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$527+ Cheap flights from Panama to Indianapolis (IND)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IND
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from Panama to Indianapolis

Cheapest flights from Panama to Indianapolis
Explore the most affordable flight options available from Panama to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:00 am
PTY
-
IND
1 stop12h 25m
United Airlines
Thu 6/46:00 am
IND
-
PTY
2 stops11h 12m
United Airlines
Deal found 2/3$527
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/12:55 am
PTY
-
IND
3 stops43h 53m
Multiple Airlines
Mon 3/96:00 am
IND
-
PTY
3 stops33h 00m
Multiple Airlines
Deal found 2/2$536
This deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:00 am
PTY
-
IND
1 stop10h 32m
United Airlines
Sun 5/179:10 am
IND
-
PTY
1 stop10h 27m
United Airlines
Deal found 2/2$549
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:10 pm
PTY
-
IND
2 stops20h 03m
American Airlines
Thu 6/45:28 pm
IND
-
PTY
2 stops19h 42m
American Airlines
Deal found 2/2$551
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/34:41 pm
PTY
-
IND
2 stops22h 17m
United Airlines
Wed 3/187:15 am
IND
-
PTY
2 stops12h 23m
United Airlines
Deal found 2/3$570
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/283:41 pm
PTY
-
IND
1 stop18h 05m
United Airlines
Sat 4/411:43 am
IND
-
PTY
1 stop7h 54m
United Airlines
Deal found 2/3$579
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:00 am
PTY
-
IND
1 stop11h 00m
United Airlines
Tue 3/109:00 am
IND
-
PTY
1 stop10h 38m
United Airlines
Deal found 2/3$601

Find flight deals from Panama to Indianapolis

Keep the following information in mind while searching for Panama to Indianapolis flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$527
(United Airlines)

Popular in

August

Cheapest in

March

Average price

$644
Provider with most accurate pricing for Panama City Tocumen Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Indianapolis flights.
Search Deals
From Panama to Indianapolis
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Panama to Indianapolis that are best for you.

Fly from

Panama

Fly to

Indianapolis

Route

Depart

Return

Price

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 5/28

10:00 am-7:58 pm

1 stop8h 58m

Indianapolis

Thu 6/4

7:00 am-6:37 pm

1 stop12h 37m

$527

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Wed 4/15

10:00 am-9:32 pm

1 stop10h 32m

Indianapolis

Mon 5/18

9:10 am-6:37 pm

1 stop10h 27m

$527

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Tue 4/7

3:30 pm-10:46 am

1 stop18h 16m

Indianapolis

Wed 4/22

9:24 am-4:12 pm

1 stop7h 48m

$527

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Sun 3/1

2:55 am-10:48 pm

3 stops43h 53m

Indianapolis

Mon 3/9

6:00 am-2:00 pm

3 stops33h 00m

$536

Panama CityIndianapolis

PTY - IND

PTYIND

Panama City Tocumen Intl

Thu 4/16

10:00 am-9:32 pm

1 stop10h 32m

Indianapolis

Sun 5/17

9:10 am-6:37 pm

1 stop10h 27m

$549

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Best time to book a flight from Panama to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Indianapolis

What is the cheapest month to book a flight from Panama to Indianapolis?

Currently, June is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $254). Flying from Panama to Indianapolis in September is currently the most expensive (average of $524). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated February 4, 2026.
See what other customers who have flown with Delta and United Airlines from Panama to Indianapolis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,138 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,138 reviews
Delta
7.9
Good
8,138 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,236 reviews
Delta
7.9
Good
8,138 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Panama?

    For a flight from Panama to Indianapolis, you will be flying into Indianapolis. Indianapolis (IND) is just 8.3 mi from the center of the city.

  • How long is the flight from Panama to Indianapolis?

    A quick flight from Panama to Indianapolis can take about 8h 58m. United Airlines provides one of the quickest options available for as low as $527. Panama and Indianapolis are separated by a distance of 2158 mi.

  • Can I find deals for flights from Panama to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Panama to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Indianapolis.

  • Can I find deals for business class flights from Panama to Indianapolis?

    Yes. Cheapflights offers flight deals from Panama to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Indianapolis?

    Currently, June is the cheapest month in which you can book a flight from Panama to Indianapolis (average of $254). Flying from Panama to Indianapolis in September is currently the most expensive (average of $524). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Fishers
Noblesville
Greenwood
Plainfield
Anderson
Kokomo
Mooresville
Franklin
Carmel
Crawfordsville
Bloomington

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Panama to Indianapolis

Discover the top 2 airlines that operate flights from Panama to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$311Average$568FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$458Average$665FlexibilityNo cancel feeOn-time69%

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