Florence

$209+ Cheap flights from Pennsylvania to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
PHL — FLO
Mar 19 — Mar 261
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Cheap flight deals from Pennsylvania to Florence

Cheapest flights from Pennsylvania to Florence
Explore the most affordable flight options available from Pennsylvania to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 17, 2026.

This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/145:24 pm
DCA
-
FLO
1 stop6h 33m
American Airlines
Wed 3/185:16 am
FLO
-
DCA
1 stop4h 12m
American Airlines
Deal found 2/14$209
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:32 pm
JFK
-
FLO
1 stop4h 25m
American Airlines
Wed 3/255:16 am
FLO
-
JFK
1 stop4h 58m
American Airlines
Deal found 2/16$229
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:41 pm
DCA
-
FLO
1 stop4h 16m
American Airlines
Wed 3/45:58 pm
FLO
-
DCA
1 stop6h 01m
American Airlines
Deal found 2/13$239
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:03 pm
IAD
-
FLO
1 stop3h 47m
American Airlines
Wed 3/46:15 am
FLO
-
IAD
1 stop4h 45m
American Airlines
Deal found 2/13$239
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:29 pm
JFK
-
FLO
1 stop4h 23m
American Airlines
Sat 5/164:16 pm
FLO
-
JFK
1 stop6h 00m
American Airlines
Deal found 2/16$262
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:26 pm
EWR
-
FLO
1 stop4h 27m
American Airlines
Sat 5/165:24 am
FLO
-
EWR
1 stop4h 16m
American Airlines
Deal found 2/13$262
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:59 am
JFK
-
FLO
1 stop6h 51m
American Airlines
Wed 3/46:15 am
FLO
-
JFK
1 stop3h 54m
American Airlines
Deal found 2/13$269
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:16 pm
EWR
-
FLO
1 stop6h 41m
American Airlines
Wed 3/45:58 pm
FLO
-
EWR
1 stop4h 31m
American Airlines
Deal found 2/13$269
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:59 pm
LGA
-
FLO
1 stop4h 58m
American Airlines
Wed 3/46:15 am
FLO
-
LGA
1 stop4h 48m
American Airlines
Deal found 2/13$279
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:30 am
JFK
-
FLO
1 stop4h 15m
American Airlines
Thu 11/1211:11 am
FLO
-
JFK
1 stop3h 45m
American Airlines
Deal found 2/15$301
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:44 pm
EWR
-
FLO
1 stop4h 23m
American Airlines
Thu 11/1211:11 am
FLO
-
EWR
1 stop5h 26m
American Airlines
Deal found 2/15$301
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:15 am
LGA
-
FLO
1 stop7h 06m
American Airlines
Sun 3/15:16 am
FLO
-
LGA
1 stop5h 44m
American Airlines
Deal found 2/15$304

Find flight deals from Pennsylvania to Florence

Keep the following information in mind while searching for Pennsylvania to Florence flight deals. Data was last updated February 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$209
(American Airlines)
Provider with most accurate pricing for Philadelphia-Florence flight deals.
Provider most trusted by Cheapflights users for Philadelphia-Florence flights.
From Pennsylvania to Florence

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pennsylvania to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
Use the filters below to find and compare flights from Pennsylvania to Florence that are best for you.

Fly from

Pennsylvania

Fly to

Florence

Route

Depart

Return

Price

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 3/14

5:24 pm-11:57 pm

1 stop6h 33m

Florence

Wed 3/18

5:16 am-9:28 am

1 stop4h 12m

$209

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Wed 3/18

7:32 pm-11:57 pm

1 stop4h 25m

Florence

Wed 3/25

5:16 am-10:14 am

1 stop4h 58m

$229

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 2/28

7:41 pm-11:57 pm

1 stop4h 16m

Florence

Wed 3/4

5:58 pm-11:59 pm

1 stop6h 01m

$239

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Sat 2/28

2:03 pm-5:50 pm

1 stop3h 47m

Florence

Wed 3/4

6:15 am-11:00 am

1 stop4h 45m

$239

NewarkFlorence

EWR - FLO

EWRFLO

Newark

Sat 5/9

7:26 pm-11:53 pm

1 stop4h 27m

Florence

Sat 5/16

5:24 am-9:40 am

1 stop4h 16m

$262

New YorkFlorence

JFK - FLO

JFKFLO

New York John F Kennedy Intl

Sat 2/28

10:59 am-5:50 pm

1 stop6h 51m

Florence

Wed 3/4

6:15 am-10:09 am

1 stop3h 54m

$269

NewarkFlorence

EWR - FLO

EWRFLO

Newark

Sat 2/28

5:16 pm-11:57 pm

1 stop6h 41m

Florence

Wed 3/4

5:58 pm-10:29 pm

1 stop4h 31m

$269

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 2/28

6:59 pm-11:57 pm

1 stop4h 58m

Florence

Wed 3/4

6:15 am-11:03 am

1 stop4h 48m

$279

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 2/27

5:23 pm-11:57 pm

1 stop6h 34m

Florence

Sun 3/1

5:16 am-11:00 am

1 stop5h 44m

$304

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 2/26

12:48 pm-5:50 pm

1 stop5h 02m

Florence

Sun 3/1

5:16 am-11:00 am

1 stop5h 44m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/14

Showing 1-10 of 50 results
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Best time to book a flight from Pennsylvania to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Pennsylvania with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Florence

What is the cheapest month to book a flight from Pennsylvania to Florence, South Carolina?

Currently, September is the cheapest month in which you can book a flight from Pennsylvania to Florence, South Carolina (average of $52). Flying from Pennsylvania to Florence, South Carolina in June is currently the most expensive (average of $88). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Pennsylvania to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Florence from Pennsylvania?

    Most people fly into Florence (FLO) if they book a flight to Florence from Pennsylvania. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Pennsylvania to Florence, South Carolina?

    American Airlines can get you from Pennsylvania to Florence, South Carolina in just under 6h 33m. Your travel time can differ by up to . The distance between Pennsylvania and Florence, South Carolina is about 355 mi.

  • What are the most popular routes from Pennsylvania to Florence, South Carolina?

  • Can I find deals for flights from Pennsylvania to Florence that include hotel bookings?

    Yes. In addition to deals on Pennsylvania to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pennsylvania to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Florence.

  • Can I find deals for business class flights from Pennsylvania to Florence?

    Yes. Cheapflights offers flight deals from Pennsylvania to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pennsylvania to Florence, South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Pennsylvania to Florence, South Carolina (average of $52). Flying from Pennsylvania to Florence, South Carolina in June is currently the most expensive (average of $88). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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