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Des Moines

$379+ Cheap flights from Gainesville to Des Moines (GNV - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — DSM
nov 1 — nov 81
sáb 11/1
sáb 11/8
1 adult, Economy
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Cheap flight deals from Gainesville to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated outubro 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$379
(American Airlines)

Popular in

June

Cheapest in

February

Average price

$627
Provider with most accurate pricing for Gainesville Regional-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Gainesville Regional-Des Moines flights.
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From Gainesville Regional to Des Moines
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($110 potential increase over avg. RT price).
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Cheapest flight prices on average. 12% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Gainesville to Des Moines

Cheapest flights from Gainesville to Des Moines
Explore the most affordable flight options available from Gainesville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on outubro 2, 2025.

This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/246:30 amGNV - DSM
1 stop7h 51mAmerican Airlines
sex 1/23:28 pmDSM - GNV
1 stop5h 52mAmerican Airlines
Deal found 10/2$379
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 10/306:58 pmGNV - DSM
1 stop5h 10mAmerican Airlines
sex 11/73:39 pmDSM - GNV
1 stop5h 58mAmerican Airlines
Deal found 10/2$434
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 11/137:16 amGNV - DSM
1 stop8h 43mAmerican Airlines
sex 11/212:15 pmDSM - GNV
1 stop7h 11mAmerican Airlines
Deal found 10/2$583

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated outubro 2, 2025.
Use the filters below to find and compare flights from Gainesville to Des Moines that are best for you.

Fly from

Gainesville

Fly to

Des Moines

Route

Depart

Return

Price

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

qua 12/24

6:30 am-1:21 pm

1 stop7h 51m

Des Moines

sex 1/2

3:28 pm-10:20 pm

1 stop5h 52m

$379

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

qui 10/30

6:58 pm-11:08 pm

1 stop5h 10m

Des Moines

sex 11/7

3:39 pm-10:37 pm

1 stop5h 58m

$434

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

ter 3/31

6:00 am-10:23 am

1 stop5h 23m

Des Moines

qua 4/1

11:04 am-4:06 pm

1 stop4h 02m

$527

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

qui 11/13

7:16 am-2:59 pm

1 stop8h 43m

Des Moines

sex 11/21

2:15 pm-10:26 pm

1 stop7h 11m

$583

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/2

Compare providers for flights from Gainesville to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to Des Moines in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Des Moines

What is the cheapest month to book a flight from Gainesville to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Gainesville to Des Moines (average of $336). Flying from Gainesville to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to DSM?

Find hourly flight availability from Gainesville to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated outubro 2, 2025.

It’s optimal to fly from Gainesville to Des Moines at noon. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated outubro 2, 2025.
See what other customers who have flown with Delta and American Airlines from Gainesville to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,962 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,962 reviews
Delta
8.0
Very good
7,962 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,033 reviews
Delta
8.0
Very good
7,962 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to Des Moines?

    Departing from Gainesville to Des Moines will take you 5h 23m. Airlines will cover a distance of 1036 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Gainesville to Des Moines round-trip?

    Cheapflights users have booked flights from Gainesville to Des Moines round-trip from $336. Another airline that can offer you cheap pricing is American Airlines. Delta is 43% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Gainesville to Des Moines that include hotel bookings?

    Yes. In addition to deals on Gainesville to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Des Moines.

  • Can I find deals for business class flights from Gainesville to Des Moines?

    Yes. Cheapflights offers flight deals from Gainesville to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Gainesville to Des Moines (average of $336). Flying from Gainesville to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top 2 airlines flying from Gainesville to Des Moines

Discover the top 2 airlines that operate flights from Gainesville to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated outubro 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$336Average$491FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$363Average$495FlexibilityNo cancel feeOn-time71%

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