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$275+ Cheap flights from Panama to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
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Find flight deals from Panama to Indianapolis

Cheapest flights from Panama to Indianapolis
Explore the most affordable flight options available from Panama to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:00 amPTY - IND
1 stop10h 56mUnited Airlines
Tue 1/69:00 amIND - PTY
1 stop8h 07mUnited Airlines
Deal found 10/12$505
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:50 pmPTY - IND
2 stops17h 55mAmerican Airlines
Wed 1/144:45 pmIND - PTY
2 stops20h 42mAmerican Airlines
Deal found 10/12$518
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:55 pmPTY - IND
2 stops20h 23mAmerican Airlines
Fri 1/96:00 amIND - PTY
2 stops9h 38mAmerican Airlines
Deal found 10/12$524
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2211:35 amPTY - IND
2 stops12h 09mUnited Airlines
Fri 1/92:00 pmIND - PTY
2 stops15h 10mUnited Airlines
Deal found 10/12$526
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:55 pmPTY - IND
2 stops13h 22mUnited Airlines
Wed 12/245:05 pmIND - PTY
1 stop21h 40mUnited Airlines
Deal found 10/11$532
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:53 pmPTY - IND
1 stop9h 06mAmerican Airlines
Sun 1/46:00 amIND - PTY
1 stop7h 53mAmerican Airlines
Deal found 10/11$535
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/103:37 pmPTY - IND
1 stop8h 49mDelta
Tue 11/186:00 amIND - PTY
1 stop8h 12mDelta
Deal found 10/10$548
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:41 pmPTY - IND
2 stops18h 32mUnited Airlines
Fri 1/99:00 amIND - PTY
1 stop10h 38mUnited Airlines
Deal found 10/11$567
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:49 pmPTY - IND
1 stop9h 07mAmerican Airlines
Tue 11/186:00 amIND - PTY
1 stop7h 49mAmerican Airlines
Deal found 10/11$588
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/282:21 pmPTY - IND
1 stop9h 01mDelta
Fri 11/146:00 amIND - PTY
1 stop13h 59mDelta
Deal found 10/12$591

Cheap flight deals from Panama to Indianapolis

Keep the following information in mind while searching for Panama to Indianapolis flight deals. Data was last updated October 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$505
(United Airlines)

One-way from

$275
(Kiwi.com)

Popular in

August

Cheapest in

December

Average price

$637
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
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From Panama to Indianapolis
Search Deals
One-way flight from Panama to Indianapolis
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($76 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from Panama to Indianapolis that are best for you.

Fly from

Panama

Fly to

Indianapolis

Route

Depart

Return

Price

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 12/25

10:00 am-8:56 pm

1 stop10h 56m

Indianapolis

Tue 1/6

9:00 am-5:07 pm

1 stop8h 07m

$505

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 12/10

2:50 pm-9:24 am

2 stops18h 34m

Indianapolis

Wed 1/14

4:45 pm-1:27 pm

2 stops20h 42m

$518

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 12/30

4:55 pm-1:18 pm

2 stops20h 23m

Indianapolis

Fri 1/9

6:00 am-3:38 pm

2 stops9h 38m

$524

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Fri 10/31

8:40 am-9:48 am

2 stops24h 08m

$275

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 11/12

3:37 pm-12:26 am

1 stop8h 49m

$307

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 11/12

8:55 am-11:18 pm

2 stops14h 23m

$316

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Fri 10/31

3:41 pm-8:16 pm

1 stop27h 35m

$350

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Mon 1/5

6:41 pm-10:28 am

1 stop15h 47m

$409

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Mon 1/5

4:55 pm-12:22 pm

2 stops19h 27m

$471

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 1/6

12:03 pm-10:31 am

2 stops46h 28m

$500

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/12

Best time to book a flight from Panama to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Indianapolis

What is the cheapest month to book a flight from Panama to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $254). Flying from Panama to Indianapolis in January is currently the most expensive (average of $556). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IND?

Find hourly flight availability from Panama to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama to Indianapolis at noon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated October 13, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Panama to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,974 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,045 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Panama to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Panama?

    For a flight from Panama to Indianapolis, you will be flying into Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Panama to Indianapolis?

    A quick flight from Panama to Indianapolis can take about 10h 56m. United Airlines provides one of the quickest options available for as low as $505. Panama and Indianapolis are separated by a distance of 2158 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Panama to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Indianapolis.

  • Can I find deals for business class flights from Panama to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $254). Flying from Panama to Indianapolis in January is currently the most expensive (average of $556). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Tegucigalpa to Dayton flights

Top 3 airlines flying from Panama to Indianapolis

Discover the top 3 airlines that operate flights from Panama to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$312Average$584FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$481Average$640FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$496Average$586FlexibilityNo cancel feeOn-time71%

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