$245+ Cheap flights from Des Moines to Cleveland (DSM - CLE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLE
Nov 3 — Nov 101
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Cleveland with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Cleveland
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Best
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One-way
Cheapest flights from Des Moines to ClevelandExplore the most affordable flight options available from Des Moines to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
Explore the most affordable flight options available from Des Moines to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 4, 2026.
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 pm -
1 stop4h 56m
Tue 10/271:00 pm -
1 stop6h 09m
Deal found 10/1![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
2 stops10h 25m
Mon 11/167:10 pm -
1 stop3h 55m
Deal found 10/1![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:52 pm -
1 stop5h 05m
Thu 11/265:00 pm -
1 stop6h 35m
Deal found 10/1![Delta logo]()
$336
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
1 stop8h 05m
Sun 11/158:35 am -
1 stop3h 55m
Deal found 10/1![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:20 am -
1 stop8h 00m
Thu 11/512:35 pm -
2 stops10h 30m
Deal found 10/1![Southwest logo]()
$354
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am -
1 stop3h 50m
Tue 10/277:10 am -
2 stops8h 10m
Deal found 10/1![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:58 pm -
1 stop3h 48m
Wed 12/238:37 pm -
1 stop13h 14m
Deal found 9/29![American Airlines logo]()
$370
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:43 am -
2 stops47h 14m
Tue 10/139:59 pm -
1 stop14h 56m
Deal found 10/2![Multiple Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:25 am -
1 stop3h 45m
Sun 11/88:35 am -
1 stop3h 55m
Deal found 10/2![Southwest logo]()
$385
Best flights from Des Moines to ClevelandDiscover carefully curated flight deals from Des Moines to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
Discover carefully curated flight deals from Des Moines to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 4, 2026.
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:29 pm -
1 stop5h 24m
Mon 11/164:35 pm -
1 stop5h 38m
Deal found 10/1![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:58 pm -
1 stop3h 48m
Wed 12/238:37 pm -
1 stop13h 14m
Deal found 9/29![American Airlines logo]()
$370
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
2 stops10h 25m
Sun 11/157:00 am -
2 stops7h 10m
Deal found 10/1![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:45 pm -
1 stop4h 14m
Wed 10/287:00 am -
1 stop4h 32m
Deal found 9/30![United Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/113:54 pm -
1 stop21h 43m
Tue 10/139:59 pm -
1 stop14h 56m
Deal found 10/2![Multiple Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:52 pm -
1 stop5h 05m
Thu 11/265:00 pm -
1 stop6h 35m
Deal found 10/1![Delta logo]()
$336
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
2 stops10h 25m
Sun 11/157:00 am -
2 stops7h 10m
Deal found 10/1![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:24 am -
1 stop3h 49m
Sun 11/157:00 am -
1 stop4h 19m
Deal found 10/1![Delta logo]()
$353
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:10 am -
2 stops6h 45m
Thu 11/512:35 pm -
2 stops10h 30m
Deal found 10/1![Southwest logo]()
$399
This Southwest deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:25 pm -
2 stops5h 50m
Sun 11/87:00 am -
2 stops7h 10m
Deal found 10/3![Southwest logo]()
$434
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:10 am -
2 stops6h 25m
Wed 12/236:40 am -
2 stops9h 25m
Deal found 9/29![Southwest logo]()
$447
Last-minute flights from Des Moines to ClevelandDiscover last-minute flight deals from Des Moines to Cleveland. Data last updated October 4, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Cleveland. Data last updated October 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:43 am -
2 stops47h 14m
Tue 10/139:59 pm -
1 stop14h 56m
Deal found 10/2![Multiple Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 pm -
1 stop4h 56m
Tue 10/271:00 pm -
1 stop6h 09m
Deal found 10/1![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am -
1 stop3h 50m
Tue 10/277:10 am -
2 stops8h 10m
Deal found 10/1![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:20 am -
1 stop8h 00m
Thu 11/512:35 pm -
2 stops10h 30m
Deal found 10/1![Southwest logo]()
$354
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:25 am -
1 stop3h 45m
Sun 11/88:35 am -
1 stop3h 55m
Deal found 10/2![Southwest logo]()
$385
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am -
1 stop8h 05m
Sun 11/158:35 am -
1 stop3h 55m
Deal found 10/1![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
2 stops10h 25m
Mon 11/167:10 pm -
1 stop3h 55m
Deal found 10/1![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:52 pm -
1 stop5h 05m
Thu 11/265:00 pm -
1 stop6h 35m
Deal found 10/1![Delta logo]()
$336
One-way flights from Des Moines to ClevelandSearch for one-way flight options from Des Moines to Cleveland. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
Search for one-way flight options from Des Moines to Cleveland. Find affordable one-way fares based on user searches. Data last updated October 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:43 am -
2 stops47h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Multiple Airlines logo]()
$245
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1111:27 am -
3 stops11h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![United Airlines logo]()
$907
Find flight deals from Des Moines to Cleveland
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Cleveland (CLE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (Delta) |
One-way from | $245 (Kiwi.com) |
Popular in | April |
Cheapest in | November |
Average price | $366 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
Use the filters below to find and compare flights from Des Moines to Cleveland that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Sun 10/11
8:43 am-8:57 am
2 stops47h 14m
Cleveland Hopkins Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$245
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Wed 11/11
5:29 pm-11:53 pm
1 stop5h 24m
Cleveland Hopkins Intl
Mon 11/16
4:35 pm-9:13 pm
1 stop5h 38m
$309
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Wed 11/25
6:52 pm-12:57 am
1 stop5h 05m
Cleveland Hopkins Intl
Thu 11/26
5:00 pm-10:35 pm
1 stop6h 35m
$336
Quickest round-trip
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Wed 11/11
10:24 am-3:13 pm
1 stop3h 49m
Cleveland Hopkins Intl
Sun 11/15
7:00 am-10:19 am
1 stop4h 19m
$353
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Fri 12/18
7:58 pm-12:46 am
1 stop3h 48m
Cleveland Hopkins Intl
Wed 12/23
8:37 pm-8:51 am
1 stop13h 14m
$370
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Tue 11/10
7:00 am-6:25 pm
2 stops10h 25m
Cleveland Hopkins Intl
Sun 11/15
7:00 am-1:10 pm
2 stops7h 10m
$373
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Wed 11/11
7:00 am-6:25 pm
2 stops10h 25m
Cleveland Hopkins Intl
Sun 11/15
7:00 am-1:10 pm
2 stops7h 10m
$373
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Thu 10/29
5:10 am-12:55 pm
2 stops6h 45m
Cleveland Hopkins Intl
Thu 11/5
12:35 pm-10:05 pm
2 stops10h 30m
$399
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Mon 10/26
6:45 pm-11:59 pm
1 stop4h 14m
Cleveland Hopkins Intl
Wed 10/28
7:00 am-10:32 am
1 stop4h 32m
$409
Des MoinesCleveland
DSM Des Moines - CLE Cleveland Hopkins Intl
DSMCLE
Des Moines
Fri 11/6
4:25 pm-11:15 pm
2 stops5h 50m
Cleveland Hopkins Intl
Sun 11/8
7:00 am-1:10 pm
2 stops7h 10m
$434
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Cleveland
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Cleveland in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Cleveland flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Cleveland flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Cleveland flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Cleveland flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Cleveland flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Cleveland
Have a flexible travel schedule? Discover the best time to fly to Cleveland from Des Moines with our price prediction graph.
DSM-CLE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Cleveland
Reviews of airlines servicing Cleveland
Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated October 4, 2026.
See what other customers who have flown with Delta and United Airlines from Des Moines to Cleveland have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Cleveland?
Book flights to Cleveland if you plan to visit one of these locationsSandusky
Beachwood
Independence
Mansfield
Strongsville
Lakewood
Avon
Medina
Streetsboro
North Olmsted
Cuyahoga Falls
Kent
Westlake
Elyria
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Other flights to Cleveland
Explore flights to Cleveland departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 4, 2026.
Complete your trip
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Des Moines and Cleveland flights
Browse other Des Moines and Cleveland flight options. Last updated on October 4, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on October 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Des Moines to Cleveland
Discover the top 3 airlines that operate flights from Des Moines to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$237 | Average$372 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$294 | Average$386 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$320 | Average$446 | FlexibilityNo cancel fee | On-time69% |