$114+ Cheap flights from Illinois to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — DSM
Nov 21 — Nov 281
Round-trip
1 adult, Economy
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Find cheap flights from Illinois to Des Moines with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Illinois to Des MoinesExplore the most affordable flight options available from Illinois to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
Explore the most affordable flight options available from Illinois to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2026.
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:05 am -
Nonstop1h 25m
Sun 11/155:25 am -
Nonstop1h 30m
Deal found 10/21![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:40 pm -
Nonstop1h 25m
Wed 11/187:00 am -
2 stops10h 05m
Deal found 10/21![Southwest logo]()
$242
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:53 pm -
Nonstop1h 33m
Wed 11/189:25 am -
Nonstop1h 45m
Deal found 10/21![American Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:54 am -
Nonstop1h 34m
Tue 11/107:26 pm -
Nonstop1h 47m
Deal found 10/21![American Airlines logo]()
$252
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:40 pm -
Nonstop1h 25m
Mon 12/73:25 pm -
Nonstop1h 30m
Deal found 10/18![Southwest logo]()
$252
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:00 pm -
Nonstop1h 40m
Sat 12/129:23 am -
Nonstop1h 47m
Deal found 10/21![American Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:05 am -
Nonstop1h 25m
Mon 11/307:15 pm -
Nonstop1h 20m
Deal found 10/21![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:23 am -
1 stop3h 56m
Wed 11/186:45 am -
1 stop5h 03m
Deal found 10/21![Delta logo]()
$271
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:29 pm -
1 stop3h 44m
Wed 11/186:45 am -
1 stop5h 05m
Deal found 10/21![Delta logo]()
$271
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:38 pm -
1 stop6h 39m
Mon 11/2311:00 am -
1 stop3h 55m
Deal found 10/19![Delta logo]()
$272
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:34 am -
1 stop3h 34m
Mon 11/2311:00 am -
1 stop5h 39m
Deal found 10/19![Delta logo]()
$272
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:05 am -
Nonstop1h 25m
Thu 12/36:00 am -
Nonstop1h 25m
Deal found 10/21![Southwest logo]()
$276
Best flights from Illinois to Des MoinesDiscover carefully curated flight deals from Illinois to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
Discover carefully curated flight deals from Illinois to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 22, 2026.
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:55 am -
1 stop7h 15m
Sun 11/155:25 am -
Nonstop1h 30m
Deal found 10/21![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:30 am -
1 stop4h 02m
Sat 11/73:15 pm -
1 stop6h 07m
Deal found 10/19![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:47 pm -
1 stop5h 26m
Sat 11/282:48 pm -
1 stop4h 51m
Deal found 10/21![Delta logo]()
$398
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:15 am -
2 stops10h 35m
Thu 12/103:25 pm -
Nonstop1h 30m
Deal found 10/19![Southwest logo]()
$273
This KAYAK deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:53 pm -
Nonstop1h 33m
Tue 11/106:00 am -
1 stop6h 24m
Deal found 10/19![American Airlines logo]()
$588
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:05 am -
1 stop8h 10m
Sun 1/37:15 pm -
Nonstop1h 20m
Deal found 10/21![Southwest logo]()
$353
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/197:45 pm -
Nonstop1h 38m
Sat 1/29:32 am -
Nonstop1h 43m
Deal found 10/19![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:29 pm -
1 stop3h 44m
Fri 11/276:45 am -
1 stop3h 40m
Deal found 10/19![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:30 am -
1 stop8h 30m
Sat 11/284:15 pm -
Nonstop1h 25m
Deal found 10/21![Southwest logo]()
$371
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/73:30 pm -
1 stop5h 30m
Sun 11/810:57 am -
1 stop5h 43m
Deal found 10/17![Delta logo]()
$447
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:05 pm -
Nonstop1h 30m
Fri 11/276:40 am -
1 stop5h 20m
Deal found 10/19![Southwest logo]()
$371
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2911:10 pm -
Nonstop1h 30m
Mon 11/307:15 pm -
Nonstop1h 20m
Deal found 10/18![Southwest logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:00 am -
1 stop9h 07m
Sun 11/156:45 pm -
Nonstop1h 40m
Deal found 10/20![United Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:23 am -
1 stop3h 56m
Sun 11/1510:24 am -
1 stop5h 54m
Deal found 10/20![Delta logo]()
$479
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2310:00 pm -
1 stop18h 16m
Sat 12/269:32 am -
Nonstop1h 43m
Deal found 10/20![United Airlines logo]()
$528
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:47 pm -
1 stop14h 44m
Sat 11/288:00 am -
Nonstop1h 40m
Deal found 10/21![United Airlines logo]()
$528
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:23 am -
1 stop3h 56m
Mon 11/302:48 pm -
1 stop4h 51m
Deal found 10/20![Delta logo]()
$539
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:00 am -
1 stop5h 32m
Thu 11/126:45 pm -
1 stop4h 14m
Deal found 10/20![United Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:50 am -
1 stop13h 35m
Sat 12/266:42 pm -
Nonstop1h 43m
Deal found 10/20![United Airlines logo]()
$566
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:00 am -
2 stops11h 07m
Thu 11/59:50 am -
1 stop4h 05m
Deal found 10/17![United Airlines logo]()
$1,011
Last-minute flights from Illinois to Des MoinesDiscover last-minute flight deals from Illinois to Des Moines. Data last updated October 22, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to Des Moines. Data last updated October 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:54 am -
Nonstop1h 34m
Tue 11/107:26 pm -
Nonstop1h 47m
Deal found 10/21![American Airlines logo]()
$252
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:53 pm -
Nonstop1h 33m
Wed 11/189:25 am -
Nonstop1h 45m
Deal found 10/21![American Airlines logo]()
$251
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:23 am -
1 stop3h 56m
Wed 11/186:45 am -
1 stop5h 03m
Deal found 10/21![Delta logo]()
$271
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:29 pm -
1 stop3h 44m
Wed 11/186:45 am -
1 stop5h 05m
Deal found 10/21![Delta logo]()
$271
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:05 am -
Nonstop1h 25m
Sun 11/155:25 am -
Nonstop1h 30m
Deal found 10/21![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:40 pm -
Nonstop1h 25m
Wed 11/187:00 am -
2 stops10h 05m
Deal found 10/21![Southwest logo]()
$242
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:38 pm -
1 stop6h 39m
Mon 11/2311:00 am -
1 stop3h 55m
Deal found 10/19![Delta logo]()
$272
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:34 am -
1 stop3h 34m
Mon 11/2311:00 am -
1 stop5h 39m
Deal found 10/19![Delta logo]()
$272
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:05 am -
Nonstop1h 25m
Mon 11/307:15 pm -
Nonstop1h 20m
Deal found 10/21![Southwest logo]()
$258
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:45 pm -
Nonstop1h 34m
Fri 11/277:24 pm -
Nonstop1h 50m
Deal found 10/20![American Airlines logo]()
$288
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:05 pm -
Nonstop1h 30m
Fri 11/275:25 am -
Nonstop1h 30m
Deal found 10/19![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:05 am -
Nonstop1h 25m
Thu 12/36:00 am -
Nonstop1h 25m
Deal found 10/21![Southwest logo]()
$276
One-way flights from Illinois to Des MoinesSearch for one-way flight options from Illinois to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
Search for one-way flight options from Illinois to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 22, 2026.
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/188:50 pm -
Nonstop1h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$114
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1810:43 pm -
Nonstop1h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$126
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:35 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$126
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:45 pm -
2 stops9h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$129
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:26 am -
Nonstop1h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$130
This CheapOair deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:30 am -
1 stop13h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Frontier logo]()
$134
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:05 am -
Nonstop1h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$135
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:42 pm -
1 stop3h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$136
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:29 pm -
1 stop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:45 am -
1 stop11h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:16 am -
2 stops33h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$140
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:59 am -
1 stop4h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$144
Find flight deals from Illinois to Des Moines
Keep the following information in mind while searching for Illinois to Des Moines flight deals. Data was last updated October 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Southwest) |
One-way from | $114 (Southwest) |
Popular in | August |
Cheapest in | February |
Average price | $408 |
Good round-trip deal | $259 or less |
Good one-way deal | $180 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
Use the filters below to find and compare flights from Illinois to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Mon 1/18
8:50 pm-10:15 pm
Nonstop1h 25m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$114
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Wed 1/13
10:05 am-11:30 am
Nonstop1h 25m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$114
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Wed 1/20
10:05 am-11:30 am
Nonstop1h 25m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$114
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Wed 1/13
8:55 am-10:41 am
Nonstop1h 46m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$126
Quickest round-trip
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Wed 11/11
10:05 am-11:25 am
Nonstop1h 20m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$135
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Wed 1/20
6:00 am-10:20 am
1 stop4h 20m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Mon 11/23
5:29 pm-9:13 pm
1 stop3h 44m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Wed 11/11
12:30 pm-7:15 pm
1 stop6h 45m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$144
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Mon 11/30
10:05 pm-11:35 pm
Nonstop1h 30m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$144
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Sun 11/29
8:25 pm-9:55 pm
Nonstop1h 30m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$200
Showing 1-10 of 40 resultsSorted by cheapest first
Best time to book a flight from Illinois to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Illinois with our price prediction graph.
MDW-DSM
ORD-DSM
MLI-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to Des Moines
USIL-DSM
MDW-DSM
ORD-DSM
MLI-DSM
What is the cheapest month to book a flight from Illinois to Des Moines?
Currently, February is the cheapest month in which you can book a flight from Illinois to Des Moines (average of $301). Flying from Illinois to Des Moines in August is currently the most expensive (average of $538). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to DSM?
Find hourly flight availability from Illinois to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 22, 2026.
A simple way to save on the total cost of your ticket is to fly from Illinois to Des Moines at noon. If you’re flexible enough to do this you can expect to save up to 52% on your trip compared to booking a flight in the afternoon.
Weekly flight availability from Illinois to Des Moines
Explore weekly flight availability from Illinois to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 22, 2026.
The most flights from USIL to DSM are scheduled on a Wednesday (42 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (9 on average).
How much does it cost to fly round-trip from Illinois to Des Moines?
Airfare is below average for this route at the moment.
Illinois to Des Moines flights typically cost between $254 and $446 in November.The cheapest round-trip price found within the last 5 days was $251 on American Airlines (Nov 11-Nov 18).
What is the cheapest day to fly from Illinois to Des Moines?
Use this chart to determine the cheapest time to fly round-trip from Illinois to Des Moines. Price data was last updated on October 17, 2026.
Travelers seeking maximum savings on their Illinois to Des Moines flight should consider departing on Saturday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Related info for your journey
Find useful and relevant information for your journey from Illinois to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Alternative routes for Illinois to Des Moines
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 22, 2026.
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Illinois and Des Moines flights
Browse other Illinois and Des Moines flight options. Last updated on October 22, 2026.
Popular flight searches
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Illinois to Des Moines flights
Consider these flights traveling from Illinois to Des Moines.
Top 3 airlines flying from Illinois to Des Moines
Discover the top 3 airlines that operate flights from Illinois to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$447 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$209 | Average$463 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$211 | Average$369 | FlexibilityNo cancel fee | On-time71% |