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$75+ Cheap flights from Des Moines to Jacksonville (DSM - JAX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAX
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Des Moines to Jacksonville are usually found in September or August, booked 86 days in advance, depart on a Thursday or Tuesday and return on a Thursday

Cheap flight deals from Des Moines to Jacksonville

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Jacksonville (JAX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$285
(Delta)

One-way from

$75
(Booking.com)

Popular in

March

Cheapest in

September

Average price

$367

Good round-trip deal

$90 or less

Good one-way deal

$49 or less
Provider with most accurate pricing for Des Moines-Jacksonville flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Jacksonville flights.
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From Des Moines to Jacksonville
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One-way flight from Des Moines to Jacksonville
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Des Moines to Jacksonville.
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Price to beat on a one-way flight from Des Moines to Jacksonville.
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Find flight deals from Des Moines to Jacksonville

Cheapest flights from Des Moines to Jacksonville
Explore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:45 amDSM - JAX
1 stop5h 36mAmerican Airlines
Wed 5/285:16 pmJAX - DSM
1 stop6h 40mAmerican Airlines
Deal found 4/27$285
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2811:26 amDSM - JAX
1 stop6h 43mDelta
Sat 6/75:37 pmJAX - DSM
1 stop5h 53mDelta
Deal found 4/26$301
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/96:30 pmDSM - JAX
1 stop3h 55mSouthwest
Sun 6/158:50 pmJAX - DSM
1 stop4h 15mSouthwest
Deal found 4/28$353
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/48:30 amDSM - JAX
2 stops27h 00mMultiple Airlines
Sun 5/117:40 pmJAX - DSM
2 stops28h 33mMultiple Airlines
Deal found 4/27$474
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/303:34 pmDSM - JAX
1 stop6h 54mUnited Airlines
Sat 5/34:22 pmJAX - DSM
1 stop8h 17mUnited Airlines
Deal found 4/28$663

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.

Fly from

Des Moines

Fly to

Jacksonville

Route

Depart

Return

Price

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Wed 5/21

6:45 am-1:21 pm

1 stop5h 36m

Jacksonville

Wed 5/28

5:16 pm-10:56 pm

1 stop6h 40m

$285

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Wed 5/28

11:26 am-7:09 pm

1 stop6h 43m

Jacksonville

Sat 6/7

5:37 pm-10:30 pm

1 stop5h 53m

$301

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Mon 6/9

6:30 pm-11:25 pm

1 stop3h 55m

Jacksonville

Sun 6/15

8:50 pm-12:05 am

1 stop4h 15m

$353

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sun 5/4

8:30 am-12:30 pm

2 stops27h 00m

Jacksonville

Sun 5/11

7:40 pm-11:13 pm

2 stops28h 33m

$474

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Fri 5/9

5:45 am-3:20 pm

1 stop8h 35m

Jacksonville

Sat 5/10

8:05 am-4:14 pm

1 stop9h 09m

$705

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Thu 5/22

8:30 am-12:07 pm

Nonstop2h 37m

$75

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Fri 5/30

4:04 pm-10:35 pm

1 stop5h 31m

$159

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Mon 5/26

6:25 am-8:07 pm

2 stops12h 42m

$205

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sun 5/18

6:00 am-11:05 am

1 stop4h 05m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Compare providers for flights from Des Moines to Jacksonville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Jacksonville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Jacksonville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Jacksonville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Jacksonville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Jacksonville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Jacksonville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Jacksonville

How far ahead should I book a flight from Des Moines to Jacksonville?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Jacksonville. Price data was last updated on April 25, 2025.

The price you pay for your flight from Des Moines to Jacksonville may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Jacksonville?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Jacksonville (average of $278). Flying from Des Moines to Jacksonville in March is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to JAX?

Find hourly flight availability from Des Moines to Jacksonville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

When flying from Des Moines to Jacksonville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 63% versus a flight in the afternoon.

Rainfall in Jacksonville by month

Plan your trip to Jacksonville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Jacksonville ranges from 2.1 - 8.2 inches per month. September is typically the wettest month, when rainfall can reach 8.2 in. November is typically the driest time to visit Jacksonville when rainfall is around 2.1 in.

Temperature in Jacksonville by month

Plan your trip to Jacksonville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Jacksonville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Jacksonville

Get insights into the airlines that provide service to Jacksonville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Jacksonville. Reviews last updated April 29, 2025.
Southwest
8.0
Very good
4,292 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,292 reviews
Southwest
8.0
Very good
4,292 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,929 reviews
Southwest
8.0
Very good
4,292 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,292 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Allegiant Air
7.3
Good
734 reviews
Southwest
8.0
Very good
4,292 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,292 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Jacksonville round-trip?

    Cheapflights users have booked flights from Des Moines to Jacksonville round-trip from $285. Other airlines that can offer you cheap pricing are American Airlines, from $295, and Southwest, from $332. These flights start at 25% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Jacksonville one-way?

    $75 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and Southwest, with prices starting from $159 and $294, respectively.

  • What are the cheapest flights from Des Moines to Jacksonville?

    The cheapest flight price from Des Moines to Jacksonville is $49. On average you can expect to pay $77. The most popular route, (Des Moines - Jacksonville), can usually be booked for $98.

  • Can I find deals for flights from Des Moines to Jacksonville that include hotel bookings?

    Yes. In addition to deals on Des Moines to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Jacksonville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Jacksonville.

  • Can I find deals for business class flights from Des Moines to Jacksonville?

    Yes. Cheapflights offers flight deals from Des Moines to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Jacksonville?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Jacksonville (average of $278). Flying from Des Moines to Jacksonville in March is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Jacksonville Beach
Kingsland
Orange Park
Waycross
Fernandina Beach

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Top 5 airlines flying from Des Moines to Jacksonville

Discover the top 5 airlines that operate flights from Des Moines to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$83Average$140FlexibilityNo cancel feeOn-time88%
DeltaCheapest$276Average$383FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$284Average$370FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$308Average$401FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$341Average$433FlexibilityNo cancel feeOn-time69%

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