$333+ Cheap flights from LaGuardia, NY (LGA) to Florence, SC (FLO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — FLO
Sep 16 — Sep 231
Round-trip
1 adult, Economy
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Find cheap flights from LaGuardia to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from LaGuardia to Florence
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Best
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Cheapest flights from LaGuardia to FlorenceExplore the most affordable flight options available from LaGuardia to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
Explore the most affordable flight options available from LaGuardia to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:59 pm -
1 stop5h 59m
Wed 9/161:43 pm -
1 stop6h 09m
Deal found 8/17![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:29 am -
1 stop6h 40m
Sun 12/65:09 am -
1 stop3h 53m
Deal found 8/14![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:29 pm -
1 stop4h 43m
Sun 11/12:35 pm -
1 stop3h 54m
Deal found 8/12![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:29 am -
1 stop4h 40m
Sat 12/53:37 pm -
1 stop4h 23m
Deal found 8/14![American Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:59 am -
1 stop5h 19m
Wed 9/301:43 pm -
1 stop6h 09m
Deal found 8/13![American Airlines logo]()
$443
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:00 pm -
1 stop5h 59m
Wed 9/26:22 am -
1 stop5h 04m
Deal found 8/14![American Airlines logo]()
$471
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:30 pm -
1 stop4h 28m
Thu 10/11:43 pm -
1 stop3h 57m
Deal found 8/13![American Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:13 pm -
1 stop5h 41m
Tue 12/83:44 pm -
1 stop4h 16m
Deal found 8/14![American Airlines logo]()
$499
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:59 pm -
1 stop5h 59m
Tue 9/291:43 pm -
1 stop3h 48m
Deal found 8/13![American Airlines logo]()
$500
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:29 am -
1 stop6h 40m
Wed 12/93:37 pm -
1 stop4h 23m
Deal found 8/14![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:59 am -
1 stop4h 57m
Sat 8/293:22 pm -
1 stop4h 37m
Deal found 8/15![American Airlines logo]()
$551
Best flights from LaGuardia to FlorenceDiscover carefully curated flight deals from LaGuardia to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
Discover carefully curated flight deals from LaGuardia to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 17, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:59 pm -
1 stop5h 59m
Wed 9/161:43 pm -
1 stop6h 09m
Deal found 8/17![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:29 pm -
1 stop4h 43m
Sun 11/12:35 pm -
1 stop3h 54m
Deal found 8/12![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:13 pm -
1 stop4h 46m
Sun 12/65:09 am -
1 stop3h 53m
Deal found 8/14![American Airlines logo]()
$499
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:59 pm -
1 stop5h 59m
Tue 9/291:43 pm -
1 stop3h 48m
Deal found 8/13![American Airlines logo]()
$500
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:00 pm -
1 stop6h 56m
Sun 12/65:09 am -
1 stop6h 14m
Deal found 8/14![American Airlines logo]()
$556
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:59 am -
1 stop5h 19m
Sun 10/45:09 am -
1 stop3h 55m
Deal found 8/16![American Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:30 pm -
1 stop4h 28m
Sun 10/45:09 am -
1 stop3h 55m
Deal found 8/16![American Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:59 am -
1 stop4h 57m
Sun 9/62:37 pm -
1 stop3h 49m
Deal found 8/12![American Airlines logo]()
$621
Last-minute flights from LaGuardia to FlorenceDiscover last-minute flight deals from LaGuardia to Florence. Data last updated August 17, 2026 and is based on user searches.
Discover last-minute flight deals from LaGuardia to Florence. Data last updated August 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:59 am -
1 stop4h 57m
Fri 8/283:22 pm -
1 stop4h 37m
Deal found 8/15![American Airlines logo]()
$586
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:59 am -
1 stop4h 57m
Sat 8/293:22 pm -
1 stop4h 37m
Deal found 8/15![American Airlines logo]()
$551
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:55 am -
1 stop7h 01m
Mon 8/313:22 pm -
1 stop4h 37m
Deal found 8/13![American Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:00 pm -
1 stop5h 59m
Wed 9/26:22 am -
1 stop5h 04m
Deal found 8/14![American Airlines logo]()
$471
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/62:29 pm -
1 stop6h 51m
Tue 9/151:43 pm -
2 stops7h 16m
Deal found 8/14![American Airlines logo]()
$572
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:59 pm -
1 stop5h 59m
Wed 9/161:43 pm -
1 stop6h 09m
Deal found 8/17![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:59 pm -
1 stop5h 59m
Tue 9/291:43 pm -
1 stop3h 48m
Deal found 8/13![American Airlines logo]()
$500
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:59 am -
1 stop5h 19m
Fri 10/21:43 pm -
1 stop3h 48m
Deal found 8/13![American Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:30 pm -
1 stop4h 28m
Thu 10/11:43 pm -
1 stop3h 57m
Deal found 8/13![American Airlines logo]()
$477
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:59 am -
1 stop5h 19m
Wed 9/301:43 pm -
1 stop6h 09m
Deal found 8/13![American Airlines logo]()
$443
One-way flights from LaGuardia to FlorenceSearch for one-way flight options from LaGuardia to Florence. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
Search for one-way flight options from LaGuardia to Florence. Find affordable one-way fares based on user searches. Data last updated August 17, 2026.
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:25 pm -
2 stops11h 32m
Deal found 8/13![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:59 am -
2 stops15h 59m
Deal found 8/16![American Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:59 am -
2 stops16h 58m
Deal found 8/16![American Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:08 pm -
2 stops7h 51m
Deal found 8/15![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:59 am -
2 stops14h 59m
Deal found 8/16![American Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:59 pm -
1 stop5h 59m
Deal found 8/13![American Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
2 stops16h 58m
Deal found 8/16![American Airlines logo]()
$489
Find flight deals from LaGuardia to Florence
Discover tips and strategies to find the most affordable flight options for your journey from LaGuardia (LGA) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $363 (American Airlines) |
One-way from | $333 (American Airlines) |
Popular in | March |
Cheapest in | June |
Average price | $592 |
Cheapflights Fare Finder
Customize your flight search to find flights from LaGuardia to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Wed 9/9
4:59 pm-10:58 pm
1 stop5h 59m
Florence
Wed 9/16
1:43 pm-7:52 pm
1 stop6h 09m
$363
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Tue 10/27
6:29 pm-11:12 pm
1 stop4h 43m
Florence
Sun 11/1
2:35 pm-6:29 pm
1 stop3h 54m
$420
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Wed 12/2
6:13 pm-10:59 pm
1 stop4h 46m
Florence
Sun 12/6
5:09 am-9:02 am
1 stop3h 53m
$499
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Thu 9/17
4:59 pm-10:58 pm
1 stop5h 59m
Florence
Tue 9/29
1:43 pm-5:31 pm
1 stop3h 48m
$500
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Fri 12/4
5:00 pm-11:56 pm
1 stop6h 56m
Florence
Sun 12/6
5:09 am-11:23 am
1 stop6h 14m
$556
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Thu 10/1
7:59 am-1:18 pm
1 stop5h 19m
Florence
Sun 10/4
5:09 am-9:04 am
1 stop3h 55m
$557
Quickest round-trip
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Fri 10/2
6:30 pm-10:58 pm
1 stop4h 28m
Florence
Sun 10/4
5:09 am-9:04 am
1 stop3h 55m
$557
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Mon 8/31
9:59 am-2:56 pm
1 stop4h 57m
Florence
Sun 9/6
2:37 pm-6:26 pm
1 stop3h 49m
$621
Cheapest one-way
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Sat 10/10
12:25 pm-11:57 pm
2 stops11h 32m
$333
New YorkFlorence
LGA New York LaGuardia - FLO Florence
LGAFLO
New York LaGuardia
Sat 9/19
6:59 am-10:58 pm
2 stops15h 59m
$377
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from LaGuardia to Florence
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from LaGuardia to Florence in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on New York LaGuardia Airport-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on New York LaGuardia Airport-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from New York LaGuardia Airport-Florence, South Carolina flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on New York LaGuardia Airport-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New York LaGuardia Airport-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from LaGuardia to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from LaGuardia with our price prediction graph.
LGA-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Florence
Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated August 17, 2026.
Read reviews from past customers who have flown American Airlines from New York LaGuardia Airport to Florence. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Crew
7.9
Entertainment
6.8
Comfort
7.2
Overall
7.1
Boarding
7.5
Reviews
1 / 20
2.0
MediocreHiram K,Sep 2023
JFK - CLT
Food
6.4
Crew
7.9
Entertainment
6.8
Comfort
7.2
Overall
7.1
Boarding
7.5
Reviews
1 / 20
2.0
MediocreHiram K,Sep 2023
JFK - CLT
Related info for your journey
Find useful and relevant information for your journey from LaGuardia to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsSumter
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Other flights to Florence
Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 17, 2026.
LaGuardia and Florence flights
Browse other LaGuardia and Florence flight options. Last updated on August 17, 2026.
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Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from LaGuardia to Florence
Discover the top airline that operate flights from LaGuardia to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$343 | Average$466 | FlexibilityNo cancel fee | On-time71% |