$110+ Cheap flights from St. Louis to Des Moines (STL - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Des Moines
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Cheapest flights from St. Louis to Des MoinesExplore the most affordable flight options available from St. Louis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from St. Louis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:01 am -
1 stop6h 25m
Thu 9/247:58 pm -
1 stop4h 29m
Deal found 8/5![American Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:50 pm -
1 stop5h 09m
Mon 9/76:55 am -
1 stop3h 28m
Deal found 8/4![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:05 pm -
2 stops6h 50m
Thu 8/275:40 am -
1 stop4h 50m
Deal found 8/4![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:50 pm -
2 stops6h 10m
Wed 8/262:40 pm -
2 stops7h 30m
Deal found 8/4![Southwest logo]()
$255
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:15 pm -
1 stop3h 55m
Fri 8/282:25 pm -
1 stop5h 20m
Deal found 8/2![Southwest logo]()
$271
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:15 am -
1 stop4h 02m
Sun 9/275:59 pm -
1 stop5h 17m
Deal found 8/4![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:40 pm -
2 stops8h 15m
Mon 9/75:40 am -
1 stop3h 35m
Deal found 8/4![Southwest logo]()
$307
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:30 am -
1 stop4h 46m
Tue 8/258:00 am -
1 stop6h 28m
Deal found 8/4![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:45 pm -
2 stops6h 30m
Thu 9/245:40 am -
2 stops9h 40m
Deal found 8/5![Southwest logo]()
$312
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:00 am -
1 stop6h 15m
Mon 10/126:55 pm -
1 stop4h 04m
Deal found 8/3![United Airlines logo]()
$315
Best flights from St. Louis to Des MoinesDiscover carefully curated flight deals from St. Louis to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from St. Louis to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:01 am -
1 stop6h 25m
Thu 9/247:58 pm -
1 stop4h 29m
Deal found 8/5![American Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:50 pm -
1 stop5h 09m
Mon 9/76:55 am -
1 stop3h 28m
Deal found 8/4![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:05 am -
1 stop5h 20m
Mon 8/315:40 am -
2 stops9h 40m
Deal found 8/2![Southwest logo]()
$250
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:00 am -
1 stop6h 15m
Mon 10/126:55 pm -
1 stop4h 04m
Deal found 8/4![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:45 pm -
1 stop6h 10m
Tue 9/82:40 pm -
2 stops7h 35m
Deal found 8/4![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am -
1 stop6h 55m
Wed 8/266:10 am -
2 stops8h 15m
Deal found 8/4![Southwest logo]()
$250
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:15 am -
1 stop4h 02m
Sun 9/275:59 pm -
1 stop5h 17m
Deal found 8/5![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 pm -
1 stop4h 00m
Thu 9/105:40 am -
2 stops9h 40m
Deal found 8/7![Southwest logo]()
$302
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:05 pm -
2 stops6h 50m
Mon 9/75:40 am -
1 stop3h 35m
Deal found 8/2![Southwest logo]()
$307
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:45 pm -
2 stops6h 30m
Thu 9/245:40 am -
2 stops9h 40m
Deal found 8/5![Southwest logo]()
$312
Last-minute flights from St. Louis to Des MoinesDiscover last-minute flight deals from St. Louis to Des Moines. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Des Moines. Data last updated August 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:30 am -
1 stop4h 46m
Tue 8/258:00 am -
1 stop6h 28m
Deal found 8/4![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:05 pm -
1 stop4h 55m
Tue 8/256:10 am -
2 stops10h 15m
Deal found 8/4![Southwest logo]()
$315
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:15 pm -
1 stop3h 55m
Fri 8/282:25 pm -
1 stop5h 20m
Deal found 8/2![Southwest logo]()
$271
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:05 pm -
2 stops6h 50m
Thu 8/275:40 am -
1 stop4h 50m
Deal found 8/4![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:50 pm -
2 stops6h 10m
Wed 8/262:40 pm -
2 stops7h 30m
Deal found 8/4![Southwest logo]()
$255
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:50 pm -
1 stop5h 09m
Mon 9/76:55 am -
1 stop3h 28m
Deal found 8/4![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:40 pm -
2 stops8h 15m
Mon 9/75:40 am -
1 stop3h 35m
Deal found 8/4![Southwest logo]()
$307
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:01 am -
1 stop6h 25m
Thu 9/247:58 pm -
1 stop4h 29m
Deal found 8/5![American Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:45 pm -
2 stops6h 30m
Thu 9/245:40 am -
2 stops9h 40m
Deal found 8/5![Southwest logo]()
$312
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:15 am -
1 stop4h 02m
Sun 9/275:59 pm -
1 stop5h 17m
Deal found 8/4![Delta logo]()
$302
One-way flights from St. Louis to Des MoinesSearch for one-way flight options from St. Louis to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from St. Louis to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:01 am -
1 stop6h 25m
Deal found 8/3![American Airlines logo]()
$110
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:15 pm -
2 stops7h 00m
Deal found 8/3![Southwest logo]()
$115
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am -
1 stop4h 00m
Deal found 8/2![American Airlines logo]()
$123
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:05 pm -
2 stops6h 50m
Deal found 8/3![Southwest logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:10 pm -
2 stops18h 28m
Deal found 8/2![Multiple Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:00 pm -
2 stops9h 14m
Deal found 8/3![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:45 pm -
3 stops42h 23m
Deal found 8/2![Multiple Airlines logo]()
$187
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:15 pm -
1 stop3h 55m
Deal found 8/3![Southwest logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:32 pm -
3 stops21h 27m
Deal found 8/6![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:20 am -
3 stops26h 17m
Deal found 8/4![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:39 pm -
3 stops27h 29m
Deal found 8/3![Multiple Airlines logo]()
$271
Find flight deals from St. Louis to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $219 (American Airlines) |
One-way from | $110 (American Airlines) |
Popular in | February |
Cheapest in | October |
Average price | $262 |
Good one-way deal | $194 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from St. Louis to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Mon 9/21
11:01 am-5:26 pm
1 stop6h 25m
Des Moines
Thu 9/24
7:58 pm-12:27 am
1 stop4h 29m
$219
Quickest round-trip
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Tue 9/1
3:50 pm-8:59 pm
1 stop5h 09m
Des Moines
Mon 9/7
6:55 am-10:23 am
1 stop3h 28m
$245
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Thu 8/27
6:05 am-11:25 am
1 stop5h 20m
Des Moines
Mon 8/31
5:40 am-3:20 pm
2 stops9h 40m
$250
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Tue 9/1
3:45 pm-9:55 pm
1 stop6h 10m
Des Moines
Tue 9/8
2:40 pm-10:15 pm
2 stops7h 35m
$250
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Tue 8/25
7:00 am-1:55 pm
1 stop6h 55m
Des Moines
Wed 8/26
6:10 am-2:25 pm
2 stops8h 15m
$250
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Thu 9/24
6:15 am-10:17 am
1 stop4h 02m
Des Moines
Sun 9/27
5:59 pm-11:16 pm
1 stop5h 17m
$302
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Thu 9/3
6:15 pm-10:15 pm
1 stop4h 00m
Des Moines
Thu 9/10
5:40 am-3:20 pm
2 stops9h 40m
$302
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Tue 9/1
3:05 pm-9:55 pm
2 stops6h 50m
Des Moines
Mon 9/7
5:40 am-9:15 am
1 stop3h 35m
$307
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Mon 9/21
3:45 pm-10:15 pm
2 stops6h 30m
Des Moines
Thu 9/24
5:40 am-3:20 pm
2 stops9h 40m
$312
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Thu 10/8
8:00 am-2:15 pm
1 stop6h 15m
Des Moines
Mon 10/12
6:55 pm-10:59 pm
1 stop4h 04m
$315
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Des Moines in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from St. Louis with our price prediction graph.
STL-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 7, 2026.
Read reviews from past customers who have flown Southwest and United Airlines from St. Louis to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 7, 2026.
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Find flights from St. Louis to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Des Moines flights
Browse other St. Louis and Des Moines flight options. Last updated on August 7, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on August 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from St. Louis to Des Moines
Discover the top 2 airlines that operate flights from St. Louis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$371 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$218 | Average$519 | FlexibilityNo cancel fee | On-time69% |