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$353+ Cheap flights from Gainesville (GNV) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — DSM
Aug 29 — Sep 51
Sat 8/29
Sat 9/5
1 adult, Economy
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Cheap flight deals from Gainesville to Iowa

Cheapest flights from Gainesville to Iowa
Explore the most affordable flight options available from Gainesville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.

This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:12 am
GNV
-
MLI
1 stop7h 10m
Delta
Sat 9/511:08 am
MLI
-
GNV
1 stop4h 34m
Delta
Deal found 7/25$413
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:19 pm
GNV
-
DSM
1 stop6h 57m
American Airlines
Mon 9/74:13 pm
DSM
-
GNV
1 stop5h 29m
American Airlines
Deal found 7/26$439
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:12 am
GNV
-
DSM
1 stop6h 04m
Delta
Mon 9/76:00 am
DSM
-
GNV
2 stops9h 31m
Delta
Deal found 7/27$447
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:44 am
GNV
-
OMA
1 stop6h 46m
American Airlines
Mon 8/316:14 am
OMA
-
GNV
1 stop7h 06m
American Airlines
Deal found 7/25$455
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
GNV
-
OMA
1 stop4h 42m
Delta
Sat 8/154:00 pm
OMA
-
GNV
1 stop4h 28m
Delta
Deal found 7/27$477
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:18 pm
GNV
-
DSM
1 stop6h 54m
American Airlines
Fri 9/254:14 pm
DSM
-
GNV
1 stop6h 00m
American Airlines
Deal found 7/28$491
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:39 pm
GNV
-
OMA
1 stop5h 59m
American Airlines
Sat 8/1510:19 am
OMA
-
GNV
2 stops12h 40m
American Airlines
Deal found 7/27$506
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:33 am
GNV
-
OMA
1 stop7h 13m
Delta
Thu 8/205:30 am
OMA
-
GNV
1 stop5h 53m
Delta
Deal found 7/26$542
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:19 pm
GNV
-
DSM
1 stop7h 11m
American Airlines
Thu 8/134:13 pm
DSM
-
GNV
1 stop5h 29m
American Airlines
Deal found 7/30$596
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:01 pm
GNV
-
OMA
1 stop5h 58m
Delta
Mon 8/175:30 am
OMA
-
GNV
1 stop5h 53m
Delta
Deal found 7/29$597
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:30 am
GNV
-
OMA
1 stop5h 55m
American Airlines
Thu 8/2011:59 am
OMA
-
GNV
2 stops8h 52m
American Airlines
Deal found 7/26$616
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:15 am
GNV
-
OMA
2 stops8h 09m
American Airlines
Mon 8/1710:07 am
OMA
-
GNV
2 stops12h 52m
American Airlines
Deal found 7/29$645

Find flight deals from Gainesville to Iowa

Keep the following information in mind while searching for Gainesville to Iowa flight deals. Data was last updated July 30, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$413
(Delta)

One-way from

$353
(American Airlines)
Provider with most accurate pricing for Gainesville Regional-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Des Moines flights.
Search Deals
From Gainesville Regional to Iowa
Search Deals
One-way flight from Gainesville Regional to Iowa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Gainesville to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GainesvilleMoline

GNV - MLI

GNVMLI

Gainesville Regional

Sat 8/29

10:12 am-4:22 pm

1 stop7h 10m

Moline Quad-City

Sat 9/5

11:08 am-4:42 pm

1 stop4h 34m

$413

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Sat 9/5

10:12 am-3:16 pm

1 stop6h 04m

Des Moines

Mon 9/7

6:00 am-4:31 pm

2 stops9h 31m

$447
Quickest round-trip

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Tue 8/11

6:00 am-9:42 am

1 stop4h 42m

Omaha Eppley Airfield

Sat 8/15

4:00 pm-9:28 pm

1 stop4h 28m

$477

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Fri 9/18

5:18 pm-11:12 pm

1 stop6h 54m

Des Moines

Fri 9/25

4:14 pm-11:14 pm

1 stop6h 00m

$491

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Tue 8/11

6:39 pm-11:38 pm

1 stop5h 59m

Omaha Eppley Airfield

Sat 8/15

10:19 am-11:59 pm

2 stops12h 40m

$506

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Tue 8/25

10:44 am-8:23 pm

2 stops10h 39m

Omaha Eppley Airfield

Mon 8/31

10:07 am-4:47 pm

1 stop5h 40m

$516

GainesvilleDes Moines

GNV - DSM

GNVDSM

Gainesville Regional

Thu 8/13

2:51 pm-6:41 pm

1 stop4h 50m

Des Moines

Mon 8/17

4:13 pm-10:42 pm

1 stop5h 29m

$596

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Thu 8/13

7:01 pm-11:59 pm

1 stop5h 58m

Omaha Eppley Airfield

Mon 8/17

5:30 am-12:23 pm

1 stop5h 53m

$597

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Thu 8/13

6:39 pm-11:38 pm

1 stop5h 59m

Omaha Eppley Airfield

Mon 8/17

6:31 am-6:08 pm

2 stops10h 37m

$616

GainesvilleOmaha

GNV - OMA

GNVOMA

Gainesville Regional

Tue 12/22

3:27 pm-12:25 am

2 stops9h 58m

Omaha Eppley Airfield

Mon 12/28

7:31 pm-3:47 pm

1 stop19h 16m

$718

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 17 resultsSorted by cheapest first
1
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Best time to book a flight from Gainesville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Iowa

No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Gainesville to Iowa?

    Located just 4.2 mi from the city center, Gainesville Regional (GNV) is the airport most travelers will use when flying to Iowa from Gainesville.

  • How long is the flight from Gainesville to Iowa?

    Delta and American Airlines can get you from Gainesville to Iowa in just under 6h 54m. Your travel time can differ by up to 16m. The distance between Gainesville and Iowa is about 1036 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Gainesville to Iowa?

    When deciding which route to take from Gainesville to Iowa consider Gainesville Regional - Des Moines, Gainesville Regional - Omaha Eppley Airfield or Gainesville Regional - Moline Quad-City as they are the most popular.

  • Can I find deals for flights from Gainesville to Iowa that include hotel bookings?

    Yes. In addition to deals on Gainesville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Iowa.

  • Can I find deals for business class flights from Gainesville to Iowa?

    Yes. Cheapflights offers flight deals from Gainesville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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