze Airways logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:59 am -
1 stop21h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Breeze Airways logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1410:59 am -
1 stop23h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Breeze Airways logo]()
$149
This Breeze Airways deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:59 am -
1 stop21h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Breeze Airways logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:59 am -
3 stops49h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$165
This Breeze Airways deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2012:19 pm -
1 stop21h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Breeze Airways logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:20 pm -
1 stop20h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Allegiant Air logo]()
$182
This Breeze Airways deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1012:22 pm -
1 stop21h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Breeze Airways logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1311:01 am -
2 stops46h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$195
This Breeze Airways deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:59 am -
1 stop21h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Breeze Airways logo]()
$209
Find flight deals from Key West to South Carolina
Keep the following information in mind while searching for Key West to South Carolina flight deals. Data was last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $232 (Expedia) |
One-way from | $83 (Breeze Airways) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from Key West to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Key WestGreenville
EYW Key West - GSP Greenville
EYWGSP
Key West
Mon 11/30
12:59 pm-3:29 pm
1 stop26h 30m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$83
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Tue 11/24
11:04 am-8:43 am
1 stop21h 39m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Fri 11/27
10:59 am-8:43 am
1 stop21h 44m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
Key WestMyrtle Beach
EYW Key West - MYR Myrtle Beach Intl
EYWMYR
Key West
Mon 12/14
10:59 am-10:05 am
1 stop23h 06m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$149
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Sun 11/22
10:59 am-8:48 am
1 stop21h 49m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
Key WestGreenville
EYW Key West - GSP Greenville
EYWGSP
Key West
Sat 2/20
12:19 pm-9:32 am
1 stop21h 13m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Fri 11/20
12:59 pm-7:14 pm
2 stops30h 15m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$183
Key WestGreenville
EYW Key West - GSP Greenville
EYWGSP
Key West
Sat 4/10
12:22 pm-9:30 am
1 stop21h 08m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$189
Key WestMyrtle Beach
EYW Key West - MYR Myrtle Beach Intl
EYWMYR
Key West
Sun 12/13
11:01 am-9:55 am
2 stops46h 54m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$195
Key WestCharleston
EYW Key West - CHS Charleston
EYWCHS
Key West
Sun 12/6
10:59 am-8:48 am
1 stop21h 49m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
Showing 1-10 of 44 resultsSorted by cheapest first
Best time to book a flight from Key West to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Key West with our price prediction graph.
EYW-GSP
EYW-CHS
EYW-MYR
EYW-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Key West to South Carolina
EYW-USSC
EYW-GSP
EYW-CHS
EYW-MYR
EYW-CAE
No data available for this route at this time. Please check back soon.
Related info for your journey
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