$128+ Cheap flights from Knoxville to Greenville (TYS - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — GSP
Oct 24 — Oct 311
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Greenville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to GreenvilleExplore the most affordable flight options available from Knoxville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Knoxville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:40 am -
1 stop4h 21m
Tue 11/1012:12 pm -
1 stop3h 03m
Deal found 9/21![Delta logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:04 pm -
2 stops25h 40m
Tue 11/1011:28 am -
1 stop26h 17m
Deal found 9/21![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:00 am -
1 stop8h 47m
Mon 10/262:49 pm -
1 stop26h 25m
Deal found 9/21![Multiple Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:23 pm -
1 stop4h 28m
Sun 10/255:40 am -
1 stop5h 14m
Deal found 9/22![Delta logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
2 stops22h 16m
Sun 10/253:18 pm -
1 stop4h 22m
Deal found 9/21![Multiple Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:58 pm -
1 stop3h 23m
Mon 10/268:33 pm -
1 stop3h 22m
Deal found 9/21![American Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:40 am -
1 stop3h 43m
Sun 10/117:14 pm -
1 stop2h 54m
Deal found 9/22![Delta logo]()
$467
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:04 pm -
2 stops25h 40m
Sat 10/102:30 pm -
1 stop5h 22m
Deal found 9/21![Multiple Airlines logo]()
$490
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:15 pm -
1 stop3h 50m
Sat 10/1012:45 pm -
1 stop6h 55m
Deal found 9/21![Southwest logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:54 am -
1 stop7h 36m
Sat 9/268:24 pm -
2 stops13h 40m
Deal found 9/22![Multiple Airlines logo]()
$620
Best flights from Knoxville to GreenvilleDiscover carefully curated flight deals from Knoxville to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Knoxville to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/132:19 pm -
1 stop4h 36m
Wed 1/205:12 pm -
1 stop3h 34m
Deal found 9/20![American Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:23 pm -
1 stop4h 28m
Sun 10/255:40 am -
1 stop5h 14m
Deal found 9/22![Delta logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
2 stops22h 16m
Sun 10/253:18 pm -
1 stop4h 22m
Deal found 9/21![Multiple Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:15 am -
2 stops12h 35m
Wed 1/202:54 pm -
1 stop9h 11m
Deal found 9/20![United Airlines logo]()
$558
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:15 pm -
1 stop3h 50m
Sat 10/1012:45 pm -
1 stop6h 55m
Deal found 9/21![Southwest logo]()
$617
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:58 pm -
1 stop3h 23m
Mon 10/268:33 pm -
1 stop3h 22m
Deal found 9/21![American Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:40 am -
1 stop3h 43m
Sun 10/117:14 pm -
1 stop2h 54m
Deal found 9/22![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:25 pm -
1 stop3h 25m
Mon 10/262:10 pm -
2 stops8h 35m
Deal found 9/21![Southwest logo]()
$622
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:14 pm -
2 stops17h 18m
Sun 10/119:44 am -
1 stop9h 24m
Deal found 9/22![Multiple Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:25 pm -
2 stops21h 38m
Sun 10/256:20 am -
1 stop14h 34m
Deal found 9/22![United Airlines logo]()
$821
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:35 pm -
2 stops17h 55m
Fri 10/307:43 pm -
2 stops14h 24m
Deal found 9/23![United Airlines logo]()
$827
Last-minute flights from Knoxville to GreenvilleDiscover last-minute flight deals from Knoxville to Greenville. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Greenville. Data last updated September 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:54 am -
1 stop7h 36m
Sat 9/268:24 pm -
2 stops13h 40m
Deal found 9/22![Multiple Airlines logo]()
$620
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:04 pm -
2 stops25h 40m
Sat 10/102:30 pm -
1 stop5h 22m
Deal found 9/21![Multiple Airlines logo]()
$490
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:15 pm -
1 stop3h 50m
Sat 10/1012:45 pm -
1 stop6h 55m
Deal found 9/21![Southwest logo]()
$617
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:40 am -
1 stop3h 43m
Sun 10/117:14 pm -
1 stop2h 54m
Deal found 9/22![Delta logo]()
$467
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:14 pm -
2 stops17h 18m
Sun 10/119:44 am -
1 stop9h 24m
Deal found 9/22![Multiple Airlines logo]()
$626
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:00 am -
1 stop8h 47m
Mon 10/262:49 pm -
1 stop26h 25m
Deal found 9/21![Multiple Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:58 pm -
1 stop3h 23m
Mon 10/268:33 pm -
1 stop3h 22m
Deal found 9/21![American Airlines logo]()
$423
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:25 pm -
1 stop3h 25m
Mon 10/262:10 pm -
2 stops8h 35m
Deal found 9/21![Southwest logo]()
$622
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:23 pm -
1 stop4h 28m
Sun 10/255:40 am -
1 stop5h 14m
Deal found 9/22![Delta logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
2 stops22h 16m
Sun 10/253:18 pm -
1 stop4h 22m
Deal found 9/21![Multiple Airlines logo]()
$417
One-way flights from Knoxville to GreenvilleSearch for one-way flight options from Knoxville to Greenville. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Knoxville to Greenville. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:37 pm -
1 stop14h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:35 am -
1 stop6h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Allegiant Air logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:20 am -
2 stops12h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Multiple Airlines logo]()
$174
Find flight deals from Knoxville to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $287 (American Airlines) |
One-way from | $128 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Knoxville to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Thu 11/5
5:37 pm-8:15 am
1 stop14h 38m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$128
Quickest round-trip
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Fri 11/6
8:35 am-2:42 pm
1 stop6h 07m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$150
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Fri 11/6
7:20 am-8:12 pm
2 stops12h 52m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Wed 1/13
2:19 pm-6:55 pm
1 stop4h 36m
Greenville
Wed 1/20
5:12 pm-8:46 pm
1 stop3h 34m
$287
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Fri 10/23
6:23 pm-10:51 pm
1 stop4h 28m
Greenville
Sun 10/25
5:40 am-10:54 am
1 stop5h 14m
$413
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Fri 10/23
9:28 pm-7:44 pm
2 stops22h 16m
Greenville
Sun 10/25
3:18 pm-7:40 pm
1 stop4h 22m
$417
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Mon 10/19
7:58 pm-11:21 pm
1 stop3h 23m
Greenville
Mon 10/26
8:33 pm-11:55 pm
1 stop3h 22m
$423
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Wed 10/7
5:40 am-9:23 am
1 stop3h 43m
Greenville
Sun 10/11
7:14 pm-10:08 pm
1 stop2h 54m
$467
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Wed 1/13
6:15 am-6:50 pm
2 stops12h 35m
Greenville
Wed 1/20
2:54 pm-12:05 am
1 stop9h 11m
$558
KnoxvilleGreenville
TYS Knoxville McGhee Tyson - GSP Greenville
TYSGSP
Knoxville McGhee Tyson
Tue 10/6
5:15 pm-9:05 pm
1 stop3h 50m
Greenville
Sat 10/10
12:45 pm-7:40 pm
1 stop6h 55m
$617
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Greenville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Knoxville with our price prediction graph.
TYS-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Greenville flight routes
Other flight options
Other flights from Knoxville
Popular flights