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$39+ Cheap flights from Missouri to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
jun. 21 — jun. 281
sáb. 6/21
sáb. 6/28
1 adult, Economy
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Cheap flight deals from Missouri to Iowa

Keep the following information in mind while searching for Missouri to Iowa flight deals. Data was last updated junio 16, 2025.

Round-trip from

$77
(Southwest)

One-way from

$39
(Southwest)

Good one-way deal

$143 or less
From Missouri to Iowa
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One-way flight from Missouri to Iowa
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Price to beat on a one-way flight from Missouri to Iowa.
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Find flight deals from Missouri to Iowa

Cheapest flights from Missouri to Iowa
Explore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 16, 2025.

This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/206:20 amSTL - DSM
1 stop8h 20mSouthwest
jue. 8/217:00 amDSM - STL
2 stops6h 05mSouthwest
Deal found 6/15$108
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/79:40 pmSTL - OMA
Nonstop1h 15mSouthwest
lun. 8/115:20 amOMA - STL
Nonstop1h 15mSouthwest
Deal found 6/14$137
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/74:32 pmSTL - OMA
1 stop7h 56mAmerican Airlines
lun. 8/112:17 pmOMA - STL
1 stop6h 01mAmerican Airlines
Deal found 6/14$145
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/410:55 amMCI - OMA
1 stop5h 25mSouthwest
lun. 8/116:25 pmOMA - MCI
1 stop4h 20mSouthwest
Deal found 6/14$157
This Booking.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/55:40 pmSTL - OMA
1 stop16h 36mFrontier
mar. 7/87:51 pmOMA - STL
1 stop13h 20mFrontier
Deal found 6/14$190
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/306:00 amSTL - DSM
1 stop3h 33mAmerican Airlines
mié. 8/65:29 pmDSM - STL
1 stop5h 36mAmerican Airlines
Deal found 6/15$198
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/45:45 amMCI - MLI
1 stop4h 57mAmerican Airlines
mar. 7/86:37 pmMLI - MCI
1 stop5h 22mAmerican Airlines
Deal found 6/15$224
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/292:15 pmSTL - DSM
2 stops6h 42mDelta
mar. 8/56:40 pmDSM - STL
1 stop5h 13mDelta
Deal found 6/14$239
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 7/276:50 pmMCI - DSM
1 stop5h 15mSouthwest
mar. 7/295:35 pmDSM - MCI
1 stop5h 15mSouthwest
Deal found 6/15$278
This Mytrip deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/75:26 pmSTL - DSM
1 stop15h 23mMultiple Airlines
lun. 8/111:59 pmDSM - STL
2 stops28h 42mMultiple Airlines
Deal found 6/16$309
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/210:00 amSTL - DSM
1 stop4h 41mUnited Airlines
dom. 7/66:50 pmDSM - STL
1 stop3h 55mUnited Airlines
Deal found 6/15$362
This Mytrip deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/3011:00 amMCI - DSM
1 stop7h 11mMultiple Airlines
vie. 7/41:15 pmDSM - MCI
2 stops31h 14mMultiple Airlines
Deal found 6/15$366

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 16, 2025.
Use the filters below to find and compare flights from Missouri to Iowa that are best for you.

Fly from

Missouri

Fly to

Iowa

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

mié. 8/20

9:15 pm-10:20 pm

Nonstop1h 05m

Des Moines

jue. 8/21

7:00 am-12:30 pm

1 stop5h 30m

$87

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

jue. 8/7

9:40 pm-10:55 pm

Nonstop1h 15m

Omaha Eppley Airfield

lun. 8/11

5:20 am-6:35 am

Nonstop1h 15m

$137

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

jue. 8/7

4:32 pm-12:28 am

1 stop7h 56m

Omaha Eppley Airfield

lun. 8/11

2:17 pm-8:18 pm

1 stop6h 01m

$145

Kansas CityOmaha

MCI - OMA

MCIOMA

Kansas City

lun. 8/4

10:55 am-4:20 pm

1 stop5h 25m

Omaha Eppley Airfield

lun. 8/11

6:25 pm-10:45 pm

1 stop4h 20m

$157

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

sáb. 7/5

5:40 pm-10:16 am

1 stop16h 36m

Omaha Eppley Airfield

mar. 7/8

7:51 pm-9:11 am

1 stop13h 20m

$190

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

mié. 7/30

6:00 am-9:33 am

1 stop3h 33m

Des Moines

mié. 8/6

5:29 pm-11:05 pm

1 stop5h 36m

$198

Kansas CityMoline

MCI - MLI

MCIMLI

Kansas City

vie. 7/4

5:45 am-10:42 am

1 stop4h 57m

Moline Quad-City

mar. 7/8

6:37 pm-11:59 pm

1 stop5h 22m

$224

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

mar. 7/29

2:15 pm-8:57 pm

2 stops6h 42m

Des Moines

mar. 8/5

6:40 pm-11:53 pm

1 stop5h 13m

$239

Kansas CityDes Moines

MCI - DSM

MCIDSM

Kansas City

dom. 7/27

6:50 pm-12:05 am

1 stop5h 15m

Des Moines

mar. 7/29

5:35 pm-10:50 pm

1 stop5h 15m

$278

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

jue. 8/7

5:26 pm-8:49 am

1 stop15h 23m

Des Moines

lun. 8/11

1:59 pm-6:41 pm

2 stops28h 42m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/16

Showing 1-10 of 43 results
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Best time to book a flight from Missouri to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Iowa

What is the cheapest month to book a flight from Missouri to Iowa?

Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IA?

Find hourly flight availability from Missouri to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Iowa as you normally would.

Weekly flight availability from Missouri to Iowa

Explore weekly flight availability from Missouri to Iowa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated junio 16, 2025.

The most flights from USMO to USIA are scheduled on a Monday (2 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in Iowa by month

Plan your trip to Iowa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Iowa ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Iowa when rainfall is around 1.0 in.

Temperature in Iowa by month

Plan your trip to Iowa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Iowa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated junio 16, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Missouri to Iowa to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,278 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,963 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,801 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Allegiant Air
7.3
Good
722 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Comfort

7.8

Overall

8.0

Food

7.1

Boarding

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to Iowa flight route?

    The Missouri to Iowa flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Missouri to Iowa one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $39. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Missouri to Iowa for a low price.

  • Can I find deals for flights from Missouri to Iowa that include hotel bookings?

    Yes. In addition to deals on Missouri to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Iowa.

  • Can I find deals for business class flights from Missouri to Iowa?

    Yes. Cheapflights offers flight deals from Missouri to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Iowa?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Iowa

Discover the top 3 airlines that operate flights from Missouri to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Southern / MokuleleCheapest$51Average$78FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$167Average$320FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$218Average$318FlexibilityNo cancel feeOn-time71%

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