$106+ Cheap flights from Missouri to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Apr 19 — Apr 261
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to IowaExplore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.
Explore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Fri 4/108:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/18![Frontier logo]()
$223
This Frontier deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:06 pm
STL
- DSM
1 stop17h 03m
Frontier
Fri 5/12:04 pm
DSM
- STL
1 stop5h 17m
Frontier
Deal found 3/18![Frontier logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Tue 5/128:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Deal found 3/19![Frontier logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:41 pm
STL
- OMA
2 stops24h 53m
Frontier
Sat 5/98:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/19![Frontier logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Tue 5/128:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Deal found 3/19![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Wed 5/138:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/19![Frontier logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Wed 5/138:19 pm
OMA
- STL
2 stops18h 29m
Frontier
Deal found 3/19![Frontier logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:41 pm
STL
- OMA
2 stops24h 53m
Frontier
Wed 5/138:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/19![Frontier logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Mon 4/208:58 pm
OMA
- STL
2 stops26h 21m
Frontier
Deal found 3/16![Frontier logo]()
$263
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:06 pm
MCI
- LSE
1 stop5h 48m
American Airlines
Wed 4/296:37 pm
LSE
- MCI
1 stop5h 22m
American Airlines
Deal found 3/15![American Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Mon 4/138:59 pm
OMA
- STL
2 stops33h 51m
Frontier
Deal found 3/18![Frontier logo]()
$279
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:35 am
STL
- DSM
1 stop5h 30m
Southwest
Wed 4/226:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 3/18![Southwest logo]()
$279
Best flights from Missouri to IowaDiscover carefully curated flight deals from Missouri to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 20, 2026.
Discover carefully curated flight deals from Missouri to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 20, 2026.
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:06 pm
MCI
- LSE
1 stop5h 48m
American Airlines
Wed 4/296:37 pm
LSE
- MCI
1 stop5h 22m
American Airlines
Deal found 3/15![American Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:35 am
STL
- DSM
1 stop5h 30m
Southwest
Wed 4/226:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 3/18![Southwest logo]()
$279
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:10 am
STL
- FOD
1 stop4h 55m
United Airlines
Sat 4/42:36 pm
FOD
- STL
1 stop4h 55m
United Airlines
Deal found 3/16![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:35 pm
STL
- OMA
1 stop5h 14m
Delta
Wed 4/226:55 am
OMA
- STL
1 stop4h 37m
Delta
Deal found 3/17![Delta logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1212:24 pm
MCI
- OMA
2 stops28h 47m
Multiple Airlines
Sun 4/198:58 pm
OMA
- MCI
1 stop16h 32m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$448
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Mon 5/45:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/16![Southwest logo]()
$307
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:00 am
MCI
- LSE
1 stop6h 01m
American Airlines
Mon 4/66:29 pm
LSE
- MCI
1 stop5h 25m
American Airlines
Deal found 3/18![American Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:36 pm
MCI
- MLI
1 stop4h 23m
United Airlines
Thu 7/306:30 am
MLI
- MCI
1 stop3h 59m
United Airlines
Deal found 3/17![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
STL
- DSM
1 stop4h 48m
Delta
Fri 4/310:28 am
DSM
- STL
1 stop6h 04m
Delta
Deal found 3/19![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:00 pm
STL
- OMA
Nonstop1h 15m
Southwest
Mon 4/135:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/15![Southwest logo]()
$313
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:00 am
STL
- DSM
1 stop4h 27m
United Airlines
Wed 6/1711:23 am
DSM
- STL
1 stop4h 23m
United Airlines
Deal found 3/16![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Sat 5/92:50 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/15![Southwest logo]()
$313
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:10 am
STL
- DSM
1 stop5h 15m
United Airlines
Sat 4/48:04 am
DSM
- STL
1 stop4h 18m
United Airlines
Deal found 3/16![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Tue 4/218:05 am
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/15![Southwest logo]()
$313
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:20 pm
STL
- DSM
1 stop5h 00m
Southwest
Fri 4/101:45 pm
DSM
- STL
1 stop7h 20m
Southwest
Deal found 3/15![Southwest logo]()
$316
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:45 am
STL
- FOD
1 stop6h 16m
United Airlines
Sat 5/22:36 pm
FOD
- STL
1 stop6h 37m
United Airlines
Deal found 3/16![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 pm
SGF
- LSE
1 stop5h 36m
American Airlines
Mon 4/66:29 pm
LSE
- SGF
1 stop4h 06m
American Airlines
Deal found 3/18![American Airlines logo]()
$464
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:40 am
STL
- DSM
1 stop6h 05m
Southwest
Fri 5/14:20 pm
DSM
- STL
2 stops7h 55m
Southwest
Deal found 3/16![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:42 am
JLN
- MLI
1 stop4h 16m
United Airlines
Sat 8/296:30 am
MLI
- JLN
1 stop6h 48m
United Airlines
Deal found 3/15![United Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:45 am
MCI
- MLI
1 stop28h 31m
Multiple Airlines
Wed 4/12:41 pm
MLI
- MCI
2 stops29h 20m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$555
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:00 pm
STL
- DSM
1 stop6h 55m
Southwest
Sun 5/315:20 am
DSM
- STL
1 stop4h 10m
Southwest
Deal found 3/17![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:00 am
MCI
- MLI
1 stop6h 09m
United Airlines
Wed 4/226:30 am
MLI
- MCI
1 stop3h 57m
United Airlines
Deal found 3/18![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:05 am
SGF
- LSE
2 stops10h 54m
American Airlines
Sun 4/55:09 am
LSE
- SGF
2 stops12h 41m
American Airlines
Deal found 3/16![American Airlines logo]()
$519
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:10 am
STL
- DSM
1 stop6h 20m
Southwest
Wed 4/86:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 3/19![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:00 pm
MCI
- MLI
1 stop4h 06m
United Airlines
Sat 4/46:30 am
MLI
- MCI
1 stop5h 54m
United Airlines
Deal found 3/16![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:15 am
STL
- OMA
2 stops7h 00m
Southwest
Wed 4/221:55 pm
OMA
- STL
1 stop7h 20m
Southwest
Deal found 3/17![Southwest logo]()
$326
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:05 pm
SGF
- LSE
1 stop5h 49m
American Airlines
Thu 4/166:37 pm
LSE
- SGF
1 stop4h 01m
American Airlines
Deal found 3/19![American Airlines logo]()
$526
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:00 am
MCI
- MLI
1 stop6h 09m
United Airlines
Sun 4/58:30 am
MLI
- MCI
1 stop5h 55m
United Airlines
Deal found 3/17![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:30 pm
STL
- DSM
1 stop7h 50m
Southwest
Mon 4/64:20 pm
DSM
- STL
2 stops7h 45m
Southwest
Deal found 3/18![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
SGF
- MLI
1 stop6h 58m
United Airlines
Wed 8/266:30 am
MLI
- SGF
1 stop4h 13m
United Airlines
Deal found 3/15![United Airlines logo]()
$369
Last-minute flights from Missouri to IowaDiscover last-minute flight deals from Missouri to Iowa. Data last updated March 20, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Iowa. Data last updated March 20, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/319:10 am
STL
- FOD
1 stop4h 55m
United Airlines
Sat 4/42:36 pm
FOD
- STL
1 stop4h 55m
United Airlines
Deal found 3/16![United Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:00 am
MCI
- LSE
1 stop6h 01m
American Airlines
Mon 4/66:29 pm
LSE
- MCI
1 stop5h 25m
American Airlines
Deal found 3/18![American Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Fri 4/108:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/18![Frontier logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Mon 4/138:59 pm
OMA
- STL
2 stops33h 51m
Frontier
Deal found 3/18![Frontier logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Sun 4/128:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/18![Frontier logo]()
$306
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Tue 4/214:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/17![Southwest logo]()
$301
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:30 am
STL
- OMA
1 stop4h 02m
United Airlines
Tue 4/213:22 pm
OMA
- STL
1 stop6h 30m
United Airlines
Deal found 3/17![United Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:06 pm
MCI
- LSE
1 stop5h 48m
American Airlines
Wed 4/296:37 pm
LSE
- MCI
1 stop5h 22m
American Airlines
Deal found 3/15![American Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:35 am
STL
- DSM
1 stop5h 30m
Southwest
Wed 4/226:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 3/18![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Mon 4/208:58 pm
OMA
- STL
2 stops26h 21m
Frontier
Deal found 3/16![Frontier logo]()
$263
This Frontier deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:06 pm
STL
- DSM
1 stop17h 03m
Frontier
Fri 5/12:04 pm
DSM
- STL
1 stop5h 17m
Frontier
Deal found 3/18![Frontier logo]()
$224
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Mon 5/45:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 3/16![Southwest logo]()
$307
One-way flights from Missouri to IowaSearch for one-way flight options from Missouri to Iowa. Find affordable one-way fares based on user searches. Data last updated March 20, 2026.
Search for one-way flight options from Missouri to Iowa. Find affordable one-way fares based on user searches. Data last updated March 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 3/18![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 3/18![Frontier logo]()
$115
This Trip.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/19![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/17![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- DSM
2 stops19h 37m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:33 pm
STL
- OMA
2 stops25h 01m
Frontier
Deal found 3/18![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:15 pm
MCI
- OMA
1 stop5h 49m
Frontier
Deal found 3/16![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Deal found 3/18![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:50 am
STL
- DSM
2 stops13h 07m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$138
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
STL
- DSM
1 stop5h 05m
Delta
Deal found 3/16![Delta logo]()
$140
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:15 am
STL
- DSM
2 stops13h 21m
Delta
Deal found 3/18![Delta logo]()
$145
This Booking.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/318:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 3/15![Frontier logo]()
$147
Find flight deals from Missouri to Iowa
Keep the following information in mind while searching for Missouri to Iowa flight deals. Data was last updated March 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $223 (Kiwi.com) |
One-way from | $106 (Kiwi.com) |
Popular in | January |
Cheapest in | October |
Average price | $238 |
Good one-way deal | $194 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Missouri to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityLa Crosse
MCI - LSE
MCILSE
Kansas City
Wed 4/15
6:06 pm-11:54 pm
1 stop5h 48m
La Crosse
Wed 4/29
6:37 pm-11:59 pm
1 stop5h 22m
$278
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Wed 4/15
8:35 am-2:05 pm
1 stop5h 30m
Des Moines
Wed 4/22
6:30 pm-11:10 pm
1 stop4h 40m
$279
St. LouisFort Dodge
STL - FOD
STLFOD
Lambert-St Louis
Tue 3/31
9:10 am-2:05 pm
1 stop4h 55m
Fort Dodge
Sat 4/4
2:36 pm-7:31 pm
1 stop4h 55m
$299
St. LouisOmaha
STL - OMA
STLOMA
Lambert-St Louis
Wed 4/29
8:25 am-9:45 am
Nonstop1h 20m
Omaha Eppley Airfield
Mon 5/4
5:40 pm-6:55 pm
Nonstop1h 15m
$307
Kansas CityLa Crosse
MCI - LSE
MCILSE
Kansas City
Thu 4/2
5:00 am-11:01 am
1 stop6h 01m
La Crosse
Mon 4/6
6:29 pm-11:54 pm
1 stop5h 25m
$308
St. LouisOmaha
STL - OMA
STLOMA
Lambert-St Louis
Wed 4/15
5:35 pm-10:49 pm
1 stop5h 14m
Omaha Eppley Airfield
Wed 4/22
6:55 am-11:32 am
1 stop4h 37m
$311
Quickest round-trip
St. LouisOmaha
STL - OMA
STLOMA
Lambert-St Louis
Sat 4/11
7:00 pm-8:15 pm
Nonstop1h 15m
Omaha Eppley Airfield
Mon 4/13
5:40 pm-6:55 pm
Nonstop1h 15m
$313
St. LouisOmaha
STL - OMA
STLOMA
Lambert-St Louis
Wed 5/6
8:25 am-9:45 am
Nonstop1h 20m
Omaha Eppley Airfield
Sat 5/9
2:50 pm-4:05 pm
Nonstop1h 15m
$313
St. LouisOmaha
STL - OMA
STLOMA
Lambert-St Louis
Tue 4/14
8:50 pm-10:10 pm
Nonstop1h 20m
Omaha Eppley Airfield
Tue 4/21
8:05 am-9:20 am
Nonstop1h 15m
$313
Kansas CityMoline
MCI - MLI
MCIMLI
Kansas City
Sat 7/25
6:36 pm-10:59 pm
1 stop4h 23m
Moline Quad-City
Thu 7/30
6:30 am-10:29 am
1 stop3h 59m
$314
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Missouri with our price prediction graph.
MCI-LSE
STL-DSM
STL-FOD
STL-OMA
MCI-OMA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Iowa
USMO-USIA
MCI-LSE
STL-DSM
STL-FOD
STL-OMA
What is the cheapest time of day to fly from MO to IA?
Find hourly flight availability from Missouri to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 20, 2026.
When flying from Missouri to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 36% versus a flight in the morning.
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated March 20, 2026.
Read through reviews of airlines operating flights from Missouri to Iowa, such as Southwest and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Missouri to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Iowa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Iowa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Iowa by cabin class
Find flights from Missouri to Iowa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Iowa flights
Browse other Missouri and Iowa flight options. Last updated on March 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Iowa
Find the right flight back to Missouri after your stay in Iowa
Missouri to Iowa flights
Consider these flights traveling from Missouri to Iowa.
Top 2 airlines flying from Missouri to Iowa
Discover the top 2 airlines that operate flights from Missouri to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$309 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$142 | Average$306 | FlexibilityNo cancel fee | On-time71% |