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$49+ Cheap flights from Missouri to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Missouri to Iowa

Keep the following information in mind while searching for Missouri to Iowa flight deals. Data was last updated July 31, 2025.

Round-trip from

$97
(Southwest)

One-way from

$49
(Southwest)

Good round-trip deal

$381 or less
From Missouri to Iowa
Search Deals
One-way flight from Missouri to Iowa
Search Deals
Price to beat on a round-trip flight from Missouri to Iowa.
Search Deals

Find flight deals from Missouri to Iowa

Cheapest flights from Missouri to Iowa
Explore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/279:15 pmSTL - DSM
Nonstop1h 05mSouthwest
Wed 9/38:25 amDSM - STL
Nonstop1h 05mSouthwest
Deal found 7/30$97
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2710:15 amSTL - DSM
1 stop6h 07mDelta
Sat 10/412:32 pmDSM - STL
1 stop4h 10mDelta
Deal found 7/29$167
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/284:25 pmSTL - OMA
Nonstop1h 15mSouthwest
Thu 9/45:20 amOMA - STL
Nonstop1h 15mSouthwest
Deal found 7/31$177
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/95:40 pmSTL - OMA
1 stop16h 36mFrontier
Sun 8/107:51 pmOMA - STL
1 stop13h 20mFrontier
Deal found 7/29$195
This FlightHub deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:52 pmSTL - DSM
1 stop24h 07mFrontier
Fri 10/108:44 pmDSM - STL
1 stop12h 23mFrontier
Deal found 7/31$195
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/128:23 amSTL - OMA
1 stop8h 09mAmerican Airlines
Fri 9/192:57 pmOMA - STL
1 stop8h 10mAmerican Airlines
Deal found 7/29$196
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/276:40 amMCI - DSM
1 stop8h 00mSouthwest
Wed 8/274:35 pmDSM - MCI
1 stop5h 15mSouthwest
Deal found 7/30$202
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:32 pmSTL - OMA
1 stop5h 12mDelta
Wed 10/16:35 amOMA - STL
1 stop4h 55mDelta
Deal found 7/28$228
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/269:20 amSTL - DSM
1 stop5h 03mUnited Airlines
Wed 10/88:00 amDSM - STL
1 stop6h 27mUnited Airlines
Deal found 7/29$260
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:00 amSTL - DSM
1 stop6h 39mAmerican Airlines
Sun 8/247:32 amDSM - STL
1 stop16h 19mAmerican Airlines
Deal found 7/30$280
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:11 pmSTL - OMA
1 stop5h 15mUnited Airlines
Wed 10/13:06 pmOMA - STL
1 stop6h 54mUnited Airlines
Deal found 7/30$287
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/275:39 amMCI - OMA
1 stop9h 32mAmerican Airlines
Wed 9/312:04 pmOMA - MCI
1 stop8h 43mAmerican Airlines
Deal found 7/30$343

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Missouri to Iowa that are best for you.

Fly from

Missouri

Fly to

Iowa

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 8/27

9:15 pm-10:20 pm

Nonstop1h 05m

Des Moines

Wed 9/3

8:25 am-9:30 am

Nonstop1h 05m

$97

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 9/27

10:15 am-4:22 pm

1 stop6h 07m

Des Moines

Sat 10/4

12:32 pm-4:42 pm

1 stop4h 10m

$167

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Thu 8/28

4:25 pm-5:40 pm

Nonstop1h 15m

Omaha Eppley Airfield

Thu 9/4

5:20 am-6:35 am

Nonstop1h 15m

$177

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Sat 8/30

7:54 pm-7:50 pm

1 stop23h 56m

Omaha Eppley Airfield

Mon 9/1

8:45 pm-9:11 am

1 stop12h 26m

$195

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 10/8

7:52 pm-7:59 pm

1 stop24h 07m

Des Moines

Fri 10/10

8:44 pm-9:07 am

1 stop12h 23m

$195

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Fri 9/12

8:23 am-4:32 pm

1 stop8h 09m

Omaha Eppley Airfield

Fri 9/19

2:57 pm-11:07 pm

1 stop8h 10m

$196

Kansas CityDes Moines

MCI - DSM

MCIDSM

Kansas City

Wed 8/27

6:40 am-2:40 pm

1 stop8h 00m

Des Moines

Wed 8/27

4:35 pm-9:50 pm

1 stop5h 15m

$202

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Mon 9/29

5:32 pm-10:44 pm

1 stop5h 12m

Omaha Eppley Airfield

Wed 10/1

6:35 am-11:30 am

1 stop4h 55m

$228

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 9/26

9:20 am-2:23 pm

1 stop5h 03m

Des Moines

Wed 10/8

8:00 am-2:27 pm

1 stop6h 27m

$260

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 8/22

6:00 am-12:39 pm

1 stop6h 39m

Des Moines

Sun 8/24

7:32 am-11:51 pm

1 stop16h 19m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 38 results
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Best time to book a flight from Missouri to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Iowa

What is the cheapest month to book a flight from Missouri to Iowa?

Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IA?

Find hourly flight availability from Missouri to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Iowa as you normally would.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from Missouri to Iowa, such as Alaska Airlines, Southwest, and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Southwest
8.0
Very good
4,246 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,981 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,900 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to Iowa flight route?

    The Missouri to Iowa flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Missouri to Iowa one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from Missouri to Iowa for a low price.

  • Can I find deals for flights from Missouri to Iowa that include hotel bookings?

    Yes. In addition to deals on Missouri to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Iowa.

  • Can I find deals for business class flights from Missouri to Iowa?

    Yes. Cheapflights offers flight deals from Missouri to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Iowa?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Iowa

Discover the top 4 airlines that operate flights from Missouri to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Southern / MokuleleCheapest$51Average$83FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$127Average$310FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$218Average$318FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$218Average$318FlexibilityNo cancel feeOn-time71%

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