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Des Moines

$49+ Cheap flights from Illinois to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — DSM
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Illinois to Des Moines

Keep the following information in mind while searching for Illinois to Des Moines flight deals. Data was last updated September 17, 2025.

Round-trip from

$97
(Southwest)

One-way from

$49
(Southwest)

Popular in

February

Cheapest in

March

Average price

$259

Good round-trip deal

$189 or less

Good one-way deal

$283 or less
From Illinois to Des Moines
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One-way flight from Illinois to Des Moines
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Highest demand for flights based on searches. 12% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Illinois to Des Moines.
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Price to beat on a one-way flight from Illinois to Des Moines.
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Find flight deals from Illinois to Des Moines

Cheapest flights from Illinois to Des Moines
Explore the most affordable flight options available from Illinois to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/78:20 amSTL - DSM
Nonstop1h 10mSouthwest
Sat 10/113:50 pmDSM - STL
Nonstop1h 10mSouthwest
Deal found 9/16$97
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1010:20 pmSTL - DSM
Nonstop1h 10mSouthwest
Mon 10/135:35 amDSM - STL
Nonstop1h 10mSouthwest
Deal found 9/15$134
This Priceline deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:00 amORD - DSM
1 stop7h 49mFrontier
Sun 11/162:32 pmDSM - ORD
1 stop9h 43mFrontier
Deal found 9/16$148
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:00 amORD - DSM
1 stop7h 47mFrontier
Thu 11/62:32 pmDSM - ORD
1 stop9h 43mFrontier
Deal found 9/15$159
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/78:42 amSTL - DSM
1 stop4h 36mAmerican Airlines
Sat 10/113:48 pmDSM - STL
1 stop5h 05mAmerican Airlines
Deal found 9/15$159
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:52 pmSTL - DSM
1 stop18h 00mFrontier
Thu 10/162:37 pmDSM - STL
1 stop18h 30mFrontier
Deal found 9/16$171
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amSTL - DSM
1 stop4h 26mDelta
Mon 10/205:32 pmDSM - STL
1 stop5h 52mDelta
Deal found 9/16$177
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:00 amSTL - DSM
1 stop5h 32mUnited Airlines
Thu 10/166:30 amDSM - STL
1 stop4h 19mUnited Airlines
Deal found 9/15$179
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1110:30 amSTL - DSM
1 stop6h 00mDelta
Sat 10/1812:30 pmDSM - STL
2 stops9h 34mDelta
Deal found 9/16$182
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:00 amSTL - DSM
1 stop4h 26mDelta
Sat 10/185:15 pmDSM - STL
1 stop4h 49mDelta
Deal found 9/16$184
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:00 amORD - DSM
Nonstop1h 32mAmerican Airlines
Mon 11/179:02 amDSM - ORD
Nonstop1h 47mAmerican Airlines
Deal found 9/16$189
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:35 pmORD - DSM
Nonstop1h 36mAmerican Airlines
Sun 10/126:07 pmDSM - ORD
Nonstop1h 43mAmerican Airlines
Deal found 9/15$190

Cheapflights Fare Finder

 
Customize your flight search to find flights from Illinois to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Illinois to Des Moines that are best for you.

Fly from

Illinois

Fly to

Des Moines

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 10/7

8:20 am-9:30 am

Nonstop1h 10m

Des Moines

Sat 10/11

3:50 pm-5:00 pm

Nonstop1h 10m

$97

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 10/14

1:30 pm-8:55 pm

1 stop7h 25m

Des Moines

Sat 10/18

3:50 pm-5:00 pm

Nonstop1h 10m

$107

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 10/10

10:20 pm-11:30 pm

Nonstop1h 10m

Des Moines

Mon 10/13

5:35 am-6:45 am

Nonstop1h 10m

$134

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 10/31

6:00 am-11:22 am

1 stop5h 22m

Des Moines

Sat 11/1

3:48 pm-8:53 pm

1 stop5h 05m

$159

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 10/7

8:42 am-1:18 pm

1 stop4h 36m

Des Moines

Sat 10/11

3:48 pm-8:53 pm

1 stop5h 05m

$159

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 10/11

6:00 am-10:26 am

1 stop4h 26m

Des Moines

Tue 10/21

5:47 am-12:35 pm

1 stop6h 48m

$177

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 10/16

6:00 am-10:26 am

1 stop4h 26m

Des Moines

Sat 10/18

11:06 am-3:31 pm

1 stop4h 25m

$177

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 10/14

3:30 pm-9:03 pm

1 stop5h 33m

Des Moines

Tue 10/21

11:06 am-2:32 pm

1 stop3h 26m

$177

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 10/14

5:31 pm-9:03 pm

1 stop3h 32m

Des Moines

Mon 10/20

5:32 pm-11:24 pm

1 stop5h 52m

$177

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 10/9

5:00 am-10:32 am

1 stop5h 32m

Des Moines

Thu 10/16

6:30 am-10:49 am

1 stop4h 19m

$179

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from Illinois to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Illinois with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Illinois to Des Moines

What is the cheapest month to book a flight from Illinois to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Illinois to Des Moines (average of $336). Flying from Illinois to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IL to DSM?

Find hourly flight availability from Illinois to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Illinois to Des Moines as you normally would.

Weekly flight availability from Illinois to Des Moines

Explore weekly flight availability from Illinois to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2025.

The most flights from USIL to DSM are scheduled on a Thursday (45 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (20 on average).

Related info for your journey

Find useful and relevant information for your journey from Illinois to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Illinois?

    Most people fly into Des Moines (DSM) if they book a flight to Des Moines from Illinois. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Illinois to Des Moines?

    Airlines like Southwest, American Airlines, and Delta fly from Illinois to Des Moines in about 1h 10m. The time it takes to get you to your destination can typically vary by up to 4h 12m. There are 259 mi between Illinois and Des Moines. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Illinois to Des Moines one-way?

    For one-way options, check prices for Southwest. According to our data, you can fly for as low as $49. Users have also found prices from $87 and $99 on Frontier and Delta, respectively.

  • What are the most popular routes from Illinois to Des Moines?

    While some choose either Lambert-St Louis - Des Moines or Chicago Midway - Des Moines, Chicago O'Hare Intl - Des Moines is the most popular route from Illinois to Des Moines.

  • What are the most reliable airlines from Illinois to Des Moines?

    Consider GoJet (100%), Envoy Air (85%) or United Airlines (74%) when booking your flight. These represent the most reliable airlines when flying from Illinois to Des Moines.

  • What are the cheapest flights from Illinois to Des Moines?

    On average you can expect to pay $276 for a flight from Illinois to Des Moines. The cheapest flight overall is $189 while the most popular route, (Chicago O'Hare Intl - Des Moines) is currently priced at $189.

  • Can I find deals for flights from Illinois to Des Moines that include hotel bookings?

    Yes. In addition to deals on Illinois to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Illinois to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Illinois to Des Moines.

  • Can I find deals for business class flights from Illinois to Des Moines?

    Yes. Cheapflights offers flight deals from Illinois to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Illinois to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Illinois to Des Moines (average of $336). Flying from Illinois to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Illinois to Des Moines

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Top 2 airlines flying from Illinois to Des Moines

Discover the top 2 airlines that operate flights from Illinois to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$189Average$279FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$189Average$279FlexibilityNo cancel feeOn-time69%

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