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$110+ Cheap flights from Iowa to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSP
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Iowa to Greenville

Keep the following information in mind while searching for Iowa to Greenville flight deals. Data was last updated September 11, 2025.

Round-trip from

$219
(American Airlines)

One-way from

$110
(American Airlines)

Popular in

November

Cheapest in

June

Average price

$316
From Iowa to Greenville
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One-way flight from Iowa to Greenville
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Highest demand for flights based on searches. 16% potential increase in price ($79 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($27 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Iowa to Greenville

Cheapest flights from Iowa to Greenville
Explore the most affordable flight options available from Iowa to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:00 amOMA - GSP
1 stop5h 37mAmerican Airlines
Tue 11/188:35 amGSP - OMA
1 stop6h 35mAmerican Airlines
Deal found 9/9$219
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:00 amCID - GSP
1 stop5h 47mDelta
Wed 10/155:36 pmGSP - CID
1 stop5h 58mDelta
Deal found 9/10$249
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:50 amMLI - GSP
1 stop5h 03mUnited Airlines
Mon 10/133:55 pmGSP - MLI
1 stop6h 10mUnited Airlines
Deal found 9/10$249
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/258:00 amCID - GSP
1 stop4h 36mUnited Airlines
Sun 10/265:28 pmGSP - CID
1 stop5h 01mUnited Airlines
Deal found 9/8$250
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/74:23 pmCID - GSP
2 stops6h 32mDelta
Tue 10/145:30 amGSP - CID
2 stops7h 15mDelta
Deal found 9/10$259
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:09 amCID - GSP
1 stop5h 48mAmerican Airlines
Mon 9/295:20 pmGSP - CID
2 stops7h 39mAmerican Airlines
Deal found 9/10$264
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:39 pmCID - GSP
1 stop4h 12mAmerican Airlines
Tue 10/148:04 pmGSP - CID
1 stop4h 45mAmerican Airlines
Deal found 9/10$279
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:00 amCID - GSP
1 stop5h 47mDelta
Thu 10/165:30 amGSP - CID
2 stops7h 15mDelta
Deal found 9/10$284
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/302:08 pmOMA - GSP
1 stop6h 26mDelta
Sun 10/55:30 amGSP - OMA
1 stop5h 06mDelta
Deal found 9/11$295
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/93:17 pmOMA - GSP
1 stop5h 01mUnited Airlines
Thu 10/1612:21 pmGSP - OMA
1 stop6h 13mUnited Airlines
Deal found 9/10$299
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amCID - GSP
1 stop5h 47mDelta
Wed 10/155:36 pmGSP - CID
1 stop5h 58mDelta
Deal found 9/10$303
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/201:06 pmDSM - GSP
1 stop5h 38mAmerican Airlines
Sun 11/236:00 amGSP - DSM
1 stop5h 40mAmerican Airlines
Deal found 9/10$308

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Iowa to Greenville that are best for you.

Fly from

Iowa

Fly to

Greenville

Route

Depart

Return

Price

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Wed 11/12

5:00 am-11:37 am

1 stop5h 37m

Greenville

Tue 11/18

8:35 am-2:10 pm

1 stop6h 35m

$219

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Fri 10/10

11:25 am-4:53 pm

1 stop4h 28m

Greenville

Tue 10/14

3:55 pm-7:07 pm

1 stop4h 12m

$249

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Tue 10/7

6:00 am-12:47 pm

1 stop5h 47m

Greenville

Sat 10/11

5:16 pm-10:34 pm

1 stop6h 18m

$249

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Thu 10/9

3:40 pm-9:18 pm

1 stop4h 38m

Greenville

Sun 10/12

5:34 pm-9:05 pm

1 stop4h 31m

$249

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Wed 2/18

5:00 pm-11:36 pm

1 stop5h 36m

Greenville

Sat 2/21

5:05 pm-10:34 pm

1 stop6h 29m

$249

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Thu 10/9

10:50 am-4:53 pm

1 stop5h 03m

Greenville

Mon 10/13

3:55 pm-9:05 pm

1 stop6h 10m

$249

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Sat 10/25

8:00 am-1:36 pm

1 stop4h 36m

Greenville

Sun 10/26

5:28 pm-9:29 pm

1 stop5h 01m

$250

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Sat 10/11

4:23 pm-11:55 pm

2 stops6h 32m

Greenville

Wed 10/15

5:36 pm-10:34 pm

1 stop5h 58m

$254

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Tue 10/7

6:00 am-12:47 pm

1 stop5h 47m

Greenville

Tue 10/14

5:30 am-11:45 am

2 stops7h 15m

$254

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Thu 9/25

1:33 pm-10:25 pm

1 stop7h 52m

Greenville

Mon 9/29

5:20 pm-10:56 pm

1 stop6h 36m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 48 results
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Best time to book a flight from Iowa to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Greenville

What is the cheapest month to book a flight from Iowa to Greenville?

Currently, August is the cheapest month in which you can book a flight from Iowa to Greenville (average of $322). Flying from Iowa to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to GSP?

Find hourly flight availability from Iowa to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Iowa to Greenville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Iowa?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Greenville.

  • How long is the flight from Iowa to Greenville?

    There are many flights that can get you from Iowa to Greenville in 4h 28m. Fly via American Airlines, United Airlines, or Delta to get the fastest option. There are 704 mi between Iowa and Greenville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Iowa to Greenville one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $110. Users have also found prices from $115 and $229 on United Airlines and Southwest, respectively.

  • What are the most popular routes from Iowa to Greenville?

    When deciding which route to take from Iowa to Greenville consider Des Moines - Greenville, Omaha Eppley Airfield - Greenville or Moline Quad-City - Greenville as they are the most popular.

  • Can I find deals for flights from Iowa to Greenville that include hotel bookings?

    Yes. In addition to deals on Iowa to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Greenville.

  • Can I find deals for business class flights from Iowa to Greenville?

    Yes. Cheapflights offers flight deals from Iowa to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Greenville (average of $322). Flying from Iowa to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 3 airlines flying from Iowa to Greenville

Discover the top 3 airlines that operate flights from Iowa to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$407FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$401FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$271Average$477FlexibilityNo cancel feeOn-time69%

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