How long is the flight from Durham to Des Moines?

Airlines like United Airlines and Southwest fly from Durham to Des Moines in about 5h 33m. The time it takes to get you to your destination can typically vary by up to 1h 22m. There are 890 mi between Durham and Des Moines. This flight may include one or multiple stops.

What are the cheapest airlines to fly from Durham to Des Moines one-way?

To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $92. Delta flights start at $118 while deals on American Airlines start at $135 one-way.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the most popular airlines that fly from Durham to Des Moines?

When booking a flight from Durham to Des Moines, you may want to consider flying on American Airlines, Delta or Southwest as they are the most popular for this route.

What airport do you fly into for flights to Des Moines from Durham?

If you book a flight to Des Moines from Durham, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines. There are 0 flights from Durham to Des Moines per day from 4 different airlines.

Can I find deals for flights from Durham to Des Moines that include hotel bookings?

Yes. In addition to deals on Durham to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Durham to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Des Moines.

Can I find deals for business class flights from Durham to Des Moines?

Yes. Cheapflights offers flight deals from Durham to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$134+ Flights from Durham to Des Moines

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Cheapflights Tip: The best prices from Durham to Des Moines are usually found in December or August, booked 57 days in advance, depart on a Friday or Wednesday and return on a Wednesday

Cheap flight deals from Durham to Des Moines

Cheapest flights from Durham to Des Moines
Explore the most affordable flight options available from Durham to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Wed 12/316:37 amRDU - DSM

1 stop6h 49mAmerican Airlines

Sun 1/46:26 pmDSM - RDU

1 stop4h 30mAmerican Airlines

Deal found 12/16

$368

Mon 12/295:01 amRDU - DSM

1 stop6h 48mAmerican Airlines

Wed 1/71:16 pmDSM - RDU

1 stop5h 36mAmerican Airlines

Deal found 12/15

$369

Mon 12/296:31 amRDU - DSM

1 stop5h 19mUnited Airlines

Wed 1/78:00 amDSM - RDU

2 stops9h 52mUnited Airlines

Deal found 12/15

$444

Sat 12/2011:40 amRDU - DSM

2 stops22h 16mMultiple Airlines

Mon 12/228:05 amDSM - RDU

1 stop28h 12mMultiple Airlines

Deal found 12/16

$589

Wed 12/178:14 pmRDU - DSM

1 stop27h 12mMultiple Airlines

Fri 12/196:35 amDSM - RDU

1 stop11h 44mMultiple Airlines

Deal found 12/16

$682

Fri 12/266:00 amRDU - DSM

2 stops13h 26mMultiple Airlines

Tue 12/303:45 pmDSM - RDU

1 stop24h 10mMultiple Airlines

Deal found 12/17

$691

Fri 12/268:45 pmRDU - DSM

1 stop4h 20mSouthwest

Tue 12/305:30 amDSM - RDU

1 stop4h 10mSouthwest

Deal found 12/17

$697

Mon 12/225:52 amRDU - DSM

1 stop7h 34mAmerican Airlines

Sun 12/283:27 pmDSM - RDU

1 stop5h 36mAmerican Airlines

Deal found 12/16

$817

Best flights from Durham to Des Moines
Discover carefully curated flight deals from Durham to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Thu 1/153:08 pmRDU - DSM

1 stop8h 38mMultiple Airlines

Mon 1/198:18 pmDSM - RDU

2 stops26h 33mMultiple Airlines

Deal found 12/16

$257

Wed 1/1410:00 amRDU - DSM

1 stop5h 33mUnited Airlines

Wed 1/213:35 pmDSM - RDU

1 stop4h 43mUnited Airlines

Deal found 12/17

$271

Wed 1/143:15 pmRDU - DSM

2 stops6h 55mSouthwest

Wed 1/216:10 amDSM - RDU

1 stop3h 55mSouthwest

Deal found 12/17

$276

Thu 1/159:22 amRDU - DSM

2 stops14h 24mMultiple Airlines

Thu 1/222:58 pmDSM - RDU

1 stop22h 15mMultiple Airlines

Deal found 12/16

$267

Mon 1/125:18 pmRDU - DSM

1 stop5h 32mUnited Airlines

Wed 1/143:04 pmDSM - RDU

1 stop6h 26mUnited Airlines

Deal found 12/16

$292

Tue 1/610:00 amRDU - DSM

1 stop5h 33mUnited Airlines

Thu 1/83:35 pmDSM - RDU

1 stop4h 43mUnited Airlines

Deal found 12/16

$292

Last-minute flights from Durham to Des Moines
Discover last-minute flight deals from Durham to Des Moines. Data last updated December 18, 2025 and is based on user searches.

Tue 1/65:13 pmRDU - DSM

1 stop5h 11mDelta

Tue 1/137:34 amDSM - RDU

1 stop6h 21mDelta

Deal found 12/16

$271

Tue 1/610:00 amRDU - DSM

1 stop5h 33mUnited Airlines

Thu 1/89:03 amDSM - RDU

2 stops8h 49mUnited Airlines

Deal found 12/16

$297

Thu 1/89:46 pmRDU - DSM

1 stop25h 31mMultiple Airlines

Sat 1/175:58 pmDSM - RDU

1 stop14h 35mMultiple Airlines

Deal found 12/16

$235

Mon 1/126:10 amRDU - DSM

2 stops14h 12mMultiple Airlines

Wed 1/146:14 pmDSM - RDU

1 stop13h 38mMultiple Airlines

Deal found 12/16

$265

Mon 1/125:18 pmRDU - DSM

1 stop5h 32mUnited Airlines

Wed 1/143:04 pmDSM - RDU

1 stop6h 26mUnited Airlines

Deal found 12/16

$292

Mon 1/125:35 pmRDU - DSM

1 stop4h 35mSouthwest

Thu 1/155:20 amDSM - RDU

1 stop4h 30mSouthwest

Deal found 12/16

$313

Thu 1/153:08 pmRDU - DSM

1 stop8h 38mMultiple Airlines

Thu 1/222:58 pmDSM - RDU

1 stop22h 15mMultiple Airlines

Deal found 12/16

$248

Thu 1/153:08 pmRDU - DSM

1 stop8h 38mMultiple Airlines

Mon 1/198:18 pmDSM - RDU

2 stops26h 33mMultiple Airlines

Deal found 12/16

$257

One-way flights from Durham to Des Moines
Search for one-way flight options from Durham to Des Moines. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Thu 1/153:08 pmRDU - DSM

1 stop8h 38mMultiple Airlines

Deal found 12/16

$134

Mon 1/124:07 pmRDU - DSM

1 stop8h 37mUnited Airlines

Deal found 12/16

$182

Thu 1/156:00 amRDU - DSM

3 stops17h 30mUnited Airlines

Deal found 12/16

$202

Fri 12/269:26 amRDU - DSM

1 stop4h 28mAmerican Airlines

Deal found 12/17

$349

Fri 12/265:30 amRDU - DSM

2 stops6h 30mSouthwest

Deal found 12/17

$354

Fri 12/269:47 pmRDU - DSM

3 stops45h 53mMultiple Airlines

Deal found 12/17

$447

Find flight deals from Durham to Des Moines

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$235 (Kiwi.com)
One-way from	$134 (Kiwi.com)
Popular in	February
Cheapest in	December
Average price	$333

Provider with most accurate pricing for Raleigh-Durham-Des Moines flight deals.

Search Deals

Provider most trusted by Cheapflights users for Raleigh-Durham-Des Moines flights.

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From Durham to Des Moines

Search Deals

One-way flight from Durham to Des Moines

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($49 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Thu 1/15

3:08 pm-10:46 pm

1 stop8h 38m

Des Moines

Mon 1/19

8:18 pm-11:51 pm

2 stops26h 33m

$257

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Thu 1/15

9:22 am-10:46 pm

2 stops14h 24m

Des Moines

Thu 1/22

2:58 pm-2:13 pm

1 stop22h 15m

$267

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 1/14

10:00 am-2:33 pm

1 stop5h 33m

Des Moines

Wed 1/21

3:35 pm-9:18 pm

1 stop4h 43m

$271

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 1/14

3:15 pm-9:10 pm

2 stops6h 55m

Des Moines

Wed 1/21

6:10 am-11:05 am

1 stop3h 55m

$276

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Mon 1/12

5:18 pm-9:50 pm

1 stop5h 32m

Des Moines

Wed 1/14

3:04 pm-10:30 pm

1 stop6h 26m

$292

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Tue 1/6

10:00 am-2:33 pm

1 stop5h 33m

Des Moines

Thu 1/8

3:35 pm-9:18 pm

1 stop4h 43m

$292

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Thu 1/15

3:08 pm-10:46 pm

1 stop8h 38m

$134

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Mon 1/12

4:07 pm-11:44 pm

1 stop8h 37m

$182

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Thu 1/15

6:00 am-10:30 pm

3 stops17h 30m

$202

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Fri 12/26

9:26 am-12:54 pm

1 stop4h 28m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 12 results

Best time to book a flight from Durham to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Durham with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Des Moines

How far ahead should I book a flight from Durham to Des Moines?

To ensure you get the cheapest price possible for a flight from Durham to Des Moines, you should look to book at least 56 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Durham to Des Moines?

Currently, May is the cheapest month in which you can book a flight from Durham to Des Moines (average of $209). Flying from Durham to Des Moines in November is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to DSM?

Unlike in the evening, when flights are generally more expensive, you can save up to 19% on flights from Durham to Des Moines by exploring options for tickets at noon.

Reviews of airlines servicing Des Moines

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Durham to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,005 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,091 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,054 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly into for flights to Des Moines from Durham?
If you book a flight to Des Moines from Durham, you will be flying to Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines. There are 0 flights from Durham to Des Moines per day from 4 different airlines.
How long is the flight from Durham to Des Moines?
Airlines like United Airlines and Southwest fly from Durham to Des Moines in about 5h 33m. The time it takes to get you to your destination can typically vary by up to 1h 22m. There are 890 mi between Durham and Des Moines. This flight may include one or multiple stops.
What are the cheapest airlines to fly from Durham to Des Moines one-way?
To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $92. Delta flights start at $118 while deals on American Airlines start at $135 one-way.
Can I find deals for flights from Durham to Des Moines that include hotel bookings?
Yes. In addition to deals on Durham to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Durham to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Des Moines.
Can I find deals for business class flights from Durham to Des Moines?
Yes. Cheapflights offers flight deals from Durham to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Durham to Des Moines?
Currently, May is the cheapest month in which you can book a flight from Durham to Des Moines (average of $209). Flying from Durham to Des Moines in November is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Altoona

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Boone

Ames

Clive

West Des Moines

Ankeny

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Other flights to Des Moines

Top 4 airlines flying from Durham to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$242	Average$366	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$248	Average$330	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$292	Average$384	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$320	Average$418	FlexibilityNo cancel fee	On-time69%

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$134+ Cheap flights from Durham, NC to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Durham to Des Moines with Cheapflights

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Cheapflights Tip: The best prices from Durham to Des Moines are usually found in December or August, booked 57 days in advance, depart on a Friday or Wednesday and return on a Wednesday

Cheap flight deals from Durham to Des Moines

Cheapest flights from Durham to Des MoinesExplore the most affordable flight options available from Durham to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Durham to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Durham to Des Moines

Keep the following information in mind while searching for Durham to Des Moines flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Durham to Des Moines that are best for you.

Best time to book a flight from Durham to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Durham with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Durham to Des Moines

How far ahead should I book a flight from Durham to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Des Moines. Price data was last updated on December 12, 2025.

What is the cheapest month to book a flight from Durham to Des Moines?

What is the cheapest time of day to fly from DU8 to DSM?

Find hourly flight availability from Durham to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Reviews of airlines servicing Des Moines

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Durham to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Durham to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Des Moines from Durham?

How long is the flight from Durham to Des Moines?

What are the cheapest airlines to fly from Durham to Des Moines one-way?

Can I find deals for flights from Durham to Des Moines that include hotel bookings?

How can I find direct flights from Durham to Des Moines?

Can I find deals for business class flights from Durham to Des Moines?

What is the cheapest month to book a flight from Durham to Des Moines?

Traveling to a place near Des Moines?

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Alternative routes for Durham to Des Moines

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Top 4 airlines flying from Durham to Des Moines

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Cheapest flights from Durham to Des Moines
Explore the most affordable flight options available from Durham to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.