$94+ Cheap flights from Key West (EYW) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Jun 2 — Jun 91
Round-trip
1 adult, Economy
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Find cheap flights from Key West to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Key West to South CarolinaExplore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
Explore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
This Breeze Airways deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:07 pm
EYW
- CHS
1 stop20h 41m
Breeze Airways
Wed 5/134:34 pm
CHS
- EYW
1 stop18h 51m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$186
This Breeze Airways deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:07 pm
EYW
- CHS
1 stop20h 41m
Breeze Airways
Mon 5/119:28 pm
CHS
- EYW
1 stop15h 06m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:07 pm
EYW
- CLT
1 stop6h 45m
Multiple Airlines
Sun 6/77:57 pm
CLT
- EYW
1 stop18h 38m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:05 pm
EYW
- CLT
1 stop6h 47m
Multiple Airlines
Sun 5/107:57 pm
CLT
- EYW
1 stop15h 30m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:05 pm
EYW
- CHS
1 stop4h 06m
Breeze Airways
Mon 5/189:28 pm
CHS
- EYW
1 stop15h 06m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:07 pm
EYW
- CLT
1 stop23h 58m
Multiple Airlines
Tue 5/193:16 pm
CLT
- EYW
2 stops19h 50m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:07 pm
EYW
- CLT
1 stop6h 45m
Multiple Airlines
Mon 6/19:07 pm
CLT
- EYW
2 stops37h 59m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:34 pm
EYW
- SAV
1 stop24h 21m
Allegiant Air
Mon 5/187:30 am
SAV
- EYW
1 stop9h 28m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:11 pm
EYW
- CHS
1 stop20h 26m
Multiple Airlines
Fri 6/59:25 pm
CHS
- EYW
2 stops39h 51m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:58 am
EYW
- CHS
2 stops34h 55m
Multiple Airlines
Mon 5/189:28 pm
CHS
- EYW
1 stop15h 06m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:04 am
EYW
- SAV
2 stops10h 10m
Multiple Airlines
Mon 5/187:30 am
SAV
- EYW
1 stop9h 28m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:05 pm
EYW
- CLT
1 stop23h 29m
Multiple Airlines
Thu 6/181:09 pm
CLT
- EYW
2 stops22h 18m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$357
Best flights from Key West to South CarolinaDiscover carefully curated flight deals from Key West to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
Discover carefully curated flight deals from Key West to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:34 pm
EYW
- SAV
1 stop24h 21m
Allegiant Air
Mon 5/187:30 am
SAV
- EYW
1 stop9h 28m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:11 pm
EYW
- CHS
1 stop20h 26m
Multiple Airlines
Fri 6/59:25 pm
CHS
- EYW
2 stops39h 51m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:35 pm
EYW
- SAV
1 stop4h 14m
Delta
Fri 9/2510:20 am
SAV
- EYW
1 stop6h 54m
Delta
Deal found 4/29![Delta logo]()
$427
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:24 am
EYW
- SAV
2 stops10h 21m
American Airlines
Mon 5/185:00 am
SAV
- EYW
2 stops5h 54m
American Airlines
Deal found 4/29![American Airlines logo]()
$497
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:58 am
EYW
- CHS
2 stops34h 55m
Multiple Airlines
Mon 5/189:28 pm
CHS
- EYW
1 stop15h 06m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$317
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:49 pm
EYW
- CLT
2 stops28h 06m
United Airlines
Sun 5/176:15 am
CLT
- EYW
1 stop8h 52m
United Airlines
Deal found 4/29![United Airlines logo]()
$691
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/53:25 pm
EYW
- CLT
1 stop20h 40m
Multiple Airlines
Sun 6/71:00 pm
CLT
- EYW
2 stops19h 11m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$354
This Gotogate deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:04 am
EYW
- CHS
2 stops9h 45m
Breeze Airways
Mon 5/184:57 pm
CHS
- EYW
3 stops19h 37m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$871
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2212:18 pm
EYW
- CLT
1 stop18h 08m
American Airlines
Fri 7/318:49 pm
CLT
- EYW
1 stop14h 40m
American Airlines
Deal found 4/29![American Airlines logo]()
$538
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:28 am
EYW
- CLT
1 stop6h 49m
American Airlines
Sun 6/74:31 pm
CLT
- EYW
Nonstop2h 18m
American Airlines
Deal found 4/30![American Airlines logo]()
$545
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/181:22 pm
EYW
- CLT
1 stop4h 54m
Delta
Mon 6/18:01 am
CLT
- EYW
1 stop4h 59m
Delta
Deal found 5/2![Delta logo]()
$600
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:04 pm
EYW
- CLT
1 stop9h 30m
American Airlines
Mon 6/110:29 pm
CLT
- EYW
1 stop13h 11m
American Airlines
Deal found 4/29![American Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:49 pm
EYW
- CLT
1 stop6h 20m
United Airlines
Mon 5/187:00 am
CLT
- EYW
2 stops32h 07m
United Airlines
Deal found 5/2![United Airlines logo]()
$746
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:58 pm
EYW
- CHS
2 stops8h 01m
American Airlines
Mon 5/185:00 am
CHS
- EYW
2 stops5h 54m
American Airlines
Deal found 4/29![American Airlines logo]()
$569
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:40 pm
EYW
- SAV
2 stops9h 31m
American Airlines
Fri 8/287:26 pm
SAV
- EYW
1 stop16h 10m
American Airlines
Deal found 5/3![American Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:00 pm
EYW
- SAV
2 stops31h 52m
United Airlines
Sun 7/511:30 am
SAV
- EYW
1 stop27h 49m
United Airlines
Deal found 4/30![United Airlines logo]()
$841
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:59 pm
EYW
- SAV
2 stops9h 37m
American Airlines
Fri 9/255:24 am
SAV
- EYW
2 stops7h 33m
American Airlines
Deal found 4/29![American Airlines logo]()
$579
This Gotogate deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:07 am
EYW
- CHS
2 stops6h 53m
Breeze Airways
Fri 6/510:46 am
CHS
- EYW
3 stops48h 39m
Breeze Airways
Deal found 5/3![Breeze Airways logo]()
$957
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:26 pm
EYW
- CHS
2 stops19h 50m
United Airlines
Fri 6/57:47 pm
CHS
- EYW
2 stops17h 43m
United Airlines
Deal found 5/3![United Airlines logo]()
$845
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:20 pm
EYW
- SAV
2 stops20h 34m
United Airlines
Fri 8/287:15 pm
SAV
- EYW
3 stops26h 56m
United Airlines
Deal found 5/3![United Airlines logo]()
$981
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:20 pm
EYW
- CHS
1 stop24h 34m
United Airlines
Mon 8/2411:08 am
CHS
- EYW
1 stop26h 26m
United Airlines
Deal found 4/29![United Airlines logo]()
$1,169
Last-minute flights from Key West to South CarolinaDiscover last-minute flight deals from Key West to South Carolina. Data last updated May 3, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to South Carolina. Data last updated May 3, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:33 am
EYW
- SAV
1 stop6h 49m
Delta
Wed 5/68:11 am
SAV
- EYW
1 stop5h 33m
Delta
Deal found 4/30![Delta logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:05 pm
EYW
- CLT
1 stop6h 47m
Multiple Airlines
Sun 5/107:57 pm
CLT
- EYW
1 stop15h 30m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$217
This Breeze Airways deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:07 pm
EYW
- CHS
1 stop20h 41m
Breeze Airways
Wed 5/134:34 pm
CHS
- EYW
1 stop18h 51m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$186
This Breeze Airways deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:07 pm
EYW
- CHS
1 stop20h 41m
Breeze Airways
Mon 5/119:28 pm
CHS
- EYW
1 stop15h 06m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:05 pm
EYW
- CHS
1 stop4h 06m
Breeze Airways
Mon 5/189:28 pm
CHS
- EYW
1 stop15h 06m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:34 pm
EYW
- SAV
1 stop24h 21m
Allegiant Air
Mon 5/187:30 am
SAV
- EYW
1 stop9h 28m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:58 am
EYW
- CHS
2 stops34h 55m
Multiple Airlines
Mon 5/189:28 pm
CHS
- EYW
1 stop15h 06m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:04 am
EYW
- SAV
2 stops10h 10m
Multiple Airlines
Mon 5/187:30 am
SAV
- EYW
1 stop9h 28m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:07 pm
EYW
- CLT
1 stop23h 58m
Multiple Airlines
Tue 5/193:16 pm
CLT
- EYW
2 stops19h 50m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:05 pm
EYW
- CLT
1 stop24h 00m
Multiple Airlines
Tue 6/21:00 pm
CLT
- EYW
2 stops22h 06m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:07 pm
EYW
- CLT
1 stop6h 45m
Multiple Airlines
Mon 6/19:07 pm
CLT
- EYW
2 stops37h 59m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$244
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:18 pm
EYW
- CLT
1 stop18h 04m
American Airlines
Mon 6/18:28 pm
CLT
- EYW
1 stop15h 12m
American Airlines
Deal found 4/29![American Airlines logo]()
$491
One-way flights from Key West to South CarolinaSearch for one-way flight options from Key West to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
Search for one-way flight options from Key West to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:07 pm
EYW
- CHS
1 stop20h 41m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:05 pm
EYW
- CHS
1 stop20h 40m
Breeze Airways
Deal found 5/1![Breeze Airways logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2612:07 pm
EYW
- CLT
1 stop20h 41m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:07 pm
EYW
- CLT
1 stop28h 36m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:05 pm
EYW
- CLT
1 stop6h 47m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2412:05 pm
EYW
- CLT
1 stop6h 47m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:59 am
EYW
- CLT
1 stop8h 35m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:46 am
EYW
- CLT
2 stops23h 48m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2712:07 pm
EYW
- CLT
1 stop28h 28m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:59 am
EYW
- CLT
1 stop8h 35m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/231:14 pm
EYW
- CLT
2 stops23h 00m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:59 am
EYW
- CLT
1 stop8h 35m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$146
Find flight deals from Key West to South Carolina
Keep the following information in mind while searching for Key West to South Carolina flight deals. Data was last updated May 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $208 (Kiwi.com) |
One-way from | $94 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Key West to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Key WestSavannah
EYW - SAV
EYWSAV
Key West
Thu 5/14
12:34 pm-12:55 pm
1 stop24h 21m
Savannah/Hilton Head
Mon 5/18
7:30 am-4:58 pm
1 stop9h 28m
$279
Key WestCharleston
EYW - CHS
EYWCHS
Key West
Mon 6/1
1:11 pm-9:37 am
1 stop20h 26m
Charleston
Fri 6/5
9:25 pm-1:16 pm
2 stops39h 51m
$303
Key WestCharleston
EYW - CHS
EYWCHS
Key West
Thu 5/14
9:58 am-8:53 pm
2 stops34h 55m
Charleston
Mon 5/18
9:28 pm-12:34 pm
1 stop15h 06m
$317
Key WestCharlotte
EYW - CLT
EYWCLT
Key West
Fri 6/5
3:25 pm-12:05 pm
1 stop20h 40m
Charlotte Douglas
Sun 6/7
1:00 pm-8:11 am
2 stops19h 11m
$354
Key WestSavannah
EYW - SAV
EYWSAV
Key West
Fri 9/18
2:35 pm-6:49 pm
1 stop4h 14m
Savannah/Hilton Head
Fri 9/25
10:20 am-5:14 pm
1 stop6h 54m
$427
Key WestSavannah
EYW - SAV
EYWSAV
Key West
Thu 5/14
11:24 am-9:45 pm
2 stops10h 21m
Savannah/Hilton Head
Mon 5/18
5:00 am-10:54 am
2 stops5h 54m
$497
Key WestCharlotte
EYW - CLT
EYWCLT
Key West
Wed 7/22
12:18 pm-6:26 am
1 stop18h 08m
Charlotte Douglas
Fri 7/31
8:49 pm-11:29 am
1 stop14h 40m
$538
Quickest round-trip
Key WestCharlotte
EYW - CLT
EYWCLT
Key West
Fri 6/5
11:28 am-6:17 pm
1 stop6h 49m
Charlotte Douglas
Sun 6/7
4:31 pm-6:49 pm
Nonstop2h 18m
$545
Key WestCharlotte
EYW - CLT
EYWCLT
Key West
Mon 5/18
12:04 pm-9:34 pm
1 stop9h 30m
Charlotte Douglas
Mon 6/1
10:29 pm-11:40 am
1 stop13h 11m
$549
Key WestCharleston
EYW - CHS
EYWCHS
Key West
Thu 5/14
3:58 pm-11:59 pm
2 stops8h 01m
Charleston
Mon 5/18
5:00 am-10:54 am
2 stops5h 54m
$569
Showing 1-10 of 37 resultsSorted by cheapest first
Best time to book a flight from Key West to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Key West with our price prediction graph.
EYW-SAV
EYW-CHS
EYW-CLT
EYW-AGS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Key West to South Carolina
EYW-USSC
EYW-SAV
EYW-CHS
EYW-CLT
EYW-AGS
No data available for this route at this time. Please check back soon.
Related info for your journey
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