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$261+ Cheap flights from Florence, SC (FLO) to Colorado

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DEN
Oct 22 — Oct 291
Wed 10/22
Wed 10/29
1 adult, Economy
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Cheap flight deals from Florence to Colorado

Keep the following information in mind while searching for Florence to Colorado flight deals. Data was last updated September 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$577
(American Airlines)

One-way from

$261
(American Airlines)
Provider with most accurate pricing for Florence-Denver Intl flight deals.
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Provider most trusted by Cheapflights users for Florence-Denver Intl flights.
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From Florence to Colorado
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One-way flight from Florence to Colorado
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Find flight deals from Florence to Colorado

Cheapest flights from Florence to Colorado
Explore the most affordable flight options available from Florence to Colorado. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2025.

This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:14 amFLO - DEN
1 stop8h 20mAmerican Airlines
Sat 10/111:52 pmDEN - FLO
1 stop8h 11mAmerican Airlines
Deal found 9/22$577
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:37 pmFLO - DEN
1 stop6h 30mAmerican Airlines
Sat 10/47:09 amDEN - FLO
1 stop8h 03mAmerican Airlines
Deal found 9/22$599
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:37 pmFLO - DEN
1 stop6h 25mAmerican Airlines
Sun 9/283:57 pmDEN - FLO
1 stop6h 16mAmerican Airlines
Deal found 9/22$616
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:37 pmFLO - DEN
1 stop6h 30mAmerican Airlines
Fri 10/33:08 pmDEN - FLO
1 stop6h 08mAmerican Airlines
Deal found 9/22$641
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:14 amFLO - DEN
2 stops11h 31mAmerican Airlines
Sun 10/58:10 amDEN - FLO
1 stop6h 22mAmerican Airlines
Deal found 9/22$646
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:27 pmFLO - DEN
2 stops11h 42mAmerican Airlines
Sat 10/412:41 pmDEN - FLO
2 stops8h 35mAmerican Airlines
Deal found 9/22$651

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Colorado that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 22, 2025.
Use the filters below to find and compare flights from Florence to Colorado that are best for you.

Fly from

Florence

Fly to

Colorado

Route

Depart

Return

Price

FlorenceDenver

FLO - DEN

FLODEN

Florence

Tue 10/7

3:19 pm-10:05 pm

2 stops8h 46m

Denver Intl

Sat 10/11

4:00 pm-12:03 am

1 stop6h 03m

$582

FlorenceDenver

FLO - DEN

FLODEN

Florence

Sat 9/27

5:37 pm-10:07 pm

1 stop6h 30m

Denver Intl

Sat 10/4

7:09 am-5:12 pm

1 stop8h 03m

$599

FlorenceDenver

FLO - DEN

FLODEN

Florence

Fri 9/26

5:37 pm-10:02 pm

1 stop6h 25m

Denver Intl

Sat 10/4

7:09 am-5:12 pm

1 stop8h 03m

$641

FlorenceDenver

FLO - DEN

FLODEN

Florence

Sat 9/27

5:37 pm-10:07 pm

1 stop6h 30m

Denver Intl

Fri 10/3

3:08 pm-11:16 pm

1 stop6h 08m

$641

FlorenceDenver

FLO - DEN

FLODEN

Florence

Sun 9/28

5:14 am-8:56 am

1 stop5h 42m

Denver Intl

Sat 10/4

3:08 pm-11:16 pm

1 stop6h 08m

$641

FlorenceDenver

FLO - DEN

FLODEN

Florence

Sat 9/27

6:14 am-9:53 am

1 stop5h 39m

Denver Intl

Sun 10/5

7:11 am-4:32 pm

1 stop7h 21m

$641

FlorenceDenver

FLO - DEN

FLODEN

Florence

Tue 10/21

6:14 am-4:38 pm

2 stops12h 24m

$261

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/20

Best time to book a flight from Florence to Colorado

Have a flexible travel schedule? Discover the best time to fly to Colorado from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Colorado

What is the cheapest month to book a flight from Florence, South Carolina to Colorado?

Currently, October is the cheapest month in which you can book a flight from Florence, South Carolina to Colorado (average of $197). Flying from Florence, South Carolina to Colorado in March is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Colorado. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Colorado?

    Located just 2.3 mi from the city center, Florence (FLO) is the airport most travelers will use when flying to Colorado from Florence.

  • How long is the flight from Florence, South Carolina to Colorado?

    Airlines like American Airlines fly from Florence, South Carolina to Colorado in about 8h 46m. The time it takes to get you to your destination can typically vary by up to . The distance between Florence, South Carolina and Colorado is about 1425 mi.

  • Can I find deals for flights from Florence to Colorado that include hotel bookings?

    Yes. In addition to deals on Florence to Colorado flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Colorado?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Colorado.

  • Can I find deals for business class flights from Florence to Colorado?

    Yes. Cheapflights offers flight deals from Florence to Colorado by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Colorado?

    Currently, October is the cheapest month in which you can book a flight from Florence, South Carolina to Colorado (average of $197). Flying from Florence, South Carolina to Colorado in March is currently the most expensive (average of $278). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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