$504+ Cheap flights from Colorado to Florence, SC (FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — FLO
Oct 3 — Oct 101
Round-trip
1 adult, Economy
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Find cheap flights from Colorado to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Colorado to Florence
Cheapest
Best
Last-minute
Cheapest flights from Colorado to FlorenceExplore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2026.
Explore the most affordable flight options available from Colorado to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:00 am -
2 stops13h 57m
Mon 10/122:34 pm -
1 stop7h 48m
Deal found 9/2![American Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:16 am -
2 stops13h 42m
Mon 9/281:43 pm -
1 stop7h 26m
Deal found 8/31![American Airlines logo]()
$541
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:21 pm -
1 stop7h 33m
Sat 11/285:09 am -
1 stop6h 18m
Deal found 9/2![American Airlines logo]()
$543
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:00 am -
2 stops13h 12m
Wed 10/142:34 pm -
2 stops12h 02m
Deal found 9/2![American Airlines logo]()
$583
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/274:36 pm -
1 stop5h 21m
Sun 1/32:35 pm -
1 stop6h 02m
Deal found 8/29![American Airlines logo]()
$647
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:58 am -
2 stops9h 56m
Sat 11/282:35 pm -
2 stops11h 51m
Deal found 9/2![American Airlines logo]()
$690
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:19 pm -
1 stop7h 38m
Sun 10/185:09 am -
1 stop6h 07m
Deal found 9/2![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:56 pm -
2 stops8h 58m
Sun 11/292:35 pm -
2 stops11h 21m
Deal found 8/31![American Airlines logo]()
$1,184
Best flights from Colorado to FlorenceDiscover carefully curated flight deals from Colorado to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 3, 2026.
Discover carefully curated flight deals from Colorado to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 3, 2026.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:16 am -
2 stops13h 42m
Mon 9/281:43 pm -
1 stop7h 26m
Deal found 8/31![American Airlines logo]()
$541
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:21 pm -
1 stop7h 33m
Sat 11/285:09 am -
1 stop6h 18m
Deal found 9/3![American Airlines logo]()
$543
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:07 pm -
1 stop5h 50m
Mon 10/122:34 pm -
1 stop7h 48m
Deal found 9/2![American Airlines logo]()
$596
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2511:58 am -
2 stops9h 56m
Sat 11/282:35 pm -
2 stops11h 51m
Deal found 9/2![American Airlines logo]()
$690
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:19 pm -
1 stop7h 38m
Sun 10/185:09 am -
1 stop6h 07m
Deal found 8/30![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:56 pm -
2 stops8h 58m
Sun 11/292:35 pm -
2 stops11h 21m
Deal found 8/31![American Airlines logo]()
$1,184
Last-minute flights from Colorado to FlorenceDiscover last-minute flight deals from Colorado to Florence. Data last updated September 3, 2026 and is based on user searches.
Discover last-minute flight deals from Colorado to Florence. Data last updated September 3, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:16 am -
2 stops13h 42m
Mon 9/281:43 pm -
1 stop7h 26m
Deal found 8/31![American Airlines logo]()
$541
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:00 am -
2 stops13h 57m
Mon 10/122:34 pm -
1 stop7h 48m
Deal found 9/2![American Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:19 pm -
1 stop7h 38m
Sun 10/185:09 am -
1 stop6h 07m
Deal found 9/2![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:00 am -
2 stops13h 12m
Wed 10/142:34 pm -
2 stops12h 02m
Deal found 9/2![American Airlines logo]()
$583
Find flight deals from Colorado to Florence
Keep the following information in mind while searching for Colorado to Florence flight deals. Data was last updated September 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $504 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Colorado to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 3, 2026.
Use the filters below to find and compare flights from Colorado to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverFlorence
DEN Denver Intl - FLO Florence
DENFLO
Denver Intl
Mon 9/21
7:16 am-10:58 pm
2 stops13h 42m
Florence
Mon 9/28
1:43 pm-7:09 pm
1 stop7h 26m
$541
DenverFlorence
DEN Denver Intl - FLO Florence
DENFLO
Denver Intl
Wed 11/25
2:21 pm-11:54 pm
1 stop7h 33m
Florence
Sat 11/28
5:09 am-9:27 am
1 stop6h 18m
$543
Quickest round-trip
DenverFlorence
DEN Denver Intl - FLO Florence
DENFLO
Denver Intl
Thu 10/8
4:07 pm-11:57 pm
1 stop5h 50m
Florence
Mon 10/12
2:34 pm-8:22 pm
1 stop7h 48m
$596
Grand JunctionFlorence
GJT Grand Junction Regnl - FLO Florence
GJTFLO
Grand Junction Regnl
Wed 11/25
11:58 am-11:54 pm
2 stops9h 56m
Florence
Sat 11/28
2:35 pm-12:26 am
2 stops11h 51m
$690
DenverFlorence
DEN Denver Intl - FLO Florence
DENFLO
Denver Intl
Fri 10/9
2:19 pm-11:57 pm
1 stop7h 38m
Florence
Sun 10/18
5:09 am-9:16 am
1 stop6h 07m
$733
Colorado SpringsFlorence
COS Colorado Springs - FLO Florence
COSFLO
Colorado Springs
Tue 11/24
12:56 pm-11:54 pm
2 stops8h 58m
Florence
Sun 11/29
2:35 pm-11:56 pm
2 stops11h 21m
$1,184
Sorted by cheapest first
Best time to book a flight from Colorado to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Colorado with our price prediction graph.
DEN-FLO
GJT-FLO
COS-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Colorado to Florence
USCO-FLO
DEN-FLO
GJT-FLO
COS-FLO
No data available for this route at this time. Please check back soon.
Related info for your journey
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