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$119+ Cheap flights from Des Moines to Jacksonville (DSM - JAX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAX
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Des Moines to Jacksonville are usually found in October or August, booked 11 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Des Moines to Jacksonville

Cheapest flights from Des Moines to Jacksonville
Explore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:30 amDSM - JAX
1 stop8h 48mUnited Airlines
Thu 1/17:40 amJAX - DSM
1 stop7h 53mUnited Airlines
Deal found 12/16$312
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:00 pmDSM - JAX
1 stop7h 30mUnited Airlines
Thu 1/17:40 amJAX - DSM
1 stop7h 53mUnited Airlines
Deal found 12/16$357
This Southwest deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:15 pmDSM - JAX
1 stop3h 50mSouthwest
Sat 1/38:45 pmJAX - DSM
1 stop4h 10mSouthwest
Deal found 12/16$362
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:56 pmDSM - JAX
2 stops10h 03mAmerican Airlines
Thu 1/16:00 amJAX - DSM
1 stop5h 47mAmerican Airlines
Deal found 12/16$400
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:09 pmDSM - JAX
1 stop6h 12mAmerican Airlines
Sun 1/46:00 amJAX - DSM
1 stop5h 47mAmerican Airlines
Deal found 12/16$404
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:25 pmDSM - JAX
2 stops9h 34mAmerican Airlines
Sat 1/36:00 amJAX - DSM
2 stops6h 51mAmerican Airlines
Deal found 12/16$444
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:40 amDSM - JAX
2 stops9h 35mAmerican Airlines
Thu 1/16:00 amJAX - DSM
2 stops7h 54mAmerican Airlines
Deal found 12/16$446
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:27 pmDSM - JAX
2 stops7h 49mAmerican Airlines
Mon 1/56:05 pmJAX - DSM
1 stop7h 32mAmerican Airlines
Deal found 12/15$462

Find flight deals from Des Moines to Jacksonville

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Jacksonville (JAX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$197
(Kiwi.com)

One-way from

$119
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$406

Good one-way deal

$277 or less
Provider with most accurate pricing for Des Moines-Jacksonville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Jacksonville flights.
Search Deals
From Des Moines to Jacksonville
Search Deals
One-way flight from Des Moines to Jacksonville
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a one-way flight from Des Moines to Jacksonville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.

Fly from

Des Moines

Fly to

Jacksonville

Route

Depart

Return

Price

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Wed 1/7

5:16 pm-10:57 pm

1 stop4h 41m

Jacksonville

Sat 1/17

7:30 am-12:15 pm

1 stop5h 45m

$285

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Thu 12/25

5:30 am-3:18 pm

1 stop8h 48m

Jacksonville

Thu 1/1

7:40 am-2:33 pm

1 stop7h 53m

$312

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Sat 1/17

3:04 pm-9:47 pm

1 stop5h 43m

Jacksonville

Tue 1/20

2:40 pm-9:50 pm

1 stop8h 10m

$317

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Tue 2/17

3:24 pm-9:42 pm

1 stop5h 18m

Jacksonville

Tue 2/24

4:16 pm-11:43 pm

1 stop8h 27m

$333

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Tue 2/17

5:20 am-4:50 pm

2 stops10h 30m

Jacksonville

Tue 2/24

10:30 am-9:10 pm

2 stops11h 40m

$343

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Thu 1/8

6:00 am-3:41 pm

2 stops8h 41m

Jacksonville

Mon 1/12

4:41 pm-11:23 pm

1 stop7h 42m

$356

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Wed 12/24

3:00 pm-11:30 pm

1 stop7h 30m

Jacksonville

Thu 1/1

7:40 am-2:33 pm

1 stop7h 53m

$357

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Thu 1/15

6:00 am-1:49 pm

2 stops6h 49m

Jacksonville

Sun 1/18

6:00 am-12:46 pm

2 stops7h 46m

$359

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Wed 12/31

4:15 pm-9:05 pm

1 stop3h 50m

Jacksonville

Sat 1/3

8:45 pm-11:55 pm

1 stop4h 10m

$362

Des MoinesJacksonville

DSM - JAX

DSMJAX

Des Moines

Thu 12/25

5:30 am-3:18 pm

1 stop8h 48m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 17 results
1
2

Compare providers for flights from Des Moines to Jacksonville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Jacksonville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Jacksonville flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Jacksonville flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Jacksonville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Jacksonville flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Jacksonville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Jacksonville

How far ahead should I book a flight from Des Moines to Jacksonville?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Jacksonville. Price data was last updated on December 12, 2025.

The price you pay for your flight from Des Moines to Jacksonville may vary depending on when you book. For the best chance of a lower fare, look to book 11 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Jacksonville?

Currently, October is the cheapest month in which you can book a flight from Des Moines to Jacksonville (average of $42). Flying from Des Moines to Jacksonville in March is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to JAX?

Find hourly flight availability from Des Moines to Jacksonville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

When flying from Des Moines to Jacksonville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 77% versus a flight in the evening.

Reviews of airlines servicing Jacksonville

Get insights into the airlines that provide service to Jacksonville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Jacksonville. Reviews last updated December 18, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Des Moines to Jacksonville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,249 reviews

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,249 reviews
Southwest
7.9
Good
4,249 reviews

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,006 reviews
Southwest
7.9
Good
4,249 reviews

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,053 reviews
Southwest
7.9
Good
4,249 reviews

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Allegiant Air
7.2
Good
700 reviews
Southwest
7.9
Good
4,249 reviews

Comfort

8.0

Overall

7.9

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Des Moines to Jacksonville flight route?

    This flight path from Des Moines to Jacksonville was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Des Moines to Jacksonville?

    For as low as $285, Delta can have you in Jacksonville from Des Moines in 4h 41m. The distance between Des Moines and Jacksonville is about 1012 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Des Moines to Jacksonville round-trip?

    Cheapflights users have booked flights from Des Moines to Jacksonville round-trip from $62. Other airlines that can offer you cheap pricing are Delta, from $154, and American Airlines, from $216. These flights start at 76% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Jacksonville one-way?

    $38 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $154 and $158, respectively.

  • What are the cheapest flights from Des Moines to Jacksonville?

    The cheapest flight price from Des Moines to Jacksonville is $277. On average you can expect to pay $277. The most popular route, (Des Moines - Jacksonville), can usually be booked for $197.

  • Can I find deals for flights from Des Moines to Jacksonville that include hotel bookings?

    Yes. In addition to deals on Des Moines to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Jacksonville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Jacksonville.

  • Can I find deals for business class flights from Des Moines to Jacksonville?

    Yes. Cheapflights offers flight deals from Des Moines to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Jacksonville?

    Currently, October is the cheapest month in which you can book a flight from Des Moines to Jacksonville (average of $42). Flying from Des Moines to Jacksonville in March is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Jacksonville?

Book flights to Jacksonville if you plan to visit one of these locations
Jacksonville Beach
Orange Park
Fernandina Beach
Kingsland
Waycross

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Top 4 airlines flying from Des Moines to Jacksonville

Discover the top 4 airlines that operate flights from Des Moines to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$78Average$93FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$216Average$380FlexibilityNo cancel feeOn-time71%
DeltaCheapest$231Average$396FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$308Average$396FlexibilityNo cancel feeOn-time63%

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