HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$69+ Cheap flights from St. Louis to Des Moines (STL - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from St. Louis to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Des Moines

Cheapest flights from St. Louis to Des Moines
Explore the most affordable flight options available from St. Louis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
STL
-
DSM
1 stop5h 05m
Delta
Thu 4/307:00 am
DSM
-
STL
1 stop4h 32m
Delta
Deal found 2/4$157
This Southwest deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:30 pm
STL
-
DSM
2 stops7h 40m
Southwest
Thu 4/304:20 pm
DSM
-
STL
1 stop6h 25m
Southwest
Deal found 2/4$194
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:10 am
STL
-
DSM
1 stop4h 07m
Delta
Mon 3/25:15 pm
DSM
-
STL
1 stop6h 21m
Delta
Deal found 2/4$205
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:40 am
STL
-
DSM
1 stop6h 00m
Southwest
Wed 4/11:55 pm
DSM
-
STL
1 stop7h 40m
Southwest
Deal found 2/2$232
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:45 am
STL
-
DSM
1 stop6h 39m
United Airlines
Sun 5/103:20 pm
DSM
-
STL
1 stop5h 48m
United Airlines
Deal found 2/4$254
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:45 pm
STL
-
DSM
1 stop6h 54m
Delta
Sun 4/266:10 am
DSM
-
STL
1 stop6h 55m
Delta
Deal found 2/1$259
This Southwest deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:40 am
STL
-
DSM
1 stop6h 05m
Southwest
Sun 5/104:20 pm
DSM
-
STL
2 stops7h 25m
Southwest
Deal found 2/4$289
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:45 pm
STL
-
DSM
1 stop5h 22m
United Airlines
Sat 2/283:24 pm
DSM
-
STL
1 stop5h 41m
United Airlines
Deal found 2/1$324

Find flight deals from St. Louis to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$157
(Delta)

One-way from

$69
(Southwest)

Popular in

January

Cheapest in

October

Average price

$519

Good round-trip deal

$467 or less
Provider with most accurate pricing for Lambert-St Louis-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Des Moines flights.
Search Deals
From Lambert-St Louis to Des Moines
Search Deals
One-way flight from Lambert-St Louis to Des Moines
Search Deals
Highest demand for flights based on searches. 35% potential increase in price ($213 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Lambert-St Louis to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from St. Louis to Des Moines that are best for you.

Fly from

St. Louis

Fly to

Des Moines

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 4/28

6:00 am-11:05 am

1 stop5h 05m

Des Moines

Thu 4/30

7:00 am-11:32 am

1 stop4h 32m

$157

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 4/28

2:30 pm-10:10 pm

2 stops7h 40m

Des Moines

Thu 4/30

4:20 pm-10:45 pm

1 stop6h 25m

$194

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 2/28

6:10 am-10:17 am

1 stop4h 07m

Des Moines

Mon 3/2

10:57 am-8:43 pm

2 stops9h 46m

$210

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 3/24

5:40 am-11:40 am

1 stop6h 00m

Des Moines

Wed 4/1

1:55 pm-9:35 pm

1 stop7h 40m

$232

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 4/23

1:45 pm-8:39 pm

1 stop6h 54m

Des Moines

Sun 4/26

6:10 am-1:05 pm

1 stop6h 55m

$259

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 2/25

2:45 pm-8:07 pm

1 stop5h 22m

Des Moines

Sat 2/28

3:24 pm-9:05 pm

1 stop5h 41m

$324

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sun 3/29

7:45 am-12:29 pm

1 stop4h 44m

Des Moines

Mon 3/30

3:21 pm-9:08 pm

1 stop5h 47m

$327

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sun 3/29

5:20 am-11:30 am

1 stop6h 10m

Des Moines

Mon 3/30

4:20 pm-12:05 am

2 stops7h 45m

$332

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 4/1

3:10 pm-10:05 pm

2 stops6h 55m

$74

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 5/5

7:25 am-1:55 pm

1 stop6h 30m

$79

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 15 results
1
2

Compare providers for flights from St. Louis to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Des Moines in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Des Moines

What is the cheapest time of day to fly from STL to DSM?

Find hourly flight availability from St. Louis to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 4, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from St. Louis to Des Moines as you normally would.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 4, 2026.
Read reviews from past customers who have flown Southwest from St. Louis to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,274 reviews

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,274 reviews
Southwest
8.0
Very good
4,274 reviews

Comfort

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from St. Louis to Des Moines?

    To fly from St. Louis to Des Moines, you need to book a flight from Lambert-St Louis (STL) to Des Moines (DSM). Nonstop flights to Des Moines from Lambert-St Louis take 1h 10m on average. When it comes time to book airfare, you have a few options: there is 1 outbound flight from Lambert-St Louis to Des Moines offered by 1 airline.

  • How popular is this St. Louis to Des Moines flight route?

    The Lambert-St Louis to Des Moines flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from St. Louis to Des Moines?

    Departing from St. Louis to Des Moines will take you 5h 05m. The distance between St. Louis and Des Moines is about 259 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from St. Louis to Des Moines round-trip?

    Flying on Southwest is currently your cheapest option to Des Moines, with prices starting at $77. Southwest is currently priced 80% below the average price you’ll pay for this route.

  • What are the cheapest flights from St. Louis to Des Moines?

    On average you can expect to pay $649 for a flight from St. Louis to Des Moines. The cheapest flight overall is $316 while the most popular route, (Lambert-St Louis - Des Moines) is currently priced at $232.

  • Can I find deals for flights from St. Louis to Des Moines that include hotel bookings?

    Yes. In addition to deals on St. Louis to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Des Moines.

  • Can I find deals for business class flights from St. Louis to Des Moines?

    Yes. Cheapflights offers flight deals from St. Louis to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from St. Louis to Des Moines

Discover the top airline that operate flights from St. Louis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$77Average$309FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.