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$298+ Cheap flights from Panama to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Panama to Indianapolis

Cheapest flights from Panama to Indianapolis
Explore the most affordable flight options available from Panama to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:55 pmPTY - IND
2 stops21h 31mAmerican Airlines
Fri 1/96:00 amIND - PTY
2 stops9h 38mAmerican Airlines
Deal found 12/2$561
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:41 pmPTY - IND
1 stop18h 09mUnited Airlines
Fri 1/99:00 amIND - PTY
1 stop10h 38mUnited Airlines
Deal found 12/2$578
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/152:50 pmPTY - IND
1 stop9h 09mAmerican Airlines
Sun 6/147:28 pmIND - PTY
2 stops18h 02mAmerican Airlines
Deal found 12/3$632
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:55 pmPTY - IND
1 stop9h 20mUnited Airlines
Sun 12/145:14 pmIND - PTY
1 stop23h 53mUnited Airlines
Deal found 12/2$636
This United Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1011:35 amPTY - IND
1 stop11h 34mUnited Airlines
Wed 1/149:00 amIND - PTY
1 stop8h 07mUnited Airlines
Deal found 12/1$698
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:50 pmPTY - IND
2 stops17h 55mAmerican Airlines
Sun 12/147:22 pmIND - PTY
2 stops18h 25mAmerican Airlines
Deal found 12/2$724
This Delta deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/103:46 pmPTY - IND
1 stop8h 40mDelta
Wed 1/147:00 amIND - PTY
1 stop6h 55mDelta
Deal found 12/3$730
This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:43 pmPTY - IND
2 stops16h 45mAmerican Airlines
Wed 1/145:07 pmIND - PTY
2 stops20h 20mAmerican Airlines
Deal found 12/1$750
This Copa Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/159:11 amPTY - IND
1 stop9h 50mCopa Airlines
Sun 6/146:00 amIND - PTY
1 stop15h 41mCopa Airlines
Deal found 12/3$752

Find flight deals from Panama to Indianapolis

Keep the following information in mind while searching for Panama to Indianapolis flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$505
(United Airlines)

One-way from

$298
(Kiwi.com)

Popular in

August

Cheapest in

December

Average price

$516
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
Search Deals
From Panama to Indianapolis
Search Deals
One-way flight from Panama to Indianapolis
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($88 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Panama to Indianapolis that are best for you.

Fly from

Panama

Fly to

Indianapolis

Route

Depart

Return

Price

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 1/28

8:55 am-10:48 am

1 stop25h 53m

Indianapolis

Sun 2/8

9:00 am-2:45 pm

1 stop29h 45m

$505

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 3/3

8:55 am-8:51 pm

1 stop11h 56m

Indianapolis

Wed 3/18

6:45 am-1:45 pm

1 stop8h 00m

$505

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 2/5

3:20 pm-8:59 am

1 stop17h 39m

Indianapolis

Mon 2/9

7:00 am-1:55 pm

1 stop6h 55m

$514

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 2/5

4:41 pm-11:32 am

2 stops18h 51m

Indianapolis

Mon 2/9

6:00 pm-2:45 pm

2 stops20h 45m

$518

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 12/11

7:50 pm-7:43 am

3 stops35h 53m

$298

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 12/11

3:46 pm-12:26 am

1 stop8h 40m

$351

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Best time to book a flight from Panama to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Indianapolis

What is the cheapest month to book a flight from Panama to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $254). Flying from Panama to Indianapolis in January is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IND?

Find hourly flight availability from Panama to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama to Indianapolis at noon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated December 4, 2025.
See what other customers who have flown with Delta and United Airlines from Panama to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,066 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Panama?

    For a flight from Panama to Indianapolis, you will be flying into Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Panama to Indianapolis?

    A quick flight from Panama to Indianapolis can take about 25h 53m. United Airlines provides one of the quickest options available for as low as $505. Panama and Indianapolis are separated by a distance of 2158 mi.

  • Can I find deals for flights from Panama to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Indianapolis.

  • Can I find deals for business class flights from Panama to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $254). Flying from Panama to Indianapolis in January is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Greenwood
Anderson
Kokomo
Plainfield
Franklin
Carmel
Crawfordsville
Bloomington
Speedway

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Indianapolis

Discover the top 2 airlines that operate flights from Panama to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$344Average$590FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$481Average$644FlexibilityNo cancel feeOn-time69%

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