HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$289+ Cheap flights from LaGuardia, NY (LGA) to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — FLO
May 4 — May 111
Mon 5/4
Mon 5/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from LaGuardia to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from LaGuardia to Florence

Cheapest flights from LaGuardia to Florence
Explore the most affordable flight options available from LaGuardia to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2026.

This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:12 am
LGA
-
FLO
1 stop5h 20m
American Airlines
Tue 5/56:15 am
FLO
-
LGA
1 stop6h 44m
American Airlines
Deal found 3/31$289
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:23 pm
LGA
-
FLO
1 stop5h 19m
American Airlines
Sat 4/185:20 am
FLO
-
LGA
1 stop3h 59m
American Airlines
Deal found 3/30$329
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:30 pm
LGA
-
FLO
2 stops8h 30m
American Airlines
Thu 6/112:35 pm
FLO
-
LGA
1 stop3h 52m
American Airlines
Deal found 4/2$380
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:05 pm
LGA
-
FLO
1 stop6h 42m
American Airlines
Tue 5/194:02 pm
FLO
-
LGA
1 stop3h 57m
American Airlines
Deal found 4/1$433
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:23 pm
LGA
-
FLO
1 stop4h 24m
American Airlines
Sun 5/35:20 am
FLO
-
LGA
1 stop4h 01m
American Airlines
Deal found 4/2$440
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:50 am
LGA
-
FLO
2 stops8h 00m
American Airlines
Sat 5/95:20 am
FLO
-
LGA
2 stops6h 10m
American Airlines
Deal found 3/31$451

Find flight deals from LaGuardia to Florence

Discover tips and strategies to find the most affordable flight options for your journey from LaGuardia (LGA) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(American Airlines)

Popular in

November

Cheapest in

October

Average price

$392
Provider with most accurate pricing for New York LaGuardia-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York LaGuardia-Florence flights.
Search Deals
From New York LaGuardia to Florence
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from LaGuardia to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Tue 4/28

10:12 am-3:32 pm

1 stop5h 20m

Florence

Tue 5/5

6:15 am-12:59 pm

1 stop6h 44m

$289

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 4/29

3:04 pm-9:47 pm

1 stop6h 43m

Florence

Wed 5/6

5:20 am-1:59 pm

2 stops8h 39m

$294

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Tue 4/14

7:50 am-3:32 pm

2 stops7h 42m

Florence

Sat 4/18

4:16 pm-7:59 pm

1 stop3h 43m

$334

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 4/30

7:50 am-3:50 pm

2 stops8h 00m

Florence

Sat 5/9

5:20 am-11:05 am

1 stop5h 45m

$445

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Tue 6/30

5:00 pm-10:00 pm

1 stop5h 00m

Florence

Wed 7/8

2:35 pm-7:45 pm

1 stop5h 10m

$487

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 7/1

6:15 am-2:10 pm

2 stops7h 55m

Florence

Wed 7/8

2:35 pm-7:45 pm

1 stop5h 10m

$492

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 4/25

12:10 pm-9:47 pm

2 stops9h 37m

Florence

Wed 4/29

5:20 am-11:29 am

2 stops6h 09m

$493
Quickest round-trip

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 7/2

7:55 am-2:10 pm

1 stop6h 15m

Florence

Wed 7/8

2:35 pm-6:29 pm

1 stop3h 54m

$565
Cheapest one-way

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 4/17

10:11 am-3:50 pm

1 stop5h 39m

$464
Quickest one-way

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 4/16

10:12 am-3:50 pm

1 stop5h 38m

$464

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Sorted by cheapest first

Compare providers for flights from LaGuardia to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from LaGuardia to Florence in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on New York LaGuardia Airport-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on New York LaGuardia Airport-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from New York LaGuardia Airport-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on New York LaGuardia Airport-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New York LaGuardia Airport-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from LaGuardia to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from LaGuardia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New York LaGuardia Airport to Florence

What is the cheapest month to book a flight from New York LaGuardia Airport to Florence, South Carolina?

Currently, April is the cheapest month in which you can book a flight from New York LaGuardia Airport to Florence, South Carolina (average of $46). Flying from New York LaGuardia Airport to Florence, South Carolina in June is currently the most expensive (average of $100). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated April 4, 2026.
Read reviews from past customers who have flown American Airlines from New York LaGuardia Airport to Florence. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,559 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Overall

7.1

Crew

7.9

Food

6.4

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,559 reviews
American Airlines
7.1
Good
11,559 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Overall

7.1

Crew

7.9

Food

6.4

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from LaGuardia to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from New York LaGuardia?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly into when you book flights from New York LaGuardia to Florence. 1 airline have flights to Florence from New York LaGuardia on a regular basis. Booking flights from New York LaGuardia to Florence should not be difficult; the airport handles an average of 0 inbound flights from New York LaGuardia per day.

  • How long is the flight from New York LaGuardia Airport to Florence, South Carolina?

    Airlines like American Airlines fly from New York LaGuardia Airport to Florence, South Carolina in about 5h 20m. The time it takes to get you to your destination can typically vary by up to . There are 556 mi between New York LaGuardia Airport and Florence, South Carolina.

  • What is the cheapest airline to fly from New York LaGuardia Airport to Florence, South Carolina round-trip?

    According to our current data, American Airlines ($292), offers the cheapest pricing from New York LaGuardia Airport to Florence, South Carolina.

  • Can I find deals for flights from LaGuardia to Florence that include hotel bookings?

    Yes. In addition to deals on LaGuardia to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from LaGuardia to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from LaGuardia to Florence.

  • Can I find deals for business class flights from LaGuardia to Florence?

    Yes. Cheapflights offers flight deals from LaGuardia to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New York LaGuardia Airport to Florence, South Carolina?

    Currently, April is the cheapest month in which you can book a flight from New York LaGuardia Airport to Florence, South Carolina (average of $46). Flying from New York LaGuardia Airport to Florence, South Carolina in June is currently the most expensive (average of $100). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from LaGuardia to Florence

Discover the top airline that operate flights from LaGuardia to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$292Average$454FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.