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Des Moines

$149+ Cheap flights from Durham, NC to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — DSM
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Durham to Des Moines are usually found in January or April, booked 48 days in advance, depart on a Friday or Wednesday and return on a Wednesday

Cheap flight deals from Durham to Des Moines

Keep the following information in mind while searching for Durham to Des Moines flight deals. Data was last updated June 12, 2025.

Round-trip from

$271
(American Airlines)

One-way from

$149
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$456
From Durham to Des Moines
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One-way flight from Durham to Des Moines
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Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Durham to Des Moines

Cheapest flights from Durham to Des Moines
Explore the most affordable flight options available from Durham to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:39 pmRDU - DSM
1 stop6h 51mAmerican Airlines
Mon 9/225:11 amDSM - RDU
1 stop7h 50mAmerican Airlines
Deal found 6/11$271
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2610:35 amRDU - DSM
2 stops32h 36mMultiple Airlines
Sun 6/296:32 pmDSM - RDU
2 stops22h 49mMultiple Airlines
Deal found 6/10$289
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/265:25 pmRDU - DSM
1 stop6h 08mDelta
Sat 8/23:00 pmDSM - RDU
1 stop7h 19mDelta
Deal found 6/11$297
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/146:00 amRDU - DSM
2 stops7h 23mUnited Airlines
Wed 9/1711:35 amDSM - RDU
1 stop4h 29mUnited Airlines
Deal found 6/10$306
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/87:35 amRDU - DSM
1 stop4h 25mSouthwest
Thu 7/101:35 pmDSM - RDU
1 stop8h 55mSouthwest
Deal found 6/10$332
This FlightHub deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/135:23 pmRDU - DSM
1 stop26h 25mFrontier
Fri 7/187:33 pmDSM - RDU
1 stop20h 05mFrontier
Deal found 6/12$488

Cheapflights Fare Finder

Customize your flight search to find flights from Durham to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Durham to Des Moines that are best for you.

Fly from

Durham

Fly to

Des Moines

Route

Depart

Return

Price

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Thu 8/7

8:19 pm-11:45 pm

1 stop4h 26m

Des Moines

Mon 8/11

3:20 pm-11:59 pm

1 stop7h 39m

$271

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Thu 6/26

10:35 am-6:11 pm

2 stops32h 36m

Des Moines

Sun 6/29

6:32 pm-6:21 pm

2 stops22h 49m

$289

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Sat 7/26

6:45 pm-10:33 pm

1 stop4h 48m

Des Moines

Sat 8/2

3:00 pm-11:19 pm

1 stop7h 19m

$297

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Fri 7/4

3:10 pm-9:47 pm

2 stops7h 37m

Des Moines

Tue 7/8

6:24 am-2:13 pm

2 stops6h 49m

$307

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Tue 7/8

7:35 am-11:00 am

1 stop4h 25m

Des Moines

Thu 7/10

5:25 am-4:30 pm

2 stops10h 05m

$337

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Sun 7/13

5:23 pm-6:48 pm

1 stop26h 25m

Des Moines

Fri 7/18

7:33 pm-4:38 pm

1 stop20h 05m

$488

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Tue 7/29

3:38 pm-10:06 pm

1 stop7h 28m

$149

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Tue 7/29

3:10 pm-9:47 pm

2 stops7h 37m

$189

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Mon 7/28

5:15 pm-11:50 pm

2 stops7h 35m

$219

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Sun 6/15

5:18 pm-7:53 pm

1 stop27h 35m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 11 results
1
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Best time to book a flight from Durham to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Des Moines

How far ahead should I book a flight from Durham to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Des Moines. Price data was last updated on June 9, 2025.

To ensure you get the cheapest price possible for a flight from Durham to Des Moines, you should look to book at least 48 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Durham to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Durham to Des Moines (average of $336). Flying from Durham to Des Moines in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to DSM?

Find hourly flight availability from Durham to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Durham to Des Moines as you normally would.

What is the cheapest day to fly from Durham to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Durham to Des Moines. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Durham to Des Moines flight should consider departing on Tuesday at noon when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 12, 2025.
To help decide which airline to fly from Durham to Des Moines, see what other customers have to say about Southwest, Delta and United Airlines. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Comfort

8.0

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Comfort

8.0

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Comfort

8.0

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Comfort

8.0

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Comfort

8.0

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Frontier
5.9
Fair
3,295 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Comfort

8.0

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Durham to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Durham?

    If you book a flight to Des Moines from Durham, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines. There are 0 flights from Durham to Des Moines per day from 4 different airlines.

  • What are the cheapest airlines to fly from Durham to Des Moines one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $149. United Airlines flights start at $189 while deals on Southwest start at $219 one-way.

  • Can I find deals for flights from Durham to Des Moines that include hotel bookings?

    Yes. In addition to deals on Durham to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Des Moines.

  • Can I find deals for business class flights from Durham to Des Moines?

    Yes. Cheapflights offers flight deals from Durham to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Durham to Des Moines (average of $336). Flying from Durham to Des Moines in June is currently the most expensive (average of $411). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Durham?

Book flights to Durham if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Top 4 airlines flying from Durham to Des Moines

Discover the top 4 airlines that operate flights from Durham to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$237Average$368FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$452FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$417FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$296Average$376FlexibilityNo cancel feeOn-time63%

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