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$49+ Cheap flights from Missouri to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Missouri to Iowa

Keep the following information in mind while searching for Missouri to Iowa flight deals. Data was last updated September 16, 2025.

Round-trip from

$119
(United Airlines)

One-way from

$49
(Southwest)

Good round-trip deal

$309 or less
From Missouri to Iowa
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One-way flight from Missouri to Iowa
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Price to beat on a round-trip flight from Missouri to Iowa.
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Find flight deals from Missouri to Iowa

Cheapest flights from Missouri to Iowa
Explore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/78:20 amSTL - DSM
Nonstop1h 10mSouthwest
Sat 10/113:50 pmDSM - STL
Nonstop1h 10mSouthwest
Deal found 9/16$97
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:00 amSTL - OMA
1 stop5h 31mUnited Airlines
Tue 10/148:00 amOMA - STL
1 stop6h 27mUnited Airlines
Deal found 9/14$119
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1010:20 pmSTL - DSM
Nonstop1h 10mSouthwest
Mon 10/135:35 amDSM - STL
Nonstop1h 10mSouthwest
Deal found 9/15$134
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:33 pmSTL - OMA
1 stop15h 15mFrontier
Mon 10/138:59 pmOMA - STL
1 stop12h 08mFrontier
Deal found 9/14$145
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/248:38 pmMCI - OMA
1 stop23h 26mFrontier
Sun 10/268:59 pmOMA - MCI
1 stop22h 54mFrontier
Deal found 9/14$153
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:16 amSTL - DSM
1 stop6h 02mAmerican Airlines
Sat 10/113:48 pmDSM - STL
1 stop5h 05mAmerican Airlines
Deal found 9/14$159
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:15 amSTL - OMA
1 stop7h 55mUnited Airlines
Wed 10/1511:27 amOMA - STL
1 stop4h 17mUnited Airlines
Deal found 9/14$179
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:00 amSTL - DSM
1 stop5h 32mUnited Airlines
Thu 10/166:30 amDSM - STL
1 stop4h 19mUnited Airlines
Deal found 9/15$179
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/107:52 pmSTL - OMA
1 stop24h 12mFrontier
Fri 10/178:59 pmOMA - STL
1 stop12h 08mFrontier
Deal found 9/14$186
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:52 pmSTL - OMA
1 stop24h 12mFrontier
Sun 10/128:59 pmOMA - STL
1 stop12h 08mFrontier
Deal found 9/14$202
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:52 pmSTL - OMA
1 stop24h 12mFrontier
Mon 10/138:59 pmOMA - STL
1 stop12h 08mFrontier
Deal found 9/14$207
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:45 pmSTL - DSM
Nonstop1h 10mSouthwest
Sat 11/17:25 amDSM - STL
1 stop5h 05mSouthwest
Deal found 9/15$223

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Missouri to Iowa that are best for you.

Fly from

Missouri

Fly to

Iowa

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 10/7

8:20 am-9:30 am

Nonstop1h 10m

Des Moines

Sat 10/11

3:50 pm-5:00 pm

Nonstop1h 10m

$97

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Thu 10/9

5:00 am-10:31 am

1 stop5h 31m

Omaha Eppley Airfield

Tue 10/14

8:00 am-2:27 pm

1 stop6h 27m

$119

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 10/10

10:20 pm-11:30 pm

Nonstop1h 10m

Des Moines

Mon 10/13

6:15 pm-7:25 pm

Nonstop1h 10m

$134

Kansas CityOmaha

MCI - OMA

MCIOMA

Kansas City

Fri 10/24

8:38 pm-8:04 pm

1 stop23h 26m

Omaha Eppley Airfield

Sun 10/26

8:59 pm-7:53 pm

1 stop22h 54m

$153

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 10/31

6:00 am-11:22 am

1 stop5h 22m

Des Moines

Sat 11/1

3:48 pm-8:53 pm

1 stop5h 05m

$159

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 10/7

8:42 am-1:18 pm

1 stop4h 36m

Des Moines

Sat 10/11

3:48 pm-8:53 pm

1 stop5h 05m

$159

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Sat 10/11

1:40 pm-7:56 pm

1 stop6h 16m

Omaha Eppley Airfield

Wed 10/15

11:27 am-3:44 pm

1 stop4h 17m

$179

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Wed 10/8

5:15 am-10:39 am

1 stop5h 24m

Omaha Eppley Airfield

Tue 10/14

8:00 am-2:27 pm

1 stop6h 27m

$179

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Wed 10/8

5:15 am-10:39 am

1 stop5h 24m

Omaha Eppley Airfield

Sat 10/11

3:06 pm-9:58 pm

1 stop6h 52m

$179

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Thu 10/9

5:00 am-10:31 am

1 stop5h 31m

Omaha Eppley Airfield

Sat 10/11

3:06 pm-9:58 pm

1 stop6h 52m

$179

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 56 results
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Best time to book a flight from Missouri to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Iowa

What is the cheapest month to book a flight from Missouri to Iowa?

Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IA?

Find hourly flight availability from Missouri to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Iowa as you normally would.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Missouri to Iowa, such as Southwest and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Missouri to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to Iowa flight route?

    The Missouri to Iowa flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Iowa?

    A quick flight from Missouri to Iowa can take about 1h 10m. Southwest provides one of the quickest options available for as low as $97. Missouri and Iowa are separated by a distance of 259 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Missouri to Iowa that include hotel bookings?

    Yes. In addition to deals on Missouri to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Iowa.

  • Can I find deals for business class flights from Missouri to Iowa?

    Yes. Cheapflights offers flight deals from Missouri to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Iowa?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Iowa

Discover the top 3 airlines that operate flights from Missouri to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Southern / MokuleleCheapest$52Average$89FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$97Average$309FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$142Average$282FlexibilityNo cancel feeOn-time71%

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