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Florence

$269+ Cheap flights from Pennsylvania to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel.
PHL — FLO
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheap flight deals from Pennsylvania to Florence

Keep the following information in mind while searching for Pennsylvania to Florence flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$323
(American Airlines)

One-way from

$294
(American Airlines)
From Pennsylvania to Florence
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One-way flight from Pennsylvania to Florence
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Find flight deals from Pennsylvania to Florence

Cheapest flights from Pennsylvania to Florence
Explore the most affordable flight options available from Pennsylvania to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/2011:59 amDCA - FLO
1 stop5h 13mAmerican Airlines
lun. 9/226:14 amFLO - DCA
1 stop4h 45mAmerican Airlines
Deal found 9/13$269
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/207:17 pmIAD - FLO
1 stop3h 59mAmerican Airlines
lun. 9/226:14 amFLO - IAD
1 stop6h 04mAmerican Airlines
Deal found 9/13$269
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/3010:25 amIAD - FLO
1 stop4h 29mAmerican Airlines
vie. 11/286:33 pmFLO - IAD
1 stop5h 26mAmerican Airlines
Deal found 9/13$323
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/115:30 pmDCA - FLO
1 stop6h 33mAmerican Airlines
dom. 10/125:14 amFLO - DCA
1 stop4h 10mAmerican Airlines
Deal found 9/14$333
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/118:25 pmIAD - FLO
1 stop3h 38mAmerican Airlines
dom. 10/122:29 pmFLO - IAD
1 stop5h 16mAmerican Airlines
Deal found 9/14$333
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/3011:00 amLGA - FLO
1 stop6h 12mAmerican Airlines
sáb. 10/45:37 pmFLO - LGA
1 stop6h 08mAmerican Airlines
Deal found 9/15$361
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/3011:59 amJFK - FLO
1 stop5h 13mAmerican Airlines
sáb. 10/45:37 pmFLO - JFK
1 stop3h 59mAmerican Airlines
Deal found 9/15$361
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/305:39 pmEWR - FLO
1 stop5h 37mAmerican Airlines
sáb. 10/45:37 pmFLO - EWR
1 stop4h 23mAmerican Airlines
Deal found 9/15$361
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/157:51 amLGA - FLO
1 stop7h 03mAmerican Airlines
mié. 10/226:14 amFLO - LGA
1 stop4h 51mAmerican Airlines
Deal found 9/15$363
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/154:45 pmJFK - FLO
1 stop6h 28mAmerican Airlines
mar. 10/213:19 pmFLO - JFK
1 stop6h 40mAmerican Airlines
Deal found 9/15$363
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/118:25 pmIAD - FLO
1 stop3h 38mAmerican Airlines
lun. 10/135:14 amFLO - IAD
1 stop3h 35mAmerican Airlines
Deal found 9/14$363
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/155:28 pmLGA - FLO
1 stop5h 45mAmerican Airlines
mar. 10/216:14 amFLO - LGA
2 stops9h 12mAmerican Airlines
Deal found 9/15$368

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pennsylvania to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Pennsylvania to Florence that are best for you.

Fly from

Pennsylvania

Fly to

Florence

Route

Depart

Return

Price

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

jue. 10/30

10:25 am-2:54 pm

1 stop4h 29m

Florence

vie. 11/28

6:33 pm-11:59 pm

1 stop5h 26m

$323

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

mié. 10/15

10:25 am-2:54 pm

1 stop4h 29m

Florence

sáb. 10/18

2:29 pm-7:45 pm

1 stop5h 16m

$323

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

mar. 10/14

10:25 am-2:54 pm

1 stop4h 29m

Florence

mar. 10/21

6:14 am-9:55 am

1 stop3h 41m

$323

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

sáb. 10/11

5:30 pm-12:03 am

1 stop6h 33m

Florence

dom. 10/12

5:14 am-9:24 am

1 stop4h 10m

$333

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

sáb. 10/11

7:50 pm-12:03 am

1 stop4h 13m

Florence

lun. 10/13

5:14 am-9:24 am

1 stop4h 10m

$333

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

sáb. 10/11

8:25 pm-12:03 am

1 stop3h 38m

Florence

dom. 10/12

2:29 pm-7:45 pm

1 stop5h 16m

$333

NewarkFlorence

EWR - FLO

EWRFLO

Newark

mar. 9/30

5:39 pm-11:16 pm

1 stop5h 37m

Florence

sáb. 10/4

5:37 pm-10:00 pm

1 stop4h 23m

$361

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

mié. 10/15

7:51 am-2:54 pm

1 stop7h 03m

Florence

mié. 10/22

6:14 am-11:05 am

1 stop4h 51m

$363

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

sáb. 2/28

8:52 am-2:03 pm

1 stop5h 11m

Florence

lun. 3/2

11:11 am-3:58 pm

1 stop4h 47m

$363

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

sáb. 10/18

6:30 am-10:46 am

1 stop4h 16m

Florence

mié. 10/22

6:14 am-2:30 pm

2 stops8h 16m

$368

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 41 results
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Best time to book a flight from Pennsylvania to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Pennsylvania with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Florence

What is the cheapest month to book a flight from Pennsylvania to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Pennsylvania to Florence, South Carolina (average of $366). Flying from Pennsylvania to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to FLO?

Find hourly flight availability from Pennsylvania to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Pennsylvania to Florence, South Carolina as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Pennsylvania to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Pennsylvania?

    Most people fly into Florence (FLO) if they book a flight to Florence from Pennsylvania. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Pennsylvania to Florence, South Carolina?

    American Airlines can get you from Pennsylvania to Florence, South Carolina in just under 4h 29m. Your travel time can differ by up to . The distance between Pennsylvania and Florence, South Carolina is about 352 mi.

  • What are the most popular routes from Pennsylvania to Florence, South Carolina?

    The most popular flight routes from Pennsylvania to Florence, South Carolina are Newark - Florence, New York John F Kennedy Intl - Florence and New York LaGuardia - Florence.

  • Can I find deals for flights from Pennsylvania to Florence that include hotel bookings?

    Yes. In addition to deals on Pennsylvania to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pennsylvania to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Florence.

  • Can I find deals for business class flights from Pennsylvania to Florence?

    Yes. Cheapflights offers flight deals from Pennsylvania to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pennsylvania to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Pennsylvania to Florence, South Carolina (average of $366). Flying from Pennsylvania to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Alternative routes for Pennsylvania to Florence

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Pennsylvania to Florence

Discover the top airline that operate flights from Pennsylvania to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$345Average$542FlexibilityNo cancel feeOn-time71%

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