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Des Moines

$49+ Cheap flights from St. Louis to Des Moines (STL - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Find flight deals from St. Louis to Des Moines

Cheapest flights from St. Louis to Des Moines
Explore the most affordable flight options available from St. Louis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:50 amSTL - DSM
Nonstop1h 10mSouthwest
Mon 11/105:45 amDSM - STL
Nonstop1h 20mSouthwest
Deal found 10/16$97
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:45 pmSTL - DSM
1 stop18h 02mFrontier
Mon 11/102:32 pmDSM - STL
1 stop18h 35mFrontier
Deal found 10/16$132
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/118:25 pmSTL - DSM
Nonstop1h 10mSouthwest
Thu 11/135:45 amDSM - STL
Nonstop1h 20mSouthwest
Deal found 10/15$134
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:42 amSTL - DSM
1 stop5h 09mAmerican Airlines
Tue 11/1811:30 amDSM - STL
1 stop4h 57mAmerican Airlines
Deal found 10/14$159
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:00 amSTL - DSM
1 stop4h 19mUnited Airlines
Tue 11/118:02 amDSM - STL
1 stop6h 22mUnited Airlines
Deal found 10/15$170
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:34 pmSTL - DSM
1 stop3h 41mDelta
Thu 11/136:32 pmDSM - STL
1 stop5h 12mDelta
Deal found 10/14$181
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:40 amSTL - DSM
2 stops10h 32mDelta
Tue 11/186:50 amDSM - STL
1 stop5h 09mDelta
Deal found 10/14$186
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:40 pmSTL - DSM
1 stop17h 07mFrontier
Sun 11/22:32 pmDSM - STL
1 stop18h 35mFrontier
Deal found 10/14$192
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/611:07 amSTL - DSM
2 stops27h 48mMultiple Airlines
Mon 11/102:32 pmDSM - STL
1 stop18h 35mMultiple Airlines
Deal found 10/16$198
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:50 amSTL - DSM
Nonstop1h 10mSouthwest
Mon 12/226:35 amDSM - STL
1 stop5h 45mSouthwest
Deal found 10/16$213
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/81:45 pmSTL - DSM
Nonstop1h 10mSouthwest
Tue 11/114:15 pmDSM - STL
Nonstop1h 05mSouthwest
Deal found 10/15$224

Cheap flight deals from St. Louis to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$97
(Southwest)

One-way from

$49
(Southwest)

Popular in

March

Cheapest in

June

Average price

$218

Good round-trip deal

$171 or less

Good one-way deal

$164 or less
Provider with most accurate pricing for Lambert-St Louis-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Des Moines flights.
Search Deals
From Lambert-St Louis to Des Moines
Search Deals
One-way flight from Lambert-St Louis to Des Moines
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($86 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Lambert-St Louis to Des Moines.
Search Deals
Price to beat on a one-way flight from Lambert-St Louis to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from St. Louis to Des Moines that are best for you.

Fly from

St. Louis

Fly to

Des Moines

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 11/6

7:45 pm-1:47 pm

1 stop18h 02m

Des Moines

Mon 11/10

2:32 pm-9:07 am

1 stop18h 35m

$132

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 12/17

10:15 am-11:25 am

Nonstop1h 10m

Des Moines

Thu 12/18

5:45 am-7:05 am

Nonstop1h 20m

$134

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 11/11

8:25 pm-9:35 pm

Nonstop1h 10m

Des Moines

Thu 11/13

5:45 am-7:05 am

Nonstop1h 20m

$134

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 1/8

8:00 pm-9:10 pm

Nonstop1h 10m

Des Moines

Thu 1/15

11:30 am-8:15 pm

1 stop8h 45m

$144

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 11/8

10:00 am-2:19 pm

1 stop4h 19m

Des Moines

Tue 11/11

8:02 am-2:24 pm

1 stop6h 22m

$170

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Mon 11/10

5:34 pm-9:15 pm

1 stop3h 41m

Des Moines

Thu 11/13

6:32 pm-11:44 pm

1 stop5h 12m

$181

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 12/17

6:00 am-1:31 pm

1 stop7h 31m

Des Moines

Thu 12/18

5:34 am-1:02 pm

1 stop7h 28m

$181

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 12/18

6:00 am-10:38 am

1 stop4h 38m

Des Moines

Mon 12/22

5:55 pm-10:16 pm

1 stop4h 21m

$181

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 1/8

5:30 pm-9:27 pm

1 stop3h 57m

Des Moines

Thu 1/15

10:55 am-4:50 pm

1 stop5h 55m

$181

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 11/11

6:40 am-5:12 pm

2 stops10h 32m

Des Moines

Tue 11/18

6:50 am-11:59 am

1 stop5h 09m

$186

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 21 results
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Compare providers for flights from St. Louis to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Des Moines in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Des Moines

What is the cheapest time of day to fly from STL to DSM?

Find hourly flight availability from St. Louis to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

When flying from St. Louis to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 64% versus a flight in the morning.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 16, 2025.
Read reviews from past customers who have flown Southwest from St. Louis to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from St. Louis to Des Moines?

    To fly from St. Louis to Des Moines, you need to book a flight from Lambert-St Louis (STL) to Des Moines (DSM). Nonstop flights to Des Moines from Lambert-St Louis take 1h 10m on average. When it comes time to book airfare, you have a few options: there is 1 outbound flight from Lambert-St Louis to Des Moines offered by 1 airline.

  • How popular is this St. Louis to Des Moines flight route?

    The Lambert-St Louis to Des Moines flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from St. Louis to Des Moines?

    Departing from St. Louis to Des Moines will take you 1h 10m. The distance between St. Louis and Des Moines is about 259 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from St. Louis to Des Moines round-trip?

    Flying on Southwest is currently your cheapest option to Des Moines, with prices starting at $77. Southwest is currently priced 74% below the average price you’ll pay for this route.

  • What are the cheapest flights from St. Louis to Des Moines?

    On average you can expect to pay $333 for a flight from St. Louis to Des Moines. The cheapest flight overall is $38 while the most popular route, (Lambert-St Louis - Des Moines) is currently priced at $134.

  • Can I find deals for flights from St. Louis to Des Moines that include hotel bookings?

    Yes. In addition to deals on St. Louis to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Des Moines.

  • Can I find deals for business class flights from St. Louis to Des Moines?

    Yes. Cheapflights offers flight deals from St. Louis to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top airline flying from St. Louis to Des Moines

Discover the top airline that operate flights from St. Louis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$77Average$309FlexibilityNo cancel feeOn-time63%

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