How long is the flight from Pennsylvania to Florence, South Carolina?

American Airlines can get you from Pennsylvania to Florence, South Carolina in just under 5h 47m. Your travel time can differ by up to . The distance between Pennsylvania and Florence, South Carolina is about 355 mi.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What are the most popular routes from Pennsylvania to Florence, South Carolina?

The most popular flight routes from Pennsylvania to Florence, South Carolina are New York John F Kennedy Intl - Florence, Newark - Florence and New York LaGuardia - Florence.

What airport do you fly into for flights to Florence from Pennsylvania?

Most people fly into Florence (FLO) if they book a flight to Florence from Pennsylvania. Florence is conveniently located just 2.3 mi from Florence’s city center.

Can I find deals for flights from Pennsylvania to Florence that include hotel bookings?

Yes. In addition to deals on Pennsylvania to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Pennsylvania to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Florence.

Can I find deals for business class flights from Pennsylvania to Florence?

Yes. Cheapflights offers flight deals from Pennsylvania to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$209+ Flights from Pennsylvania to Florence, SC

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Cheap flight deals from Pennsylvania to Florence

Cheapest flights from Pennsylvania to Florence
Explore the most affordable flight options available from Pennsylvania to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Wed 12/316:46 amDCA - FLO

1 stop5h 40mAmerican Airlines

Sun 1/45:15 amFLO - DCA

1 stop4h 05mAmerican Airlines

Deal found 12/21

$269

Wed 12/311:57 pmIAD - FLO

1 stop5h 41mAmerican Airlines

Sun 1/45:15 amFLO - IAD

1 stop3h 27mAmerican Airlines

Deal found 12/21

$269

Tue 12/306:35 amIAD - FLO

1 stop5h 51mAmerican Airlines

Thu 1/15:15 amFLO - IAD

1 stop3h 27mAmerican Airlines

Deal found 12/21

$299

Tue 12/307:15 pmLGA - FLO

1 stop5h 00mAmerican Airlines

Mon 1/56:30 pmFLO - LGA

1 stop4h 50mAmerican Airlines

Deal found 12/21

$304

Tue 12/306:30 amJFK - FLO

1 stop5h 56mAmerican Airlines

Mon 1/512:51 pmFLO - JFK

1 stop6h 38mAmerican Airlines

Deal found 12/21

$335

Tue 12/307:34 pmEWR - FLO

1 stop4h 41mAmerican Airlines

Mon 1/512:51 pmFLO - EWR

1 stop5h 53mAmerican Airlines

Deal found 12/21

$335

Wed 12/316:00 amLGA - FLO

1 stop6h 26mAmerican Airlines

Sun 1/46:30 pmFLO - LGA

1 stop4h 04mAmerican Airlines

Deal found 12/21

$351

Wed 12/316:10 amEWR - FLO

1 stop6h 16mAmerican Airlines

Wed 1/75:36 pmFLO - EWR

1 stop4h 24mAmerican Airlines

Deal found 12/22

$351

Wed 12/318:00 amEWR - FLO

1 stop4h 26mAmerican Airlines

Fri 1/25:15 amFLO - EWR

1 stop4h 23mAmerican Airlines

Deal found 12/22

$386

Wed 12/316:00 amLGA - FLO

1 stop6h 26mAmerican Airlines

Sat 1/35:15 amFLO - LGA

1 stop3h 59mAmerican Airlines

Deal found 12/21

$417

Fri 12/267:50 pmDCA - FLO

1 stop4h 25mAmerican Airlines

Sun 12/286:30 pmFLO - DCA

1 stop5h 18mAmerican Airlines

Deal found 12/22

$419

Fri 12/261:57 pmIAD - FLO

1 stop4h 08mAmerican Airlines

Sun 12/285:15 amFLO - IAD

1 stop3h 27mAmerican Airlines

Deal found 12/22

$419

Best flights from Pennsylvania to Florence
Discover carefully curated flight deals from Pennsylvania to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.

Sat 1/175:24 pmDCA - FLO

1 stop5h 47mAmerican Airlines

Sat 1/246:15 amFLO - DCA

1 stop4h 35mAmerican Airlines

Deal found 12/19

$209

Wed 2/1110:09 amLGA - FLO

1 stop7h 00mAmerican Airlines

Sat 2/146:18 pmFLO - LGA

1 stop5h 18mAmerican Airlines

Deal found 12/21

$229

Wed 2/1110:09 amLGA - FLO

1 stop7h 00mAmerican Airlines

Wed 2/186:15 amFLO - LGA

1 stop5h 44mAmerican Airlines

Deal found 12/21

$229

Fri 1/1612:40 pmLGA - FLO

1 stop4h 29mAmerican Airlines

Wed 1/215:36 pmFLO - LGA

1 stop3h 49mAmerican Airlines

Deal found 12/21

$229

Wed 1/145:16 pmLGA - FLO

1 stop5h 27mAmerican Airlines

Sat 1/175:36 pmFLO - LGA

1 stop3h 49mAmerican Airlines

Deal found 12/21

$229

Wed 1/1411:21 amJFK - FLO

1 stop5h 48mAmerican Airlines

Sat 1/176:15 amFLO - JFK

1 stop4h 17mAmerican Airlines

Deal found 12/21

$229

Wed 2/1111:21 amJFK - FLO

1 stop5h 48mAmerican Airlines

Wed 2/186:15 amFLO - JFK

1 stop3h 45mAmerican Airlines

Deal found 12/21

$229

Fri 1/2311:21 amJFK - FLO

1 stop5h 48mAmerican Airlines

Mon 1/265:36 pmFLO - JFK

1 stop4h 47mAmerican Airlines

Deal found 12/22

$229

Fri 1/169:59 amEWR - FLO

1 stop7h 10mAmerican Airlines

Wed 1/216:15 amFLO - EWR

1 stop6h 35mAmerican Airlines

Deal found 12/21

$229

Fri 1/235:16 pmLGA - FLO

1 stop5h 27mAmerican Airlines

Mon 1/266:15 amFLO - LGA

2 stops9h 14mAmerican Airlines

Deal found 12/22

$234

Sat 1/1712:10 pmJFK - FLO

2 stops11h 01mAmerican Airlines

Mon 1/196:15 amFLO - JFK

1 stop4h 16mAmerican Airlines

Deal found 12/21

$234

Wed 2/118:25 amJFK - FLO

2 stops8h 44mAmerican Airlines

Sat 2/145:15 amFLO - JFK

1 stop4h 44mAmerican Airlines

Deal found 12/21

$234

Tue 1/65:24 pmDCA - FLO

1 stop5h 19mAmerican Airlines

Sat 1/105:36 pmFLO - DCA

1 stop5h 58mAmerican Airlines

Deal found 12/22

$239

Tue 1/611:34 amIAD - FLO

1 stop5h 35mAmerican Airlines

Sat 1/105:36 pmFLO - IAD

1 stop6h 06mAmerican Airlines

Deal found 12/22

$239

Wed 12/316:46 amDCA - FLO

1 stop5h 40mAmerican Airlines

Sun 1/45:15 amFLO - DCA

1 stop4h 05mAmerican Airlines

Deal found 12/21

$269

Tue 1/65:20 pmEWR - FLO

1 stop5h 23mAmerican Airlines

Sat 1/106:15 amFLO - EWR

1 stop6h 35mAmerican Airlines

Deal found 12/22

$269

Tue 2/175:12 pmEWR - FLO

1 stop6h 00mAmerican Airlines

Fri 2/276:18 pmFLO - EWR

1 stop4h 08mAmerican Airlines

Deal found 12/22

$299

Mon 2/231:30 pmEWR - FLO

1 stop4h 15mAmerican Airlines

Tue 3/36:15 amFLO - EWR

1 stop6h 15mAmerican Airlines

Deal found 12/22

$299

Wed 2/181:30 pmEWR - FLO

1 stop3h 53mAmerican Airlines

Thu 2/265:15 amFLO - EWR

1 stop4h 15mAmerican Airlines

Deal found 12/22

$299

Thu 1/17:34 pmEWR - FLO

1 stop4h 41mAmerican Airlines

Tue 1/65:36 pmFLO - EWR

1 stop4h 24mAmerican Airlines

Deal found 12/22

$351

Wed 12/316:10 amEWR - FLO

1 stop6h 16mAmerican Airlines

Thu 1/85:36 pmFLO - EWR

1 stop4h 24mAmerican Airlines

Deal found 12/22

$351

Thu 1/18:00 amEWR - FLO

1 stop4h 26mAmerican Airlines

Wed 1/76:15 amFLO - EWR

1 stop6h 35mAmerican Airlines

Deal found 12/22

$351

Fri 1/28:00 amEWR - FLO

1 stop4h 42mAmerican Airlines

Thu 1/86:15 amFLO - EWR

1 stop6h 35mAmerican Airlines

Deal found 12/22

$374

Fri 1/28:00 amEWR - FLO

1 stop4h 42mAmerican Airlines

Tue 1/65:36 pmFLO - EWR

1 stop4h 24mAmerican Airlines

Deal found 12/22

$374

Sat 1/37:30 pmEWR - FLO

1 stop4h 45mAmerican Airlines

Tue 1/65:36 pmFLO - EWR

1 stop4h 24mAmerican Airlines

Deal found 12/22

$374

Thu 1/17:34 pmEWR - FLO

1 stop4h 41mAmerican Airlines

Fri 1/25:15 amFLO - EWR

1 stop4h 23mAmerican Airlines

Deal found 12/22

$386

Fri 12/267:50 pmDCA - FLO

1 stop4h 25mAmerican Airlines

Sun 12/286:30 pmFLO - DCA

1 stop5h 18mAmerican Airlines

Deal found 12/22

$419

Wed 1/216:55 pmPHL - FLO

1 stop3h 48mAmerican Airlines

Sat 1/245:36 pmFLO - PHL

1 stop3h 42mAmerican Airlines

Deal found 12/21

$463

Sat 1/317:24 pmPHL - FLO

1 stop3h 47mAmerican Airlines

Tue 2/35:36 pmFLO - PHL

1 stop3h 29mAmerican Airlines

Deal found 12/21

$463

Sat 1/247:24 pmPHL - FLO

1 stop3h 47mAmerican Airlines

Tue 1/275:36 pmFLO - PHL

1 stop3h 29mAmerican Airlines

Deal found 12/21

$463

Last-minute flights from Pennsylvania to Florence
Discover last-minute flight deals from Pennsylvania to Florence. Data last updated December 23, 2025 and is based on user searches.

Tue 12/306:35 amIAD - FLO

1 stop5h 51mAmerican Airlines

Thu 1/15:15 amFLO - IAD

1 stop3h 27mAmerican Airlines

Deal found 12/21

$299

Wed 12/316:46 amDCA - FLO

1 stop5h 40mAmerican Airlines

Sun 1/45:15 amFLO - DCA

1 stop4h 05mAmerican Airlines

Deal found 12/21

$269

Wed 12/311:57 pmIAD - FLO

1 stop5h 41mAmerican Airlines

Sun 1/45:15 amFLO - IAD

1 stop3h 27mAmerican Airlines

Deal found 12/21

$269

Tue 1/65:24 pmDCA - FLO

1 stop5h 19mAmerican Airlines

Sat 1/105:36 pmFLO - DCA

1 stop5h 58mAmerican Airlines

Deal found 12/22

$239

Tue 1/611:34 amIAD - FLO

1 stop5h 35mAmerican Airlines

Sat 1/105:36 pmFLO - IAD

1 stop6h 06mAmerican Airlines

Deal found 12/22

$239

Tue 1/66:47 pmLGA - FLO

1 stop3h 56mAmerican Airlines

Sat 1/106:15 amFLO - LGA

1 stop5h 40mAmerican Airlines

Deal found 12/22

$269

Tue 1/611:21 amJFK - FLO

1 stop5h 48mAmerican Airlines

Sat 1/106:15 amFLO - JFK

1 stop4h 17mAmerican Airlines

Deal found 12/22

$269

Tue 1/65:20 pmEWR - FLO

1 stop5h 23mAmerican Airlines

Sat 1/106:15 amFLO - EWR

1 stop6h 35mAmerican Airlines

Deal found 12/22

$269

Wed 1/145:16 pmLGA - FLO

1 stop5h 27mAmerican Airlines

Sat 1/175:36 pmFLO - LGA

1 stop3h 49mAmerican Airlines

Deal found 12/21

$229

Wed 1/1411:21 amJFK - FLO

1 stop5h 48mAmerican Airlines

Sat 1/176:15 amFLO - JFK

1 stop4h 17mAmerican Airlines

Deal found 12/22

$229

Fri 1/169:59 amEWR - FLO

1 stop7h 10mAmerican Airlines

Wed 1/216:15 amFLO - EWR

1 stop6h 35mAmerican Airlines

Deal found 12/21

$229

Sat 1/175:24 pmDCA - FLO

1 stop5h 47mAmerican Airlines

Sat 1/246:15 amFLO - DCA

1 stop4h 35mAmerican Airlines

Deal found 12/19

$209

One-way flights from Pennsylvania to Florence
Search for one-way flight options from Pennsylvania to Florence. Find affordable one-way fares based on user searches. Data last updated December 23, 2025.

Tue 12/301:46 pmLGA - FLO

1 stop4h 19mAmerican Airlines

Deal found 12/22

$347

Tue 12/308:00 amJFK - FLO

1 stop4h 26mAmerican Airlines

Deal found 12/22

$347

Tue 12/306:10 amEWR - FLO

1 stop6h 16mAmerican Airlines

Deal found 12/22

$347

Tue 5/125:51 pmABE - FLO

1 stop5h 50mAmerican Airlines

Deal found 12/21

$384

Mon 12/297:59 amLGA - FLO

1 stop4h 27mAmerican Airlines

Deal found 12/22

$424

Mon 12/2911:29 amJFK - FLO

1 stop6h 36mAmerican Airlines

Deal found 12/22

$424

Mon 12/296:10 amEWR - FLO

1 stop6h 16mAmerican Airlines

Deal found 12/22

$424

Find flight deals from Pennsylvania to Florence

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$229 (American Airlines)

Provider with most accurate pricing for Philadelphia-Florence flight deals.

Search Deals

Provider most trusted by Cheapflights users for Philadelphia-Florence flights.

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From Pennsylvania to Florence

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Pennsylvania to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 1/17

5:24 pm-11:11 pm

1 stop5h 47m

Florence

Sat 1/24

6:15 am-10:50 am

1 stop4h 35m

$209

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 2/11

10:09 am-5:09 pm

1 stop7h 00m

Florence

Sat 2/14

6:18 pm-11:36 pm

1 stop5h 18m

$229

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 2/11

10:09 am-5:09 pm

1 stop7h 00m

Florence

Wed 2/18

6:15 am-11:59 am

1 stop5h 44m

$229

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 1/16

12:40 pm-5:09 pm

1 stop4h 29m

Florence

Wed 1/21

5:36 pm-9:25 pm

1 stop3h 49m

$229

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 1/14

5:16 pm-10:43 pm

1 stop5h 27m

Florence

Sat 1/17

5:36 pm-9:25 pm

1 stop3h 49m

$229

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Wed 1/14

11:21 am-5:09 pm

1 stop5h 48m

Florence

Sat 1/17

6:15 am-10:32 am

1 stop4h 17m

$229

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Wed 2/11

11:21 am-5:09 pm

1 stop5h 48m

Florence

Wed 2/18

6:15 am-10:00 am

1 stop3h 45m

$229

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Fri 1/23

11:21 am-5:09 pm

1 stop5h 48m

Florence

Mon 1/26

5:36 pm-10:23 pm

1 stop4h 47m

$229

NewarkFlorence

EWR - FLO

EWRFLO

Newark

Fri 1/16

9:59 am-5:09 pm

1 stop7h 10m

Florence

Wed 1/21

6:15 am-12:50 pm

1 stop6h 35m

$229

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 1/23

5:16 pm-10:43 pm

1 stop5h 27m

Florence

Mon 1/26

6:15 am-3:29 pm

2 stops9h 14m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 37 results

Best time to book a flight from Pennsylvania to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Pennsylvania with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Florence

What is the cheapest month to book a flight from Pennsylvania to Florence, South Carolina?

Currently, February is the cheapest month in which you can book a flight from Pennsylvania to Florence, South Carolina (average of $38). Flying from Pennsylvania to Florence, South Carolina in June is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to FLO?

When flying from Pennsylvania to Florence, South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 25% versus a flight at noon.

Related info for your journey

What airport do you fly into for flights to Florence from Pennsylvania?
Most people fly into Florence (FLO) if they book a flight to Florence from Pennsylvania. Florence is conveniently located just 2.3 mi from Florence’s city center.
How long is the flight from Pennsylvania to Florence, South Carolina?
American Airlines can get you from Pennsylvania to Florence, South Carolina in just under 5h 47m. Your travel time can differ by up to . The distance between Pennsylvania and Florence, South Carolina is about 355 mi.
What are the most popular routes from Pennsylvania to Florence, South Carolina?
The most popular flight routes from Pennsylvania to Florence, South Carolina are New York John F Kennedy Intl - Florence, Newark - Florence and New York LaGuardia - Florence.
Can I find deals for flights from Pennsylvania to Florence that include hotel bookings?
Yes. In addition to deals on Pennsylvania to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Pennsylvania to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Florence.
Can I find deals for business class flights from Pennsylvania to Florence?
Yes. Cheapflights offers flight deals from Pennsylvania to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Pennsylvania to Florence, South Carolina?
Currently, February is the cheapest month in which you can book a flight from Pennsylvania to Florence, South Carolina (average of $38). Flying from Pennsylvania to Florence, South Carolina in June is currently the most expensive (average of $90). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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$209+ Cheap flights from Pennsylvania to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Pennsylvania to Florence with Cheapflights

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Cheap flight deals from Pennsylvania to Florence

Cheapest flights from Pennsylvania to FlorenceExplore the most affordable flight options available from Pennsylvania to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Explore the most affordable flight options available from Pennsylvania to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Find flight deals from Pennsylvania to Florence

Keep the following information in mind while searching for Pennsylvania to Florence flight deals. Data was last updated December 23, 2025.

Most accurate provider

Most trusted provider

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Pennsylvania to Florence that are best for you.

Best time to book a flight from Pennsylvania to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Pennsylvania with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Florence

What is the cheapest month to book a flight from Pennsylvania to Florence, South Carolina?

What is the cheapest time of day to fly from PA to FLO?

Find hourly flight availability from Pennsylvania to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

Related info for your journey

Find useful and relevant information for your journey from Pennsylvania to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Florence from Pennsylvania?

How long is the flight from Pennsylvania to Florence, South Carolina?

What are the most popular routes from Pennsylvania to Florence, South Carolina?

Can I find deals for flights from Pennsylvania to Florence that include hotel bookings?

How can I find direct flights from Pennsylvania to Florence?

Can I find deals for business class flights from Pennsylvania to Florence?

What is the cheapest month to book a flight from Pennsylvania to Florence, South Carolina?

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Cheapest flights from Pennsylvania to Florence
Explore the most affordable flight options available from Pennsylvania to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.