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$98+ Cheap flights from Missouri to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Missouri to Iowa

Keep the following information in mind while searching for Missouri to Iowa flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$230
(Booking.com)

One-way from

$98
(Mytrip)

Good round-trip deal

$203 or less

Good one-way deal

$65 or less
Provider with most accurate pricing for Kansas City-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Kansas City-Des Moines flights.
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From Missouri to Iowa
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One-way flight from Missouri to Iowa
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Price to beat on a round-trip flight from Missouri to Iowa.
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Price to beat on a one-way flight from Missouri to Iowa.
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Find flight deals from Missouri to Iowa

Cheapest flights from Missouri to Iowa
Explore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/307:24 pmSTL - OMA
1 stop23h 42mFrontier
Sun 6/87:51 pmOMA - STL
1 stop13h 21mFrontier
Deal found 4/30$230
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1810:05 pmSTL - DSM
Nonstop1h 10mSouthwest
Fri 6/205:25 amDSM - STL
Nonstop1h 05mSouthwest
Deal found 4/29$243
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/56:30 amSTL - DSM
1 stop3h 50mUnited Airlines
Sat 6/76:45 pmDSM - STL
1 stop4h 00mUnited Airlines
Deal found 4/30$247
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/36:32 amSGF - MLI
1 stop4h 22mAmerican Airlines
Sun 7/63:54 pmMLI - SGF
1 stop6h 18mAmerican Airlines
Deal found 4/30$259
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/59:50 amSTL - DSM
2 stops12h 47mMultiple Airlines
Sat 6/71:15 pmDSM - STL
2 stops29h 26mMultiple Airlines
Deal found 4/30$269
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/163:20 pmSGF - MLI
1 stop6h 15mUnited Airlines
Tue 5/205:25 pmMLI - SGF
1 stop4h 36mUnited Airlines
Deal found 5/1$274
This Mytrip deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:46 amMCI - OMA
1 stop27h 09mMultiple Airlines
Wed 6/41:32 pmOMA - MCI
2 stops29h 31mMultiple Airlines
Deal found 4/30$278
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/56:00 amSTL - DSM
1 stop4h 41mDelta
Sat 6/71:07 pmDSM - STL
2 stops8h 24mDelta
Deal found 4/30$283
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/74:32 pmSTL - OMA
1 stop7h 56mAmerican Airlines
Sun 8/102:19 pmOMA - STL
1 stop6h 00mAmerican Airlines
Deal found 4/29$286
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/283:21 pmMCI - MLI
1 stop6h 06mUnited Airlines
Wed 6/410:55 amMLI - MCI
1 stop3h 30mUnited Airlines
Deal found 4/30$286
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/305:40 pmMCI - DSM
1 stop4h 30mSouthwest
Fri 6/66:30 pmDSM - MCI
1 stop5h 15mSouthwest
Deal found 4/30$293
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2810:20 amMCI - OMA
1 stop5h 05mSouthwest
Wed 6/41:05 pmOMA - MCI
1 stop5h 55mSouthwest
Deal found 4/30$303

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Missouri to Iowa that are best for you.

Fly from

Missouri

Fly to

Iowa

Route

Depart

Return

Price

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Fri 5/30

7:24 pm-7:06 pm

1 stop23h 42m

Omaha Eppley Airfield

Sun 6/8

7:51 pm-9:12 am

1 stop13h 21m

$230

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 6/18

10:05 pm-11:15 pm

Nonstop1h 10m

Des Moines

Fri 6/20

5:25 am-6:30 am

Nonstop1h 05m

$243

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 6/5

6:30 am-10:20 am

1 stop3h 50m

Des Moines

Sat 6/7

6:45 pm-10:45 pm

1 stop4h 00m

$247

SpringfieldMoline

SGF - MLI

SGFMLI

Springfield-Branson

Thu 7/3

6:32 am-10:54 am

1 stop4h 22m

Moline Quad-City

Sun 7/6

3:54 pm-10:12 pm

1 stop6h 18m

$259

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 6/5

9:50 am-10:37 pm

2 stops12h 47m

Des Moines

Sat 6/7

1:15 pm-6:41 pm

2 stops29h 26m

$269

SpringfieldMoline

SGF - MLI

SGFMLI

Springfield-Branson

Fri 5/16

3:20 pm-9:35 pm

1 stop6h 15m

Moline Quad-City

Tue 5/20

5:25 pm-10:01 pm

1 stop4h 36m

$274

Kansas CityOmaha

MCI - OMA

MCIOMA

Kansas City

Wed 5/28

5:46 am-8:55 am

1 stop27h 09m

Omaha Eppley Airfield

Wed 6/4

1:32 pm-7:03 pm

2 stops29h 31m

$278

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 6/5

6:00 am-10:41 am

1 stop4h 41m

Des Moines

Sat 6/7

1:07 pm-9:31 pm

2 stops8h 24m

$283

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Thu 8/7

4:32 pm-12:28 am

1 stop7h 56m

Omaha Eppley Airfield

Sun 8/10

2:19 pm-8:19 pm

1 stop6h 00m

$286

Kansas CityMoline

MCI - MLI

MCIMLI

Kansas City

Wed 5/28

3:21 pm-9:27 pm

1 stop6h 06m

Moline Quad-City

Wed 6/4

10:55 am-2:25 pm

1 stop3h 30m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/1

Showing 1-10 of 40 results
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Best time to book a flight from Missouri to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Iowa

What is the cheapest month to book a flight from Missouri to Iowa?

Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IA?

Find hourly flight availability from Missouri to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Iowa as you normally would.

Rainfall in Iowa by month

Plan your trip to Iowa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Iowa ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Iowa when rainfall is around 1.0 in.

Temperature in Iowa by month

Plan your trip to Iowa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Iowa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated May 1, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Missouri to Iowa to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,972 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,972 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,293 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,934 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Entertainment

7.1

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to Iowa flight route?

    The Missouri to Iowa flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Missouri to Iowa one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $98. However, be on the lookout for offers from Southwest and Delta, as they are both options that can get you from Missouri to Iowa for a low price.

  • Can I find deals for flights from Missouri to Iowa that include hotel bookings?

    Yes. In addition to deals on Missouri to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Iowa.

  • Can I find deals for business class flights from Missouri to Iowa?

    Yes. Cheapflights offers flight deals from Missouri to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Iowa?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Iowa

Discover the top 3 airlines that operate flights from Missouri to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Southern / MokuleleCheapest$51Average$78FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$127Average$310FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$208Average$416FlexibilityNo cancel feeOn-time71%

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